Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells

Nature

Volumn 532, Issue 7600, 2016, Pages 508-511

  Rentas, Stefan ^a   Holzapfel, Nicholas T ^a   Belew, Muluken S ^a   Pratt, Gabriel A ^b,c   Voisin, Veronique ^d   Wilhelm, Brian T ^e   Bader, Gary D ^d   Yeo, Gene W ^b,c,f   Hope, Kristin J ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

^e INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; MUSASHI 2 PROTEIN; RNA; RNA BINDING PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; AHR PROTEIN, HUMAN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; MESSENGER RNA; MSI2 PROTEIN, HUMAN; PROTEIN BINDING;

BLOOD; CELLS AND CELL COMPONENTS; GENE; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN ACTIVITY; HYDROCARBON; PROTEIN; RNA;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; EX VIVO STUDY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; STEM CELL; UMBILICAL CORD BLOOD; ANIMAL; CELL COUNT; CELL SELF-RENEWAL; CYTOLOGY; DOWN REGULATION; FEMALE; FETUS BLOOD; GENE SILENCING; GENETICS; MALE; METABOLISM; NUCLEOTIDE SEQUENCE; SIGNAL TRANSDUCTION;

ANIMALS; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL COUNT; CELL SELF RENEWAL; DOWN-REGULATION; FEMALE; FETAL BLOOD; GENE KNOCKDOWN TECHNIQUES; HEMATOPOIETIC STEM CELLS; HUMANS; MALE; MICE; PROTEIN BINDING; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION;

EID: 84964844342     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature17665     Document Type: Article

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