-
1
-
-
0020470466
-
Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes
-
Palmiter RD, Brinster RL, Hammer RE, Trumbauer ME, Rosenfeld MG, Brinberg NC, Evans RM: Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature 1982;611-615.
-
(1982)
Nature
, pp. 611-615
-
-
Palmiter, R.D.1
Brinster, R.L.2
Hammer, R.E.3
Trumbauer, M.E.4
Rosenfeld, M.G.5
Brinberg, N.C.6
Evans, R.M.7
-
2
-
-
0024336488
-
Glucocorticoid regulation of human growth hormone expression in transgenic mice and transiently transfected cells
-
Selden RF, Yun JS, Moore DD, Rowe ME, Malia MA, Wagner TE, Goodman HM: Glucocorticoid regulation of human growth hormone expression in transgenic mice and transiently transfected cells. J Endocrinol 1989;122:49-60.
-
(1989)
J Endocrinol
, vol.122
, pp. 49-60
-
-
Selden, R.F.1
Yun, J.S.2
Moore, D.D.3
Rowe, M.E.4
Malia, M.A.5
Wagner, T.E.6
Goodman, H.M.7
-
3
-
-
0023751235
-
Tissue-specific expression and dietary regulation of a chimeric phosphoenolpyruvate carboxykinase/bovine growth hormone gene in transgenic mice
-
McGrane MM, DeVente J, Yun JS, Bloom J, Park E, Wynshaw A, Wagner T, Rottman FM, Hanson RW: Tissue-specific expression and dietary regulation of a chimeric phosphoenolpyruvate carboxykinase/bovine growth hormone gene in transgenic mice. J Biol Chem 1988;263:11443-11451.
-
(1988)
J Biol Chem
, vol.263
, pp. 11443-11451
-
-
McGrane, M.M.1
DeVente, J.2
Yun, J.S.3
Bloom, J.4
Park, E.5
Wynshaw, A.6
Wagner, T.7
Rottman, F.M.8
Hanson, R.W.9
-
4
-
-
0021847770
-
Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth
-
Hammer RE, Brinster RL, Rosenfeld MG, Evans RM, Mayo KE: Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth. Nature 1985;315:413.
-
(1985)
Nature
, vol.315
, pp. 413
-
-
Hammer, R.E.1
Brinster, R.L.2
Rosenfeld, M.G.3
Evans, R.M.4
Mayo, K.E.5
-
5
-
-
0028291149
-
Dependence of increased linear bone growth on age at oMT1a-oGH transgene expression in mice
-
Oberbauer AM, Pomp D, Murray JD: Dependence of increased linear bone growth on age at oMT1a-oGH transgene expression in mice. Growth Dev Aging 1994;58:83-93.
-
(1994)
Growth Dev Aging
, vol.58
, pp. 83-93
-
-
Oberbauer, A.M.1
Pomp, D.2
Murray, J.D.3
-
6
-
-
0001414436
-
The ontogeny of resource allocation in giant transgenic rat growth hormone mice
-
Kajiura LJ, Rollo CD: The ontogeny of resource allocation in giant transgenic rat growth hormone mice. Can J Zool 1996;74:492-507.
-
(1996)
Can J Zool
, vol.74
, pp. 492-507
-
-
Kajiura, L.J.1
Rollo, C.D.2
-
7
-
-
0023553610
-
Growth allometry of the organs in giant transgenic mice
-
Shea BT, Hammer RE, Brinster RL: Growth allometry of the organs in giant transgenic mice. Endocrinology 1987;121:1924-1930.
-
(1987)
Endocrinology
, vol.121
, pp. 1924-1930
-
-
Shea, B.T.1
Hammer, R.E.2
Brinster, R.L.3
-
8
-
-
0023722908
-
Expression of the human growth hormone variant in cultured fibroblasts and transgenic mice
-
Selden RF, Wagner TE, Blethen S, Yun JS, Rowe ME, Goodman HM: Expression of the human growth hormone variant in cultured fibroblasts and transgenic mice. Proc Natl Acad Sci USA 1988;85:8241-8245.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 8241-8245
-
-
Selden, R.F.1
Wagner, T.E.2
Blethen, S.3
Yun, J.S.4
Rowe, M.E.5
Goodman, H.M.6
-
9
-
-
0027203976
-
Decrease in cellular replicative potential in 'giant' mice transfected with the bovine growth hormone gene correlates to shortened life span
-
Pendergrass WR, Li Y, Jiang D, Wolf NS: Decrease in cellular replicative potential in 'giant' mice transfected with the bovine growth hormone gene correlates to shortened life span. J Cell Physiol 1993;156:96-103.
