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Volumn 541, Issue 7635, 2017, Pages 41-45

Targeting metastasis-initiating cells through the fatty acid receptor CD36

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A; CASPASE 3; CD36 ANTIGEN; HERMES ANTIGEN; NEUTRALIZING ANTIBODY; PALMITIC ACID; SHORT HAIRPIN RNA; TRANSCRIPTOME;

EID: 85016165255     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature20791     Document Type: Article
Times cited : (1019)

References (69)
  • 1
    • 84896113460 scopus 로고    scopus 로고
    • Metasatic stem cells: Sources, niches, and vital pathways
    • Oskarsson, T., Batlle, E. & Massagué, J. Metastatic stem cells: sources, niches, and vital pathways. Cell Stem Cell 14, 306-321 (2014).
    • (2014) Cell Stem Cel , vol.14 , pp. 306-321
    • Oskarsson, T.1    Batlle, E.2    Massagué, J.3
  • 2
    • 81255157465 scopus 로고    scopus 로고
    • Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
    • Nieman, K. M. et al. Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nat. Med. 17, 1498-1503 (2011).
    • (2011) Nat. Med , vol.17 , pp. 1498-1503
    • Nieman, K.M.1
  • 4
    • 84883377982 scopus 로고    scopus 로고
    • Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma
    • Zhang, X. H. et al. Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma. Cell 154, 1060-1073 (2013).
    • (2013) Cel , vol.154 , pp. 1060-1073
    • Zhang, X.H.1
  • 5
    • 84869021181 scopus 로고    scopus 로고
    • Dependency of colorectal cancer on a TGF-driven program in stromal cells for metastasis initiation
    • Calon, A. et al. Dependency of colorectal cancer on a TGF-driven program in stromal cells for metastasis initiation. Cancer Cell 22, 571-584 (2012).
    • (2012) Cancer Cel , vol.22 , pp. 571-584
    • Calon, A.1
  • 6
    • 84888328750 scopus 로고    scopus 로고
    • VEGFargets the tumour cell
    • Goel, H. L. & Mercurio, A. M. VEGF targets the tumour cell. Nat. Rev. Cancer 13, 871-882 (2013).
    • (2013) Nat. Rev. Cance , vol.13 , pp. 871-882
    • Goel, H.L.1    Mercurio, A.M.2
  • 7
    • 84908118492 scopus 로고    scopus 로고
    • Analysis of tumour-and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S
    • Sevenich, L. et al. Analysis of tumour-and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S. Nat. Cell Biol. 16, 876-888 (2014).
    • (2014) Nat. Cell Biol , vol.16 , pp. 876-888
    • Sevenich, L.1
  • 8
    • 84896690172 scopus 로고    scopus 로고
    • Serpins promote cancer cell survival and vascular co-option in brain metastasis
    • Valiente, M. et al. Serpins promote cancer cell survival and vascular co-option in brain metastasis. Cell 156, 1002-1016 (2014).
    • (2014) Cel , vol.156 , pp. 1002-1016
    • Valiente, M.1
  • 9
    • 84928174677 scopus 로고    scopus 로고
    • Therapy-induced tumour secretomes promote resistance and tumour progression
    • Obenauf, A. C. et al. Therapy-induced tumour secretomes promote resistance and tumour progression. Nature 520, 368-372 (2015).
    • (2015) Natur , vol.520 , pp. 368-372
    • Obenauf, A.C.1
  • 10
    • 83455208311 scopus 로고    scopus 로고
    • VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging 4 1-positive osteoclast progenitors
    • Lu, X. et al. VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging 4 1-positive osteoclast progenitors. Cancer Cell 20, 701-714 (2011).
    • (2011) Cancer Cel , vol.20 , pp. 701-714
    • Lu, X.1
  • 11
    • 80054725681 scopus 로고    scopus 로고
    • Hage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs
    • Chen, Q., Zhang, X. H. & Massagué, J. Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs. Cancer Cell 20, 538-549 (2011).
