-
1
-
-
82255183165
-
Postfertilization autophagy of spermorganelles prevents paternal mitochondrial DNA transmission
-
Al Rawi, S., Louvet-Vallee, S., Djeddi, A., Sachse, M., Culetto, E., Hajjar, C., Boyd, L., Legouis, R. and Galy, V. (2011).Postfertilization autophagy of spermorganelles prevents paternal mitochondrial DNA transmission. Science 334, 1144-1147.
-
(2011)
Science
, vol.334
, pp. 1144-1147
-
-
Al Rawi, S.1
Louvet-Vallee, S.2
Djeddi, A.3
Sachse, M.4
Culetto, E.5
Hajjar, C.6
Boyd, L.7
Legouis, R.8
Galy, V.9
-
2
-
-
85021716115
-
Aryl hydrocarbon receptor inhibition promotes hematolymphoid development from human pluripotent stem cells
-
Angelos, M. G., Ruh, P. N., Webber, B. R., Blum, R. H., Ryan, C. D., Bendzick, L., Shim, S., Yingst, A. M., Tufa, D. M., Verneris, M. R. et al. (2017). Aryl hydrocarbon receptor inhibition promotes hematolymphoid development from human pluripotent stem cells. Blood 129, 3428-3439.
-
(2017)
Blood
, vol.129
, pp. 3428-3439
-
-
Angelos, M. G.1
Ruh, P. N.2
Webber, B. R.3
Blum, R. H.4
Ryan, C. D.5
Bendzick, L.6
Shim, S.7
Yingst, A. M.8
Tufa, D. M.9
Verneris, M. R.10
-
3
-
-
85020255453
-
The mitochondrial respiratory chain is essential for haematopoietic stem cell function
-
Anso, E., Weinberg, S. E., Diebold, L. P., Thompson, B. J., Malinge, S., Schumacker, P. T., Liu, X., Zhang, Y., Shao, Z., Steadman, M. et al. (2017). The mitochondrial respiratory chain is essential for haematopoietic stem cell function. Nat. Cell Biol. 19, 614-625.
-
(2017)
Nat. Cell Biol
, vol.19
, pp. 614-625
-
-
Anso, E.1
Weinberg, S. E.2
Diebold, L. P.3
Thompson, B. J.4
Malinge, S.5
Schumacker, P. T.6
Liu, X.7
Zhang, Y.8
Shao, Z.9
Steadman, M.10
-
4
-
-
77951021307
-
Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells
-
Armstrong, L., Tilgner, K., Saretzki, G., Atkinson, S. P., Stojkovic, M., Moreno, R., Przyborski, S. and Lako, M. (2010). Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells. Stem Cells 28, 661-673.
-
(2010)
Stem Cells
, vol.28
, pp. 661-673
-
-
Armstrong, L.1
Tilgner, K.2
Saretzki, G.3
Atkinson, S. P.4
Stojkovic, M.5
Moreno, R.6
Przyborski, S.7
Lako, M.8
-
5
-
-
84871005673
-
The pathways of mitophagy for quality control and clearance of mitochondria
-
Ashrafi, G. and Schwarz, T. L. (2013). The pathways of mitophagy for quality control and clearance of mitochondria. Cell Death Differ. 20, 31-42.
-
(2013)
Cell Death Differ
, vol.20
, pp. 31-42
-
-
Ashrafi, G.1
Schwarz, T. L.2
-
6
-
-
85014852166
-
Autophagy, a key mechanism of oncogenesis and resistance in leukemia
-
Auberger, P. and Puissant, A. (2017). Autophagy, a key mechanism of oncogenesis and resistance in leukemia. Blood 129, 547-552.
-
(2017)
Blood
, vol.129
, pp. 547-552
-
-
Auberger, P.1
Puissant, A.2
-
7
-
-
84884558125
-
Unravelling cancer stem cell potential
-
Beck, B. and Blanpain, C. (2013). Unravelling cancer stem cell potential. Nat. Rev. Cancer 13, 727-738.
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 727-738
-
-
Beck, B.1
Blanpain, C.2
-
8
-
-
79953681887
-
Small-molecule regulators of human stem cell self-renewal
-
Bouchez, L. C., Boitano, A. E., de Lichtervelde, L., Romeo, R., Cooke, M. P. and Schultz, P. G. (2011). Small-molecule regulators of human stem cell self-renewal. Chembiochem 12, 854-857.
-
(2011)
Chembiochem
, vol.12
, pp. 854-857
-
-
Bouchez, L. C.1
Boitano, A. E.2
de Lichtervelde, L.3
Romeo, R.4
Cooke, M. P.5
Schultz, P. G.6
-
9
-
-
19944434059
-
Inhibition of macroautophagy triggers apoptosis
-
Boya, P., Gonzalez-Polo, R.-A., Casares, N., Perfettini, J., Dessen, P., Larochette, N., Metivier, D., Meley, D., Souquere, S., Yoshimori, T. et al. (2005). Inhibition of macroautophagy triggers apoptosis. Mol. Cell. Biol. 25, 1025-1040.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 1025-1040
-
-
Boya, P.1
Gonzalez-Polo, R.-A.2
Casares, N.3
Perfettini, J.4
Dessen, P.5
Larochette, N.6
Metivier, D.7
Meley, D.8
Souquere, S.9
Yoshimori, T.10
-
10
-
-
84880376355
-
Emerging regulation and functions of autophagy
-
Boya, P., Reggiori, F. and Codogno, P. (2013). Emerging regulation and functions of autophagy. Nat. Cell Biol. 15, 713-720.
-
(2013)
Nat. Cell Biol
, vol.15
, pp. 713-720
-
-
Boya, P.1
Reggiori, F.2
Codogno, P.3
-
11
-
-
84994115512
-
Autophagy in the eye: development, degeneration, and aging
-
Boya, P., Esteban-Martínez, L., Serrano-Puebla, A., Gomez-Sintes, R. and Villarejo-Zori, B. (2016). Autophagy in the eye: development, degeneration, and aging. Prog. Retin. Eye Res. 55, 206-245.
-
(2016)
Prog. Retin. Eye Res
, vol.55
, pp. 206-245
-
-
Boya, P.1
Esteban-Martínez, L.2
Serrano-Puebla, A.3
Gomez-Sintes, R.4
Villarejo-Zori, B.5
-
12
-
-
84870945375
-
Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system
-
Buckley, S. M., Aranda-Orgilles, B., Strikoudis, A., Apostolou, E., Loizou, E., Moran-Crusio, K., Farnsworth, C. L., Koller, A. A., Dasgupta, R., Silva, J. C. et al. (2012). Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system. Cell Stem Cell 11, 783-798.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 783-798
-
-
Buckley, S. M.1
Aranda-Orgilles, B.2
Strikoudis, A.3
Apostolou, E.4
Loizou, E.5
Moran-Crusio, K.6
Farnsworth, C. L.7
Koller, A. A.8
Dasgupta, R.9
Silva, J. C.10
-
13
-
-
84860614281
-
Short-term calorie restriction enhances skeletal muscle stem cell function
-
Cerletti, M., Jang, Y. C., Finley, L. W., Haigis, M. C. and Wagers, A. J. (2012). Short-term calorie restriction enhances skeletal muscle stem cell function. Cell Stem Cell 10, 515-519.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 515-519
-
-
Cerletti, M.1
Jang, Y. C.2
Finley, L. W.3
Haigis, M. C.4
Wagers, A. J.5
-
14
-
-
80052819789
-
Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells
-
Chen, T., Shen, L., Yu, J., Wan, H., Guo, A., Chen, J., Long, Y., Zhao, J. and Pei, G. (2011). Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells. Aging Cell 10, 908-911.
-
(2011)
Aging Cell
, vol.10
, pp. 908-911
-
-
Chen, T.1
Shen, L.2
Yu, J.3
Wan, H.4
Guo, A.5
Chen, J.6
Long, Y.7
Zhao, J.8
Pei, G.9
-
15
-
-
84962476246
-
Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model
-
Chen, S., Wang, C., Yeo, S., Liang, C.-C., Okamoto, T., Sun, S., Wen, J. and Guan, J.-L. (2016). Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model. Genes Dev. 30, 856-869.
-
(2016)
Genes Dev
, vol.30
, pp. 856-869
-
-
Chen, S.1
Wang, C.2
Yeo, S.3
Liang, C.-C.4
Okamoto, T.5
Sun, S.6
Wen, J.7
Guan, J.-L.8
-
16
-
-
84890848364
-
Autophagy genes coordinate with the class II PI/PtdIns 3-kinase PIKI-1 to regulate apoptotic cell clearance in C. elegans
-
Cheng, S., Wu, Y., Lu, Q., Yan, J., Zhang, H. and Wang, X. (2013). Autophagy genes coordinate with the class II PI/PtdIns 3-kinase PIKI-1 to regulate apoptotic cell clearance in C. elegans. Autophagy 9, 2022-2032.
-
(2013)
Autophagy
, vol.9
, pp. 2022-2032
-
-
Cheng, S.1
Wu, Y.2
Lu, Q.3
Yan, J.4
Zhang, H.5
Wang, X.6
-
17
-
-
84894601452
-
Autophagy regulates homeostasis of pluripotency-associated proteins in hESCs
-
Cho, Y.-H., Han, K.-M., Kim, D., Lee, J., Lee, S.-H., Choi, K.-W., Kim, J. and Han, Y.-M. (2014). Autophagy regulates homeostasis of pluripotency-associated proteins in hESCs. Stem Cells 32, 424-435.
-
(2014)
Stem Cells
, vol.32
, pp. 424-435
-
-
Cho, Y.-H.1
Han, K.-M.2
Kim, D.3
Lee, J.4
Lee, S.-H.5
Choi, K.-W.6
Kim, J.7
Han, Y.-M.8
-
18
-
-
84942329160
-
Calpain determines the propensity of adult hippocampal neural stem cells to autophagic cell death following insulin withdrawal
-
Chung, K. M., Park, H., Jung, S., Ha, S., Yoo, S.-J., Woo, H., Lee, H. J., Kim, S. W., Kim, E.-K., Moon, C. et al. (2015). Calpain determines the propensity of adult hippocampal neural stem cells to autophagic cell death following insulin withdrawal. Stem Cells 33, 3052-3064.
-
(2015)
Stem Cells
, vol.33
, pp. 3052-3064
-
-
Chung, K. M.1
Park, H.2
Jung, S.3
Ha, S.4
Yoo, S.-J.5
Woo, H.6
Lee, H. J.7
Kim, S. W.8
Kim, E.-K.9
Moon, C.10
-
19
-
-
85006093278
-
The many faces of hematopoietic stem cell heterogeneity
-
Crisan, M. and Dzierzak, E. (2016). The many faces of hematopoietic stem cell heterogeneity. Development 143, 4571-4581.
