-
1
-
-
33646872978
-
Chromatin signatures of pluripotent cell lines
-
Azuara V, Perry P, Sauer S, Spivakov M, Jørgensen HF, John RM, Gouti M, Casanova M, Warnes G, Merkenschlager M, et al. 2006. Chromatin signatures of pluripotent cell lines. Nat Cell Biol 8: 532–538.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 532-538
-
-
Azuara, V.1
Perry, P.2
Sauer, S.3
Spivakov, M.4
Jørgensen, H.F.5
John, R.M.6
Gouti, M.7
Casanova, M.8
Warnes, G.9
Merkenschlager, M.10
-
2
-
-
0017904532
-
Measurement of metabolites in single preimplantation embryos; a new means to study metabolic control in early embryos
-
Barbehenn EK, Wales RG, Lowry OH. 1978. Measurement of metabolites in single preimplantation embryos; a new means to study metabolic control in early embryos. J Embryol Exp Morphol 43: 29–46.
-
(1978)
J Embryol Exp Morphol
, vol.43
, pp. 29-46
-
-
Barbehenn, E.K.1
Wales, R.G.2
Lowry, O.H.3
-
3
-
-
84946711375
-
Lineage-specific profiling delineates the emergence and progression of naive pluripotency in mammalian embryogenesis
-
Boroviak T, Loos R, Lombard P, Okahara J, Behr R, Sasaki E, Nichols J, Smith A, Bertone P. 2015. Lineage-specific profiling delineates the emergence and progression of naive pluripotency in mammalian embryogenesis. Dev Cell 35: 366–382.
-
(2015)
Dev Cell
, vol.35
, pp. 366-382
-
-
Boroviak, T.1
Loos, R.2
Lombard, P.3
Okahara, J.4
Behr, R.5
Sasaki, E.6
Nichols, J.7
Smith, A.8
Bertone, P.9
-
4
-
-
0018548089
-
Requirements for blastocyst development in vitro
-
Brinster RL, Troike DE. 1979. Requirements for blastocyst development in vitro. J Anim Sci 49(Suppl 2): 26–34.
-
(1979)
J Anim Sci
, vol.49
, pp. 26-34
-
-
Brinster, R.L.1
Troike, D.E.2
-
5
-
-
84959246649
-
Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency
-
Carbognin E, Betto RM, Soriano ME, Smith AG, Martello G. 2016. Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency. EMBO J 35: 618–634.
-
(2016)
EMBO J
, vol.35
, pp. 618-634
-
-
Carbognin, E.1
Betto, R.M.2
Soriano, M.E.3
Smith, A.G.4
Martello, G.5
-
6
-
-
84925503908
-
Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
-
Carey BW, Finley LWS, Cross JR, Allis CD, Thompson CB. 2015. Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells. Nature 518: 413–416.
-
(2015)
Nature
, vol.518
, pp. 413-416
-
-
Carey, B.W.1
Finley, L.W.S.2
Cross, J.R.3
Allis, C.D.4
Thompson, C.B.5
-
7
-
-
69249206717
-
MTOR mediates Wnt-induced epidermal stem cell exhaustion and aging
-
Castilho RM, Squarize CH, Chodosh LA, Williams BO, Gutkind JS. 2009. mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging. Cell Stem Cell 5: 279–289.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 279-289
-
-
Castilho, R.M.1
Squarize, C.H.2
Chodosh, L.A.3
Williams, B.O.4
Gutkind, J.S.5
-
8
-
-
49249086654
-
Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells
-
Chen C-T, Shih Y-RV, Kuo TK, Lee OK, Wei Y-H. 2008a. Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells. Stem Cells 26: 960–968.
-
(2008)
Stem Cells
, vol.26
, pp. 960-968
-
-
Chen, C.-T.1
Shih, Y.-R.2
Kuo, T.K.3
Lee, O.K.4
Wei, Y.-H.5
-
9
-
-
53349091768
-
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
-
Chen C, Liu Y, Liu R, Ikenoue T, Guan KL, Liu Y, Zheng P. 2008b. TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J Exp Med 205: 2397–2408.
-
(2008)
J Exp Med
, vol.205
, pp. 2397-2408
-
-
Chen, C.1
Liu, Y.2
Liu, R.3
Ikenoue, T.4
Guan, K.L.5
Liu, Y.6
Zheng, P.7
-
10
-
-
75549090275
-
MTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells
-
Chen C, Liu Y, Liu Y, Zheng P. 2009. mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells. Sci Signal 2: ra75.
-
(2009)
Sci Signal
, vol.2
-
-
Chen, C.1
Liu, Y.2
Liu, Y.3
Zheng, P.4
-
11
-
-
84888372386
-
Vitamin C modulates TET1 function during somatic cell reprogramming
-
Chen J, Guo L, Zhang L, Wu H, Yang J, Liu H, Wang X, Hu X, Gu T, Zhou Z, et al. 2013a. Vitamin C modulates TET1 function during somatic cell reprogramming. Nat Genet 12: 1504–1509.
-
(2013)
Nat Genet
, vol.12
, pp. 1504-1509
-
-
Chen, J.1
Guo, L.2
Zhang, L.3
Wu, H.4
Yang, J.5
Liu, H.6
Wang, X.7
Hu, X.8
Gu, T.9
Zhou, Z.10
-
12
-
-
84871990064
-
H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs
-
Chen J, Liu H, Liu J, Qi J, Wei B, Yang J, Liang H, Chen Y, Chen J, Wu Y, et al. 2013b. H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet 45: 34–42.
-
(2013)
Nat Genet
, vol.45
, pp. 34-42
-
-
Chen, J.1
Liu, H.2
Liu, J.3
Qi, J.4
Wei, B.5
Yang, J.6
Liang, H.7
Chen, Y.8
Chen, J.9
Wu, Y.10
-
13
-
-
36749081539
-
MTOR controls mitochondrial oxidative function through a YY1–PGC-1α riptional complex
-
Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, Mootha VK, Puigserver P. 2007. mTOR controls mitochondrial oxidative function through a YY1–PGC-1α riptional complex. Nature 450: 736–740.
-
(2007)
Nature
, vol.450
, pp. 736-740
-
-
Cunningham, J.T.1
Rodgers, J.T.2
Arlow, D.H.3
Vazquez, F.4
Mootha, V.K.5
Puigserver, P.6
-
14
-
-
59649101100
-
AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development
-
Dasgupta B, Milbrandt J. 2009. AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development. Dev Cell 16: 256–270.
