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Volumn 9, Issue 4, 2017, Pages

Beyond the cholesterol-lowering effect of soy protein: A review of the effects of dietary soy and its constituents on risk factors for cardiovascular disease

Author keywords

Cardiovascular disease; Cholesterol; Dietary soy; Functional foods; Isoflavones; Lipids; Obesity; Soy protein

Indexed keywords

C REACTIVE PROTEIN; HYPOCHOLESTEROLEMIC AGENT; ISOFLAVONE; PHOSPHATIDYLCHOLINE; SAPONIN; SOYBEAN PROTEIN; TRIACYLGLYCEROL; BIOLOGICAL MARKER; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; ISOFLAVONE DERIVATIVE; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 85016146111     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu9040324     Document Type: Review
Times cited : (215)

References (159)
  • 2
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis—An inflammatory disease
    • [CrossRef]
    • Ross, R. Atherosclerosis—An inflammatory disease. N. Engl. J. Med. 1999, 340, 115-126. [CrossRef]
    • (1999) N. Engl. J. Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 3
    • 0029886630 scopus 로고    scopus 로고
    • Blood pressure as a cardiovascular risk factor: Prevention and treatment
    • [CrossRef][PubMed]
    • Kannel, W.B. Blood pressure as a cardiovascular risk factor: Prevention and treatment. JAMA 1996, 275, 1571-1576. [CrossRef] [PubMed]
    • (1996) JAMA , vol.275 , pp. 1571-1576
    • Kannel, W.B.1
  • 4
    • 0035464874 scopus 로고    scopus 로고
    • Hyperglycemia and cardiovascular disease
    • [CrossRef][PubMed]
    • Duckworth, W.C. Hyperglycemia and cardiovascular disease. Curr. Atheroscler. Rep. 2001, 3, 383-391. [CrossRef] [PubMed]
    • (2001) Curr. Atheroscler. Rep , vol.3 , pp. 383-391
    • Duckworth, W.C.1
  • 5
    • 20444412299 scopus 로고    scopus 로고
    • Oxidative stress and atherosclerosis
    • [CrossRef]
    • Schulze, P.C.; Lee, R.T. Oxidative stress and atherosclerosis. Curr. Atherscler. Rep. 2005, 7, 242-248. [CrossRef]
    • (2005) Curr. Atherscler. Rep , vol.7 , pp. 242-248
    • Schulze, P.C.1    Lee, R.T.2
  • 6
    • 84875126584 scopus 로고    scopus 로고
    • Nutritional quality of legumes, and their role in cardiometabolic risk prevention: A review
    • [CrossRef][PubMed]
    • Bouchenak, M.; Lamri-Senhadji, M. Nutritional quality of legumes, and their role in cardiometabolic risk prevention: A review. J. Med. Food 2013, 16, 185-198. [CrossRef] [PubMed]
    • (2013) J. Med. Food , vol.16 , pp. 185-198
    • Bouchenak, M.1    Lamri-Senhadji, M.2
  • 8
    • 38749088374 scopus 로고    scopus 로고
    • Functional and edible uses of soy protein products
    • [CrossRef]
    • Singh, P.; Kumar, R.; Sabapathy, S.N.; Bawa, A.S. Functional and edible uses of soy protein products. CRFSFS 2008, 7, 14-28. [CrossRef]
    • (2008) CRFSFS , vol.7 , pp. 14-28
    • Singh, P.1    Kumar, R.2    Sabapathy, S.N.3    Bawa, A.S.4
  • 9
    • 33746102594 scopus 로고    scopus 로고
    • Regulation of lipid metabolism by soy protein and its implication in diseases mediated by lipid disorders
    • [CrossRef][PubMed]
    • Torres, N.; Torre-Villalvazo, I.; Tovar, A.R. Regulation of lipid metabolism by soy protein and its implication in diseases mediated by lipid disorders. J. Nutr. Biochem. 2006, 17, 365-373. [CrossRef] [PubMed]
    • (2006) J. Nutr. Biochem , vol.17 , pp. 365-373
    • Torres, N.1    Torre-Villalvazo, I.2    Tovar, A.R.3
  • 10
    • 78649660818 scopus 로고    scopus 로고
    • Effects of soy protein on lipoprotein lipids and fecal bile acid excretion in men and women with moderate hypercholesterolemia
    • [CrossRef][PubMed]
    • Maki, K.C.; Butteiger, D.N.; Rains, T.M. Effects of soy protein on lipoprotein lipids and fecal bile acid excretion in men and women with moderate hypercholesterolemia. J. Clin. Lipidol. 2010, 4, 531-542. [CrossRef] [PubMed]
    • (2010) J. Clin. Lipidol , vol.4 , pp. 531-542
    • Maki, K.C.1    Butteiger, D.N.2    Rains, T.M.3
  • 11
    • 0029056306 scopus 로고
    • Meta-analysis of the effects of soy-protein intake on serum lipids
    • [CrossRef][PubMed]
    • Anderson, J.W.; Johnston, B.M.; Cook-Newell, M.E. Meta-analysis of the effects of soy-protein intake on serum lipids. N. Engl. J. Med. 1995, 333, 276-282. [CrossRef] [PubMed]
    • (1995) N. Engl. J. Med , vol.333 , pp. 276-282
    • Anderson, J.W.1    Johnston, B.M.2    Cook-Newell, M.E.3
  • 12
    • 0043025572 scopus 로고    scopus 로고
    • Relation between soy-associated isoflavones and LDL and HDL cholesterol concentrations in humans: A meta-analysis
    • [CrossRef][PubMed]
    • Weggemans, R.M.; Trautwein, E.A. Relation between soy-associated isoflavones and LDL and HDL cholesterol concentrations in humans: A meta-analysis. Eur. J. Clin. Nutr. 2003, 57, 940-946. [CrossRef] [PubMed]
    • (2003) Eur. J. Clin. Nutr , vol.57 , pp. 940-946
    • Weggemans, R.M.1    Trautwein, E.A.2
  • 13
    • 3042543745 scopus 로고    scopus 로고
    • Effects of isoflavones (Soy phyto-estrogens) on serum lipids: A meta-analysis of randomized controlled trials
    • [CrossRef][PubMed]
    • Yueng, J.; Yu, T.F. Effects of isoflavones (soy phyto-estrogens) on serum lipids: A meta-analysis of randomized controlled trials. Nutr. J. 2003, 2, 1-8. [CrossRef] [PubMed]
    • (2003) Nutr. J , vol.2 , pp. 1-8
    • Yueng, J.1    Yu, T.F.2
  • 14
    • 4444292230 scopus 로고    scopus 로고
    • Soy isoflavone intake lowers serum LDL cholesterol: A meta-analysis of 8 randomized controlled trials in humans
    • [PubMed]
    • Zhuo, X.-G.; Melby, M.K.; Watanabe, S. Soy isoflavone intake lowers serum LDL cholesterol: A meta-analysis of 8 randomized controlled trials in humans. J. Nutr. 2004, 134, 2395-2400. [PubMed]
    • (2004) J. Nutr , vol.134 , pp. 2395-2400
    • Zhuo, X.-G.1    Melby, M.K.2    Watanabe, S.3
  • 15
    • 14544279414 scopus 로고    scopus 로고
    • Meta-analysis of the effects of soy-protein containing isoflavones on the lipid profile
    • [PubMed]
    • Zhan, S.; Ho, S.C. Meta-analysis of the effects of soy-protein containing isoflavones on the lipid profile. Am. J. Clin. Nutr. 2005, 81, 397-408. [PubMed]
    • (2005) Am. J. Clin. Nutr , vol.81 , pp. 397-408
    • Zhan, S.1    Ho, S.C.2
  • 16
    • 33747164818 scopus 로고    scopus 로고
    • Meta-analysis of the effect of soy protein supplementation on serum lipids
    • [CrossRef][PubMed]
    • Reynolds, K.; Chin, A.; Lees, K.A.; Nguyen, A.; Bujnowski, D.; He, J. A meta-analysis of the effect of soy protein supplementation on serum lipids. Am. J. Cardiol. 2006, 98, 633-640. [CrossRef] [PubMed]
    • (2006) Am. J. Cardiol , vol.98 , pp. 633-640
    • Reynolds, K.1    Chin, A.2    Lees, K.A.3    Nguyen, A.4    Bujnowski, D.5    He, J.A.6
  • 17
    • 34147144498 scopus 로고    scopus 로고
    • Soy isoflavones lower serum total and LDL cholesterol in humans: A meta-analysis of 11 randomized controlled trials
    • [PubMed]
    • Taku, K.; Umegaki, K.; Sato, Y.; Taki, Y.; Endoh, K.; Watanabe, S. Soy isoflavones lower serum total and LDL cholesterol in humans: A meta-analysis of 11 randomized controlled trials. Am. J. Clin. Nutr. 2007, 85, 1148-1156. [PubMed]
    • (2007) Am. J. Clin. Nutr , vol.85 , pp. 1148-1156
    • Taku, K.1    Umegaki, K.2    Sato, Y.3    Taki, Y.4    Endoh, K.5    Watanabe, S.6
  • 18
    • 56749117731 scopus 로고    scopus 로고
    • Effects of extracted soy isoflavones alone on blood total and LDL cholesterol: Meta-analysis of randomized controlled trials
    • [CrossRef][PubMed]
    • Taku, K.; Umegaki, K.; Ishimi, Y.; Watanabe, S. Effects of extracted soy isoflavones alone on blood total and LDL cholesterol: Meta-analysis of randomized controlled trials. Ther. Clin. Risk Manag. 2008, 4, 1097-1103. [CrossRef] [PubMed]
    • (2008) Ther. Clin. Risk Manag , vol.4 , pp. 1097-1103
    • Taku, K.1    Umegaki, K.2    Ishimi, Y.3    Watanabe, S.4
  • 19
    • 49949113351 scopus 로고    scopus 로고
    • Systematic review, meta-analysis and regression of randomised controlled trials reporting an association between an intake of circa 25 g soya protein per day and blood cholesterol
    • [CrossRef][PubMed]
    • Harland, J.I.; Haffner, T.A. Systematic review, meta-analysis and regression of randomised controlled trials reporting an association between an intake of circa 25 g soya protein per day and blood cholesterol. Atherosclerosis 2008, 200, 13-27. [CrossRef] [PubMed]
    • (2008) Atherosclerosis , vol.200 , pp. 13-27
    • Harland, J.I.1    Haffner, T.A.2
  • 22
    • 85016140362 scopus 로고    scopus 로고
    • (accessed on 28 September 2016)
    • U.S. Food & Drug Administration. Available online: http://www.fda.gov/Food/GuidanceRegulation/GuidanceDocumentsRegulatoryInformation/LabelingNutrition/ucm064919.htm(accessed on 28 September 2016).