-
(2016)
Development
, vol.143
, pp. 4571-4581
-
-
Crisan, M.1
Dzierzak, E.2
-
20
-
-
80655140436
-
Autophagy positively regulates the CD44(+) CD24(-/low) breast cancer stem-like phenotype
-
Cufi, S., Vazquez-Martin, A., Oliveras-Ferraros, C., Martin-Castillo, B., Vellon, L. and Menendez, J. A. (2011). Autophagy positively regulates the CD44(+) CD24(-/low) breast cancer stem-like phenotype. Cell Cycle 10, 3871-3885.
-
(2011)
Cell Cycle
, vol.10
, pp. 3871-3885
-
-
Cufi, S.1
Vazquez-Martin, A.2
Oliveras-Ferraros, C.3
Martin-Castillo, B.4
Vellon, L.5
Menendez, J. A.6
-
21
-
-
4143072546
-
A clean start: degradation of maternal proteins at the oocyte-to-embryo transition
-
DeRenzo, C. and Seydoux, G. (2004). A clean start: degradation of maternal proteins at the oocyte-to-embryo transition. Trends Cell Biol. 14, 420-426.
-
(2004)
Trends Cell Biol
, vol.14
, pp. 420-426
-
-
DeRenzo, C.1
Seydoux, G.2
-
22
-
-
84920463081
-
Immunologic manifestations of autophagy
-
Deretic, V., Kimura, T., Timmins, G., Moseley, P., Chauhan, S. and Mandell, M. (2015). Immunologic manifestations of autophagy. J. Clin. Invest. 125, 75-84.
-
(2015)
J. Clin. Invest
, vol.125
, pp. 75-84
-
-
Deretic, V.1
Kimura, T.2
Timmins, G.3
Moseley, P.4
Chauhan, S.5
Mandell, M.6
-
23
-
-
85017964233
-
A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer
-
de Sousa e Melo, F., Kurtova, A. V., Harnoss, J. M., Kljavin, N., Hoeck, J. D., Hung, J., Anderson, J. E., Storm, E. E., Modrusan, Z., Koeppen, H. et al. (2017). A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer. Nature 543, 676-680.
-
(2017)
Nature
, vol.543
, pp. 676-680
-
-
de Sousa e Melo, F.1
Kurtova, A. V.2
Harnoss, J. M.3
Kljavin, N.4
Hoeck, J. D.5
Hung, J.6
Anderson, J. E.7
Storm, E. E.8
Modrusan, Z.9
Koeppen, H.10
-
24
-
-
34249852766
-
Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis
-
Diwan, A., Koesters, A. G., Odley, A. M., Pushkaran, S., Baines, C. P., Spike, B. T., Daria, D., Jegga, A. G., Geiger, H., Aronow, B. J. et al. (2007). Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis. Proc. Natl. Acad. Sci. USA 104, 6794-6799.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 6794-6799
-
-
Diwan, A.1
Koesters, A. G.2
Odley, A. M.3
Pushkaran, S.4
Baines, C. P.5
Spike, B. T.6
Daria, D.7
Jegga, A. G.8
Geiger, H.9
Aronow, B. J.10
-
25
-
-
0033040497
-
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
-
Doetsch, F., Caillé, I., Lim, D. A., García-Verdugo, J. M. and Alvarez-Buylla, A. (1999). Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97, 703-716.
-
(1999)
Cell
, vol.97
, pp. 703-716
-
-
Doetsch, F.1
Caillé, I.2
Lim, D. A.3
García-Verdugo, J. M.4
Alvarez-Buylla, A.5
-
26
-
-
85012935339
-
Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors
-
Doulatov, S., Vo, L. T., Macari, E. R., Wahlster, L., Kinney, M. A., Taylor, A. M., Barragan, J., Gupta, M., McGrath, K., Lee, H. Y. et al. (2017). Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors. Sci. Transl. Med. 9, eaah5645.
-
(2017)
Sci. Transl. Med
, vol.9
, pp. eaah5645
-
-
Doulatov, S.1
Vo, L. T.2
Macari, E. R.3
Wahlster, L.4
Kinney, M. A.5
Taylor, A. M.6
Barragan, J.7
Gupta, M.8
McGrath, K.9
Lee, H. Y.10
-
27
-
-
84995467810
-
Cardioprotection and lifespan extension by the natural polyamine spermidine
-
Eisenberg, T., Abdellatif, M., Schroeder, S., Primessnig, U., Stekovic, S., Pendl, T., Harger, A., Schipke, J., Zimmermann, A., Schmidt, A. et al. (2016). Cardioprotection and lifespan extension by the natural polyamine spermidine. Nat. Med. 22, 1428-1438.
-
(2016)
Nat. Med
, vol.22
, pp. 1428-1438
-
-
Eisenberg, T.1
Abdellatif, M.2
Schroeder, S.3
Primessnig, U.4
Stekovic, S.5
Pendl, T.6
Harger, A.7
Schipke, J.8
Zimmermann, A.9
Schmidt, A.10
-
28
-
-
77956312911
-
Malignant precursor cells pre-exist in human breast DCIS and require autophagy for survival
-
Espina, V., Mariani, B. D., Gallagher, R. I., Tran, K., Banks, S., Wiedemann, J., Huryk, H., Mueller, C., Adamo, L., Deng, J. et al. (2010). Malignant precursor cells pre-exist in human breast DCIS and require autophagy for survival. PLoS ONE 5, e10240.
-
(2010)
PLoS ONE
, vol.5
, pp. e10240
-
-
Espina, V.1
Mariani, B. D.2
Gallagher, R. I.3
Tran, K.4
Banks, S.5
Wiedemann, J.6
Huryk, H.7
Mueller, C.8
Adamo, L.9
Deng, J.10
-
29
-
-
85050610406
-
BNIP3L/NIX-dependent mitophagy regulates cell differentiation via metabolic reprogramming
-
Esteban-Martínez, L. and Boya, P. (2017). BNIP3L/NIX-dependent mitophagy regulates cell differentiation via metabolic reprogramming. Autophagy 1-3.
-
(2017)
Autophagy
, pp. 1-3
-
-
Esteban-Martínez, L.1
Boya, P.2
-
30
-
-
85050743442
-
Mitophagy, metabolism, and cell fate
-
Esteban-Martínez, L., Sierra-Filardi, E. and Boya, P. (2017a). Mitophagy, metabolism, and cell fate. Mol. Cell. Oncol. 4, e1353854.
-
(2017)
Mol. Cell. Oncol
, vol.4
, pp. e1353854
-
-
Esteban-Martínez, L.1
Sierra-Filardi, E.2
Boya, P.3
-
31
-
-
85018982980
-
Programmed mitophagy is essential for the glycolytic switch during cell differentiation
-
Esteban-Martínez, L., Sierra-Filardi, E., McGreal, R. S., Salazar-Roa, M., Marino, G., Seco, E., Durand, S., Enot, D., Grana, O., Malumbres, M. et al. (2017b). Programmed mitophagy is essential for the glycolytic switch during cell differentiation. EMBO J. 36, 1688-1706.
-
(2017)
EMBO J
, vol.36
, pp. 1688-1706
-
-
Esteban-Martínez, L.1
Sierra-Filardi, E.2
McGreal, R. S.3
Salazar-Roa, M.4
Marino, G.5
Seco, E.6
Durand, S.7
Enot, D.8
Grana, O.9
Malumbres, M.10
-
32
-
-
70349592516
-
The relationship between pluripotency and mitochondrial DNA proliferation during early embryo development and embryonic stem cell differentiation
-
Facucho-Oliveira, J. M. and St John, J. C. (2009). The relationship between pluripotency and mitochondrial DNA proliferation during early embryo development and embryonic stem cell differentiation. Stem Cell Rev. 5, 140-158.
-
(2009)
Stem Cell Rev
, vol.5
, pp. 140-158
-
-
Facucho-Oliveira, J. M.1
St John, J. C.2
-
33
-
-
84907221142
-
Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell selfrenewal
-
Fares, I., Chagraoui, J., Gareau, Y., Gingras, S., Ruel, R., Mayotte, N., Csaszar, E., Knapp, D. J., Miller, P., Ngom, M. et al. (2014). Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell selfrenewal. Science 345, 1509-1512.
-
(2014)
Science
, vol.345
, pp. 1509-1512
-
-
Fares, I.1
Chagraoui, J.2
Gareau, Y.3
Gingras, S.4
Ruel, R.5
Mayotte, N.6
Csaszar, E.7
Knapp, D. J.8
Miller, P.9
Ngom, M.10
-
34
-
-
84979266136
-
Autophagy regulates satellite cell ability to regenerate normal and dystrophic muscles
-
Fiacco, E., Castagnetti, F., Bianconi, V., Madaro, L., De Bardi, M., Nazio, F., D'Amico, A., Bertini, E., Cecconi, F., Puri, P. L. et al. (2016). Autophagy regulates satellite cell ability to regenerate normal and dystrophic muscles. Cell Death Differ. 23, 1839-1849.
-
(2016)
Cell Death Differ
, vol.23
, pp. 1839-1849
-
-
Fiacco, E.1
Castagnetti, F.2
Bianconi, V.3
Madaro, L.4
De Bardi, M.5
Nazio, F.6
D'Amico, A.7
Bertini, E.8
Cecconi, F.9
Puri, P. L.10
-
35
-
-
79960945131
-
Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming
-
Folmes, C. D. L., Nelson, T. J., Martinez-Fernandez, A., Arrell, D. K., Lindor, J. Z., Dzeja, P. P., Ikeda, Y., Perez-Terzic, C. and Terzic, A. (2011). Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming. Cell Metab. 14, 264-271.
-
(2011)
Cell Metab
, vol.14
, pp. 264-271
-
-
Folmes, C. D. L.1
Nelson, T. J.2
Martinez-Fernandez, A.3
Arrell, D. K.4
Lindor, J. Z.5
Dzeja, P. P.6
Ikeda, Y.7
Perez-Terzic, C.8
Terzic, A.9
-
36
-
-
85010800524
-
The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesis
-
Fortini, P., Ferretti, C., Iorio, E., Cagnin, M., Garribba, L., Pietraforte, D., Falchi, M., Pascucci, B., Baccarini, S., Morani, F. et al. (2016). The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesis. Cell Death Dis. 7, e2168.
-
(2016)
Cell Death Dis
, vol.7
, pp. e2168
-
-
Fortini, P.1
Ferretti, C.2
Iorio, E.3
Cagnin, M.4
Garribba, L.5
Pietraforte, D.6
Falchi, M.7
Pascucci, B.8
Baccarini, S.9
Morani, F.10
-
37
-
-
84926252071
-
Autophagy in malignant transformation and cancer progression
-
Galluzzi, L., Pietrocola, F., Bravo-San Pedro, J. M., Amaravadi, R. K., Baehrecke, E. H., Cecconi, F., Codogno, P., Debnath, J., Gewirtz, D. A., Karantza, V. et al. (2015). Autophagy in malignant transformation and cancer progression. EMBO J. 34, 856-880.
