Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

eLife

Volumn 5, Issue NOVEMBER2016, 2016, Pages

  Rojansky, Rebecca ^a   Cha, Moon Yong ^a   Chan, David C ^a  

^a California Institute of Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR P62; ADAPTOR PROTEIN; LENTIVIRUS VECTOR; OUTER MEMBRANE PROTEIN; OUTER MEMBRANE PROTEIN FIS1; PARKIN; RETROVIRUS VECTOR; SHORT HAIRPIN RNA; TBC1D15 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; FIS1 PROTEIN, MOUSE; GTF2H1 PROTEIN, MOUSE; MITOCHONDRIAL PROTEIN; MUL1 PROTEIN, MOUSE; PROTEIN KINASE; PTEN-INDUCED PUTATIVE KINASE; TRANSCRIPTION FACTOR; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EXTRACHROMOSOMAL INHERITANCE; FEMALE; FIBROBLAST CULTURE; FLUORESCENCE MICROSCOPY; GENE DISRUPTION; GENE EXPRESSION REGULATION; MALE; MEMBRANE DEPOLARIZATION; MICROINJECTION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOPHAGY; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PROTEIN PROTEIN INTERACTION; SPERMATOCYTE; WESTERN BLOTTING; ANIMAL; GENETICS; HUMAN; MAMMALIAN EMBRYO; MITOCHONDRION; PATERNAL INHERITANCE;

ANIMALS; EMBRYO, MAMMALIAN; HUMANS; MICE; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; MITOCHONDRIAL PROTEINS; PATERNAL INHERITANCE; PROTEIN KINASES; TRANSCRIPTION FACTORS; UBIQUITIN-PROTEIN LIGASES;

EID: 85000919223     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.17896     Document Type: Article

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