-
1
-
-
0024160877
-
Role of Insulin Resistance in Human Disease
-
Reaven, G.M. Role of Insulin Resistance in Human Disease. Diabetes 1988, 37, 1595–1607. [CrossRef] [PubMed]
-
(1988)
Diabetes
, vol.37
, pp. 1595-1607
-
-
Reaven, G.M.1
-
2
-
-
50549090046
-
The metabolic syndrome—From insulin resistance to obesity and diabetes
-
Gallagher, E.J.; LeRoith, D.; Karnieli, E. The metabolic syndrome—From insulin resistance to obesity and diabetes. Endocrinol. Metab. Clin. N. Am. 2008, 37, 559–579. [CrossRef] [PubMed]
-
(2008)
Endocrinol. Metab. Clin. N. Am.
, vol.37
, pp. 559-579
-
-
Gallagher, E.J.1
Leroith, D.2
Karnieli, E.3
-
3
-
-
70350245011
-
Harmonizing the metabolic syndrome: A joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity
-
Alberti, K.G.; Eckel, R.H.; Grundy, S.M.; Zimmet, P.Z.; Cleeman, J.I.; Donato, K.A.; Fruchart, J.C.; James, W.P.; Loria, C.M.; Smith, S.C., Jr.; et al. Harmonizing the metabolic syndrome: A joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 2009, 120, 1640–1645.
-
(2009)
Circulation
, vol.120
, pp. 1640-1645
-
-
Alberti, K.G.1
Eckel, R.H.2
Grundy, S.M.3
Zimmet, P.Z.4
Cleeman, J.I.5
Donato, K.A.6
Fruchart, J.C.7
James, W.P.8
Loria, C.M.9
Smith, S.C.10
-
4
-
-
33745603792
-
The metabolic syndrome: Is this diagnosis necessary?
-
Reaven, G.M. The metabolic syndrome: Is this diagnosis necessary? Am. J. Clin. Nutr. 2006, 83, 1237–1247. [CrossRef] [PubMed]
-
(2006)
Am. J. Clin. Nutr.
, vol.83
, pp. 1237-1247
-
-
Reaven, G.M.1
-
5
-
-
84988904805
-
Prevalence of Obesity Among Adults and Youth: United States, 2011–2014
-
Ogden, C.L.; Carroll, M.D.; Fryar, C.D.; Flegal, K.M. Prevalence of Obesity Among Adults and Youth: United States, 2011–2014. NCHS Data Brief 2015, 219, 1–8.
-
(2015)
NCHS Data Brief
, vol.219
, pp. 1-8
-
-
Ogden, C.L.1
Carroll, M.D.2
Fryar, C.D.3
Flegal, K.M.4
-
6
-
-
67749129442
-
-
accessed on 1 August 2018
-
Obesity and Overweight, Fact Sheet. Available online: http://www.who.int/mediacentre/factsheets/fs311/en/(accessed on 1 August 2018).
-
Obesity and Overweight, Fact Sheet
-
-
-
7
-
-
84865627930
-
-
National Health Statistics Reports; U.S. Department of Health and Human Services: Washington, DC, USA
-
Ervin, R.B. Prevalence of Metabolic Syndrome among Adults 20 Years of Age and Over, by Sex, Age, Race and Ethnicity, and Body Mass Index: United States, 2003–2006; National Health Statistics Reports; U.S. Department of Health and Human Services: Washington, DC, USA, 2009; pp. 1–7.
-
(2009)
Prevalence of Metabolic Syndrome among Adults 20 Years of Age and Over, by Sex, Age, Race and Ethnicity, and Body Mass Index: United States, 2003–2006
, pp. 1-7
-
-
Ervin, R.B.1
-
8
-
-
84929501636
-
Prevalence of the Metabolic Syndrome in the United States, 2003–2012
-
Aguilar, M.; Bhuket, T.; Torres, S.; Liu, B.; Wong, R.J. Prevalence of the Metabolic Syndrome in the United States, 2003–2012. JAMA 2015, 313, 1973–1974. [CrossRef] [PubMed]
-
(2015)
JAMA
, vol.313
, pp. 1973-1974
-
-
Aguilar, M.1
Bhuket, T.2
Torres, S.3
Liu, B.4
Wong, R.J.5
-
9
-
-
53749084198
-
Lipolysis and the integrated physiology of lipid energy metabolism
-
Wang, S.; Soni, K.G.; Semache, M.; Casavant, S.; Fortier, M.; Pan, L.; Mitchell, G.A. Lipolysis and the integrated physiology of lipid energy metabolism. Mol. Genet. Metab. 2008, 95, 117–126. [CrossRef] [PubMed]
-
(2008)
Mol. Genet. Metab.
, vol.95
, pp. 117-126
-
-
Wang, S.1
Soni, K.G.2
Semache, M.3
Casavant, S.4
Fortier, M.5
Pan, L.6
Mitchell, G.A.7
-
10
-
-
0347853481
-
American College of Endocrinology Position Statement on the Insulin Resistance Syndrome
-
Einhorn, D.; Reaven, G.M.; Cobin, R.H.; Ford, E.; Ganda, O.P.; Handelsman, Y.; Hellman, R.; Jellinger, P.S.; Kendall, D.; Krauss, R.M. American College of Endocrinology Position Statement on the Insulin Resistance Syndrome. Endocr. Pract. 2003, 9, 237–252. [PubMed]
-
(2003)
Endocr. Pract.
, vol.9
, pp. 237-252
-
-
Einhorn, D.1
Reaven, G.M.2
Cobin, R.H.3
Ford, E.4
Ganda, O.P.5
Handelsman, Y.6
Hellman, R.7
Jellinger, P.S.8
Kendall, D.9
Krauss, R.M.10
-
11
-
-
84959327330
-
MTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue
-
Albert, V.; Svensson, K.; Shimobayashi, M.; Colombi, M.; Munoz, S.; Jimenez, V.; Handschin, C.; Bosch, F.; Hall, M.N. mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue. EMBO Mol. Med. 2016, 8, 232–246. [CrossRef] [PubMed]
-
(2016)
EMBO Mol. Med.
, vol.8
, pp. 232-246
-
-
Albert, V.1
Svensson, K.2
Shimobayashi, M.3
Colombi, M.4
Munoz, S.5
Jimenez, V.6
Handschin, C.7
Bosch, F.8
Hall, M.N.9
-
12
-
-
25144459980
-
The metabolic syndrome—A new worldwide definition
-
Alberti, K.G.; Zimmet, P.; Shaw, J. The metabolic syndrome—A new worldwide definition. Lancet 2005, 366, 1059–1062. [CrossRef]
-
(2005)
Lancet
, vol.366
, pp. 1059-1062
-
-
Alberti, K.G.1
Zimmet, P.2
Shaw, J.3
-
13
-
-
84893051766
-
Insulin signaling, resistance, and metabolic syndrome: Insights from mouse models into disease mechanisms
-
Guo, S.D. Insulin signaling, resistance, and metabolic syndrome: Insights from mouse models into disease mechanisms. J. Endocrinol. 2014, 220, T1–T23. [CrossRef] [PubMed]
-
(2014)
J. Endocrinol
, vol.220
, pp. T1-T23
-
-
Guo, S.D.1
-
14
-
-
50349088864
-
Transcriptional regulation of the insulin-responsive glucose transporter GLUT4 gene: From physiology to pathology
-
Karnieli, E.; Armoni, M. Transcriptional regulation of the insulin-responsive glucose transporter GLUT4 gene: From physiology to pathology. Am. J. Physiol. Endocrinol. Metab. 2008, 295, E38–E45. [CrossRef] [PubMed]
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.295
, pp. E38-E45
-
-
Karnieli, E.1
Armoni, M.2
-
15
-
-
33947378695
-
Transcriptional regulation of the GLUT4 gene: From PPAR-gamma and FOXO1 to FFA and inflammation
-
Armoni, M.; Harel, C.; Karnieli, E. Transcriptional regulation of the GLUT4 gene: From PPAR-gamma and FOXO1 to FFA and inflammation. Trends Endocrinol. Metab. 2007, 18, 100–107. [CrossRef] [PubMed]
-
(2007)
Trends Endocrinol. Metab.
, vol.18
, pp. 100-107
-
-
Armoni, M.1
Harel, C.2
Karnieli, E.3
-
16
-
-
0037191135
-
Beta-cell dysfunction and insulin resistance in type 2 diabetes—Role of metabolic and genetic abnormalities
-
LeRoith, D. Beta-cell dysfunction and insulin resistance in type 2 diabetes—Role of metabolic and genetic abnormalities. Am. J. Med. 2002, 113, 3S–11S. [CrossRef]
-
(2002)
Am. J. Med.
, vol.113
, pp. 3S-11S
-
-
Leroith, D.1
-
17
-
-
0035130272
-
Beta-cell adaptation and decompensation during the progression of diabetes
-
Weir, G.C.; Laybutt, D.R.; Kaneto, H.; Bonner-Weir, S.; Sharma, A. Beta-cell adaptation and decompensation during the progression of diabetes. Diabetes 2001, 50, S154–S159. [CrossRef] [PubMed]
-
(2001)
Diabetes
, vol.50
, pp. S154-S159
-
-
Weir, G.C.1
Laybutt, D.R.2
Kaneto, H.3
Bonner-Weir, S.4
Sharma, A.5
-
18
-
-
84894502934
-
Beta-Cell dysfunction is associated with metabolic syndrome severity in adults
-
Malin, S.K.; Finnegan, S.; Fealy, C.E.; Filion, J.; Rocco, M.B.; Kirwan, J.P. beta-Cell dysfunction is associated with metabolic syndrome severity in adults. Metab. Syndr. Relat. Disord. 2014, 12, 79–85. [CrossRef] [PubMed]
-
(2014)
Metab. Syndr. Relat. Disord.
