-
1
-
-
84876341593
-
A KRAB/KAP1-miRNA cascade regulates erythropoiesis through stage-specific control of mitophagy
-
Barde, I., Rauwel, B., Marin-Florez, R. M., Corsinotti, A., Laurenti, E., Verp, S., Offner, S., Marquis, J., Kapopoulou, A., Vanicek, J. et al. (2013). A KRAB/KAP1-miRNA cascade regulates erythropoiesis through stage-specific control of mitophagy. Science 340, 350-353.
-
(2013)
Science
, vol.340
, pp. 350-353
-
-
Barde, I.1
Rauwel, B.2
Marin-Florez, R.M.3
Corsinotti, A.4
Laurenti, E.5
Verp, S.6
Offner, S.7
Marquis, J.8
Kapopoulou, A.9
Vanicek, J.10
-
2
-
-
84883414890
-
The LIR motif-crucial for selective autophagy
-
Birgisdottir, A. B., Lamark, T. and Johansen, T. (2013). The LIR motif-crucial for selective autophagy. J. Cell Sci. 126, 3237-3247.
-
(2013)
J. Cell Sci
, vol.126
, pp. 3237-3247
-
-
Birgisdottir, A.B.1
Lamark, T.2
Johansen, T.3
-
3
-
-
27944504351
-
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
Bjørkøy, G., Lamark, T., Brech, A., Outzen, H., Perander, M., Øvervatn, A., Stenmark, H. and Johansen, T. (2005). p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J. Cell Biol. 171, 603-614.
-
(2005)
J. Cell Biol
, vol.171
, pp. 603-614
-
-
Bjørkøy, G.1
Lamark, T.2
Brech, A.3
Outzen, H.4
Perander, M.5
Øvervatn, A.6
Stenmark, H.7
Johansen, T.8
-
4
-
-
78651488777
-
RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly
-
Bodemann, B. O., Orvedahl, A., Cheng, T., Ram, R. R., Ou, Y.-H., Formstecher, E., Maiti, M., Hazelett, C. C., Wauson, E. M., Balakireva, M. et al. (2011). RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly. Cell 144, 253-267.
-
(2011)
Cell
, vol.144
, pp. 253-267
-
-
Bodemann, B.O.1
Orvedahl, A.2
Cheng, T.3
Ram, R.R.4
Ou, Y.-H.5
Formstecher, E.6
Maiti, M.7
Hazelett, C.C.8
Wauson, E.M.9
Balakireva, M.10
-
5
-
-
76349114046
-
Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1
-
Chang, N. C., Nguyen, M., Germain, M. and Shore, G. C. (2010). Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1. EMBO J. 29, 606-618.
-
(2010)
EMBO J
, vol.29
, pp. 606-618
-
-
Chang, N.C.1
Nguyen, M.2
Germain, M.3
Shore, G.C.4
-
6
-
-
84876090708
-
ZKSCAN3 is a master transcriptional repressor of autophagy
-
Chauhan, S., Goodwin, J. G., Chauhan, S., Manyam, G., Wang, J., Kamat, A. M. and Boyd, D. D. (2013). ZKSCAN3 is a master transcriptional repressor of autophagy. Mol. Cell 50, 16-28.
-
(2013)
Mol. Cell
, vol.50
, pp. 16-28
-
-
Chauhan, S.1
Goodwin, J.G.2
Chauhan, S.3
Manyam, G.4
Wang, J.5
Kamat, A.M.6
Boyd, D.D.7
-
7
-
-
83555168258
-
Inhibition of autophagy by TAB2 and TAB3
-
Criollo, A., Niso-Santano, M., Malik, S. A., Michaud, M., Morselli, E., Mariño, G., Lachkar, S., Arkhipenko, A. V., Harper, F., Pierron, G. et al. (2011). Inhibition of autophagy by TAB2 and TAB3. EMBO J. 30, 4908-4920.
-
(2011)
EMBO J
, vol.30
, pp. 4908-4920
-
-
Criollo, A.1
Niso-Santano, M.2
Malik, S.A.3
Michaud, M.4
Morselli, E.5
Mariño, G.6
Lachkar, S.7
Arkhipenko, A.V.8
Harper, F.9
Pierron, G.10
-
8
-
-
84938710018
-
Midbody: from cellular junk to regulator of cell polarity and cell fate
-
Dionne, L. K., Wang, X.-J. and Prekeris, R. (2015). Midbody: from cellular junk to regulator of cell polarity and cell fate. Curr. Opin. Cell Biol. 35, 51-58.