  • 23
    • 85016142222 scopus 로고    scopus 로고
    • (accessed on 28 September 2016)
    • Health Canada: Summary of Health Canada’s Assessment of a Health Claim about Soy Protein and Cholesterol Lowering. Available online: http://www.hc-sc.gc.ca/fn-an/label-etiquet/claims-reclam/ assess-evalu/soy-protein-cholesterol-eng.php (accessed on 28 September 2016).
  • 24
    • 85016142039 scopus 로고    scopus 로고
    • (accessed on 29 January 2017)
    • European Food Safety Authority. Scientific Opinion on the Substantiation of a Health Claim Related to Isolated Soy Protein and Reduction of Blood LDL-Cholesterol Concentrations Pursuant to Article 14 of Regulation (EC) No 1924/2006. Available online: http://www.efsa.europa.eu/en/efsajournal/pub/2555 (accessed on 29 January 2017).
  • 25
    • 85016144347 scopus 로고    scopus 로고
    • Soybean Constituents and Their Functional Benefits
    • (accessed on 10 January 2017)
    • Dixit, A.K.; Antony, J.I.X.; Sharma, N.K.; Tiwari, R.K. Soybean Constituents and Their Functional Benefits. Opportunity. Available online: http://www.trnres.com/ebook/uploads/tiwari/T_1302158885Tiwari-12.pdf (accessed on 10 January 2017).
    • Opportunity
    • Dixit, A.K.1    Antony, J.I.X.2    Sharma, N.K.3    Tiwari, R.K.4
  • 26
    • 5444258710 scopus 로고    scopus 로고
    • Health benefits of soy isoflavonoids and strategies for enhancement: A review
    • [CrossRef][PubMed]
    • McCue, P.; Kalidas, S. Health benefits of soy isoflavonoids and strategies for enhancement: A review. Crit. Rev. Food Sci. Nutr. 2004, 44, 361-367. [CrossRef] [PubMed]
    • (2004) Crit. Rev. Food Sci. Nutr , vol.44 , pp. 361-367
    • McCue, P.1    Kalidas, S.2
  • 30
    • 23844554843 scopus 로고    scopus 로고
    • Soybean foods and their benefits: Potential mechanisms of action
    • [CrossRef][PubMed]
    • Omoni, A.O.; Aluko, R.E. Soybean foods and their benefits: Potential mechanisms of action. Nutr. Rev. 2005, 63, 272-283. [CrossRef] [PubMed]
    • (2005) Nutr. Rev , vol.63 , pp. 272-283
    • Omoni, A.O.1    Aluko, R.E.2
  • 31
    • 84867311271 scopus 로고    scopus 로고
    • Systematic reviews and metaand pooled analyses dietary protein intake and blood pressure: A meta-analysis of randomized controlled trials
    • [CrossRef][PubMed]
    • Rebholz, C.M.; Friedman, E.E.; Powers, L.J.; Arroyave, W.D.; He, J.; Kelly, T.N. Systematic reviews and metaand pooled analyses dietary protein intake and blood pressure: A meta-analysis of randomized controlled trials. Am. J. Epidemiol. 2012, 176, S27-S43. [CrossRef] [PubMed]
    • (2012) Am. J. Epidemiol , vol.176 , pp. S27-S43
    • Rebholz, C.M.1    Friedman, E.E.2    Powers, L.J.3    Arroyave, W.D.4    He, J.5    Kelly, T.N.6
  • 33
    • 84960077861 scopus 로고    scopus 로고
    • Phytoestrogens in health: The role of isoflavones
    • Preedy, V.R., Ed.; RSC Publishing: Cambridge, UK
    • Baber, R.J. Phytoestrogens in health: The role of isoflavones. In Isoflavones: Chemistry, Analysis, Function and Effects; Preedy, V.R., Ed.; RSC Publishing: Cambridge, UK, 2011.
    • (2011) In Isoflavones: Chemistry, Analysis, Function and Effects;
    • Baber, R.J.1
  • 35
    • 85011702226 scopus 로고    scopus 로고
    • Dietary soy and natto intake and cardiovascular disease mortality in Japanese adults: The Takayama study
    • [CrossRef][PubMed]
    • Nagata, C.; Wada, K.; Tamura, T.; Konishi, K.; Goto, Y.; Koda, S.; Kawachi, T.; Tsuji, M.; Nakamura, K. Dietary soy and natto intake and cardiovascular disease mortality in Japanese adults: The Takayama study. Am. J. Clin. Nutr. 2016, 105, 426-431. [CrossRef] [PubMed]
    • (2016) Am. J. Clin. Nutr , vol.105 , pp. 426-431
    • Nagata, C.1    Wada, K.2    Tamura, T.3    Konishi, K.4    Goto, Y.5    Koda, S.6    Kawachi, T.7    Tsuji, M.8    Nakamura, K.9
  • 36
    • 78649569497 scopus 로고    scopus 로고
    • Whole versus the piecemeal approach to evaluating soy
    • [CrossRef][PubMed]
    • Reinwald, S.; Akabas, S.R.; Weaver, C.M. Whole versus the piecemeal approach to evaluating soy. J. Nutr. 2010, 140, 2335S-2343S. [CrossRef] [PubMed]
    • (2010) J. Nutr , vol.140 , pp. 2335S-2343S
    • Reinwald, S.1    Akabas, S.R.2    Weaver, C.M.3
  • 37
    • 77953751445 scopus 로고    scopus 로고
    • Equol: History, chemistry, and formation
    • [CrossRef][PubMed]
    • Setchell, K.D.R.; Clerici, C. Equol: History, chemistry, and formation. J. Nutr. 2010, 140, 1355S-1362S. [CrossRef] [PubMed]
    • (2010) J. Nutr , vol.140 , pp. 1355S-1362S
    • Setchell, K.D.R.1    Clerici, C.2
  • 38
    • 84895772687 scopus 로고    scopus 로고
    • Cardiovascular risks in relation to daidzein metabolizing phenotypes among Chinese postmenopausal women
    • [CrossRef][PubMed]
    • Liu, Z.M.; Ho, S.C.; Chen, Y.M.; Liu, J.; Woo, J. Cardiovascular risks in relation to daidzein metabolizing phenotypes among Chinese postmenopausal women. PLoS ONE 2014, 9, e87861. [CrossRef] [PubMed]
    • (2014) Plos ONE , vol.9
    • Liu, Z.M.1    Ho, S.C.2    Chen, Y.M.3    Liu, J.4    Woo, J.5
  • 39
    • 33746620197 scopus 로고    scopus 로고
    • One-month exposure to soy isoflavones did not induce the ability to produce equol in postmenopausal women
    • [CrossRef][PubMed]
    • Vedrine, N.; Mathey, J.; Morand, C.; Brandolini, M.; Davicco, M.-J.; Guy, L.; Remesy, C.; Coxam, V.; Manach, C. One-month exposure to soy isoflavones did not induce the ability to produce equol in postmenopausal women. Eur. J. Clin. Nutr. 2006, 60, 1039-1045. [CrossRef] [PubMed]
    • (2006) Eur. J. Clin. Nutr , vol.60 , pp. 1039-1045
    • Vedrine, N.1    Mathey, J.2    Morand, C.3    Brandolini, M.4    Davicco, M.-J.5    Guy, L.6    Remesy, C.7    Coxam, V.8    Manach, C.9
  • 40
    • 73749083601 scopus 로고    scopus 로고
    • Influence of ethnic origin (Asian v. Caucasian) and background diet on the bioavailability of dietary isoflavones
    • [CrossRef][PubMed]
    • Vergne, S.; Sauvant, P.; Lamothe, V.; Chantre, P. Influence of ethnic origin (Asian v. Caucasian) and background diet on the bioavailability of dietary isoflavones. Br. J. Nutr. 2009, 102, 1642-1653. [CrossRef] [PubMed]
    • (2009) Br. J. Nutr , vol.102 , pp. 1642-1653
    • Vergne, S.1    Sauvant, P.2    Lamothe, V.3    Chantre, P.4
  • 41
    • 32444434806 scopus 로고    scopus 로고
    • Worldwide epidemic of obesity: Hope for Japanese diets
    • [CrossRef][PubMed]
    • Yamori, Y.Worldwide epidemic of obesity: Hope for Japanese diets. Clin. Exp. Pharmacol. Physiol. 2004, 31, 2-4. [CrossRef] [PubMed]
    • (2004) Clin. Exp. Pharmacol. Physiol , vol.31 , pp. 2-4
    • Yamori, Y.1
  • 43
    • 84954362715 scopus 로고    scopus 로고
    • Fruit and vegetable consumption and the incidence of hypertension in three prospective cohort studies
    • [CrossRef][PubMed]
    • Borgi, L.; Muraki, I.; Satija, A.; Willett, W.C.; Rimm, E.B.; Forman, J.P. Fruit and vegetable consumption and the incidence of hypertension in three prospective cohort studies. Hypertension 2016, 67, 288-293. [CrossRef] [PubMed]
    • (2016) Hypertension , vol.67 , pp. 288-293
    • Borgi, L.1    Muraki, I.2    Satija, A.3    Willett, W.C.4    Rimm, E.B.5    Forman, J.P.6
  • 44
    • 84924617366 scopus 로고    scopus 로고
    • Dietary phytochemical index is inversely associated with the occurrence of hypertension in adults: A 3-year follow-up (the Tehran Lipid and Glucose Study)
    • [CrossRef][PubMed]
    • Golzarand, M.; Bahadoran, Z.; Mirmiran, P.; Sadeghian-Sharif, S.; Azizi, F. Dietary phytochemical index is inversely associated with the occurrence of hypertension in adults: A 3-year follow-up (the Tehran Lipid and Glucose Study). Eur. J. Clin. Nutr. 2015, 69, 392-398. [CrossRef] [PubMed]