, vol.12
, pp. 79-85
-
-
Malin, S.K.1
Finnegan, S.2
Fealy, C.E.3
Filion, J.4
Rocco, M.B.5
Kirwan, J.P.6
-
19
-
-
84969963112
-
Cardiorespiratory fitness is positively associated with increased pancreatic beta cell function independent of fatness in individuals with the metabolic syndrome: Fitness versus fatness
-
Ramos, J.S.; Dalleck, L.C.; Borrani, F.; Fassett, R.G.; Coombes, J.S. Cardiorespiratory fitness is positively associated with increased pancreatic beta cell function independent of fatness in individuals with the metabolic syndrome: Fitness versus fatness. J. Sci. Med. Sport 2017, 20, 45–49. [CrossRef]
-
(2017)
J. Sci. Med. Sport
, vol.20
, pp. 45-49
-
-
Ramos, J.S.1
Dalleck, L.C.2
Borrani, F.3
Fassett, R.G.4
Coombes, J.S.5
-
20
-
-
84892433613
-
Fitness vs. Fatness on all-cause mortality: A meta-analysis
-
Barry, V.W.; Baruth, M.; Beets, M.W.; Durstine, J.L.; Liu, J.; Blair, S.N. Fitness vs. fatness on all-cause mortality: A meta-analysis. Prog. Cardiovasc. Dis. 2014, 56, 382–390. [CrossRef]
-
(2014)
Prog. Cardiovasc. Dis.
, vol.56
, pp. 382-390
-
-
Barry, V.W.1
Baruth, M.2
Beets, M.W.3
Durstine, J.L.4
Liu, J.5
Blair, S.N.6
-
21
-
-
83155189065
-
Long-term effects of changes in cardiorespiratory fitness and body mass index on all-cause and cardiovascular disease mortality in men: The Aerobics Center Longitudinal Study
-
Lee, D.C.; Sui, X.; Artero, E.G.; Lee, I.M.; Church, T.S.; McAuley, P.A.; Stanford, F.C.; Kohl, H.W., 3rd; Blair, S.N. Long-term effects of changes in cardiorespiratory fitness and body mass index on all-cause and cardiovascular disease mortality in men: The Aerobics Center Longitudinal Study. Circulation 2011, 124, 2483–2490. [CrossRef]
-
(2011)
Circulation
, vol.124
, pp. 2483-2490
-
-
Lee, D.C.1
Sui, X.2
Artero, E.G.3
Lee, I.M.4
Church, T.S.5
McAuley, P.A.6
Stanford, F.C.7
Kohl, H.W.8
Blair, S.N.9
-
22
-
-
84892432214
-
The impact of obesity on risk factors and prevalence and prognosis of coronary heart disease-the obesity paradox
-
De Schutter, A.; Lavie, C.J.; Milani, R.V. The impact of obesity on risk factors and prevalence and prognosis of coronary heart disease-the obesity paradox. Prog. Cardiovasc. Dis. 2014, 56, 401–408. [CrossRef]
-
(2014)
Prog. Cardiovasc. Dis.
, vol.56
, pp. 401-408
-
-
de Schutter, A.1
Lavie, C.J.2
Milani, R.V.3
-
23
-
-
75749084041
-
Lean mass index: A better predictor of mortality than body mass index in elderly Asians
-
Han, S.S.; Kim, K.W.; Kim, K.I.; Na, K.Y.; Chae, D.W.; Kim, S.; Chin, H.J. Lean mass index: A better predictor of mortality than body mass index in elderly Asians. J. Am. Geriatr. Soc. 2010, 58, 312–317. [CrossRef]
-
(2010)
J. Am. Geriatr. Soc.
, vol.58
, pp. 312-317
-
-
Han, S.S.1
Kim, K.W.2
Kim, K.I.3
Na, K.Y.4
Chae, D.W.5
Kim, S.6
Chin, H.J.7
-
24
-
-
84901393081
-
Muscle mass index as a predictor of longevity in older adults
-
Srikanthan, P.; Karlamangla, A.S. Muscle mass index as a predictor of longevity in older adults. Am. J. Med. 2014, 127, 547–553. [CrossRef]
-
(2014)
Am. J. Med.
, vol.127
, pp. 547-553
-
-
Srikanthan, P.1
Karlamangla, A.S.2
-
25
-
-
79951591201
-
Mortality risk in older men associated with changes in weight, lean mass, and fat mass
-
Lee, C.G.; Boyko, E.J.; Nielson, C.M.; Stefanick, M.L.; Bauer, D.C.; Hoffman, A.R.; Dam, T.T.; Lapidus, J.A.; Cawthon, P.M.; Ensrud, K.E.; et al. Mortality risk in older men associated with changes in weight, lean mass, and fat mass. J. Am. Geriatr. Soc. 2011, 59, 233–240. [CrossRef]
-
(2011)
J. Am. Geriatr. Soc.
, vol.59
, pp. 233-240
-
-
Lee, C.G.1
Boyko, E.J.2
Nielson, C.M.3
Stefanick, M.L.4
Bauer, D.C.5
Hoffman, A.R.6
Dam, T.T.7
Lapidus, J.A.8
Cawthon, P.M.9
Ensrud, K.E.10
-
26
-
-
84862777882
-
Insulin resistance in the nervous system
-
Kim, B.; Feldman, E.L. Insulin resistance in the nervous system. Trends Endocrinol. Metab. 2012, 23, 133–141. [CrossRef] [PubMed]
-
(2012)
Trends Endocrinol. Metab.
, vol.23
, pp. 133-141
-
-
Kim, B.1
Feldman, E.L.2
-
27
-
-
78650818650
-
Protein kinase B (PKB/Akt), a key mediator of the PI3K signaling pathway
-
Fayard, E.; Xue, G.; Parcellier, A.; Bozulic, L.; Hemmings, B.A. Protein kinase B (PKB/Akt), a key mediator of the PI3K signaling pathway. Curr. Top. Microbiol. Immunol. 2010, 346, 31–56. [PubMed]
-
(2010)
Curr. Top. Microbiol. Immunol.
, vol.346
, pp. 31-56
-
-
Fayard, E.1
Xue, G.2
Parcellier, A.3
Bozulic, L.4
Hemmings, B.A.5
-
28
-
-
85019995736
-
Insulin receptor substrate signaling controls cardiac energy metabolism and heart failure
-
Guo, C.A.; Guo, S. Insulin receptor substrate signaling controls cardiac energy metabolism and heart failure. J. Endocrinol. 2017, 233, R131–R143. [CrossRef] [PubMed]
-
(2017)
J. Endocrinol.
, vol.233
, pp. R131-R143
-
-
Guo, C.A.1
Guo, S.2
-
29
-
-
0036968480
-
Activation of the Glucose Transporter GLUT4 by Insulin
-
Furtado, L.M.; Somwar, R.; Sweeney, G.; Niu, W.; Klip, A. Activation of the Glucose Transporter GLUT4 by Insulin. Biochem. Cell Biol. 2002, 80, 569–578. [CrossRef]
-
(2002)
Biochem. Cell Biol.
, vol.80
, pp. 569-578
-
-
Furtado, L.M.1
Somwar, R.2
Sweeney, G.3
Niu, W.4
Klip, A.5
-
30
-
-
0041903672
-
GLUT4 activation: Thoughts on possible mechanisms
-
Michelle Furtado, L.; Poon, V.; Klip, A. GLUT4 activation: Thoughts on possible mechanisms. Acta Physiol. Scand. 2003, 178, 287–296. [CrossRef]
-
(2003)
Acta Physiol. Scand.
, vol.178
, pp. 287-296
-
-
Michelle Furtado, L.1
Poon, V.2
Klip, A.3
-
31
-
-
77953218866
-
Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue
-
Houde, V.P.; Brûlé, S.; Festuccia, W.T.; Blanchard, P.-G.; Bellmann, K.; Deshaies, Y.; Marette, A. Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue. Diabetes 2010, 59, 1338–1348. [CrossRef]
-
(2010)
Diabetes
, vol.59
, pp. 1338-1348
-
-
Houde, V.P.1
Brûlé, S.2
Festuccia, W.T.3
Blanchard, P.-G.4
Bellmann, K.5
Deshaies, Y.6
Marette, A.7
-
32
-
-
84943405749
-
Protein Tyrosine Phosphatases in Hypothalamic Insulin and Leptin Signaling
-
Zhang, Z.Y.; Dodd, G.T.; Tiganis, T. Protein Tyrosine Phosphatases in Hypothalamic Insulin and Leptin Signaling. Trends Pharm. Sci. 2015, 36, 661–674. [CrossRef]
-
(2015)
Trends Pharm. Sci.
, vol.36
, pp. 661-674
-
-
Zhang, Z.Y.1
Dodd, G.T.2
Tiganis, T.3
-
33
-
-
84866389264
-
Pancreatic beta cell dedifferentiation as a mechanism of diabetic beta cell failure
-
Talchai, C.; Xuan, S.; Lin, H.V.; Sussel, L.; Accili, D. Pancreatic beta cell dedifferentiation as a mechanism of diabetic beta cell failure. Cell 2012, 150, 1223–1234. [CrossRef] [PubMed]
-
(2012)
Cell
, vol.150
, pp. 1223-1234
-
-
Talchai, C.1
Xuan, S.2
Lin, H.V.3
Sussel, L.4
Accili, D.5
-
34
-
-
85059503273
-
SCP4 Promotes Gluconeogenesis through FoxO1/3a Dephosphorylation
-
Cao, J.; Yu, Y.; Zhang, Z.; Chen, X.; Hu, Z.; Tong, Q.; Chang, J.; Feng, X.H.; Lin, X. SCP4 Promotes Gluconeogenesis through FoxO1/3a Dephosphorylation. Diabetes 2017. [CrossRef] [PubMed]
-
(2017)
Diabetes
-
-
Cao, J.1
Yu, Y.2
Zhang, Z.3
Chen, X.4
Hu, Z.5
Tong, Q.6
Chang, J.7
Feng, X.H.8
Lin, X.9
-
35
-
-
0032841435
-
Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling
-
Withers, D.J.; Burks, D.J.; Towery, H.H.; Altamuro, S.L.; Flint, C.L.; White, M.F. Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling. Nat. Genet. 1999, 23, 32–40. [CrossRef] [PubMed]
-
(1999)
Nat. Genet.
