Cut site selection by the two nuclease domains of the Cas9 RNA-guided endonuclease

Journal of Biological Chemistry

Volumn 289, Issue 19, 2014, Pages 13284-13294

  Chen, Hongfan ^a   Choi, Jihoon ^a   Bailey, Scott ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SITE SELECTION;

CLEAVAGE SITES; DNA TARGETS; ENDONUCLEASES; MULTIPLE-MODELING; NUCLEASE DOMAIN; ORTHOLOGS; PALINDROMIC; STREPTOCOCCUS THERMOPHILUS;

RNA;

ENDONUCLEASE; PROTEIN CAS9; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DNA CLEAVAGE; ENZYME ACTIVATION; GENE TARGETING; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR CLONING; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN MOTIF; PROTOSPACER ADJACENT MOTIF; SEQUENCE ANALYSIS; STREPTOCOCCUS THERMOPHILUS;

CAS9; CRISPR; DNA; DNA TRANSFORMATION; DNA-BINDING PROTEIN; GENOME EDITING; NUCLEASE; RNA; RNA-BINDING PROTEIN;

BACTERIAL PROTEINS; DEOXYRIBONUCLEASE I; DNA, BACTERIAL; PROTEIN STRUCTURE, TERTIARY; RNA, BACTERIAL; STREPTOCOCCUS THERMOPHILUS;

EID: 84900395692     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.539726     Document Type: Article

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