Mortality risk in older men associated with changes in weight, lean mass, and fat mass

Journal of the American Geriatrics Society

Volumn 59, Issue 2, 2011, Pages 233-240

  Lee, Christine G ^a   Boyko, Edward J ^c   Nielson, Carrie M ^b   Stefanick, Marcia L ^d   Bauer, Douglas C ^e   Hoffman, Andrew R ^d   Dam, Thuy Tien L ^f   Lapidus, Jodi A ^b   Cawthon, Peggy Mannen ^f   Ensrud, Kristine E ^g   Orwoll, Eric S ^a,h  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f NewYork Presbyterian Hospital   (United States)

^g CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

^h VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

body composition; fat mass; lean mass; mortality; older men

Indexed keywords

AGED; ARTICLE; BODY COMPOSITION; BODY FAT; BODY MASS; COHORT ANALYSIS; DEATH CERTIFICATE; DUAL ENERGY X RAY ABSORPTIOMETRY; HEALTH STATUS; HUMAN; LEAN BODY WEIGHT; LIFESTYLE; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MORTALITY; OBESITY; PROPORTIONAL HAZARDS MODEL; SELF REPORT; WEIGHT GAIN; WEIGHT REDUCTION;

ABSORPTIOMETRY, PHOTON; ADIPOSITY; AGED; AGED, 80 AND OVER; BODY MASS INDEX; BODY WEIGHT; CAUSE OF DEATH; FOLLOW-UP STUDIES; HUMANS; MALE; OSTEOPOROTIC FRACTURES; OVERWEIGHT; PROGNOSIS; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL RATE; UNITED STATES; WEIGHT GAIN; WEIGHT LOSS;

EID: 79951591201     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/j.1532-5415.2010.03245.x     Document Type: Article

References (48)

