Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory β-cell hyperplasia

Diabetes

Volumn 49, Issue 11, 2000, Pages 1880-1889

  Kubota, Naoto ^a   Tobe, Kazuyuki ^a   Terauchi, Yasuo ^a   Eto, Kazuhiro ^a   Yamauchi, Toshimasa ^a   Suzuki, Ryo ^a   Tsubamoto, Yoshiharu ^a   Komeda, Kajuro ^b   Nakano, Ryosuke ^a   Miki, Hiroshi ^a   Satoh, Shinobu ^c   Sekihara, Hisahiko ^c   Sciacchitano, Salvatore ^f   Lesniak, Maxine ^f   Aizawa, Shinichi ^e   Nagai, Ryozo ^a   Kimura, Satoshi ^a   Akanuma, Yasuo ^d   Taylor, Simeon I ^f   Kadowaki, Takashi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOKYO MEDICAL UNIVERSITY   (Japan)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

^d INSTITUTE FOR ADULT DISEASES   (Japan)

^e KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^f NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE 2;

ANIMAL CELL; ARTICLE; CELL HYPERPLASIA; CONTROLLED STUDY; GENE DISRUPTION; INSULIN RELEASE; INSULIN RESISTANCE; KNOCKOUT MOUSE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0033755408     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.49.11.1880     Document Type: Article

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