-
(2015)
Curr. Opin. Cell Biol
, vol.35
, pp. 51-58
-
-
Dionne, L.K.1
Wang, X.-J.2
Prekeris, R.3
-
9
-
-
84904575441
-
WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1
-
Dooley, H. C., Razi, M., Polson, H. E., Girardin, S. E., Wilson, M. I. and Tooze, S. A. (2014). WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1. Mol. Cell 55, 238-252.
-
(2014)
Mol. Cell
, vol.55
, pp. 238-252
-
-
Dooley, H.C.1
Razi, M.2
Polson, H.E.3
Girardin, S.E.4
Wilson, M.I.5
Tooze, S.A.6
-
10
-
-
79251587803
-
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
-
Egan, D. F., Shackelford, D. B., Mihaylova, M. M., Gelino, S., Kohnz, R. A., Mair, W., Vasquez, D. S., Joshi, A., Gwinn, D. M., Taylor, R. et al. (2011). Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science 331, 456-461.
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
Gelino, S.4
Kohnz, R.A.5
Mair, W.6
Vasquez, D.S.7
Joshi, A.8
Gwinn, D.M.9
Taylor, R.10
-
11
-
-
84856420883
-
Terf/TRIM17 stimulates degradation of kinetochore protein ZWINT and regulates cell proliferation
-
Endo, H., Ikeda, K., Urano, T., Horie-Inoue, K. and Inoue, S. (2012). Terf/TRIM17 stimulates degradation of kinetochore protein ZWINT and regulates cell proliferation. J. Biochem. 151, 139-144.
-
(2012)
J. Biochem
, vol.151
, pp. 139-144
-
-
Endo, H.1
Ikeda, K.2
Urano, T.3
Horie-Inoue, K.4
Inoue, S.5
-
12
-
-
35848962530
-
Differential interactions between Beclin 1 and Bcl-2 family members
-
Erlich, S., Mizrachy, L., Segev, O., Lindenboim, L., Zmira, O., Adi-Harel, S., Hirsch, J. A., Stein, R. and Pinkas-Kramarski, R. (2007). Differential interactions between Beclin 1 and Bcl-2 family members. Autophagy 3, 561-568.
-
(2007)
Autophagy
, vol.3
, pp. 561-568
-
-
Erlich, S.1
Mizrachy, L.2
Segev, O.3
Lindenboim, L.4
Zmira, O.5
Adi-Harel, S.6
Hirsch, J.A.7
Stein, R.8
Pinkas-Kramarski, R.9
-
13
-
-
84876476422
-
Beclin-1 is required for chromosome congression and proper outer kinetochore assembly
-
Frémont, S., Gérard, A., Galloux, M., Janvier, K., Karess, R. E. and Berlioz-Torrent, C. (2013). Beclin-1 is required for chromosome congression and proper outer kinetochore assembly. EMBO Rep. 14, 364-372.
-
(2013)
EMBO Rep
, vol.14
, pp. 364-372
-
-
Frémont, S.1
Gérard, A.2
Galloux, M.3
Janvier, K.4
Karess, R.E.5
Berlioz-Torrent, C.6
-
14
-
-
84943199868
-
Cell death by autophagy: emerging molecular mechanisms and implications for cancer therapy
-
Fulda, S. and Kö gel, D. (2015). Cell death by autophagy: emerging molecular mechanisms and implications for cancer therapy. Oncogene 34, 5105-5113.
-
(2015)
Oncogene
, vol.34
, pp. 5105-5113
-
-
Fulda, S.1
Kögel, D.2
-
15
-
-
78751621004
-
MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner
-
Germain, M., Nguyen, A. P., Le Grand, J. N., Arbour, N., Vanderluit, J. L., Park, D. S., Opferman, J. T. and Slack, R. S. (2011). MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner. EMBO J. 30, 395-407.