-
(1993)
J Cell Physiol
, vol.156
, pp. 96-103
-
-
Pendergrass, W.R.1
Li, Y.2
Jiang, D.3
Wolf, N.S.4
-
10
-
-
0027178438
-
Effects of long-term elevated serum levels of growth hormone on life expectancy of mice: Lessons from transgenic animal models
-
Wolf E, Kahnt E, Ehrlein J, Hermanns W, Brem G, Wanke R: Effects of long-term elevated serum levels of growth hormone on life expectancy of mice: Lessons from transgenic animal models. Mech Ageing Dev 1993;68:71-87.
-
(1993)
Mech Ageing Dev
, vol.68
, pp. 71-87
-
-
Wolf, E.1
Kahnt, E.2
Ehrlein, J.3
Hermanns, W.4
Brem, G.5
Wanke, R.6
-
11
-
-
0000703708
-
Expression of human, but not bovine growth hormone genes promotes development of mammary tumors in transgenic mice
-
Cecim M, Bartke A, Yun JS, Wagner TE: Expression of human, but not bovine growth hormone genes promotes development of mammary tumors in transgenic mice. Transgenics 1994;1:431-437.
-
(1994)
Transgenics
, vol.1
, pp. 431-437
-
-
Cecim, M.1
Bartke, A.2
Yun, J.S.3
Wagner, T.E.4
-
12
-
-
0000887888
-
A mass budget for transgenic 'supermice' engineered with extra rat growth hormone genes: Evidence for energetic limitation
-
Kajiura LJ, Rollo CD: A mass budget for transgenic 'supermice' engineered with extra rat growth hormone genes: Evidence for energetic limitation. Can J Zool 1994;72:1010-1017.
-
(1994)
Can J Zool
, vol.72
, pp. 1010-1017
-
-
Kajiura, L.J.1
Rollo, C.D.2
-
13
-
-
0036553049
-
Consequences of growth hormone (GH) overexpression and GH resistance
-
Bartke A, Chandrashekar V, Bailey B, Zaczek D, Turyn D: Consequences of growth hormone (GH) overexpression and GH resistance. Neuropeptides 2002;36:201-208.
-
(2002)
Neuropeptides
, vol.36
, pp. 201-208
-
-
Bartke, A.1
Chandrashekar, V.2
Bailey, B.3
Zaczek, D.4
Turyn, D.5
-
14
-
-
0027345682
-
Premature ageing in transgenic mice expressing different growth hormone genes
-
Steger RW, Bartke A, Cecim M: Premature ageing in transgenic mice expressing different growth hormone genes. J Reprod Fertil Suppl 1993;46:61-75.
-
(1993)
J Reprod Fertil Suppl
, vol.46
, pp. 61-75
-
-
Steger, R.W.1
Bartke, A.2
Cecim, M.3
-
15
-
-
0029046938
-
Increased glial fibrillary acidic protein (GFAP) levels in the brains of transgenic mice expressing the bovine growth hormone (bGH) gene
-
Miller DB, Bartke A, O'Callaghan JP: Increased glial fibrillary acidic protein (GFAP) levels in the brains of transgenic mice expressing the bovine growth hormone (bGH) gene. Exp Gerontol 1995;30:383-400.
-
(1995)
Exp Gerontol
, vol.30
, pp. 383-400
-
-
Miller, D.B.1
Bartke, A.2
O'Callaghan, J.P.3
-
16
-
-
0024507405
-
Histopathology associated with elevated levels of growth hormone and insulin-like growth factor I in transgenic mice
-
Quaife CJ, Mathews LS, Pinkert CA, Hammer RE, Brinster RL, Palmiter RD: Histopathology associated with elevated levels of growth hormone and insulin-like growth factor I in transgenic mice. Endocrinology 1989;124:40-48.
-
(1989)
Endocrinology
, vol.124
, pp. 40-48
-
-
Quaife, C.J.1
Mathews, L.S.2
Pinkert, C.A.3
Hammer, R.E.4
Brinster, R.L.5
Palmiter, R.D.6
-
17
-
-
0020310068
-
The acromegaly syndrome
-
Jadresic A, Banks LM, Child DF, Diamant L, Doyle FH, Fraser TR, Joplin GF: The acromegaly syndrome. Q J Med 1982;202:189-204.