, vol.23
, pp. 32-40
-
-
Withers, D.J.1
Burks, D.J.2
Towery, H.H.3
Altamuro, S.L.4
Flint, C.L.5
White, M.F.6
-
36
-
-
80755152887
-
Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice
-
Everard, A.; Lazarevic, V.; Derrien, M.; Girard, M.; Muccioli, G.G.; Neyrinck, A.M.; Possemiers, S.; Van Holle, A.; François, P.; de Vos, W.M.; et al. Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice. Diabetes 2011, 60, 2775–2786. [CrossRef] [PubMed]
-
(2011)
Diabetes
, vol.60
, pp. 2775-2786
-
-
Everard, A.1
Lazarevic, V.2
Derrien, M.3
Girard, M.4
Muccioli, G.G.5
Neyrinck, A.M.6
Possemiers, S.7
van Holle, A.8
François, P.9
de Vos, W.M.10
-
37
-
-
84928006368
-
Insulin resistance and hypertension: New insights
-
Soleimani, M. Insulin resistance and hypertension: New insights. Kidney Int. 2015, 87, 497–499. [CrossRef]
-
(2015)
Kidney Int
, vol.87
, pp. 497-499
-
-
Soleimani, M.1
-
38
-
-
84901248649
-
APPL1 Potentiates Insulin Sensitivity by Facilitating the Binding of IRS1/2 to the Insulin Receptor
-
Ryu, J.; Galan, A.K.; Xin, X.; Dong, F.; Abdul-Ghani, M.A.; Zhou, L.; Wang, C.; Li, C.; Holmes, B.M.; Sloane, L.B.; et al. APPL1 Potentiates Insulin Sensitivity by Facilitating the Binding of IRS1/2 to the Insulin Receptor. Cell Rep. 2014, 7, 1227–1238. [CrossRef] [PubMed]
-
(2014)
Cell Rep
, vol.7
, pp. 1227-1238
-
-
Ryu, J.1
Galan, A.K.2
Xin, X.3
Dong, F.4
Abdul-Ghani, M.A.5
Zhou, L.6
Wang, C.7
Li, C.8
Holmes, B.M.9
Sloane, L.B.10
-
39
-
-
34848912627
-
Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia
-
Cani, P.D.; Neyrinck, A.M.; Fava, F.; Knauf, C.; Burcelin, R.G.; Tuohy, K.M.; Gibson, G.R.; Delzenne, N.M. Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia. Diabetologia 2007, 50, 2374–2383. [CrossRef]
-
(2007)
Diabetologia
, vol.50
, pp. 2374-2383
-
-
Cani, P.D.1
Neyrinck, A.M.2
Fava, F.3
Knauf, C.4
Burcelin, R.G.5
Tuohy, K.M.6
Gibson, G.R.7
Delzenne, N.M.8
-
40
-
-
84901997517
-
PTEN is a protein tyrosine phosphatase for IRS1
-
Shi, Y.; Wang, J.; Chandarlapaty, S.; Cross, J.; Thompson, C.; Rosen, N.; Jiang, X. PTEN is a protein tyrosine phosphatase for IRS1. Nat. Struct. Mol. Biol. 2014, 21, 522–527. [CrossRef]
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 522-527
-
-
Shi, Y.1
Wang, J.2
Chandarlapaty, S.3
Cross, J.4
Thompson, C.5
Rosen, N.6
Jiang, X.7
-
41
-
-
84930737140
-
PTEN upregulation may explain the development of insulin resistance and type 2 diabetes with high dose statins
-
Birnbaum, Y.; Nanhwan, M.K.; Ling, S.; Perez-Polo, J.R.; Ye, Y.; Bajaj, M. PTEN upregulation may explain the development of insulin resistance and type 2 diabetes with high dose statins. Cardiovasc. Drugs 2014, 28, 447–457. [CrossRef]
-
(2014)
Cardiovasc. Drugs
, vol.28
, pp. 447-457
-
-
Birnbaum, Y.1
Nanhwan, M.K.2
Ling, S.3
Perez-Polo, J.R.4
Ye, Y.5
Bajaj, M.6
-
42
-
-
84930938489
-
The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated Proteins
-
Hakuno, F.; Fukushima, T.; Yoneyama, Y.; Kamei, H.; Ozoe, A.; Yoshihara, H.; Yamanaka, D.; Shibano, T.; Sone-Yonezawa, M.; Yu, B.C.; et al. The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated Proteins. Front. Endocrinol. 2015, 6, 73. [CrossRef]
-
(2015)
Front. Endocrinol
, vol.6
, pp. 73
-
-
Hakuno, F.1
Fukushima, T.2
Yoneyama, Y.3
Kamei, H.4
Ozoe, A.5
Yoshihara, H.6
Yamanaka, D.7
Shibano, T.8
Sone-Yonezawa, M.9
Yu, B.C.10
-
43
-
-
84879685325
-
MEMO1, a new IRS1-interacting protein, induces epithelial-mesenchymal transition in mammary epithelial cells
-
Sorokin, A.V.; Chen, J. MEMO1, a new IRS1-interacting protein, induces epithelial-mesenchymal transition in mammary epithelial cells. Oncogene 2013, 32, 3130–3138. [CrossRef] [PubMed]
-
(2013)
Oncogene
, vol.32
, pp. 3130-3138
-
-
Sorokin, A.V.1
Chen, J.2
-
44
-
-
84860388987
-
HSP90 interacting with IRS-2 is involved in cAMP-dependent potentiation of IGF-I signals in FRTL-5 cells
-
Fukushima, T.; Okajima, H.; Yamanaka, D.; Ariga, M.; Nagata, S.; Ito, A.; Yoshida, M.; Asano, T.; Chida, K.; Hakuno, F.; et al. HSP90 interacting with IRS-2 is involved in cAMP-dependent potentiation of IGF-I signals in FRTL-5 cells. Mol. Cell. Endocrinol. 2011, 344, 81–89. [CrossRef] [PubMed]
-
(2011)
Mol. Cell. Endocrinol.
, vol.344
, pp. 81-89
-
-
Fukushima, T.1
Okajima, H.2
Yamanaka, D.3
Ariga, M.4
Nagata, S.5
Ito, A.6
Yoshida, M.7
Asano, T.8
Chida, K.9
Hakuno, F.10
-
45
-
-
84928023583
-
Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity
-
Fukushima, T.; Yoshihara, H.; Furuta, H.; Kamei, H.; Hakuno, F.; Luan, J.; Duan, C.; Saeki, Y.; Tanaka, K.; Iemura, S.; et al. Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity. Nat. Commun. 2015, 6, 6780. [CrossRef] [PubMed]
-
(2015)
Nat. Commun.
, vol.6
, pp. 6780
-
-
Fukushima, T.1
Yoshihara, H.2
Furuta, H.3
Kamei, H.4
Hakuno, F.5
Luan, J.6
Duan, C.7
Saeki, Y.8
Tanaka, K.9
Iemura, S.10
-
46
-
-
0033755408
-
Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia
-
Kubota, N.; Tobe, K.; Terauchi, Y.; Eto, K.; Yamauchi, T.; Suzuki, R.; Tsubamoto, Y.; Komeda, K.; Nakano, R.; Miki, H.; et al. Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia. Diabetes 2000, 49, 1880–1889. [CrossRef] [PubMed]
-
(2000)
Diabetes
, vol.49
, pp. 1880-1889
-
-
Kubota, N.1
Tobe, K.2
Terauchi, Y.3
Eto, K.4
Yamauchi, T.5
Suzuki, R.6
Tsubamoto, Y.7
Komeda, K.8
Nakano, R.9
Miki, H.10
-
47
-
-
0032567937
-
Disruption of IRS-2 causes type 2 diabetes in mice
-
Withers, D.J.; Gutierrez, J.S.; Towery, H.; Burks, D.J.; Ren, J.; Previs, S.; Zhang, Y.; Bernal, D.; Pons, S.; Shulman, G.; et al. Disruption of IRS-2 causes type 2 diabetes in mice. Nature 1998, 391, 900–904. [CrossRef]
-
(1998)
Nature
, vol.391
, pp. 900-904
-
-
Withers, D.J.1
Gutierrez, J.S.2
Towery, H.3
Burks, D.J.4
Ren, J.5
Previs, S.6
Zhang, Y.7
Bernal, D.8
Pons, S.9
Shulman, G.10
-
48
-
-
0028032895
-
Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene
-
Araki, E.; Lipes, M.A.; Patti, M.-E.; Brüning, J.C.; Haag III, B.; Johnson, R.S.; Kahn, C.R. Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene. Nature 1994, 372, 186–190. [CrossRef] [PubMed]
-
(1994)
Nature
, vol.372
, pp. 186-190
-
-
Araki, E.1
Lipes, M.A.2
Patti, M.-E.3
Brüning, J.C.4
Haag, B.5
Johnson, R.S.6
Kahn, C.R.7
-
49
-
-
84898688392
-
High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice
-
Arnold, S.E.; Lucki, I.; Brookshire, B.R.; Carlson, G.C.; Browne, C.A.; Kazi, H.; Bang, S.; Choi, B.R.; Chen, Y.; McMullen, M.F.; et al. High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice. Neurobiol. Dis. 2014, 67, 79–87. [CrossRef]
-
(2014)
Neurobiol. Dis.
, vol.67
, pp. 79-87
-
-
Arnold, S.E.1
Lucki, I.2
Brookshire, B.R.3
Carlson, G.C.4
Browne, C.A.5
Kazi, H.6
Bang, S.7
Choi, B.R.8
Chen, Y.9
McMullen, M.F.10
-
50
-
-
84948973673
-
Hepatitis C virus NS5A promotes insulin resistance through IRS-1 serine phosphorylation and increased gluconeogenesis
-
Parvaiz, F.; Manzoor, S.; Iqbal, J.; Sarkar-Dutta, M.; Imran, M.; Waris, G. Hepatitis C virus NS5A promotes insulin resistance through IRS-1 serine phosphorylation and increased gluconeogenesis. World J. Gastroenterol. 2015, 21, 12361–12369. [CrossRef]
-
(2015)
World J. Gastroenterol.
, vol.21
, pp. 12361-12369
-
-
Parvaiz, F.1
Manzoor, S.2
Iqbal, J.3
Sarkar-Dutta, M.4
Imran, M.5
Waris, G.6
-
51
-
-
84987638170
-
Overexpressing IRS1 in Endothelial Cells Enhances Angioblast Differentiation and Wound Healing in Diabetes and Insulin Resistance
-
Sayaka Katagiri, K.P.; Maeda, Y.; Rao, T.N.; Khamaisi, M.; Li, Q.; Yokomizo, H.; Mima, A.; Lancerotto, L.; Wagers, A.; Orgill, D.P.; et al. Overexpressing IRS1 in Endothelial Cells Enhances Angioblast Differentiation and Wound Healing in Diabetes and Insulin Resistance. Diabetes 2016, 65, 2760–2771. [CrossRef]
-
(2016)
Diabetes
, vol.65
, pp. 2760-2771
-
-
Sayaka Katagiri, K.P.1
Maeda, Y.2
Rao, T.N.3
Khamaisi, M.4
Li, Q.5
Yokomizo, H.6
Mima, A.7
Lancerotto, L.8
Wagers, A.9
Orgill, D.P.10
-
52
-
-
78349297565
-
Oxidative Stress and Diabetic Complications
-
Giacco, F.; Brownlee, M. Oxidative Stress and Diabetic Complications. Circ. Res. 2010, 107, 1058–1070. [CrossRef]
-
(2010)
Circ. Res.
