메뉴 건너뛰기




Volumn 16, Issue 1, 2015, Pages

Genome editing: The end of the beginning

Author keywords

[No Author keywords available]

Indexed keywords

CRISPR ASSOCIATED PROTEIN; DNA; GREEN FLUORESCENT PROTEIN; SMALL INTERFERING RNA;

EID: 84951782881     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-015-0860-5     Document Type: Editorial
Times cited : (17)

References (37)
  • 1
    • 84913594397 scopus 로고    scopus 로고
    • Genome editing. The new frontier of genome engineering with CRISPR-Cas9
    • Doudna JA, Charpentier E. Genome editing. The new frontier of genome engineering with CRISPR-Cas9. Science. 2014;346(6213):1258096. doi: 10.1126/science.1258096.
    • (2014) Science , vol.346 , Issue.6213 , pp. 1258096
    • Doudna, J.A.1    Charpentier, E.2
  • 2
    • 84946558100 scopus 로고    scopus 로고
    • Diversity of CRISPR-Cas immune systems and molecular machines
    • Barrangou R. Diversity of CRISPR-Cas immune systems and molecular machines. Genome Biol. 2015;16:247. doi: 10.1186/s13059-015-0816-9.
    • (2015) Genome Biol , vol.16 , pp. 247
    • Barrangou, R.1
  • 3
    • 84895832944 scopus 로고    scopus 로고
    • Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
    • Fonfara I, Le Rhun A, Chylinski K, Makarova KS, Lecrivain AL, Bzdrenga J, et al. Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems. Nucleic Acids Res. 2014;42(4):2577-90. doi: 10.1093/nar/gkt1074.
    • (2014) Nucleic Acids Res , vol.42 , Issue.4 , pp. 2577-2590
    • Fonfara, I.1    Rhun, A.2    Chylinski, K.3    Makarova, K.S.4    Lecrivain, A.L.5    Bzdrenga, J.6
  • 4
    • 84887104139 scopus 로고    scopus 로고
    • Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
    • Esvelt KM, Mali P, Braff JL, Moosburner M, Yaung SJ, Church GM. Orthogonal Cas9 proteins for RNA-guided gene regulation and editing. Nat Methods. 2013;10(11):1116-21. doi: 10.1038/nmeth.2681.
    • (2013) Nat Methods , vol.10 , Issue.11 , pp. 1116-1121
    • Esvelt, K.M.1    Mali, P.2    Braff, J.L.3    Moosburner, M.4    Yaung, S.J.5    Church, G.M.6
  • 5
    • 84927514894 scopus 로고    scopus 로고
    • In vivo genome editing using Staphylococcus aureus Cas9
    • Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, et al. In vivo genome editing using Staphylococcus aureus Cas9. Nature. 2015;520(7546):186-91. doi: 10.1038/nature14299.
    • (2015) Nature , vol.520 , Issue.7546 , pp. 186-191
    • Ran, F.A.1    Cong, L.2    Yan, W.X.3    Scott, D.A.4    Gootenberg, J.S.5    Kriz, A.J.6
  • 7
    • 84947736727 scopus 로고    scopus 로고
    • Discovery and functional characterization of diverse class 2 CRISPR-Cas systems
    • Shmakov S, Abudayyeh OO, Makarova KS, Wolf YI, Gootenberg JS, Semenova E, et al. Discovery and functional characterization of diverse class 2 CRISPR-Cas systems. Mol Cell. 2015;60(3):385-97. doi: 10.1016/j.molcel.2015.10.008.
    • (2015) Mol Cell , vol.60 , Issue.3 , pp. 385-397
    • Shmakov, S.1    Abudayyeh, O.O.2    Makarova, K.S.3    Wolf, Y.I.4    Gootenberg, J.S.5    Semenova, E.6
  • 8
    • 84947730555 scopus 로고    scopus 로고
    • Rapid characterization of CRISPR-Cas9 protospacer adjacent motif sequence elements
    • Karvelis T, Gasiunas G, Young J, Bigelyte G, Silanskas A, Cigan M, et al. Rapid characterization of CRISPR-Cas9 protospacer adjacent motif sequence elements. Genome Biol. 2015;16:253. doi: 10.1186/s13059-015-0818-7.
