-
1
-
-
84867773087
-
Mitophagy: mechanisms, pathophysiological roles, and analysis
-
Ding WX, Yin XM. Mitophagy: mechanisms, pathophysiological roles, and analysis. Biol Chem. 2012; 393: 547-64.
-
(2012)
Biol Chem
, vol.393
, pp. 547-564
-
-
Ding, W.X.1
Yin, X.M.2
-
3
-
-
84863430453
-
Mitophagy: a complex mechanism of mitochondrial removal
-
Novak I. Mitophagy: a complex mechanism of mitochondrial removal. Antioxid Redox Signal. 2012; 17: 794-802.
-
(2012)
Antioxid Redox Signal
, vol.17
, pp. 794-802
-
-
Novak, I.1
-
5
-
-
84871005673
-
The pathways of mitophagy for quality control and clearance of mitochondria
-
Ashrafi G, Schwarz TL. The pathways of mitophagy for quality control and clearance of mitochondria. Cell Death Differ. 2013; 20: 31-42.
-
(2013)
Cell Death Differ
, vol.20
, pp. 31-42
-
-
Ashrafi, G.1
Schwarz, T.L.2
-
6
-
-
84879606527
-
Molecular signaling toward mitophagy and its physiological significance
-
Feng D, Liu L, Zhu Y, Chen Q. Molecular signaling toward mitophagy and its physiological significance. Exp Cell Res. 2013; 319: 1697-1705.
-
(2013)
Exp Cell Res
, vol.319
, pp. 1697-1705
-
-
Feng, D.1
Liu, L.2
Zhu, Y.3
Chen, Q.4
-
7
-
-
84871749760
-
Mitochondrial morphology in mitophagy and macroautophagy
-
Gomes LC, Scorrano L. Mitochondrial morphology in mitophagy and macroautophagy. Biochim Biophys Acta. 2013; 1833: 205-12.
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 205-212
-
-
Gomes, L.C.1
Scorrano, L.2
-
8
-
-
84910141948
-
Mitochondrial dynamics and inheritance during cell division, development and disease
-
Mishra P, Chan DC. Mitochondrial dynamics and inheritance during cell division, development and disease. Nat Rev Mol Cell Biol. 2014; 15: 634-46.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 634-646
-
-
Mishra, P.1
Chan, D.C.2
-
9
-
-
84940722108
-
Selective removal of mitochondria via mitophagy: distinct pathways for different mitochondrial stresses
-
Wei H, Liu L, Chen Q. Selective removal of mitochondria via mitophagy: distinct pathways for different mitochondrial stresses. Biochim Biophys Acta. 2015; 1853: 2784-90.
-
(2015)
Biochim Biophys Acta
, vol.1853
, pp. 2784-2790
-
-
Wei, H.1
Liu, L.2
Chen, Q.3
-
10
-
-
84897048042
-
Mitochondrial quality control in neurodegenerative diseases
-
Dupuis L. Mitochondrial quality control in neurodegenerative diseases. Biochimie. 2014; 100: 177-83.
-
(2014)
Biochimie
, vol.100
, pp. 177-183
-
-
Dupuis, L.1
-
12
-
-
84885653993
-
Defective quality control mechanisms and accumulation of damaged mitochondria link Gaucher and Parkinson diseases
-
Osellame LD, Duchen MR. Defective quality control mechanisms and accumulation of damaged mitochondria link Gaucher and Parkinson diseases. Autophagy. 2013; 9: 1633-35.
-
(2013)
Autophagy
, vol.9
, pp. 1633-1635
-
-
Osellame, L.D.1
Duchen, M.R.2
-
13
-
-
84897454469
-
Quality control gone wrong: mitochondria, lysosomal storage disorders and neurodegeneration
-
Osellame LD, Duchen MR. Quality control gone wrong: mitochondria, lysosomal storage disorders and neurodegeneration. Br J Pharmacol. 2014; 171: 1958-1972.
-
(2014)
Br J Pharmacol
, vol.171
, pp. 1958-1972
-
-
Osellame, L.D.1
Duchen, M.R.2
-
14
-
-
84921369563
-
The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease
-
Pickrell AM, Youle RJ. The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease. Neuron. 2015; 85: 257-73.
-
(2015)
Neuron
, vol.85
, pp. 257-273
-
-
Pickrell, A.M.1
Youle, R.J.2
-
15
-
-
84925298301
-
Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease
-
Ryan BJ, Hoek S, Fon EA, Wade-Martins R. Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease. Trends Biochem Sci. 2015; 40: 200-10.
-
(2015)
Trends Biochem Sci
, vol.40
, pp. 200-210
-
-
Ryan, B.J.1
Hoek, S.2
Fon, E.A.3
Wade-Martins, R.4
-
16
-
-
84887387419
-
After the banquet: mitochondrial biogenesis, mitophagy, and cell survival
-
Zhu J, Wang KZ, Chu CT. After the banquet: mitochondrial biogenesis, mitophagy, and cell survival. Autophagy. 2013; 9: 1663-76.
-
(2013)
Autophagy
, vol.9
, pp. 1663-1676
-
-
Zhu, J.1
Wang, K.Z.2
Chu, C.T.3
-
17
-
-
84880893068
-
Autophagy in stem cells
-
Guan JL, Simon AK, Prescott M, Menendez JA, Liu F, Wang F, Wang C, Wolvetang E, Vazquez-Martin A, Zhang J. Autophagy in stem cells. Autophagy. 2013; 9: 830-49.
-
(2013)
Autophagy
, vol.9
, pp. 830-849
-
-
Guan, J.L.1
Simon, A.K.2
Prescott, M.3
Menendez, J.A.4
Liu, F.5
Wang, F.6
Wang, C.7
Wolvetang, E.8
Vazquez-Martin, A.9
Zhang, J.10
-
18
-
-
84887456727
-
Mitophagy in hematopoietic stem cells: the case for exploration
-
Joshi A, Kundu M. Mitophagy in hematopoietic stem cells: the case for exploration. Autophagy. 2013; 9: 1737-49.
-
(2013)
Autophagy
, vol.9
, pp. 1737-1749
-
-
Joshi, A.1
Kundu, M.2
-
19
-
-
84934434639
-
Energy metabolism and metabolic sensors in stem cells: the metabostem crossroads of aging and cancer
-
Menendez JA, Joven J. Energy metabolism and metabolic sensors in stem cells: the metabostem crossroads of aging and cancer. Adv Exp Med Biol. 2014; 824: 117-40.
