Constitutive phosphorylation of the Parkinson's disease associated α- synuclein

Journal of Biological Chemistry

Volumn 275, Issue 1, 2000, Pages 390-397

  Okochi, Masayasu ^a   Walter, Jochen ^a   Koyama, Akihiko ^b   Nakajo, Shigeo ^d   Baba, Minami ^b   Iwatsubo, Takeshi ^b   Meijer, Laurent ^c   Kahle, Philipp J ^a   Haass, Christian ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF TOKYO   (Japan)

^c STATION BIOLOGIQUE   (France)

^d Dept of Biochemistry ^*

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; CASEIN KINASE I; OKADAIC ACID; PHOSPHATASE; SERINE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONSENSUS SEQUENCE; DEPHOSPHORYLATION; GENE MUTATION; HUMAN; HUMAN CELL; KIDNEY CELL; LEWY BODY; NONHUMAN; PARKINSON DISEASE; PEPTIDE MAPPING; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; RAT; SITE DIRECTED MUTAGENESIS;

ALPHA-SYNUCLEIN; AMINO ACID SEQUENCE; ANIMALS; ANTIBODY SPECIFICITY; BRAIN CHEMISTRY; CASEIN KINASE II; CASEIN KINASES; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NERVE TISSUE PROTEINS; PARKINSON DISEASE; PC12 CELLS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RATS; SERINE; SYNUCLEINS;

ANIMALIA;

EID: 0034614415     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.1.390     Document Type: Article

References (67)