    • (2015) Genome Biol , vol.16 , pp. 253
    • Karvelis, T.1    Gasiunas, G.2    Young, J.3    Bigelyte, G.4    Silanskas, A.5    Cigan, M.6
  • 9
    • 84946919064 scopus 로고    scopus 로고
    • Dynamics of CRISPR-Cas9 genome interrogation in living cells
    • Knight SC, Xie L, Deng W, Guglielmi B, Witkowsky LB, Bosanac L, et al. Dynamics of CRISPR-Cas9 genome interrogation in living cells. Science. 2015;350(6262):823-6. doi: 10.1126/science.aac6572.
    • (2015) Science , vol.350 , Issue.6262 , pp. 823-826
    • Knight, S.C.1    Xie, L.2    Deng, W.3    Guglielmi, B.4    Witkowsky, L.B.5    Bosanac, L.6
  • 10
    • 84946215320 scopus 로고    scopus 로고
    • Conformational control of DNA target cleavage by CRISPR-Cas9
    • Sternberg SH, LaFrance B, Kaplan M, Doudna JA. Conformational control of DNA target cleavage by CRISPR-Cas9. Nature. 2015;527(7576):110-3. doi: 10.1038/nature15544.
    • (2015) Nature , vol.527 , Issue.7576 , pp. 110-113
    • Sternberg, S.H.1    LaFrance, B.2    Kaplan, M.3    Doudna, J.A.4
  • 11
    • 84870766296 scopus 로고    scopus 로고
    • Repair of strand breaks by homologous recombination
    • Jasin M, Rothstein R. Repair of strand breaks by homologous recombination. Cold Spring Harb Perspect Biol. 2013;5(11):a012740. doi: 10.1101/cshperspect.a012740.
    • (2013) Cold Spring Harb Perspect Biol , vol.5 , Issue.11 , pp. a012740
    • Jasin, M.1    Rothstein, R.2
  • 12
    • 84955749431 scopus 로고    scopus 로고
    • Resources for the design of CRISPR gene editing experiments
    • Graham DB, Root DE. Resources for the design of CRISPR gene editing experiments. Genome Biol. 2015;16:260. doi: 10.1186/s13059-015-0823-x.
    • (2015) Genome Biol , vol.16 , pp. 260
    • Graham, D.B.1    Root, D.E.2
  • 13
    • 84945926658 scopus 로고    scopus 로고
    • WU-CRISPR: characteristics of functional guide RNAs for the CRISPR/Cas9 system
    • Wong N, Liu W, Wang X. WU-CRISPR: characteristics of functional guide RNAs for the CRISPR/Cas9 system. Genome Biol. 2015;16:218. doi: 10.1186/s13059-015-0784-0.
    • (2015) Genome Biol , vol.16 , pp. 218
    • Wong, N.1    Liu, W.2    Wang, X.3
  • 14
    • 84946567748 scopus 로고    scopus 로고
    • A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression
    • Xi L, Schmidt JC, Zaug AJ, Ascarrunz DR, Cech TR. A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression. Genome Biol. 2015;16:231. doi: 10.1186/s13059-015-0791-1.
    • (2015) Genome Biol , vol.16 , pp. 231
    • Xi, L.1    Schmidt, J.C.2    Zaug, A.J.3    Ascarrunz, D.R.4    Cech, T.R.5
  • 15
    • 84945567414 scopus 로고    scopus 로고
    • Network analysis of gene essentiality in functional genomics experiments
    • Jiang P, Wang H, Li W, Zang C, Li B, Wong YJ, et al. Network analysis of gene essentiality in functional genomics experiments. Genome Biol. 2015;16:239. doi: 10.1186/s13059-015-0808-9.
