Nucleosome breathing and remodeling constrain CRISPR-Cas9 function

eLife

Volumn 5, Issue APRIL2016, 2016, Pages

  Isaac, R Stefan ^a,b   Jiang, Fuguo ^c,d   Doudna, Jennifer A ^c,d,e   Lim, Wendell A ^b,d,f   Narlikar, Geeta J ^a   Almeida, Ricardo ^a,b,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^f HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREATHING; CHROMATIN ASSEMBLY AND DISASSEMBLY; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; DNA SEQUENCE; NUCLEOSOME; ANIMAL; CRISPR CAS SYSTEM; GENE EDITING; GENETIC RECOMBINATION; METABOLISM; PROCEDURES; XENOPUS;

BACTERIAL PROTEIN; CAS9 ENDONUCLEASE STREPTOCOCCUS PYOGENES; DNA; ENDONUCLEASE; NUCLEOSOME; PROTEIN BINDING;

ANIMALS; BACTERIAL PROTEINS; CRISPR-CAS SYSTEMS; DNA; ENDONUCLEASES; GENE EDITING; NUCLEOSOMES; PROTEIN BINDING; RECOMBINATION, GENETIC; XENOPUS;

EID: 84971539053     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.13450     Document Type: Article

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