Malignant Precursor Cells Pre-Exist in Human Breast DCIS and Require Autophagy for Survival

PLoS ONE

Volumn 5, Issue 4, 2010, Pages

  Espina, Virginia ^a   Mariani, Brian D ^b   Gallagher, Rosa I ^a   Tran, Khoa ^b   Banks, Stacey ^c   Wiedemann, Joy ^c   Huryk, Heather ^c   Mueller, Claudius ^a   Adamo, Luana ^a,d   Deng, Jianghong ^a   Petricoin III, Emanuel F ^a   Pastore, Lucia ^c   Zaman, Syed ^c   Menezes, Geetha ^c   Mize, James ^c   Johal, Jasbir ^c   Edmiston, Kirsten ^c   Liotta, Lance A ^a  

^a GEORGE MASON UNIVERSITY   (United States)

^b GENETICS AND IVF INSTITUTE   (United States)

^c INOVA FAIRFAX HOSPITAL   (United States)

^d Istituto Oncologico Del Mediterraneo   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 5; CHLOROQUINE; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CANCER STEM CELL; CARCINOGENICITY; CELL INVASION; CELL MIGRATION; CELL STRUCTURE; CELL SURVIVAL; CHROMOSOME 1; CHROMOSOME 13; CHROMOSOME 17; CHROMOSOME 5; CHROMOSOME 6; CHROMOSOME 8; CONTROLLED STUDY; COPY NUMBER VARIATION; CYTOGENETICS; EPITHELIUM CELL; EX VIVO STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INTRADUCTAL CARCINOMA; KARYOTYPE; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; SCID MOUSE; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR SPHEROID; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; CANCER INVASION; CHROMOSOME ABERRATION; GENETICS; HUMAN GENOME; MOUSE MUTANT; PATHOLOGY; TRANSPLANTATION; TUMOR CELL CULTURE; XENOGRAFT;

MUS;

ANIMALS; AUTOPHAGY; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CELL SURVIVAL; CHROMOSOME ABERRATIONS; GENOME, HUMAN; HUMANS; MICE; MICE, SCID; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 77956312911     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010240     Document Type: Article

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