1. Rissanen A, Heliovaara M, Knekt P, et al,. Weight and mortality in Finnish men. J Clin Epidemiol 1989; 42: 781-789. (Pubitemid 19213125)
2. Lee IM, Manson JE, Hennekens CH, et al,. Body weight and mortality. A 27-year follow-up of middle-aged men. JAMA 1993; 270: 2823-2828. (Pubitemid 23361645)
3. Manson JE, Willett WC, Stampfer MJ, et al,. Body weight and mortality among women. N Engl J Med 1995; 333: 677-685.
4. Janssen I, Mark AE., Elevated body mass index and mortality risk in the elderly. Obes Rev 2007; 8: 41-59. (Pubitemid 44952834)
5. Kuk JL, Ardern CI., Influence of age on the association between various measures of obesity and all-cause mortality. J Am Geriatr Soc 2009; 57: 2077-2084.
6. Grabowski DC, Ellis JE., High body mass index does not predict mortality in older people: Analysis of the Longitudinal Study of Aging. J Am Geriatr Soc 2001; 49: 968-979. (Pubitemid 32743634)
7. Heiat A, Vaccarino V, Krumholz HM., An evidence-based assessment of federal guidelines for overweight and obesity as they apply to elderly persons. Arch Intern Med 2001; 161: 1194-1203. (Pubitemid 32691516)
8. Woo J, Ho SC, Sham A., Longitudinal changes in body mass index and body composition over 3 years and relationship to health outcomes in Hong Kong Chinese age 70 and older. J Am Geriatr Soc 2001; 49: 737-746. (Pubitemid 32652466)
9. Goldstein DJ., Beneficial health effects of modest weight loss. Int J Obes Relat Metab Disord 1992; 16: 397-415.
10. Wallace JI, Schwartz RS, LaCroix AZ, et al,. Involuntary weight loss in older outpatients: Incidence and clinical significance. J Am Geriatr Soc 1995; 43: 329-337.
11. Newman AB, Yanez D, Harris T, et al,. Weight change in old age and its association with mortality. J Am Geriatr Soc 2001; 49: 1309-1318. (Pubitemid 33015207)
12. Howard BV, Manson JE, Stefanick ML, et al,. Low-fat dietary pattern and weight change over 7 years: The Women's Health Initiative Dietary Modification Trial. JAMA 2006; 295: 39-49. (Pubitemid 43042688)
13. Droyvold WB, Nilsen TI, Kruger O, et al,. Change in height, weight and body mass index: Longitudinal data from the HUNT Study in Norway. Int J Obes (Lond) 2006; 30: 935-939. (Pubitemid 43801193)
14. Fantin F, Di Francesco V, Fontana G, et al,. Longitudinal body composition changes in old men and women: Interrelationships with worsening disability. J Gerontol A Biol Sci Med Sci 2007; 62: 1375-1381. (Pubitemid 351158365)
15. Newman AB, Lee JS, Visser M, et al,. Weight change and the conservation of lean mass in old age: The Health, Aging and Body Composition Study. Am J Clin Nutr 2005; 82: 872-878; quiz 915-876. (Pubitemid 43779703)
16. Arnold AM, Newman AB, Cushman M, et al,. Body weight dynamics and their association with physical function and mortality in older adults: The Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci 2010; 65A: 63-70.
17. Visser M, Pahor M, Taaffe DR, et al,. Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: The Health ABC Study. J Gerontol A Biol Sci Med Sci 2002; 57A: M326-M332. (Pubitemid 34464974)
18. Alley DE, Crimmins E, Bandeen-Roche K, et al,. Three-year change in inflammatory markers in elderly people and mortality: The Invecchiare in Chianti study. J Am Geriatr Soc 2007; 55: 1801-1807. (Pubitemid 350043765)
19. Kaptoge S, Di Angelantonio E, Lowe G, et al,. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: An individual participant meta-analysis. Lancet 2010; 375: 132-140.
20. Janssen I, Fortier A, Hudson R, et al,. Effects of an energy-restrictive diet with or without exercise on abdominal fat, intermuscular fat, and metabolic risk factors in obese women. Diabetes Care 2002; 25: 431-438. (Pubitemid 41103332)
21. Pou KM, Massaro JM, Hoffmann U, et al,. Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: The Framingham Heart Study. Circulation 2007; 116: 1234-1241. (Pubitemid 47517534)
22. Wannamethee SG, Shaper AG, Lennon L., Reasons for intentional weight loss, unintentional weight loss, and mortality in older men. Arch Intern Med 2005; 165: 1035-1040. (Pubitemid 40638125)
23. Gregg EW, Gerzoff RB, Thompson TJ, et al,. Intentional weight loss and death in overweight and obese U.S. adults 35 years of age and older. Ann Intern Med 2003; 138: 383-389. (Pubitemid 36262648)
24. Orwoll E, Blank JB, Barrett-Connor E, et al,. Design and baseline characteristics of the osteoporotic fractures in men (MrOS) studya-a large observational study of the determinants of fracture in older men. Contemp Clin Trials 2005; 26: 569-585. (Pubitemid 41242402)
25. Blank JB, Cawthon PM, Carrion-Petersen ML, et al,. Overview of recruitment for the Osteoporotic Fractures in Men Study (MrOS). Contemp Clin Trials 2005; 26: 557-568. (Pubitemid 41242401)
26. Washburn RA, Smith KW, Jette AM, et al,. The Physical Activity Scale for the Elderly (PASE): Development and evaluation. J Clin Epidemiol 1993; 46: 153-162. (Pubitemid 23092124)