    • (2015) Genome Biol , vol.16 , pp. 239
    • Jiang, P.1    Wang, H.2    Li, W.3    Zang, C.4    Li, B.5    Wong, Y.J.6
  • 16
    • 84946919356 scopus 로고    scopus 로고
    • Zinc finger nuclease-based double-strand breaks attenuate malaria parasites and reveal rare microhomology-mediated end joining
    • Singer M, Marshall J, Heiss K, Mair GR, Grimm D, Mueller AK, et al. Zinc finger nuclease-based double-strand breaks attenuate malaria parasites and reveal rare microhomology-mediated end joining. Genome Biol. 2015;16:249. doi: 10.1186/s13059-015-0811-1.
    • (2015) Genome Biol , vol.16 , pp. 249
    • Singer, M.1    Marshall, J.2    Heiss, K.3    Mair, G.R.4    Grimm, D.5    Mueller, A.K.6
  • 17
    • 84946416320 scopus 로고    scopus 로고
    • High-frequency, precise modification of the tomato genome
    • Cermak T, Baltes NJ, Cegan R, Zhang Y, Voytas DF. High-frequency, precise modification of the tomato genome. Genome Biol. 2015;16:232. doi: 10.1186/s13059-015-0796-9.
    • (2015) Genome Biol , vol.16 , pp. 232
    • Cermak, T.1    Baltes, N.J.2    Cegan, R.3    Zhang, Y.4    Voytas, D.F.5
  • 18
    • 84937568562 scopus 로고    scopus 로고
    • Egg cell-specific promoter-controlled CRISPR/Cas9 efficiently generates homozygous mutants for multiple target genes in Arabidopsis in a single generation
    • Wang ZP, Xing HL, Dong L, Zhang HY, Han CY, Wang XC, et al. Egg cell-specific promoter-controlled CRISPR/Cas9 efficiently generates homozygous mutants for multiple target genes in Arabidopsis in a single generation. Genome Biol. 2015;16:144. doi: 10.1186/s13059-015-0715-0.
    • (2015) Genome Biol , vol.16 , pp. 144
    • Wang, Z.P.1    Xing, H.L.2    Dong, L.3    Zhang, H.Y.4    Han, C.Y.5    Wang, X.C.6
  • 20
    • 84948761978 scopus 로고    scopus 로고
    • Induction of targeted, heritable mutations in barley and Brassica oleracea using RNA-guided Cas9 nuclease
    • Lawrenson T, Shorinola O, Stacey N, Li C, Ostergaard L, Patron N, et al. Induction of targeted, heritable mutations in barley and Brassica oleracea using RNA-guided Cas9 nuclease. Genome Biol. 2015;16:258. doi: 10.1186/s13059-015-0826-7.
    • (2015) Genome Biol , vol.16 , pp. 258
    • Lawrenson, T.1    Shorinola, O.2    Stacey, N.3    Li, C.4    Ostergaard, L.5    Patron, N.6
  • 21
    • 84947255513 scopus 로고    scopus 로고
    • DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins
    • Woo JW, Kim J, Kwon SI, Corvalan C, Cho SW, Kim H, et al. DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins. Nat Biotechnol. 2015;33:1162-4. doi: 10.1038/nbt.3389.
    • (2015) Nat Biotechnol , vol.33 , pp. 1162-1164
    • Woo, J.W.1    Kim, J.2    Kwon, S.I.3    Corvalan, C.4    Cho, S.W.5    Kim, H.6
  • 22
    • 84921934205 scopus 로고    scopus 로고
    • Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew
    • Wang Y, Cheng X, Shan Q, Zhang Y, Liu J, Gao C, et al. Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew. Nat Biotechnol. 2014;32(9):947-51. doi: 10.1038/nbt.2969.