    • (2015) Eur. J. Clin. Nutr , vol.69 , pp. 392-398
    • Golzarand, M.1    Bahadoran, Z.2    Mirmiran, P.3    Sadeghian-Sharif, S.4    Azizi, F.5
  • 45
    • 84888417829 scopus 로고    scopus 로고
    • Effects of soybean product intake on fasting and postload hyperglycemia and type 2 diabetes in Japanese men with high body mass index: The Saku Study
    • [CrossRef][PubMed]
    • Tatsumi, Y.; Morimoto, A.; Deura, K.; Mizuno, S.; Ohno, Y.; Watanabe, S. Effects of soybean product intake on fasting and postload hyperglycemia and type 2 diabetes in Japanese men with high body mass index: The Saku Study. J. Diabetes Investig. 2013, 4, 626-633. [CrossRef] [PubMed]
    • (2013) J. Diabetes Investig , vol.4 , pp. 626-633
    • Tatsumi, Y.1    Morimoto, A.2    Deura, K.3    Mizuno, S.4    Ohno, Y.5    Watanabe, S.6
  • 46
    • 77249125353 scopus 로고    scopus 로고
    • Soy product and isoflavone intakes are associated with a lower risk of type 2 diabetes in overweight Japanese women
    • [PubMed]
    • Nanri, A.; Mizoue, T.; Takahashi, Y.; Kirii, K.; Inoue, M.; Noda, M.; Tsugane, S. Soy product and isoflavone intakes are associated with a lower risk of type 2 diabetes in overweight Japanese women. J. Nutr. 2010, 140, 580-586. [PubMed]
    • (2010) J. Nutr , vol.140 , pp. 580-586
    • Nanri, A.1    Mizoue, T.2    Takahashi, Y.3    Kirii, K.4    Inoue, M.5    Noda, M.6    Tsugane, S.7
  • 48
    • 84978081681 scopus 로고    scopus 로고
    • Consumption of soy foods and isoflavones and risk of type 2 diabetes: A pooled analysis of three US cohorts
    • [CrossRef][PubMed]
    • Ding, M.; Pan, A.; Manson, J.E.; Willett, W.C.; Malik, V.; Rosner, B.; Giovannucci, E.; Hu, F.B.; Sun, Q. Consumption of soy foods and isoflavones and risk of type 2 diabetes: A pooled analysis of three US cohorts. Eur. J. Clin. Nutr. 2016, 70, 1381-1387. [CrossRef] [PubMed]
    • (2016) Eur. J. Clin. Nutr , vol.70 , pp. 1381-1387
    • Ding, M.1    Pan, A.2    Manson, J.E.3    Willett, W.C.4    Malik, V.5    Rosner, B.6    Giovannucci, E.7    Hu, F.B.8    Sun, Q.9
  • 49
    • 79651473816 scopus 로고    scopus 로고
    • Soy consumption is not protective against diabetes in Hawaii: The multiethnic cohort
    • [CrossRef][PubMed]
    • Morimoto, Y.; Steinbrehcer, A.; Kolonel, L.; Maskarinec, G. Soy consumption is not protective against diabetes in Hawaii: The multiethnic cohort. Eur. J. Clin. Nutr. 2011, 65, 279-282. [CrossRef] [PubMed]
    • (2011) Eur. J. Clin. Nutr , vol.65 , pp. 279-282
    • Morimoto, Y.1    Steinbrehcer, A.2    Kolonel, L.3    Maskarinec, G.4
  • 50
    • 84961233828 scopus 로고    scopus 로고
    • Wang, H. Soy consumption with risk of coronary heart disease and stroke: A meta-analysis of observational studies
    • [CrossRef][PubMed]
    • Lou, D.; Li, Y.; Yan, G.; Bu, J.; Wang, H. Soy consumption with risk of coronary heart disease and stroke: A meta-analysis of observational studies. Neuroepidemiology 2016, 46, 242-252. [CrossRef] [PubMed]
    • (2016) Neuroepidemiology , vol.46 , pp. 242-252
    • Lou, D.1    Li, Y.2    Yan, G.3    Bu, J.4
  • 51
    • 85016150890 scopus 로고    scopus 로고
    • Diseases of the cardiovascular system
    • Nelms, M., Sucher, K., Long, S., Eds.; Thomson Brooks/Cole: Belmont, CA, USA
    • Pujol, T.J.; Tucker, J.E. Diseases of the cardiovascular system. In Nutrition Therapy and Pathophysiology; Nelms, M., Sucher, K., Long, S., Eds.; Thomson Brooks/Cole: Belmont, CA, USA, 2007; pp. 371-415.
    • (2007) Nutrition Therapy and Pathophysiology , pp. 371-415
    • Pujol, T.J.1    Tucker, J.E.2
  • 52
    • 12744273390 scopus 로고    scopus 로고
    • Genetic variations related to hypertension: A review
    • [CrossRef][PubMed]
    • Tanira, M.O.; Al Balushi, K.A. Genetic variations related to hypertension: A review. J. Hum. Hypertens. 2005, 19, 7-19. [CrossRef] [PubMed]
    • (2005) J. Hum. Hypertens , vol.19 , pp. 7-19
    • Tanira, M.O.1    Al Balushi, K.A.2
  • 53
    • 79960722812 scopus 로고    scopus 로고
    • Emerging evidence of the health benefits of S-equol, an estrogen receptor β-agonist
    • [CrossRef][PubMed]
    • Jackson, R.L.; Greiwe, J.S.; Schwen, R.J. Emerging evidence of the health benefits of S-equol, an estrogen receptor β-agonist. Nutr. Rev. 2011, 69, 432-448. [CrossRef] [PubMed]
    • (2011) Nutr. Rev , vol.69 , pp. 432-448
    • Jackson, R.L.1    Greiwe, J.S.2    Schwen, R.J.3
  • 55
    • 84951842492 scopus 로고    scopus 로고
    • Inhibition of angiotensin converting enzyme, angiotensin II receptor blocking, and blood pressure lowering bioactivity across plant families
    • [CrossRef][PubMed]
    • Patten, G.S.; Abeywardena, M.Y.; Bennett, L.E. Inhibition of angiotensin converting enzyme, angiotensin II receptor blocking, and blood pressure lowering bioactivity across plant families. Crit. Rev. Food Sci. Nutr. 2016, 56, 181-214. [CrossRef] [PubMed]
    • (2016) Crit. Rev. Food Sci. Nutr , vol.56 , pp. 181-214
    • Patten, G.S.1    Abeywardena, M.Y.2    Bennett, L.E.3
  • 56
    • 77957253371 scopus 로고    scopus 로고
    • Effects of soy isoflavone extract supplements on blood pressure in adult humans: Systematic review and meta-analysis of randomized placebo-controlled trials
    • [CrossRef][PubMed]
    • Taku, K.; Lin, N.; Cai, D.; Hu, J.; Zhao, X.; Zhang, Y.; Wang, P.; Melby, M.K.; Hooper, L.; Kurzer, M.S., et al. Effects of soy isoflavone extract supplements on blood pressure in adult humans: Systematic review and meta-analysis of randomized placebo-controlled trials. J. Hypertens. 2010, 28, 1971-1982. [CrossRef] [PubMed]
    • (2010) J. Hypertens , vol.28 , pp. 1971-1982
    • Taku, K.1    Lin, N.2    Cai, D.3    Hu, J.4    Zhao, X.5    Zhang, Y.6    Wang, P.7    Melby, M.K.8    Hooper, L.9    Kurzer, M.S.10
  • 57
    • 84861201786 scopus 로고    scopus 로고
    • Effect of soy isoflavones on blood pressure: A meta-analysis of randomized controlled trials
    • [CrossRef][PubMed]
    • Liu, X.X.; Li, S.H.; Chen, J.Z.; Sun, K.; Wang, X.J.; Wang, X.G.; Hui, R.T. Effect of soy isoflavones on blood pressure: A meta-analysis of randomized controlled trials. Nutr. Metab. Cardiovasc. Dis. 2012, 22, 463-470. [CrossRef] [PubMed]
    • (2012) Nutr. Metab. Cardiovasc. Dis , vol.22 , pp. 463-470
    • Liu, X.X.1    Li, S.H.2    Chen, J.Z.3    Sun, K.4    Wang, X.J.5    Wang, X.G.6    Hui, R.T.7
  • 59
    • 84958167093 scopus 로고    scopus 로고
    • Polyphenol protection and treatment of hypertension
    • [CrossRef][PubMed]
    • Hügel, H.M.; Jackson, N.; May, B.; Zhang, A.L.; Xue, C.C. Polyphenol protection and treatment of hypertension. Phytomedicine 2016, 23, 220-231. [CrossRef] [PubMed]
    • (2016) Phytomedicine , vol.23 , pp. 220-231
    • Hügel, H.M.1    Jackson, N.2    May, B.3    Zhang, A.L.4    Xue, C.C.5
  • 60
    • 84959925870 scopus 로고    scopus 로고
    • Acute benefits of the microbial-derived isoflavone metabolite equol on arterial stiffness in men prospectively recruited according to equol producer phenotype: A double-blind randomized controlled trial
    • [CrossRef][PubMed]
    • Hazim, S.; Curtis, P.J.; Schär, M.Y.; Ostertag, L.M.; Kay, C.D.; Minihane, A.-M.; Cassidy, A. Acute benefits of the microbial-derived isoflavone metabolite equol on arterial stiffness in men prospectively recruited according to equol producer phenotype: A double-blind randomized controlled trial. Am. J. Clin. Nutr. 2016, 103, 694-702. [CrossRef] [PubMed]
    • (2016) Am. J. Clin. Nutr , vol.103 , pp. 694-702
    • Hazim, S.1    Curtis, P.J.2    Schär, M.Y.3    Ostertag, L.M.4    Kay, C.D.5    Minihane, A.-M.6    Cassidy, A.7
  • 61
    • 84920578789 scopus 로고    scopus 로고
