High selenium impairs hepatic insulin sensitivity through opposite regulation of ROS

Toxicology Letters

Volumn 224, Issue 1, 2014, Pages 16-23

  Wang, Xin ^a   Zhang, Wei ^a   Chen, Hongli ^a   Liao, Nai ^a   Wang, Zhao ^a   Zhang, Xiaodi ^a   Hai, Chunxu ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Chromium; Hepatic insulin resistance; ROS; Selenium; Selenoprotein

Indexed keywords

ACETYL COENZYME A; CHROMIUM; FATTY ACID; GLUCOSE; GLUTATHIONE PEROXIDASE; INSULIN; LIPID; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SELENIUM; SELENOPROTEIN P; SODIUM SELENITE; TRICHLOROACETIC ACID;

ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; ATTENUATION; BIOCHEMISTRY; CONTROLLED STUDY; ELECTRON; FATTY ACID OXIDATION; GLUCONEOGENESIS; GLUCOSE METABOLISM; GLUCOSE TOLERANCE TEST; IMMUNOFLUORESCENCE; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LIPID METABOLISM; LIPOLYSIS; LIVER CELL; MITOCHONDRION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AKT; AREA UNDER THE CURVE; AUC; CAMP RESPONSE ELEMENT BINDING PROTEIN; CARBONYL CYANIDE 3-CHLOROPHENYLHYDRAZONE; CARNITINE PALMITOYLTRANSFERASE 1; CCCP; CHROMIUM; CHROMIUM PICOLINATE; CPT1; CREB; CRPIC; DIPHENYLIODONIUM; DPI; ETO; ETOMOXIR; FAO; FATTY ACID OXIDATION; FFAS; FREE FATTY ACIDS; G6P; GLUCOSE-6-PHOSPHATE; GLUTATHIONE PEROXIDASES; GPX; HEPATIC INSULIN RESISTANCE; HORMONE-SENSITIVE LIPASE; HSL; INTRAPERITONEAL GLUCOSE TOLERANCE TEST; INTRAPERITONEAL INSULIN TOLERANCE TEST; IPGTT; IPITT; MERCAPTOSUCCINIC ACID; MITOCHONDRIAL OXIDATIVE PHOSPHORYLATION; MITOQ; MITOQUINONE; MSA; OLIGO; OLIGOMYCIN; OXPHOS; PEPCK; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PHOSPHOENOLPYRUVATE CARBOXYKINASE; PPARΓ; PROTEIN KINASE B; REACTIVE OXYGEN SPECIES; ROS; ROT; ROTENONE; SE; SELENIUM; SELENOPROTEIN; SELENOPROTEIN P; SEP; SODIUM SALICYLATE; SS; T2DM; TCA; TRICHLOROACETIC ACID; TYPE 2 DIABETES MELLITUS;

ANIMALS; CHROMIUM; FATTY ACIDS, NONESTERIFIED; INSULIN RESISTANCE; LIVER; MITOCHONDRIA; RATS; REACTIVE OXYGEN SPECIES; SELENIUM; SELENOPROTEINS;

EID: 84887558484     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.10.005     Document Type: Article

References (43)