-
(2011)
EMBO J
, vol.30
, pp. 395-407
-
-
Germain, M.1
Nguyen, A.P.2
Le Grand, J.N.3
Arbour, N.4
Vanderluit, J.L.5
Park, D.S.6
Opferman, J.T.7
Slack, R.S.8
-
16
-
-
84899131967
-
Autophagy in antimicrobial immunity
-
Gomes, L. C. and Dikic, I. (2014). Autophagy in antimicrobial immunity. Mol. Cell 54, 224-233.
-
(2014)
Mol. Cell
, vol.54
, pp. 224-233
-
-
Gomes, L.C.1
Dikic, I.2
-
17
-
-
84960968603
-
TRIM5alpha degradation via autophagy is not required for retroviral restriction
-
Imam, S., Talley, S., Nelson, R. S., Dharan, A., O'connor, C., Hope, T. J. and Campbell, E. M. (2016). TRIM5alpha degradation via autophagy is not required for retroviral restriction. J. Virol. 90, 3400-3410.
-
(2016)
J. Virol
, vol.90
, pp. 3400-3410
-
-
Imam, S.1
Talley, S.2
Nelson, R.S.3
Dharan, A.4
O'connor, C.5
Hope, T.J.6
Campbell, E.M.7
-
18
-
-
84890828812
-
TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy
-
Isakson, P., Lystad, A. H., Breen, K., Koster, G., Stenmark, H. and Simonsen, A. (2013). TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy. Autophagy 9, 1955-1964.
-
(2013)
Autophagy
, vol.9
, pp. 1955-1964
-
-
Isakson, P.1
Lystad, A.H.2
Breen, K.3
Koster, G.4
Stenmark, H.5
Simonsen, A.6
-
19
-
-
79952355107
-
Selective autophagy mediated by autophagic adapter proteins
-
Johansen, T. and Lamark, T. (2011). Selective autophagy mediated by autophagic adapter proteins. Autophagy 7, 279-296.
-
(2011)
Autophagy
, vol.7
, pp. 279-296
-
-
Johansen, T.1
Lamark, T.2
-
20
-
-
84954129051
-
p62/SQSTM1 functions as a signaling hub and an autophagy adaptor
-
Katsuragi, Y., Ichimura, Y. and Komatsu, M. (2015). p62/SQSTM1 functions as a signaling hub and an autophagy adaptor. FEBS J. 282, 4672-4678.
-
(2015)
FEBS J
, vol.282
, pp. 4672-4678
-
-
Katsuragi, Y.1
Ichimura, Y.2
Komatsu, M.3
-
21
-
-
84934449989
-
Regulation of endoplasmic reticulum turnover by selective autophagy
-
Khaminets, A., Heinrich, T., Mari, M., Grumati, P., Huebner, A. K., Akutsu, M., Liebmann, L., Stolz, A., Nietzsche, S., Koch, N. et al. (2015). Regulation of endoplasmic reticulum turnover by selective autophagy. Nature 522, 354-358.
-
(2015)
Nature
, vol.522
, pp. 354-358
-
-
Khaminets, A.1
Heinrich, T.2
Mari, M.3
Grumati, P.4
Huebner, A.K.5
Akutsu, M.6
Liebmann, L.7
Stolz, A.8
Nietzsche, S.9
Koch, N.10
-
22
-
-
0035809160
-
Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae
-
Kihara, A., Noda, T., Ishihara, N. and Ohsumi, Y. (2001). Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J. Cell Biol. 152, 519-530.
-
(2001)
J. Cell Biol
, vol.152
, pp. 519-530
-
-
Kihara, A.1
Noda, T.2
Ishihara, N.3
Ohsumi, Y.4
-
23
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim, J., Kundu, M., Viollet, B. and Guan, K.-L. (2011). AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat. Cell Biol. 13, 132-141.
-
(2011)
Nat. Cell Biol
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.-L.4
-
24
-
-
84872586081
-
Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy
-
Kim, J., Kim, Y. C., Fang, C., Russell, R. C., Kim, J. H., Fan, W., Liu, R., Zhong, Q. and Guan, K.-L. (2013). Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy. Cell 152, 290-303.
-
(2013)
Cell
, vol.152
, pp. 290-303
-
-
Kim, J.1
Kim, Y.C.2
Fang, C.3
Russell, R.C.4
Kim, J.H.5
Fan, W.6
Liu, R.7
Zhong, Q.8
Guan, K.-L.9
-
25
-
-
84960432718
-
TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity
-
Kimura, T., Jain, A., Choi, S.W., Mandell, M. A., Schroder, K., Johansen, T. and Deretic, V. (2015). TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity. J. Cell Biol. 210, 973-989.
