Insulin suppresses transactivation by CAAT/Enhancer-binding proteins β (C/EBPβ). Signaling to p300/CREB-binding protein by protein kinase B disrupts interaction with the major activation domain of C/EBPβ

Journal of Biological Chemistry

Volumn 276, Issue 11, 2001, Pages 8516-8523

  Guo, Shaodong ^a,d   Cichy, Stephen B ^a   He, Xiaowei ^a   Yang, Qunying ^b   Ragland, Maria ^b   Ghosh, Asish K ^a,e   Johnson, Peter F ^c   Unterman, Terry G ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b Research Genetics   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d LEXICON PHARMACEUTICALS INC   (United States)

^e UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHEMICAL BONDS; GENES; INSULIN; PROTEINS; TISSUE;

TRANSACTIVATION;

BIOCHEMISTRY;

2 MORPHOLINO 8 PHENYLCHROMONE; CCAAT ENHANCER BINDING PROTEIN BETA; HYBRID PROTEIN; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; RAPAMYCIN; S6 KINASE; SOMATOMEDIN BINDING PROTEIN 1; CCAAT ENHANCER BINDING PROTEIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; LEUCINE ZIPPER PROTEIN; NUCLEAR PROTEIN; ONCOPROTEIN; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PROTEIN SERINE THREONINE KINASE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; BINDING SITE; CELL STRAIN HEPG2; CONSENSUS SEQUENCE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; INSULIN RESPONSE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; REPORTER GENE; SITE DIRECTED MUTAGENESIS; TRANSACTIVATION; AMINO ACID SEQUENCE; DRUG EFFECT; GENETICS; MOLECULAR GENETICS; PHYSIOLOGY; STRUCTURE ACTIVITY RELATION;

MAMMALIA;

AMINO ACID SEQUENCE; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CCAAT-ENHANCER-BINDING PROTEINS; INSULIN; LEUCINE ZIPPERS; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; STRUCTURE-ACTIVITY RELATIONSHIP; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS;

EID: 0035896580     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008542200     Document Type: Article

References (65)

