Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 16, 2007, Pages 6794-6799

  Diwan, Abhinav ^a   Koesters, Andrew G ^a   Odley, Amy M ^a   Pushkaran, Suvarnamala ^a   Baines, Christopher P ^a   Spike, Benjamin T ^b   Daria, Diedre ^a   Jegga, Anil G ^a   Geiger, Hartmut ^a   Aronow, Bruce J ^a   Molkentin, Jeffery D ^a   Macleod, Kay F ^b   Kalfa, Theodosia A ^a   Dorn II, Gerald W ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Apoptosis; Bcl2 proteins; Erythropoietin; Polycythemia vera

Indexed keywords

BH3 PROTEIN; CALCIUM IONOPHORE; CYTOKINE; ERYTHROPOIETIN; PROTEIN BCL XL; PROTEIN NIX; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; MEMBRANE PROTEIN; MITOCHONDRIAL PROTEIN; NIX PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BLOOD OXYGEN TENSION; BONE MARROW; CELL CULTURE; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; CULTURE MEDIUM; ERYTHROBLAST; ERYTHROBLASTOSIS; ERYTHROCYTE; ERYTHROCYTE COUNT; ERYTHROID CELL; ERYTHROPOIESIS; GENE; GENE EXPRESSION PROFILING; HOMEOSTASIS; MOUSE; NIX GENE; NONHUMAN; OXYGEN BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PROTEIN INDUCTION; RETICULOCYTOSIS; SPLENOMEGALY; THROMBOCYTE COUNT; THROMBOCYTOSIS; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; C57BL MOUSE; ERYTHROCYTE DISORDER; GENETICS; INTRACELLULAR MEMBRANE; LIVER MITOCHONDRION; METABOLISM; MOUSE MUTANT; PATHOLOGY; PERMEABILITY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

MUS;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL SURVIVAL; CELLS, CULTURED; ERYTHROBLASTS; ERYTHROCYTES, ABNORMAL; ERYTHROPOIESIS; ERYTHROPOIETIN; INTRACELLULAR MEMBRANES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MITOCHONDRIA, LIVER; MITOCHONDRIAL PROTEINS; PERMEABILITY; SIGNAL TRANSDUCTION;

EID: 34249852766     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0610666104     Document Type: Article

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