Somatotropic signaling: Trade-offs between growth, reproductive development, and longevity

Physiological Reviews

Volumn 93, Issue 2, 2013, Pages 571-598

  Bartke, Andrzej ^a,b,c   Sun, Liou Y ^a,b,c   Longo, Valter ^a,b,c  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DIQUAT; GROWTH HORMONE; GROWTH HORMONE RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PARAQUAT; PHOSPHATIDYLINOSITOL 3 KINASE; PITUITARY FACTOR 1; PRASTERONE SULFATE; PROLACTIN; PROTEIN; PROTEIN KINASE B; SOMATOMEDIN C; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

AGING; ARTICLE; BLOOD BRAIN BARRIER; BONE DENSITY; BRAIN ISCHEMIA; CARDIOVASCULAR DISEASE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLULAR STRESS RESPONSE; COGNITIVE DEFECT; DEPRESSION; DIABETES MELLITUS; DNA DAMAGE; ESTROGEN THERAPY; GENE EXPRESSION; GENE MUTATION; GENETIC VARIABILITY; GROWTH HORMONE DEFICIENCY; HETEROZYGOTE; HUMAN; INSULIN RESISTANCE; LIFE EXPECTANCY; LIFESPAN; LONGEVITY; LOSS OF FUNCTION MUTATION; METABOLIC SYNDROME X; NEOPLASM; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REPRODUCTION; RISK BENEFIT ANALYSIS; SEXUAL BEHAVIOR; SIGNAL TRANSDUCTION;

ANIMALS; GROWTH HORMONE; HUMANS; LONGEVITY; RECEPTORS, SOMATOTROPIN; REPRODUCTION; SIGNAL TRANSDUCTION;

EID: 84878473064     PISSN: 00319333     EISSN: 15221210     Source Type: Journal    
DOI: 10.1152/physrev.00006.2012     Document Type: Article

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