1. Mandrup, S., and Lane, M. D. (1997) J. Biol. Chem. 272, 5367-5370
2. Darlington, G. J., Wang, N., and Hanson, R. W. (1995) Curr. Opin. Genet. Dev. 5, 565-570
3. Lee, Y.-H., Sauer, B., Johnson, P. F., and Gonzalez, F. J. (1997) Mol. Cell. Biol. 17, 6014-6022
4. Liu, S., Croniger, C., Arizmendi, C., Harada-Shiba, M., Ren, J., Poli, V., Hanson, R. W., and Friedman, J. E. (1999) J. Clin. Invest. 103, 207-213
5. Croniger, C., Trus, M., Lysek-Stupp, K., Cohen, H., Liu, Y., Darlington, G. J., Poli, V., Hanson, R. W., and Reshef, L. (1997) J. Biol. Chem. 272, 26306-26312
6. Roesler, W. J., Crosson, S. M., Vinson, C., and McFie, P. J. (1996) J. Biol. Chem. 271, 8060-8074
7. Park, E. A., Roesler, W. J., Liu, J., Klemm, D. J., Gurney, A. L., Thatcher, J. D., Shuman, J., Friedman, A., and Hanson, R. (1990) Mol. Cell. Biol. 10, 6264-6272
8. Yamada, K., Duong, D. T., Scott, D. K., Wang, J. C., and Granner, D. K. (1999) J. Biol. Chem. 274, 5880-5887
9. Yeagley, D., Moll, J., Vinson, C. A., and Quinn, P. G. (2000) J. Biol. Chem. 275, 17814-17820
10. Park, E. A., Song, S., Vinson, C., and Roesler, W. J. (1999) J. Biol. Chem. 274, 211-217
11. Ghosh, A. K., Lacson, R., Liu, P., Cichy, S. B., Danilkovich, A., Guo, S., and Unterman, T. G. (2000) J. Biol. Chem. 276, 8507-8515
12. Cichy, S. B., Uddin, S., Danilkovich, A., Guo, S., Klippel, A., and Unterman, T. G. (1998) J. Biol. Chem. 273, 6482-6487
13. Andjelkovie, M., Alessi, D. R., Meier, R., Fernandez, A., Lamb, N. J. C., Frech, M., Cron, P., Cohen, P., Lucocq, J. M., and Hemmings, B. A. (1997) J. Biol. Chem. 272, 31515-31524
14. Guo, S., Rena, G., Cichy, S., He, X., Cohen, P., and Unterman, T. (1999) J. Biol. Chem. 274, 17184-17192
15. Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., Anderson, M. J., Arden, K. C., Blenis, J., and Greenberg, M. E. (1999) Cell 96, 857-868
16. Kops, G. J., de Ruiter, N. D., Vries-Smits, A. M., Powell, D. R., Bos, J. L., and Burgering, B. M. (1999) Nature 398, 630-634
17. Mink, S., Haenig, B., and Klempnauer, K.-H. (1997) Mol. Cell. Biol. 17, 6609-6617
18. Arany, Z., Newsome, D., Oldread, E., Livingston, D. M., and Eckner, R. (1995) Nature 374, 81-84
19. Korzus, E., Torchia, J., Rose, D. W., Xu, L., Kurokawa, R., McInerney, E. M., Mullen, T. M., Glass, C. K., and Rosenfeld, M. G. (1998) Science 279, 703-707
20. Yang, X.-J., Ogryzko, V. V., Nishikawa, J., Howard, B. H., and Nakatani, Y. (1996) Nature 382, 319-324
21. Chrivia, J. C., Kwok, R. P. S., Lamb, N., Hagiwara, M., Montminy, M. R., and Goodman, R. H. (1993) Nature 365, 855-859
22. Felzien, L. K., Farrell, S., Betts, J. C., Mosavin, R., and Nabel, G. J. (1999) Mol. Cell. Biol. 19, 4241-4246
23. Nakajima, T., Fukamizu, A., Takahashi, J., Gage, F. H., Fisher, T., Blenis, J., and Montminy, M. R. (1996) Cell 86, 465-474
24. Eckner, R., Ludlow, J. W., Lill, N. L., Oldread, E., Arany, Z., Modjtahedi, N., DeCaprio, J. A., Livingston, D. M., and Morgan, J. A. (1996) Mol. Cell. Biol. 16, 3454-3464
25. Lee, J., See, R. H., Deng, T., and Shi, Y. (1996) Mol. Cell. Biol. 16, 4312-4326
26. Bannister, A. J., and Kouzarides, T. (1995) EMBO J. 14, 4758-4762
27. Sartorelli, V., Huang, J., Hamamori, Y., and Kedes, L. (1997) Mol. Cell. Biol. 17, 1010-1026
28. Lee, J., See, R. H., Galvin, K. M., Wang, J., and Shi, Y. (1995) Nucleic Acids Res. 23, 925-931
29. Yang, C., Shapiro, L. H., Rivera, M., Kumar, A., and Brindle, P. K. (1998) Mol. Cell. Biol. 18, 2218-2229
30. Sheppard, K. A., Phelps, K. M., Williams, A. J., Thanos, D., Glass, C. K., Rosenfeld, M. G., Gerritsen, M. E., and Collins, T. (1998) J. Biol. Chem. 273, 29291-29294
31. Nasrin, N., Ogg, S., Cahill, C. M., Biggs, W., Nui, S., Dore, J., Calvo, D., Shi, Y., Ruvkun, G., and Alexander-Bridges, M. C. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 10412-10417
32. Williams, S. C., Baer, M., Dillner, A. J., and Johnson, P. F. (1995) EMBO J. 14, 3170-3183
33. Raychaudhuri, P., Bagchi, S., Devoto, S. H., Kraus, V. B., Moran, E., and Nevins, J. R. (1991) Genes Dev. 5, 1200-1211