, vol.107
, pp. 1058-1070
-
-
Giacco, F.1
Brownlee, M.2
-
53
-
-
84879849847
-
Regulation of IRS1/Akt insulin signaling by microRNA-128a during myogenesis
-
Motohashi, N.; Alexander, M.S.; Shimizu-Motohashi, Y.; Myers, J.A.; Kawahara, G.; Kunkel, L.M. Regulation of IRS1/Akt insulin signaling by microRNA-128a during myogenesis. J. Cell Sci. 2013, 126, 2678–2691. [CrossRef] [PubMed]
-
(2013)
J. Cell Sci.
, vol.126
, pp. 2678-2691
-
-
Motohashi, N.1
Alexander, M.S.2
Shimizu-Motohashi, Y.3
Myers, J.A.4
Kawahara, G.5
Kunkel, L.M.6
-
54
-
-
84899490560
-
MicroRNA-145 suppresses hepatocellular carcinoma by targeting IRS1 and its downstream Akt signaling
-
Wang, Y.; Hu, C.; Cheng, J.; Chen, B.; Ke, Q.; Lv, Z.; Wu, J.; Zhou, Y. MicroRNA-145 suppresses hepatocellular carcinoma by targeting IRS1 and its downstream Akt signaling. Biochem. Biophys. Res. Commun. 2014, 446, 1255–1260. [CrossRef] [PubMed]
-
(2014)
Biochem. Biophys. Res. Commun.
, vol.446
, pp. 1255-1260
-
-
Wang, Y.1
Hu, C.2
Cheng, J.3
Chen, B.4
Ke, Q.5
Lv, Z.6
Wu, J.7
Zhou, Y.8
-
55
-
-
84897108634
-
Downregulation of IRS-1 in adipose tissue of offspring of obese mice is programmed cell-autonomously through post-transcriptional mechanisms
-
Fernandez-Twinn, D.S.; Alfaradhi, M.Z.; Martin-Gronert, M.S.; Duque-Guimaraes, D.E.; Piekarz, A.; Ferland-McCollough, D.; Bushell, M.; Ozanne, S.E. Downregulation of IRS-1 in adipose tissue of offspring of obese mice is programmed cell-autonomously through post-transcriptional mechanisms. Mol. Metab. 2014, 3, 325–333. [CrossRef] [PubMed]
-
(2014)
Mol. Metab.
, vol.3
, pp. 325-333
-
-
Fernandez-Twinn, D.S.1
Alfaradhi, M.Z.2
Martin-Gronert, M.S.3
Duque-Guimaraes, D.E.4
Piekarz, A.5
Ferland-McCollough, D.6
Bushell, M.7
Ozanne, S.E.8
-
56
-
-
9644260562
-
Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus
-
Kubota, N.; Terauchi, Y.; Tobe, K.; Yano, W.; Suzuki, R.; Ueki, K.; Takamoto, I.; Satoh, H.; Maki, T.; Kubota, T.; et al. Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus. J. Clin. Investig. 2004, 114, 917–927. [CrossRef] [PubMed]
-
(2004)
J. Clin. Investig.
, vol.114
, pp. 917-927
-
-
Kubota, N.1
Terauchi, Y.2
Tobe, K.3
Yano, W.4
Suzuki, R.5
Ueki, K.6
Takamoto, I.7
Satoh, H.8
Maki, T.9
Kubota, T.10
-
57
-
-
84928207852
-
Insulin receptor substrate-2 (Irs2) in endothelial cells plays a crucial role in insulin secretion
-
Hashimoto, S.; Kubota, N.; Sato, H.; Sasaki, M.; Takamoto, I.; Kubota, T.; Nakaya, K.; Noda, M.; Ueki, K.; Kadowaki, T. Insulin receptor substrate-2 (Irs2) in endothelial cells plays a crucial role in insulin secretion. Diabetes 2015, 64, 876–886. [CrossRef] [PubMed]
-
(2015)
Diabetes
, vol.64
, pp. 876-886
-
-
Hashimoto, S.1
Kubota, N.2
Sato, H.3
Sasaki, M.4
Takamoto, I.5
Kubota, T.6
Nakaya, K.7
Noda, M.8
Ueki, K.9
Kadowaki, T.10
-
58
-
-
84881307201
-
Serine phosphorylation sites on IRS2 activated by angiotensin II and protein kinase C to induce selective insulin resistance in endothelial cells
-
Park, K.; Li, Q.; Rask-Madsen, C.; Mima, A.; Mizutani, K.; Winnay, J.; Maeda, Y.; D’Aquino, K.; White, M.F.; Feener, E.P.; et al. Serine phosphorylation sites on IRS2 activated by angiotensin II and protein kinase C to induce selective insulin resistance in endothelial cells. Mol. Cell. Biol. 2013, 33, 3227–3241. [CrossRef]
-
(2013)
Mol. Cell. Biol.
, vol.33
, pp. 3227-3241
-
-
Park, K.1
Li, Q.2
Rask-Madsen, C.3
Mima, A.4
Mizutani, K.5
Winnay, J.6
Maeda, Y.7
D’Aquino, K.8
White, M.F.9
Feener, E.P.10
-
59
-
-
84878747826
-
Phosphorylation of serine 1137/1138 of mouse insulin receptor substrate (IRS) 2 regulates cAMP-dependent binding to 14-3-3 proteins and IRS2 protein degradation
-
Neukamm, S.S.; Ott, J.; Dammeier, S.; Lehmann, R.; Haring, H.U.; Schleicher, E.; Weigert, C. Phosphorylation of serine 1137/1138 of mouse insulin receptor substrate (IRS) 2 regulates cAMP-dependent binding to 14-3-3 proteins and IRS2 protein degradation. J. Biol. Chem. 2013, 288, 16403–16415. [CrossRef]
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 16403-16415
-
-
Neukamm, S.S.1
Ott, J.2
Dammeier, S.3
Lehmann, R.4
Haring, H.U.5
Schleicher, E.6
Weigert, C.7
-
60
-
-
84877921698
-
IRS2 is a candidate driver oncogene on 13q34 in colorectal cancer
-
Day, E.; Poulogiannis, G.; McCaughan, F.; Mulholland, S.; Arends, M.J.; Ibrahim, A.E.; Dear, P.H. IRS2 is a candidate driver oncogene on 13q34 in colorectal cancer. Int. J. Exp. Pathol. 2013, 94, 203–211.
-
(2013)
Int. J. Exp. Pathol.
, vol.94
, pp. 203-211
-
-
Day, E.1
Poulogiannis, G.2
McCaughan, F.3
Mulholland, S.4
Arends, M.J.5
Ibrahim, A.E.6
Dear, P.H.7
-
61
-
-
84880234110
-
Molecular Basis of Insulin Resistance: The Role of IRS and Foxo1 in the Control of Diabetes Mellitus and Its Complications
-
Guo, S. Molecular Basis of Insulin Resistance: The Role of IRS and Foxo1 in the Control of Diabetes Mellitus and Its Complications. Drug Discov. Today Dis. Mech. 2013, 10, e27–e33. [CrossRef]
-
(2013)
Drug Discov. Today Dis. Mech.
, vol.10
, pp. e27-e33
-
-
Guo, S.1
-
62
-
-
84907867610
-
20 years of leptin: Connecting leptin signaling to biological function
-
Allison, M.B.; Myers, M.G., Jr. 20 years of leptin: Connecting leptin signaling to biological function. J. Endocrinol. 2014, 223, T25–T35. [CrossRef]
-
(2014)
J. Endocrinol.
, vol.223
, pp. T25-T35
-
-
Allison, M.B.1
Myers, M.G.2
-
63
-
-
72249092928
-
Recent advances in understanding leptin signaling and leptin resistance
-
Morris, D.L.; Rui, L.Y. Recent advances in understanding leptin signaling and leptin resistance. Am. J. Physiol. Endocrinol. Metab. 2009, 297, E1247–E1259. [CrossRef]
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.297
, pp. E1247-E1259
-
-
Morris, D.L.1
Rui, L.Y.2
-
64
-
-
43549114292
-
Mechanisms of Leptin Action and Leptin Resistance
-
Myers, M.G.; Cowley, M.A.; Münzberg, H. Mechanisms of Leptin Action and Leptin Resistance. Annu. Rev. Physiol. 2008, 70, 537–556. [CrossRef] [PubMed]
-
(2008)
Annu. Rev. Physiol.
, vol.70
, pp. 537-556
-
-
Myers, M.G.1
Cowley, M.A.2
Münzberg, H.3
-
65
-
-
84855311145
-
Adipocyte-specific deficiency of angiotensinogen decreases plasma angiotensinogen concentration and systolic blood pressure in mice
-
Yiannikouris, F.; Karounos, M.; Charnigo, R.; English, V.L.; Rateri, D.L.; Daugherty, A.; Cassis, L.A. Adipocyte-specific deficiency of angiotensinogen decreases plasma angiotensinogen concentration and systolic blood pressure in mice. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2012, 302, R244–R251. [CrossRef] [PubMed]
-
(2012)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.302
, pp. R244-R251
-
-
Yiannikouris, F.1
Karounos, M.2
Charnigo, R.3
English, V.L.4
Rateri, D.L.5
Daugherty, A.6
Cassis, L.A.7
-
66
-
-
57049155556
-
Hypertension and disrupted blood pressure circadian rhythm in type 2 diabetic db/db mice
-
Su, W.; Guo, Z.; Randall, D.C.; Cassis, L.; Brown, D.R.; Gong, M.C. Hypertension and disrupted blood pressure circadian rhythm in type 2 diabetic db/db mice. Am. J. Physiol. Heart Circ. Physiol. 2008, 295, H1634–H1641. [CrossRef] [PubMed]
-
(2008)
Am. J. Physiol. Heart Circ. Physiol.