    • Effect of soy nuts and equol status on blood pressure, lipids and inflammation in postmenopausal women stratified by metabolic syndrome status
    • [CrossRef][PubMed]
    • Acharjee, S.; Zhou, J.; Elajami, T.K.; Welty, F.K. Effect of soy nuts and equol status on blood pressure, lipids and inflammation in postmenopausal women stratified by metabolic syndrome status. Metabolism 2015, 64, 236-243. [CrossRef] [PubMed]
    • (2015) Metabolism , vol.64 , pp. 236-243
    • Acharjee, S.1    Zhou, J.2    Elajami, T.K.3    Welty, F.K.4
  • 62
    • 84943666303 scopus 로고    scopus 로고
    • Effect of whole soy and purified daidzein on ambulatory blood pressure and endothelial function—A 6-month double-blind, randomized controlled trial among Chinese postmenopausal women with prehypertension
    • [CrossRef][PubMed]
    • Liu, Z.; Ho, S.C.; Chen, Y.; Tomlinson, B.; Ho, S.; To, K.; Woo, J. Effect of whole soy and purified daidzein on ambulatory blood pressure and endothelial function—A 6-month double-blind, randomized controlled trial among Chinese postmenopausal women with prehypertension. Eur. J. Clin. Nutr. 2015, 69, 1161-1168. [CrossRef] [PubMed]
    • (2015) Eur. J. Clin. Nutr , vol.69 , pp. 1161-1168
    • Liu, Z.1    Ho, S.C.2    Chen, Y.3    Tomlinson, B.4    Ho, S.5    To, K.6    Woo, J.7
  • 63
    • 84983350453 scopus 로고    scopus 로고
    • Soy pulp extract inhibits angiotensin I-converting enzyme (ACE) activity in vitro: Evidence for its potential hypertension-improving action
    • [CrossRef][PubMed]
    • Nishibori, N.; Kishibuchi, R.; Morita, K. Soy pulp extract inhibits angiotensin I-converting enzyme (ACE) activity in vitro: Evidence for its potential hypertension-improving action. J. Diet. Suppl. 2017, 14, 241-251. [CrossRef] [PubMed]
    • (2017) J. Diet , vol.14 , pp. 241-251
    • Nishibori, N.1    Kishibuchi, R.2    Morita, K.3
  • 65
    • 84872874053 scopus 로고    scopus 로고
    • Effect of soy protein and isoflavones on blood pressure and endothelial cytokines: A 6-month randomized controlled trial among postmenopausal women
    • [CrossRef][PubMed]
    • Liu, Z.M.; Ho, S.C.; Chen, Y.M.; Woo, J. Effect of soy protein and isoflavones on blood pressure and endothelial cytokines: A 6-month randomized controlled trial among postmenopausal women. J. Hypertens. 2013, 31, 382-392. [CrossRef] [PubMed]
    • (2013) J. Hypertens , vol.31 , pp. 382-392
    • Liu, Z.M.1    Ho, S.C.2    Chen, Y.M.3    Woo, J.4
  • 66
    • 34249737604 scopus 로고    scopus 로고
    • Effect of soy nuts on blood pressure and lipid levels in hypertensive, prehypertensive, and normotensive postmenopausal women
    • [CrossRef][PubMed]
    • Welty, F.K.; Lee, K.S.; Lew, N.S.; Zhou, J.R. Effect of soy nuts on blood pressure and lipid levels in hypertensive, prehypertensive, and normotensive postmenopausal women. Arch. Intern. Med. 2007, 167, 1060-1067. [CrossRef] [PubMed]
    • (2007) Arch. Intern. Med , vol.167 , pp. 1060-1067
    • Welty, F.K.1    Lee, K.S.2    Lew, N.S.3    Zhou, J.R.4
  • 67
    • 84925395796 scopus 로고    scopus 로고
    • The anti-obesity and anti-diabetic effects of kaempferol glycosides from unripe soybean leaves in high-fat-diet mice
    • [CrossRef][PubMed]
    • Zang, Y.; Zhang, L.; Igarashi, K.; Yu, C. The anti-obesity and anti-diabetic effects of kaempferol glycosides from unripe soybean leaves in high-fat-diet mice. Food Funct. 2015, 6, 834-841. [CrossRef] [PubMed]
    • (2015) Food Funct , vol.6 , pp. 834-841
    • Zang, Y.1    Zhang, L.2    Igarashi, K.3    Yu, C.4
  • 68
    • 84929660820 scopus 로고    scopus 로고
    • The effect of tree nut, peanut, and soy nut consumption on blood pressure: A systematic review and meta-analysis of randomized controlled clinical trials
    • [CrossRef][PubMed]
    • Mohammadifard, N.; Salehi-Abargouei, A.; Salas-Salvadó, J.; Guasch-Ferré, M.; Humphries, K.; Sarrafzadegan, N. The effect of tree nut, peanut, and soy nut consumption on blood pressure: A systematic review and meta-analysis of randomized controlled clinical trials. Am. J. Clin. Nutr. 2015, 101, 966-982. [CrossRef] [PubMed]
    • (2015) Am. J. Clin. Nutr , vol.101 , pp. 966-982
    • Mohammadifard, N.1    Salehi-Abargouei, A.2    Salas-Salvadó, J.3    Guasch-Ferré, M.4    Humphries, K.5    Sarrafzadegan, N.6
  • 69
    • 84934899108 scopus 로고    scopus 로고
    • The effects of soy bean flour enriched bread intake on anthropometric indices and blood pressure in type 2 diabetic women: A crossover randomized controlled clinical trial
    • [CrossRef][PubMed]
    • Moghaddam, A.S.; Entezari, M.H.; Iraj, B.; Gholamreza, A.; Zahabi, E.S.; Maracy, M.R. The effects of soy bean flour enriched bread intake on anthropometric indices and blood pressure in type 2 diabetic women: A crossover randomized controlled clinical trial. Int. J. Endocrinol. 2014, 2014, 240760. [CrossRef] [PubMed]
    • (2014) Int. J. Endocrinol , vol.2014
    • Moghaddam, A.S.1    Entezari, M.H.2    Iraj, B.3    Gholamreza, A.4    Zahabi, E.S.5    Maracy, M.R.6
  • 70
    • 33846237260 scopus 로고    scopus 로고
    • Effect of soy isoflavone protein and soy lecithin on endothelial function in healthy postmenopausal women
    • [CrossRef][PubMed]
    • Evans, M.; Njike, V.Y.; Hoxley, M.; Pearson, M.; Katz, D.L. Effect of soy isoflavone protein and soy lecithin on endothelial function in healthy postmenopausal women. Menopause 2007, 14, 141-149. [CrossRef] [PubMed]
    • (2007) Menopause , vol.14 , pp. 141-149
    • Evans, M.1    Njike, V.Y.2    Hoxley, M.3    Pearson, M.4    Katz, D.L.5
  • 71
    • 0027752805 scopus 로고
    • The L-arginine-nitric oxide pathway
    • [PubMed]
    • Moncada, S.; Higgs, A. The L-arginine-nitric oxide pathway. N. Engl. J. Med. 1993, 329, 2002-2012. [PubMed]
    • (1993) N. Engl. J. Med , vol.329 , pp. 2002-2012
    • Moncada, S.1    Higgs, A.2
  • 72
    • 82555170266 scopus 로고    scopus 로고
    • Effect of oral L-arginine supplementation on blood pressure: A meta-analysis of randomized, double-blind, placebo-controlled trials
    • [CrossRef][PubMed]
    • Dong, J.-Y.; Qin, L.-Q.; Zhang, Z.; Zhao, Y.; Wang, J.; Arigoni, F.; Zhang, W. Effect of oral L-arginine supplementation on blood pressure: A meta-analysis of randomized, double-blind, placebo-controlled trials. Am. Heart J. 2011, 162, 959-965. [CrossRef] [PubMed]
    • (2011) Am. Heart J , vol.162 , pp. 959-965
    • Dong, J.-Y.1    Qin, L.-Q.2    Zhang, Z.3    Zhao, Y.4    Wang, J.5    Arigoni, F.6    Zhang, W.7
  • 73
    • 58149389277 scopus 로고    scopus 로고
    • Increase in fasting vascular endothelial function after short-term oral L-arginine is effective when baseline flow-mediated dilation is low: Meta-analysis of randomized controlled trials
    • [CrossRef][PubMed]
    • Bai, Y.; Sun, L.; Yang, T.; Sun, K.; Chen, J.; Hui, R. Increase in fasting vascular endothelial function after short-term oral L-arginine is effective when baseline flow-mediated dilation is low: Meta-analysis of randomized controlled trials. Am. J. Clin. Nutr. 2009, 89, 77-84. [CrossRef] [PubMed]
    • (2009) Am. J. Clin. Nutr , vol.89 , pp. 77-84
    • Bai, Y.1    Sun, L.2    Yang, T.3    Sun, K.4    Chen, J.5    Hui, R.6
  • 74
    • 80052991138 scopus 로고    scopus 로고
    • The antihypertensive effect of arginine
    • [CrossRef][PubMed]
    • Vasdev, S.; Gill, V. The antihypertensive effect of arginine. Int. J. Angiol. 2008, 17, 7-22. [CrossRef] [PubMed]
    • (2008) Int. J. Angiol , vol.17 , pp. 7-22
    • Vasdev, S.1    Gill, V.2
  • 75
    • 85016136636 scopus 로고    scopus 로고
    • United States Department of Agriculture Agricultural Research Service: USDA Food Composition Databases. Available online: https://ndb.nal.usda.gov/ndb/search/list (accessed on 1 March 2017).