34. Hara, K., Yonezawa, K., Sakaue, H., Ando, A., Kotani, K., Kitamura, T., Kitamura, Y., Ueda, H., Stephens, L., Jackson, T. R., Hawkins, P. T., Dhand, R., Clark, A. E., Holman, G. D., Waterfield, M. D., and Kasuga, M. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 7415-7419
35. Dudek, H., Datta, S. R., Franke, T. F., Birnbaum, M. J., Yao, R. Cooper, G. M., Segal, R. A., Kaplan, D. R., and Greenberg, M. E. (1997) Science 275, 661-665
36. Ron, D., and Habener, J. F. (1992) Genes Dev. 6, 439-453
37. Eckner, R., Ewen, M. E., Newsome, D., Gerdes, M., DeCaprio, J. A., Lawrence, J. B., and Livingston, D. M. (1994) Genes Dev. 869-884
38. Dyson, N., and Harlow, E. (1992) Cancer Surv. 12, 161-195
39. Pouponnot, C., Jayaraman, L., and Massague, J. (1998) J. Biol. Chem. 273, 22865-22868
40. Alessi, D. R., Caudwell, F. B., Andjelkovie, M., Hemmings, B. A., and Cohen, P. (1996) FEBS Lett. 399, 333-338
41. Johnson, P. F., and Williams, S. C. (1994) in Liver Gene Expression (Tronche, F., and Yaniv, M., eds) pp. 232-257, R. G. Landes Co., Austin, TX
42. Cao, Z., Umek, R. M., and McKnight, S. L. (1991) Genes Dev. 5, 1538-1552
43. Screpanti, I., Romani, L., Musiani, P., Modesti, A., Fattori, E., Lazzaro, D., Sellitto, C., Scarpa, S., Bellavia, D., Lattanzio, G., Bistoni, F., Frati, L., Cortese, R., Gulino, A., Ciliberto, G., Costantini, F., and Poli, V. (1995) EMBO J. 14, 1932-1941
44. Robinson, G. W., Johnson, P. F., Hennighausen, L., and Sterneck, E. (1998) Genes Dev. 12, 1907-1916
45. Sterneck, E., Tessarollo, L., and Johnson, P. F. (1997) Genes Dev. 11, 2153-2162
46. Sutherland, C., O'Brien, R. M., and Granner, D. K. (1995) J. Biol. Chem. 270, 15501-15506
47. Dickens, M., Svitek, C. A., Culbert, A. A., O'Brien, R. M., and Tavare, J. M. (1998) J. Biol. Chem. 273, 20144-20149
48. Schmoll, D., Walker, K. S., Alessi, D. R., Grempler, R., Burchell, A., Guo, S., Walther, R., and Unterman, T. G. (2000) J. Biol. Chem. 275, 36324-36333
49. Biggs, W. H., III, Meisenhelder, J., Hunter, T., Cavenee, W. K., and Arden, K. C. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 7421-7426
50. McKnight, S. L. (1992) in Transcriptional Regulation, (McKnight, S. L., and Yamamoto, K. R., eds) pp. 771-795, Cold Spring Harbor Press, Cold Spring Harbor, NY
51. Lee, Y.-H., Williams, S. C., Baer, M., Sterneck, E., Gonzalwz, F. J., and Johnson, P. F. (1997) Mol. Cell. Biol. 17, 2038-2047
52. Wegner, M., Cao, Z., and Rosenfeld, M. G. (1992) Science 256, 370-373
53. Nakajima, T., Kinoshita, S., Sasagawa, T., Sasaka, K., Naruto, M., Kishimoto, T., and Akira, S. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 2207-2211
54. Trautwein, C., van der, G. P., Karin, M., Hunter, T., and Chojkier, M. (1994) J. Clin. Invest. 93, 2554-2561
55. Buck, M., Poli, V., van der Geer, P. T., Chojkier, M., and Hunter, T. (1999) Mol. Cell. 4, 1087-1092
56. Vanhaesebroeck, B., and Alessi, D. R. (2000) Biochem. J. 346, 561-76
57. Belham, C., Wu, S., and Avruch, J. (1999) Curr. Biol. 9, 93-96
58. Kandel, E. S., and Hay, N. (1999) Exp. Cell. Res. 253, 210-29
59. Gonzalez, G. A., and Montminy, M. R. (1989) Cell 59, 675-80
60. Goldman, P. S., Tran, V. K., and Goodman, R. H. (1997) Res. Prog. Horm. Res. 52, 103-120
61. Kamei, Y., Lan, X., Heinzel, T., Torchia, J., Kurokawa, R., Gloss, B., Lin, S.-C., Heyman, R. A., Rose, D. W., Glass, C. K., and Rosenfeld, M. G. (1996) Cell 85, 403-414
62. Unterman, T. G., Fareeduddin, A., Harris, M. A., Goswami, R. G., Porcella, A., Costa, R. H., and Lacson, R. G. (1994) Biochem. Biophys. Res. Commun. 203, 1835-4194
63. Imai, E., Stromstedt, P. E., Quinn, P. G., Carlstedt-Duke, J., Gustafsson, J. A., and Granner, D. K. (1990) Mol. Cell Biol. 10, 4712-4719
64. Tomizawa, M., Kumar, A., Perrot, V., Nakae, J., Accili, D., Kumaro, A., and Rechler, M. (2000) J. Biol. Chem. 275, 7289-7295
65. Giordano, A., and Avantaggiati, M. L. (1999) Cell. Physiol. 181, 218-230