An elaborate regulation of mammalian target of rapamycin activity is required for somatic cell reprogramming induced by defined transcription factors

Stem Cells and Development

Volumn 21, Issue 14, 2012, Pages 2630-2641

  He, Jing ^a,b   Kang, Lan ^a   Wu, Tong ^a   Zhang, Jiqin ^c   Wang, Haitao ^a   Gao, Haibo ^a   Zhang, Yu ^a   Huang, Bo ^a   Liu, Wenqiang ^a   Kou, Zhaohui ^a   Zhang, Hongbing ^d   Gao, Shaorong ^a  

^a NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

^b BEIJING NORMAL UNIVERSITY   (China)

^c EAST CHINA NORMAL UNIVERSITY   (China)

^d INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; KRUPPEL LIKE FACTOR 4; MAMMALIAN TARGET OF RAPAMYCIN; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SOMATIC CELL;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; EMBRYO, MAMMALIAN; ENZYME ACTIVATION; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INDUCED PLURIPOTENT STEM CELLS; MALE; MICE; MICE, 129 STRAIN; OCTAMER TRANSCRIPTION FACTOR-3; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SIROLIMUS; SOXB1 TRANSCRIPTION FACTORS; SPECIFIC PATHOGEN-FREE ORGANISMS; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

IPS; MAMMALIA; MUS;

EID: 84866256464     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2012.0015     Document Type: Article

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