, vol.295
, pp. H1634-H1641
-
-
Su, W.1
Guo, Z.2
Randall, D.C.3
Cassis, L.4
Brown, D.R.5
Gong, M.C.6
-
67
-
-
84922393023
-
Novel mechanism of blood pressure regulation by forkhead box class O1-mediated transcriptional control of hepatic angiotensinogen
-
Qi, Y.; Zhang, K.; Wu, Y.; Xu, Z.; Yong, Q.C.; Kumar, R.; Baker, K.M.; Zhu, Q.; Chen, S.; Guo, S. Novel mechanism of blood pressure regulation by forkhead box class O1-mediated transcriptional control of hepatic angiotensinogen. Hypertension 2014, 64, 1131–1140. [CrossRef] [PubMed]
-
(2014)
Hypertension
, vol.64
, pp. 1131-1140
-
-
Qi, Y.1
Zhang, K.2
Wu, Y.3
Xu, Z.4
Yong, Q.C.5
Kumar, R.6
Baker, K.M.7
Zhu, Q.8
Chen, S.9
Guo, S.10
-
68
-
-
84959018825
-
Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies
-
Rani, V.; Deep, G.; Singh, R.K.; Palle, K.; Yadav, U.C. Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies. Life Sci. 2016, 148, 183–193. [CrossRef] [PubMed]
-
(2016)
Life Sci
, vol.148
, pp. 183-193
-
-
Rani, V.1
Deep, G.2
Singh, R.K.3
Palle, K.4
Yadav, U.C.5
-
69
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
Murphy, M.P. How mitochondria produce reactive oxygen species. Biochem. J. 2009, 417, 1–13. [CrossRef] [PubMed]
-
(2009)
Biochem. J
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
70
-
-
79960960007
-
Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways
-
Yecies, J.L.; Zhang, H.H.; Menon, S.; Liu, S.; Yecies, D.; Lipovsky, A.I.; Gorgun, C.; Kwiatkowski, D.J.; Hotamisligil, G.S.; Lee, C.-H.; et al. Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways. Cell Metab. 2011, 14, 280. [CrossRef]
-
(2011)
Cell Metab
, vol.14
, pp. 280
-
-
Yecies, J.L.1
Zhang, H.H.2
Menon, S.3
Liu, S.4
Yecies, D.5
Lipovsky, A.I.6
Gorgun, C.7
Kwiatkowski, D.J.8
Hotamisligil, G.S.9
Lee, C.-H.10
-
71
-
-
83455200244
-
Systemic upregulation of NADPH oxidase in diet-induced obesity in rats
-
Jiang, F.; Lim, H.K.; Morris, M.J.; Prior, L.; Velkoska, E.; Wu, X.; Dusting, G.J. Systemic upregulation of NADPH oxidase in diet-induced obesity in rats. Redox Rep. 2011, 16, 223–229. [CrossRef]
-
(2011)
Redox Rep
, vol.16
, pp. 223-229
-
-
Jiang, F.1
Lim, H.K.2
Morris, M.J.3
Prior, L.4
Velkoska, E.5
Wu, X.6
Dusting, G.J.7
-
72
-
-
39749104251
-
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
-
Yang, X.; Ongusaha, P.P.; Miles, P.D.; Havstad, J.C.; Zhang, F.; So, W.V.; Kudlow, J.E.; Michell, R.H.; Olefsky, J.M.; Field, S.J.; et al. Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance. Nature 2008, 451, 964–969. [CrossRef]
-
(2008)
Nature
, vol.451
, pp. 964-969
-
-
Yang, X.1
Ongusaha, P.P.2
Miles, P.D.3
Havstad, J.C.4
Zhang, F.5
So, W.V.6
Kudlow, J.E.7
Michell, R.H.8
Olefsky, J.M.9
Field, S.J.10
-
73
-
-
79959473762
-
O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver
-
Guinez, C.; Filhoulaud, G.; Rayah-Benhamed, F.; Marmier, S.; Dubuquoy, C.; Dentin, R.; Moldes, M.; Burnol, A.F.; Yang, X.; Lefebvre, T.; et al. O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver. Diabetes 2011, 60, 1399–1413. [CrossRef] [PubMed]
-
(2011)
Diabetes
, vol.60
, pp. 1399-1413
-
-
Guinez, C.1
Filhoulaud, G.2
Rayah-Benhamed, F.3
Marmier, S.4
Dubuquoy, C.5
Dentin, R.6
Moldes, M.7
Burnol, A.F.8
Yang, X.9
Lefebvre, T.10
-
74
-
-
85000788380
-
Impact of Obesity and Metabolic Syndrome on Immunity
-
Andersen, C.J.; Murphy, K.E.; Fernandez, M.L. Impact of Obesity and Metabolic Syndrome on Immunity. Adv. Nutr. 2016, 7, 66–75. [CrossRef] [PubMed]
-
(2016)
Adv. Nutr.
, vol.7
, pp. 66-75
-
-
Andersen, C.J.1
Murphy, K.E.2
Fernandez, M.L.3
-
75
-
-
42449097289
-
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
-
Guilherme, A.; Virbasius, J.V.; Puri, V.; Czech, M.P. Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat. Rev. Mol. Cell Biol. 2008, 9, 367–377. [CrossRef] [PubMed]
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 367-377
-
-
Guilherme, A.1
Virbasius, J.V.2
Puri, V.3
Czech, M.P.4
-
76
-
-
68349137821
-
Normalization of obesity-associated insulin resistance through immunotherapy
-
Winer, S.; Chan, Y.; Paltser, G.; Truong, D.; Tsui, H.; Bahrami, J.; Dorfman, R.; Wang, Y.; Zielenski, J.; Mastronardi, F.; et al. Normalization of obesity-associated insulin resistance through immunotherapy. Nat. Med. 2009, 15, 921–929. [CrossRef] [PubMed]
-
(2009)
Nat. Med.
, vol.15
, pp. 921-929
-
-
Winer, S.1
Chan, Y.2
Paltser, G.3
Truong, D.4
Tsui, H.5
Bahrami, J.6
Dorfman, R.7
Wang, Y.8
Zielenski, J.9
Mastronardi, F.10
-
77
-
-
80655134866
-
Adipose tissue dysregulation in patients with metabolic syndrome
-
Bremer, A.A.; Devaraj, S.; Afify, A.; Jialal, I. Adipose tissue dysregulation in patients with metabolic syndrome. J. Clin. Endocrinol. Metab. 2011, 96, E1782–E1788. [CrossRef] [PubMed]
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
, pp. E1782-E1788
-
-
Bremer, A.A.1
Devaraj, S.2
Afify, A.3
Jialal, I.4
-
78
-
-
84902128282
-
Myeloid cell-specific disruption of Period1 and Period2 exacerbates diet-induced inflammation and insulin resistance
-
Xu, H.; Li, H.; Woo, S.L.; Kim, S.M.; Shende, V.R.; Neuendorff, N.; Guo, X.; Guo, T.; Qi, T.; Pei, Y.; et al. Myeloid cell-specific disruption of Period1 and Period2 exacerbates diet-induced inflammation and insulin resistance. J. Biol. Chem. 2014, 289, 16374–16388. [CrossRef]
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 16374-16388
-
-
Xu, H.1
Li, H.2
Woo, S.L.3
Kim, S.M.4
Shende, V.R.5
Neuendorff, N.6
Guo, X.7
Guo, T.8
Qi, T.9
Pei, Y.10
-
79
-
-
70449122132
-
Foxo1 integrates insulin signaling with mitochondrial function in the liver
-
Cheng, Z.; Guo, S.; Copps, K.; Dong, X.; Kollipara, R.; Rodgers, J.T.; Depinho, R.A.; Puigserver, P.; White, M.F. Foxo1 integrates insulin signaling with mitochondrial function in the liver. Nat. Med. 2009, 15, 1307–1311. [CrossRef] [PubMed]
-
(2009)
Nat. Med.
, vol.15
, pp. 1307-1311
-
-
Cheng, Z.1
Guo, S.2
Copps, K.3
Dong, X.4
Kollipara, R.5
Rodgers, J.T.6
Depinho, R.A.7
Puigserver, P.8
White, M.F.9
-
80
-
-
84904015307
-
Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man
-
Jais, A.; Einwallner, E.; Sharif, O.; Gossens, K.; Lu, T.T.; Soyal, S.M.; Medgyesi, D.; Neureiter, D.; Paier-Pourani, J.; Dalgaard, K.; et al. Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man. Cell 2014, 158, 25–40. [CrossRef]
-
(2014)
Cell
, vol.158
, pp. 25-40
-
-
Jais, A.1
Einwallner, E.2
Sharif, O.3
Gossens, K.4
Lu, T.T.5
Soyal, S.M.6
Medgyesi, D.7
Neureiter, D.8
Paier-Pourani, J.9
Dalgaard, K.10
-
81
-
-
84892167181
-
Toll-like receptor status in obesity and metabolic syndrome: A translational perspective
-
Jialal, I.; Kaur, H.; Devaraj, S. Toll-like receptor status in obesity and metabolic syndrome: A translational perspective. J. Clin. Endocrinol. Metab. 2014, 99, 39–48. [CrossRef]
-
(2014)
J. Clin. Endocrinol. Metab.
, vol.99
, pp. 39-48
-
-
Jialal, I.1
Kaur, H.2
Devaraj, S.3
-
82
-
-
85013409487
-
Inflammation and the Metabolic Syndrome: The Tissue-Specific Functions of NF-kappaB
-
Catrysse, L.; van Loo, G. Inflammation and the Metabolic Syndrome: The Tissue-Specific Functions of NF-kappaB. Trends Cell Biol. 2017, 27, 417–429. [CrossRef]
-
(2017)
Trends Cell Biol
, vol.27
, pp. 417-429
-
-
Catrysse, L.1
van Loo, G.2
-
83
-
-
85020039831
-
Nutritional approaches for managing obesity-associated metabolic diseases
-
Botchlett, R.; Woo, S.L.; Liu, M.; Pei, Y.; Guo, X.; Li, H.; Wu, C. Nutritional approaches for managing obesity-associated metabolic diseases. J. Endocrinol. 2017, 233, R145–R171. [CrossRef] [PubMed]
-
(2017)
J. Endocrinol.
, vol.233
, pp. R145-R171
-
-
Botchlett, R.1
Woo, S.L.2
Liu, M.3
Pei, Y.4
Guo, X.5
Li, H.6
Wu, C.7
-
84
-
-
79952022410
-
Omega-3 Fatty Acids and Inflammatory Processes
-
Calder, P.C. Omega-3 Fatty Acids and Inflammatory Processes. Nutrients 2010, 2, 355–374. [CrossRef]
-
(2010)
Nutrients
, vol.2
, pp. 355-374
-
-
Calder, P.C.1
-
85
-
-
77956165390
-
GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects
-
Oh, D.Y.; Talukdar, S.; Bae, E.J.; Imamura, T.; Morinaga, H.; Fan, W.; Li, P.; Lu, W.J.; Watkins, S.M.; Olefsky, J.M. GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell 2010, 142, 687–698. [CrossRef] [PubMed]
-
(2010)
Cell
, vol.142
, pp. 687-698
-
-
Oh, D.Y.1
Talukdar, S.2
Bae, E.J.3
Imamura, T.4
Morinaga, H.5
Fan, W.6
Li, P.7
Lu, W.J.8
Watkins, S.M.9
Olefsky, J.M.10
-
86
-
-
84867833770
-
Long-chain n-3 PUFAs reduce adipose tissue and systemic inflammation in severely obese nondiabetic patients: A randomized controlled trial
-
Itariu, B.K.; Zeyda, M.; Hochbrugger, E.E.; Neuhofer, A.; Prager, G.; Schindler, K.; Bohdjalian, A.; Mascher, D.; Vangala, S.; Schranz, M.; et al. Long-chain n-3 PUFAs reduce adipose tissue and systemic inflammation in severely obese nondiabetic patients: A randomized controlled trial. Am. J. Clin. Nutr. 2012, 96, 1137–1149. [CrossRef] [PubMed]
-
(2012)
Am. J. Clin. Nutr.