-
(2009)
Dev Cell
, vol.16
, pp. 256-270
-
-
Dasgupta, B.1
Milbrandt, J.2
-
15
-
-
84942134555
-
The pluripotent state in mouse and human
-
Davidson K, Mason EA, Pera MF. 2015. The pluripotent state in mouse and human. Development 142: 3090–3099.
-
(2015)
Development
, vol.142
, pp. 3090-3099
-
-
Davidson, K.1
Mason, E.A.2
Pera, M.F.3
-
16
-
-
0035281979
-
Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis
-
Drummond-Barbosa D, Spradling AC. 2001. Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis. Dev Biol 231: 265–278.
-
(2001)
Dev Biol
, vol.231
, pp. 265-278
-
-
Drummond-Barbosa, D.1
Spradling, A.C.2
-
17
-
-
79251587803
-
Phosphorylation of ULK1 (HATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
-
Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, et al. 2011. Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science 331: 456–461.
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
Gelino, S.4
Kohnz, R.A.5
Mair, W.6
Vasquez, D.S.7
Joshi, A.8
Gwinn, D.M.9
Taylor, R.10
-
18
-
-
0037444772
-
Failure to increase glucose consumption through the pentose-phosphate pathway results in the death of glucose-6-phosphate dehydrogenase gene-deleted mouse embryonic stem cells subjected to oxidative stress
-
Filosa S, Fico A, Paglialunga F, Balestrieri M, Crooke A, Verde P, Abrescia P, Bautista JM, Martini G. 2003. Failure to increase glucose consumption through the pentose-phosphate pathway results in the death of glucose-6-phosphate dehydrogenase gene-deleted mouse embryonic stem cells subjected to oxidative stress. Biochem J 370: 935–943.
-
(2003)
Biochem J
, vol.370
, pp. 935-943
-
-
Filosa, S.1
Fico, A.2
Paglialunga, F.3
Balestrieri, M.4
Crooke, A.5
Verde, P.6
Abrescia, P.7
Bautista, J.M.8
Martini, G.9
-
19
-
-
79960945131
-
Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming
-
Folmes CDL, Nelson TJ, Martinez-Fernandez A, Arrell DK, Lindor JZ, Dzeja PP, Ikeda Y, Perez-Terzic C, Terzic A. 2011. Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming. Cell Metab 14: 264–271.
-
(2011)
Cell Metab
, vol.14
, pp. 264-271
-
-
Folmes, C.D.L.1
Nelson, T.J.2
Martinez-Fernandez, A.3
Arrell, D.K.4
Lindor, J.Z.5
Dzeja, P.P.6
Ikeda, Y.7
Perez-Terzic, C.8
Terzic, A.9
-
20
-
-
84965029450
-
Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia
-
Fukawa T, Yan-Jiang BC, Min-Wen JC, Jun-Hao ET, Huang D, Qian CN, Ong P, Li Z, Chen S, Mak SY, et al. 2016. Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia. Nat Med 22: 666–671.
-
(2016)
Nat Med
, vol.22
, pp. 666-671
-
-
Fukawa, T.1
Yan-Jiang, B.C.2
Min-Wen, J.C.3
Jun-Hao, E.T.4
Huang, D.5
Qian, C.N.6
Ong, P.7
Li, Z.8
Chen, S.9
Mak, S.Y.10
-
21
-
-
78649874959
-
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells
-
Gan B, Hu J, Jiang S, Liu Y, Sahin E, Zhuang L, Fletcher-Sananikone E, Colla S, Wang YA, Chin L, et al. 2010. Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature 468: 701–704.
-
(2010)
Nature
, vol.468
, pp. 701-704
-
-
Gan, B.1
Hu, J.2
Jiang, S.3
Liu, Y.4
Sahin, E.5
Zhuang, L.6
Fletcher-Sananikone, E.7
Colla, S.8
Wang, Y.A.9
Chin, L.10
-
23
-
-
34247259630
-
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α
-
Gerhart-Hines Z, Rodgers JT, Bare O, Lerin C, Kim SH, Mostoslavsky R, Alt FW, Wu Z, Puigserver P. 2007. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α. EMBO J 26: 1913–1923.
-
(2007)
EMBO J
, vol.26
, pp. 1913-1923
-
-
Gerhart-Hines, Z.1
Rodgers, J.T.2
Bare, O.3
Lerin, C.4
Kim, S.H.5
Mostoslavsky, R.6
Alt, F.W.7
Wu, Z.8
Puigserver, P.9
-
24
-
-
62149148156
-
Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration
-
Goessling W, North TE, Loewer S, Lord AM, Lee S, Stoick-Cooper CL, Weidinger G, Puder M, Daley GQ, Moon RT, et al. 2009. Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell 136: 1136–1147.
-
(2009)
Cell
, vol.136
, pp. 1136-1147
-
-
Goessling, W.1
North, T.E.2
Loewer, S.3
Lord, A.M.4
Lee, S.5
Stoick-Cooper, C.L.6
Weidinger, G.7
Puder, M.8
Daley, G.Q.9
Moon, R.T.10
-
25
-
-
84882900207
-
Clueless regulates aPKC activity and promotes self-renewal cell fate in Drosophila lgl mutant larval brains
-
Goh LH, Zhou X, Lee MC, Lin S, Wang H, Luo Y, Yang X. 2013. Clueless regulates aPKC activity and promotes self-renewal cell fate in Drosophila lgl mutant larval brains. Dev Biol 381: 353–364.
-
(2013)
Dev Biol
, vol.381
, pp. 353-364
-
-
Goh, L.H.1
Zhou, X.2
Lee, M.C.3
Lin, S.4
Wang, H.5
Luo, Y.6
Yang, X.7
-
26
-
-
84992406226
-
Glycolytic metabolism plays a functional role in regulating human pluripotent stem cell state
-
Gu W, Gaeta X, Sahakyan A, Chan AB, Hong CS, Kim R, Braas D, Plath K, Lowry WE, Christofk HR. 2016. Glycolytic metabolism plays a functional role in regulating human pluripotent stem cell state. Cell Stem Cell 19: 476–490.