1. Nussbaum, R. L., and Polymeropoulos, M. H. (1997) Hum. Mol. Genet. 6, 1687-1691
2. Clayton, D. F., and George, J. M. (1998) Trends Neurosci. 21, 249-254
3. Polymeropoulos, M. H., Lavedan, C., Leroy, E., Ide, S. E., Dehejia, A., Pike, B., Root, H., Rubenstein, J., Boyer, R., Stenroos, E. S., Chandrasekharappa, S., Athanassiadou, A., Papapetropoulos, T., Johnson, W. G., Lazzarini, A. M., Duvoisin, R. C., Di Iorio, G., Golbe, L. I., and Nussbaum, R. L. (1997) Science 276, 2045-2047
4. Krüger, R., Kuhn, W., Müller, T., Woitalla, D., Graeber, M., Kosel, S., Przuntek, H., Epplen, J. T., Schols, L., and Riess, O. (1998) Nat. Genet. 18, 106-108
5. Farrer, M., Wavrant-DeVrieze, F., Crook, R., Boles, L., Perez-Tur, J., Hardy, J., Johnson, W. G., Steele, J., Maraganore, D., Gwinn, K., and Lynch, T. (1998) Ann. Neurol 43, 394-397
6. Selkoe, D. J. (1996) J. Biol. Chem. 271, 18295-18298
7. Spillantini, M. G., Schmidt, M. L., Lee, V. M., Trojanowski, J. Q., Jakes, R., and Goedert, M. (1997) Nature 388, 839-840
8. Spillantini, M. G., Crowther, R. A., Jakes, R., Hasegawa, M., and Goedert, M. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6469-6473
9. Takeda, A., Mallory, M., Sundsmo, M., Honer, W., Hansen, L., and Masliah, E. (1998) Am. J. Pathol. 152, 367-372
10. Baba, M., Nakajo, S., Tu, P. H., Tomita, T., Nakaya, K., Lee, V. M., Trojanowski, J. Q., and Iwatsubo, T. (1998) Am. J. Pathol. 152, 879-884
11. Spillantini, M. G., Crowther, R. A., Jakes, R., Cairns, N. J., Lantos, P. L., and Goedert, M. (1998) Neurosci. Lett. 251, 205-208
12. Gai, W. P., Power, J. H., Blumbergs, P. C., and Blessing, W. W. (1998) Lancet 352, 547-548
13. Arima, K., Ueda, K., Sunohara, N., Hirai, S., Izumiyama, Y., Tonozuka-Uehara, H., and Kawai, M. (1998) Brain Res. 808, 93-100
14. Tu, P. H., Galvin, J. E., Baba, M., Giasson, B., Tomita, T., Leight, S., Nakajo, S., Iwatsubo, T., Trpojanowski, J. Q., and Lee, V. M. (1998) Ann. Neurol. 44, 415-422
15. Wakabayashi, K., Hayashi, S., Kakita, A., Yamada, M., Toyoshima, Y., Yoshimoto, M., and Takahashi, H. (1998) Acta Neuropathol. 96, 445-452
16. Wakabayashi, K., Yoshimoto, M., Tsuji, S., and Takahashi, H. (1998) Neurosci. Lett. 249, 180-182
17. Arawaka, S., Saito, Y., Murayama, S., and Mori, H. (1998) Neurology 51, 887-889
18. Lippa, C. F., Fujiwara, H., Mann, D. M., Giasson, B., Baba, M., Schmidt, M. L., Nee, L. E., O'Connell, B., Pollen, D. A., St. George-Hyslop, P. S., Ghetti, B., Nochlin, D. Bird, T. D., Cairns, N. J., Lee, V. M., Iwatsubo, T., and Trojanowski, J. Q. (1998) Am. J. Pathol. 153, 1365-1370
19. Ueda, K., Fukushima, H., Masliah, E., Xia, Y., Iwai, A., Yoshimoto, M., Otero, D. A., Kondo, J., Ihara, Y., and Saitoh, T. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 11282-11286
20. Teplow, D. B. (1998) Amyloid 5, 121-142
21. Lansbury, P. T., Jr. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 3342-3344
22. Conway, K. A., Harper, J. D., and Lansbury, P. T. (1998) Nat. Med. 4, 1318-1320
23. Crowther, R. A., Jakes, R., Spillantini, M. G., and Goedert, M. (1998) FEBS Lett. 436, 309-312
24. Hashimoto, M., Hsu, L. J., Sisk, A., Xia, Y., Takeda, A., Sundsmo, M., and Masliah, E. (1998) Brain Res. 799, 301-306
25. Narhi, L., Wood, S. J., Steavenson, S., Jiang, Y., Wu, G. M., Anafi, D., Kaufman, S. A., Martin, F., Sitney, K., Denis, P., Louis, J. C., Wypych, J., Biere, A. L., and Citron, M. (1999) J. Biol. Chem. 274, 9843-9846
26. Giasson, B. I., Uryu, K., Trojanowski, J. Q., and Lee, V. M.-Y. (1999) J. Biol. Chem. 274, 7619-7622
27. Maroteaux, L., Campanelli, J. T., and Scheller, R. H. (1988) J. Neurosci. 8, 2804-2815
28. Maroteaux, L., and Scheller, R. H. (1991) Mol. Brain Res. 11, 335-343
29. Shibayama-Imazu, T., Okahashi, I., Omata, K., Nakajo, S., Ochiai, H., Nakai, Y., Hama, T., Nakamura, Y., and Nakaya, K. (1993) Brain Res. 622, 17-25
30. Jakes, R., Spillantini, M. G., and Goedert, M. (1994) FEBS Lett. 345, 27-32
31. George, J. M., Jin, H., Woods, W. S., and Clayton, D. F. (1995) Neuron 15, 361-372
