Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance

Science

Volumn 354, Issue 6316, 2016, Pages 1156-1160

  Ito, Kyoko ^a,b   Turcotte, Raphaël ^c   Cui, Jinhua ^a   Zimmerman, Samuel E ^a   Pinho, Sandra ^a   Mizoguchi, Toshihide ^a   Arai, Fumio ^d   Runnels, Judith M ^c   Alt, Clemens ^c   Teruya Feldstein, Julie ^e   Mar, Jessica C ^a   Singh, Rajat ^a   Suda, Toshio ^d,f   Lin, Charles P ^c   Frenette, Paul S ^a,b   Ito, Keisuke ^a,b  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b ALBERT EINSTEIN CANCER CENTER   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d KEIO UNIVERSITY   (Japan)

^e MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; FATTY ACID; GREEN FLUORESCENT PROTEIN; PARKIN; TEK PROTEIN, MOUSE; UBIQUITIN PROTEIN LIGASE;

CELLS AND CELL COMPONENTS; DIFFERENTIATION; HOMEOSTASIS; METABOLISM; MITOCHONDRION; QUALITY CONTROL;

ANIMAL CELL; ARTICLE; CELL POPULATION; CONTROLLED STUDY; FATTY ACID OXIDATION; HEMATOPOIETIC STEM CELL; METABOLISM; MITOCHONDRION; MITOPHAGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; STEM CELL SELF-RENEWAL; ANIMAL; C57BL MOUSE; CELL SELF-RENEWAL; CELL SEPARATION; CHEMISTRY; GENETICS; HEMATOPOIESIS; OXIDATION REDUCTION REACTION; PHYSIOLOGY; SINGLE CELL ANALYSIS;

MURINAE;

ANIMALS; CELL SELF RENEWAL; CELL SEPARATION; FATTY ACIDS; GREEN FLUORESCENT PROTEINS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; OXIDATION-REDUCTION; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; RECEPTOR, TIE-2; SINGLE-CELL ANALYSIS; UBIQUITIN-PROTEIN LIGASES;

EID: 84991108288     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaf5530     Document Type: Article

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