-
(2016)
Cell Stem Cell
, vol.19
, pp. 476-490
-
-
Gu, W.1
Gaeta, X.2
Sahakyan, A.3
Chan, A.B.4
Hong, C.S.5
Kim, R.6
Braas, D.7
Plath, K.8
Lowry, W.E.9
Christofk, H.R.10
-
27
-
-
78649851511
-
The Lkb1 metabolic sensor maintains haematopoietic stem cell survival
-
Gurumurthy S, Xie SZ, Alagesan B, Kim J, Yusuf RZ, Saez B, Tzatsos A, Ozsolak F, Milos P, Ferrari F, et al. 2010. The Lkb1 metabolic sensor maintains haematopoietic stem cell survival. Nature 468: 659–663.
-
(2010)
Nature
, vol.468
, pp. 659-663
-
-
Gurumurthy, S.1
Xie, S.Z.2
Alagesan, B.3
Kim, J.4
Yusuf, R.Z.5
Saez, B.6
Tzatsos, A.7
Ozsolak, F.8
Milos, P.9
Ferrari, F.10
-
28
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson JE, Frenkel K, Carter CS, et al. 2009. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 460: 392–395.
-
(2009)
Nature
, vol.460
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
Nelson, J.F.4
Astle, C.M.5
Flurkey, K.6
Nadon, N.L.7
Wilkinson, J.E.8
Frenkel, K.9
Carter, C.S.10
-
29
-
-
79551610653
-
Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila
-
Hochmuth CE, Biteau B, Bohmann D, Jasper H. 2011. Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila. Cell Stem Cell 8: 188–199.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 188-199
-
-
Hochmuth, C.E.1
Biteau, B.2
Bohmann, D.3
Jasper, H.4
-
30
-
-
84901316606
-
Cellular mechanisms and physiological consequences of redox-dependent signalling
-
Holmström KM, Finkel T. 2014. Cellular mechanisms and physiological consequences of redox-dependent signalling. Nat Rev Mol Cell Biol 15: 411–421.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 411-421
-
-
Holmström, K.M.1
Finkel, T.2
-
31
-
-
37849019064
-
Diet controls normal and tumorous germline stem cells via insulin-dependent and -independent mechanisms in Drosophila
-
Hsu H-J, LaFever L, Drummond-Barbosa D. 2008. Diet controls normal and tumorous germline stem cells via insulin-dependent and -independent mechanisms in Drosophila. Dev Biol 313: 700–712.
-
(2008)
Dev Biol
, vol.313
, pp. 700-712
-
-
Hsu, H.-J.1
Lafever, L.2
Drummond-Barbosa, D.3
-
32
-
-
46949085597
-
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
-
Huangfu D, Maehr R, Guo W, Eijkelenboom A, Snitow M, Chen AE, Melton DA. 2008. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol 26: 795–797.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 795-797
-
-
Huangfu, D.1
Maehr, R.2
Guo, W.3
Eijkelenboom, A.4
Snitow, M.5
Chen, A.E.6
Melton, D.A.7
-
33
-
-
84868632060
-
A PML–PPARδ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance
-
Ito K, Carracedo A, Weiss D, Arai F, Ala U, Avigan DE, Schafer ZT, Evans RM, Suda T, Lee C-H, et al. 2012. A PML–PPARδ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance. Nat Med 18: 1350–1358.
-
(2012)
Nat Med
, vol.18
, pp. 1350-1358
-
-
Ito, K.1
Carracedo, A.2
Weiss, D.3
Arai, F.4
Ala, U.5
Avigan, D.E.6
Schafer, Z.T.7
Evans, R.M.8
Suda, T.9
Lee, C.-H.10
-
34
-
-
84991108288
-
+ hematopoietic stem cell population relies on mitochondrial clearance
-
+ hematopoietic stem cell population relies on mitochondrial clearance. Science 354: 1156–1160.
-
(2016)
Science
, vol.354
, pp. 1156-1160
-
-
Ito, K.1
Turcotte, R.2
Cui, J.3
Zimmerman, S.E.4
Pinho, S.5
Mizoguchi, T.6
Arai, F.7
Runnels, J.M.8
Alt, C.9
Teruya-Feldstein, J.10
-
35
-
-
0042858325
-
Intermediary metabolism and energetics during murine early embryogenesis
-
Johnson MT, Mahmood S, Patel MS. 2003. Intermediary metabolism and energetics during murine early embryogenesis. J Biol Chem 278: 31457–31460.
-
(2003)
J Biol Chem
, vol.278
, pp. 31457-31460
-
-
Johnson, M.T.1
Mahmood, S.2
Patel, M.S.3
-
36
-
-
84990902034
-
P38α activates purine metabolism to initiate hematopoietic stem/progenitor cell cycling in response to stress
-
Karigane D, Kobayashi H, Morikawa T, Ootomo Y, Sakai M, Nagamatsu G, Kubota Y, Goda N, Matsumoto M, Nishimura EK, et al. 2016. p38α activates purine metabolism to initiate hematopoietic stem/progenitor cell cycling in response to stress. Cell Stem Cell 19: 192–204.
-
(2016)
Cell Stem Cell
, vol.19
, pp. 192-204
-
-
Karigane, D.1
Kobayashi, H.2
Morikawa, T.3
Ootomo, Y.4
Sakai, M.5
Nagamatsu, G.6
Kubota, Y.7
Goda, N.8
Matsumoto, M.9
Nishimura, E.K.10
-
37
-
-
84941024717
-
Oocyte factors suppress mitochondrial polynucleotide phosphorylase to remodel the metabolome and enhance reprogramming
-
Khaw SL, Min-Wen C, Koh CG, Lim B, Shyh-Chang N. 2015. Oocyte factors suppress mitochondrial polynucleotide phosphorylase to remodel the metabolome and enhance reprogramming. Cell Rep 12: 1080–1088.
-
(2015)
Cell Rep
, vol.12
, pp. 1080-1088
-
-
Khaw, S.L.1
Min-Wen, C.2
Koh, C.G.3
Lim, B.4
Shyh-Chang, N.5
-
38
-
-
0030813398
-
Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
-
Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G. 1997. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277: 942–946.
-
(1997)
Science
, vol.277
, pp. 942-946
-
-
Kimura, K.D.1
Tissenbaum, H.A.2
Liu, Y.3
Ruvkun, G.4
-
39
-
-
84864805939
-
Proteomic cornerstones of hematopoietic stem cell differentiation: Distinct signatures of multipotent progenitors and myeloid committed cells
-
Klimmeck D, Hansson J, Raffel S, Vakhrushev SY, Trumpp A, Krijgsveld J. 2012. Proteomic cornerstones of hematopoietic stem cell differentiation: distinct signatures of multipotent progenitors and myeloid committed cells. Mol Cell Proteomics 11: 286–302.
