Key proteins and pathways that regulate lifespan

Journal of Biological Chemistry

Volumn 292, Issue 16, 2017, Pages 6452-6460

  Pan, Haihui ^a   Finkel, Toren ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGY;

AGE-RELATED DISEASE; GROWTH FACTOR; LIFE SPAN; RATIONAL DESIGN; SIMPLE MODELING; SIRTUIN; SMALL MOLECULES; TARGET OF RAPAMYCIN;

PROTEINS;

GROWTH HORMONE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; NICOTINAMIDE RIBOSIDE; PROTEIN; RESVERATROL; SIRTUIN 1; SIRTUIN 2; SIRTUIN 6; SOMATOMEDIN; TRANSCRIPTION FACTOR FOXO; MTOR PROTEIN, HUMAN; SIRTUIN; SOMATOMEDIN C; TARGET OF RAPAMYCIN KINASE;

AGING; AUTOPHAGY; CALORIC RESTRICTION; CANCER INCIDENCE; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE RESISTANCE; GENE OVEREXPRESSION; HORMONE RELEASE; HUMAN; LIFE EXTENSION; LIFESPAN; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; SIR2 GENE; STRESS; SUPPLEMENTATION; ANIMAL; CAENORHABDITIS ELEGANS; GENE EXPRESSION REGULATION; LONGEVITY; MOUSE; PHOSPHORYLATION; PHYSIOLOGY;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; CALORIC RESTRICTION; GENE EXPRESSION REGULATION; HUMANS; INSULIN; INSULIN-LIKE GROWTH FACTOR I; LONGEVITY; MICE; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SIRTUINS; TOR SERINE-THREONINE KINASES;

EID: 85018606735     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.R116.771915     Document Type: Review

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