-
(2015)
J. Cell Biol
, vol.210
, pp. 973-989
-
-
Kimura, T.1
Jain, A.2
Choi, S.W.3
Mandell, M.A.4
Schroder, K.5
Johansen, T.6
Deretic, V.7
-
26
-
-
84960354182
-
Precision autophagy directed by receptor regulators-emerging examples within the TRIM family
-
Kimura, T., Mandell, M. and Deretic, V. (2016). Precision autophagy directed by receptor regulators-emerging examples within the TRIM family. J. Cell Sci. 129, 881-891.
-
(2016)
J. Cell Sci
, vol.129
, pp. 881-891
-
-
Kimura, T.1
Mandell, M.2
Deretic, V.3
-
27
-
-
85013763791
-
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
-
Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K. et al. (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12, 1-222.
-
(2016)
Autophagy
, vol.12
, pp. 1-222
-
-
Klionsky, D.J.1
Abdelmohsen, K.2
Abe, A.3
Abedin, M.J.4
Abeliovich, H.5
Acevedo Arozena, A.6
Adachi, H.7
Adams, C.M.8
Adams, P.D.9
Adeli, K.10
-
28
-
-
80053564250
-
Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity
-
Kuo, T.-C., Chen, C.-T., Baron, D., Onder, T. T., Loewer, S., Almeida, S., Weismann, C. M., Xu, P., Houghton, J.-M., Gao, F.-B. et al. (2011). Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity. Nat. Cell Biol. 13, 1214-1223.
-
(2011)
Nat. Cell Biol
, vol.13
, pp. 1214-1223
-
-
Kuo, T.-C.1
Chen, C.-T.2
Baron, D.3
Onder, T.T.4
Loewer, S.5
Almeida, S.6
Weismann, C.M.7
Xu, P.8
Houghton, J.-M.9
Gao, F.-B.10
-
29
-
-
67649585835
-
Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages
-
Kyei, G. B., Dinkins, C., Davis, A. S., Roberts, E., Singh, S. B., Dong, C., Wu, L., Kominami, E., Ueno, T., Yamamoto, A. et al. (2009). Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages. J. Cell Biol. 186, 255-268.
-
(2009)
J. Cell Biol
, vol.186
, pp. 255-268
-
-
Kyei, G.B.1
Dinkins, C.2
Davis, A.S.3
Roberts, E.4
Singh, S.B.5
Dong, C.6
Wu, L.7
Kominami, E.8
Ueno, T.9
Yamamoto, A.10
-
30
-
-
84939804206
-
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
-
Lazarou, M., Sliter, D. A., Kane, L. A., Sarraf, S. A., Wang, C., Burman, J. L., Sideris, D. P., Fogel, A. I. and Youle, R. J. (2015). The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy. Nature 524, 309-314.
-
(2015)
Nature
, vol.524
, pp. 309-314
-
-
Lazarou, M.1
Sliter, D.A.2
Kane, L.A.3
Sarraf, S.A.4
Wang, C.5
Burman, J.L.6
Sideris, D.P.7
Fogel, A.I.8
Youle, R.J.9
-
31
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang, X. H., Jackson, S., Seaman, M., Brown, K., Kempkes, B., Hibshoosh, H. and Levine, B. (1999). Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402, 672-676.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
32
-
-
84902125387
-
Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak
-
Lindqvist, L. M., Heinlein, M., Huang, D. C. S. and Vaux, D. L. (2014). Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak. Proc. Natl. Acad. Sci. USA 111, 8512-8517.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 8512-8517
-
-
Lindqvist, L.M.1
Heinlein, M.2
Huang, D.C.S.3
Vaux, D.L.4
-
33
-
-
84872288551
-
Trim17-mediated ubiquitination and degradation of Mcl-1 initiate apoptosis in neurons
-
Magiera, M. M., Mora, S., Mojsa, B., Robbins, I., Lassot, I. and Desagher, S. (2013). Trim17-mediated ubiquitination and degradation of Mcl-1 initiate apoptosis in neurons. Cell Death Differ. 20, 281-292.