    • USDA Food Composition Databases
  • 76
    • 0025423902 scopus 로고
    • Evaluation of protein digestibility-corrected amino acid score method for assessing protein quality of foods
    • [PubMed]
    • Sarwar, G.; McDonough, F.E. Evaluation of protein digestibility-corrected amino acid score method for assessing protein quality of foods. J. Assoc. Off. Anal. Chem. 1990, 73, 347-356. [PubMed]
    • (1990) J. Assoc. Off. Anal. Chem , vol.73 , pp. 347-356
    • Sarwar, G.1    McDonough, F.E.2
  • 77
    • 83055165704 scopus 로고    scopus 로고
    • Protein digestibility-corrected amino acid scores (PDCAAS) for soy protein isolates and concentrate: Criteria for evaluation
    • [CrossRef][PubMed]
    • Hughes, G.J.; Ryan, D.J.; Mukherjea, R.; Schasteen, C.S. Protein digestibility-corrected amino acid scores (PDCAAS) for soy protein isolates and concentrate: Criteria for evaluation. J. Agric. Food Chem. 2011, 59, 12707-12712. [CrossRef] [PubMed]
    • (2011) J. Agric. Food Chem , vol.59 , pp. 12707-12712
    • Hughes, G.J.1    Ryan, D.J.2    Mukherjea, R.3    Schasteen, C.S.4
  • 79
  • 81
    • 57649213676 scopus 로고    scopus 로고
    • Glycation of LDL in non-diabetic people: Small dense LDL is preferentially glycated both in vivo and in vitro
    • [CrossRef][PubMed]
    • Younis, N.; Charlton-Menys, V.; Sharma, R.; Soran, H.; Durrington, P.N. Glycation of LDL in non-diabetic people: Small dense LDL is preferentially glycated both in vivo and in vitro. Atherosclerosis 2009, 202, 162-168. [CrossRef] [PubMed]
    • (2009) Atherosclerosis , vol.202 , pp. 162-168
    • Younis, N.1    Charlton-Menys, V.2    Sharma, R.3    Soran, H.4    Durrington, P.N.5
  • 82
    • 79954426590 scopus 로고    scopus 로고
    • Genistein reduces hyperglycemia and islet cell loss in a high-dosage manner in rats with alloxan-induced pancreatic damage
    • [CrossRef][PubMed]
    • Yang, W.; Wang, S.; Li, L.; Liang, Z.; Wang, L. Genistein reduces hyperglycemia and islet cell loss in a high-dosage manner in rats with alloxan-induced pancreatic damage. Pancreas 2011, 40, 396-402. [CrossRef] [PubMed]
    • (2011) Pancreas , vol.40 , pp. 396-402
    • Yang, W.1    Wang, S.2    Li, L.3    Liang, Z.4    Wang, L.5
  • 83
    • 84860485800 scopus 로고    scopus 로고
    • Genistein ameliorates hyperglycemia in a mouse model of nongenetic type 2 diabetes. Appl. Physiol. Nutr
    • [CrossRef][PubMed]
    • Fu, Z.; Gilbert, E.R.; Pfeiffer, L.; Zhang, Y.; Fu, Y.; Liu, D. Genistein ameliorates hyperglycemia in a mouse model of nongenetic type 2 diabetes. Appl. Physiol. Nutr. Metab. 2012, 37, 480-488. [CrossRef] [PubMed]
    • (2012) Metab , vol.37 , pp. 480-488
    • Fu, Z.1    Gilbert, E.R.2    Pfeiffer, L.3    Zhang, Y.4    Fu, Y.5    Liu, D.6
  • 84
    • 84855611272 scopus 로고    scopus 로고
    • Antihyperglycemic effect of biochanin A, a soy isoflavone, on streptozotocin-diabetic rats
    • [CrossRef][PubMed]
    • Harini, R.; Ezhumalai, M.; Pugalendi, K.V. Antihyperglycemic effect of biochanin A, a soy isoflavone, on streptozotocin-diabetic rats. Eur. J. Pharmacol. 2012, 676, 89-94. [CrossRef] [PubMed]
    • (2012) Eur. J. Pharmacol , vol.676 , pp. 89-94
    • Harini, R.1    Ezhumalai, M.2    Pugalendi, K.V.3
  • 85
    • 84873384928 scopus 로고    scopus 로고
    • Anti-diabetic functions of soy isoflavone genistein: Mechanisms underlying effects on pancreatic β-cell function
    • [CrossRef][PubMed]
    • Gilbert, E.R.; Liu, D. Anti-diabetic functions of soy isoflavone genistein: Mechanisms underlying effects on pancreatic β-cell function. Food Funct. 2013, 4, 200-212. [CrossRef] [PubMed]
    • (2013) Food Funct , vol.4 , pp. 200-212
    • Gilbert, E.R.1    Liu, D.2
  • 86
    • 84872781682 scopus 로고    scopus 로고
    • Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hypertension (angiotensin I converting enzyme) in vitro
    • [CrossRef][PubMed]
    • Ademiluyi, A.O.; Oboh, G. Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hypertension (angiotensin I converting enzyme) in vitro. Exp. Toxicol. Pathol. 2013, 65, 305-309. [CrossRef] [PubMed]
    • (2013) Exp. Toxicol. Pathol , vol.65 , pp. 305-309
    • Ademiluyi, A.O.1    Oboh, G.2
  • 88
    • 34948816560 scopus 로고    scopus 로고
    • Soy isoflavone supplementation and fasting serum glucose and lipid profile among postmenopausal Chinese women: A double-blind, randomized, placebo-controlled trial
    • [CrossRef][PubMed]
    • Ho, S.C.; Chen, Y.M.; Ho, S.S.; Woo, J.L. Soy isoflavone supplementation and fasting serum glucose and lipid profile among postmenopausal Chinese women: A double-blind, randomized, placebo-controlled trial. Menopause 2007, 14, 905-912. [CrossRef] [PubMed]
    • (2007) Menopause , vol.14 , pp. 905-912
    • Ho, S.C.1    Chen, Y.M.2    Ho, S.S.3    Woo, J.L.4
  • 89
    • 34547742675 scopus 로고    scopus 로고
    • Effects of the phytoestrogen genistein on some predictors of cardiovascular risk in osteopenic, postmenopausal women: A two-year randomized, double-blind, placebo-controlled study
    • [CrossRef][PubMed]
    • Atteritano, M.; Marini, H.; Minutoli, L.; Polito, F.; Bitto, A.; Altavilla, D.; Mazzaferro, S.; D’Anna, R.; Cannata, M.L.; Gaudio, A., et al. Effects of the phytoestrogen genistein on some predictors of cardiovascular risk in osteopenic, postmenopausal women: A two-year randomized, double-blind, placebo-controlled study. J. Clin. Endocrinol. Metab. 2007, 92, 3068-3075. [CrossRef] [PubMed]
    • (2007) J. Clin. Endocrinol. Metab , vol.92 , pp. 3068-3075
    • Atteritano, M.1    Marini, H.2    Minutoli, L.3    Polito, F.4    Bitto, A.5    Altavilla, D.6    Mazzaferro, S.7    D’Anna, R.8    Cannata, M.L.9    Gaudio, A.10
  • 90
    • 77951954720 scopus 로고    scopus 로고
    • Effects of soy protein and isoflavones on glycemic control and insulin sensitivity: A 6-month, randomized, placebo-controlled trial in postmenopausal Chinese women with prediabetes or untreated early diabetes
    • [CrossRef][PubMed]
    • Liu, Z.M.; Chen, Y.M.; Ho, S.C.; Ho, Y.P.; Woo, J. Effects of soy protein and isoflavones on glycemic control and insulin sensitivity: A 6-month, randomized, placebo-controlled trial in postmenopausal Chinese women with prediabetes or untreated early diabetes. Am. J. Clin. Nutr. 2010, 91, 1394-1401. [CrossRef] [PubMed]
    • (2010) Am. J. Clin. Nutr , vol.91 , pp. 1394-1401
    • Liu, Z.M.1    Chen, Y.M.2    Ho, S.C.3    Ho, Y.P.4    Woo, J.5
  • 91
    • 84922706350 scopus 로고    scopus 로고
    • Daidzein and genistein fail to improve glycemic control and insulin sensitivity in Chinese women with impaired glucose regulation: A double-blind, randomized, placebo-controlled trial
    • [CrossRef][PubMed]
    • Ye, Y.B.; Chen, A.L.; Lu, W.; Zhuo, S.Y.; Liu, J.; Guan, J.H.; Deng, W.P.; Fang, S.; Li, Y.B.; Chen, Y.M. Daidzein and genistein fail to improve glycemic control and insulin sensitivity in Chinese women with impaired glucose regulation: A double-blind, randomized, placebo-controlled trial. Mol. Nutr. Food Res. 2015, 59, 240-249. [CrossRef] [PubMed]
    • (2015) Mol. Nutr. Food Res , vol.59 , pp. 240-249
    • Ye, Y.B.1    Chen, A.L.2    Lu, W.3    Zhuo, S.Y.4    Liu, J.5    Guan, J.H.6    Deng, W.P.7    Fang, S.8    Li, Y.B.9    Chen, Y.M.10
  • 92
    • 77957713208 scopus 로고    scopus 로고
    • Effects of soy isoflavones and genistein on glucose metabolism in perimenopausal and postmenopausal non-Asian women: A meta-analysis of randomized controlled trials
    • [CrossRef][PubMed]
    • Ricci, E.; Cipriani, S.; Chiaffarino, F.; Malvezzi, M.; Parazzini, F. Effects of soy isoflavones and genistein on glucose metabolism in perimenopausal and postmenopausal non-Asian women: A meta-analysis of randomized controlled trials. Menopause 2010, 17, 1080-1086. [CrossRef] [PubMed]
    • (2010) Menopause , vol.17 , pp. 1080-1086
    • Ricci, E.1    Cipriani, S.2    Chiaffarino, F.3    Malvezzi, M.4    Parazzini, F.5
  • 93
    • 85027936140 scopus 로고    scopus 로고
    • Soy isoflavones and glucose metabolism in menopausal women: A systematic review and meta-analysis of randomized controlled trials
    • [CrossRef][PubMed]
    • Fang, K.; Dong, H.; Wang, D.; Gong, J.; Huang, W.; Lu, F. Soy isoflavones and glucose metabolism in menopausal women: A systematic review and meta-analysis of randomized controlled trials. Mol. Nutr. Food Res. 2016, 60, 1602-1614. [CrossRef] [PubMed]
    • (2016) Mol. Nutr. Food Res , vol.60 , pp. 1602-1614
    • Fang, K.1    Dong, H.2    Wang, D.3    Gong, J.4    Huang, W.5    Lu, F.6
  • 94
    • 84961250505 scopus 로고    scopus 로고
    • Soy protein supplementation reduces clinical indices in type 2 diabetes and metabolic syndrome
    • [CrossRef][PubMed]
    • Zhang, X.; Zhang, Y.; Chi, M. Soy protein supplementation reduces clinical indices in type 2 diabetes and metabolic syndrome. Yonsei Med. J. 2016, 57, 681-689. [CrossRef] [PubMed]
    • (2016) Yonsei Med. J , vol.57 , pp. 681-689
    • Zhang, X.1    Zhang, Y.2    Chi, M.3
  • 95
    • 79955381099 scopus 로고    scopus 로고
    • Effects of soy intake on glycemic control: A meta-analysis of randomized controlled trials
    • [CrossRef][PubMed]
    • Liu, Z.M.; Chen, Y.M.; Ho, S.C. Effects of soy intake on glycemic control: A meta-analysis of randomized controlled trials. Am. J. Clin. Nutr. 2011, 93, 1092-1101. [CrossRef] [PubMed]
    • (2011) Am. J. Clin. Nutr , vol.93 , pp. 1092-1101
    • Liu, Z.M.1    Chen, Y.M.2    Ho, S.C.3
  • 96
    • 84856428593 scopus 로고    scopus 로고
    • Evaluation of the Oxidative Stress and Glycemic Control Status in Response to Soy in OlderWomen with the Metabolic Syndrome
    • Bakhtiary, A.; Yassin, Z.; Hanachi, P.; Rahmat, A.; Ahmad, Z.; Halalkhor, S.; Firouzjahi, A.R. Evaluation of the Oxidative Stress and Glycemic Control Status in Response to Soy in OlderWomen with the Metabolic Syndrome. Iran. Red Crescent Med. J. 2011, 13, 795-804.