-
(2012)
Mol Cell Proteomics
, vol.11
, pp. 286-302
-
-
Klimmeck, D.1
Hansson, J.2
Raffel, S.3
Vakhrushev, S.Y.4
Trumpp, A.5
Krijgsveld, J.6
-
40
-
-
23644444460
-
Direct control of germline stem cell division and cyst growth by neural insulin in Drosophila
-
LaFever L, Drummond-Barbosa D. 2005. Direct control of germline stem cell division and cyst growth by neural insulin in Drosophila. Science 309: 1071–1073.
-
(2005)
Science
, vol.309
, pp. 1071-1073
-
-
Lafever, L.1
Drummond-Barbosa, D.2
-
41
-
-
0029171260
-
Metabolic control during preimplantation mammalian development
-
Leese HJ. 1995. Metabolic control during preimplantation mammalian development. Hum Reprod Update 1: 63–72.
-
(1995)
Hum Reprod Update
, vol.1
, pp. 63-72
-
-
Leese, H.J.1
-
42
-
-
84956657033
-
Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential
-
Luchsinger LL, de Almeida MJ, Corrigan DJ, Mumau M, Snoeck HW. 2016. Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential. Nature 529: 528–5231.
-
(2016)
Nature
, vol.529
, pp. 528-5231
-
-
Luchsinger, L.L.1
De Almeida, M.J.2
Corrigan, D.J.3
Mumau, M.4
Snoeck, H.W.5
-
43
-
-
77950965653
-
Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes
-
Mali P, Chou BK, Yen J, Ye Z, Zou J, Dowey S, Brodsky RA, Ohm JE, Yu W, et al. 2010. Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells 28: 713–720.
-
(2010)
Stem Cells
, vol.28
, pp. 713-720
-
-
Mali, P.1
Chou, B.K.2
Yen, J.3
Ye, Z.4
Zou, J.5
Dowey, S.6
Brodsky, R.A.7
Ohm, J.E.8
Yu, W.9
-
44
-
-
84855759349
-
Modulation of the pentose phosphate pathway induces endodermal differentiation in embryonic stem cells
-
Manganelli G, Fico A, Masullo U, Pizzolongo F, Cimmino A, Filosa S. 2012. Modulation of the pentose phosphate pathway induces endodermal differentiation in embryonic stem cells. PLoS One 7: e29321.
-
(2012)
Plos One
, vol.7
-
-
Manganelli, G.1
Fico, A.2
Masullo, U.3
Pizzolongo, F.4
Cimmino, A.5
Filosa, S.6
-
45
-
-
84938267949
-
An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate
-
Maryanovich M, Zaltsman Y, Ruggiero A, Goldman A, Shachnai L, Zaidman SL, Porat Z, Golan K, Lapidot T, Gross A. 2015. An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate. Nat Commun 6: 7901.
-
(2015)
Nat Commun
, vol.6
, pp. 7901
-
-
Maryanovich, M.1
Zaltsman, Y.2
Ruggiero, A.3
Goldman, A.4
Shachnai, L.5
Zaidman, S.L.6
Porat, Z.7
Golan, K.8
Lapidot, T.9
Gross, A.10
-
46
-
-
34249882777
-
Foxo3a is essential for maintenance of the hematopoietic stem cell pool
-
Miyamoto K, Araki KY, Naka K, Arai F, Takubo K, Yamazaki S, Matsuoka S, Miyamoto T, Ito K, Ohmura M, et al. 2007. Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell 1: 101–112.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 101-112
-
-
Miyamoto, K.1
Araki, K.Y.2
Naka, K.3
Arai, F.4
Takubo, K.5
Yamazaki, S.6
Matsuoka, S.7
Miyamoto, T.8
Ito, K.9
Ohmura, M.10
-
47
-
-
84924369505
-
Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells
-
Moussaieff A, Rouleau M, Kitsberg D, Cohen M, Levy G, Barasch D, Nemirovski A, Shen-Orr S, Laevsky I, Amit M, et al. 2015. Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells. Cell Metab 21: 392–402.
-
(2015)
Cell Metab
, vol.21
, pp. 392-402
-
-
Moussaieff, A.1
Rouleau, M.2
Kitsberg, D.3
Cohen, M.4
Levy, G.5
Barasch, D.6
Nemirovski, A.7
Shen-Orr, S.8
Laevsky, I.9
Amit, M.10
-
48
-
-
78649811793
-
Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells
-
Nakada D, Saunders TL, Morrison SJ. 2010. Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells. Nature 468: 653–658.
-
(2010)
Nature
, vol.468
, pp. 653-658
-
-
Nakada, D.1
Saunders, T.L.2
Morrison, S.J.3
-
49
-
-
33645090940
-
Inhibition of germline proliferation during C. Elegans dauer development requires PTEN, LKB1 and AMPK signalling
-
Narbonne P, Roy R. 2006. Inhibition of germline proliferation during C. elegans dauer development requires PTEN, LKB1 and AMPK signalling. Development 133: 611–619.
-
(2006)
Development
, vol.133
, pp. 611-619
-
-
Narbonne, P.1
Roy, R.2
-
50
-
-
84939248341
-
Differentiation of human neural stem cells into motor neurons stimulates mitochondrial biogenesis and decreases glycolytic flux
-
O’Brien LC, Keeney PM, Bennett JP Jr. 2015. Differentiation of human neural stem cells into motor neurons stimulates mitochondrial biogenesis and decreases glycolytic flux. Stem Cells Dev 24: 1984–1994.
-
(2015)
Stem Cells Dev
, vol.24
, pp. 1984-1994
-
-
O’Brien, L.C.1
Keeney, P.M.2
Bennett, J.P.3
-
51
-
-
70349446465
-
Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation
-
Owusu-Ansah E, Banerjee U. 2009. Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation. Nature 461: 537–541.
-
(2009)
Nature
, vol.461
, pp. 537-541
-
-
Owusu-Ansah, E.1
Banerjee, U.2
-
52
-
-
84871040682
-
Continuous and uninterrupted oxygen tension influences the colony formation and oxidative metabolism of human mesenchymal stem cells
-
Pattappa G, Thorpe SD, Jegard NC, Heywood HK, de Bruijn JD, Lee DA. 2013. Continuous and uninterrupted oxygen tension influences the colony formation and oxidative metabolism of human mesenchymal stem cells. Tissue Eng Part C Methods 19: 68–79.