-
(2013)
Cell Death Differ
, vol.20
, pp. 281-292
-
-
Magiera, M.M.1
Mora, S.2
Mojsa, B.3
Robbins, I.4
Lassot, I.5
Desagher, S.6
-
34
-
-
84907599058
-
TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition
-
Mandell, M. A., Jain, A., Arko-Mensah, J., Chauhan, S., Kimura, T., Dinkins, C., Silvestri, G., Mü nch, J., Kirchhoff, F., Simonsen, A. et al. (2014). TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition. Dev. Cell 30, 394-409.
-
(2014)
Dev. Cell
, vol.30
, pp. 394-409
-
-
Mandell, M.A.1
Jain, A.2
Arko-Mensah, J.3
Chauhan, S.4
Kimura, T.5
Dinkins, C.6
Silvestri, G.7
Münch, J.8
Kirchhoff, F.9
Simonsen, A.10
-
35
-
-
64049086758
-
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
-
Matsunaga, K., Saitoh, T., Tabata, K., Omori, H., Satoh, T., Kurotori, N., Maejima, I., Shirahama-Noda, K., Ichimura, T., Isobe, T. et al. (2009). Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Nat. Cell Biol. 11, 385-396.
-
(2009)
Nat. Cell Biol
, vol.11
, pp. 385-396
-
-
Matsunaga, K.1
Saitoh, T.2
Tabata, K.3
Omori, H.4
Satoh, T.5
Kurotori, N.6
Maejima, I.7
Shirahama-Noda, K.8
Ichimura, T.9
Isobe, T.10
-
36
-
-
81055144784
-
Autophagy: renovation of cells and tissues
-
Mizushima, N. and Komatsu, M. (2011). Autophagy: renovation of cells and tissues. Cell 147, 728-741.
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
37
-
-
80054025654
-
The role of atg proteins in autophagosome formation
-
Mizushima, N., Yoshimori, T. and Ohsumi, Y. (2011). The role of atg proteins in autophagosome formation. Annu. Rev. Cell Dev. Biol. 27, 107-132.
-
(2011)
Annu. Rev. Cell Dev. Biol
, vol.27
, pp. 107-132
-
-
Mizushima, N.1
Yoshimori, T.2
Ohsumi, Y.3
-
38
-
-
77955427514
-
Downregulation of active IKK beta by Ro52-mediated autophagy
-
Niida, M., Tanaka, M. and Kamitani, T. (2010). Downregulation of active IKK beta by Ro52-mediated autophagy. Mol. Immunol. 47, 2378-2387.
-
(2010)
Mol. Immunol
, vol.47
, pp. 2378-2387
-
-
Niida, M.1
Tanaka, M.2
Kamitani, T.3
-
39
-
-
53049102656
-
The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function
-
Obara, K., Sekito, T., Niimi, K. and Ohsumi, Y. (2008). The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function. J. Biol. Chem. 283, 23972-23980.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 23972-23980
-
-
Obara, K.1
Sekito, T.2
Niimi, K.3
Ohsumi, Y.4
-
40
-
-
84885661260
-
Functional interaction between autophagy and ciliogenesis
-
Pampliega, O., Orhon, I., Patel, B., Sridhar, S., Díaz-CARRETERO, A., Beau, I., Codogno, P., Satir, B. H., Satir, P. and Cuervo, A. M. (2013). Functional interaction between autophagy and ciliogenesis. Nature 502, 194-200.
-
(2013)
Nature
, vol.502
, pp. 194-200
-
-
Pampliega, O.1
Orhon, I.2
Patel, B.3
Sridhar, S.4
Díaz-Carretero, A.5
Beau, I.6
Codogno, P.7
Satir, B.H.8
Satir, P.9
Cuervo, A.M.10
-
41
-
-
84959490134
-
TRIM21 ubiquitylates SQSTM1/p62 and suppresses protein sequestration to regulate redox homeostasis
-
Pan, J.-A., Sun, Y., Jiang, Y.-P., Bott, A. J., Jaber, N., Dou, Z., Yang, B., Chen, J.-S., Catanzaro, J. M., Du, C. et al. (2016). TRIM21 ubiquitylates SQSTM1/p62 and suppresses protein sequestration to regulate redox homeostasis. Mol. Cell 61, 720-733.