    • (2011) Iran. Red Crescent Med. J , vol.13 , pp. 795-804
    • Bakhtiary, A.1    Yassin, Z.2    Hanachi, P.3    Rahmat, A.4    Ahmad, Z.5    Halalkhor, S.6    Firouzjahi, A.R.7
  • 97
    • 33847772975 scopus 로고    scopus 로고
    • Soy inclusion in the diet improves features of the metabolic syndrome: A randomized crossover study in postmenopausal
    • [PubMed]
    • Azadbakht, L.; Kimiagar, M.; Mehrabi, Y.; Esmaillzadeh, A.; Padyab, M.; Hu, F.B.; Willett, W.C. Soy inclusion in the diet improves features of the metabolic syndrome: A randomized crossover study in postmenopausal. Am. J. Clin. Nutr. 2007, 85, 735-741. [PubMed]
    • (2007) Am. J. Clin. Nutr , vol.85 , pp. 735-741
    • Azadbakht, L.1    Kimiagar, M.2    Mehrabi, Y.3    Esmaillzadeh, A.4    Padyab, M.5    Hu, F.B.6    Willett, W.C.7
  • 98
    • 84868655606 scopus 로고    scopus 로고
    • Effects of a soybean nutrition bar on the postprandial blood glucose and lipid levels in patients with diabetes mellitus
    • [CrossRef][PubMed]
    • Urita, Y.; Noda, T.; Watanabe, D.; Iwashita, S.O.H.; Hamada, K.; Sugimoto, M. Effects of a soybean nutrition bar on the postprandial blood glucose and lipid levels in patients with diabetes mellitus. Int. J. Food Sci. Nutr. 2012, 63, 921-929. [CrossRef] [PubMed]
    • (2012) Int. J. Food Sci. Nutr , vol.63 , pp. 921-929
    • Urita, Y.1    Noda, T.2    Watanabe, D.3    Iwashita, S.O.H.4    Hamada, K.5    Sugimoto, M.6
  • 99
    • 77951429071 scopus 로고    scopus 로고
    • Effects of cake made from whole soy powder on postprandial blood glucose and insulin levels in human subjects
    • [CrossRef][PubMed]
    • Oku, T.; Nakamura, M.; Takasugi, A. Effects of cake made from whole soy powder on postprandial blood glucose and insulin levels in human subjects. Int. J. Food Sci. Nutr. 2009, 60, 224-231. [CrossRef] [PubMed]
    • (2009) Int. J. Food Sci. Nutr , vol.60 , pp. 224-231
    • Oku, T.1    Nakamura, M.2    Takasugi, A.3
  • 100
    • 85004008254 scopus 로고    scopus 로고
    • The physicochemical properties, in vitro binding capacities and in vivo hypocholesterolemic activity of soluble dietary fiber extracted from soy hulls
    • [CrossRef][PubMed]
    • Liu, C.; Lin, X.L.; Wan, Z.; Zou, Y.; Cheng, F.F.; Yang, X.Q. The physicochemical properties, in vitro binding capacities and in vivo hypocholesterolemic activity of soluble dietary fiber extracted from soy hulls. Food Funct. 2016, 7, 4830-4840. [CrossRef] [PubMed]
    • (2016) Food Funct , vol.7 , pp. 4830-4840
    • Liu, C.1    Lin, X.L.2    Wan, Z.3    Zou, Y.4    Cheng, F.F.5    Yang, X.Q.6
  • 101
    • 84897118166 scopus 로고    scopus 로고
    • Effects of soy-soluble fiber and flaxseed gum on the glycemic and insulinemic responses to glucose solutions and dairy products in healthy adult males
    • [CrossRef][PubMed]
    • Au, M.M.C.; Goff, D.; Kisch, J.A.; Coulson, A.; Wright, A.J. Effects of soy-soluble fiber and flaxseed gum on the glycemic and insulinemic responses to glucose solutions and dairy products in healthy adult males. J. Am. Coll. Nutr. 2013, 32, 98-110. [CrossRef] [PubMed]
    • (2013) J. Am. Coll. Nutr , vol.32 , pp. 98-110
    • Au, M.M.C.1    Goff, D.2    Kisch, J.A.3    Coulson, A.4    Wright, A.J.5
  • 102
    • 84941022986 scopus 로고    scopus 로고
    • Soya products and serum lipids: A meta-analysis of randomised controlled trials
    • [CrossRef][PubMed]
    • Tokede, O.A.; Onabanjo, T.A.; Yansane, A.; Gaziano, J.M.; Djoussé, L. Soya products and serum lipids: A meta-analysis of randomised controlled trials. Br. J. Nutr. 2015, 114, 831-943. [CrossRef] [PubMed]
    • (2015) Br. J. Nutr , vol.114 , pp. 831-943
    • Tokede, O.A.1    Onabanjo, T.A.2    Yansane, A.3    Gaziano, J.M.4    Djoussé, L.5
  • 103
    • 33846066888 scopus 로고    scopus 로고
    • Estrogen signaling multiple pathways to impact gene transcription
    • [CrossRef]
    • Marino, M.; Galluzzo, P.; Ascenzi, P. Estrogen signaling multiple pathways to impact gene transcription. Curr. Genom. 2006, 7, 497-508. [CrossRef]
    • (2006) Curr. Genom , vol.7 , pp. 497-508
    • Marino, M.1    Galluzzo, P.2    Ascenzi, P.3
  • 104
    • 20144375350 scopus 로고    scopus 로고
    • Molecular mechanisms of action of the soy isoflavones includes activation of promiscuous nuclear receptors. A review
    • [CrossRef][PubMed]
    • Ricketts, M.-L.; Moore, D.D.; Banz, W.J.; Mezei, O.; Shay, N.F. Molecular mechanisms of action of the soy isoflavones includes activation of promiscuous nuclear receptors. A review. J. Nutr. Biochem. 2005, 16, 321-330. [CrossRef] [PubMed]
    • (2005) J. Nutr. Biochem , vol.16 , pp. 321-330
    • Ricketts, M.-L.1    Moore, D.D.2    Banz, W.J.3    Mezei, O.4    Shay, N.F.5
  • 105
    • 84987788547 scopus 로고    scopus 로고
    • Isoflavone supplementation in postmenopausal women does not affect leukocyte LDL receptor and scavenger receptor CD36 expression: A double-blind, randomized, placebo-controlled trial
    • [CrossRef][PubMed]
    • Engelbert, A.K.; Soukup, S.T.; Roth, A.; Hoffmann, N.; Graf, D.; Watzl, B.; Kulling, S.E.; Bub, A. Isoflavone supplementation in postmenopausal women does not affect leukocyte LDL receptor and scavenger receptor CD36 expression: A double-blind, randomized, placebo-controlled trial. Mol. Nutr. Food Res. 2016, 60, 2008-2019. [CrossRef] [PubMed]
    • (2016) Mol. Nutr. Food Res , vol.60 , pp. 2008-2019
    • Engelbert, A.K.1    Soukup, S.T.2    Roth, A.3    Hoffmann, N.4    Graf, D.5    Watzl, B.6    Kulling, S.E.7    Bub, A.8
  • 106
    • 0842345433 scopus 로고    scopus 로고
    • Effect of circulating forms of soy isoflavones on the oxidation of low density lipoprotein
    • [CrossRef][PubMed]
    • Turner, R.; Baron, T.; Wolffram, S.; Minihane, A.M.; Cassidy, A.; Rimbach, G.; Weinberg, P.D. Effect of circulating forms of soy isoflavones on the oxidation of low density lipoprotein. Free Radic. Res. 2004, 38, 209-216. [CrossRef] [PubMed]
    • (2004) Free Radic. Res , vol.38 , pp. 209-216
    • Turner, R.1    Baron, T.2    Wolffram, S.3    Minihane, A.M.4    Cassidy, A.5    Rimbach, G.6    Weinberg, P.D.7
  • 107
    • 84888227781 scopus 로고    scopus 로고
    • Dietary supplementation with soy isoflavones or replacement with soy proteins prevents hepatic lipid droplet accumulation and alters expression of genes involved in lipid metabolism in rats
    • [CrossRef][PubMed]