-
(2013)
Tissue Eng Part C Methods
, vol.19
, pp. 68-79
-
-
Pattappa, G.1
Thorpe, S.D.2
Jegard, N.C.3
Heywood, H.K.4
De Bruijn, J.D.5
Lee, D.A.6
-
53
-
-
84962920513
-
Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming
-
Prieto J, León XP, Sendra R, Bort R, Ferrer-Lorente R, Raya A, López-García C, Torres J. 2016. Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming. Nat Commun 7: 11124.
-
(2016)
Nat Commun
, vol.7
-
-
Prieto, J.1
León, X.P.2
Sendra, R.3
Bort, R.4
Ferrer-Lorente, R.5
Raya, A.6
López-García, C.7
Torres, J.8
-
54
-
-
76049099052
-
Direct control of mitochondrial function by mTOR
-
Ramanathan A, Schreiber SL. 2009. Direct control of mitochondrial function by mTOR. Proc Natl Acad Sci 106: 22229–22232.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 22229-22232
-
-
Ramanathan, A.1
Schreiber, S.L.2
-
55
-
-
70350506802
-
FoxO3 regulates neural stem cell homeostasis
-
Renault VM, Rafalski VA, Morgan AA, Salih DA, Brett JO, Webb AE, Villeda SA, Thekkat PU, Guillerey C, Denko NC, et al. 2009. FoxO3 regulates neural stem cell homeostasis. Cell Stem Cell 5: 527–539.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 527-539
-
-
Renault, V.M.1
Rafalski, V.A.2
Morgan, A.A.3
Salih, D.A.4
Brett, J.O.5
Webb, A.E.6
Villeda, S.A.7
Thekkat, P.U.8
Guillerey, C.9
Denko, N.C.10
-
56
-
-
80455143200
-
Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog
-
Rera M, Bahadorani S, Cho J, Koehler CL, Ulgherait M, Hur JH, Ansari WS, Lo T Jr, Jones DL, Walker DW. 2011. Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog. Cell Metab 14: 623–634.
-
(2011)
Cell Metab
, vol.14
, pp. 623-634
-
-
Rera, M.1
Bahadorani, S.2
Cho, J.3
Koehler, C.L.4
Ulgherait, M.5
Hur, J.H.6
Ansari, W.S.7
Lo, T.8
Jones, D.L.9
Walker, D.W.10
-
57
-
-
84940797231
-
Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3
-
Rimmelé P, Liang R, Bigarella CL, Kocabas F, Xie J, Serasinghe MN, Chipuk J, Sadek H, Zhang CC, Ghaffari S. 2015. Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3. EMBO Rep 16: 1164–1176.
-
(2015)
EMBO Rep
, vol.16
, pp. 1164-1176
-
-
Rimmelé, P.1
Liang, R.2
Bigarella, C.L.3
Kocabas, F.4
Xie, J.5
Serasinghe, M.N.6
Chipuk, J.7
Sadek, H.8
Zhang, C.C.9
Ghaffari, S.10
-
58
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. 2005. Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1. Nature 434: 113–118.
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
59
-
-
39149086121
-
Stems cells and the pathways to aging and cancer
-
Rossi DJ, Jamieson CH, Weissman IL. 2008. Stems cells and the pathways to aging and cancer. Cell 132: 681–696.
-
(2008)
Cell
, vol.132
, pp. 681-696
-
-
Rossi, D.J.1
Jamieson, C.H.2
Weissman, I.L.3
-
60
-
-
84924857323
-
+-dependent SIRT deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells
-
+-dependent SIRT deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells. Cell Stem Cell 16: 171–183.
-
(2015)
Cell Stem Cell
, vol.16
, pp. 171-183
-
-
Ryall, J.G.1
Dell’Orso, S.2
Derfoul, A.3
Juan, A.4
Zare, H.5
Feng, X.6
Clermont, D.7
Koulnis, M.8
Gutierrez-Cruz, G.9
Fulco, M.10
-
61
-
-
33748752151
-
The mammalian target of rapamycin (MTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity
-
Schieke SM, Phillips D, McCoy JP Jr, Aponte AM, Shen RF, Balaban RS, Finkel T. 2006. The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity. J Biol Chem 281: 27643–27652.
-
(2006)
J Biol Chem
, vol.281
, pp. 27643-27652
-
-
Schieke, S.M.1
Phillips, D.2
McCoy, J.P.3
Aponte, A.M.4
Shen, R.F.5
Balaban, R.S.6
Finkel, T.7
-
62
-
-
84929273586
-
Mitochondrial alterations by PARKIN in dopaminergic neurons using PARK2 patient-specific and PARK2 knockout isogenic iPSC lines
-
Shaltouki A, Sivapatham R, Pei Y, Gerencser AA, Momcǐlovic O, Rao MS, Zeng X. 2015. Mitochondrial alterations by PARKIN in dopaminergic neurons using PARK2 patient-specific and PARK2 knockout isogenic iPSC lines. Stem Cell Rep 4: 847–859.
-
(2015)
Stem Cell Rep
, vol.4
, pp. 847-859
-
-
Shaltouki, A.1
Sivapatham, R.2
Pei, Y.3
Gerencser, A.A.4
Momcǐlovic, O.5
Rao, M.S.6
Zeng, X.7
-
63
-
-
84859429092
-
Direct sensing of systemic and nutritional signals by haematopoietic progenitors in Drosophila
-
Shim J, Mukherjee T, Banerjee U. 2012. Direct sensing of systemic and nutritional signals by haematopoietic progenitors in Drosophila. Nat Cell Biol 14: 394–400.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 394-400
-
-
Shim, J.1
Mukherjee, T.2
Banerjee, U.3
-
64
-
-
84900332195
-
Methionine metabolism regulates maintenance and differentiation of human pluripotent stem cells
-
Shiraki N, Shiraki Y, Tsuyama T, Obata F, Miura M, Nagae G, Aburatani H, Kume K, Endo F, Kume S. 2014. Methionine metabolism regulates maintenance and differentiation of human pluripotent stem cells. Cell Metab 19: 780–794.