-
(2016)
Mol. Cell
, vol.61
, pp. 720-733
-
-
Pan, J.-A.1
Sun, Y.2
Jiang, Y.-P.3
Bott, A.J.4
Jaber, N.5
Dou, Z.6
Yang, B.7
Chen, J.-S.8
Catanzaro, J.M.9
Du, C.10
-
42
-
-
34548259958
-
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
-
Pankiv, S., Clausen, T. H., Lamark, T., Brech, A., Bruun, J.-A., Outzen, H., Øvervatn, A., Bjørkøy, G. and Johansen, T. (2007). p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J. Biol. Chem. 282, 24131-24145.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 24131-24145
-
-
Pankiv, S.1
Clausen, T.H.2
Lamark, T.3
Brech, A.4
Bruun, J.-A.5
Outzen, H.6
Øvervatn, A.7
Bjørkøy, G.8
Johansen, T.9
-
43
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
Pattingre, S., Tassa, A., Qu, X., Garuti, R., Liang, X. H., Mizushima, N., Packer, M., Schneider, M. D. and Levine, B. (2005). Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 122, 927-939.
-
(2005)
Cell
, vol.122
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
Garuti, R.4
Liang, X.H.5
Mizushima, N.6
Packer, M.7
Schneider, M.D.8
Levine, B.9
-
44
-
-
79955377543
-
TRIM5 is an innate immune sensor for the retrovirus capsid lattice
-
Pertel, T., Hausmann, S., Morger, D., Zü ger, S., Guerra, J., Lascano, J., Reinhard, C., Santoni, F. A., Uchil, P. D., Chatel, L. et al. (2011). TRIM5 is an innate immune sensor for the retrovirus capsid lattice. Nature 472, 361-365.
-
(2011)
Nature
, vol.472
, pp. 361-365
-
-
Pertel, T.1
Hausmann, S.2
Morger, D.3
Züger, S.4
Guerra, J.5
Lascano, J.6
Reinhard, C.7
Santoni, F.A.8
Uchil, P.D.9
Chatel, L.10
-
45
-
-
84922689340
-
Degradation of AMPK by a cancer-specific ubiquitin ligase
-
Pineda, C. T., Ramanathan, S., Fon Tacer, K., Weon, J. L., Potts, M. B., Ou, Y.-H., White, M. A. and Potts, P. R. (2015). Degradation of AMPK by a cancer-specific ubiquitin ligase. Cell 160, 715-728.
-
(2015)
Cell
, vol.160
, pp. 715-728
-
-
Pineda, C.T.1
Ramanathan, S.2
Fon Tacer, K.3
Weon, J.L.4
Potts, M.B.5
Ou, Y.-H.6
White, M.A.7
Potts, P.R.8
-
46
-
-
58149344946
-
Midbody ring disposal by autophagy is a postabscission event of cytokinesis
-
Pohl, C. and Jentsch, S. (2009). Midbody ring disposal by autophagy is a postabscission event of cytokinesis. Nat. Cell Biol. 11, 65-70.
-
(2009)
Nat. Cell Biol
, vol.11
, pp. 65-70
-
-
Pohl, C.1
Jentsch, S.2
-
47
-
-
84941941753
-
Post-translationally-modified structures in the autophagy machinery: an integrative perspective
-
Popelka, H. and Klionsky, D. J. (2015). Post-translationally-modified structures in the autophagy machinery: an integrative perspective. FEBS J. 282, 3474-3488.
-
(2015)
FEBS J
, vol.282
, pp. 3474-3488
-
-
Popelka, H.1
Klionsky, D.J.2
-
48
-
-
84898624312
-
Self and nonself: how autophagy targets mitochondria and bacteria
-
Randow, F. and Youle, R. J. (2014). Self and nonself: how autophagy targets mitochondria and bacteria. Cell Host Microbe 15, 403-411.
-
(2014)
Cell Host Microbe
, vol.15
, pp. 403-411
-
-
Randow, F.1
Youle, R.J.2
-
49
-
-
17744371839
-
The tripartite motif family identifies cell compartments
-
Reymond, A., Meroni, G., Fantozzi, A., Merla, G., Cairo, S., Luzi, L., Riganelli, D., Zanaria, E., Messali, S., Cainarca, S. et al. (2001). The tripartite motif family identifies cell compartments. EMBO J. 20, 2140-2151.
