Germline Signaling Mediates the Synergistically Prolonged Longevity Produced by Double Mutations in daf-2 and rsks-1 in C.elegans

Cell Reports

Volumn 5, Issue 6, 2013, Pages 1600-1610

  Chen, Di ^a   Li, Patrick Wai Lun ^b   Goldstein, Benjamin A ^c   Cai, Waijiao ^d   Thomas, EmmaLynn ^b   Chen, Fen ^a   Hubbard, Alan E ^c   Melov, Simon ^b   Kapahi, Pankaj ^b  

^a NANJING UNIVERSITY   (China)

^b BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR DAF 16;

ANIMAL EXPERIMENT; ARTICLE; CAENORHABDITIS ELEGANS; CELL ACTIVATION; CONTROLLED STUDY; DAF 2 GENE; DEVELOPMENT; DIET RESTRICTION; GENE; GENE DELETION; GENE INTERACTION; GENE MUTATION; GERMLINE MICRONUCLEUS; HEAT STRESS; INTRACELLULAR SIGNALING; LIFE EXTENSION; LONGEVITY; LOSS OF FUNCTION MUTATION; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REPRODUCTION; RSKS 1 GENE; TISSUE SPECIFICITY;

CAENORHABDITIS ELEGANS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; FEEDBACK, PHYSIOLOGICAL; GERM CELLS; GERM-LINE MUTATION; INTESTINES; LONGEVITY; RECEPTOR, INSULIN; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84890973318     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2013.11.018     Document Type: Article

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