-
(2014)
Cell Metab
, vol.19
, pp. 780-794
-
-
Shiraki, N.1
Shiraki, Y.2
Tsuyama, T.3
Obata, F.4
Miura, M.5
Nagae, G.6
Aburatani, H.7
Kume, K.8
Endo, F.9
Kume, S.10
-
65
-
-
84924350833
-
Metabolic switches linked to pluripotency and embryonic stem cell differentiation
-
Shyh-Chang N, Daley GQ. 2015. Metabolic switches linked to pluripotency and embryonic stem cell differentiation. Cell Metab 21: 349–350.
-
(2015)
Cell Metab
, vol.21
, pp. 349-350
-
-
Shyh-Chang, N.1
Daley, G.Q.2
-
66
-
-
84872160110
-
Influence of threonine metabolism on Sadenosylmethionine and histone methylation
-
Shyh-Chang N, Locasale JW, Lyssiotis CA, Zheng Y, Teo RY, Ratanasirintrawoot S, Zhang J, Onder T, Unternaehrer JJ, Zhu H, et al. 2013. Influence of threonine metabolism on Sadenosylmethionine and histone methylation. Science 339: 222–226.
-
(2013)
Science
, vol.339
, pp. 222-226
-
-
Shyh-Chang, N.1
Locasale, J.W.2
Lyssiotis, C.A.3
Zheng, Y.4
Teo, R.Y.5
Ratanasirintrawoot, S.6
Zhang, J.7
Onder, T.8
Unternaehrer, J.J.9
Zhu, H.10
-
67
-
-
77956205122
-
The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche
-
Simsek T, Kocabas F, Zheng J, Deberardinis RJ, Mahmoud AI, Olson EN, Schneider JW, Zhang CC, Sadek HA. 2010. The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. Cell Stem Cell 7: 380–390.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 380-390
-
-
Simsek, T.1
Kocabas, F.2
Zheng, J.3
Deberardinis, R.J.4
Mahmoud, A.I.5
Olson, E.N.6
Schneider, J.W.7
Zhang, C.C.8
Sadek, H.A.9
-
68
-
-
84900342698
-
Direct measurement of local oxygen concentration in the bone marrow of live animals
-
Spencer JA, Ferraro F, Roussakis E, Klein A, Wu J, Runnels JM, Zaher W, Mortensen LJ, Alt C, Turcotte R, et al. 2014. Direct measurement of local oxygen concentration in the bone marrow of live animals. Nature 508: 269–273.
-
(2014)
Nature
, vol.508
, pp. 269-273
-
-
Spencer, J.A.1
Ferraro, F.2
Roussakis, E.3
Klein, A.4
Wu, J.5
Runnels, J.M.6
Zaher, W.7
Mortensen, L.J.8
Alt, C.9
Turcotte, R.10
-
69
-
-
84948669098
-
The metabolome regulates the epigenetic landscape during naive-toprimed human embryonic stem cell transition
-
Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, Fischer KA, Devi A, Detraux D, Gu H, et al. 2015. The metabolome regulates the epigenetic landscape during naive-toprimed human embryonic stem cell transition. Nat Cell Biol 17: 1523–1535.
-
(2015)
Nat Cell Biol
, vol.17
, pp. 1523-1535
-
-
Sperber, H.1
Mathieu, J.2
Wang, Y.3
Ferreccio, A.4
Hesson, J.5
Xu, Z.6
Fischer, K.A.7
Devi, A.8
Detraux, D.9
Gu, H.10
-
70
-
-
84941711126
-
Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration
-
Stevens DA, Lee Y, Kang HC, Lee BD, Lee YI, Bower A, Jiang H, Kang SU, Andrabi SA, Dawson VL, et al. 2015. Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration. Proc Natl Acad Sci 112: 11696–11701.
-
(2015)
Proc Natl Acad Sci
, vol.112
, pp. 11696-11701
-
-
Stevens, D.A.1
Lee, Y.2
Kang, H.C.3
Lee, B.D.4
Lee, Y.I.5
Bower, A.6
Jiang, H.7
Kang, S.U.8
Andrabi, S.A.9
Dawson, V.L.10
-
71
-
-
84931339337
-
Neural stem cells in the adult subventricular zone oxidize fatty acids to produce energy and support neurogenic activity
-
Stoll EA, Makin R, Sweet IR, Trevelyan AJ, Miwa S, Horner PJ, Turnbull DM. 2015. Neural stem cells in the adult subventricular zone oxidize fatty acids to produce energy and support neurogenic activity. Stem Cells 33: 2306–2319.
-
(2015)
Stem Cells
, vol.33
, pp. 2306-2319
-
-
Stoll, E.A.1
Makin, R.2
Sweet, I.R.3
Trevelyan, A.J.4
Miwa, S.5
Horner, P.J.6
Turnbull, D.M.7
-
72
-
-
80053916176
-
Metabolic regulation of hematopoietic stem cells in the hypoxic niche
-
Suda T, Takubo K, Semenza GL. 2011. Metabolic regulation of hematopoietic stem cells in the hypoxic niche. Cell Stem Cell 9: 298–310.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 298-310
-
-
Suda, T.1
Takubo, K.2
Semenza, G.L.3
-
73
-
-
84908074395
-
Resetting transcription factor control circuitry toward ground-state pluripotency in human
-
Takashima Y, Guo G, Loos R, Nichols J, Ficz G, Krueger F, Oxley D, Santos F, Clarke J, Mansfield W, et al. 2014. Resetting transcription factor control circuitry toward ground-state pluripotency in human. Cell 158: 1254–1269.
-
(2014)
Cell
, vol.158
, pp. 1254-1269
-
-
Takashima, Y.1
Guo, G.2
Loos, R.3
Nichols, J.4
Ficz, G.5
Krueger, F.6
Oxley, D.7
Santos, F.8
Clarke, J.9
Mansfield, W.10
-
74
-
-
84872011926
-
Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells
-
Takubo K, Nagamatsu G, Kobayashi CI, Nakamura-Ishizu A, Kobayashi H, Ikeda E, Goda N, Rahimi Y, Johnson RS, Soga T, et al. 2013. Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells. Cell Stem Cell 12: 49–61.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 49-61
-
-
Takubo, K.1
Nagamatsu, G.2
Kobayashi, C.I.3
Nakamura-Ishizu, A.4
Kobayashi, H.5
Ikeda, E.6
Goda, N.7
Rahimi, Y.8
Johnson, R.S.9
Soga, T.10
-
75
-
-
84962467364
-
Stress from nucleotide depletion activates the transcriptional regulator HEXIM1 to suppress melanoma
-
Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, et al. 2016. Stress from nucleotide depletion activates the transcriptional regulator HEXIM1 to suppress melanoma. Mol Cell 62: 34–46.