-
(1982)
Q J Med
, vol.202
, pp. 189-204
-
-
Jadresic, A.1
Banks, L.M.2
Child, D.F.3
Diamant, L.4
Doyle, F.H.5
Fraser, T.R.6
Joplin, G.F.7
-
20
-
-
0027357846
-
Aspects of the neuroendocrine control of growth hormone secretion in ageing mammals
-
Müller EE, Cella SG, De Gennaro Colonna V, Parenti M, Cocchi D, Locatelli V: Aspects of the neuroendocrine control of growth hormone secretion in ageing mammals. J Reprod Fertil Suppl 1993;46:99-114.
-
(1993)
J Reprod Fertil Suppl
, vol.46
, pp. 99-114
-
-
Müller, E.E.1
Cella, S.G.2
De Gennaro Colonna, V.3
Parenti, M.4
Cocchi, D.5
Locatelli, V.6
-
21
-
-
0022370713
-
Growth hormone, body composition, and aging
-
Rudman D: Growth hormone, body composition, and aging. J Am Geriatr Soc 1985;33:800-807.
-
(1985)
J Am Geriatr Soc
, vol.33
, pp. 800-807
-
-
Rudman, D.1
-
22
-
-
17544404567
-
Growth hormone: Hormone replacement for the somatopause?
-
Savine R, Sonksen P: Growth hormone: Hormone replacement for the somatopause? Horm Res 2000;53:37-41.
-
(2000)
Horm Res
, vol.53
, pp. 37-41
-
-
Savine, R.1
Sonksen, P.2
-
23
-
-
0025368959
-
Effects of human growth hormone in men over 60 years old
-
Rudman D, Feller AG, Nagraj HS, Gergans GA, Lalitha PY, Goldberg AF, Schlenker RA, Cohn L, Rudman IW, Mattson DE: Effects of human growth hormone in men over 60 years old. N Engl J Med 1990;323:1-6.
-
(1990)
N Engl J Med
, vol.323
, pp. 1-6
-
-
Rudman, D.1
Feller, A.G.2
Nagraj, H.S.3
Gergans, G.A.4
Lalitha, P.Y.5
Goldberg, A.F.6
Schlenker, R.A.7
Cohn, L.8
Rudman, I.W.9
Mattson, D.E.10
-
25
-
-
0034523517
-
The effects of growth hormone and IGF-I deficiency on cerebrovascular and brain ageing
-
Sonntag WE, Lynch C, Thornton P, Khan A, Bennett S, Ingram R: The effects of growth hormone and IGF-I deficiency on cerebrovascular and brain ageing. J Anat 2000;4:575-585.
-
(2000)
J Anat
, vol.4
, pp. 575-585
-
-
Sonntag, W.E.1
Lynch, C.2
Thornton, P.3
Khan, A.4
Bennett, S.5
Ingram, R.6
-
28
-
-
0035811073
-
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production
-
Flurkey K, Papaconstantinou J, Miller RA, Harrison DE: Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. Proc Natl Acad Sci USA 2001;98:6736-6741.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6736-6741
-
-
Flurkey, K.1
Papaconstantinou, J.2
Miller, R.A.3
Harrison, D.E.4
-
29
-
-
0347664057
-
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
-
Holzenberger M, Dupont J, Ducos B, Leneuve P, Geloen A, Even PC, Cervera P, LeBouc Y: IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 2003;421:182-187.
-
(2003)
Nature
, vol.421
, pp. 182-187
-
-
Holzenberger, M.1
Dupont, J.2
Ducos, B.3
Leneuve, P.4
Geloen, A.5
Even, P.C.6
Cervera, P.7
LeBouc, Y.8
-
30
-
-
0034966342
-
Evidence that Ames dwarf mice age differently from their normal siblings in behavioral and learning and memory parameters
-
Kinney BA, Meliska CJ, Steger RW, Bartke A: Evidence that Ames dwarf mice age differently from their normal siblings in behavioral and learning and memory parameters. Horm Behav 2001;39:277-284.
-
(2001)
Horm Behav
, vol.39
, pp. 277-284
-
-
Kinney, B.A.1
Meliska, C.J.2
Steger, R.W.3
Bartke, A.4
-
31
-
-
0035051811
-
Evidence that age-induced decline in memory retention is delayed in growth hormone resistant GH-R-KO (Laron) mice
-
Kinney BA, Coschigano KT, Kopchick JJ, Bartke A: Evidence that age-induced decline in memory retention is delayed in growth hormone resistant GH-R-KO (Laron) mice. Physiol Behav 2001;72:653-660.
