The improvement of hypertension by probiotics: Effects on cholesterol, diabetes, renin, and phytoestrogens

International Journal of Molecular Sciences

Volumn 10, Issue 9, 2009, Pages 3755-3775

  Lye, Huey Shi ^a   Kuan, Chiu Yin ^a   Ewe, Joo Ann ^a   Fung, Wai Yee ^a   Liong, Min Tze ^a  

^a Universiti Sains Malaysia   (Malaysia)

Author keywords

Antihypertension; Cholesterol; Diabetes; Phytoestrogen; Probiotic; Renin

Indexed keywords

17ALPHA ESTRADIOL; AGLYCONE; ANTIHYPERTENSIVE AGENT; BILE ACID; DAIDZEIN; DAIDZIN; ESTRADIOL; ESTROGEN; ESTRONE; GENISTEIN; GENISTIN; GLICLAZIDE; GLUCOSIDE; GLYCITEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; ISOFLAVONE; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; ORAL ANTIDIABETIC AGENT; PHYTOESTROGEN; PROBIOTIC AGENT; PROGESTERONE; RENIN; SEX HORMONE; SULFONYLUREA DERIVATIVE; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL; YOGHURT;

BIFIDOBACTERIUM; BILE ACID SYNTHESIS; BLOOD PRESSURE; BREAST CANCER; CANCER RISK; CHEESE; CHEMICAL STRUCTURE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL METABOLISM; COLONY FORMING UNIT; DAIRY PRODUCT; DIABETES MELLITUS; DIET SUPPLEMENTATION; DRUG POTENTIATION; ESSENTIAL HYPERTENSION; ESTROGEN METABOLISM; FERMENTED PRODUCT; GLUCOSE BLOOD LEVEL; HORMONAL REGULATION; HORMONE SUBSTITUTION; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; HYPOCHOLESTEROLEMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; LACTOBACILLUS; LIPID BLOOD LEVEL; MILK; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; POSTMENOPAUSE; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVIEW; STREPTOCOCCUS THERMOPHILUS; STREPTOZOCIN DIABETES; TREATMENT OUTCOME;

ANTIHYPERTENSION; CHOLESTEROL; DIABETES; PHYTOESTROGEN; PROBIOTIC; RENIN;

ANIMALS; CHOLESTEROL; DIABETES MELLITUS, TYPE 2; HUMANS; HYPERTENSION; PHYTOESTROGENS; PROBIOTICS; RENIN;

EID: 70350043072     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms10093755     Document Type: Review

References (77)