-
(2016)
Mol Cell
, vol.62
, pp. 34-46
-
-
Tan, J.L.1
Fogley, R.D.2
Flynn, R.A.3
Ablain, J.4
Yang, S.5
Saint-André, V.6
Fan, Z.P.7
Do, B.T.8
Laga, A.C.9
Fujinaga, K.10
-
76
-
-
84979742769
-
α-Ketoglutarate accelerates the initial differentiation of primed human pluripotent stem cells
-
TeSlaa T, Chaikovsky AC, Lipchina I, Escobar SL, Hochedlinger K, Huang J, Graeber TG, Braas D, Teitell MA. 2016. α-Ketoglutarate accelerates the initial differentiation of primed human pluripotent stem cells. Cell Metab 24: 485–493.
-
(2016)
Cell Metab
, vol.24
, pp. 485-493
-
-
Teslaa, T.1
Chaikovsky, A.C.2
Lipchina, I.3
Escobar, S.L.4
Hochedlinger, K.5
Huang, J.6
Graeber, T.G.7
Braas, D.8
Teitell, M.A.9
-
77
-
-
33846419112
-
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
-
Tothova Z, Kollipara R, Huntly BJ, Lee BH, Castrillon DH, Cullen DE, McDowell EP, Lazo-Kallanian S, Williams IR, Sears C, et al. 2007. FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell 128: 325–339.
-
(2007)
Cell
, vol.128
, pp. 325-339
-
-
Tothova, Z.1
Kollipara, R.2
Huntly, B.J.3
Lee, B.H.4
Castrillon, D.H.5
Cullen, D.E.6
McDowell, E.P.7
Lazo-Kallanian, S.8
Williams, I.R.9
Sears, C.10
-
78
-
-
84930960191
-
Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2
-
Ueda T, Nagamachi A, Takubo K, Yamasaki N, Matsui H, Kanai A, Nakata Y, Ikeda K, Konuma T, Oda H, et al. 2015. Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2. Blood 125: 3437–3446.
-
(2015)
Blood
, vol.125
, pp. 3437-3446
-
-
Ueda, T.1
Nagamachi, A.2
Takubo, K.3
Yamasaki, N.4
Matsui, H.5
Kanai, A.6
Nakata, Y.7
Ikeda, K.8
Konuma, T.9
Oda, H.10
-
79
-
-
67650266694
-
Male germline stem cell division and spermatocyte growth require insulin signaling in Drosophila
-
Ueishi S, Shimizu H, H Inoue Y. 2009. Male germline stem cell division and spermatocyte growth require insulin signaling in Drosophila. Cell Struct Funct 34: 61–69.
-
(2009)
Cell Struct Funct
, vol.34
, pp. 61-69
-
-
Ueishi, S.1
Shimizu, H.2
H Inoue, Y.3
-
80
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
Vander Heiden MG, Cantley LC, Thompson CB. 2009. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324: 1029–1033.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
81
-
-
84991677482
-
Specification of haematopoietic stem cell fate via modulation of mitochondrial activity
-
Vannini N, Girotra M, Naveiras O, Nikitin G, Campos V, Giger S, Roch A, Auwerx J, Lutolf MP. 2016. Specification of haematopoietic stem cell fate via modulation of mitochondrial activity. Nat Commun 7: 13125.
-
(2016)
Nat Commun
, vol.7
-
-
Vannini, N.1
Girotra, M.2
Naveiras, O.3
Nikitin, G.4
Campos, V.5
Giger, S.6
Roch, A.7
Auwerx, J.8
Lutolf, M.P.9
-
82
-
-
79959221064
-
Energy metabolism in human pluripotent stem cells and their differentiated counterparts
-
Varum S, Rodrigues AS, Moura MB, Momcilovic O, Easley CA IV, Ramalho-Santos J, Van Houten B, Schatten G. 2011. Energy metabolism in human pluripotent stem cells and their differentiated counterparts. PLoS ONE 6: e20914.
-
(2011)
Plos ONE
, vol.6
-
-
Varum, S.1
Rodrigues, A.S.2
Moura, M.B.3
Momcilovic, O.4
Easley, C.I.5
Ramalho-Santos, J.6
Van Houten, B.7
Schatten, G.8
-
83
-
-
0242329881
-
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
-
Wakabayashi N, Itoh K, Wakabayashi J, Motohashi H, Noda S, Takahashi S, Imakado S, Kotsuji T, Otsuka F, Roop DR, et al. 2003. Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation. Nat Genet 35: 238–245.
-
(2003)
Nat Genet
, vol.35
, pp. 238-245
-
-
Wakabayashi, N.1
Itoh, K.2
Wakabayashi, J.3
Motohashi, H.4
Noda, S.5
Takahashi, S.6
Imakado, S.7
Kotsuji, T.8
Otsuka, F.9
Roop, D.R.10
-
84
-
-
67749140110
-
Dependence of mouse embryonic stem cells on threonine catabolism
-
Wang J, Alexander P, Wu L, Hammer R, Cleaver O, McKnight SL. 2009. Dependence of mouse embryonic stem cells on threonine catabolism. Science 325: 435–439.
-
(2009)
Science
, vol.325
, pp. 435-439
-
-
Wang, J.1
Alexander, P.2
Wu, L.3
Hammer, R.4
Cleaver, O.5
McKnight, S.L.6
-
85
-
-
84860309087
-
Drosophila follicle stem cells are regulated by proliferation and niche adhesion as well as mitochondria and ROS
-
Wang ZA, Huang J, Kalderon D. 2012. Drosophila follicle stem cells are regulated by proliferation and niche adhesion as well as mitochondria and ROS. Nat Commun 3: 769.
-
(2012)
Nat Commun
, vol.3
, pp. 769
-
-
Wang, Z.A.1
Huang, J.2
Kalderon, D.3
-
86
-
-
84896912846
-
Derivation of naive human embryonic stem cells
-
Ware CB, Nelson AM, Mecham B, et al. 2014. Derivation of naive human embryonic stem cells. Proc Natl Acad Sci 111: 4484–4489.