-
(2014)
Adv Exp Med Biol
, vol.824
, pp. 117-140
-
-
Menendez, J.A.1
Joven, J.2
-
20
-
-
80655140600
-
mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to stem cell renewal and aging
-
Menendez JA, Vellon L, Oliveras-Ferraros C, Cufí S, Vazquez-Martin A. mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to stem cell renewal and aging. Cell Cycle. 2011; 10: 3658-77.
-
(2011)
Cell Cycle
, vol.10
, pp. 3658-3677
-
-
Menendez, J.A.1
Vellon, L.2
Oliveras-Ferraros, C.3
Cufí, S.4
Vazquez-Martin, A.5
-
21
-
-
83555169408
-
Crosstalk between mitochondrial (dys)function and mitochondrial abundance
-
Michel S, Wanet A, De Pauw A, Rommelaere G, Arnould T, Renard, P. Crosstalk between mitochondrial (dys)function and mitochondrial abundance. J Cell Physiol. 2012; 227: 2297-10.
-
(2012)
J Cell Physiol
, vol.227
, pp. 2297-2310
-
-
Michel, S.1
Wanet, A.2
De Pauw, A.3
Rommelaere, G.4
Arnould, T.5
Renard, P.6
-
22
-
-
84874698634
-
Autophagic control of cell 'stemness'
-
Pan H, Cai N, Li M, Liu GH, Izpisua Belmonte JC. Autophagic control of cell 'stemness'. EMBO Mol Med. 2013; 5: 327-31.
-
(2013)
EMBO Mol Med
, vol.5
, pp. 327-331
-
-
Pan, H.1
Cai, N.2
Li, M.3
Liu, G.H.4
Izpisua Belmonte, J.C.5
-
23
-
-
84872340936
-
Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and aging
-
Phadwal K, Watson AS, Simon AK. Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and aging. Cell Mol Life Sci. 2013; 70: 89-103.
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 89-103
-
-
Phadwal, K.1
Watson, A.S.2
Simon, A.K.3
-
24
-
-
84857489373
-
Autophagy in stem cell maintenance and differentiation
-
Vessoni AT, Muotri AR, Okamoto OK. Autophagy in stem cell maintenance and differentiation. Stem Cells Dev. 2012; 21: 513-20.
-
(2012)
Stem Cells Dev
, vol.21
, pp. 513-520
-
-
Vessoni, A.T.1
Muotri, A.R.2
Okamoto, O.K.3
-
25
-
-
84859424813
-
Mitochondrial bioenergetic function and metabolic plasticity in stem cell differentiation and cellular reprogramming
-
Chen CT, Hsu SH, Wei YH. Mitochondrial bioenergetic function and metabolic plasticity in stem cell differentiation and cellular reprogramming. Biochim Biophys Acta. 2012; 1820: 571-76.
-
(2012)
Biochim Biophys Acta
, vol.1820
, pp. 571-576
-
-
Chen, C.T.1
Hsu, S.H.2
Wei, Y.H.3
-
26
-
-
79960945131
-
Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming
-
Folmes CD, Nelson TJ, Martinez-Fernandez A, Arrell DK, Lindor JZ, Dzeja PP, Ikeda Y, Perez-Terzic C, Terzic, A. Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming. Cell Metab. 2011; 14: 264-71.
-
(2011)
Cell Metab
, vol.14
, pp. 264-271
-
-
Folmes, C.D.1
Nelson, T.J.2
Martinez-Fernandez, A.3
Arrell, D.K.4
Lindor, J.Z.5
Dzeja, P.P.6
Ikeda, Y.7
Perez-Terzic, C.8
Terzic, A.9
-
27
-
-
82755195582
-
Energy metabolism in nuclear reprogramming
-
Folmes CD, Nelson TJ, Terzic A. Energy metabolism in nuclear reprogramming. Biomark Med. 2011; 5: 715-29.
-
(2011)
Biomark Med
, vol.5
, pp. 715-729
-
-
Folmes, C.D.1
Nelson, T.J.2
Terzic, A.3
-
28
-
-
84868347607
-
Metabolic plasticity in stem cell homeostasis and differentiation
-
Folmes CD, Dzeja PP, Nelson TJ, Terzic, A. Metabolic plasticity in stem cell homeostasis and differentiation. Cell Stem Cell. 2012; 11: 596-06.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 596-606
-
-
Folmes, C.D.1
Dzeja, P.P.2
Nelson, T.J.3
Terzic, A.4
-
30
-
-
84881498096
-
Metabolome and metaboproteome remodeling in nuclear reprogramming
-
Folmes CD, Arrell DK, Zlatkovic-Lindor J, Martinez-Fernandez A, Perez-Terzic C, Nelson TJ, Terzic A. Metabolome and metaboproteome remodeling in nuclear reprogramming. Cell Cycle. 2013; 12: 2355-65.
-
(2013)
Cell Cycle
, vol.12
, pp. 2355-2365
-
-
Folmes, C.D.1
Arrell, D.K.2
Zlatkovic-Lindor, J.3
Martinez-Fernandez, A.4
Perez-Terzic, C.5
Nelson, T.J.6
Terzic, A.7
-
31
-
-
84872613340
-
Nuclear reprogramming with c-Myc potentiates glycolytic capacity of derived induced pluripotent stem cells
-
Folmes CD, Martinez-Fernandez A, Faustino RS, Yamada S, Perez-Terzic C, Nelson TJ, Terzic A. Nuclear reprogramming with c-Myc potentiates glycolytic capacity of derived induced pluripotent stem cells. J Cardiovasc Transl Res. 2013; 6: 10-21.
-
(2013)
J Cardiovasc Transl Res
, vol.6
, pp. 10-21
-
-
Folmes, C.D.1
Martinez-Fernandez, A.2
Faustino, R.S.3
Yamada, S.4
Perez-Terzic, C.5
Nelson, T.J.6
Terzic, A.7
-
32
-
-
84896929687
-
Metabolic requirements for the maintenance of self-renewing stem cells
-
Ito K, Suda T. Metabolic requirements for the maintenance of self-renewing stem cells. Nat Rev Mol Cell Biol. 2014; 15: 243-56.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 243-256
-
-
Ito, K.1
Suda, T.2
-
33
-
-
84855490988
-
The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming
-
Panopoulos AD, Yanes O, Ruiz S, Kida YS, Diep D, Tautenhahn R, Herrerías A, Batchelder EM, Plongthongkum N, Lutz M, Berggren WT, Zhang K, Evans RM, Siuzdak G, Izpisua Belmonte JC. The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming. Cell Res. 2012; 22: 168-177.