    • (2011) Cancer Cel , vol.20 , pp. 538-549
    • Chen, Q.1    Zhang, X.H.2    Macro, M.J.3
  • 12
    • 79953147370 scopus 로고    scopus 로고
    • A perspective on cancer cell metastasis
    • Chaffer, C. L. & Weinberg, R. A. A perspective on cancer cell metastasis. Scienc., 331 ,1559-1564.,2011).
    • (2011) Scien , vol.331 , pp. 1559-1564
    • Chaffer, C.L.1    Weinberg, R.A.2
  • 13
    • 84862007577 scopus 로고    scopus 로고
    • Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
    • Peinado, H. et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat. Med. 18, 883-891 (2012).
    • (2012) Nat. Med , vol.18 , pp. 883-891
    • Peinado, H.1
  • 14
    • 79960117895 scopus 로고    scopus 로고
    • Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs
    • Oskarsson, T. et al. Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs. Nat. Med. 17, 867-874 (2011).
    • (2011) Nat. Med , vol.17 , pp. 867-874
    • Oskarsson, T.1
  • 15
    • 84905381214 scopus 로고    scopus 로고
    • Mour-induced systemic environment as a critical regulator of cancer progression and metastasis
    • McAllister, S. S. & Weinberg, R. A. The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis. Nat. Cell Biol. 16, 717-727 (2014).
    • (2014) Nat. Cell Biol , vol.16 , pp. 717-727
    • McAllister, S.S.1    Weinberg The A R, T.2
  • 16
    • 84897954522 scopus 로고    scopus 로고
    • The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
    • Paolino, M. et al. The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells. Nature 507, 508-512 (2014).
    • (2014) Natur , vol.507 , pp. 508-512
    • Paolino, M.1
  • 17
    • 84950299450 scopus 로고    scopus 로고
    • Phils support lung colonization of metastasis-initiating breast cancer cells
    • Wculek, S. K. & Malanchi, I. Neutrophils support lung colonization of metastasis-initiating breast cancer cells. Nature 528, 413-417 (2015).
    • (2015) Natur , vol.528 , pp. 413-417
    • Wculek, S.K.1    Neutr, M.I.2
  • 18
    • 84930225521 scopus 로고    scopus 로고
    • In vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior
    • Zomer, A. et al. In vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior. Cell 161, 1046-1057 (2015).
    • (2015) Cel , vol.161 , pp. 1046-1057
    • Zomer, A.1
  • 19
    • 84898476721 scopus 로고    scopus 로고
    • Cancer-secreted MIR-105 destroys vascular endothelial Barriers to promote metastasis
    • Zhou, W. et al. Cancer-secreted MIR-105 destroys vascular endothelial Barriers to promote metastasis. Cancer Cell 25, 501-515 (2014).
    • (2014) Cancer Cel , vol.25 , pp. 501-515
    • Zhou, W.1
  • 20
    • 84901439825 scopus 로고    scopus 로고
    • A novel method for monitoring tumor proliferation in vivo using fluorescent dye DiD
    • Yumoto, K., Berry, J. E., Taichman, R. S. & Shiozawa, Y. A novel method for monitoring tumor proliferation in vivo using fluorescent dye DiD. Cytometry .,85 ,.548-555., 2014).
    • (2014) Cytom. Try A , vol.85 , pp. 548-555
    • Yumoto, K.1    Berry, J.E.2    Taichman, R.S.3    Shiozawa, Y.4
  • 21
    • 33846512398 scopus 로고    scopus 로고
    • Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
    • Prince, M. E. et al. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc. Natl Acad. Sci. USA 104, 973-978 (2007).
    • (2007) Proc. Natl Acad. Sci. US , vol.104 , pp. 973-978
    • Prince, M.E.1
  • 22
    • 35349017905 scopus 로고    scopus 로고
    • Stemell patterns in cell lines derived from head and neck squamous cell carcinoma
    • Harper, L. J., Piper, K., Common, J., Fortune, F. & Mackenzie, I. C. Stem cell patterns in cell lines derived from head and neck squamous cell carcinoma. J. Oral Pathol. Med. 36, 594-603 (2007).