    • Xiao, C.W.; Wood, C.M.; Weber, D.; Aziz, S.A.; Mehta, R.; Griffin, P.; Cockell, K.A. Dietary supplementation with soy isoflavones or replacement with soy proteins prevents hepatic lipid droplet accumulation and alters expression of genes involved in lipid metabolism in rats. Genes Nutr. 2014, 9, 373. [CrossRef] [PubMed]
    • (2014) Genes Nutr , vol.9 , pp. 373
    • Xiao, C.W.1    Wood, C.M.2    Weber, D.3    Aziz, S.A.4    Mehta, R.5    Griffin, P.6    Cockell, K.A.7
  • 108
    • 84916882961 scopus 로고    scopus 로고
    • Isoflavone and protein constituents of lactic acid-fermented soy milk combine to prevent dyslipidemia in rats fed a high cholesterol diet
    • [CrossRef][PubMed]
    • Kobayashi, M.; Egusa, S.; Fukuda, M. Isoflavone and protein constituents of lactic acid-fermented soy milk combine to prevent dyslipidemia in rats fed a high cholesterol diet. Nutrients 2014, 6, 5704-5723. [CrossRef] [PubMed]
    • (2014) Nutrients , vol.6 , pp. 5704-5723
    • Kobayashi, M.1    Egusa, S.2    Fukuda, M.3
  • 109
    • 84863344309 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of soy products consumption in patients with type 2 diabetes mellitus
    • [PubMed]
    • Yang, B.; Chen, Y.; Xu, T.C.; Yu, Y.H.; Huang, T.; Hu, X.J.; Li, D. Systematic review and meta-analysis of soy products consumption in patients with type 2 diabetes mellitus. Asia Pac. J. Clin. Nutr. 2011, 20, 593-602. [PubMed]
    • (2011) Asia Pac. J. Clin. Nutr , vol.20 , pp. 593-602
    • Yang, B.1    Chen, Y.2    Xu, T.C.3    Yu, Y.H.4    Huang, T.5    Hu, X.J.6    Li, D.7
  • 110
    • 84879363603 scopus 로고    scopus 로고
    • CZolesterol-lowering activity of soy-derived glyceollins in the golden Syrian hamster model
    • [CrossRef][PubMed]
    • Huang, H.; Xie, Z.; Boue, S.M.; Bhatnagar, D.; Yokoyama, W.; Yu, L.; Wang, T.T.Y. CZolesterol-lowering activity of soy-derived glyceollins in the golden Syrian hamster model. J. Agric. Food Chem. 2013, 61, 5772-5782. [CrossRef] [PubMed]
    • (2013) J. Agric. Food Chem , vol.61 , pp. 5772-5782
    • Huang, H.1    Xie, Z.2    Boue, S.M.3    Bhatnagar, D.4    Yokoyama, W.5    Yu, L.6    Wang, T.T.Y.7
  • 111
    • 84979713797 scopus 로고    scopus 로고
    • Okara, a by-product of tofu manufacturing, modifies triglyceride metabolism at the intestinal and hepatic levels
    • [CrossRef][PubMed]
    • Nagata, Y.; Yamasaki, S.; Torisu, N.; Suzuki, T.; Shimamoto, S.; Tamaru, S.; Tanaka, K. Okara, a by-product of tofu manufacturing, modifies triglyceride metabolism at the intestinal and hepatic levels. J. Nutr. Sci. Vitaminol. 2016, 62, 162-169. [CrossRef] [PubMed]
    • (2016) J. Nutr. Sci. Vitaminol , vol.62 , pp. 162-169
    • Nagata, Y.1    Yamasaki, S.2    Torisu, N.3    Suzuki, T.4    Shimamoto, S.5    Tamaru, S.6    Tanaka, K.7
  • 112
    • 84874011234 scopus 로고    scopus 로고
    • Fat lowers fat: Purified phospholipids as emerging therapies for dyslipidemia
    • [CrossRef][PubMed]
    • Sahebkar, A. Fat lowers fat: Purified phospholipids as emerging therapies for dyslipidemia. Biochem. Biophys. Acta-Mol. Cell Biol. Lipids 2013, 1831, 887-893. [CrossRef] [PubMed]
    • (2013) Biochem. Biophys. Acta-Mol. Cell Biol. Lipids , vol.1831 , pp. 887-893
    • Sahebkar, A.1
  • 113
    • 0022409492 scopus 로고
    • The Effects of oral soybean phospholipid on serum total cholesterol, plasma triglyceride, and serum high-density lipoprotein cholesterol concentrations in hyperlipidemia
    • [CrossRef][PubMed]
    • Ovesen, L.; Ebbesen, K.; Olesen, E.S. The Effects of oral soybean phospholipid on serum total cholesterol, plasma triglyceride, and serum high-density lipoprotein cholesterol concentrations in hyperlipidemia. J. Parent. Enter. Nutr. 1985, 9, 716-719. [CrossRef] [PubMed]
    • (1985) J. Parent. Enter. Nutr , vol.9 , pp. 716-719
    • Ovesen, L.1    Ebbesen, K.2    Olesen, E.S.3
  • 115
    • 15244353871 scopus 로고    scopus 로고
    • Double-blind placebo-controlled clinical trial compares the cholesterol-lowering effects of two different soy protein preparations in hypercholesterolemic subjects
    • [CrossRef][PubMed]
    • Høie, L.H.; Morgenstern, E.C.; Gruenwald, J.; Graubaum, H.J.; Busch, R.; Lüder, W.; Zunft, H.J. A double-blind placebo-controlled clinical trial compares the cholesterol-lowering effects of two different soy protein preparations in hypercholesterolemic subjects. Eur. J. Nutr. 2005, 44, 65-71. [CrossRef] [PubMed]
    • (2005) Eur. J. Nutr , vol.44 , pp. 65-71
    • Høie, L.H.1    Morgenstern, E.C.2    Gruenwald, J.3    Graubaum, H.J.4    Busch, R.5    Lüder, W.6    Zunft, H.7
  • 116
    • 31944435514 scopus 로고    scopus 로고
    • Effect of a low glycemic index diet with soy protein and phytosterols on CVD risk factors in postmenopausal women
    • [CrossRef][PubMed]
    • Lukaczer, D.; Liska, D.J.; Lerman, R.H.; Darland, G.; Schilz, B.; Tripp, M.; Bland, J.S. Effect of a low glycemic index diet with soy protein and phytosterols on CVD risk factors in postmenopausal women. Nutrition 2006, 22, 104-113. [CrossRef] [PubMed]
    • (2006) Nutrition , vol.22 , pp. 104-113
    • Lukaczer, D.1    Liska, D.J.2    Lerman, R.H.3    Darland, G.4    Schilz, B.5    Tripp, M.6    Bland, J.S.7
  • 117
    • 84978516361 scopus 로고    scopus 로고
    • Soy milk powder supplemented with phytosterol esters reduced serum cholesterol level in hypercholesterolemia independently of lipoprotein E genotype: A random clinical placebo-controlled trial
    • [CrossRef][PubMed]
    • Dong, S.; Zhang, R.; Ji, Y.; Hao, J.Y.; Ma, W.W.; Chen, X.D.; Xiao, R.; Yu, H.L. Soy milk powder supplemented with phytosterol esters reduced serum cholesterol level in hypercholesterolemia independently of lipoprotein E genotype: A random clinical placebo-controlled trial. Nutr. Res. 2016, 36, 879-884. [CrossRef] [PubMed]
    • (2016) Nutr. Res , vol.36 , pp. 879-884
    • Dong, S.1    Zhang, R.2    Ji, Y.3    Hao, J.Y.4    Ma, W.W.5    Chen, X.D.6    Xiao, R.7    Yu, H.L.8
  • 118
    • 84963846238 scopus 로고    scopus 로고
    • Krul, E.S. Soy protein compared with milk protein in a western diet increases gut microbial diversity and reduces serum lipids in golden Syrian hamsters
    • Butteiger, D.N.; Hibberd, A.A.; McGraw, N.J.; Napawan, N.; Hall-Porter, J.M.; Krul, E.S. Soy protein compared with milk protein in a western diet increases gut microbial diversity and reduces serum lipids in golden Syrian hamsters. J. Nutr. 2016, 146, 697-705.