1. Bleys J., Navas-Acien A., Guallar E. Serum selenium and diabetes in U.S. adults. Diabetes Care 2007, 30:829-834.
2. Bleys J., Navas-Acien A., Stranges S., Menke A., Miller E.R., Guallar E. Serum selenium and serum lipids in US adults. Am. J. Clin. Nutr. 2008, 88:416-423.
3. Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001, 414:813-820.
4. Carmen G., Víctor S. Signalling mechanisms regulating lipolysis. Cell. Signal. 2006, 18:401-408.
5. Chen X., Scholl T.O., Leskiw M.J., Donaldson M.R., Stein T.P. Association of glutathione peroxidase activity with insulin resistance and dietary fat intake during normal pregnancy. J. Clin. Endocrinol. Metab. 2003, 88:5963-5968.
6. Goldstein B.J., Mahadev K., Wu X. Redox paradox: insulin action is facilitated by insulin-stimulated reactive oxygen species with multiple potential signaling targets. Diabetes 2005, 54:311-321.
7. Herzig S., Hedrick S., Morantte I., Koo S.H., Galimi F., Montminy M. CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma. Nature 2003, 426:190-193.
8. Houstis N., Rosen E.D., Lander E.S. Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature 2006, 440:944-948.
9. International Diabetes Federation Diabetes Atlas 2009, IDF Executive Office, Brussels. 4th ed.
10. Kljai K., Runje R. Selenium and glycogen levels in diabetic patients. Biol. Trace Elem. Res. 2001, 83:223-229.
11. Kryukov G.V., Castellano S., Novoselov S.V., Lobanov A.V., Zehtab O., Guigo R., Gladyshev V.N. Characterization of mammalian selenoproteomes. Science 2003, 300:1439-1443.
12. Laclaustra M., Stranges S., Navas-Acien A., Ordovas J.M., Guallar E. Serum selenium and serum lipids in US adults: National Health and Nutrition Examination Survey (NHANES) 2003-2004. Atherosclerosis 2010, 210:643-648.
13. Leclercq I.A., Da Silva Morais A., Schroyen B., Van Hul N., Geerts A. Insulin resistance in hepatocytes and sinusoidal liver cells: mechanisms and consequences. J. Hepatol. 2007, 47:142-156.
14. Loh K., Deng H., Fukushima A., Cai X., Boivin B., Galic S., Bruce C., Shields B.J., Skiba B., Ooms L.M., Stepto N., Wu B., Mitchell C.A., Tonks N.K., Watt M.J., Febbraio M.A., Crack P.J., Andrikopoulos S., Tiganis T. Reactive oxygen species enhance insulin sensitivity. Cell Metab. 2009, 10:260-272.
15. 2 and plays an integral role in insulin signal transduction. Mol. Cell. Biol. 2004, 24:1844-1854.
16. Mahadev K., Wu X., Zilbering A., Zhu L., Todd J., Lawrence R., Goldstein B.J. Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes. J. Biol. Chem. 2001, 276:48662.
17. Mahadev K., Zilbering A., Zhu L., Goldstein B.J. Insulin-stimulated hydrogen peroxide reversibly inhibits proteintyrosine phosphatase 1B in vivo and enhances the early insulin action cascade. J. Biol. Chem. 2001, 276:21938-21942.
18. Mao J., Teng W. The relationship between selenoprotein p and glucose metabolism in experimental studies. Nutrients 2013, 5:1937-1948.
19. McClung J.P., Roneker C.A., Mu W., Lisk D.J., Langlais P., Liu F., Lei X.G. Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:8852-8857.
20. Misu H., Takamura T., Takayama H., Hayashi H., Matsuzawa-Nagata N., Kurita S., Ishikura K., Ando H., Takeshita Y., Ota T., Sakurai M., Yamashita T., Mizukoshi E., Yamashita T., Honda M., Miyamoto K., Kubota T., Kubota N., Kadowaki T., Kim H.J., Lee I.K., Minokoshi Y., Saito Y., Takahashi K., Yamada Y., Takakura N., Kaneko S. A liver-derived secretory protein, selenoprotein P, causes insulin resistance. Cell Metab. 2010, 12:483-495.
21. Nakamura S., Takamura T., Matsuzawa-Nagata N., Takayama H., Misu H., Noda H., Nabemoto S., Kurita S., Ota T., Ando H., Miyamoto K., Kaneko S. Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria. J. Biol. Chem. 2009, 284:14809-14818.
22. Park K., Rimm E.B., Siscovick D.S., Spiegelman D., Manson J.E., Morris J.S., Hu F.B., Mozaffarian D. Toenail selenium and incidence of type 2 diabetes in U.S. men and women. Diabetes Care 2012, 35:1544-1551.
23. Rosca M.G., Vazquez E.J., Chen Q., Kerner J., Kern T.S., Hoppel C.L. Oxidation of fatty acids is the source of increased mitochondrial reactive oxygen species production in kidney cortical tubules in early diabetes. Diabetes 2012, 61:2074-2083.