-
(2015)
EMBO J
, vol.34
, pp. 856-880
-
-
Galluzzi, L.1
Pietrocola, F.2
Bravo-San Pedro, J. M.3
Amaravadi, R. K.4
Baehrecke, E. H.5
Cecconi, F.6
Codogno, P.7
Debnath, J.8
Gewirtz, D. A.9
Karantza, V.10
-
38
-
-
85020297927
-
Molecular definitions of autophagy and related processes
-
Galluzzi, L., Baehrecke, E. H., Ballabio, A., Boya, P., Bravo-San Pedro, J. M., Cecconi, F., Choi, A. M., Chu, C. T., Codogno, P., Colombo, M. I. et al. (2017a). Molecular definitions of autophagy and related processes. EMBO J. 36, 1811-1836.
-
(2017)
EMBO J
, vol.36
, pp. 1811-1836
-
-
Galluzzi, L.1
Baehrecke, E. H.2
Ballabio, A.3
Boya, P.4
Bravo-San Pedro, J. M.5
Cecconi, F.6
Choi, A. M.7
Chu, C. T.8
Codogno, P.9
Colombo, M. I.10
-
39
-
-
84995370898
-
Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy
-
Galluzzi, L., Bravo-San Pedro, J. M., Demaria, S., Formenti, S. C. and Kroemer, G. (2017b). Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy. Nat. Rev. Clin. Oncol. 14, 247-258.
-
(2017)
Nat. Rev. Clin. Oncol
, vol.14
, pp. 247-258
-
-
Galluzzi, L.1
Bravo-San Pedro, J. M.2
Demaria, S.3
Formenti, S. C.4
Kroemer, G.5
-
40
-
-
84953872755
-
Autophagy maintains stemness by preventing senescence
-
García-Prat, L., Martínez-Vicente, M., Perdiguero, E., Ortet, L., Rodríguez- Ubreva, J., Rebollo, E., Ruiz-Bonilla, V., Gutarra, S., Ballestar, E., Serrano, A. L. et al. (2016). Autophagy maintains stemness by preventing senescence. Nature 529, 37-42.
-
(2016)
Nature
, vol.529
, pp. 37-42
-
-
García-Prat, L.1
Martínez-Vicente, M.2
Perdiguero, E.3
Ortet, L.4
Rodríguez- Ubreva, J.5
Rebollo, E.6
Ruiz-Bonilla, V.7
Gutarra, S.8
Ballestar, E.9
Serrano, A. L.10
-
41
-
-
85018300530
-
Proteostatic and metabolic control of stemness
-
Garcia-Prat, L., Sousa-Victor, P. and Munoz-Canoves, P. (2017). Proteostatic and metabolic control of stemness. Cell Stem Cell 20, 593-608.
-
(2017)
Cell Stem Cell
, vol.20
, pp. 593-608
-
-
Garcia-Prat, L.1
Sousa-Victor, P.2
Munoz-Canoves, P.3
-
42
-
-
84877584521
-
Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/ progenitor cells
-
Gong, C., Bauvy, C., Tonelli, G., Yue, W., Delomenie, C., Nicolas, V., Zhu, Y., Domergue, V., Marin-Esteban, V., Tharinger, H. et al. (2013). Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/ progenitor cells. Oncogene 32, 2261-2272.
-
(2013)
Oncogene
, vol.32
, pp. 2261-2272
-
-
Gong, C.1
Bauvy, C.2
Tonelli, G.3
Yue, W.4
Delomenie, C.5
Nicolas, V.6
Zhu, Y.7
Domergue, V.8
Marin-Esteban, V.9
Tharinger, H.10
-
43
-
-
84880893068
-
Autophagy in stem cells
-
Guan, J.-L., Simon, A. K., Prescott, M., Menendez, J. A., Liu, F., Wang, F., Wang, C., Wolvetang, E., Vazquez-Martin, A. and Zhang, J. (2013). Autophagy in stem cells. Autophagy 9, 830-849.
-
(2013)
Autophagy
, vol.9
, pp. 830-849
-
-
Guan, J.-L.1
Simon, A. K.2
Prescott, M.3
Menendez, J. A.4
Liu, F.5
Wang, F.6
Wang, C.7
Wolvetang, E.8
Vazquez-Martin, A.9
Zhang, J.10
-
44
-
-
84944446395
-
Cancer stem cells and autophagy
-
Hamaï, A., Codogno, P. and Mehrpour, M. (2014). Cancer stem cells and autophagy. J. Cancer Stem Cell Res. 2, e1005.
-
(2014)
J. Cancer Stem Cell Res
, vol.2
, pp. e1005
-
-
Hamaï, A.1
Codogno, P.2
Mehrpour, M.3
-
45
-
-
78149487692
-
Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues
-
Hanna, J. H., Saha, K. and Jaenisch, R. (2010). Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues. Cell 143, 508-525.
-
(2010)
Cell
, vol.143
, pp. 508-525
-
-
Hanna, J. H.1
Saha, K.2
Jaenisch, R.3
-
46
-
-
84871683601
-
Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency
-
Hansson, J., Rafiee, M. R., Reiland, S., Polo, J. M., Gehring, J., Okawa, S., Huber, W., Hochedlinger, K. and Krijgsveld, J. (2012). Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency. Cell Rep. 2, 1579-1592.
-
(2012)
Cell Rep
, vol.2
, pp. 1579-1592
-
-
Hansson, J.1
Rafiee, M. R.2
Reiland, S.3
Polo, J. M.4
Gehring, J.5
Okawa, S.6
Huber, W.7
Hochedlinger, K.8
Krijgsveld, J.9
-
47
-
-
84866256464
-
An elaborate regulation of Mammalian target of rapamycin activity is required for somatic cell reprogramming induced by defined transcription factors
-
He, J., Kang, L., Wu, T., Zhang, J., Wang, H., Gao, H., Zhang, Y., Huang, B., Liu, W., Kou, Z. et al. (2012). An elaborate regulation of Mammalian target of rapamycin activity is required for somatic cell reprogramming induced by defined transcription factors. Stem Cells Dev. 21, 2630-2641.
-
(2012)
Stem Cells Dev
, vol.21
, pp. 2630-2641
-
-
He, J.1
Kang, L.2
Wu, T.3
Zhang, J.4
Wang, H.5
Gao, H.6
Zhang, Y.7
Huang, B.8
Liu, W.9
Kou, Z.10
-
48
-
-
84861513958
-
Hemogenic endothelium during development and beyond
-
Hirschi, K. K. (2012). Hemogenic endothelium during development and beyond. Blood 119, 4823-4827.
-
(2012)
Blood
, vol.119
, pp. 4823-4827
-
-
Hirschi, K. K.1
-
49
-
-
85015223506
-
Autophagy maintains the metabolism and function of young and old stem cells
-
Ho, T. T., Warr, M. R., Adelman, E. R., Lansinger, O. M., Flach, J., Verovskaya, E. V., Figueroa, M. E. and Passegué, E. (2017). Autophagy maintains the metabolism and function of young and old stem cells. Nature 543, 205-210.
-
(2017)
Nature
, vol.543
, pp. 205-210
-
-
Ho, T. T.1
Warr, M. R.2
Adelman, E. R.3
Lansinger, O. M.4
Flach, J.5
Verovskaya, E. V.6
Figueroa, M. E.7
Passegué, E.8
-
50
-
-
84860633017
-
NuRD and pluripotency: a complex balancing act
-
Hu, G. and Wade, P. A. (2012). NuRD and pluripotency: a complex balancing act. Cell Stem Cell 10, 497-503.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 497-503
-
-
Hu, G.1
Wade, P. A.2
-
51
-
-
85013361356
-
Single-cell RNA sequencing highlights transcription activity of autophagy-related genes during hematopoietic stem cell formation in mouse embryos
-
Hu, Y., Huang, Y., Yi, Y., Wang, H., Liu, B., Yu, J. andWang, D. (2017). Single-cell RNA sequencing highlights transcription activity of autophagy-related genes during hematopoietic stem cell formation in mouse embryos. Autophagy 13, 770-771.
-
(2017)
Autophagy
, vol.13
, pp. 770-771
-
-
Hu, Y.1
Huang, Y.2
Yi, Y.3
Wang, H.4
Liu, B.5
Yu, J.6
andWang, D.7
-
52
-
-
84873628958
-
Autophagy genes function in apoptotic cell corpse clearance during C. elegans embryonic development
-
Huang, S., Jia, K., Wang, Y., Zhou, Z. and Levine, B. (2013). Autophagy genes function in apoptotic cell corpse clearance during C. elegans embryonic development. Autophagy 9, 138-149.
-
(2013)
Autophagy
, vol.9
, pp. 138-149
-
-
Huang, S.1
Jia, K.2
Wang, Y.3
Zhou, Z.4
Levine, B.5
-
53
-
-
85021689430
-
Mechanisms of autophagy initiation
-
Hurley, J. H. and Young, L. N. (2017). Mechanisms of autophagy initiation. Annu. Rev. Biochem. 86, 225-244.
-
(2017)
Annu. Rev. Biochem
, vol.86
, pp. 225-244
-
-
Hurley, J. H.1
Young, L. N.2
-
54
-
-
79952121979
-
Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
-
Iliopoulos, D., Hirsch, H. A., Wang, G. and Struhl, K. (2011). Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion. Proc. Natl. Acad. Sci. USA 108, 1397-1402.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 1397-1402
-
-
Iliopoulos, D.1
Hirsch, H. A.2
Wang, G.3
Struhl, K.4
-
55
-
-
84890828812
-
TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy
-
Isakson, P., Lystad, A. H., Breen, K., Koster, G., Stenmark, H. and Simonsen, A. (2013). TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy. Autophagy 9, 1955-1964.
-
(2013)
Autophagy
, vol.9
, pp. 1955-1964
-
-
Isakson, P.1
Lystad, A. H.2
Breen, K.3
Koster, G.4
Stenmark, H.5
Simonsen, A.6
-
56
-
-
84991108288
-
Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance
-
Ito, K., Turcotte, R., Cui, J., Zimmerman, S. E., Pinho, S., Mizoguchi, T., Arai, F., Runnels, J. M., Alt, C., Teruya-Feldstein, J. et al. (2016). Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance. Science 354, 1156-1160.
-
(2016)
Science
, vol.354
, pp. 1156-1160
-
-
Ito, K.1
Turcotte, R.2
Cui, J.3
Zimmerman, S. E.4
Pinho, S.5
Mizoguchi, T.6
Arai, F.7
Runnels, J. M.8
Alt, C.9
Teruya-Feldstein, J.10
-
57
-
-
84962821217
-
Primary cilium-autophagy-Nrf2 (PAN) axis activation commits human embryonic stem cells to a neuroectoderm fate
-
Jang, J., Wang, Y., Lalli, M. A., Guzman, E., Godshalk, S. E., Zhou, H. and Kosik, K. S. (2016). Primary cilium-autophagy-Nrf2 (PAN) axis activation commits human embryonic stem cells to a neuroectoderm fate. Cell 165, 410-420.