1. FitzGerald, R.J.; Murray, B.A.; Walsh, D.J. Hypotensive peptides from milk proteins. J. Nutr. 2004, 134, 980S-988S.
2. Rahmouni, K.; Correia, M.L.G.; Haynes, W.G.; Mark, A.L. Obesity-associated hypertension. Hypertension 2005, 45, 9-14.
3. Saad, M.F.; Rewers, M.; Selby, J.; Howard, G.; Jinagouda, S.; Fahmi, S.; Zaccaro, D.; Bergman, R.N.; Savage, P.J.; Haffner, S.M. Insulin resistance and hypertension: The insulin resistance artherosclerosis study. Hypertension 2004, 43, 1324-1331. (Pubitemid 38691757)
4. Natali, A.; Ferrannini, E. Hypertension, insulin resistance and the metabolic syndrome. Endocrinol. Metab. Clin. North. Am. 2004, 33, 417-429.
5. Inagami, T. The renin-angiotensin system. Essays Biochem. 1992, 28, 147-164.
6. Yekeen, L.A.; Sanusi, R.A.; Ketiku, A.O. Prevalence of obesity and high level of cholesterol in hypertension: Analysis of data from the university college hospital, Ibadan. Afr. J. Biomed. Res. 2003, 6, 129-132.
7. Mann, G.V.; Spoerry, A. Studies of a surfactant and cholesteremia in the Maasai. Am. J. Clin. Nutr. 1974, 27, 464-469.
8. Goel, A.K.; Dilbaghi, N.; Kamboj, D.V.; Singh, L. Probiotics: Microbial therapy for health modulation. Defence. Sci. J. 2006, 56, 513-529.
9. Kieling, G.; Schneider, J.; Jahreis, G. Long-term consumption of fermented dairy products over 6 months increases HDL cholesterol. Eur. J. Clin. Nutr. 2002, 56, 843-849.
10. Sindhu, S.C.; Khetarpaul, N. Effect of feeding probiotic fermented indigenous food mixture on serum cholesterol levels in mice. Nutr. Res. 2003, 23, 1071-1080. (Pubitemid 36936214)
11. de Rodas, B.Z.; Gilliland, S.E.; Maxwell, C.V. Hypocholesterolemic action of Lactobacillus acidophilus ATCC and calcium in swine with hypercholesterolemia induced by diet. J. Dairy Sci. 1996, 79, 2121-2128.
12. Park, Y.H.; Kim, J.G.; Shin, Y.W.; Kim, S.H.; Whang, K.Y. Effect of dietary inclusion of Lactobacillus acidophilus ATCC 43121 on cholesterol metabolism in rats. J. Microbiol. Biotechnol. 2007, 17, 655-662.
13. Pigeon, R.M.; Cuesta, E.P.; Gilliland, S.E. Binding of free bile acids by cells of yogurt starter culture bacteria. J. Dairy Sci. 2002, 85, 2705-2710.
14. Liong, M.T.; Shah, N.P. Acid and bile tolerance and the cholesterol removal ability of bifidobacteria strains. Biosci. Micro. 2005a, 24, 1-10.
15. Tahri, K.; Crociani, J.; Ballongue, J.; Schneider, F. Effects of three strains of bifidobacteria on cholesterol. Lett. Appl. Microbiol. 1995, 21, 149-151.
16. Aloglu, H.; Oner, Z. Assimilation of cholesterol in broth, cream, and butter by probiotic bacteria. Eur. J. Lipid Sci. Technol. 2006, 108, 709-713. (Pubitemid 44475604)
17. Kimoto-Nira, H.; Mizumachi, K.; Nomura, M.; Kobayashi, M.; Fujita, Y.; Okamoto, T.; Suzuki, I.; Tsuji, N.M.; Kurisaki, J.-I.; Ohmomo, S. Lactococcus sp. as potential probiotic lactic acid bacteria. Japan Agr. Res. Quart. 2007, 41, 181-189. (Pubitemid 350206964)
18. Razin, S. Cholesterol incorporation into bacterial membranes. J. Bacteriol. 1975, 124, 570-572.
19. Tani, H.; Sato, M.; Tsuchiya, H.; Namikawa, I. Cholesterol incorporation into bacillus megaterium without compositional modification of membrane lipids in response to changes of the membrane functions. Curr. Microbiol. 1993, 26, 253-256. (Pubitemid 23110447)
20. Noh, D.O.; Kim, S.H.; Gilliland, S.E. Incorporation of cholesterol into the cellular membrane of Lactobacillus acidophilus ATCC 43121. J. Dairy Sci. 1997, 80, 3107-3113.
21. Kiatpapan, P.; Kobayashi, H.; Sakaguchi, M.; Ono, H.; Yamashita, M.; Kaneko, Y.; Murooka, Y. Molecular characterization of Lactobacillus plantarum genes for β-ketoacyl-acyl carrier protein synthase III (fabH) and acetyl coenzyme A carboxylase (accBCDA), which are essential for fatty acid biosynthesis. Appl. Environ. Microbiol. 2001, 67, 426-433. (Pubitemid 32044446)