32. Iwai, A., Masliah, E., Yoshimoto, M., Ge, N., Flanagan, L., de Silva, H. A., Kittel, A., and Saitoh, T. (1995) Neuron 14, 467-475
33. Irizarry, M. C., Kim, T. W., McNamara, M., Tanzi, R. E., George, J. M., Clayton, D. F., and Hyman, B. T. (1996) J. Neuropathol. Exp. Neurol. 55, 889-895
34. Jensen, P. H., Nielsen, M. S., Jakes, R., Dotti, C. G., and Goedert, M. (1998) J. Biol. Chem. 273, 26292-26294
35. Davidson, W. S., Jonas, A., Clayton, D. F., and George, J. M. (1998) J. Biol. Chem. 273, 9443-9449
36. Nakajo, S., Tsukada, K., Omata, K., Nakamura, Y., and Nakaya, K. (1993) Eur. J. Biochem. 21, 1057-1063
37. Tomita, T., Chang, T. Y., Kodama, T., and Iwatsubo, T. (1998) Neuroreport 5, 911-913
38. Steiner, H., Capell, A., Pesold, B., Citron, M., Koetzel, P. M., Selkoe, D. J., Romig, H., Mendla, K., and Haass, C. (1998) J. Biol. Chem. 273, 32322-32331
39. Grunberg, J., Walter, J., Loetscher, H., Deuschle, U., Jacobsen, H., and Haass, C. (1998) Biochemistry 37, 2263-2270
40. Cohen, P. (1991) Methods Enzymol. 201, 389-398
41. Desdouits, F., Cohen, D., Nairn, A. C., Greengard, P., and Girault, J.-A. (1995) J. Biol. Chem. 270, 8772-8778
42. Zandomeni, R., Zandomeni, M. C., Shugar, D., and Weinmann, R. (1986) J. Biol. Chem. 261, 3414-3419
43. Huang, F. L., Yoshida, Y., and Huang, K. P. (1991) Methods Enzymol. 200, 454-463
44. Julinek, T., and Weber, M. J. (1993) Biotechnique 15, 620-629
45. Boyle, W. J., van der Geer, P., and Hunter, T. (1991) Methods Enzymol. 201, 110-149
46. Fernandez, J., Andrews, L., and Mische, S. M. (1994) Anal. Biochem. 218, 112-117
47. Nakajo, S., Omata, K., Aiuchi, T., Shibayama, T., Okahashi, H., Nakai, Y., Nakaya, K., and Nakamura, Y. (1990) J. Neurochem. 55, 2031-2038
48. Shibayama-Imazu, T., Okahashi, I., Omata, K., Nakajo, S., Ochiai, H., Nakai, Y., Hama, T., Nakamura, Y., and Nakaya, K. (1993) Brain Res. 622, 17-25
49. Seeger, M., Nordstedt, C., Petanceska, S., Kovacs, D. M., Gouras, G. K., Hahne, S., Fraser, P., Levesque, L., Czernik, A. J., St. George-Hyslop, P. S., Sisodia, S. S., Thinakaran, G., Tanzi, R. E., Greengard, P., and Gandy, S. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 5090-5094
50. Walter, J., Grünberg, J., Capell, A., Pesold, B., Schindzielorz, A., Citron, M., Mendla, K., St. George-Hyslop, P. S., Multhaup, G., Selkoe, D. J., and Haass, C. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 5349-5354
51. Walter, J., Grünberg, J., Schindzielorz, A., and Haass, C. (1998) Biochemistry 37, 5961-5967
52. Pearson, R. B., and Kemp, B. E. (1991) Methods Enzymol. 200, 62-81
53. Marshak, D. R., and Carroll, D. (1991) Methods Enzymol. 200, 134-156
54. Ueda, K., Saitoh, T., and Mori, H. (1994) Biochem. Biophys. Res. Commun. 205, 1366-1372
55. Tuazon, P. T., and Traugh, J. A. (1991) Adv. Second Messenger Phosphoprotein Res. 23, 123-164
56. Ahmed, K. (1994) Cell Mol. Biol. Res. 40, 1-11
57. Tawfic, S., and Ahmed, K. (1994) J. Biol. Chem. 269, 7489-7493
58. Vancura, A., Sessler, A., Leichus, B., and Kuret, J. (1994) J. Biol. Chem. 269, 19271-19278
59. Walter, J., Schnolzer, M., Pyerin, W., Kinzel, V., and Kübler, D. (1996) J. Biol. Chem. 271, 111-119
60. Hollander, B. A., Liang, M. Y., and Besharee, J. C. (1999) Cell Motil. Cytoskeleton 43, 114-127
61. Issinger, O. G. (1993) Pharmacol. Ther. 59, 1-30
62. Guerra, B., and Issinger, O. G. (1999) Electrophoresis 20, 391-408
63. Bennett, M. K., Miller, K. G., and Scheller, R. H. (1993) J. Neurosci. 13, 1701-1707
64. Gross, S. D., Hoffman, D. P., Fisette, P. L., Baas, P., and Anderson, R. A. (1995) J. Cell Biol. 130, 711-724
65. Charriaut-Marlangue, C., Otani, S., Creuzet, C., Ben-Ari, Y., and Loeb, J. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 10232-10236
66. Girault, J. A., Hemmings, H. C., Jr., Williams, K. R., Nairn, A. C., and Greengard, P. (1989) J. Biol. Chem. 264, 21748-21759
67. Diaz-Nido, J., Serrano, L., Mendez, E., and Avila, J. (1988) J. Cell Biol. 106, 2057-2065