Origins of Programmable Nucleases for Genome Engineering

Journal of Molecular Biology

Volumn 428, Issue 5, 2016, Pages 963-989

  Chandrasegaran, Srinivasan ^a   Carroll, Dana ^b  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

CRISPR Cas9; Gene therapy; Genome editing; Transcription activator like effector nucleases (TALENs); Zinc finger nucleases (ZFNs)

Indexed keywords

TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; ZINC FINGER NUCLEASE; DEOXYRIBONUCLEASE; RECOMBINANT PROTEIN; RIBONUCLEASE;

BINDING SITE; CRISPR CAS SYSTEM; DNA CLEAVAGE; DNA SEQUENCE; ENZYME ACTIVATION; ENZYME ENGINEERING; ENZYME METABOLISM; ENZYME SUBSTRATE; GENE LOCUS; GENOME; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; REVIEW; ANIMAL; CELL ENGINEERING; GENE TARGETING; GENETIC ENGINEERING; GENETIC RECOMBINATION; GENETICS; HUMAN; MAMMAL; METABOLISM; MOLECULAR MEDICINE; PLANT; PROCEDURES;

ANIMALS; CELL ENGINEERING; DEOXYRIBONUCLEASES; GENE TARGETING; GENETIC ENGINEERING; HUMANS; MAMMALS; MOLECULAR MEDICINE; PLANTS; RECOMBINANT PROTEINS; RECOMBINATION, GENETIC; RIBONUCLEASES;

EID: 84960832490     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2015.10.014     Document Type: Review

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