    • (2007) J. Oral Pathol. Med , vol.36 , pp. 594-603
    • Harper, L.J.1    Piper, K.2    Common, J.3    Fortune, F.4    Mackenzie, I.C.5
  • 23
    • 79960936439 scopus 로고    scopus 로고
    • Cancer stem cells in squamous cell carcinoma switch between two distinct phenotypes that are preferentially migratory or proliferative
    • Biddle, A. et al. Cancer stem cells in squamous cell carcinoma switch between two distinct phenotypes that are preferentially migratory or proliferative. Cancer Res. 71, 5317-5326 (2011).
    • (2011) Cancer Res , vol.71 , pp. 5317-5326
    • Biddle, A.1
  • 24
    • 0034693232 scopus 로고    scopus 로고
    • Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice
    • Coburn, C. T. et al. Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice. J. Biol. Chem. 275, 32523-32529 (2000).
    • (2000) J. Biol. Chem , vol.275 , pp. 32523-32529
    • Coburn, C.T.1
  • 25
    • 0033578604 scopus 로고    scopus 로고
    • Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin
    • Ibrahimi, A. et al. Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin. J. Biol. Chem. 274, 26761-26766 (1999).
    • (1999) J. Biol. Chem , vol.274 , pp. 26761-26766
    • Ibrahimi, A.1
  • 26
    • 84904631280 scopus 로고    scopus 로고
    • Strucure-function of CD36 and importance of fatty acid signal transduction in fat metabolism
    • Pepino, M. Y., Kuda, O., Samovski, D. & Abumrad, N. A. Structure-function of CD36 and importance of fatty acid signal transduction in fat metabolism. Annu. Rev. Nutr. 34, 281-303 (2014).
    • (2014) Annu. Rev. Nutr , vol.34 , pp. 281-303
    • Pepino, M.Y.1    Kuda, O.2    Samovski, D.3    Abumrad, N.A.4
  • 27
    • 77956629388 scopus 로고    scopus 로고
    • Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis
    • Ellis, J. M. et al. Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis. Cell Metab. 12, 53-64 (2010).
    • (2010) Cell Metab , vol.12 , pp. 53-64
    • Ellis, J.M.1
  • 28
    • 28644431994 scopus 로고    scopus 로고
    • Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration
    • Kermorvant-Duchemin, E. et al. Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration. Nat. Med. 11, 1339-1345 (2005).
    • (2005) Nat. Med , vol.11 , pp. 1339-1345
    • Kermorvant-Duchemin, E.1
  • 29
    • 74949084316 scopus 로고    scopus 로고
    • Membrne fatty acid transporters as regulators of lipid metabolism: Implications for metabolic disease
    • Glatz, J. F., Luiken, J. J. & Bonen, A. Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease. Physiol. Rev. 90, 367-417 (2010).
    • (2010) Physiol. Rev , vol.90 , pp. 367-417
    • Glatz, J.F.1    Luiken, J.J.2    Bonen, A.3
  • 30
    • 85016359800 scopus 로고    scopus 로고
    • Compaative studies of vertebrate platelet glycoprotein 4 (CD36
    • Holmes, R. S. Comparative studies of vertebrate platelet glycoprotein 4 (CD36). Biomolecules 2, 389-414 (2012).
    • (2012) Biomolecule , vol.2 , pp. 389-414
    • Holmes, R.S.1
  • 31
    • 79960825294 scopus 로고    scopus 로고
    • Pathoenic role of scavenger receptor CD36 in the metabolic syndrome and diabetes
    • Kennedy, D. J. & Kashyap, S. R. Pathogenic role of scavenger receptor CD36 in the metabolic syndrome and diabetes. Metab. Syndr. Relat. Disord. 9, 239-245 (2011).
    • (2011) Metab. Syndr. Relat. Disord , vol.9 , pp. 239-245
    • Kennedy, D.J.1    Kashyap, S.R.2
  • 32
    • 4344598315 scopus 로고    scopus 로고
    • Metabolic enzymes: Emerging drug targets for the treatment of obesity
    • Shi, Y. & Burn, P. Lipid metabolic enzymes: emerging drug targets for the treatment of obesity. Nat. Rev. Drug Discov. 3, 695-710 (2004).