-
(2012)
Cell Res
, vol.22
, pp. 168-177
-
-
Panopoulos, A.D.1
Yanes, O.2
Ruiz, S.3
Kida, Y.S.4
Diep, D.5
Tautenhahn, R.6
Herrerías, A.7
Batchelder, E.M.8
Plongthongkum, N.9
Lutz, M.10
Berggren, W.T.11
Zhang, K.12
Evans, R.M.13
Siuzdak, G.14
Izpisua Belmonte, J.C.15
-
34
-
-
84883620045
-
Interference with the mitochondrial bioenergetics fuels reprogramming to pluripotency via facilitation of the glycolytic transition
-
Son MJ, Jeong BR, Kwon Y, Cho YS. Interference with the mitochondrial bioenergetics fuels reprogramming to pluripotency via facilitation of the glycolytic transition. Int J Biochem Cell Biol. 2013; 45: 2512-18.
-
(2013)
Int J Biochem Cell Biol
, vol.45
, pp. 2512-2518
-
-
Son, M.J.1
Jeong, B.R.2
Kwon, Y.3
Cho, Y.S.4
-
35
-
-
84921260212
-
Pluripotent stem cell energy metabolism: an update
-
Teslaa T, Teitell MA. Pluripotent stem cell energy metabolism: an update. EMBO J. 2015; 34: 138-53.
-
(2015)
EMBO J
, vol.34
, pp. 138-153
-
-
Teslaa, T.1
Teitell, M.A.2
-
36
-
-
84896306292
-
Mitochondrial function in pluripotent stem cells and cellular reprogramming
-
Bukowiecki R, Adjaye J, Prigione, A. Mitochondrial function in pluripotent stem cells and cellular reprogramming. Gerontology. 2014; 60: 174-82.
-
(2014)
Gerontology
, vol.60
, pp. 174-182
-
-
Bukowiecki, R.1
Adjaye, J.2
Prigione, A.3
-
37
-
-
79960012954
-
Modulation of mitochondrial biogenesis and bioenergetic metabolism upon in vitro and in vivo differentiation of human ES and iPS cells
-
Prigione A, Adjaye J. Modulation of mitochondrial biogenesis and bioenergetic metabolism upon in vitro and in vivo differentiation of human ES and iPS cells. Int J Dev Bio. 2010; 54: 1729-41.
-
(2010)
Int J Dev Bio
, vol.54
, pp. 1729-1741
-
-
Prigione, A.1
Adjaye, J.2
-
38
-
-
84988239965
-
A mitochondrial strategy for safeguarding the reprogrammed genome
-
Prigione A, Adjaye J. A mitochondrial strategy for safeguarding the reprogrammed genome. Cell Regen (Lond). 2014; 3: 5.
-
(2014)
Cell Regen (Lond)
, vol.3
, pp. 5
-
-
Prigione, A.1
Adjaye, J.2
-
39
-
-
77951002352
-
The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells
-
Prigione A, Fauler B, Lurz R, Lehrach H, Adjaye J. The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells. Stem Cells. 2010; 28: 721-33.
-
(2010)
Stem Cells
, vol.28
, pp. 721-733
-
-
Prigione, A.1
Fauler, B.2
Lurz, R.3
Lehrach, H.4
Adjaye, J.5
-
40
-
-
81055124788
-
Mitochondrial-associated cell death mechanisms are reset to an embryonic-like state in aged donor-derived iPS cells harboring chromosomal aberrations
-
Prigione A, Hossini AM, Lichtner B, Serin A, Fauler B, Megges M, Lurz R, Lehrach H, Makrantonaki E, Zouboulis CC, Adjaye J. Mitochondrial-associated cell death mechanisms are reset to an embryonic-like state in aged donor-derived iPS cells harboring chromosomal aberrations. PLoS One. 2011; 6: e27352.
-
(2011)
PLoS One
, vol.6
-
-
Prigione, A.1
Hossini, A.M.2
Lichtner, B.3
Serin, A.4
Fauler, B.5
Megges, M.6
Lurz, R.7
Lehrach, H.8
Makrantonaki, E.9
Zouboulis, C.C.10
Adjaye, J.11
-
42
-
-
79952209101
-
Mitochondrial rejuvenation after induced pluripotency
-
Suhr ST, Chang EA, Tjong J, Alcasid N, Perkins GA, Goissis MD, Ellisman MH, Perez GI, Cibelli JB. Mitochondrial rejuvenation after induced pluripotency. PLoS One. 2010; 5: e14095.
-
(2010)
PLoS One
, vol.5
-
-
Suhr, S.T.1
Chang, E.A.2
Tjong, J.3
Alcasid, N.4
Perkins, G.A.5
Goissis, M.D.6
Ellisman, M.H.7
Perez, G.I.8
Cibelli, J.B.9
-
43
-
-
84873624215
-
The mitochondrial H(+)-ATP synthase and the lipogenic switch: new core components of metabolic reprogramming in induced pluripotent stem (iPS) cells
-
Vazquez-Martin A, Corominas-Faja B, Cufi S, Vellon L, Oliveras-Ferraros C, Menendez OJ, Joven J, Lupu R, Menendez JA. The mitochondrial H(+)-ATP synthase and the lipogenic switch: new core components of metabolic reprogramming in induced pluripotent stem (iPS) cells. Cell Cycle. 2013; 12: 207-18.
-
(2013)
Cell Cycle
, vol.12
, pp. 207-218
-
-
Vazquez-Martin, A.1
Corominas-Faja, B.2
Cufi, S.3
Vellon, L.4
Oliveras-Ferraros, C.5
Menendez, O.J.6
Joven, J.7
Lupu, R.8
Menendez, J.A.9
-
44
-
-
77953916259
-
A transcriptional roadmap to the induction of pluripotency in somatic cells
-
Wang Y, Mah N, Prigione A, Wolfrum K, Andrade-Navarro MA, Adjaye J. A transcriptional roadmap to the induction of pluripotency in somatic cells. Stem Cell Rev. 2010; 6: 282-96.
-
(2010)
Stem Cell Rev
, vol.6
, pp. 282-296
-
-
Wang, Y.1
Mah, N.2
Prigione, A.3
Wolfrum, K.4
Andrade-Navarro, M.A.5
Adjaye, J.6
-
45
-
-
84883489939
-
Mitochondrial regulation in pluripotent stem cells
-
Xu X, Duan S, Yi F, Ocampo A, Liu GH, Izpisua Belmonte JC. Mitochondrial regulation in pluripotent stem cells. Cell Metab. 2013; 18: 325-32.