, vol.96
, pp. 1137-1149
-
-
Itariu, B.K.1
Zeyda, M.2
Hochbrugger, E.E.3
Neuhofer, A.4
Prager, G.5
Schindler, K.6
Bohdjalian, A.7
Mascher, D.8
Vangala, S.9
Schranz, M.10
-
87
-
-
84876580724
-
Kern. Omega-3 Fatty Acids Reduce Adipose Tissue Macrophages in Human Subjects With Insulin Resistance
-
Spencer, M.; Finlin, B.S.; Unal, R.; Zhu, B.; Morris, A.J.; Shipp, L.R.; Lee, J.; Walton, R.G.; Adu, A.; Erfani, R.; et al. Kern. Omega-3 Fatty Acids Reduce Adipose Tissue Macrophages in Human Subjects With Insulin Resistance. Diabetes 2013, 62, 1709–1717. [CrossRef] [PubMed]
-
(2013)
Diabetes
, vol.62
, pp. 1709-1717
-
-
Spencer, M.1
Finlin, B.S.2
Unal, R.3
Zhu, B.4
Morris, A.J.5
Shipp, L.R.6
Lee, J.7
Walton, R.G.8
Adu, A.9
Erfani, R.10
-
88
-
-
85018987633
-
Omega-3 polyunsaturated fatty acids ameliorate type 1 diabetes and autoimmunity
-
Bi, X.; Li, F.; Liu, S.; Jin, Y.; Zhang, X.; Yang, T.; Dai, Y.; Li, X.; Zhao, A.Z. omega-3 polyunsaturated fatty acids ameliorate type 1 diabetes and autoimmunity. J. Clin. Investig. 2017, 127, 1757–1771. [CrossRef] [PubMed]
-
(2017)
J. Clin. Investig.
, vol.127
, pp. 1757-1771
-
-
Bi, X.1
Li, F.2
Liu, S.3
Jin, Y.4
Zhang, X.5
Yang, T.6
Dai, Y.7
Li, X.8
Zhao, A.Z.9
-
89
-
-
77955920544
-
Chronobiological aspects of nutrition, metabolic syndrome and obesity
-
Garaulet, M.; Madrid, J.A. Chronobiological aspects of nutrition, metabolic syndrome and obesity. Adv. Drug Deliv. Rev. 2010, 62, 967–978. [CrossRef]
-
(2010)
Adv. Drug Deliv. Rev.
, vol.62
, pp. 967-978
-
-
Garaulet, M.1
Madrid, J.A.2
-
90
-
-
20844461135
-
Obesity and metabolic syndrome in circadian Clock mutant mice
-
Turek, F.W.; Joshu, C.; Kohsaka, A.; Lin, E.; Ivanova, G.; McDearmon, E.; Laposky, A.; Losee-Olson, S.; Easton, A.; Jensen, D.R.; et al. Obesity and metabolic syndrome in circadian Clock mutant mice. Science 2005, 308, 1043–1045. [CrossRef]
-
(2005)
Science
, vol.308
, pp. 1043-1045
-
-
Turek, F.W.1
Joshu, C.2
Kohsaka, A.3
Lin, E.4
Ivanova, G.5
McDearmon, E.6
Laposky, A.7
Losee-Olson, S.8
Easton, A.9
Jensen, D.R.10
-
91
-
-
84902211674
-
Insulin-FOXO3 Signaling Modulates Circadian Rhythms via Regulation of Clock Transcription
-
Chaves, I.; van der Horst, G.T.J.; Schellevis, R.; Nijman, R.M.; Koerkamp, M.G.; Holstege, F.C.P.; Smidt, M.P.; Hoekman, M.F.M. Insulin-FOXO3 Signaling Modulates Circadian Rhythms via Regulation of Clock Transcription. Curr. Biol. 2014, 24, 1248–1255. [CrossRef]
-
(2014)
Curr. Biol.
, vol.24
, pp. 1248-1255
-
-
Chaves, I.1
van der Horst, G.T.J.2
Schellevis, R.3
Nijman, R.M.4
Koerkamp, M.G.5
Holstege, F.C.P.6
Smidt, M.P.7
Hoekman, M.F.M.8
-
92
-
-
14044264801
-
BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis
-
Rudic, R.D.; McNamara, P.; Curtis, A.M.; Boston, R.C.; Panda, S.; Hogenesch, J.B.; FitzGerald, G.A. BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis. PLoS Biol. 2004, 2, 1893–1899. [CrossRef]
-
(2004)
Plos Biol
, vol.2
, pp. 1893-1899
-
-
Rudic, R.D.1
McNamara, P.2
Curtis, A.M.3
Boston, R.C.4
Panda, S.5
Hogenesch, J.B.6
Fitzgerald, G.A.7
-
93
-
-
84875210996
-
Circadian Disruption Leads to Insulin Resistance and Obesity
-
Shi, S.-Q.; Ansari, T.S.; McGuinness, O.P.; Wasserman, D.H.; Johnson, C.H. Circadian Disruption Leads to Insulin Resistance and Obesity. Curr. Biol. 2013, 23, 372–381. [CrossRef] [PubMed]
-
(2013)
Curr. Biol.
, vol.23
, pp. 372-381
-
-
Shi, S.-Q.1
Ansari, T.S.2
McGuinness, O.P.3
Wasserman, D.H.4
Johnson, C.H.5
-
94
-
-
85052075417
-
Role of the Circadian Clock in the Metabolic Syndrome and Nonalcoholic Fatty Liver Disease
-
Shetty, A.; Hsu, J.W.; Manka, P.P.; Syn, W.K. Role of the Circadian Clock in the Metabolic Syndrome and Nonalcoholic Fatty Liver Disease. Dig. Dis. Sci. 2018, 63, 3187–3206. [CrossRef] [PubMed]
-
(2018)
Dig. Dis. Sci.
, vol.63
, pp. 3187-3206
-
-
Shetty, A.1
Hsu, J.W.2
Manka, P.P.3
Syn, W.K.4
-
95
-
-
84902320509
-
Circadian control of glucose metabolism
-
Kalsbeek, A.; la Fleur, S.; Fliers, E. Circadian control of glucose metabolism. Mol. Metab. 2014, 3, 372–383. [CrossRef] [PubMed]
-
(2014)
Mol. Metab.
, vol.3
, pp. 372-383
-
-
Kalsbeek, A.1
la Fleur, S.2
Fliers, E.3
-
96
-
-
52149109334
-
The genetics of mammalian circadian order and disorder: Implications for physiology and disease
-
Takahashi, J.S.; Hong, H.-K.; Ko, C.H.; McDearmon, E.L. The genetics of mammalian circadian order and disorder: Implications for physiology and disease. Nat. Rev. Genet. 2008, 9, 764. [CrossRef] [PubMed]
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 764
-
-
Takahashi, J.S.1
Hong, H.-K.2
Ko, C.H.3
McDearmon, E.L.4
-
97
-
-
84894590704
-
Reprogramming of the Circadian Clock by Nutritional Challenge
-
Eckel-Mahan, K.L.; Patel, V.R.; de Mateo, S.; Orozco-Solis, R.; Ceglia, N.J.; Sahar, S.; Dilag-Penilla, S.A.; Dyar, K.A.; Baldi, P.; Sassone-Corsi, P. Reprogramming of the Circadian Clock by Nutritional Challenge. Cell 2013, 155, 1464–1478. [CrossRef] [PubMed]
-
(2013)
Cell
, vol.155
, pp. 1464-1478
-
-
Eckel-Mahan, K.L.1
Patel, V.R.2
de Mateo, S.3
Orozco-Solis, R.4
Ceglia, N.J.5
Sahar, S.6
Dilag-Penilla, S.A.7
Dyar, K.A.8
Baldi, P.9
Sassone-Corsi, P.10
-
98
-
-
57649207949
-
High-fat feeding alters the clock synchronization to light
-
Mendoza, J.; Pevet, P.; Challet, E. High-fat feeding alters the clock synchronization to light. J. Physiol. 2008, 586, 5901–5910. [CrossRef] [PubMed]
-
(2008)
J. Physiol.
, vol.586
, pp. 5901-5910
-
-
Mendoza, J.1
Pevet, P.2
Challet, E.3
-
99
-
-
35548930677
-
High-Fat Diet Disrupts Behavioral and Molecular Circadian Rhythms in Mice
-
Kohsaka, A.; Laposky, A.D.; Ramsey, K.M.; Estrada, C.; Joshu, C.; Kobayashi, Y.; Turek, F.W.; Bass, J. High-Fat Diet Disrupts Behavioral and Molecular Circadian Rhythms in Mice. Cell Metab. 2007, 6, 414–421. [CrossRef]
-
(2007)
Cell Metab
, vol.6
, pp. 414-421
-
-
Kohsaka, A.1
Laposky, A.D.2
Ramsey, K.M.3
Estrada, C.4
Joshu, C.5
Kobayashi, Y.6
Turek, F.W.7
Bass, J.8
-
100
-
-
0036487233
-
Alterations of the circadian clock in the heart by streptozotocin-induced diabetes
-
Young, M.E.; Wilson, C.R.; Razeghi, P.; Guthrie, P.H.; Taegtmeyer, H. Alterations of the circadian clock in the heart by streptozotocin-induced diabetes. J. Mol. Cell. Cardiol. 2002, 34, 223–231. [CrossRef]
-
(2002)