-
(2016)
Cell
, vol.165
, pp. 410-420
-
-
Jang, J.1
Wang, Y.2
Lalli, M. A.3
Guzman, E.4
Godshalk, S. E.5
Zhou, H.6
Kosik, K. S.7
-
58
-
-
78951478823
-
Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration
-
Jopling, C., Boue, S. and Izpisua Belmonte, J. C. I. (2011). Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration. Nat. Rev. Mol. Cell Biol. 12, 79-89.
-
(2011)
Nat. Rev. Mol. Cell Biol
, vol.12
, pp. 79-89
-
-
Jopling, C.1
Boue, S.2
Izpisua Belmonte, J. C. I.3
-
59
-
-
85026914572
-
Stimulation of functional neuronal regeneration from Muller glia in adult mice
-
Jorstad, N. L., Wilken, M. S., Grimes, W. N., Wohl, S. G., VandenBosch, L. S., Yoshimatsu, T., Wong, R. O., Rieke, F. and Reh, T. A. (2017). Stimulation of functional neuronal regeneration from Muller glia in adult mice. Nature 548, 103-107.
-
(2017)
Nature
, vol.548
, pp. 103-107
-
-
Jorstad, N. L.1
Wilken, M. S.2
Grimes, W. N.3
Wohl, S. G.4
VandenBosch, L. S.5
Yoshimatsu, T.6
Wong, R. O.7
Rieke, F.8
Reh, T. A.9
-
60
-
-
84887456727
-
Mitophagy in hematopoietic stem cells: the case for exploration
-
Joshi, A. and Kundu, M. (2013). Mitophagy in hematopoietic stem cells: the case for exploration. Autophagy 9, 1737-1749.
-
(2013)
Autophagy
, vol.9
, pp. 1737-1749
-
-
Joshi, A.1
Kundu, M.2
-
61
-
-
84863011357
-
Autophagy driven by a master regulator of hematopoiesis
-
Kang, Y.-A., Sanalkumar, R., O'Geen, H., Linnemann, A. K., Chang, C.-J., Bouhassira, E. E., Farnham, P. J., Keles, S. and Bresnick, E. H. (2012). Autophagy driven by a master regulator of hematopoiesis. Mol. Cell. Biol. 32, 226-239.
-
(2012)
Mol. Cell. Biol
, vol.32
, pp. 226-239
-
-
Kang, Y.-A.1
Sanalkumar, R.2
O'Geen, H.3
Linnemann, A. K.4
Chang, C.-J.5
Bouhassira, E. E.6
Farnham, P. J.7
Keles, S.8
Bresnick, E. H.9
-
62
-
-
84938072487
-
Autophagy at the crossroads of catabolism and anabolism
-
Kaur, J. and Debnath, J. (2015). Autophagy at the crossroads of catabolism and anabolism. Nat. Rev. Mol. Cell Biol. 16, 461-472.
-
(2015)
Nat. Rev. Mol. Cell Biol
, vol.16
, pp. 461-472
-
-
Kaur, J.1
Debnath, J.2
-
63
-
-
84949559900
-
Proteostasis and aging
-
Kaushik, S. and Cuervo, A. M. (2015). Proteostasis and aging. Nat. Med. 21, 1406-1415.
-
(2015)
Nat. Med
, vol.21
, pp. 1406-1415
-
-
Kaushik, S.1
Cuervo, A. M.2
-
64
-
-
84955242756
-
Ubiquitin-dependent and independent signals in selective autophagy
-
Khaminets, A., Behl, C. and Dikic, I. (2016). Ubiquitin-dependent and independent signals in selective autophagy. Trends Cell Biol. 26, 6-16.
-
(2016)
Trends Cell Biol
, vol.26
, pp. 6-16
-
-
Khaminets, A.1
Behl, C.2
Dikic, I.3
-
65
-
-
84904739356
-
Surviving change: the metabolic journey of hematopoietic stem cells
-
Kohli, L. and Passegué, E. (2014). Surviving change: the metabolic journey of hematopoietic stem cells. Trends Cell Biol. 24, 479-487.
-
(2014)
Trends Cell Biol
, vol.24
, pp. 479-487
-
-
Kohli, L.1
Passegué, E.2
-
66
-
-
33846420629
-
A high glycolytic flux supports the proliferative potential of murine embryonic stem cells
-
Kondoh, H., Lleonart, M. E., Nakashima, Y., Yokode, M., Tanaka, M., Bernard, D., Gil, J. and Beach, D. (2007). A high glycolytic flux supports the proliferative potential of murine embryonic stem cells. Antioxid. Redox Signal. 9, 293-299.
-
(2007)
Antioxid. Redox Signal
, vol.9
, pp. 293-299
-
-
Kondoh, H.1
Lleonart, M. E.2
Nakashima, Y.3
Yokode, M.4
Tanaka, M.5
Bernard, D.6
Gil, J.7
Beach, D.8
-
67
-
-
80053564250
-
Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity
-
Kuo, T.-C., Chen, C.-T., Baron, D., Onder, T. T., Loewer, S., Almeida, S., Weismann, C. M., Xu, P., Houghton, J.-M., Gao, F.-B. et al. (2011). Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity. Nat. Cell Biol. 13, 1214-1223.
-
(2011)
Nat. Cell Biol
, vol.13
, pp. 1214-1223
-
-
Kuo, T.-C.1
Chen, C.-T.2
Baron, D.3
Onder, T. T.4
Loewer, S.5
Almeida, S.6
Weismann, C. M.7
Xu, P.8
Houghton, J.-M.9
Gao, F.-B.10
-
68
-
-
84943143136
-
Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells
-
Lawson, D. A., Bhakta, N. R., Kessenbrock, K., Prummel, K. D., Yu, Y., Takai, K., Zhou, A., Eyob, H., Balakrishnan, S., Wang, C.-Y. et al. (2015). Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells. Nature 526, 131-135.
-
(2015)
Nature
, vol.526
, pp. 131-135
-
-
Lawson, D. A.1
Bhakta, N. R.2
Kessenbrock, K.3
Prummel, K. D.4
Yu, Y.5
Takai, K.6
Zhou, A.7
Eyob, H.8
Balakrishnan, S.9
Wang, C.-Y.10
-
69
-
-
84939804206
-
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
-
Lazarou, M., Sliter, D. A., Kane, L. A., Sarraf, S. A., Wang, C., Burman, J. L., Sideris, D. P., Fogel, A. I. and Youle, R. J. (2015). The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy. Nature 524, 309-314.
-
(2015)
Nature
, vol.524
, pp. 309-314
-
-
Lazarou, M.1
Sliter, D. A.2
Kane, L. A.3
Sarraf, S. A.4
Wang, C.5
Burman, J. L.6
Sideris, D. P.7
Fogel, A. I.8
Youle, R. J.9
-
70
-
-
78650968492
-
Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/ Akt-dependant manner
-
Le Belle, J. E., Orozco, N. M., Paucar, A. A., Saxe, J. P., Mottahedeh, J., Pyle, A. D., Wu, H. and Kornblum, H. I. (2011). Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/ Akt-dependant manner. Cell Stem Cell 8, 59-71.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 59-71
-
-
Le Belle, J. E.1
Orozco, N. M.2
Paucar, A. A.3
Saxe, J. P.4
Mottahedeh, J.5
Pyle, A. D.6
Wu, H.7
Kornblum, H. I.8
-
71
-
-
84979516652
-
Embryonic stem cells: a novel paradigm to study proteostasis?
-
Lee, H. J., Gutierrez-Garcia, R. and Vilchez, D. (2017). Embryonic stem cells: a novel paradigm to study proteostasis? FEBS J. 284, 391-398.
-
(2017)
FEBS J
, vol.284
, pp. 391-398
-
-
Lee, H. J.1
Gutierrez-Garcia, R.2
Vilchez, D.3
-
72
-
-
84860311580
-
Autophagy genes function sequentially to promote apoptotic cell corpse degradation in the engulfing cell
-
Li, W., Zou, W., Yang, Y., Chai, Y., Chen, B., Cheng, S., Tian, D., Wang, X., Vale, R. D. and Ou, G. (2012). Autophagy genes function sequentially to promote apoptotic cell corpse degradation in the engulfing cell. J. Cell Biol. 197, 27-35.
-
(2012)
J. Cell Biol
, vol.197
, pp. 27-35
-
-
Li, W.1
Zou, W.2
Yang, Y.3
Chai, Y.4
Chen, B.5
Cheng, S.6
Tian, D.7
Wang, X.8
Vale, R. D.9
Ou, G.10
-
73
-
-
84960804623
-
EVA1A/TMEM166 regulates embryonic neurogenesis by autophagy
-
Li, M., Lu, G., Hu, J., Shen, X., Ju, J., Gao, Y., Qu, L., Xia, Y., Chen, Y. and Bai, Y. (2016). EVA1A/TMEM166 regulates embryonic neurogenesis by autophagy. Stem Cell Reports 6, 396-410.
-
(2016)
Stem Cell Reports
, vol.6
, pp. 396-410
-
-
Li, M.1
Lu, G.2
Hu, J.3
Shen, X.4
Ju, J.5
Gao, Y.6
Qu, L.7
Xia, Y.8
Chen, Y.9
Bai, Y.10
-
74
-
-
84938676930
-
Autophagy in cancer stem/progenitor cells
-
Lin, Y.-H., Huang, Y.-C., Chen, L.-H. and Chu, P.-M. (2015). Autophagy in cancer stem/progenitor cells. Cancer Chemother. Pharmacol. 75, 879-886.
-
(2015)
Cancer Chemother. Pharmacol
, vol.75
, pp. 879-886
-
-
Lin, Y.-H.1
Huang, Y.-C.2
Chen, L.-H.3
Chu, P.-M.4
-
75
-
-
78649689953
-
FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells
-
Liu, F., Lee, J. Y., Wei, H., Tanabe, O., Engel, J. D., Morrison, S. J. and Guan, J.-L. (2010). FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells. Blood 116, 4806-4814.
-
(2010)
Blood
, vol.116
, pp. 4806-4814
-
-
Liu, F.1
Lee, J. Y.2
Wei, H.3
Tanabe, O.4
Engel, J. D.5
Morrison, S. J.6
Guan, J.-L.7
-
76
-
-
84984706225
-
ATG3-dependent autophagy mediates mitochondrial homeostasis in pluripotency acquirement and maintenance
-
Liu, K., Zhao, Q., Liu, P., Cao, J., Gong, J., Wang, C., Wang, W., Li, X., Sun, H., Zhang, C. et al. (2016). ATG3-dependent autophagy mediates mitochondrial homeostasis in pluripotency acquirement and maintenance. Autophagy 12, 2000-2008.