-
(2013)
Cell Metab
, vol.18
, pp. 325-332
-
-
Xu, X.1
Duan, S.2
Yi, F.3
Ocampo, A.4
Liu, G.H.5
Izpisua Belmonte, J.C.6
-
46
-
-
84929292023
-
ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency
-
Kida YS, Kawamura T, Wei Z, Sogo T, Jacinto S, Shigeno A, Kushige H, Yoshihara E, Liddle C, Ecker JR, Yu RT, Atkins AR, Downes M, Evans RM. ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency. Cell Stem Cell. 2015; 16: 547-55.
-
(2015)
Cell Stem Cell
, vol.16
, pp. 547-555
-
-
Kida, Y.S.1
Kawamura, T.2
Wei, Z.3
Sogo, T.4
Jacinto, S.5
Shigeno, A.6
Kushige, H.7
Yoshihara, E.8
Liddle, C.9
Ecker, J.R.10
Yu, R.T.11
Atkins, A.R.12
Downes, M.13
Evans, R.M.14
-
47
-
-
84901349234
-
Transient activation of autophagy via Sox2-mediated suppression of mTOR is an important early step in reprogramming to pluripotency
-
Wang S, Xia P, Ye B, Huang G, Liu J, Fan Z. Transient activation of autophagy via Sox2-mediated suppression of mTOR is an important early step in reprogramming to pluripotency. Cell Stem Cell. 2013; 13: 617-25.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 617-625
-
-
Wang, S.1
Xia, P.2
Ye, B.3
Huang, G.4
Liu, J.5
Fan, Z.6
-
48
-
-
84887987260
-
Unveiling the critical role of REX1 in the regulation of human stem cell pluripotency
-
Son MY, Choi H, Han YM, Cho YS. Unveiling the critical role of REX1 in the regulation of human stem cell pluripotency. Stem Cells. 2013; 31: 2374-87.
-
(2013)
Stem Cells
, vol.31
, pp. 2374-2387
-
-
Son, M.Y.1
Choi, H.2
Han, Y.M.3
Cho, Y.S.4
-
49
-
-
84947488862
-
Mitofusins deficiency elicits mitochondrial metabolic reprogramming to pluripotency
-
Son MJ, Kwon Y, Son MY, Seol B, Choi HS, Ryu SW, Choi C, Cho YS. Mitofusins deficiency elicits mitochondrial metabolic reprogramming to pluripotency. Cell Death Differ. 2015; 22: 1957-69.
-
(2015)
Cell Death Differ
, vol.22
, pp. 1957-1969
-
-
Son, M.J.1
Kwon, Y.2
Son, M.Y.3
Seol, B.4
Choi, H.S.5
Ryu, S.W.6
Choi, C.7
Cho, Y.S.8
-
50
-
-
84865031202
-
Mitochondrial fusion by pharmacological manipulation impedes somatic cell reprogramming to pluripotency: new insight into the role of mitophagy in cell stemness
-
Vazquez-Martin A, Cufi S, Corominas-Faja B, Oliveras-Ferraros C, Vellon L, Menendez JA. Mitochondrial fusion by pharmacological manipulation impedes somatic cell reprogramming to pluripotency: new insight into the role of mitophagy in cell stemness. Aging (Albany NY). 2012; 4: 393-401. doi: 10.18632/aging.100465.
-
(2012)
Aging (Albany NY)
, vol.4
, pp. 393-401
-
-
Vazquez-Martin, A.1
Cufi, S.2
Corominas-Faja, B.3
Oliveras-Ferraros, C.4
Vellon, L.5
Menendez, J.A.6
-
51
-
-
84913543630
-
Drp1 is dispensable for mitochondria biogenesis in induction to pluripotency but required for differentiation of embryonic stem cells
-
Wang L, Ye X, Zhao Q, Zhou Z, Dan J, Zhu Y, Chen Q, Liu L. Drp1 is dispensable for mitochondria biogenesis in induction to pluripotency but required for differentiation of embryonic stem cells. Stem Cells Dev. 2014; 23: 2422-34.
-
(2014)
Stem Cells Dev
, vol.23
, pp. 2422-2434
-
-
Wang, L.1
Ye, X.2
Zhao, Q.3
Zhou, Z.4
Dan, J.5
Zhu, Y.6
Chen, Q.7
Liu, L.8
-
52
-
-
79953156438
-
Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance
-
Heeman B, Van den Haute C, Aelvoet SA, Valsecchi F, Rodenburg RJ, Reumers V, Debyser Z, Callewaert G, Koopman WJ, Willems PH, Baekelandt V. Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance. J Cell Sci. 2011; 124: 1115-25.
-
(2011)
J Cell Sci
, vol.124
, pp. 1115-1125
-
-
Heeman, B.1
Van den Haute, C.2
Aelvoet, S.A.3
Valsecchi, F.4
Rodenburg, R.J.5
Reumers, V.6
Debyser, Z.7
Callewaert, G.8
Koopman, W.J.9
Willems, P.H.10
Baekelandt, V.11
-
53
-
-
84858207443
-
Loss-of-function rodent models for parkin and PINK1
-
Oliveras-Salvá M, Van Rompuy AS, Heeman B, Van den Haute C, Baekelandt V. Loss-of-function rodent models for parkin and PINK1. J Parkinsons Dis. 2011; 1: 229-51.
-
(2011)
J Parkinsons Dis
, vol.1
, pp. 229-251
-
-
Oliveras-Salvá, M.1
Van Rompuy, A.S.2
Heeman, B.3
Van den Haute, C.4
Baekelandt, V.5
-
54
-
-
77953877676
-
A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease
-
Chu CT. A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease. Hum Mol Genet. 2010; 19: R28-R37.
-
(2010)
Hum Mol Genet
, vol.19
, pp. R28-R37
-
-
Chu, C.T.1
-
55
-
-
33745589773
-
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
-
Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, Seol JH, Yoo SJ, Hay BA, Guo M. Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature. 2006; 441: 1162-66.
-
(2006)
Nature
, vol.441
, pp. 1162-1166
-
-
Clark, I.E.1
Dodson, M.W.2
Jiang, C.3
Cao, J.H.4
Huh, J.R.5
Seol, J.H.6
Yoo, S.J.7
Hay, B.A.8
Guo, M.9
-
56
-
-
55749090654
-
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
-
Deng H, Dodson MW, Huang H, Guo M. The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila. Proc Natl Acad Sci U S A. 2008; 105: 14503-508.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 14503-14508
-
-
Deng, H.1
Dodson, M.W.2
Huang, H.3
Guo, M.4
-
57
-
-
84922776083
-
PINK1/Parkin-mediated mitophagy in mammalian cells
-
Eiyama A, Okamoto K. PINK1/Parkin-mediated mitophagy in mammalian cells. Curr Opin Cell Biol. 2015; 33: 95-101.