J. Mol. Cell. Cardiol.
, vol.34
, pp. 223-231
-
-
Young, M.E.1
Wilson, C.R.2
Razeghi, P.3
Guthrie, P.H.4
Taegtmeyer, H.5
-
101
-
-
84942898373
-
Greenlandic Inuit show genetic signatures of diet and climate adaptation
-
Fumagalli, M.; Moltke, I.; Grarup, N.; Racimo, F.; Bjerregaard, P.; Jorgensen, M.E.; Korneliussen, T.S.; Gerbault, P.; Skotte, L.; Linneberg, A.; et al. Greenlandic Inuit show genetic signatures of diet and climate adaptation. Science 2015, 349, 1343–1347. [CrossRef]
-
(2015)
Science
, vol.349
, pp. 1343-1347
-
-
Fumagalli, M.1
Moltke, I.2
Grarup, N.3
Racimo, F.4
Bjerregaard, P.5
Jorgensen, M.E.6
Korneliussen, T.S.7
Gerbault, P.8
Skotte, L.9
Linneberg, A.10
-
102
-
-
84891787628
-
Circulating 25-hydroxyvitamin D, IRS1 variant rs2943641, and insulin resistance: Replication of a gene-nutrient interaction in 4 populations of different ancestries
-
Zheng, J.S.; Parnell, L.D.; Smith, C.E.; Lee, Y.C.; Jamal-Allial, A.; Ma, Y.; Li, D.; Tucker, K.L.; Ordovas, J.M.; Lai, C.Q. Circulating 25-hydroxyvitamin D, IRS1 variant rs2943641, and insulin resistance: Replication of a gene-nutrient interaction in 4 populations of different ancestries. Clin. Chem. 2014, 60, 186–196. [CrossRef]
-
(2014)
Clin. Chem.
, vol.60
, pp. 186-196
-
-
Zheng, J.S.1
Parnell, L.D.2
Smith, C.E.3
Lee, Y.C.4
Jamal-Allial, A.5
Ma, Y.6
Li, D.7
Tucker, K.L.8
Ordovas, J.M.9
Lai, C.Q.10
-
103
-
-
0035896580
-
Insulin suppresses transactivation by CAAT/enhancer-binding proteins beta (C/EBPbeta). Signaling to p300/CREB-binding protein by protein kinase B disrupts interaction with the major activation domain of C/EBPbeta
-
Guo, S.; Cichy, S.B.; He, X.; Yang, Q.; Ragland, M.; Ghosh, A.K.; Johnson, P.F.; Unterman, T.G. Insulin suppresses transactivation by CAAT/enhancer-binding proteins beta (C/EBPbeta). Signaling to p300/CREB-binding protein by protein kinase B disrupts interaction with the major activation domain of C/EBPbeta. J. Biol. Chem. 2001, 276, 8516–8523. [CrossRef] [PubMed]
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 8516-8523
-
-
Guo, S.1
Cichy, S.B.2
He, X.3
Yang, Q.4
Ragland, M.5
Ghosh, A.K.6
Johnson, P.F.7
Unterman, T.G.8
-
104
-
-
85026216613
-
Endotoxemia-mediated activation of acetyltransferase P300 impairs insulin signaling in obesity
-
Cao, J.; Peng, J.; An, H.; He, Q.; Boronina, T.; Guo, S.; White, M.F.; Cole, P.A.; He, L. Endotoxemia-mediated activation of acetyltransferase P300 impairs insulin signaling in obesity. Nat. Commun. 2017, 8, 131. [CrossRef] [PubMed]
-
(2017)
Nat. Commun.
, vol.8
, pp. 131
-
-
Cao, J.1
Peng, J.2
An, H.3
He, Q.4
Boronina, T.5
Guo, S.6
White, M.F.7
Cole, P.A.8
He, L.9
-
105
-
-
84992426192
-
The microbial epigenome in metabolic syndrome
-
Remely, M.; Haslberger, A.G. The microbial epigenome in metabolic syndrome. Mol. Asp. Med. 2017, 54, 71–77. [CrossRef] [PubMed]
-
(2017)
Mol. Asp. Med.
, vol.54
, pp. 71-77
-
-
Remely, M.1
Haslberger, A.G.2
-
106
-
-
85010931720
-
High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive Mice
-
Marques, F.Z.; Nelson, E.; Chu, P.Y.; Horlock, D.; Fiedler, A.; Ziemann, M.; Tan, J.K.; Kuruppu, S.; Rajapakse, N.W.; El-Osta, A.; et al. High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive Mice. Circulation 2017, 135, 964–977. [CrossRef] [PubMed]
-
(2017)
Circulation
, vol.135
, pp. 964-977
-
-
Marques, F.Z.1
Nelson, E.2
Chu, P.Y.3
Horlock, D.4
Fiedler, A.5
Ziemann, M.6
Tan, J.K.7
Kuruppu, S.8
Rajapakse, N.W.9
El-Osta, A.10
-
107
-
-
84943190838
-
Lack of soluble fiber drives diet-induced adiposity in mice
-
Chassaing, B.; Miles-Brown, J.; Pellizzon, M.; Ulman, E.; Ricci, M.; Zhang, L.; Patterson, A.D.; Vijay-Kumar, M.; Gewirtz, A.T. Lack of soluble fiber drives diet-induced adiposity in mice. Am. J. Physiol. Gastrointest. Liver Physiol. 2015, 309, G528–G541. [CrossRef] [PubMed]
-
(2015)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.309
, pp. G528-G541
-
-
Chassaing, B.1
Miles-Brown, J.2
Pellizzon, M.3
Ulman, E.4
Ricci, M.5
Zhang, L.6
Patterson, A.D.7
Vijay-Kumar, M.8
Gewirtz, A.T.9
-
108
-
-
84875753000
-
Dietary fat content and fiber type modulate hind gut microbial community and metabolic markers in the pig
-
Yan, H.; Potu, R.; Lu, H.; Vezzoni de Almeida, V.; Stewart, T.; Ragland, D.; Armstrong, A.; Adeola, O.; Nakatsu, C.H.; Ajuwon, K.M. Dietary fat content and fiber type modulate hind gut microbial community and metabolic markers in the pig. PLoS ONE 2013, 8, e59581. [CrossRef] [PubMed]
-
(2013)
Plos ONE
, vol.8
-
-
Yan, H.1
Potu, R.2
Lu, H.3
Vezzoni de Almeida, V.4
Stewart, T.5
Ragland, D.6
Armstrong, A.7
Adeola, O.8
Nakatsu, C.H.9
Ajuwon, K.M.10
-
109
-
-
84927694747
-
Modulation of gut microbiota during probiotic-mediated attenuation of metabolic syndrome in high fat diet-fed mice
-
Wang, J.; Tang, H.; Zhang, C.; Zhao, Y.; Derrien, M.; Rocher, E.; van-Hylckama Vlieg, J.E.; Strissel, K.; Zhao, L.; Obin, M.; et al. Modulation of gut microbiota during probiotic-mediated attenuation of metabolic syndrome in high fat diet-fed mice. ISME J 2015, 9, 1–15. [CrossRef]
-
(2015)
ISME J
, vol.9
, pp. 1-15
-
-
Wang, J.1
Tang, H.2
Zhang, C.3
Zhao, Y.4
Derrien, M.5
Rocher, E.6
Van-Hylckama Vlieg, J.E.7
Strissel, K.8
Zhao, L.9
Obin, M.10
-
110
-
-
84923593959
-
Probiotic supplementation prevents high-fat, overfeeding-induced insulin resistance in human subjects
-
Hulston, C.J.; Churnside, A.A.; Venables, M.C. Probiotic supplementation prevents high-fat, overfeeding-induced insulin resistance in human subjects. Br. J. Nutr. 2015, 113, 596–602. [CrossRef]
-
(2015)
Br. J. Nutr.
, vol.113
, pp. 596-602
-
-
Hulston, C.J.1
Churnside, A.A.2
Venables, M.C.3
-
111
-
-
70350043072
-
The Improvement of Hypertension by Probiotics: Effects on Cholesterol, Diabetes, Renin, and Phytoestrogens
-
Lye, H.S.; Kuan, C.Y.; Ewe, J.A.; Fung, W.Y.; Liong, M.T. The Improvement of Hypertension by Probiotics: Effects on Cholesterol, Diabetes, Renin, and Phytoestrogens. Int. J. Mol. Sci. 2009, 10, 3755–3775. [CrossRef]
-
(2009)
Int. J. Mol. Sci.
, vol.10
, pp. 3755-3775
-
-
Lye, H.S.1
Kuan, C.Y.2
Ewe, J.A.3
Fung, W.Y.4
Liong, M.T.5
-
112
-
-
84941248927
-
Excessive caloric intake acutely causes oxidative stress, GLUT4 carbonylation, and insulin resistance in healthy men
-
Guenther Boden, C.H.; Barrero, C.A.; Stein, T.P.; Chen, X.; Cheung, P.; Fecchio, C.; Koller, S.; Merali, S. Excessive caloric intake acutely causes oxidative stress, GLUT4 carbonylation, and insulin resistance in healthy men. Sci. Transl. Med. 2015, 7, 304re307.
-
(2015)
Sci. Transl. Med.
, vol.7
-
-
Guenther Boden, C.H.1
Barrero, C.A.2
Stein, T.P.3
Chen, X.4
Cheung, P.5
Fecchio, C.6
Koller, S.7
Merali, S.8
-
113
-
-
84990055879
-
High intake of regular-fat cheese compared with reduced-fat cheese does not affect LDL cholesterol or risk markers of the metabolic syndrome: A randomized controlled trial
-
Raziani, F.; Tholstrup, T.; Kristensen, M.D.; Svanegaard, M.L.; Ritz, C.; Astrup, A.; Raben, A. High intake of regular-fat cheese compared with reduced-fat cheese does not affect LDL cholesterol or risk markers of the metabolic syndrome: A randomized controlled trial. Am. J. Clin. Nutr. 2016, 104, 973–981. [CrossRef] [PubMed]
-
(2016)
Am. J. Clin. Nutr.
