CRISPR-Cas9 Structures and Mechanisms

Annual Review of Biophysics

Volumn 46, Issue , 2017, Pages 505-529

  Jiang, Fuguo ^a,b   Doudna, Jennifer A ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

Cas9; CRISPR; Genome engineering; Mechanism; Off target; Structure

Indexed keywords

APOENZYME; CURVED DNA; DEOXYRIBONUCLEASE; GUIDE RNA; HETERODUPLEX; NUCLEASE; RNA; CRISPR ASSOCIATED PROTEIN; DNA;

CATALYSIS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; DNA BINDING; DNA CLEAVAGE; DNA DENATURATION; DNA STRAND; ENGINEERING; GENE TARGETING; GENETIC DISORDER; PRIORITY JOURNAL; REVIEW; CHEMISTRY; CRISPR CAS SYSTEM; GENETICS;

CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; DNA; RNA; RNA, GUIDE;

EID: 85019742802     PISSN: 1936122X     EISSN: 19361238     Source Type: Book Series    
DOI: 10.1146/annurev-biophys-062215-010822     Document Type: Review

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