    • (2004) Nat. Rev. Drug Discov , vol.3 , pp. 695-710
    • Shi, Y.1    Lipid, B.P.2
  • 33
    • 33750576411 scopus 로고    scopus 로고
    • Activtion of CD36 inhibits and induces regression of inflammatory corneal neovascularization
    • Mwaikambo, B. R., Sennlaub, F., Ong, H., Chemtob, S. & Hardy, P. Activation of CD36 inhibits and induces regression of inflammatory corneal neovascularization. Invest. Ophthalmol. Vis. Sci. 47, 4356-4364 (2006).
    • (2006) Invest. Ophthalmol. Vis. Sci , vol.47 , pp. 4356-4364
    • Mwaikambo, B.R.1    Sennlaub, F.2    Ong, H.3    Chemtob, S.4    Hardy, P.5
  • 34
    • 84879103346 scopus 로고    scopus 로고
    • Molecular basis of antiangiogenic thrombospondin-1 type 1 repeat domain interactions with CD36
    • Klenotic, P. A. et al. Molecular basis of antiangiogenic thrombospondin-1 type 1 repeat domain interactions with CD36. Arterioscler. Thromb. Vasc. Biol. 33, 1655-1662 (2013).
    • (2013) Arterioscler. Thromb. Vasc. Biol. , vol.33 , pp. 1655-1662
    • Klenotic, P.A.1
  • 35
    • 84952894855 scopus 로고    scopus 로고
    • Genetc alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers
    • Nath, A. & Chan, C. Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers. Sci. Rep. 6, 18669 (2016).
    • (2016) Sci. Rep , vol.6 , pp. 18669
    • Nath, A.1    Chan, C.2
  • 36
    • 78651335627 scopus 로고    scopus 로고
    • Metablic fuels: Regulating fluxes to select mix
    • Weber, J. M. Metabolic fuels: regulating fluxes to select mix. J. Exp. Biol. 214, 286-294 (2011).
    • (2011) J. Exp. Biol , vol.214 , pp. 286-294
    • Weber, J.M.1
  • 37
    • 84941243013 scopus 로고    scopus 로고
    • Distinct EMT programs control normal mammary stem cells and tumour-initiating cells
    • Ye, X. et al. Distinct EMT programs control normal mammary stem cells and tumour-initiating cells. Nature 525, 256-260 (2015).
    • (2015) Natur , vol.525 , pp. 256-260
    • Ye, X.1
  • 38
    • 84951310639 scopus 로고    scopus 로고
    • Mesenchymal cancer cell-stroma crosstalk promotes niche activation, epithelial reversion, and metastatic colonization
    • Del Pozo Martin, Y. et al. Mesenchymal cancer cell-stroma crosstalk promotes niche activation, epithelial reversion, and metastatic colonization. Cell Reports 13, 2456-2469 (2015).
    • (2015) Cell Report , vol.13 , pp. 2456-2469
    • Del Pozo Martin, Y.1
  • 39
    • 84947274381 scopus 로고    scopus 로고
    • Micronvironment in metastasis: Roadblocks and supportive niches
    • Pein, M. & Oskarsson, T. Microenvironment in metastasis: roadblocks and supportive niches. Am. J. Physiol. Cell Physiol. 309, C627-C638 (2015).
    • (2015) Am. J. Physiol. Cell Physiol , vol.309 , pp. C627-C638
    • Pein, M.1    Oskarsson, T.2
  • 40
    • 84948429460 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
    • Fischer, K. R. et al. Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance. Nature 527, 472-476 (2015).
    • (2015) Natur , vol.527 , pp. 472-476
    • Fischer, K.R.1
  • 41
    • 84948407218 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
    • Zheng, X. et al. Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. Nature 527, 525-530 (2015).
    • (2015) Natur , vol.527 , pp. 525-530
    • Zheng, X.1
  • 42
    • 84860578009 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells
    • Celia-Terrassa, T. et al. Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells. J. Clin. Invest. 122, 1849-1868 (2012).