-
(2015)
Curr Opin Cell Biol
, vol.33
, pp. 95-101
-
-
Eiyama, A.1
Okamoto, K.2
-
58
-
-
49649097747
-
Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
-
Gautier CA, Kitada T, Shen J. Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress. Proc Natl Acad Sci U S A. 2008; 105: 11364-369.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 11364-11369
-
-
Gautier, C.A.1
Kitada, T.2
Shen, J.3
-
59
-
-
78649463381
-
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
-
Gegg ME, Cooper JM, Chau KY, Rojo M, Schapira AH, Taanman JW. Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy. Hum Mol Genet. 2010; 19: 4861-70.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4861-4870
-
-
Gegg, M.E.1
Cooper, J.M.2
Chau, K.Y.3
Rojo, M.4
Schapira, A.H.5
Taanman, J.W.6
-
60
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
Geisler S, Holmström KM, Skujat D, Fiesel FC, Rothfuss OC, Kahle PJ, Springer W. PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat Cell Biol. 2010; 12: 119-31.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmström, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
Springer, W.7
-
61
-
-
77950371695
-
PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy
-
Kawajiri S, Saiki S, Sato S, Sato F, Hatano T, Eguchi H, Hattori N. PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy. FEBS Lett. 2010; 584: 1073-79.
-
(2010)
FEBS Lett
, vol.584
, pp. 1073-1079
-
-
Kawajiri, S.1
Saiki, S.2
Sato, S.3
Sato, F.4
Hatano, T.5
Eguchi, H.6
Hattori, N.7
-
62
-
-
79952324644
-
Regulation of PINK1-Parkin-mediated mitophagy
-
Springer W, Kahle PJ. Regulation of PINK1-Parkin-mediated mitophagy. Autophagy. 2011; 7: 266-78.
-
(2011)
Autophagy
, vol.7
, pp. 266-278
-
-
Springer, W.1
Kahle, P.J.2
-
63
-
-
75949098487
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
-
Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RL, Kim J, May J, Tocilescu MA, Liu W, Ko HS, Magrané J, Moore DJ, Dawson VL, et al. PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proc Natl Acad Sci U S A. 2010; 107: 378-83.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
Huang, Y.3
Cui, M.4
de Vries, R.L.5
Kim, J.6
May, J.7
Tocilescu, M.A.8
Liu, W.9
Ko, H.S.10
Magrané, J.11
Moore, D.J.12
Dawson, V.L.13
-
64
-
-
84871735126
-
Metformin limits the tumourigenicity of iPS cells without affecting their pluripotency
-
Vazquez-Martin A, Cufi S, Lopez-Bonet E, Corominas-Faja B, Oliveras-Ferraros C, Martin-Castillo B, Menendez JA. Metformin limits the tumourigenicity of iPS cells without affecting their pluripotency. Sci Rep. 2012; 2: 964.
-
(2012)
Sci Rep
, vol.2
, pp. 964
-
-
Vazquez-Martin, A.1
Cufi, S.2
Lopez-Bonet, E.3
Corominas-Faja, B.4
Oliveras-Ferraros, C.5
Martin-Castillo, B.6
Menendez, J.A.7
-
65
-
-
84857927867
-
Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells
-
Vazquez-Martin A, Vellon L, Quirós PM, Cufí S, Ruiz de Galarreta E, Oliveras-Ferraros C, Martin AG, Martin-Castillo B, López-Otín C, Menendez JA. Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells. Cell Cycle. 2012; 11: 974-89.
-
(2012)
Cell Cycle
, vol.11
, pp. 974-989
-
-
Vazquez-Martin, A.1
Vellon, L.2
Quirós, P.M.3
Cufí, S.4
Ruiz de Galarreta, E.5
Oliveras-Ferraros, C.6
Martin, A.G.7
Martin-Castillo, B.8
López-Otín, C.9
Menendez, J.A.10
-
66
-
-
78149408058
-
Empowering self-renewal and differentiation: the role of mitochondria in stem cells
-
Rehman J. Empowering self-renewal and differentiation: the role of mitochondria in stem cells. J Mol Med (Berl). 2010; 88: 981-86.
-
(2010)
J Mol Med (Berl)
, vol.88
, pp. 981-986
-
-
Rehman, J.1
-
67
-
-
33644606491
-
Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes
-
Rodriguez-Enriquez S, Kim I, Currin RT, Lemasters JJ. Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes. Autophagy. 2006; 2: 39-46.
-
(2006)
Autophagy
, vol.2
, pp. 39-46
-
-
Rodriguez-Enriquez, S.1
Kim, I.2
Currin, R.T.3
Lemasters, J.J.4
-
68
-
-
40249093059
-
A core Klf circuitry regulates self-renewal of embryonic stem cells
-
Jiang J, Chan YS, Loh YH, Cai J, Tong GQ, Lim CA, Robson P, Zhong S, Ng HH. A core Klf circuitry regulates self-renewal of embryonic stem cells. Nat Cell Biol. 2008; 10: 353-60.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 353-360
-
-
Jiang, J.1
Chan, Y.S.2
Loh, Y.H.3
Cai, J.4
Tong, G.Q.5
Lim, C.A.6
Robson, P.7
Zhong, S.8
Ng, H.H.9
-
69
-
-
0036285034
-
c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability
-
Vafa O, Wade M, Kern S, Beeche M, Pandita TK, Hampton GM, Wahl GM. c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability. Mol Cell. 2002; 9: 1031-44.
-
(2002)
Mol Cell
, vol.9
, pp. 1031-1044
-
-
Vafa, O.1
Wade, M.2
Kern, S.3
Beeche, M.4
Pandita, T.K.5
Hampton, G.M.6
Wahl, G.M.7
-
70
-
-
34248223064
-
The ever expanding role for c-Myc in promoting genomic instability
-
Prochownik EV, Li Y. The ever expanding role for c-Myc in promoting genomic instability. Cell Cycle. 2007; 6: 1024-29.
-
(2007)
Cell Cycle
, vol.6
, pp. 1024-1029
-
-
Prochownik, E.V.1
Li, Y.2
-
71
-
-
84943451038
-
MYC/PGC-1a Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells
-
Sancho P, Burgos-Ramos E, Tavera A, Bou Kheir T, Jagust P, Schoenhals M, Barneda D, Sellers K, Campos-Olivas R, Graña O, Viera CR, Yuneva M, Sainz B Jr, Heeschen C. MYC/PGC-1a Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells. Cell Metab. 2015; 22: 590-605.