-
(2001)
Physiol Behav
, vol.72
, pp. 653-660
-
-
Kinney, B.A.1
Coschigano, K.T.2
Kopchick, J.J.3
Bartke, A.4
-
32
-
-
0345237923
-
Delayed occurrence of fatal neoplastic diseases in Ames dwarf mice: Correlation to extended longevity
-
Ikeno Y, Bronson RT, Hubbard GB, Lee S, Bartke A: Delayed occurrence of fatal neoplastic diseases in Ames dwarf mice: Correlation to extended longevity. J Gerontol A Biol Sci Med Sci 2003;58:291-296.
-
(2003)
J Gerontol A Biol Sci Med Sci
, vol.58
, pp. 291-296
-
-
Ikeno, Y.1
Bronson, R.T.2
Hubbard, G.B.3
Lee, S.4
Bartke, A.5
-
33
-
-
0034626747
-
Genetic pathways that regulate ageing in model organisms
-
Guarente L, Kenyon C: Genetic pathways that regulate ageing in model organisms. Nature 2000;408:255-262.
-
(2000)
Nature
, vol.408
, pp. 255-262
-
-
Guarente, L.1
Kenyon, C.2
-
34
-
-
0037470501
-
The endocrine regulation of aging by insulin-like signals
-
Tatar M, Bartke A, Antebi A: The endocrine regulation of aging by insulin-like signals. Science 2003;299:1346-1351.
-
(2003)
Science
, vol.299
, pp. 1346-1351
-
-
Tatar, M.1
Bartke, A.2
Antebi, A.3
-
35
-
-
0036358167
-
Growth negatively impacts the life span of mammals
-
Rollo CD: Growth negatively impacts the life span of mammals. Evol Dev 2002;4:55-61.
-
(2002)
Evol Dev
, vol.4
, pp. 55-61
-
-
Rollo, C.D.1
-
36
-
-
0013056730
-
Big mice die young: Early life body weight predicts longevity in genetically heterogeneous mice
-
Miller RA, Harper JM, Galecki A, Burke DT: Big mice die young: Early life body weight predicts longevity in genetically heterogeneous mice. Aging Cell 2002;1:22-29.
-
(2002)
Aging Cell
, vol.1
, pp. 22-29
-
-
Miller, R.A.1
Harper, J.M.2
Galecki, A.3
Burke, D.T.4
-
37
-
-
0021075353
-
Metallothionein-human growth hormone fusion genes stimulate growth of mice
-
Palmiter RD, Norstedt G, Gelinas RE, Hammer RE, Brinster RL: Metallothionein-human growth hormone fusion genes stimulate growth of mice. Science 1983;222:809-814.
-
(1983)
Science
, vol.222
, pp. 809-814
-
-
Palmiter, R.D.1
Norstedt, G.2
Gelinas, R.E.3
Hammer, R.E.4
Brinster, R.L.5
-
38
-
-
0025037665
-
An immunocytochemical and ultrastructural study of adenohypophyses of mice transgenic for human growth hormone
-
Stefaneanu L, Kovacs K, Horvarth NE, Losinski E, Mayerhofer A, Wagner TE, Bartke A: An immunocytochemical and ultrastructural study of adenohypophyses of mice transgenic for human growth hormone. Endocrinology 1990;126:608-615.
-
(1990)
Endocrinology
, vol.126
, pp. 608-615
-
-
Stefaneanu, L.1
Kovacs, K.2
Horvarth, N.E.3
Losinski, E.4
Mayerhofer, A.5
Wagner, T.E.6
Bartke, A.7
-
39
-
-
0027332487
-
Effects of bovine growth hormone (GH) expression in transgenic mice on serum and pituitary immunoreactive mouse GH levels and pituitary GH-releasing factor binding sites
-
Copenh
-
Sotelo AI, Bartke A, Turyn D: Effects of bovine growth hormone (GH) expression in transgenic mice on serum and pituitary immunoreactive mouse GH levels and pituitary GH-releasing factor binding sites. Acta Endocrinol (Copenh) 1993;129:446-452.
-
(1993)
Acta Endocrinol
, vol.129
, pp. 446-452
-
-
Sotelo, A.I.1
Bartke, A.2
Turyn, D.3
-
40
-
-
0027959304
-
Neuroendocrine and reproductive consequences of overexpression of growth hormone in transgenic mice
-
Bartke A, Cecim M, Tang K, Steger RW, Chandrashekar V, Turyn D: Neuroendocrine and reproductive consequences of overexpression of growth hormone in transgenic mice. Proc Soc Exp Biol Med 1994;206:345-359.
