Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli

Nature

Volumn 530, Issue 7591, 2016, Pages 499-503

  Hayes, Robert P ^a   Xiao, Yibei ^a   Ding, Fran ^a   Van Erp, Paul B G ^c   Rajashankar, Kanagalaghatta ^a   Bailey, Scott ^b   Wiedenheft, Blake ^c   Ke, Ailong ^a  

^a Cornell University ^*  (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c MONTANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; BACTERIAL RNA; CASB PROTEIN, E COLI; CRISPR ASSOCIATED PROTEIN; CSE1 PROTEIN, E COLI; DNA; DNA HELICASE; ESCHERICHIA COLI PROTEIN; MULTIPROTEIN COMPLEX; PROTEIN SUBUNIT; YGCB PROTEIN, E COLI;

BACTERIUM; CELLS AND CELL COMPONENTS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; GENE EXPRESSION; IMMUNE SYSTEM; PROKARYOTE; PROTEIN; RECOGNITION;

ARTICLE; BASE PAIRING; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT COMPLEX FOR ANTIVIRAL DEFENCE TYPE I E; CONFORMATIONAL TRANSITION; CRISPR CAS SYSTEM; CRYSTAL STRUCTURE; DNA SEQUENCE; DNA STRAND; DNA STRUCTURE; ESCHERICHIA COLI; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTOSPACER ADJACENT MOTIF; STATIC ELECTRICITY; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE MOTIF; NUCLEOTIDE SEQUENCE; PROTEIN SUBUNIT; X RAY CRYSTALLOGRAPHY;

ESCHERICHIA COLI; PROKARYOTA;

BASE PAIRING; BASE SEQUENCE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-ASSOCIATED PROTEINS; CRYSTALLOGRAPHY, X-RAY; DNA; DNA HELICASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; NUCLEOTIDE MOTIFS; PROTEIN SUBUNITS; RNA, BACTERIAL;

EID: 84959422840     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature16995     Document Type: Article

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