-
(2015)
Cell Metab
, vol.22
, pp. 590-605
-
-
Sancho, P.1
Burgos-Ramos, E.2
Tavera, A.3
Bou Kheir, T.4
Jagust, P.5
Schoenhals, M.6
Barneda, D.7
Sellers, K.8
Campos-Olivas, R.9
Graña, O.10
Viera, C.R.11
Yuneva, M.12
Sainz, B.13
Heeschen, C.14
-
72
-
-
77957264475
-
Vitamin C promotes widespread yet specific DNA demethylation of the epigenome in human embryonic stem cells
-
Chung TL, Brena RM, Kolle G, Grimmond SM, Berman BP, Laird PW, Pera MF, Wolvetang EJ. Vitamin C promotes widespread yet specific DNA demethylation of the epigenome in human embryonic stem cells. Stem Cells. 2010; 28: 1848-55.
-
(2010)
Stem Cells
, vol.28
, pp. 1848-1855
-
-
Chung, T.L.1
Brena, R.M.2
Kolle, G.3
Grimmond, S.M.4
Berman, B.P.5
Laird, P.W.6
Pera, M.F.7
Wolvetang, E.J.8
-
73
-
-
73049112178
-
Vitamin C enhances the generation of mouse and human induced pluripotent stem cells
-
Esteban MA, Wang T, Qin B, Yang J, Qin D, Cai J, Li W, Weng Z, Chen J, Ni S, Chen K, Li Y, Liu X, Xu J, et al. Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell. 2010; 6: 71-79.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 71-79
-
-
Esteban, M.A.1
Wang, T.2
Qin, B.3
Yang, J.4
Qin, D.5
Cai, J.6
Li, W.7
Weng, Z.8
Chen, J.9
Ni, S.10
Chen, K.11
Li, Y.12
Liu, X.13
Xu, J.14
-
74
-
-
84876463939
-
Breathing-in epigenetic change with vitamin C
-
Monfort A, Wutz A. Breathing-in epigenetic change with vitamin C. EMBO Rep. 2013; 14: 337-46.
-
(2013)
EMBO Rep
, vol.14
, pp. 337-346
-
-
Monfort, A.1
Wutz, A.2
-
75
-
-
82755187396
-
The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner
-
Wang T, Chen K, Zeng X, Yang J, Wu Y, Shi X, Qin B, Zeng L, Esteban MA, Pan G, Pei D. The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner. Cell Stem Cell. 2011; 9: 575-87.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 575-587
-
-
Wang, T.1
Chen, K.2
Zeng, X.3
Yang, J.4
Wu, Y.5
Shi, X.6
Qin, B.7
Zeng, L.8
Esteban, M.A.9
Pan, G.10
Pei, D.11
-
76
-
-
84931362449
-
Oncometabolic mutation IDH1 R132H confers a metformin-hypersensitive phenotype
-
Cuyàs E, Fernández-Arroyo S, Corominas-Faja B, Rodríguez-Gallego E, Bosch-Barrera J, Martin-Castillo B, De Llorens R, Joven J, Menendez JA. Oncometabolic mutation IDH1 R132H confers a metformin-hypersensitive phenotype. Oncotarget. 2015; 6:12279-296. doi: 10.18632/oncotarget.3733.
-
(2015)
Oncotarget
, vol.6
, pp. 12279-12296
-
-
Cuyàs, E.1
Fernández-Arroyo, S.2
Corominas-Faja, B.3
Rodríguez-Gallego, E.4
Bosch-Barrera, J.5
Martin-Castillo, B.6
De Llorens, R.7
Joven, J.8
Menendez, J.A.9
-
77
-
-
84951113266
-
Exploring the Process of Energy Generation in Pathophysiology by Targeted Metabolomics: Performance of a Simple and Quantitative Method
-
Riera-Borrull M, Rodríguez-Gallego E, Hernández-Aguilera A, Luciano F, Ras R, Cuyàs E, Camps J, Segura-Carretero A, Menendez JA, Joven J, Fernández-Arroyo S. Exploring the Process of Energy Generation in Pathophysiology by Targeted Metabolomics: Performance of a Simple and Quantitative Method. J Am Soc Mass Spectrom. 2016;27:168-77.
-
(2016)
J Am Soc Mass Spectrom
, vol.27
, pp. 168-177
-
-
Riera-Borrull, M.1
Rodríguez-Gallego, E.2
Hernández-Aguilera, A.3
Luciano, F.4
Ras, R.5
Cuyàs, E.6
Camps, J.7
Segura-Carretero, A.8
Menendez, J.A.9
Joven, J.10
Fernández-Arroyo, S.11
-
78
-
-
77958133875
-
Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection
-
Gutierrez-Aranda I, Ramos-Mejia V, Bueno C, Munoz-Lopez M, Real PJ, Mácia A, Sanchez L, Ligero G, Garcia-Parez JL, Menendez P. Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection. Stem Cells. 2010; 28: 1568-70.
-
(2010)
Stem Cells
, vol.28
, pp. 1568-1570
-
-
Gutierrez-Aranda, I.1
Ramos-Mejia, V.2
Bueno, C.3
Munoz-Lopez, M.4
Real, P.J.5
Mácia, A.6
Sanchez, L.7
Ligero, G.8
Garcia-Parez, J.L.9
Menendez, P.10
-
79
-
-
66149179125
-
Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine
-
Knoepfler PS. Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine. Stem Cells. 2009; 27: 1050-56.
-
(2009)
Stem Cells
, vol.27
, pp. 1050-1056
-
-
Knoepfler, P.S.1
-
80
-
-
77956634610
-
A call to standardize teratoma assays used to define human pluripotent cell lines
-
Müller FJ, Goldmann J, Löser P, Loring JF. A call to standardize teratoma assays used to define human pluripotent cell lines. Cell Stem Cell. 2010; 6: 412-14.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 412-414
-
-
Müller, F.J.1
Goldmann, J.2
Löser, P.3
Loring, J.F.4
-
81
-
-
84855824670
-
Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency
-
Menendez S, Camus S, Herreria A, Paramonov I, Morera LB, Collado M, Pekarik V, Maceda I, Edel M, Consiglio A, Sanchez A, Li H, Serrano M, Belmonte JC. Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency. Aging Cell. 2012; 11: 41-50.
-
(2012)
Aging Cell
, vol.11
, pp. 41-50
-
-
Menendez, S.1
Camus, S.2
Herreria, A.3
Paramonov, I.4
Morera, L.B.5
Collado, M.6
Pekarik, V.7
Maceda, I.8
Edel, M.9
Consiglio, A.10
Sanchez, A.11
Li, H.12
Serrano, M.13
Belmonte, J.C.14
-
82
-
-
84927732079
-
Stem cells. Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness
-
Katajisto P, Döhla J, Chaffer CL, Pentinmikko N, Marjanovic N, Iqbal S, Zoncu R, Chen W, Weinberg RA, Sabatini DM. Stem cells. Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness. Science. 2015; 348: 340-43.