22. Liong, M.T.; Shah, N.P. Roles of probiotics and prebiotics on cholesterol: The hypothesized mechanisms. Nutrafoods 2005b, 4, 45-57.
23. Tanaka, H.; Hashiba, H.; Kok, J.; Mierau, I. Bile salt hydrolase of Bifidobacterium longumbiochemical and genetic characterization. Appl. Environ. Microbiol. 2000, 66, 2502-2512. (Pubitemid 30353957)
24. Taranto, M.P.; Sesma, F.; Valdez, G.F. Localization and primary characterization of bile salt hydrolase from Lactobacillus reuteri. Biotechnol. Lett. 1999, 21, 935-938. (Pubitemid 30040988)
25. Gress, T.W.; Ress, T.W.; Nieto, F.J.; Shahar, E.; Wofford, M.R.; Bramcati, F.L. The atherosclerosis risk in communities s. hypertension and antihypertensive therapy as risk factors for type 2 diabetes mellitus. N. Engl. J. Med. 2000, 342, 905-912.
26. Sowers, J.; Epstein, M.; Frohlich, E.D. Diabetes, hypertension, and cardiovascular disease: An update. Hypertension 2001, 37, 1053-1059.
27. Nishimura, R.; LaPorte, R.E.; Dorman, J.S.; Tajima, N.; Becker, D.; Orchard, T.J. Mortality trends in type 1 diabetes: The allegheny county (pennsylvania) registry 1965-1999. Diabetes Care 2001, 24, 823-827.
28. Yadav, H.; Jain, S.; Sinha, P.R. Antidiabetic effect of probiotic dahi containing Lactobacillus acidophilus and Lactobacillus casei in high fructose fed rats. Nutr. 2006, 23, 62-68.
29. Klabunde, R. Cardiovascular Physiology Concepts; Lippincott Williams & Wilkins: Philadelphia, PA, USA, 2005.
30. Lind, L.; Bente, C.; Lithell, H. Prevalence of insulin resistance in essential hypertension. Hypertension 1995, 13, 1457-1462. (Pubitemid 26015762)
31. UK Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. Bri. Med. J. 1998, 317, 703-713.
32. Serino, M.; Luche, E.; Chabo, C.; Amar, J.; Burcelin, R. Intestinal microflora and metabolic diseases. Diabetes Metab. 2009, in press.
33. Cani, P.; Neyrinck, A.M.; Fava, F.; Knauf, K.; Burcelin, R.G.; Tuohy, K.M. Selective increases of bifidobacteria in gut microflora improves high-fat diet-induced diabetes in mice through a mechanism associated with endotoxemia. Diabetol. 2007, 50, 2374-2383.
34. Cani, P.; Delzenne, N.M.; Amar, J.; Burcelin, R. Role of gut microflora in the development of obesity and insulin resistance following high-fat diet feeding. Pathol. Biol. 2008, 56, 305-309.
35. Arunachalam, K.; Gill, H.S.; Chandra, R.K. Enhancement of natural immune function by dietary consumption of bifidobacterium lactis (HN019). Eur. J. Clin. Nutr. 2000, 54, 263-267.
36. Matsuzaki, T.; Yamazaki, R.; Hashimoto, S.; Yokokura, T. Antidiabetic effect of an oral administration of lactobacillus casei in a non-insulin dependent diabetes mellitus (NIDDM) model using KK-Ay mice. Endocrin. J. 1997a, 44, 357-365. (Pubitemid 27310421)
37. Tuohy, K.; Probert, H.M.; Smejkal, C.W.; Gibson, G.R. Using probiotics and prebiotics to improve gut health. Therapeutic Focus 2003, 8, 692-700. (Pubitemid 36970000)
38. Al-Salami, H.; Butt, G.; Fawcett, J.P.; Tucker, I.G.; Golocorbin-Kon, S.; Mikov, M. Probiotic treatment reduces blood glucose levels and increases systemic absorption of gliclazide in diabetic rats. Eur. J. Drug Metab. Pharmacokin. 2008, 33, 101-106.
39. Basciano, H.; Federico, L.; Adeli, K. Fructose, insulin resistance and metabolic dyslipidemia. Nutr. Metab. 2005, 2, 1-14.
40. Boden, G.; Shulman, G.I. Free fatty acids in obesity and type 2 diabetes: Defining their role in the development of insulin resistance and β-cell dysfunction. Eur. J. Clin. Invest 2002, 32, 14S-23S.
41. Matsuzaki, T.; Nagata, Y.; Kado, S.; Uchida, K.; Hashimoto, S.; Yokokura, T. Effect of oral administration of Lactobacillus casei on alloxan-induced diabetes in mice. Acta. Pathol. Microbiol. Immunol. Scand 1997b, 105, 637-642. (Pubitemid 27380827)