-
(2001)
EMBO J
, vol.20
, pp. 2140-2151
-
-
Reymond, A.1
Meroni, G.2
Fantozzi, A.3
Merla, G.4
Cairo, S.5
Luzi, L.6
Riganelli, D.7
Zanaria, E.8
Messali, S.9
Cainarca, S.10
-
50
-
-
84892859905
-
Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy
-
Rogov, V., Dö tsch, V., Johansen, T. and Kirkin, V. (2014). Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy. Mol. Cell 53, 167-178.
-
(2014)
Mol. Cell
, vol.53
, pp. 167-178
-
-
Rogov, V.1
Dötsch, V.2
Johansen, T.3
Kirkin, V.4
-
51
-
-
84880331368
-
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
-
Russell, R. C., Tian, Y., Yuan, H., Park, H. W., Chang, Y.-Y., Kim, J., Kim, H., Neufeld, T. P., Dillin, A. and Guan, K.-L. (2013). ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase. Nat. Cell Biol. 15, 741-750.
-
(2013)
Nat. Cell Biol
, vol.15
, pp. 741-750
-
-
Russell, R.C.1
Tian, Y.2
Yuan, H.3
Park, H.W.4
Chang, Y.-Y.5
Kim, J.6
Kim, H.7
Neufeld, T.P.8
Dillin, A.9
Guan, K.-L.10
-
52
-
-
80955177196
-
TFEB links autophagy to lysosomal biogenesis
-
Settembre, C., Di Malta, C., Polito, V. A., Garcia Arencibia, M., Vetrini, F., Erdin, S., Erdin, S. U., Huynh, T., Medina, D., Colella, P. et al. (2011). TFEB links autophagy to lysosomal biogenesis. Science 332, 1429-1433.
-
(2011)
Science
, vol.332
, pp. 1429-1433
-
-
Settembre, C.1
Di Malta, C.2
Polito, V.A.3
Garcia Arencibia, M.4
Vetrini, F.5
Erdin, S.6
Erdin, S.U.7
Huynh, T.8
Medina, D.9
Colella, P.10
-
53
-
-
84857997408
-
A lysosome-tonucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
-
Settembre, C., Zoncu, R., Medina, D. L., Vetrini, F., Erdin, S., Huynh, T., Ferron, M., Karsenty, G., Vellard, M. C., Facchinetti, V. et al. (2012). A lysosome-tonucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. EMBO J. 31, 1095-1108.
-
(2012)
EMBO J
, vol.31
, pp. 1095-1108
-
-
Settembre, C.1
Zoncu, R.2
Medina, D.L.3
Vetrini, F.4
Erdin, S.5
Huynh, T.6
Ferron, M.7
Karsenty, G.8
Vellard, M.C.9
Facchinetti, V.10
-
54
-
-
77953858790
-
TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy
-
Shi, C. S. and Kehrl, J. H. (2010). TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy. Sci. Signal 3, ra42.
-
(2010)
Sci. Signal
, vol.3
-
-
Shi, C.S.1
Kehrl, J.H.2
-
55
-
-
84901815187
-
Cargo recognition and trafficking in selective autophagy
-
Stolz, A., Ernst, A. and Dikic, I. (2014). Cargo recognition and trafficking in selective autophagy. Nat. Cell Biol. 16, 495-501.
-
(2014)
Nat. Cell Biol
, vol.16
, pp. 495-501
-
-
Stolz, A.1
Ernst, A.2
Dikic, I.3
-
56
-
-
1542288934
-
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys
-
Stremlau, M., Owens, C. M., Perron, M. J., Kiessling, M., Autissier, P. and Sodroski, J. (2004). The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature 427, 848-853.
-
(2004)
Nature
, vol.427
, pp. 848-853
-
-
Stremlau, M.1
Owens, C.M.2
Perron, M.J.3
Kiessling, M.4
Autissier, P.5
Sodroski, J.6
-
57
-
-
84983718691
-
Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells
-
Tai, W.-T., Shiau, C.-W., Chen, H.-L., Liu, C.-Y., Lin, C.-S., Cheng, A.-L., Chen, P.-J. and Chen, K.-F. (2013). Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells. Cell Death Dis. 4, e485.