-
(2015)
Science
, vol.348
, pp. 340-343
-
-
Katajisto, P.1
Döhla, J.2
Chaffer, C.L.3
Pentinmikko, N.4
Marjanovic, N.5
Iqbal, S.6
Zoncu, R.7
Chen, W.8
Weinberg, R.A.9
Sabatini, D.M.10
-
83
-
-
84867740975
-
Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner
-
Frank M, Duvezin-Caubet S, Koob S, Occhipinti A, Jagasia R, Petcherski A, Ruonala MO, Priault M, Salin B, Reichert AS. Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner. Biochim Biophys Acta. 2012; 1823: 2297-2310.
-
(2012)
Biochim Biophys Acta
, vol.1823
, pp. 2297-2310
-
-
Frank, M.1
Duvezin-Caubet, S.2
Koob, S.3
Occhipinti, A.4
Jagasia, R.5
Petcherski, A.6
Ruonala, M.O.7
Priault, M.8
Salin, B.9
Reichert, A.S.10
-
84
-
-
84867540151
-
c-Myc and cancer metabolism
-
Miller DM, Thomas SD, Islam A, Muench D, Sedoris K. c-Myc and cancer metabolism. Clin Cancer Res. 2012; 18: 5546-53.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5546-5553
-
-
Miller, D.M.1
Thomas, S.D.2
Islam, A.3
Muench, D.4
Sedoris, K.5
-
85
-
-
84892598278
-
Antioxidant supplementation reduces genomic aberrations in human induced pluripotent stem cells
-
Ji J, Sharma V, Qi S, Guarch ME, Zhao P, Luo Z, Fan W, Wang Y, Mbabaali F, Neculai D, Esteban MA, McPherson JD, Batada NN. Antioxidant supplementation reduces genomic aberrations in human induced pluripotent stem cells. Stem Cell Reports. 2014; 2: 44-51.
-
(2014)
Stem Cell Reports
, vol.2
, pp. 44-51
-
-
Ji, J.1
Sharma, V.2
Qi, S.3
Guarch, M.E.4
Zhao, P.5
Luo, Z.6
Fan, W.7
Wang, Y.8
Mbabaali, F.9
Neculai, D.10
Esteban, M.A.11
McPherson, J.D.12
Batada, N.N.13
-
86
-
-
77957666255
-
Histone methyl transferases and demethylases; can they link metabolism and transcription?
-
Teperino R, Schoonjans K, Auwerx J. Histone methyl transferases and demethylases; can they link metabolism and transcription? Cell Metab. 2010;12:321-27.
-
(2010)
Cell Metab
, vol.12
, pp. 321-327
-
-
Teperino, R.1
Schoonjans, K.2
Auwerx, J.3
-
87
-
-
84868593544
-
Kinetic analysis of iron-dependent histone demethylases: a-ketoglutarate substrate inhibition and potential relevance to the regulation of histone demethylation in cancer cells
-
Cascella B, Mirica LM. Kinetic analysis of iron-dependent histone demethylases: a-ketoglutarate substrate inhibition and potential relevance to the regulation of histone demethylation in cancer cells. Biochemistry. 2012;51:8699-701.
-
(2012)
Biochemistry
, vol.51
, pp. 8699-8701
-
-
Cascella, B.1
Mirica, L.M.2
-
88
-
-
84902685602
-
Krebs cycle intermediates regulate DNA and histone methylation: epigenetic impact on the aging process
-
Salminen A, Kauppinen A, Hiltunen M, Kaarniranta K. Krebs cycle intermediates regulate DNA and histone methylation: epigenetic impact on the aging process. Ageing Res Rev. 2014;16:45-65.
-
(2014)
Ageing Res Rev
, vol.16
, pp. 45-65
-
-
Salminen, A.1
Kauppinen, A.2
Hiltunen, M.3
Kaarniranta, K.4
-
89
-
-
84925503908
-
Intracellular a-ketoglutarate maintains the pluripotency of embryonic stem cells
-
Carey BW, Finley LW, Cross JR, Allis CD, Thompson CB. Intracellular a-ketoglutarate maintains the pluripotency of embryonic stem cells. Nature. 2015;518:413-16.
-
(2015)
Nature
, vol.518
, pp. 413-416
-
-
Carey, B.W.1
Finley, L.W.2
Cross, J.R.3
Allis, C.D.4
Thompson, C.B.5
-
90
-
-
84860586157
-
Mitochondrial regulation of epigenetics and its role in human diseases
-
Minocherhomji S, Tollefsbol TO, Singh KK. Mitochondrial regulation of epigenetics and its role in human diseases. Epigenetics. 2012;7:326-34.
-
(2012)
Epigenetics
, vol.7
, pp. 326-334
-
-
Minocherhomji, S.1
Tollefsbol, T.O.2
Singh, K.K.3
-
91
-
-
84898845550
-
Krebs cycle dysfunction shapes epigenetic landscape of chromatin: novel insights into mitochondrial regulation of aging process
-
Salminen A, Kaarniranta K, Hiltunen M, Kauppinen A. Krebs cycle dysfunction shapes epigenetic landscape of chromatin: novel insights into mitochondrial regulation of aging process. Cell Signal. 2014;26:1598-1603.
-
(2014)
Cell Signal
, vol.26
, pp. 1598-1603
-
-
Salminen, A.1
Kaarniranta, K.2
Hiltunen, M.3
Kauppinen, A.4
-
92
-
-
84964570084
-
Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity
-
Merkwirth C, Jovaisaite V, Durieux J, Matilainen O, Jordan SD, Quiros PM, Steffen KK, Williams EG, Mouchiroud L, Tronnes SU, Murillo V, Wolff SC, Shaw RJ, Auwerx J, Dillin A. Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity. Cell. 2016; 165:1209-23.
-
(2016)
Cell
, vol.165
, pp. 1209-1223
-
-
Merkwirth, C.1
Jovaisaite, V.2
Durieux, J.3
Matilainen, O.4
Jordan, S.D.5
Quiros, P.M.6
Steffen, K.K.7
Williams, E.G.8
Mouchiroud, L.9
Tronnes, S.U.10
Murillo, V.11
Wolff, S.C.12
Shaw, R.J.13
Auwerx, J.14
Dillin, A.15
-
93
-
-
84895484925
-
Chemical ablation of tumorinitiating human pluripotent stem cells
-
Ben-David U, Benvenisty N. Chemical ablation of tumorinitiating human pluripotent stem cells. Nat Protoc. 2014; 9: 729-40.