27. Kalmijn S, Curb JD, Rodriguez BL, et al,. The association of body weight and anthropometry with mortality in elderly men: The Honolulu Heart Program. Int J Obes Relat Metab Disord 1999; 23: 395-402. (Pubitemid 29182399)
28. Janssen I, Katzmarzyk PT, Ross R., Body mass index is inversely related to mortality in older people after adjustment for waist circumference. J Am Geriatr Soc 2005; 53: 2112-2118. (Pubitemid 43001191)
29. Price GM, Uauy R, Breeze E, et al,. Weight, shape, and mortality risk in older persons: Elevated waist-hip ratio, not high body mass index, is associated with a greater risk of death. Am J Clin Nutr 2006; 84: 449-460. (Pubitemid 44699159)
30. Wedick NM, Barrett-Connor E, Knoke JD, et al,. The relationship between weight loss and all-cause mortality in older men and women with and without diabetes mellitus: The Rancho Bernardo study. J Am Geriatr Soc 2002; 50: 1810-1815. (Pubitemid 35291724)
31. Oppert JM, Charles MA, Thibult N, et al,. Anthropometric estimates of muscle and fat mass in relation to cardiac and cancer mortality in men: The Paris Prospective Study. Am J Clin Nutr 2002; 75: 1107-1113. (Pubitemid 34547542)
32. Heitmann BL, Erikson H, Ellsinger BM, et al,. Mortality associated with body fat, fat-free mass and body mass index among 60-year-old swedish men-a 22-year follow-up. The study of men born in 1913. Int J Obes Relat Metab Disord 2000; 24: 33-37. (Pubitemid 30098876)
33. Reis JP, Araneta MR, Wingard DL, et al,. Overall obesity and abdominal adiposity as predictors of mortality in U.S. White and black adults. Ann Epidemiol 2009; 19: 134-142.
34. Solomon TP, Haus JM, Kelly KR, et al,. Randomized trial on the effects of a 7-d low-glycemic diet and exercise intervention on insulin resistance in older obese humans. Am J Clin Nutr 2009; 90: 1222-1229.
35. Allison DB, Zannolli R, Faith MS, et al,. Weight loss increases and fat loss decreases all-cause mortality rate: Results from two independent cohort studies. Int J Obes Relat Metab Disord 1999; 23: 603-611. (Pubitemid 29276809)
36. Hughes VA, Frontera WR, Roubenoff R, et al,. Longitudinal changes in body composition in older men and women: Role of body weight change and physical activity. Am J Clin Nutr 2002; 76: 473-481. (Pubitemid 34804075)
37. Visser M, Goodpaster BH, Kritchevsky SB, et al,. Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons. J Gerontol A Biol Sci Med Sci 2005; 60A: 324-333. (Pubitemid 40628797)
38. Katzel LI, Bleecker ER, Colman EG, et al,. Effects of weight loss vs aerobic exercise training on risk factors for coronary disease in healthy, obese, middle-aged and older men. A randomized controlled trial. JAMA 1995; 274: 1915-1921. (Pubitemid 26003060)
39. Meckling KA, Gauthier M, Grubb R, et al,. Effects of a hypocaloric, low-carbohydrate diet on weight loss, blood lipids, blood pressure, glucose tolerance, and body composition in free-living overweight women. Can J Physiol Pharmacol 2002; 80: 1095-1105. (Pubitemid 36002667)
40. Schaap LA, Pluijm SM, Deeg DJ, et al,. Higher inflammatory marker levels in older persons: Associations with 5-year change in muscle mass and muscle strength. J Gerontol A Biol Sci Med Sci 2009; 64A: 1183-1189.
41. Morley JE, Thomas DR, Wilson MM., Cachexia: Pathophysiology and clinical relevance. Am J Clin Nutr 2006; 83: 735-743. (Pubitemid 44713134)
42. Feldman HA, Longcope C, Derby CA, et al,. Age trends in the level of serum testosterone and other hormones in middle-aged men: Longitudinal results from the Massachusetts male aging study. J Clin Endocrinol Metab 2002; 87: 589-598. (Pubitemid 34158223)
43. Luhrmann PM, Bender R, Edelmann-Schafer B, et al,. Longitudinal changes in energy expenditure in an elderly German population: A 12-year follow-up. Eur J Clin Nutr 2009; 63: 986-992.
44. Berentzen T, Sorensen TI., Effects of intended weight loss on morbidity and mortality: Possible explanations of controversial results. Nutr Rev 2006; 64: 502-507. (Pubitemid 44808266)
45. Shea MK, Houston DK, Nicklas BJ, et al,. The effect of randomization to weight loss on total mortality in older overweight and obese adults: The ADAPT Study. J Gerontol A Biol Sci Med Sci 2010; 65A: 519-525.
46. Snijder MB, Visser M, Dekker JM, et al,. The prediction of visceral fat by dual-energy X-ray absorptiometry in the elderly: A comparison with computed tomography and anthropometry. Int J Obes Relat Metab Disord 2002; 26: 984-993. (Pubitemid 34756183)
47. Visser M, Fuerst T, Lang T, et al,. Validity of fan-beam dual-energy X-ray absorptiometry for measuring fat-free mass and leg muscle mass. Health, aging, and body composition study-dual-energy X-ray absorptiometry and body composition working group. J Appl Physiol 1999; 87: 1513-1520.
48. Salamone LM, Fuerst T, Visser M, et al,. Measurement of fat mass using DEXA: A validation study in elderly adults. J Appl Physiol 2000; 89: 345-352. (Pubitemid 30482598)