-
(2013)
Cell Death Dis
, vol.4
-
-
Tai, W.-T.1
Shiau, C.-W.2
Chen, H.-L.3
Liu, C.-Y.4
Lin, C.-S.5
Cheng, A.-L.6
Chen, P.-J.7
Chen, K.-F.8
-
58
-
-
84863012159
-
TGFbeta-activated kinase 1 (TAK1)-binding proteins (TAB) 2 and 3 negatively regulate autophagy
-
Takaesu, G., Kobayashi, T. and Yoshimura, A. (2012). TGFbeta-activated kinase 1 (TAK1)-binding proteins (TAB) 2 and 3 negatively regulate autophagy. J. Biochem. 151, 157-166.
-
(2012)
J. Biochem
, vol.151
, pp. 157-166
-
-
Takaesu, G.1
Kobayashi, T.2
Yoshimura, A.3
-
59
-
-
84885638436
-
Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites
-
Tang, Z., Lin, M. G., Stowe, T. R., Chen, S., Zhu, M., Stearns, T., Franco, B. and Zhong, Q. (2013). Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites. Nature 502, 254-257.
-
(2013)
Nature
, vol.502
, pp. 254-257
-
-
Tang, Z.1
Lin, M.G.2
Stowe, T.R.3
Chen, S.4
Zhu, M.5
Stearns, T.6
Franco, B.7
Zhong, Q.8
-
60
-
-
65049090139
-
TRIM44 interacts with and stabilizes terf, a TRIM ubiquitin E3 ligase
-
Urano, T., Usui, T., Takeda, S., Ikeda, K., Okada, A., Ishida, Y., Iwayanagi, T., Otomo, J., Ouchi, Y. and Inoue, S. (2009). TRIM44 interacts with and stabilizes terf, a TRIM ubiquitin E3 ligase. Biochem. Biophys. Res. Commun. 383, 263-268.
-
(2009)
Biochem. Biophys. Res. Commun
, vol.383
, pp. 263-268
-
-
Urano, T.1
Usui, T.2
Takeda, S.3
Ikeda, K.4
Okada, A.5
Ishida, Y.6
Iwayanagi, T.7
Otomo, J.8
Ouchi, Y.9
Inoue, S.10
-
61
-
-
44949237240
-
JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
-
Wei, Y., Pattingre, S., Sinha, S., Bassik, M. and Levine, B. (2008). JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol. Cell 30, 678-688.
-
(2008)
Mol. Cell
, vol.30
, pp. 678-688
-
-
Wei, Y.1
Pattingre, S.2
Sinha, S.3
Bassik, M.4
Levine, B.5
-
62
-
-
85003048223
-
The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation
-
Wei, Y., An, Z., Zou, Z., Sumpter, R., Su, M., Zang, X., Sinha, S., Gaestel, M. and Levine, B. (2015). The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation. Elife 4, e05289.
-
(2015)
Elife
, vol.4
-
-
Wei, Y.1
An, Z.2
Zou, Z.3
Sumpter, R.4
Su, M.5
Zang, X.6
Sinha, S.7
Gaestel, M.8
Levine, B.9
-
63
-
-
84876865718
-
Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy
-
Yang, Y., Fiskus, W., Yong, B., Atadja, P., Takahashi, Y., Pandita, T. K., Wang, H.-G. and Bhalla, K. N. (2013). Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy. Proc. Natl. Acad. Sci. USA 110, 6841-6846.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 6841-6846
-
-
Yang, Y.1
Fiskus, W.2
Yong, B.3
Atadja, P.4
Takahashi, Y.5
Pandita, T.K.6
Wang, H.-G.7
Bhalla, K.N.8
-
64
-
-
64049113909
-
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
-
Zhong, Y., Wang, Q. J., Li, X., Yan, Y., Backer, J. M., Chait, B. T., Heintz, N. and Yue, Z. (2009). Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat. Cell Biol. 11, 468-476.
-
(2009)
Nat. Cell Biol
, vol.11
, pp. 468-476
-
-
Zhong, Y.1
Wang, Q.J.2
Li, X.3
Yan, Y.4
Backer, J.M.5
Chait, B.T.6
Heintz, N.7
Yue, Z.8
|