Greenlandic Inuit show genetic signatures of diet and climate adaptation

Science

Volumn 349, Issue 6254, 2015, Pages 1343-1347

  Fumagalli, Matteo ^a,b   Moltke, Ida ^c   Grarup, Niels ^d   Racimo, Fernando ^b   Bjerregaard, Peter ^e,f   Jørgensen, Marit E ^e,g   Korneliussen, Thorfinn S ^h   Gerbault, Pascale ^a   Skotte, Line ^c   Linneberg, Allan ^i,j,k   Christensen, Cramer ^l   Brandslund, Ivan ^l,m   Jørgensen, Torben ^i,k,n   Huerta Sánchez, Emilia ^o   Schmidt, Erik B ^n,p   Pedersen, Oluf ^d   Hansen, Torben ^d   Albrechtsen, Anders ^c   Nielsen, Rasmus ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d Capital Region   (Denmark)

^e UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^f UNIVERSITY OF GREENLAND   (Greenland)

^g STENO DIABETES CENTER   (Denmark)

^h UNIVERSITY OF COPENHAGEN   (Denmark)

ⁱ Unit for Psychotherapy Education and Research   (Denmark)

^j Rigshospitalet   (Denmark)

^k UNIVERSITY OF COPENHAGEN   (Denmark)

^l LILLEBAELT HOSPITAL   (Denmark)

^m UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

ⁿ AALBORG UNIVERSITY   (Denmark)

^o UNIVERSITY OF CALIFORNIA   (United States)

^p AALBORG UNIVERSITY HOSPITAL   (Denmark)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DESATURASE; ACYL COENZYME A DESATURASE 1; GROWTH HORMONE; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OMEGA 3 FATTY ACID; POLYUNSATURATED FATTY ACID; MEMBRANE LIPID;

ALLELE; CLIMATE CHANGE; DIET; FATTY ACID; GENETIC STRUCTURE; GENOME; HEIGHT; HORMONE; INDIGENOUS POPULATION; LIPID; LOW TEMPERATURE; PHYSIOLOGICAL RESPONSE; PROTEIN; WEIGHT;

ALLELE; ARCTIC; ARTICLE; BODY HEIGHT; BODY MASS; BODY WEIGHT; CHROMOSOME 1; CLIMATE; DIET; EFFECT SIZE; EUROPEAN; EVOLUTIONARY ADAPTATION; FAT INTAKE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GREENLAND; HUMAN; HUMAN GENOME; INSULIN BLOOD LEVEL; INUIT; LIPID COMPOSITION; LIPID DIET; OPEN READING FRAME; PHENOTYPE; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROTEIN DIET; SINGLE NUCLEOTIDE POLYMORPHISM; ACCLIMATIZATION; CHROMOSOME 11; FEMALE; GENE LOCUS; GENETIC SELECTION; GENETICS; MALE;

ARCTIC; EUROPE; GREENLAND;

ACCLIMATIZATION; ALLELES; ARCTIC REGIONS; BODY HEIGHT; BODY WEIGHT; CHROMOSOMES, HUMAN, PAIR 11; CLIMATE; DIET, HIGH-FAT; FATTY ACIDS, OMEGA-3; FEMALE; GENETIC LOCI; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; GREENLAND; HUMANS; INUITS; LINKAGE DISEQUILIBRIUM; MALE; MEMBRANE LIPIDS; POLYMORPHISM, SINGLE NUCLEOTIDE; SELECTION, GENETIC;

EID: 84942898373     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aab2319     Document Type: Article

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