42. Matsuzaki, T.; Nagata, Y.; Kado, S.; Uchida, K.; Kato, I.; Hashimoto, S.; Yokokura, T. Prevention of onset in an insulin-dependent diabetes mellitus model, NOD mice, by oral feeding of Lactobacillus casei. Acta. Pathol. Microbiol. Immunol. Scand. 1997c, 105, 643-649.
43. Tabuchi, M.; Ozaki, M.; Tamura, A.; Yamada, N.; Ishida, T.; Hosoda, M.; Hosono, A. Antidiabetic effect of Lactobacillus GG in streptozotocin-induced diabetic rats. Biosci. Biotechnol. Biochem. 2003, 67, 1421-1424. (Pubitemid 39251845)
44. Li, Z.; Yang, S.; Lin, H.; Huang, J.; Watkins, P.A.; Moser, A.B. Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease. Hepatology 2003, 37, 343-350.
45. Saito, T. Advances in Experimental Medicine and Biology: Bioactive Components of Milk; Bösze, Z., Ed.; Springer: New York, NY, USA, 2008.
46. Korhonen, H. Milk-derived bioactive peptides: From science to applications. J. Func. Foods 2009, 1, 177-187.
47. FitzGerald, R.J.; Murray, B.A. Bioactive peptides and lactic fermentations. Int. J. Dairy Technol. 2006, 59, 118-125.
48. Yamamoto, N.; Takano, T. Antihypertensive peptides derived from milk proteins. Nahrung 1999, 43, 159-164. (Pubitemid 129570442)
49. Donkor, O.N.; Henriksson, A.; Vasiljevic, T.; Shah, N.P. α-Galactosidase and proteolytic activities of selected probiotic and dairy cultures in fermented soymilk. Food Chem. 2007, 104, 10-20.
50. Ong, L.; Shah, N.P. Release and identification of angiotensin-converting enzyme-inhibitory peptides as influenced by ripening temperaturws and probiotic adjuncts in Cheddar cheeses. LWTFood Sci. Technol. 2008, 41, 1555-1566.
51. Rhyänen, E.L.; Pihlanto-Leppälä, A.; Pahkala, E. A new type of ripened: Low-fat cheese with bioactive properties. Int. Diary J. 2001, 11, 441-447. (Pubitemid 32752183)
52. Ng, K.H.; Lye, H.S.; Easa, A.M.; Liong, M.T. Growth characteristics and bioactivity of probiotics in tofu-based medium during storage. Ann. Microbiol. 2008, 58, 477-487.
53. Fung, W.Y.; Woo, Y.P.; Liong, M.T. Optimization of growth of Lactobacillus acidophilus FTCC 0291 and evaluation of growth characteristics in soy whey medium: A response surface methodology approach. J. Agr. Food Chem. 2008, 56, 7910-7918.
54. Sipola, M.; Finckenberg, P.; Santisteban, J.; Korpela, R.; Vapaatalo, H.; Nurminen, M.L. Long-term intake of milk peptides attenuates development of hypertension in spontaneously hypertensive rats. J. Physiol. Pharmacol. 2001, 52, 745-754.
55. Hata, Y.; Yamamoto, M.; Ohni, M.; Nakajima, K.; Nakamura, Y.; Takano, T. A placebocontrolled study of the effect of sour milk on blood pressure in hypertensive subjects. Am. J. Clin. Nutr. 1996, 64, 767-771. (Pubitemid 26398281)
56. Jauhiainen, T.; Collin, M.; Narva, M.; Poussa, T.; Korpela, R. Effect of long-term intake of milk peptides and minerals on blood pressure and arterial function in spontaneously hypertensive rats. Milchwissenschaft 2005, 60, 358-362. (Pubitemid 41360660)
57. Seppo, L.; Jauhiainen, T.; Poussa, T.; Korpela, R. A fermented milk high in bioactive peptides has a blood pressure-lowering effect in hypertensive subjects. Am. J. Clin. Nutr. 2003, 77, 326-330. (Pubitemid 36133373)
58. Algerholm-Larsen, L.; Raben, A.; Haulrik, N.; Hansen, A.S.; Manders, M.; Astrup, A. Effect of 8 week intake of probiotic milk products on risk factors for cardiovascular diseases. Eur. J. Clin. Nutr. 2000, 54, 288-297. (Pubitemid 30201447)
59. Aihara, K.; Kajimoto, O.; Hirata, H.; Takahashi, R.; Nakamura, Y. Effect of powdered fermented milk with Lactobacillus helveticus on subjects with high-normal blood pressure or milk hypertension. J. Am. Col. Nutr. 2005, 4, 257-265. (Pubitemid 43121892)