-
(2016)
Autophagy
, vol.12
, pp. 2000-2008
-
-
Liu, K.1
Zhao, Q.2
Liu, P.3
Cao, J.4
Gong, J.5
Wang, C.6
Wang, W.7
Li, X.8
Sun, H.9
Zhang, C.10
-
77
-
-
85029218681
-
High autophagic flux guards ESC identity through coordinating autophagy machinery gene program by FOXO1
-
Liu, P., Liu, K., Gu, H., Wang, W., Gong, J., Zhu, Y., Zhao, Q., Cao, J., Han, C., Gao, F. et al. (2017). High autophagic flux guards ESC identity through coordinating autophagy machinery gene program by FOXO1. Cell Death Differ. 24, 1672-1680.
-
(2017)
Cell Death Differ
, vol.24
, pp. 1672-1680
-
-
Liu, P.1
Liu, K.2
Gu, H.3
Wang, W.4
Gong, J.5
Zhu, Y.6
Zhao, Q.7
Cao, J.8
Han, C.9
Gao, F.10
-
78
-
-
84905907209
-
The crucial role of Atg5 in cortical neurogenesis during early brain development
-
Lv, X., Jiang, H., Li, B., Liang, Q., Wang, S., Zhao, Q. and Jiao, J. (2014). The crucial role of Atg5 in cortical neurogenesis during early brain development. Sci. Rep. 4, 6010.
-
(2014)
Sci. Rep
, vol.4
, pp. 6010
-
-
Lv, X.1
Jiang, H.2
Li, B.3
Liang, Q.4
Wang, S.5
Zhao, Q.6
Jiao, J.7
-
79
-
-
84946478936
-
Atg5-independent autophagy regulates mitochondrial clearance and is essential for iPSC reprogramming
-
Ma, T., Li, J., Xu, Y., Yu, C., Xu, T., Wang, H., Liu, K., Cao, N., Nie, B.-M., Zhu, S.-Y. et al. (2015). Atg5-independent autophagy regulates mitochondrial clearance and is essential for iPSC reprogramming. Nat. Cell Biol. 17, 1379-1387.
-
(2015)
Nat. Cell Biol
, vol.17
, pp. 1379-1387
-
-
Ma, T.1
Li, J.2
Xu, Y.3
Yu, C.4
Xu, T.5
Wang, H.6
Liu, K.7
Cao, N.8
Nie, B.-M.9
Zhu, S.-Y.10
-
80
-
-
84920421073
-
Essential role for autophagy in life span extension
-
Madeo, F., Zimmermann, A., Maiuri, M. C. and Kroemer, G. (2015). Essential role for autophagy in life span extension. J. Clin. Invest. 125, 85-93.
-
(2015)
J. Clin. Invest
, vol.125
, pp. 85-93
-
-
Madeo, F.1
Zimmermann, A.2
Maiuri, M. C.3
Kroemer, G.4
-
81
-
-
84995538137
-
TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation
-
Mandell, M. A., Jain, A., Kumar, S., Castleman, M. J., Anwar, T., Eskelinen, E.-L., Johansen, T., Prekeris, R. and Deretic, V. (2016). TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation. J. Cell Sci. 129, 3562-3573.
-
(2016)
J. Cell Sci
, vol.129
, pp. 3562-3573
-
-
Mandell, M. A.1
Jain, A.2
Kumar, S.3
Castleman, M. J.4
Anwar, T.5
Eskelinen, E.-L.6
Johansen, T.7
Prekeris, R.8
Deretic, V.9
-
82
-
-
85011025989
-
The role of autophagy in the crosstalk between epithelial-mesenchymal transitioned tumor cells and cancer stemlike cells
-
Marcucci, F., Ghezzi, P. and Rumio, C. (2017). The role of autophagy in the crosstalk between epithelial-mesenchymal transitioned tumor cells and cancer stemlike cells. Mol. Cancer 16, 3.
-
(2017)
Mol. Cancer
, vol.16
, pp. 3
-
-
Marcucci, F.1
Ghezzi, P.2
Rumio, C.3
-
83
-
-
84955515590
-
Metastatic colonization by circulating tumour cells
-
Massagué, J. and Obenauf, A. C. (2016). Metastatic colonization by circulating tumour cells. Nature 529, 298-306.
-
(2016)
Nature
, vol.529
, pp. 298-306
-
-
Massagué, J.1
Obenauf, A. C.2
-
84
-
-
84928034921
-
Autophagy supports breast cancer stem cell maintenance by regulating IL6 secretion
-
Maycotte, P., Jones, K. L., Goodall, M. L., Thorburn, J. and Thorburn, A. (2015). Autophagy supports breast cancer stem cell maintenance by regulating IL6 secretion. Mol. Cancer Res. 13, 651-658.
-
(2015)
Mol. Cancer Res
, vol.13
, pp. 651-658
-
-
Maycotte, P.1
Jones, K. L.2
Goodall, M. L.3
Thorburn, J.4
Thorburn, A.5
-
85
-
-
47249164452
-
The autophagic machinery is necessary for removal of cell corpses from the developing retinal neuroepithelium
-
Mellén, M. A., de la Rosa, E. J. and Boya, P. (2008). The autophagic machinery is necessary for removal of cell corpses from the developing retinal neuroepithelium. Cell Death Differ. 15, 1279-1290.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1279-1290
-
-
Mellén, M. A.1
de la Rosa, E. J.2
Boya, P.3
-
86
-
-
70349646889
-
Autophagy is not universally required for phosphatidyl-serine exposure and apoptotic cell engulfment during neural development
-
Mellén, M. A., de la Rosa, E. J. and Boya, P. (2009). Autophagy is not universally required for phosphatidyl-serine exposure and apoptotic cell engulfment during neural development. Autophagy 5, 964-972.
-
(2009)
Autophagy
, vol.5
, pp. 964-972
-
-
Mellén, M. A.1
de la Rosa, E. J.2
Boya, P.3
-
87
-
-
80655140600
-
mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to stem cell renewal and aging
-
Menendez, J. A., Vellon, L., Oliveras-Ferraros, C., Cufí, S. and Vazquez-Martin, A. (2011). mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to stem cell renewal and aging. Cell Cycle 10, 3658-3677.
-
(2011)
Cell Cycle
, vol.10
, pp. 3658-3677
-
-
Menendez, J. A.1
Vellon, L.2
Oliveras-Ferraros, C.3
Cufí, S.4
Vazquez-Martin, A.5
-
88
-
-
85014799386
-
Autophagy and neurodegeneration: pathogenic mechanisms and therapeutic opportunities
-
Menzies, F. M., Fleming, A., Caricasole, A., Bento, C. F., Andrews, S. P., Ashkenazi, A., Fü llgrabe, J., Jackson, A., Jimenez Sanchez, M., Karabiyik, C. et al. (2017). Autophagy and neurodegeneration: pathogenic mechanisms and therapeutic opportunities. Neuron 93, 1015-1034.
-
(2017)
Neuron
, vol.93
, pp. 1015-1034
-
-
Menzies, F. M.1
Fleming, A.2
Caricasole, A.3
Bento, C. F.4
Andrews, S. P.5
Ashkenazi, A.6
Fü llgrabe, J.7
Jackson, A.8
Jimenez Sanchez, M.9
Karabiyik, C.10
-
89
-
-
81055144784
-
Autophagy: renovation of cells and tissues
-
Mizushima, N. and Komatsu, M. (2011). Autophagy: renovation of cells and tissues. Cell 147, 728-741.
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
90
-
-
77956416339
-
Autophagy in mammalian development and differentiation
-
Mizushima, N. and Levine, B. (2010). Autophagy in mammalian development and differentiation. Nat. Cell Biol. 12, 823-830.
-
(2010)
Nat. Cell Biol
, vol.12
, pp. 823-830
-
-
Mizushima, N.1
Levine, B.2
-
91
-
-
1542283812
-
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
-
Mizushima, N., Yamamoto, A., Matsui, M., Yoshimori, T. and Ohsumi, Y. (2004). In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol. Biol. Cell 15, 1101-1111.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 1101-1111
-
-
Mizushima, N.1
Yamamoto, A.2
Matsui, M.3
Yoshimori, T.4
Ohsumi, Y.5
-
92
-
-
84939874676
-
MicroRNA-34a modulates neural stem cell differentiation by regulating expression of synaptic and autophagic proteins
-
Morgado, A. L., Xavier, J. M., Dionisio, P. A., Ribeiro, M. F. C., Dias, R. B., Sebastião, A. M., Solá, S. and Rodrigues, C. M. (2015). MicroRNA-34a modulates neural stem cell differentiation by regulating expression of synaptic and autophagic proteins. Mol. Neurobiol. 51, 1168-1183.
-
(2015)
Mol. Neurobiol
, vol.51
, pp. 1168-1183
-
-
Morgado, A. L.1
Xavier, J. M.2
Dionisio, P. A.3
Ribeiro, M. F. C.4
Dias, R. B.5
Sebastião, A. M.6
Solá, S.7
Rodrigues, C. M.8
-
93
-
-
79952728102
-
The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance
-
Mortensen, M., Soilleux, E. J., Djordjevic, G., Tripp, R., Lutteropp, M., Sadighi- Akha, E., Stranks, A. J., Glanville, J., Knight, S., Jacobsen, S.-E. et al. (2011). The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance. J. Exp. Med. 208, 455-467.
-
(2011)
J. Exp. Med
, vol.208
, pp. 455-467
-
-
Mortensen, M.1
Soilleux, E. J.2
Djordjevic, G.3
Tripp, R.4
Lutteropp, M.5
Sadighi- Akha, E.6
Stranks, A. J.7
Glanville, J.8
Knight, S.9
Jacobsen, S.-E.10
-
94
-
-
84940720812
-
Mitochondrial autophagy: origins, significance, and role of BNIP3 and NIX
-
Ney, P. A. (2015). Mitochondrial autophagy: origins, significance, and role of BNIP3 and NIX. Biochim. Biophys. Acta 1853, 2775-2783.
-
(2015)
Biochim. Biophys. Acta
, vol.1853
, pp. 2775-2783
-
-
Ney, P. A.1
-
95
-
-
84924251561
-
Autophagy in cancer stem cells: a potential link between chemoresistance, recurrence, and metastasis
-
Ojha, R., Bhattacharyya, S. and Singh, S. K. (2015). Autophagy in cancer stem cells: a potential link between chemoresistance, recurrence, and metastasis. BioResearch Open Access 4, 97-108.
-
(2015)
BioResearch Open Access
, vol.4
, pp. 97-108
-
-
Ojha, R.1
Bhattacharyya, S.2
Singh, S. K.3
-
96
-
-
70350497348
-
FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis
-
Paik, J.-H., Ding, Z., Narurkar, R., Ramkissoon, S., Muller, F., Kamoun, W. S., Chae, S.-S., Zheng, H., Ying, H., Mahoney, J. et al. (2009). FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis. Cell Stem Cell 5, 540-553.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 540-553
-
-
Paik, J.-H.1
Ding, Z.2
Narurkar, R.3
Ramkissoon, S.4
Muller, F.5
Kamoun, W. S.6
Chae, S.-S.7
Zheng, H.8
Ying, H.9
Mahoney, J.10
-
97
-
-
0030438734
-
The adult rat hippocampus contains primordial neural stem cells
-
Palmer, T. D., Takahashi, J. and Gage, F. H. (1997). The adult rat hippocampus contains primordial neural stem cells. Mol. Cell. Neurosci. 8, 389-404.