-
(2014)
Proc Natl Acad Sci
, vol.111
, pp. 4484-4489
-
-
Ware, C.B.1
Nelson, A.M.2
Mecham, B.3
-
87
-
-
84874192375
-
FOXO3A directs a protective autophagy program in haematopoietic stem cells
-
Warr MR, Binnewies M, Flach J, Reynaud D, Garg T, Malhotra R, Debnath J, Passegué E. 2013. FOXO3A directs a protective autophagy program in haematopoietic stem cells. Nature 494: 323–327.
-
(2013)
Nature
, vol.494
, pp. 323-327
-
-
Warr, M.R.1
Binnewies, M.2
Flach, J.3
Reynaud, D.4
Garg, T.5
Malhotra, R.6
Debnath, J.7
Passegué, E.8
-
88
-
-
84881610068
-
FOXO3 shares common targets with ASCL1 genome wide and inhibits ASCL1-dependent neurogenesis
-
Webb AE, Pollina EA, Vierbuchen T, Urbán N, Ucar D, Leeman DS, Martynoga B, Sewak M, Rando TA, Guillemot F, et al. 2013. FOXO3 shares common targets with ASCL1 genome wide and inhibits ASCL1-dependent neurogenesis. Cell Rep 4: 477–491.
-
(2013)
Cell Rep
, vol.4
, pp. 477-491
-
-
Webb, A.E.1
Pollina, E.A.2
Vierbuchen, T.3
Urbán, N.4
Ucar, D.5
Leeman, D.S.6
Martynoga, B.7
Sewak, M.8
Rando, T.A.9
Guillemot, F.10
-
89
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, Troy A, Cinti S, Lowell B, Scarpulla RC, et al. 1999. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 98: 115–124.
-
(1999)
Cell
, vol.98
, pp. 115-124
-
-
Wu, Z.1
Puigserver, P.2
Andersson, U.3
Zhang, C.4
Adelmant, G.5
Mootha, V.6
Troy, A.7
Cinti, S.8
Lowell, B.9
Scarpulla, R.C.10
-
90
-
-
84958026024
-
Inborn errors of long-chain fatty acid β-oxidation link neural stem cell self-renewal to autism
-
Xie Z, Jones A, Deeney JT, Hur SK, Bankaitis VA. 2016. Inborn errors of long-chain fatty acid β-oxidation link neural stem cell self-renewal to autism. Cell Rep 14: 991–999.
-
(2016)
Cell Rep
, vol.14
, pp. 991-999
-
-
Xie, Z.1
Jones, A.2
Deeney, J.T.3
Hur, S.K.4
Bankaitis, V.A.5
-
91
-
-
54449092731
-
Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells
-
Yalcin S, Zhang X, Luciano JP, Mungamuri SK, Marinkovic D, Vercherat C, Sarkar A, Grisotto M, Taneja R, Ghaffari S. 2008. Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells. J Biol Chem 283: 25692–25705.
-
(2008)
J Biol Chem
, vol.283
, pp. 25692-25705
-
-
Yalcin, S.1
Zhang, X.2
Luciano, J.P.3
Mungamuri, S.K.4
Marinkovic, D.5
Vercherat, C.6
Sarkar, A.7
Grisotto, M.8
Taneja, R.9
Ghaffari, S.10
-
93
-
-
77952545479
-
Meta bolic oxidation regulates embryonic stem cell differentiation
-
Yanes O, Clark J, Wong DM, Patti GJ, Sánchez-Ruiz A, Benton HP, Trauger SA, Desponts C, Ding S, Siuzdak G. 2010. Meta bolic oxidation regulates embryonic stem cell differentiation. Nat Chem Biol 6: 411–417.
-
(2010)
Nat Chem Biol
, vol.6
, pp. 411-417
-
-
Yanes, O.1
Clark, J.2
Wong, D.M.3
Patti, G.J.4
Sánchez-Ruiz, A.5
Benton, H.P.6
Trauger, S.A.7
Desponts, C.8
Ding, S.9
Siuzdak, G.10
-
94
-
-
44349170450
-
The ground state of embryonic stem cell self-renewal
-
Ying QL, Wray J, Nichols J, Batlle-Morera L, Doble B, Woodgett J, Cohen P, Smith A. 2008. The ground state of embryonic stem cell self-renewal. Nature 453: 519–523.
-
(2008)
Nature
, vol.453
, pp. 519-523
-
-
Ying, Q.L.1
Wray, J.2
Nichols, J.3
Batlle-Morera, L.4
Doble, B.5
Woodgett, J.6
Cohen, P.7
Smith, A.8
-
95
-
-
84856087055
-
Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis
-
Zhang WC, Shyh-Chang N, Yang H, Rai A, Umashankar S, Ma S, Soh BS, Sun LL, Tai BC, Nga ME, et al. 2012. Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis. Cell 148: 259–272.
-
(2012)
Cell
, vol.148
, pp. 259-272
-
-
Zhang, W.C.1
Shyh-Chang, N.2
Yang, H.3
Rai, A.4
Umashankar, S.5
Ma, S.6
Soh, B.S.7
Sun, L.L.8
Tai, B.C.9
Nga, M.E.10
-
96
-
-
84979734807
-
Distinct metabolic states can support self-renewal and lipogenesis in human pluripotent stem cells under different culture conditions
-
Zhang H, Badur MG, Divakaruni AS, Parker SJ, Jäger C, Hiller K, Murphy AN, Metallo CM. 2016. Distinct metabolic states can support self-renewal and lipogenesis in human pluripotent stem cells under different culture conditions. Cell Rep 16: 1536–1547.
-
(2016)
Cell Rep
, vol.16
, pp. 1536-1547
-
-
Zhang, H.1
Badur, M.G.2
Divakaruni, A.S.3
Parker, S.J.4
Jäger, C.5
Hiller, K.6
Murphy, A.N.7
Metallo, C.M.8
-
97
-
-
84860531487
-
HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition
-
Zhou W, Choi M, Margineantu D, Margaretha L, Hesson J, Cavanaugh C, Blau CA, Horwitz MS, Hockenbery D, Ware C, et al. 2012. HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition. EMBO J 31: 2103–2116.
-
(2012)
EMBO J
, vol.31
, pp. 2103-2116
-
-
Zhou, W.1
Choi, M.2
Margineantu, D.3
Margaretha, L.4
Hesson, J.5
Cavanaugh, C.6
Blau, C.A.7
Horwitz, M.S.8
Hockenbery, D.9
Ware, C.10
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