-
(1994)
Proc Soc Exp Biol Med
, vol.206
, pp. 345-359
-
-
Bartke, A.1
Cecim, M.2
Tang, K.3
Steger, R.W.4
Chandrashekar, V.5
Turyn, D.6
-
41
-
-
0242690202
-
Effects of overexpression of different growth hormone genes on male reproductive functions in transgenic mice
-
Kula K, Slowikowska-Hilczer J (eds). Cracow, Polish Andrology Society and International Society of Andrology
-
Bartke A, Meliska C, Milton S, Johnson L, Chandrashekar V, Steger RW, Kopchick JJ: Effects of overexpression of different growth hormone genes on male reproductive functions in transgenic mice; in Kula K, Slowikowska-Hilczer J (eds): Hormonal Control of Spermatogenesis: Basic and Clinical Aspects. Cracow, Polish Andrology Society and International Society of Andrology, 1997, pp 1-15.
-
(1997)
Hormonal Control of Spermatogenesis: Basic and Clinical Aspects
, pp. 1-15
-
-
Bartke, A.1
Meliska, C.2
Milton, S.3
Johnson, L.4
Chandrashekar, V.5
Steger, R.W.6
Kopchick, J.J.7
-
42
-
-
0033501098
-
The growth hormone axis, feeding, and central allocative regulation: Lessons from giant transgenic growth hormone mice
-
Rollo CD, Kajiura LJ, Wylie B, D'Souza S: The growth hormone axis, feeding, and central allocative regulation: Lessons from giant transgenic growth hormone mice. Can J Zool 1999;77:1861-1873.
-
(1999)
Can J Zool
, vol.77
, pp. 1861-1873
-
-
Rollo, C.D.1
Kajiura, L.J.2
Wylie, B.3
D'Souza, S.4
-
43
-
-
0001858253
-
Growth allometry of transgenic mice expressing the mouse metallothionein-I/bovine growth hormone gene
-
Cecim M, Bartke A, Yun JS, Wagner TE: Growth allometry of transgenic mice expressing the mouse metallothionein-I/bovine growth hormone gene. Transgene 1993;1:125-132.
-
(1993)
Transgene
, vol.1
, pp. 125-132
-
-
Cecim, M.1
Bartke, A.2
Yun, J.S.3
Wagner, T.E.4
-
44
-
-
0001600049
-
Evidence for a trade-off between growth and behavioural activity in giant 'Supermice' genetically engineered with extra growth hormone genes
-
Lachmansingh E, Rollo CD: Evidence for a trade-off between growth and behavioural activity in giant 'Supermice' genetically engineered with extra growth hormone genes. Can J Zool 1994;72:2158-2168.
-
(1994)
Can J Zool
, vol.72
, pp. 2158-2168
-
-
Lachmansingh, E.1
Rollo, C.D.2
-
45
-
-
0028007708
-
Overexpression of growth hormone genes in transgenic mice shortens free-running periods in constant light
-
Ferraro JS, Dorsett JA, Wagner TE, Yun JS, Bartke A: Overexpression of growth hormone genes in transgenic mice shortens free-running periods in constant light. Biol Rhythms Res 1994;25:315-328.
-
(1994)
Biol Rhythms Res
, vol.25
, pp. 315-328
-
-
Ferraro, J.S.1
Dorsett, J.A.2
Wagner, T.E.3
Yun, J.S.4
Bartke, A.5
-
46
-
-
0026016354
-
Elevated corticosterone levels in transgenic mice expressing human or bovine growth hormone genes
-
Cecim M, Ghosh PK, Esquifino AI, Began T, Wagner TE, Yun JS, Bartke A: Elevated corticosterone levels in transgenic mice expressing human or bovine growth hormone genes. Neuroendocrinology 1991;53:313-316.
-
(1991)
Neuroendocrinology
, vol.53
, pp. 313-316
-
-
Cecim, M.1
Ghosh, P.K.2
Esquifino, A.I.3
Began, T.4
Wagner, T.E.5
Yun, J.S.6
Bartke, A.7
-
47
-
-
0030136639
-
Increased plasma corticosterone levels in bovine growth hormone (bGH) transgenic mice: Effects of ACTH, GH and IGF-I on in vitro adrenal corticosterone production
-
Cecim M, Alvarez-Sanz M, Van de Kar L, Milton S, Bartke A: Increased plasma corticosterone levels in bovine growth hormone (bGH) transgenic mice: Effects of ACTH, GH and IGF-I on in vitro adrenal corticosterone production. Transgenic Res 1996;5:187-192.