-
(1997)
Mol. Cell. Neurosci
, vol.8
, pp. 389-404
-
-
Palmer, T. D.1
Takahashi, J.2
Gage, F. H.3
-
98
-
-
84874698634
-
Autophagic control of cell 'stemness'
-
Pan, H., Cai, N., Li, M., Liu, G.-H. and Izpisua Belmonte, J. C. (2013). Autophagic control of cell 'stemness'. EMBO Mol. Med. 5, 327-331.
-
(2013)
EMBO Mol. Med
, vol.5
, pp. 327-331
-
-
Pan, H.1
Cai, N.2
Li, M.3
Liu, G.-H.4
Izpisua Belmonte, J. C.5
-
99
-
-
85016165255
-
Targeting metastasis-initiating cells through the fatty acid receptor CD36
-
Pascual, G., Avgustinova, A., Mejetta, S., Martín, M., Castellanos, A., Attolini, C. S.-O., Berenguer, A., Prats, N., Toll, A., Hueto, J. A. et al. (2017). Targeting metastasis-initiating cells through the fatty acid receptor CD36. Nature 541, 41-45.
-
(2017)
Nature
, vol.541
, pp. 41-45
-
-
Pascual, G.1
Avgustinova, A.2
Mejetta, S.3
Martín, M.4
Castellanos, A.5
Attolini, C. S.-O.6
Berenguer, A.7
Prats, N.8
Toll, A.9
Hueto, J. A.10
-
100
-
-
84903768676
-
Tackling the cancer stem cells - what challenges do they pose?
-
Pattabiraman, D. R. and Weinberg, R. A. (2014). Tackling the cancer stem cells - what challenges do they pose? Nat. Rev. Drug Discov. 13, 497-512.
-
(2014)
Nat. Rev. Drug Discov
, vol.13
, pp. 497-512
-
-
Pattabiraman, D. R.1
Weinberg, R. A.2
-
101
-
-
77951002352
-
The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells
-
Prigione, A., Fauler, B., Lurz, R., Lehrach, H. and Adjaye, J. (2010). The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells. Stem Cells 28, 721-733.
-
(2010)
Stem Cells
, vol.28
, pp. 721-733
-
-
Prigione, A.1
Fauler, B.2
Lurz, R.3
Lehrach, H.4
Adjaye, J.5
-
102
-
-
33847404337
-
Autophagy gene-dependent clearance of apoptotic cells during embryonic development
-
Qu, X., Zou, Z., Sun, Q., Luby-Phelps, K., Cheng, P., Hogan, R. N., Gilpin, C. and Levine, B. (2007). Autophagy gene-dependent clearance of apoptotic cells during embryonic development. Cell 128, 931-946.
-
(2007)
Cell
, vol.128
, pp. 931-946
-
-
Qu, X.1
Zou, Z.2
Sun, Q.3
Luby-Phelps, K.4
Cheng, P.5
Hogan, R. N.6
Gilpin, C.7
Levine, B.8
-
103
-
-
84885619736
-
Deterministic direct reprogramming of somatic cells to pluripotency
-
Rais, Y., Zviran, A., Geula, S., Gafni, O., Chomsky, E., Viukov, S., Mansour, A. A., Caspi, I., Krupalnik, V., Zerbib, M. et al. (2013). Deterministic direct reprogramming of somatic cells to pluripotency. Nature 502, 65-70.
-
(2013)
Nature
, vol.502
, pp. 65-70
-
-
Rais, Y.1
Zviran, A.2
Geula, S.3
Gafni, O.4
Chomsky, E.5
Viukov, S.6
Mansour, A. A.7
Caspi, I.8
Krupalnik, V.9
Zerbib, M.10
-
104
-
-
70350506802
-
FoxO3 regulates neural stem cell homeostasis
-
Renault, V. M., Rafalski, V. A., Morgan, A. A., Salih, D. A. M., Brett, J. O., Webb, A. E., Villeda, S. A., Thekkat, P. U., Guillerey, C., Denko, N. C. et al. (2009). FoxO3 regulates neural stem cell homeostasis. Cell Stem Cell 5, 527-539.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 527-539
-
-
Renault, V. M.1
Rafalski, V. A.2
Morgan, A. A.3
Salih, D. A. M.4
Brett, J. O.5
Webb, A. E.6
Villeda, S. A.7
Thekkat, P. U.8
Guillerey, C.9
Denko, N. C.10
-
105
-
-
84964844342
-
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells
-
Rentas, S., Holzapfel, N., Belew, M. S., Pratt, G., Voisin, V., Wilhelm, B. T., Bader, G. D., Yeo, G. W. and Hope, K. J. (2016). Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells. Nature 532, 508-511.
-
(2016)
Nature
, vol.532
, pp. 508-511
-
-
Rentas, S.1
Holzapfel, N.2
Belew, M. S.3
Pratt, G.4
Voisin, V.5
Wilhelm, B. T.6
Bader, G. D.7
Yeo, G. W.8
Hope, K. J.9
-
106
-
-
85182136117
-
Autophagy dictates metabolism and differentiation of inflammatory immune cells
-
Riffelmacher, T., Richter, F. C. and Simon, A. K. (2017). Autophagy dictates metabolism and differentiation of inflammatory immune cells. Autophagy 1-8.
-
(2017)
Autophagy
, pp. 1-8
-
-
Riffelmacher, T.1
Richter, F. C.2
Simon, A. K.3
-
107
-
-
85000919223
-
Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1
-
Rojansky, R., Cha, M. Y. and Chan, D. C. (2016). Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1. Elife 5, e17896.
-
(2016)
Elife
, vol.5
, pp. e17896
-
-
Rojansky, R.1
Cha, M. Y.2
Chan, D. C.3
-
108
-
-
84942319012
-
Concise review: quiescence in adult stem cells: biological significance and relevance to tissue regeneration
-
Rumman, M., Dhawan, J. and Kassem, M. (2015). Concise review: quiescence in adult stem cells: biological significance and relevance to tissue regeneration. Stem Cells 33, 2903-2912.
-
(2015)
Stem Cells
, vol.33
, pp. 2903-2912
-
-
Rumman, M.1
Dhawan, J.2
Kassem, M.3
-
109
-
-
47049100413
-
Essential role for Nix in autophagic maturation of erythroid cells
-
Sandoval, H., Thiagarajan, P., Dasgupta, S. K., Schumacher, A., Prchal, J. T., Chen, M. and Wang, J. (2008). Essential role for Nix in autophagic maturation of erythroid cells. Nature 454, 232-235.
-
(2008)
Nature
, vol.454
, pp. 232-235
-
-
Sandoval, H.1
Thiagarajan, P.2
Dasgupta, S. K.3
Schumacher, A.4
Prchal, J. T.5
Chen, M.6
Wang, J.7
-
110
-
-
84864882073
-
FOXOphagy path to inducing stress resistance and cell survival
-
Sandri, M. (2012). FOXOphagy path to inducing stress resistance and cell survival. Nat. Cell Biol. 14, 786-788.
-
(2012)
Nat. Cell Biol
, vol.14
, pp. 786-788
-
-
Sandri, M.1
-
111
-
-
34248994604
-
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models
-
Sarkar, S., Perlstein, E. O., Imarisio, S., Pineau, S., Cordenier, A., Maglathlin, R. L., Webster, J. A., Lewis, T. A., O'Kane, C. J., Schreiber, S. L. et al. (2007). Small molecules enhance autophagy and reduce toxicity in Huntington's disease models. Nat. Chem. Biol. 3, 331-338.
-
(2007)
Nat. Chem. Biol
, vol.3
, pp. 331-338
-
-
Sarkar, S.1
Perlstein, E. O.2
Imarisio, S.3
Pineau, S.4
Cordenier, A.5
Maglathlin, R. L.6
Webster, J. A.7
Lewis, T. A.8
O'Kane, C. J.9
Schreiber, S. L.10
-
112
-
-
82255192465
-
Degradation of paternal mitochondria by fertilizationtriggered autophagy in C. elegans embryos
-
Sato, M. and Sato, K. (2011). Degradation of paternal mitochondria by fertilizationtriggered autophagy in C. elegans embryos. Science 334, 1141-1144.
-
(2011)
Science
, vol.334
, pp. 1141-1144
-
-
Sato, M.1
Sato, K.2
-
113
-
-
82955207614
-
Cell differentiation: midbody remnants-junk or fate factors?
-
Schink, K. O. and Stenmark, H. (2011). Cell differentiation: midbody remnants-junk or fate factors? Curr. Biol. 21, R958-R960.
-
(2011)
Curr. Biol
, vol.21
, pp. R958-R960
-
-
Schink, K. O.1
Stenmark, H.2
-
114
-
-
84901833411
-
Autophagy and human disease: emerging themes
-
Schneider, J. L. and Cuervo, A. M. (2014). Autophagy and human disease: emerging themes. Curr. Opin. Genet. Dev. 26C, 16-23.
-
(2014)
Curr. Opin. Genet. Dev
, vol.26C
, pp. 16-23
-
-
Schneider, J. L.1
Cuervo, A. M.2
-
115
-
-
84868007565
-
Physiological roles of mitochondrial reactive oxygen species
-
Sena, L. A. and Chandel, N. S. (2012). Physiological roles of mitochondrial reactive oxygen species. Mol. Cell 48, 158-167.
-
(2012)
Mol. Cell
, vol.48
, pp. 158-167
-
-
Sena, L. A.1
Chandel, N. S.2
-
116
-
-
85015760419
-
The metabolic programming of stem cells
-
Shyh-Chang, N. and Ng, H.-H. (2017). The metabolic programming of stem cells. Genes Dev. 31, 336-346.
-
(2017)
Genes Dev
, vol.31
, pp. 336-346
-
-
Shyh-Chang, N.1
Ng, H.-H.2
-
117
-
-
84875953755
-
Stem cell metabolism in tissue development and aging
-
Shyh-Chang, N., Daley, G. Q. and Cantley, L. C. (2013). Stem cell metabolism in tissue development and aging. Development 140, 2535-2547.
-
(2013)
Development
, vol.140
, pp. 2535-2547
-
-
Shyh-Chang, N.1
Daley, G. Q.2
Cantley, L. C.3
-
118
-
-
84964528934
-
Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts
-
Sin, J., Andres, A. M., Taylor, D. J. R., Weston, T., Hiraumi, Y., Stotland, A., Kim, B. J., Huang, C., Doran, K. S. and Gottlieb, R. A. (2016). Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts. Autophagy 12, 369-380.
