Therapeutic genome editing: Prospects and challenges

Nature Medicine

Volumn 21, Issue 2, 2015, Pages 121-131

  Cox, David Benjamin Turitz ^a,b,c   Platt, Randall Jeffrey ^a,b,c,d   Zhang, Feng ^a,b,c,d  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEASE; DEOXYRIBONUCLEASE;

CELL CYCLE REGULATION; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; COMPARATIVE STUDY; DNA END JOINING REPAIR; EUKARYOTIC CELL; GAIN OF FUNCTION MUTATION; GENE FUNCTION; GENE INSERTION; GENE PRODUCT; GENETIC PARAMETERS; GENOME EDITING; HUMAN; LOSS OF FUNCTION MUTATION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; THERAPY EFFECT; GENE THERAPY; GENETIC ENGINEERING; GENOME; TRENDS;

ANIMALIA; EUKARYOTA;

DEOXYRIBONUCLEASES; ENDODEOXYRIBONUCLEASES; GENETIC ENGINEERING; GENETIC THERAPY; GENOME; HUMANS;

EID: 84923106217     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3793     Document Type: Review

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