-
(1996)
Transgenic Res
, vol.5
, pp. 187-192
-
-
Cecim, M.1
Alvarez-Sanz, M.2
Van De Kar, L.3
Milton, S.4
Bartke, A.5
-
48
-
-
0023735288
-
Infertility in transgenic female mice with human growth hormone expression: Evidence for luteal failure
-
Bartke A, Steger RW, Hodges SL, Parkening TA, Collins TJ, Yun JS, Wagner TE: Infertility in transgenic female mice with human growth hormone expression: Evidence for luteal failure. J Exp Zool 1988;248:121-124.
-
(1988)
J Exp Zool
, vol.248
, pp. 121-124
-
-
Bartke, A.1
Steger, R.W.2
Hodges, S.L.3
Parkening, T.A.4
Collins, T.J.5
Yun, J.S.6
Wagner, T.E.7
-
49
-
-
0025831951
-
Fertility of transgenic female mice expressing bovine growth hormone or human growth hormone variant genes
-
Naar EM, Bartke A, Majumdar SS, Buonomo FC, Yun JS, Wagner TE: Fertility of transgenic female mice expressing bovine growth hormone or human growth hormone variant genes. Biol Reprod 1991;45:178-187.
-
(1991)
Biol Reprod
, vol.45
, pp. 178-187
-
-
Naar, E.M.1
Bartke, A.2
Majumdar, S.S.3
Buonomo, F.C.4
Yun, J.S.5
Wagner, T.E.6
-
50
-
-
0026650730
-
Transgenic female mice with high human growth hormone levels are fertile and capable of normal lactation without having been pregnant
-
Milton S, Cecim M, Li YS, Yun JS, Wagner TE, Bartke A: Transgenic female mice with high human growth hormone levels are fertile and capable of normal lactation without having been pregnant. Endocrinology 1992;131:536-538.
-
(1992)
Endocrinology
, vol.131
, pp. 536-538
-
-
Milton, S.1
Cecim, M.2
Li, Y.S.3
Yun, J.S.4
Wagner, T.E.5
Bartke, A.6
-
51
-
-
0024520438
-
The expression of a metallothionein-ovine growth hormone fusion gene in transgenic mice does not impair fertility but results in pathological lesions in the liver
-
Orian JM, Lee CS, Weiss LM, Brandon MR: The expression of a metallothionein-ovine growth hormone fusion gene in transgenic mice does not impair fertility but results in pathological lesions in the liver. Endocrinology 1989;124:455-463.
-
(1989)
Endocrinology
, vol.124
, pp. 455-463
-
-
Orian, J.M.1
Lee, C.S.2
Weiss, L.M.3
Brandon, M.R.4
-
52
-
-
0025775530
-
Acute effects of human growth hormone on liver cells in vitro: A comparison with livers of mice transgenic for human growth hormone
-
Vergani G, Mayerhofer A, Bartke A: Acute effects of human growth hormone on liver cells in vitro: A comparison with livers of mice transgenic for human growth hormone. Tissue Cell 1991;23:607-612.
-
(1991)
Tissue Cell
, vol.23
, pp. 607-612
-
-
Vergani, G.1
Mayerhofer, A.2
Bartke, A.3
-
53
-
-
0023945744
-
Progressive glomerulosclerosis develops in transgenic mice chronically expressing growth hormone and growth hormone releasing factor but not in those expressing insulinlike growth factor-I
-
Doi T, Striker LJ, Quaife C, Conti FG, Palmiter R, Behringer R, Brinster R, Striker GE: Progressive glomerulosclerosis develops in transgenic mice chronically expressing growth hormone and growth hormone releasing factor but not in those expressing insulinlike growth factor-I. Am J Pathol 1988;131:398-403.
-
(1988)
Am J Pathol
, vol.131
, pp. 398-403
-
-
Doi, T.1
Striker, L.J.2
Quaife, C.3
Conti, F.G.4
Palmiter, R.5
Behringer, R.6
Brinster, R.7
Striker, G.E.8
-
54
-
-
0026657439
-
Growth response and androgen receptor expression in seminal vesicles from aging transgenic mice expressing human or bovine growth hormone genes
-
Prins GS, Cecim M, Birch L, Wagner TE, Bartke A: Growth response and androgen receptor expression in seminal vesicles from aging transgenic mice expressing human or bovine growth hormone genes. Endocrinology 1992;131:2016-2023.
-
(1992)
Endocrinology
, vol.131
, pp. 2016-2023
-
-
Prins, G.S.1
Cecim, M.2
Birch, L.3
Wagner, T.E.4
Bartke, A.5
-
55
-
-
0026061059
-
The concentration of glial fibrillary acidic protein increases with age in the mouse and rat brain
-
O'Callaghan JP, Miller DB: The concentration of glial fibrillary acidic protein increases with age in the mouse and rat brain. Neurobiol Aging 1991;12:171-174.