    • (2012) J. Clin. Invest , vol.122 , pp. 1849-1868
    • Celia-Terrassa, T.1
  • 43
    • 84955336478 scopus 로고    scopus 로고
    • Enhanced MAF oncogene expression and breast cancer bone metastasis
    • Pavlovic, M. et al. Enhanced MAF oncogene expression and breast cancer bone metastasis. J. Natl Cancer Inst. 107, djv256 (2015).
    • (2015) J. Natl Cancer Inst , vol.107 , pp. djv256
    • Pavlovic, M.1
  • 44
    • 84902578963 scopus 로고    scopus 로고
    • Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression
    • Hale, J. S. et al. Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression. Stem Cells 32, 1746-1758 (2014).
    • (2014) Stem Cell , vol.32 , pp. 1746-1758
    • Hale, J.S.1
  • 46
    • 84908011236 scopus 로고    scopus 로고
    • Rewiring of an epithelial differentiation factor, MIR-203, to inhibit human squamous cell carcinoma metastasis
    • Benaich, N. et al. Rewiring of an epithelial differentiation factor, MIR-203, to inhibit human squamous cell carcinoma metastasis. Cell Reports 9, 104-117 (2014).
    • (2014) Cell Report , vol.9 , pp. 104-117
    • Benaich, N.1
  • 48
    • 73149110562 scopus 로고    scopus 로고
    • Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content
    • Pece, S. et al. Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. Cell 140, 62-73 (2010).
    • (2010) Cel , vol.140 , pp. 62-73
    • Pece, S.1
  • 49
    • 77952502408 scopus 로고    scopus 로고
    • A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth
    • Roesch, A. et al. A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth. Cell 141, 583-594 (2010).
    • (2010) Cel , vol.141 , pp. 583-594
    • Roesch, A.1
  • 50
    • 84856044714 scopus 로고    scopus 로고
    • Analysis of marker-defined HNSCC subpopulations reveals a dynamic regulation of tumor initiating properties
    • Bragado, P. et al. Analysis of marker-defined HNSCC subpopulations reveals a dynamic regulation of tumor initiating properties. PLoS One 7, e29974 (2012).
    • (2012) PLoS on , vol.7 , pp. e29974
    • Bragado, P.1
  • 51
    • 84860642507 scopus 로고    scopus 로고
    • The PSA(-/lo) prostate cancer cell population harbors selfrenewing long-term tumor-propagating cells that resist castration
    • Qin, J. et al. The PSA(-/lo) prostate cancer cell population harbors selfrenewing long-term tumor-propagating cells that resist castration. Cell Stem Cell 10, 556-569 (2012).
    • (2012) Cell Stem Cel , vol.10 , pp. 556-569
    • Qin, J.1
  • 52
    • 64349109459 scopus 로고    scopus 로고
    • Mouse models of human AML accurately predict chemotherapy response
    • Zuber, J. et al. Mouse models of human AML accurately predict chemotherapy response. Genes Dev. 23, 877-889 (2009).
    • (2009) Genes Dev , vol.23 , pp. 877-889
    • Zuber, J.1
  • 53
    • 41549111171 scopus 로고    scopus 로고
    • Sensitivity of squamous cell carcinoma lymph node metastases to herpes oncolytic therapy
    • Yu, Z. et al. Sensitivity of squamous cell carcinoma lymph node metastases to herpes oncolytic therapy. Clin. Cancer Res. 14, 1897-1904 (2008).
    • (2008) Clin. Cancer Res , vol.14 , pp. 1897-1904
    • Yu, Z.1
  • 54
    • 33244483352 scopus 로고    scopus 로고
    • OP9 mouse stromal cells rapidly differentiate into adipocytes: Characterization of a useful new model of adipogenesis
    • Wolins, N. E. et al. OP9 mouse stromal cells rapidly differentiate into adipocytes: characterization of a useful new model of adipogenesis. J. Lipid Res. 47, 450-460 (2006).