-
(2016)
Autophagy
, vol.12
, pp. 369-380
-
-
Sin, J.1
Andres, A. M.2
Taylor, D. J. R.3
Weston, T.4
Hiraumi, Y.5
Stotland, A.6
Kim, B. J.7
Huang, C.8
Doran, K. S.9
Gottlieb, R. A.10
-
119
-
-
84923225259
-
Tumor heterogeneity and cancer stem cell paradigm: updates in concept, controversies and clinical relevance
-
Singh, A. K., Arya, R. K., Maheshwari, S., Singh, A., Meena, S., Pandey, P., Dormond, O. and Datta, D. (2015). Tumor heterogeneity and cancer stem cell paradigm: updates in concept, controversies and clinical relevance. Int. J. Cancer 136, 1991-2000.
-
(2015)
Int. J. Cancer
, vol.136
, pp. 1991-2000
-
-
Singh, A. K.1
Arya, R. K.2
Maheshwari, S.3
Singh, A.4
Meena, S.5
Pandey, P.6
Dormond, O.7
Datta, D.8
-
120
-
-
85027496313
-
Aged stem cells reprogram their daily rhythmic functions to adapt to stress
-
e620
-
Solanas, G., Peixoto, F. O., Perdiguero, E., Jardi, M., Ruiz-Bonilla, V., Datta, D., Symeonidi, A., Castellanos, A., Welz, P. S., Caballero, J. M. et al. (2017). Aged stem cells reprogram their daily rhythmic functions to adapt to stress. Cell 170, 678-692 e620.
-
(2017)
Cell
, vol.170
, pp. 678-692
-
-
Solanas, G.1
Peixoto, F. O.2
Perdiguero, E.3
Jardi, M.4
Ruiz-Bonilla, V.5
Datta, D.6
Symeonidi, A.7
Castellanos, A.8
Welz, P. S.9
Caballero, J. M.10
-
121
-
-
84904721826
-
Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes
-
Stienstra, R., Haim, Y., Riahi, Y., Netea, M., Rudich, A. and Leibowitz, G. (2014). Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes. Diabetologia 57, 1505-1516.
-
(2014)
Diabetologia
, vol.57
, pp. 1505-1516
-
-
Stienstra, R.1
Haim, Y.2
Riahi, Y.3
Netea, M.4
Rudich, A.5
Leibowitz, G.6
-
122
-
-
33747604117
-
The analysis of mitochondria and mitochondrial DNA in human embryonic stem cells
-
St John, J. C., Amaral, A., Bowles, E., Oliveira, J. F., Lloyd, R., Freitas, M., Gray, H. L., Navara, C. S., Oliveira, G., Schatten, G. P. et al. (2006). The analysis of mitochondria and mitochondrial DNA in human embryonic stem cells. Methods Mol. Biol. 331, 347-374.
-
(2006)
Methods Mol. Biol
, vol.331
, pp. 347-374
-
-
St John, J. C.1
Amaral, A.2
Bowles, E.3
Oliveira, J. F.4
Lloyd, R.5
Freitas, M.6
Gray, H. L.7
Navara, C. S.8
Oliveira, G.9
Schatten, G. P.10
-
123
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K. and Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
124
-
-
79955377420
-
Autophagy-deficient mice develop multiple liver tumors
-
Takamura, A., Komatsu, M., Hara, T., Sakamoto, A., Kishi, C., Waguri, S., Eishi, Y., Hino, O., Tanaka, K. and Mizushima, N. (2011). Autophagy-deficient mice develop multiple liver tumors. Genes Dev. 25, 795-800.
-
(2011)
Genes Dev
, vol.25
, pp. 795-800
-
-
Takamura, A.1
Komatsu, M.2
Hara, T.3
Sakamoto, A.4
Kishi, C.5
Waguri, S.6
Eishi, Y.7
Hino, O.8
Tanaka, K.9
Mizushima, N.10
-
125
-
-
84887456252
-
The epigenetics of epithelial-mesenchymal plasticity in cancer
-
Tam, W. L. andWeinberg, R. A. (2013). The epigenetics of epithelial-mesenchymal plasticity in cancer. Nat. Med. 19, 1438-1449.
-
(2013)
Nat. Med
, vol.19
, pp. 1438-1449
-
-
Tam, W. L.1
andWeinberg, R. A.2
-
126
-
-
85021702696
-
Mitophagy transcriptome: mechanistic insights into polyphenol-mediated mitophagy
-
Tan, S. and Wong, E. (2017). Mitophagy transcriptome: mechanistic insights into polyphenol-mediated mitophagy. Oxid. Med. Cell. Longev. 2017, 9028435.
-
(2017)
Oxid. Med. Cell. Longev
, vol.2017
, pp. 9028435
-
-
Tan, S.1
Wong, E.2
-
127
-
-
84919343329
-
Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation
-
Tang, A. H. and Rando, T. A. (2014). Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation. EMBO J. 33, 2782-2797.
-
(2014)
EMBO J
, vol.33
, pp. 2782-2797
-
-
Tang, A. H.1
Rando, T. A.2
-
128
-
-
46849115787
-
Autophagy is essential for preimplantation development of mouse embryos
-
Tsukamoto, S., Kuma, A., Murakami, M., Kishi, C., Yamamoto, A. and Mizushima, N. (2008). Autophagy is essential for preimplantation development of mouse embryos. Science 321, 117-120.
-
(2008)
Science
, vol.321
, pp. 117-120
-
-
Tsukamoto, S.1
Kuma, A.2
Murakami, M.3
Kishi, C.4
Yamamoto, A.5
Mizushima, N.6
-
129
-
-
84897384830
-
Fluorescence-based visualization of autophagic activity predicts mouse embryo viability
-
Tsukamoto, S., Hara, T., Yamamoto, A., Kito, S., Minami, N., Kubota, T., Sato, K. and Kokubo, T. (2014). Fluorescence-based visualization of autophagic activity predicts mouse embryo viability. Sci. Rep. 4, 4533.
-
(2014)
Sci. Rep
, vol.4
, pp. 4533
-
-
Tsukamoto, S.1
Hara, T.2
Yamamoto, A.3
Kito, S.4
Minami, N.5
Kubota, T.6
Sato, K.7
Kokubo, T.8
-
130
-
-
84857345898
-
Atg5 and Ambra1 differentially modulate neurogenesis in neural stem cells
-
Vazquez, P., Arroba, A. I., Cecconi, F., de la Rosa, E. J., Boya, P. and De Pablo, F. (2012). Atg5 and Ambra1 differentially modulate neurogenesis in neural stem cells. Autophagy 8, 187-199.
-
(2012)
Autophagy
, vol.8
, pp. 187-199
-
-
Vazquez, P.1
Arroba, A. I.2
Cecconi, F.3
de la Rosa, E. J.4
Boya, P.5
De Pablo, F.6
-
131
-
-
84981488617
-
Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate
-
Vazquez-Martin, A., Van den Haute, C., Cufi, S., Corominas-Faja, B., Cuyas, E., Lopez-Bonet, E., Rodriguez-Gallego, E., Fernández-Arroyo, S., Joven, J., Baekelandt, V. et al. (2016). Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate. Aging (Albany NY) 8, 1330-1352.
-
(2016)
Aging (Albany NY)
, vol.8
, pp. 1330-1352
-
-
Vazquez-Martin, A.1
Van den Haute, C.2
Cufi, S.3
Corominas-Faja, B.4
Cuyas, E.5
Lopez-Bonet, E.6
Rodriguez-Gallego, E.7
Fernández-Arroyo, S.8
Joven, J.9
Baekelandt, V.10
-
132
-
-
84857489373
-
Autophagy in stem cell maintenance and differentiation
-
Vessoni, A. T., Muotri, A. R. and Okamoto, O. K. (2012). Autophagy in stem cell maintenance and differentiation. Stem Cells Dev. 21, 513-520.
-
(2012)
Stem Cells Dev
, vol.21
, pp. 513-520
-
-
Vessoni, A. T.1
Muotri, A. R.2
Okamoto, O. K.3
-
133
-
-
84866167976
-
Increased proteasome activity in human embryonic stem cells is regulated by PSMD11
-
Vilchez, D., Boyer, L., Morantte, I., Lutz, M., Merkwirth, C., Joyce, D., Spencer, B., Page, L., Masliah, E., Berggren, W. T. et al. (2012). Increased proteasome activity in human embryonic stem cells is regulated by PSMD11. Nature 489, 304-308.
-
(2012)
Nature
, vol.489
, pp. 304-308
-
-
Vilchez, D.1
Boyer, L.2
Morantte, I.3
Lutz, M.4
Merkwirth, C.5
Joyce, D.6
Spencer, B.7
Page, L.8
Masliah, E.9
Berggren, W. T.10
-
134
-
-
84856096512
-
Satellite cells, the engines of muscle repair
-
Wang, Y. X. and Rudnicki, M. A. (2011). Satellite cells, the engines of muscle repair. Nat. Rev. Mol. Cell Biol. 13, 127-133.
-
(2011)
Nat. Rev. Mol. Cell Biol
, vol.13
, pp. 127-133
-
-
Wang, Y. X.1
Rudnicki, M. A.2
-
135
-
-
84876893671
-
FIP200 is required for maintenance and differentiation of postnatal neural stem cells
-
Wang, C., Liang, C.-C., Bian, Z. C., Zhu, Y. and Guan, J.-L. (2013a). FIP200 is required for maintenance and differentiation of postnatal neural stem cells. Nat. Neurosci. 16, 532-542.
-
(2013)
Nat. Neurosci
, vol.16
, pp. 532-542
-
-
Wang, C.1
Liang, C.-C.2
Bian, Z. C.3
Zhu, Y.4
Guan, J.-L.5
-
136
-
-
84901349234
-
Transient activation of autophagy via Sox2-mediated suppression of mTOR is an important early step in reprogramming to pluripotency
-
Wang, S., Xia, P., Ye, B., Huang, G., Liu, J. and Fan, Z. (2013b). Transient activation of autophagy via Sox2-mediated suppression of mTOR is an important early step in reprogramming to pluripotency. Cell Stem Cell 13, 617-625.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 617-625
-
-
Wang, S.1
Xia, P.2
Ye, B.3
Huang, G.4
Liu, J.5
Fan, Z.6
-
137
-
-
84960389624
-
Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide
-
Wang, C., Chen, S., Yeo, S., Karsli-Uzunbas, G., White, E., Mizushima, N., Virgin, H. W. and Guan, J.-L. (2016a). Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide. J. Cell Biol. 212, 545-560.
-
(2016)
J. Cell Biol
, vol.212
, pp. 545-560
-
-
Wang, C.1
Chen, S.2
Yeo, S.3
Karsli-Uzunbas, G.4
White, E.5
Mizushima, N.6
Virgin, H. W.7
Guan, J.-L.8
-
138
-
-
84992189476
-
The p53 pathway controls SOX2-mediated reprogramming in the adult mouse spinal cord
-
Wang, L.-L., Su, Z., Tai, W., Zou, Y., Xu, X.-M. and Zhang, C.-L. (2016b). The p53 pathway controls SOX2-mediated reprogramming in the adult mouse spinal cord. Cell Rep. 17, 891-903.