-
(1991)
Neurobiol Aging
, vol.12
, pp. 171-174
-
-
O'Callaghan, J.P.1
Miller, D.B.2
-
56
-
-
0027939441
-
The role of the hippocampal mineralocorticoid and glucocorticoid receptors in the hypothalamo-pituitary-adrenal axis of the aged Fischer rat
-
Morano MI, Vazquez DM, Akil H: The role of the hippocampal mineralocorticoid and glucocorticoid receptors in the hypothalamo-pituitary- adrenal axis of the aged Fischer rat. Mol Cell Neurosci 1994;5:400-412.
-
(1994)
Mol Cell Neurosci
, vol.5
, pp. 400-412
-
-
Morano, M.I.1
Vazquez, D.M.2
Akil, H.3
-
57
-
-
0030614486
-
Decreased hypothalamic-pituitary-adrenal axis sensitivity to cortisol feedback inhibition in human aging
-
Wilkinson CW, Peskind ER, Raskind MA: Decreased hypothalamic-pituitary- adrenal axis sensitivity to cortisol feedback inhibition in human aging. Neuroendocrinology 1997;65:79-90.
-
(1997)
Neuroendocrinology
, vol.65
, pp. 79-90
-
-
Wilkinson, C.W.1
Peskind, E.R.2
Raskind, M.A.3
-
58
-
-
0031193957
-
Inhibitory avoidance and appetitive learning in aged normal mice: Comparison with transgenic mice having elevated plasma growth hormone levels
-
Meliska CJ, Burke PA, Bartke A, Jensen RA: Inhibitory avoidance and appetitive learning in aged normal mice: Comparison with transgenic mice having elevated plasma growth hormone levels. Neurobiol Learn Mem 1997;68:1-12.
-
(1997)
Neurobiol Learn Mem
, vol.68
, pp. 1-12
-
-
Meliska, C.J.1
Burke, P.A.2
Bartke, A.3
Jensen, R.A.4
-
59
-
-
0033494074
-
The growth hormone axis and cognition: Empirical results and integrated theory derived from giant transgenic mice
-
Rollo CD, Ko CV, Tyerman JG, Kajiura LJ: The growth hormone axis and cognition: Empirical results and integrated theory derived from giant transgenic mice. Can J Zool 1999;77:1874-1890.
-
(1999)
Can J Zool
, vol.77
, pp. 1874-1890
-
-
Rollo, C.D.1
Ko, C.V.2
Tyerman, J.G.3
Kajiura, L.J.4
-
60
-
-
0033037104
-
Loss of sensitivity to insulin at early events of the insulin signaling pathway in the liver of growth hormone-transgenic mice
-
Dominici FP, Cifone D, Bartke A, Turyn D: Loss of sensitivity to insulin at early events of the insulin signaling pathway in the liver of growth hormone-transgenic mice. J Endocrinol 1999;161:383-392.
-
(1999)
J Endocrinol
, vol.161
, pp. 383-392
-
-
Dominici, F.P.1
Cifone, D.2
Bartke, A.3
Turyn, D.4
-
61
-
-
0032883443
-
Alterations in the early steps of the insulin-signaling system in skeletal muscle of GH-transgenic mice
-
Dominici FP, Cifone D, Bartke A, Turyn D: Alterations in the early steps of the insulin-signaling system in skeletal muscle of GH-transgenic mice. Am J Physiol 1999;277:E447-E454.
-
(1999)
Am J Physiol
, vol.277
-
-
Dominici, F.P.1
Cifone, D.2
Bartke, A.3
Turyn, D.4
-
62
-
-
0028788807
-
Assessment of the primary adrenal cortical and pancreatic hormone basal levels in relation to plasma glucose and age in the unstressed Ames dwarf mouse
-
Borg KE, Brown-Borg HM, Bartke A: Assessment of the primary adrenal cortical and pancreatic hormone basal levels in relation to plasma glucose and age in the unstressed Ames dwarf mouse. Proc Soc Exp Biol Med 1995;210:126-133.
-
(1995)
Proc Soc Exp Biol Med
, vol.210
, pp. 126-133
-
-
Borg, K.E.1
Brown-Borg, H.M.2
Bartke, A.3
-
63
-
-
0036237480
-
Increased insulin sensitivity and upregulation of insulin receptor, insulin receptor substrate (IRS)-I and IRS-2 in liver of Ames dwarf mice
-
Dominici FP, Hauck S, Argentino DP, Bartke A, Turyn D: Increased insulin sensitivity and upregulation of insulin receptor, insulin receptor substrate (IRS)-I and IRS-2 in liver of Ames dwarf mice. J Endocrinol 2002;173:81-94.