    • (2006) J. Lipid Res , vol.47 , pp. 450-460
    • Wolins, N.E.1
  • 55
    • 67650444760 scopus 로고    scopus 로고
    • ELDA:Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
    • Hu, Y. & Smyth, G. K. ELDA: extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays. J. Immunol. Methods 347, 70-78 (2009).
    • (2009) J. Immunol. Method , vol.347 , pp. 70-78
    • Hu, Y.1    Smyth, G.K.2
  • 56
    • 59749096851 scopus 로고    scopus 로고
    • Isolaion and culture of epithelial stem cells
    • Nowak, J. A. & Fuchs, E. Isolation and culture of epithelial stem cells. Methods Mol. Biol. 482, 215-232 (2009).
    • (2009) Methods Mol. Biol , vol.482 , pp. 215-232
    • Nowak, J.A.1    Fuchs, E.2
  • 57
    • 81555212599 scopus 로고    scopus 로고
    • Use oBODIPY (493/503) to visualize intramuscular lipid droplets in skeletal muscle
    • S9pangenburg, E. E., Pratt, S. J., Wohlers, L. M. & Lovering, R. M. Use of BODIPY (493/503) to visualize intramuscular lipid droplets in skeletal muscle. J. Biomed. Biotechnol. 2011, 598358 (2011).
    • (2011) J. Biomed. Biotechnol , vol.2011 , pp. 598358
    • Spangenburg, E.E.1    Pratt, S.J.2    Wohlers, L.M.3    Lovering, R.M.4
  • 58
    • 78650847554 scopus 로고    scopus 로고
    • Accurate expression profiling of very small cell populations
    • Gonzalez-Roca, E. et al. Accurate expression profiling of very small cell populations. PLoS One 5, e14418 (2010).
    • (2010) PLoS One , vol.5 , pp. e14418
    • Gonzalez-Roca, E.1
  • 59
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization, and summaries of high density oligonucleotide array probe level data
    • Irizarry, R. A. et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4, 249-264 (2003).
    • (2003) Biostatistics , vol.4 , pp. 249-264
    • Irizarry, R.A.1
  • 61
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: Open software development for computational biology and bioinformatics
    • Gentleman, R. C. et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 5, R80 (2004).
    • (2004) Genome Biol. , vol.5 , pp. R80
    • Gentleman, R.C.1
  • 63
    • 85016136703 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini, Y. H. Y. Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing. J. R. Stat. Soc. B 57, 289-300 (1995).
    • (1995) J. R. Stat. Soc. B , vol.57 , pp. 289-300
    • Benjamini, Y.H.Y.1
  • 64
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian, A. et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl Acad. Sci. USA 102,15545-15550 .2005
    • (2005) Proc. Natl Acad. Sci. US , vol.102 , pp. 15545-15550
    • Subramanian, A.1
  • 66
    • 33747884345 scopus 로고    scopus 로고
    • Genexpression omnibus: Microarray data storage, submission, retrieval, and analysis
    • Barrett, T. & Edgar, R. Gene expression omnibus: microarray data storage, submission, retrieval, and analysis. Methods Enzymol. 411, 352-369 (2006).
    • (2006) Methods Enzymol , vol.411 , pp. 352-369
    • Barrett, T.1    Edgar, R.2
  • 67
    • 84875740314 scopus 로고    scopus 로고
    • Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
    • Gao, J. et al. Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci. Signal. 6, pl1 (2013).
    • (2013) Sci. Signal , vol.6 , pp. pl1
    • Gao, J.1
  • 68
    • 84866002291 scopus 로고    scopus 로고
    • The cBio cancer genomics portal: An open platform for exploring multidimensional cancer genomics data
    • Cerami, E. et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov. 2, 401-404 (2012).
    • (2012) Cancer Discov , vol.2 , pp. 401-404
    • Cerami, E.1
  • 69
    • 84882958819 scopus 로고    scopus 로고
    • Cancer Genome Atlas Network. Compr hensive molecular portraits of human breast tumours
    • Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature 490, 61-70 (2012).
    • (2012) Natur , vol.490 , pp. 61-70


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