-
(2016)
Cell Rep
, vol.17
, pp. 891-903
-
-
Wang, L.-L.1
Su, Z.2
Tai, W.3
Zou, Y.4
Xu, X.-M.5
Zhang, C.-L.6
-
139
-
-
85027286827
-
Autophagy gene FIP200 in neural progenitors non-cell autonomously controls differentiation by regulating microglia
-
Wang, C., Yeo, S., Haas, M. A. and Guan, J.-L. (2017). Autophagy gene FIP200 in neural progenitors non-cell autonomously controls differentiation by regulating microglia. J. Cell Biol. 216, 2581-2596.
-
(2017)
J. Cell Biol
, vol.216
, pp. 2581-2596
-
-
Wang, C.1
Yeo, S.2
Haas, M. A.3
Guan, J.-L.4
-
140
-
-
84874192375
-
FOXO3A directs a protective autophagy program in haematopoietic stem cells
-
Warr, M. R., Binnewies, M., Flach, J., Reynaud, D., Garg, T., Malhotra, R., Debnath, J. and Passegué, E. (2013). FOXO3A directs a protective autophagy program in haematopoietic stem cells. Nature 494, 323-327.
-
(2013)
Nature
, vol.494
, pp. 323-327
-
-
Warr, M. R.1
Binnewies, M.2
Flach, J.3
Reynaud, D.4
Garg, T.5
Malhotra, R.6
Debnath, J.7
Passegué, E.8
-
141
-
-
85076917710
-
Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia
-
Watson, A. S., Riffelmacher, T., Stranks, A., Williams, O., De Boer, J., Cain, K., MacFarlane, M., McGouran, J., Kessler, B., Khandwala, S. et al. (2015). Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia. Cell Death Discov. 1, 15008.
-
(2015)
Cell Death Discov
, vol.1
, pp. 15008
-
-
Watson, A. S.1
Riffelmacher, T.2
Stranks, A.3
Williams, O.4
De Boer, J.5
Cain, K.6
MacFarlane, M.7
McGouran, J.8
Kessler, B.9
Khandwala, S.10
-
142
-
-
84897414264
-
FOXO transcription factors: key regulators of cellular quality control
-
Webb, A. E. and Brunet, A. (2014). FOXO transcription factors: key regulators of cellular quality control. Trends Biochem. Sci. 39, 159-169.
-
(2014)
Trends Biochem. Sci
, vol.39
, pp. 159-169
-
-
Webb, A. E.1
Brunet, A.2
-
143
-
-
84920415711
-
The role for autophagy in cancer
-
White, E. (2015). The role for autophagy in cancer. J. Clin. Invest. 125, 42-46.
-
(2015)
J. Clin. Invest
, vol.125
, pp. 42-46
-
-
White, E.1
-
144
-
-
85029945778
-
Cerebellar granule cell replenishment postinjury by adaptive reprogramming of Nestin+ progenitors
-
Wojcinski, A., Lawton, A. K., Bayin, N. S., Lao, Z., Stephen, D. N. and Joyner, A. L. (2017). Cerebellar granule cell replenishment postinjury by adaptive reprogramming of Nestin+ progenitors. Nat. Neurosci. 20, 1361-1370.
-
(2017)
Nat. Neurosci
, vol.20
, pp. 1361-1370
-
-
Wojcinski, A.1
Lawton, A. K.2
Bayin, N. S.3
Lao, Z.4
Stephen, D. N.5
Joyner, A. L.6
-
145
-
-
84957598643
-
Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis
-
Wu, X., Fleming, A., Ricketts, T., Pavel, M., Virgin, H., Menzies, F. M. and Rubinsztein, D. C. (2016). Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis. Nat. Commun. 7, 10533.
-
(2016)
Nat. Commun
, vol.7
, pp. 10533
-
-
Wu, X.1
Fleming, A.2
Ricketts, T.3
Pavel, M.4
Virgin, H.5
Menzies, F. M.6
Rubinsztein, D. C.7
-
146
-
-
85014783987
-
Knockout of Atg5 delays the maturation and reduces the survival of adultgenerated neurons in the hippocampus
-
Xi, Y., Dhaliwal, J. S., Ceizar, M., Vaculik, M., Kumar, K. L. and Lagace, D. C. (2016). Knockout of Atg5 delays the maturation and reduces the survival of adultgenerated neurons in the hippocampus. Cell Death Dis. 7, e2127.
-
(2016)
Cell Death Dis
, vol.7
, pp. e2127
-
-
Xi, Y.1
Dhaliwal, J. S.2
Ceizar, M.3
Vaculik, M.4
Kumar, K. L.5
Lagace, D. C.6
-
147
-
-
85027528273
-
BNIP3L-dependent mitophagy accounts for mitochondrial clearance during three factors induced somatic cell reprogramming
-
Xiang, G., Yang, L., Long, Q., Chen, K., Tang, H., Wu, Y., Liu, Z., Zhou, Y., Qi, J., Zheng, L. et al. (2017). BNIP3L-dependent mitophagy accounts for mitochondrial clearance during three factors induced somatic cell reprogramming. Autophagy 13, 1543-1555.
-
(2017)
Autophagy
, vol.13
, pp. 1543-1555
-
-
Xiang, G.1
Yang, L.2
Long, Q.3
Chen, K.4
Tang, H.5
Wu, Y.6
Liu, Z.7
Zhou, Y.8
Qi, J.9
Zheng, L.10
-
148
-
-
84906222771
-
Fertilizationinduced autophagy in mouse embryos is independent of mTORC1
-
Yamamoto, A., Mizushima, N. and Tsukamoto, S. (2014). Fertilizationinduced autophagy in mouse embryos is independent of mTORC1. Biol. Reprod. 91, 7.
-
(2014)
Biol. Reprod
, vol.91
, pp. 7
-
-
Yamamoto, A.1
Mizushima, N.2
Tsukamoto, S.3
-
149
-
-
84862528505
-
Induced pluripotent stem cells: past, present, and future
-
Yamanaka, S. (2012). Induced pluripotent stem cells: past, present, and future. Cell Stem Cell 10, 678-684.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 678-684
-
-
Yamanaka, S.1
-
150
-
-
77953466536
-
Nuclear reprogramming to a pluripotent state by three approaches
-
Yamanaka, S. and Blau, H.M. (2010). Nuclear reprogramming to a pluripotent state by three approaches. Nature 465, 704-712.
-
(2010)
Nature
, vol.465
, pp. 704-712
-
-
Yamanaka, S.1
Blau, H.M.2
-
151
-
-
84921792662
-
The autophagy regulators Ambra1 and Beclin 1 are required for adult neurogenesis in the brain subventricular zone
-
Yazdankhah, M., Farioli-Vecchioli, S., Tonchev, A. B., Stoykova, A. and Cecconi, F. (2014). The autophagy regulators Ambra1 and Beclin 1 are required for adult neurogenesis in the brain subventricular zone. Cell Death Dis. 5, e1403.
-
(2014)
Cell Death Dis
, vol.5
, pp. e1403
-
-
Yazdankhah, M.1
Farioli-Vecchioli, S.2
Tonchev, A. B.3
Stoykova, A.4
Cecconi, F.5
-
152
-
-
55049111460
-
Autophagic death of adult hippocampal neural stem cells following insulin withdrawal
-
Yu, S.-W., Baek, S.-H., Brennan, R. T., Bradley, C. J., Park, S. K., Lee, Y. S., Jun, E. J., Lookingland, K. J., Kim, E.-K., Lee, H. et al. (2008). Autophagic death of adult hippocampal neural stem cells following insulin withdrawal. Stem Cells 26, 2602-2610.
-
(2008)
Stem Cells
, vol.26
, pp. 2602-2610
-
-
Yu, S.-W.1
Baek, S.-H.2
Brennan, R. T.3
Bradley, C. J.4
Park, S. K.5
Lee, Y. S.6
Jun, E. J.7
Lookingland, K. J.8
Kim, E.-K.9
Lee, H.10
-
153
-
-
84872037830
-
Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation
-
Yu, W.-M., Liu, X., Shen, J., Jovanovic, O., Pohl, E. E., Gerson, S. L., Finkel, T., Broxmeyer, H. E. and Qu, C.-K. (2013). Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation. Cell Stem Cell 12, 62-74.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 62-74
-
-
Yu, W.-M.1
Liu, X.2
Shen, J.3
Jovanovic, O.4
Pohl, E. E.5
Gerson, S. L.6
Finkel, T.7
Broxmeyer, H. E.8
Qu, C.-K.9
-
154
-
-
84877332222
-
Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance
-
Yue, W., Hamaï, A., Tonelli, G., Bauvy, C., Nicolas, V., Tharinger, H., Codogno, P. and Mehrpour, M. (2013). Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance. Autophagy 9, 714-729.
-
(2013)
Autophagy
, vol.9
, pp. 714-729
-
-
Yue, W.1
Hamaï, A.2
Tonelli, G.3
Bauvy, C.4
Nicolas, V.5
Tharinger, H.6
Codogno, P.7
Mehrpour, M.8
-
155
-
-
80052490840
-
FOXO1 is an essential regulator of pluripotency in human embryonic stem cells
-
Zhang, X., Yalcin, S., Lee, D.-F., Yeh, T.-Y. J., Lee, S.-M., Su, J., Mungamuri, S. K., Rimmelé, P., Kennedy, M., Sellers, R. et al. (2011). FOXO1 is an essential regulator of pluripotency in human embryonic stem cells. Nat. Cell Biol. 13, 1092-1099.
-
(2011)
Nat. Cell Biol
, vol.13
, pp. 1092-1099
-
-
Zhang, X.1
Yalcin, S.2
Lee, D.-F.3
Yeh, T.-Y. J.4
Lee, S.-M.5
Su, J.6
Mungamuri, S. K.7
Rimmelé, P.8
Kennedy, M.9
Sellers, R.10
-
156
-
-
84978197362
-
Autophagy, inflammation, and immunity: a troika governing cancer and its treatment
-
Zhong, Z., Sanchez-Lopez, E. and Karin, M. (2016). Autophagy, inflammation, and immunity: a troika governing cancer and its treatment. Cell 166, 288-298.
-
(2016)
Cell
, vol.166
, pp. 288-298
-
-
Zhong, Z.1
Sanchez-Lopez, E.2
Karin, M.3
-
157
-
-
84969787245
-
Tracing haematopoietic stem cell formation at single-cell resolution
-
Zhou, F., Li, X., Wang, W., Zhu, P., Zhou, J., He, W., Ding, M., Xiong, F., Zheng, X., Li, Z. et al. (2016). Tracing haematopoietic stem cell formation at single-cell resolution. Nature 533, 487-492.
-
(2016)
Nature
, vol.533
, pp. 487-492
-
-
Zhou, F.1
Li, X.2
Wang, W.3
Zhu, P.4
Zhou, J.5
He, W.6
Ding, M.7
Xiong, F.8
Zheng, X.9
Li, Z.10
|