24. Spiegelman B.M. PPAR-gamma: adipogenic regulator and thiazolidinedione receptor. Diabetes 1998, 47:507-514.
25. Stallings D., Vincent J.B. Chromium. A case study in how not to perform nutritional research. Curr. Topics Nutraceut. Res. 2006, 4:89-112.
26. Steinbrenner H., Alili L., Bilgic E., Sies H., Brenneisen P. Involvement of selenoprotein P in protection of human astrocytes from oxidative damage. Free Radic. Biol. Med. 2006, 40:1513-1523.
27. Steinbrenner H., Bilgic E., Alili L., Sies H., Brenneisen P. Selenoprotein P protects endothelial cells from oxidative damage by stimulation of glutathione peroxidase expression and activity. Free Radic. Res. 2006, 40:936-943.
28. Steinbrenner H., Sies H. Protection against reactive oxygen species by selenoproteins. Biochim. Biophys. Acta 2009, 1790:1478-1485.
29. Stranges S., Galletti F., Farinaro E., D'Elia L., Russo O., Iacone R., Capasso C., Carginale V., De Luca V., Della V.E., Cappuccio F.P., Strazzullo P. Associations of selenium status with cardiometabolic risk factors: an 8-year follow-up analysis of the Olivetti Heart study. Atherosclerosis 2011, 217:274-278.
30. Stranges S., Laclaustra M., Ji C., Cappuccio F.P., Navas-Acien A., Ordovas J.M., Rayman M., Guallar E. Higher selenium status is associated with adverse blood lipid profile in British adults. J. Nutr. 2010, 140:81-87.
31. Stranges S., Marshall J.R., Natarajan R., Donahue R.P., Trevisan M., Combs G.F., Cappuccio F.P., Ceriello A., Reid M.E. Effects of long-term selenium supplementation on the incidence of type 2 diabetes: a randomized trial. Ann. Intern. Med. 2007, 147:217-223.
32. Stranges S., Sieri S., Vinceti M., Grioni S., Guallar E., Laclaustra M., Muti P., Berrino F., Krogh V. A prospective study of dietary selenium intake and risk of type 2 diabetes. BMC Public Health 2010, 10:564.
33. Tuman R.W., Doisy R.J. Metabolic effects of the glucose tolerance factor (GTF) in normal and genetically diabetic mice. Diabetes 1977, 26:820-826.
34. Wang X., Gu C., He W., Ye X., Chen H., Zhang X., Hai C. Glucose oxidase induces insulin resistance via influencing multiple targets in vitro and in vivo: the central role of oxidative stress. Biochimie 2012, 94:1017-1705.
35. Wang X., Hai C.X. ROS acts as a double-edged sword in the pathogenesis of type 2 diabetes mellitus: is Nrf2 a potential target for the treatment?. Mini-Rev. Med. Chem. 2011, 11:1082-1092.
36. Wang X., Tao L., Hai C.X. Redox-regulating role of insulin: the essence of insulin effect. Mol. Cell. Endocrinol. 2011, 349:111-127.
37. Wang X., Wu H., Chen H., Liu R., Liu J., Zhang T., Yu W., Hai C. Does insulin bolster antioxidant defenses via the extracellular signal-regulated kinases-protein kinase B-nuclear factor erythroid 2 p45-related factor 2 pathway?. Antioxid. Redox Signal. 2012, 16:1061-1070.
38. Whanger P., Vendeland S., Park Y.C., Xia Y. Metabolism of subtoxic levels of selenium in animals and humans. Ann. Clin. Lab. Sci. 1996, 26:99-113.
39. Wild S., Roglic G., Green A., Sicree R., King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004, 27:1047-1053.
40. Yang S.J., Hwang S.Y., Choi H.Y., Yoo H.J., Seo J.A., Kim S.G., Kim N.H., Baik S.H., Choi D.S., Choi K.M. Serum selenoprotein P levels in patients with type 2 diabetes and prediabetes: implications for insulin resistance, inflammation, and atherosclerosis. J. Clin. Endocrinol. Metab. 2011, 96:1325-1329.
41. Yang Y., Li N., Yu J., Zhang K., Wu S., Gao X. Auditory changes caused by chromium and antagonistic effects of zinc or selenium. J. Otolaryngol. Ophthal. Shandong Univ. 2011, 25:37-40.
42. Zeng M.S., Li X., Liu Y., Zhao H., Zhou J.C., Li K., Huang J.Q., Sun L.H., Tang J.Y., Xia X.J., Wang K.N., Lei X.G. A high-selenium diet induces insulin resistance in gestating rats and their offspring. Free Radic. Biol. Med. 2012, 52:1335-1342.
43. Zu L., Jiang H., He J., Xu C., Pu S., Liu M., Xu G. Salicylate blocks lipolytic actions of tumor necrosis factor-alpha in primary rat adipocytes. Mol. Pharmacol. 2008, 73:215-223.