60. Mizushima, S.; Ohshige, K.; Watanabe, J.; Kimura, M.; Kadowaki, T.; Nakamura, Y.; Tochikubo, O.; Ueshima, H. Randomized controlled trial of sour milk on blood pressure in borderline hypertensive men. Am. J. Hypertens. 2004, 17, 701-706. (Pubitemid 39091551)
61. Tuomilehto, J.; Lindström, J.; Hyyrynen, J.; Korpela, R.; Karhunen, M.L.; Mikkola, L.; Jauhiainen, T.; Seppo, L.; Nissinen, A. Effect of ingesting sour milk fermented by Lactobacillus helveticus bacteria on blood pressure in subjects with mild hypertension. J. Human Hyperten. 2004, 18, 795-802. (Pubitemid 39530092)
62. Dubey, R.K.; Oparil, S.; Imthurn, B.; Jackson, E.K. Sex hormones and hypertension. Cardio. Res. 2002, 53, 688-708.
63. Reckelhoff, J.F.; Fortepiani, L.A. Novel mechanisms responsible for postmenopausal hypertension. Hypertension 2004, 43, 918-923.
64. Setchell, K. Phytoestrogens: The biochemistry, physiology, and implications for human health of soy isoflavones. Am. Clin. Nutr. 1998, 68, 1333S-1346S.
65. Wood, C.E.; Register, T.C.; Cline, J.M. Soy isoflavonoid effects on endogenous estrogen metabolism in postmenopausal female monkeys. Carcinogenesis 2007, 28, 801-808.
66. Cornwell, T.; Cohick, W.; Raskin, I. Dietary phytoestrogens and health. Phytochem. 2004, 65, 995-1016.
67. Cohen, L.A.; Crespin, J.S.; Wolper, C.; Zang, E.A.; Pittman, B.; Zhao, Z.; Holt, P.R. Soy isoflavone intake and estrogen excretion patterns in young women: Effect of probiotic administration in vivo. Int. J. Exp. Clin. Pathophysiol. Drug Res. 2007, 21, 507-512.
68. Kano, M.; Takayanagi, T.; Harada, K.; Sawada, S.; Ishikawa, F. Bioavailability of isoflavones after ingestion of soy beverages in healthy adults. J. Nutr. 2006, 136, 2291-2296. (Pubitemid 44329984)
69. Steinberg, F.M.; Guthrie, N.L.; Villablanca, A.C.; Kumar, K.; Murray, M.J. Soy protein with isoflavones has favorable effects on endothelial function that are independent of lipid and antioxidant effects in healthy postmenopausal women. Am. J. Clin. Nutr. 2003, 78, 123-130.
70. Hooper, L.; Ryder, J.J.; Kurzer, M.S.; Lampe, J.W.; Messina, M.J.; Phipps, W.R.; Cassidy, A. Effects of soy protein and isoflavones on circulating hormone concentrations in pre- and postmenopausal women: A systematic review and meta-analysis. Human Reprod. 2009, http://humupd.oxfordjournals.org/cgi/ content/abstract/dmp010 (accessed June 9, 2009).
71. Adlercreutz, H.; Markkanen, H.; Watanabe, S. Plasma concentrations of phyto-oestrogens in Japanese men. Lancet 1993, 342, 1209-1210. (Pubitemid 23331713)
72. Greany, K.A.; Nettleton, J.A.; Wangen, K.E.; Thomas, W.; Kurzer, M.S. Probiotic consumption does not enhance the cholesterol-lowering effect of soy in postmenopausal women. J. Nutr. 2004, 134, 3277-3283.
73. Nettleton, J.A.; Greany, K.A.; Thomas, W.; Wangen, K.E.; Adlercreutz, H.; Kurzer, M.S. The effect of soy consumption on the urinary 2:16-hydroxyestrone ratio in postmenopausal women depends on equol production status but is not influenced by probiotic consumption. J. Nutr. 2005, 135, 603-608.
74. Tsangalis, D.; Ashton, J.F.; McGill, A.E.J.; Shah, N.P. Enzymic transformation of isoflavone phytoestrogens in soymilk by β-glucosidase- producing Bifidobacteria. J. Food Sci. 2002, 67, 3104-3113.
75. Atkinson, C.; Frankenfeld, C.L.; Lampe, J.W. Gut bacterial metabolism of the soy isoflavone daidzein: exploring the relevance to human health. Exp. Biol. Med. 2005, 230, 155-170.
76. Chien, H.L.; Huang, H.Y.; Chou, C.C. Transformation of isoflavone phytoestrogens during the fermentation of soymilk with lactic acid bacteria and bifidobacteria. Food Microbiol. 2006, 23, 772-778. (Pubitemid 44016026)
77. Pham, T.T.; Shah, N.P. Biotransformation of isoflavone glycosides by Bifidobacterium animalis in soymilk supplemented with skim milk powder. J. Food Sci. 2007, 72, M316-M324.