Chronic rapamycin treatment or lack of S6K1 does not reduce ribosome activity in vivo

Cell Cycle

Volumn 12, Issue 15, 2013, Pages 2493-2504

  Garelick, Michael G ^a,c   MacKay, Vivian L ^a   Yanagida, Aya ^a   Academia, Emmeline C ^c   Schreiber, Katherine H ^c   Ladiges, Warren C ^b   Kennedy, Brian K ^a,c,d  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^d GUANGDONG MEDICAL UNIVERSITY   (China)

Author keywords

Aging; Rapamycin; S6 kinase; Signal transduction; TOR; Translation

Indexed keywords

RAPAMYCIN; S6 KINASE; S6K1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; DRUG EFFECT; ENZYME PHOSPHORYLATION; LONG TERM CARE; MOUSE; NONHUMAN; RIBOSOME; SINGLE DRUG DOSE; WILD TYPE;

INVERTEBRATA; MUS; VERTEBRATA;

AGING; RAPAMYCIN; S6 KINASE; SIGNAL TRANSDUCTION; TOR; TRANSLATION;

ANIMALS; LIVER; LONGEVITY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SKELETAL; PHOSPHORYLATION; POLYRIBOSOMES; PROTEIN PROCESSING, POST-TRANSLATIONAL; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84881483132     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.25512     Document Type: Article

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