-
(2014)
Nat Protoc
, vol.9
, pp. 729-740
-
-
Ben-David, U.1
Benvenisty, N.2
-
94
-
-
84873572366
-
Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a highthroughput screen
-
Ben-David U, Gan QF, Golan-Lev T, Arora P, Yanuka O, Oren YS, Leikin-Frenkel A, Graf M, Garippa R, Boehringer M, Gromo G, Benvenisty N. Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a highthroughput screen. Cell Stem Cell. 2013; 12: 167-79.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 167-179
-
-
Ben-David, U.1
Gan, Q.F.2
Golan-Lev, T.3
Arora, P.4
Yanuka, O.5
Oren, Y.S.6
Leikin-Frenkel, A.7
Graf, M.8
Garippa, R.9
Boehringer, M.10
Gromo, G.11
Benvenisty, N.12
-
95
-
-
84870821967
-
Suicide gene-mediated ablation of tumor-initiating mouse pluripotent stem cells
-
Chen F, Cai B, Gao Y, Yuan X, Cheng F, Wang T, Jiang M, Zhou Y, Lahn BT, Li W, Xiang AP. Suicide gene-mediated ablation of tumor-initiating mouse pluripotent stem cells. Biomaterials. 2013; 34: 1701-11.
-
(2013)
Biomaterials
, vol.34
, pp. 1701-1711
-
-
Chen, F.1
Cai, B.2
Gao, Y.3
Yuan, X.4
Cheng, F.5
Wang, T.6
Jiang, M.7
Zhou, Y.8
Lahn, B.T.9
Li, W.10
Xiang, A.P.11
-
96
-
-
84883386827
-
Inhibition of pluripotent stem cell-derived teratoma formation by small molecules
-
Lee MO, Moon SH, Jeong HC, Yi JY, Lee TH, Shim SH, Rhee YH, Lee SH, Oh SJ, Lee MY, Han MJ, Cho YS, Chung HM, Kim KS, Cha HJ. Inhibition of pluripotent stem cell-derived teratoma formation by small molecules. Proc Natl Acad Sci U S A. 2013; 110: E3281-E3290.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. E3281-E3290
-
-
Lee, M.O.1
Moon, S.H.2
Jeong, H.C.3
Yi, J.Y.4
Lee, T.H.5
Shim, S.H.6
Rhee, Y.H.7
Lee, S.H.8
Oh, S.J.9
Lee, M.Y.10
Han, M.J.11
Cho, Y.S.12
Chung, H.M.13
Kim, K.S.14
Cha, H.J.15
-
97
-
-
84964054269
-
Metabolic control of cancer cell stemness: Lessons from iPS cells
-
Menendez JA. Metabolic control of cancer cell stemness: Lessons from iPS cells. Cell Cycle. 2015; 14: 3801-11.
-
(2015)
Cell Cycle
, vol.14
, pp. 3801-3811
-
-
Menendez, J.A.1
-
98
-
-
80052749542
-
An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells
-
Tang C, Lee AS, Volkmer JP, Sahoo D, Nag D, Mosley AR, Inlay MA, Ardehali R, Chavez SL, Pera RR, Behr B, Wu JC, Weissman IL, Drukker M. An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. Nat Biotechnol. 2011; 29: 829-34.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 829-834
-
-
Tang, C.1
Lee, A.S.2
Volkmer, J.P.3
Sahoo, D.4
Nag, D.5
Mosley, A.R.6
Inlay, M.A.7
Ardehali, R.8
Chavez, S.L.9
Pera, R.R.10
Behr, B.11
Wu, J.C.12
Weissman, I.L.13
Drukker, M.14
-
99
-
-
84946478936
-
Atg5-independent autophagy regulates mitochondrial clearance and is essential for iPSC reprogramming
-
Ma T, Li J, Xu Y, Yu C, Xu T, Wang H, Liu K, Cao N, Nie BM, Zhu SY, Xu S, Li K, Wei WG, Wu Y, Guan KL, Ding S. Atg5-independent autophagy regulates mitochondrial clearance and is essential for iPSC reprogramming. Nat Cell Biol. 2015; 17: 1379-87.
-
(2015)
Nat Cell Biol
, vol.17
, pp. 1379-1387
-
-
Ma, T.1
Li, J.2
Xu, Y.3
Yu, C.4
Xu, T.5
Wang, H.6
Liu, K.7
Cao, N.8
Nie, B.M.9
Zhu, S.Y.10
Xu, S.11
Li, K.12
Wei, W.G.13
Wu, Y.14
Guan, K.L.15
Ding, S.16
-
100
-
-
84938739650
-
Evolution of Mitochondria as Signaling Organelles
-
Chandel NS. Evolution of Mitochondria as Signaling Organelles. Cell Metab. 2015;22:204-06.
-
(2015)
Cell Metab
, vol.22
, pp. 204-206
-
-
Chandel, N.S.1
-
101
-
-
84957439277
-
TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions
-
Martínez-Reyes I, Diebold LP, Kong H, Schieber M, Huang H, Hensley CT, Mehta MM, Wang T, Santos JH, Woychik R, Dufour E, Spelbrink JN, Weinberg SE, Zhao Y, DeBerardinis RJ, Chandel NS. TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions. Mol Cell. 2016;61:199-209.
-
(2016)
Mol Cell
, vol.61
, pp. 199-209
-
-
Martínez-Reyes, I.1
Diebold, L.P.2
Kong, H.3
Schieber, M.4
Huang, H.5
Hensley, C.T.6
Mehta, M.M.7
Wang, T.8
Santos, J.H.9
Woychik, R.10
Dufour, E.11
Spelbrink, J.N.12
Weinberg, S.E.13
Zhao, Y.14
DeBerardinis, R.J.15
Chandel, N.S.16
-
102
-
-
84958751426
-
Activation of the methylation cycle in cells reprogrammed into a stem cell-like state
-
Fernández-Arroyo S, Cuyàs E, Bosch-Barrera J, Alarcón T, Joven J, Menendez JA. Activation of the methylation cycle in cells reprogrammed into a stem cell-like state. Oncoscience. 2016;2:958-67.
-
(2016)
Oncoscience
, vol.2
, pp. 958-967
-
-
Fernández-Arroyo, S.1
Cuyàs, E.2
Bosch-Barrera, J.3
Alarcón, T.4
Joven, J.5
Menendez, J.A.6
|