    • (2014) Nat Biotechnol , vol.32 , Issue.9 , pp. 947-951
    • Wang, Y.1    Cheng, X.2    Shan, Q.3    Zhang, Y.4    Liu, J.5    Gao, C.6
  • 23
    • 85042815594 scopus 로고    scopus 로고
    • Targeted genome modification of crop plants using a CRISPR-Cas system
    • Shan Q, Wang Y, Li J, Zhang Y, Chen K, Liang Z, et al. Targeted genome modification of crop plants using a CRISPR-Cas system. Nat Biotechnol. 2013;31(8):686-8. doi: 10.1038/nbt.2650.
    • (2013) Nat Biotechnol , vol.31 , Issue.8 , pp. 686-688
    • Shan, Q.1    Wang, Y.2    Li, J.3    Zhang, Y.4    Chen, K.5    Liang, Z.6
  • 24
    • 84883828590 scopus 로고    scopus 로고
    • Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease
    • Nekrasov V, Staskawicz B, Weigel D, Jones JD, Kamoun S. Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease. Nat Biotechnol. 2013;31(8):691-3. doi: 10.1038/nbt.2655.
    • (2013) Nat Biotechnol , vol.31 , Issue.8 , pp. 691-693
    • Nekrasov, V.1    Staskawicz, B.2    Weigel, D.3    Jones, J.D.4    Kamoun, S.5
  • 25
    • 84951813219 scopus 로고    scopus 로고
    • Towards a new era in medicine: therapeutic genome editing
    • Porteus MH. Towards a new era in medicine: therapeutic genome editing. Genome Biol. 2015;16:286.
    • (2015) Genome Biol , vol.16 , pp. 286
    • Porteus, M.H.1
  • 26
    • 84947714470 scopus 로고    scopus 로고
    • Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications
    • Friedland AE, Baral R, Singhal P, Loveluck K, Shen S, Sanchez M, et al. Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications. Genome Biol. 2015;16:257. doi: 10.1186/s13059-015-0817-8.
    • (2015) Genome Biol , vol.16 , pp. 257
    • Friedland, A.E.1    Baral, R.2    Singhal, P.3    Loveluck, K.4    Shen, S.5    Sanchez, M.6
  • 27
    • 84942912469 scopus 로고    scopus 로고
    • Enabling functional genomics with genome engineering
    • Hilton IB, Gersbach CA. Enabling functional genomics with genome engineering. Genome Res. 2015;25(10):1442-55. doi: 10.1101/gr.190124.115.
    • (2015) Genome Res , vol.25 , Issue.10 , pp. 1442-1455
    • Hilton, I.B.1    Gersbach, C.A.2
  • 28
    • 84890048526 scopus 로고    scopus 로고
    • Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins
    • Maeder ML, Angstman JF, Richardson ME, Linder SJ, Cascio VM, Tsai SQ, et al. Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins. Nat Biotechnol. 2013;31(12):1137-42. doi: 10.1038/nbt.2726.
    • (2013) Nat Biotechnol , vol.31 , Issue.12 , pp. 1137-1142
    • Maeder, M.L.1    Angstman, J.F.2    Richardson, M.E.3    Linder, S.J.4    Cascio, V.M.5    Tsai, S.Q.6
  • 29
    • 84886084801 scopus 로고    scopus 로고
    • Locus-specific editing of histone modifications at endogenous enhancers
    • Mendenhall EM, Williamson KE, Reyon D, Zou JY, Ram O, Joung JK, et al. Locus-specific editing of histone modifications at endogenous enhancers. Nat Biotechnol. 2013;31(12):1133-6. doi: 10.1038/nbt.2701.
    • (2013) Nat Biotechnol , vol.31 , Issue.12 , pp. 1133-1136
    • Mendenhall, E.M.1    Williamson, K.E.2    Reyon, D.3    Zou, J.Y.4    Ram, O.5    Joung, J.K.6
  • 30
    • 84882976110 scopus 로고    scopus 로고
    • Optical control of mammalian endogenous transcription and epigenetic states
    • Konermann S, Brigham MD, Trevino AE, Hsu PD, Heidenreich M, Cong L, et al. Optical control of mammalian endogenous transcription and epigenetic states. Nature. 2013;500(7463):472-6. doi: 10.1038/nature12466.