-
(2002)
J Endocrinol
, vol.173
, pp. 81-94
-
-
Dominici, F.P.1
Hauck, S.2
Argentino, D.P.3
Bartke, A.4
Turyn, D.5
-
64
-
-
0033835911
-
Compensatory alterations of insulin signal transduction in liver of growth hormone receptor knockout mice
-
Dominici FP, Arostegui Diaz G, Bartke A, Kopchick JJ, Turyn D: Compensatory alterations of insulin signal transduction in liver of growth hormone receptor knockout mice. J Endocrinol 2000;166:579-590.
-
(2000)
J Endocrinol
, vol.166
, pp. 579-590
-
-
Dominici, F.P.1
Arostegui Diaz, G.2
Bartke, A.3
Kopchick, J.J.4
Turyn, D.5
-
65
-
-
0000689299
-
Accelerated aging of giant transgenic mice is associated with elevated free radical processes
-
Rollo CD, Carlson J, Sawada M: Accelerated aging of giant transgenic mice is associated with elevated free radical processes. Can J Zool 1996;74:606-620.
-
(1996)
Can J Zool
, vol.74
, pp. 606-620
-
-
Rollo, C.D.1
Carlson, J.2
Sawada, M.3
-
66
-
-
0032751474
-
Antioxidative mechanisms and plasma growth hormone levels
-
Brown-Borg HM, Bode AM, Bartke A: Antioxidative mechanisms and plasma growth hormone levels. Endocrine 1999;11:41-48.
-
(1999)
Endocrine
, vol.11
, pp. 41-48
-
-
Brown-Borg, H.M.1
Bode, A.M.2
Bartke, A.3
-
67
-
-
0035067195
-
Free radical defenses in the liver and kidney of human growth hormone transgenic mice: Possible mechanisms of early mortality
-
Hauck SJ, Bartke A: Free radical defenses in the liver and kidney of human growth hormone transgenic mice: Possible mechanisms of early mortality. J Gerontol A Biol Sci Med Sci 2001;56:B153-B162.
-
(2001)
J Gerontol A Biol Sci Med Sci
, vol.56
-
-
Hauck, S.J.1
Bartke, A.2
-
68
-
-
0030872731
-
Behavioural rhythmicity in transgenic growth hormone mice: Trade-offs, energetics, and sleep-wake cycles
-
Rollo CD, Foss J, Lachmansingh E, Singh R: Behavioural rhythmicity in transgenic growth hormone mice: Trade-offs, energetics, and sleep-wake cycles. Can J Zool 1997;75:1020-1034.
-
(1997)
Can J Zool
, vol.75
, pp. 1020-1034
-
-
Rollo, C.D.1
Foss, J.2
Lachmansingh, E.3
Singh, R.4
-
71
-
-
0032757405
-
Growth hormone: Fountain of youth or death hormone?
-
Morley JE: Growth hormone: Fountain of youth or death hormone? J Am Geriatr Soc 1999;47:1475-1476.
-
(1999)
J Am Geriatr Soc
, vol.47
, pp. 1475-1476
-
-
Morley, J.E.1
-
72
-
-
0034884345
-
Genes that prolong life: Relationships of growth hormone and growth to aging and life span
-
Bartke A, Coschigano K, Kopchick J, Chandrashekar V, Mattison J, Kinney B, Hauck S: Genes that prolong life: Relationships of growth hormone and growth to aging and life span. J Gerontol A Biol Sci Med Sci 2001;56:B340-B349.
-
(2001)
J Gerontol A Biol Sci Med Sci
, vol.56
-
-
Bartke, A.1
Coschigano, K.2
Kopchick, J.3
Chandrashekar, V.4
Mattison, J.5
Kinney, B.6
Hauck, S.7
-
73
-
-
0037231580
-
Insulin-like growth factor (IGF-1) and aging: Controversies and new insights
-
Bartke A, Chandrashekar V, Dominici FP, Turyn D, Kinney B, Steger RW, Kopchick JJ: Insulin-like growth factor (IGF-1) and aging: Controversies and new insights. Biogerontology 2003;4:1-8.
-
(2003)
Biogerontology
, vol.4
, pp. 1-8
-
-
Bartke, A.1
Chandrashekar, V.2
Dominici, F.P.3
Turyn, D.4
Kinney, B.5
Steger, R.W.6
Kopchick, J.J.7
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