, vol.104
, pp. 973-981
-
-
Raziani, F.1
Tholstrup, T.2
Kristensen, M.D.3
Svanegaard, M.L.4
Ritz, C.5
Astrup, A.6
Raben, A.7
-
114
-
-
84940998323
-
Effect of a high intake of cheese on cholesterol and metabolic syndrome: Results of a randomized trial
-
Nilsen, R.; Hostmark, A.T.; Haug, A.; Skeie, S. Effect of a high intake of cheese on cholesterol and metabolic syndrome: Results of a randomized trial. Food Nutr. Res. 2015, 59, 27651. [CrossRef] [PubMed]
-
(2015)
Food Nutr. Res.
, vol.59
-
-
Nilsen, R.1
Hostmark, A.T.2
Haug, A.3
Skeie, S.4
-
115
-
-
84941703082
-
Diets with high-fat cheese, high-fat meat, or carbohydrate on cardiovascular risk markers in overweight postmenopausal women: A randomized crossover trial
-
Thorning, T.K.; Raziani, F.; Bendsen, N.T.; Astrup, A.; Tholstrup, T.; Raben, A. Diets with high-fat cheese, high-fat meat, or carbohydrate on cardiovascular risk markers in overweight postmenopausal women: A randomized crossover trial. Am. J. Clin. Nutr. 2015, 102, 573–581. [CrossRef] [PubMed]
-
(2015)
Am. J. Clin. Nutr.
, vol.102
, pp. 573-581
-
-
Thorning, T.K.1
Raziani, F.2
Bendsen, N.T.3
Astrup, A.4
Tholstrup, T.5
Raben, A.6
-
116
-
-
85014126962
-
Fasting-Mimicking Diet Promotes Ngn3-Driven beta-Cell Regeneration to Reverse Diabetes
-
Cheng, C.W.; Villani, V.; Buono, R.; Wei, M.; Kumar, S.; Yilmaz, O.H.; Cohen, P.; Sneddon, J.B.; Perin, L.; Longo, V.D. Fasting-Mimicking Diet Promotes Ngn3-Driven beta-Cell Regeneration to Reverse Diabetes. Cell 2017, 168, 775–788. [CrossRef] [PubMed]
-
(2017)
Cell
, vol.168
, pp. 775-788
-
-
Cheng, C.W.1
Villani, V.2
Buono, R.3
Wei, M.4
Kumar, S.5
Yilmaz, O.H.6
Cohen, P.7
Sneddon, J.B.8
Perin, L.9
Longo, V.D.10
-
117
-
-
84942615136
-
Saturated Fats Compared With Unsaturated Fats and Sources of Carbohydrates in Relation to Risk of Coronary Heart Disease: A Prospective Cohort Study
-
Li, Y.; Hruby, A.; Bernstein, A.M.; Ley, S.H.; Wang, D.D.; Chiuve, S.E.; Sampson, L.; Rexrode, K.M.; Rimm, E.B.; Willett, W.C.; et al. Saturated Fats Compared With Unsaturated Fats and Sources of Carbohydrates in Relation to Risk of Coronary Heart Disease: A Prospective Cohort Study. J. Am. Coll. Cardiol. 2015, 66, 1538–1548. [CrossRef] [PubMed]
-
(2015)
J. Am. Coll. Cardiol.
, vol.66
, pp. 1538-1548
-
-
Li, Y.1
Hruby, A.2
Bernstein, A.M.3
Ley, S.H.4
Wang, D.D.5
Chiuve, S.E.6
Sampson, L.7
Rexrode, K.M.8
Rimm, E.B.9
Willett, W.C.10
-
118
-
-
85020532561
-
Dietary Fats and Cardiovascular Disease: A Presidential Advisory From the American Heart Association
-
Sacks, F.M.; Lichtenstein, A.H.; Wu, J.H.Y.; Appel, L.J.; Creager, M.A.; Kris-Etherton, P.M.; Miller, M.; Rimm, E.B.; Rudel, L.L.; Robinson, J.G.; et al. Dietary Fats and Cardiovascular Disease: A Presidential Advisory From the American Heart Association. Circulation 2017, 136, e1–e23. [CrossRef] [PubMed]
-
(2017)
Circulation
, vol.136
-
-
Sacks, F.M.1
Lichtenstein, A.H.2
Wu, J.H.Y.3
Appel, L.J.4
Creager, M.A.5
Kris-Etherton, P.M.6
Miller, M.7
Rimm, E.B.8
Rudel, L.L.9
Robinson, J.G.10
-
119
-
-
84934921383
-
Monounsaturated Fatty Acid–Enriched High-Fat Diets Impede Adipose NLRP3 Inflammasome–Mediated IL-1β Secretion and Insulin Resistance Despite Obesity
-
Finucane, O.M.; Lyons, C.L.; Murphy, A.M.; Reynolds, C.M.; Klinger, R.; Healy, N.P.; Cooke, A.A.; Coll, R.C.; McAllan, L.; Nilaweera, K.N.; et al. Monounsaturated Fatty Acid–Enriched High-Fat Diets Impede Adipose NLRP3 Inflammasome–Mediated IL-1β Secretion and Insulin Resistance Despite Obesity. Diabetes 2015, 64, 2116–2128. [CrossRef]
-
(2015)
Diabetes
, vol.64
, pp. 2116-2128
-
-
Finucane, O.M.1
Lyons, C.L.2
Murphy, A.M.3
Reynolds, C.M.4
Klinger, R.5
Healy, N.P.6
Cooke, A.A.7
Coll, R.C.8
McAllan, L.9
Nilaweera, K.N.10
-
120
-
-
84927173996
-
Branched-chain amino acids in metabolic signalling and insulin resistance
-
Lynch, C.J.; Adams, S.H. Branched-chain amino acids in metabolic signalling and insulin resistance. Nat. Rev. Endocrinol. 2014, 10, 723–736. [CrossRef]
-
(2014)
Nat. Rev. Endocrinol.
, vol.10
, pp. 723-736
-
-
Lynch, C.J.1
Adams, S.H.2
-
121
-
-
84861445589
-
Procyanidins Improve some Disrupted Glucose Homoeostatic Situations: An Analysis of Doses and Treatments According to Different Animal Models
-
Pinent, M.; Cedo, L.; Montagut, G.; Blay, M.; Ardevol, A. Procyanidins Improve some Disrupted Glucose Homoeostatic Situations: An Analysis of Doses and Treatments According to Different Animal Models. Crit. Rev. Food Sci. Nutr. 2012, 52, 569–584. [CrossRef]
-
(2012)
Crit. Rev. Food Sci. Nutr.
, vol.52
, pp. 569-584
-
-
Pinent, M.1
Cedo, L.2
Montagut, G.3
Blay, M.4
Ardevol, A.5
-
122
-
-
84885868900
-
Recent advances in understanding the anti-diabetic actions of dietary flavonoids
-
Babu, P.V.A.; Liu, D.M.; Gilbert, E.R. Recent advances in understanding the anti-diabetic actions of dietary flavonoids. J. Nutr. Biochem. 2013, 24, 1777–1789. [CrossRef]
-
(2013)
J. Nutr. Biochem.
, vol.24
, pp. 1777-1789
-
-
Babu, P.V.A.1
Liu, D.M.2
Gilbert, E.R.3
-
123
-
-
85000405991
-
A-type procyanidins from litchi pericarp ameliorate hyperglycaemia by regulating hepatic and muscle glucose metabolism in streptozotocin (STZ)-induced diabetic mice fed with high fat diet
-
Li, X.; Sui, Y.; Li, S.; Xie, B.; Sun, Z. A-type procyanidins from litchi pericarp ameliorate hyperglycaemia by regulating hepatic and muscle glucose metabolism in streptozotocin (STZ)-induced diabetic mice fed with high fat diet. J. Funct. Foods 2016, 27, 711–722. [CrossRef]
-
(2016)
J. Funct. Foods
, vol.27
, pp. 711-722
-
-
Li, X.1
Sui, Y.2
Li, S.3
Xie, B.4
Sun, Z.5
-
124
-
-
85053835107
-
(-)-Epigallocatechin-3-Gallate (EGCG) inhibits starch digestion and improves glucose homeostasis through direct or indirect activation of PXR/CAR-mediated phase II metabolism in diabetic mice
-
Li, X.; Li, S.; Chen, M.; Wang, J.; Xie, B.; Sun, Z. (-)-Epigallocatechin-3-Gallate (EGCG) inhibits starch digestion and improves glucose homeostasis through direct or indirect activation of PXR/CAR-mediated phase II metabolism in diabetic mice. Food Funct. 2018, 9, 4651–4663. [CrossRef] [PubMed]
-
(2018)
Food Funct
, vol.9
, pp. 4651-4663
-
-
Li, X.1
Li, S.2
Chen, M.3
Wang, J.4
Xie, B.5
Sun, Z.6
-
125
-
-
74349097440
-
Hypolipidemic effects of proanthocyanidins and their underlying biochemical and molecular mechanisms
-
Blade, C.; Arola, L.; Salvado, M.J. Hypolipidemic effects of proanthocyanidins and their underlying biochemical and molecular mechanisms. Mol. Nutr. Food Res. 2010, 54, 37–59. [CrossRef] [PubMed]
-
(2010)
Mol. Nutr. Food Res.
, vol.54
, pp. 37-59
-
-
Blade, C.1
Arola, L.2
Salvado, M.J.3
-
126
-
-
77951934925
-
Impact of Dietary Polyphenols on Carbohydrate Metabolism
-
Hanhineva, K.; Törrönen, R.; Bondia-Pons, I.; Pekkinen, J.; Kolehmainen, M.; Mykkänen, H.; Poutanen, K. Impact of Dietary Polyphenols on Carbohydrate Metabolism. Int. J. Mol. Sci. 2010, 11, 1365–1402. [CrossRef] [PubMed]
-
(2010)
Int. J. Mol. Sci.
, vol.11
, pp. 1365-1402
-
-
Hanhineva, K.1
Törrönen, R.2
Bondia-Pons, I.3
Pekkinen, J.4
Kolehmainen, M.5
Mykkänen, H.6
Poutanen, K.7
-
127
-
-
84887558484
-
High selenium impairs hepatic insulin sensitivity through opposite regulation of ROS
-
Wang, X.; Zhang, W.; Chen, H.; Liao, N.; Wang, Z.; Zhang, X.; Hai, C. High selenium impairs hepatic insulin sensitivity through opposite regulation of ROS. Toxicol. Lett. 2014, 224, 16–23. [CrossRef] [PubMed]
-
(2014)
Toxicol. Lett.
, vol.224
, pp. 16-23
-
-
Wang, X.1
Zhang, W.2
Chen, H.3
Liao, N.4
Wang, Z.5
Zhang, X.6
Hai, C.7
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