    • (2013) Nature , vol.500 , Issue.7463 , pp. 472-476
    • Konermann, S.1    Brigham, M.D.2    Trevino, A.E.3    Hsu, P.D.4    Heidenreich, M.5    Cong, L.6
  • 31
    • 84928924333 scopus 로고    scopus 로고
    • Functional annotation of native enhancers with a Cas9-histone demethylase fusion
    • Kearns NA, Pham H, Tabak B, Genga RM, Silverstein NJ, Garber M, et al. Functional annotation of native enhancers with a Cas9-histone demethylase fusion. Nat Methods. 2015;12(5):401-3. doi: 10.1038/nmeth.3325.
    • (2015) Nat Methods , vol.12 , Issue.5 , pp. 401-403
    • Kearns, N.A.1    Pham, H.2    Tabak, B.3    Genga, R.M.4    Silverstein, N.J.5    Garber, M.6
  • 32
    • 84929135130 scopus 로고    scopus 로고
    • Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
    • Hilton IB, D'Ippolito AM, Vockley CM, Thakore PI, Crawford GE, Reddy TE, et al. Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. Nat Biotechnol. 2015;33(5):510-7. doi: 10.1038/nbt.3199.
    • (2015) Nat Biotechnol , vol.33 , Issue.5 , pp. 510-517
    • Hilton, I.B.1    D'Ippolito, A.M.2    Vockley, C.M.3    Thakore, P.I.4    Crawford, G.E.5    Reddy, T.E.6
  • 33
    • 84947930919 scopus 로고    scopus 로고
    • P16-specific DNA methylation by engineered zinc finger methyltransferase inactivates gene transcription and promotes cancer metastasis
    • Cui C, Gan Y, Gu L, Wilson J, Liu Z, Zhang B, et al. P16-specific DNA methylation by engineered zinc finger methyltransferase inactivates gene transcription and promotes cancer metastasis. Genome Biol. 2015;16:252. doi: 10.1186/s13059-015-0819-6.
    • (2015) Genome Biol , vol.16 , pp. 252
    • Cui, C.1    Gan, Y.2    Gu, L.3    Wilson, J.4    Liu, Z.5    Zhang, B.6
  • 34
    • 84949100864 scopus 로고    scopus 로고
    • Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements
    • Thakore PI, D'Ippolito AM, Song L, Safi A, Shivakumar NK, Kabadi AM, et al. Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements. Nat Methods. 2015;12(12):1143-9. doi: 10.1038/nmeth.3630.
    • (2015) Nat Methods , vol.12 , Issue.12 , pp. 1143-1149
    • Thakore, P.I.1    D'Ippolito, A.M.2    Song, L.3    Safi, A.4    Shivakumar, N.K.5    Kabadi, A.M.6
  • 35
    • 84946716449 scopus 로고    scopus 로고
    • Mammoth 2.0: will genome engineering resurrect extinct species?
    • Shapiro B. Mammoth 2.0: will genome engineering resurrect extinct species? Genome Biol. 2015;16:228. doi: 10.1186/s13059-015-0800-4.
    • (2015) Genome Biol , vol.16 , pp. 228
    • Shapiro, B.1
  • 36
    • 84946402356 scopus 로고    scopus 로고
    • The societal opportunities and challenges of genome editing
    • Carroll D, Charo RA. The societal opportunities and challenges of genome editing. Genome Biol. 2015;16:242. doi: 10.1186/s13059-015-0812-0.
    • (2015) Genome Biol , vol.16 , pp. 242
    • Carroll, D.1    Charo, R.A.2
  • 37
    • 84947740923 scopus 로고    scopus 로고
    • Accelerating research through reagent repositories: the genome editing example
    • Joung JK, Voytas DF, Kamens J. Accelerating research through reagent repositories: the genome editing example. Genome Biol. 2015;16:255. doi: 10.1186/s13059-015-0830-y.
    • (2015) Genome Biol , vol.16 , pp. 255
    • Joung, J.K.1    Voytas, D.F.2    Kamens, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.