Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes

Cell

Volumn 168, Issue 5, 2017, Pages 775-788.e12

  Cheng, Chia Wei ^a,e   Villani, Valentina ^a   Buono, Roberta ^a,d   Wei, Min ^a   Kumar, Sanjeev ^c   Yilmaz, Omer H ^e   Cohen, Pinchas ^a   Sneddon, Julie B ^b   Perin, Laura ^a   Longo, Valter D ^a,c,d  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOKINE; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; NEUROGENIN 3; SOMATOMEDIN C; TRANSCRIPTION FACTOR PDX 1; TRANSCRIPTION FACTOR SOX17; TRANSCRIPTION FACTOR SOX2; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; NERVE PROTEIN; NEUROG3 PROTEIN, MOUSE; TRANSCRIPTOME;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE; CELL DEDIFFERENTIATION; CELL REGENERATION; CONTROLLED STUDY; DIET RESTRICTION; GENE EXPRESSION; GLUCOSE HOMEOSTASIS; HUMORAL IMMUNE DEFICIENCY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; INTRACELLULAR SIGNALING; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS CELL; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; ANIMAL; CYTOLOGY; DIET; DIET THERAPY; GENETICS; GLUCOSE TOLERANCE TEST; HUMAN; IN VITRO STUDY; METABOLISM; PANCREAS; SIGNAL TRANSDUCTION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; DIET; FASTING; GLUCOSE TOLERANCE TEST; HUMANS; IN VITRO TECHNIQUES; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MICE; NERVE TISSUE PROTEINS; PANCREAS; SIGNAL TRANSDUCTION; TRANSCRIPTOME;

EID: 85014126962     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.01.040     Document Type: Article

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