    • (2016) J. Nutr , vol.146 , pp. 697-705
    • Butteiger, D.N.1    Hibberd, A.A.2    McGraw, N.J.3    Napawan, N.4    Hall-Porter, J.M.5
  • 119
    • 33644872836 scopus 로고    scopus 로고
    • Inflammation and cardiovascular disease mechanisms
    • [PubMed]
    • Libby, P. Inflammation and cardiovascular disease mechanisms. Am. J. Clin. Nutr. 2006, 83, 456S-460S. [PubMed]
    • (2006) Am. J. Clin. Nutr , vol.83 , pp. 456S-460S
    • Libby, P.1
  • 120
    • 84939988250 scopus 로고    scopus 로고
    • Protective effects of genistein in homocysteine-induced endothelial cell inflammatory injury
    • [CrossRef][PubMed]
    • Han, S.; Wu, H.; Li, W.; Gao, P. Protective effects of genistein in homocysteine-induced endothelial cell inflammatory injury. Mol. Cell. Biochem. 2015, 403, 43-49. [CrossRef] [PubMed]
    • (2015) Mol. Cell. Biochem , vol.403 , pp. 43-49
    • Han, S.1    Wu, H.2    Li, W.3    Gao, P.4
  • 122
    • 84960532923 scopus 로고    scopus 로고
    • The dietary isoflavone daidzein reduces expression of pro-inflammatory genes through PPARα/γ and JNK pathways in adipocyte and macrophage co-cultures
    • [CrossRef][PubMed]
    • Sakamoto, Y.; Kanatsu, J.; Toh, M.; Naka, A.; Kondo, K.; Iida, K. The dietary isoflavone daidzein reduces expression of pro-inflammatory genes through PPARα/γ and JNK pathways in adipocyte and macrophage co-cultures. PLoS ONE 2016, 11, e0149676. [CrossRef] [PubMed]
    • (2016) Plos ONE , vol.11
    • Sakamoto, Y.1    Kanatsu, J.2    Toh, M.3    Naka, A.4    Kondo, K.5    Iida, K.6
  • 123
    • 84946124340 scopus 로고    scopus 로고
    • Consumption of soy isoflavone enriched bread in men with prostate cancer is associated with reduced proinflammatory cytokines and immunosuppressive cells
    • [CrossRef][PubMed]
    • Lesinski, G.B.; Reville, P.K.; Mace, T.A.; Young, G.S.; Ahn-Jarvis, J.; Thomas-Ahner, J.; Vodovotz, Y.; Ameen, Z.; Grainger, E.; Riedl, K., et al. Consumption of soy isoflavone enriched bread in men with prostate cancer is associated with reduced proinflammatory cytokines and immunosuppressive cells. Cancer Prev. Res. 2015, 8, 1036-1044. [CrossRef] [PubMed]
    • (2015) Cancer Prev. Res , vol.8 , pp. 1036-1044
    • Lesinski, G.B.1    Reville, P.K.2    Mace, T.A.3    Young, G.S.4    Ahn-Jarvis, J.5    Thomas-Ahner, J.6    Vodovotz, Y.7    Ameen, Z.8    Grainger, E.9    Riedl, K.10
  • 124
    • 84955673724 scopus 로고    scopus 로고
    • Dietary isoflavone intake is associated with evoked responses to inflammatory cardiometabolic stimuli and improved glucose homeostasis in healthy volunteers
    • [CrossRef][PubMed]
    • Ferguson, J.F.; Ryan, M.F.; Gibney, E.R.; Brennan, L.; Roche, H.M.; Reilly, M.P. Dietary isoflavone intake is associated with evoked responses to inflammatory cardiometabolic stimuli and improved glucose homeostasis in healthy volunteers. Nutr. Metab. Cardiovasc. Dis. 2014, 24, 996-1003. [CrossRef] [PubMed]
    • (2014) Nutr. Metab. Cardiovasc. Dis , vol.24 , pp. 996-1003
    • Ferguson, J.F.1    Ryan, M.F.2    Gibney, E.R.3    Brennan, L.4    Roche, H.M.5    Reilly, M.P.6
  • 125
    • 79951727223 scopus 로고    scopus 로고
    • Soy isoflavones, diet and physical exercise modify serum cytokines in healthy obese postmenopausal women
    • [CrossRef][PubMed]
    • Llaneza, P.; González, C.; Fernandez-Iñarrea, J.; Alonso, A.; Diaz, F.; Arnott, I.; Ferrer-Barriendos, J. Soy isoflavones, diet and physical exercise modify serum cytokines in healthy obese postmenopausal women. Phytomedicine 2011, 18, 245-250. [CrossRef] [PubMed]
    • (2011) Phytomedicine , vol.18 , pp. 245-250
    • Llaneza, P.1    González, C.2    Fernandez-Iñarrea, J.3    Alonso, A.4    Diaz, F.5    Arnott, I.6    Ferrer-Barriendos, J.7
  • 126
    • 48649098937 scopus 로고    scopus 로고
    • Soy protein intake, cardiorenal indices, and C-reactive protein in type 2 diabetes
    • [CrossRef][PubMed]
    • Azadbakht, L.; Atabak, S.; Esmaillzadeh, A. Soy protein intake, cardiorenal indices, and C-reactive protein in type 2 diabetes. Diabetes Care 2008, 31, 648-654. [CrossRef] [PubMed]
    • (2008) Diabetes Care , vol.31 , pp. 648-654
    • Azadbakht, L.1    Atabak, S.2    Esmaillzadeh, A.3
  • 127
    • 84928126089 scopus 로고    scopus 로고
    • Intradialytic protein supplementation reduces inflammation and improves physical function in maintenance hemodialysis patients
    • [CrossRef][PubMed]
    • Tomayko, E.J.; Kistler, B.M.; Fitschen, P.J.; Wilund, K.R. Intradialytic protein supplementation reduces inflammation and improves physical function in maintenance hemodialysis patients. J. Ren. Nutr. 2015, 25, 276-283. [CrossRef] [PubMed]
    • (2015) J. Ren. Nutr , vol.25 , pp. 276-283
    • Tomayko, E.J.1    Kistler, B.M.2    Fitschen, P.J.3    Wilund, K.R.4
  • 128
    • 84922814258 scopus 로고    scopus 로고
    • Soy provides modest benefits on endothelial function without affecting inflammatory biomarkers in adults at cardiometabolic risk
    • [CrossRef][PubMed]
    • Reverri, E.J.; LaSalle, C.D.; Franke, A.A.; Steinberg, F.M. Soy provides modest benefits on endothelial function without affecting inflammatory biomarkers in adults at cardiometabolic risk. Mol. Nutr. Food Res. 2015, 59, 323-332. [CrossRef] [PubMed]
    • (2015) Mol. Nutr. Food Res , vol.59 , pp. 323-332
    • Reverri, E.J.1    Lasalle, C.D.2    Franke, A.A.3    Steinberg, F.M.4
  • 129
    • 0024948772 scopus 로고
    • Effects of acute protein loads of different sources on renal function of patients with diabetic nephropathy. Tohoku
    • [CrossRef][PubMed]
    • Nakamura, H.; Takasawa, M.; Kashara, S.; Tsuda, A.; Momotsu, T.; Ito, S.; Shibata, A. Effects of acute protein loads of different sources on renal function of patients with diabetic nephropathy. Tohoku J. Exp. Med. 1989, 159, 153-162. [CrossRef] [PubMed]
    • (1989) J. Exp. Med , vol.159 , pp. 153-162
    • Nakamura, H.1    Takasawa, M.2    Kashara, S.3    Tsuda, A.4    Momotsu, T.5    Ito, S.6    Shibata, A.7
  • 130
    • 0035890259 scopus 로고    scopus 로고
    • Dietary glycine inhibits activation of nuclear factor kappa B and prevents liver injury in hemorrhagic shock in the rat
    • [CrossRef]
    • Mauriz, J.L.; Matilla, B.; Culebras, J.M.; Gonzalez, P.; Gonzalez-Gallego, J. Dietary glycine inhibits activation of nuclear factor kappa B and prevents liver injury in hemorrhagic shock in the rat. Free Radic. Biol. Med. 2001, 31, 1236-1244. [CrossRef]
    • (2001) Free Radic. Biol. Med , vol.31 , pp. 1236-1244
    • Mauriz, J.L.1    Matilla, B.2    Culebras, J.M.3    Gonzalez, P.4    Gonzalez-Gallego, J.5
  • 131
    • 84872271216 scopus 로고    scopus 로고
    • Obesity, systemic inflammation, and increased risk for cardiovascular disease and diabetes among adolescents: A need for screening tools to target interventions
    • [CrossRef][PubMed]
    • DeBoer, M.D. Obesity, systemic inflammation, and increased risk for cardiovascular disease and diabetes among adolescents: A need for screening tools to target interventions. Nutrition 2013, 29, 379-386. [CrossRef] [PubMed]
    • (2013) Nutrition , vol.29 , pp. 379-386
    • Deboer, M.D.1
  • 133
    • 4544241331 scopus 로고    scopus 로고
    • Oxidative damage precedes nitrative damage in adriamycin-induced cardiac mitochondrial injury
    • [PubMed]
    • Chaiswing, L.; Cole, M.P.; St. Clair D.K., Ittarat, W.; Szweda, L.I.; Oberley, T.D. Oxidative damage precedes nitrative damage in adriamycin-induced cardiac mitochondrial injury. Toxicol. Pathol. 2004, 32, 536-547. [PubMed]
    • (2004) Toxicol. Pathol , vol.32 , pp. 536-547
    • Chaiswing, L.1    Cole, M.P.2    St. Clair, D.K.3    Ittarat, W.4    Szweda, L.I.5    Oberley, T.D.6
  • 135
    • 84973547945 scopus 로고    scopus 로고
    • Soy Isoflavones regulate lipid metabolism through an AKT/mTORC1 pathway in diet-induced obesity (DIO) male rats
    • [CrossRef][PubMed]
    • Huang, C.; Pang, D.; Luo, Q.; Chen, X.; Gao, Q.; Shi, L.; Liu, W.; Zou, Y.; Li, L.; Chen, Z. Soy Isoflavones regulate lipid metabolism through an AKT/mTORC1 pathway in diet-induced obesity (DIO) male rats. Molecules 2016, 21, 586. [CrossRef] [PubMed]
    • (2016) Molecules , vol.21 , pp. 586
    • Huang, C.1    Pang, D.2    Luo, Q.3    Chen, X.4    Gao, Q.5    Shi, L.6    Liu, W.7    Zou, Y.8    Li, L.9    Chen, Z.10
  • 136
    • 84868358727 scopus 로고    scopus 로고
    • Soy isoflavones modulate adipokines and myokines to regulate lipid metabolism in adipose tissue, skeletal muscle and liver of male Huanjiang mini-pigs
    • [CrossRef][PubMed]
    • Yang, H.; Li, F.; Xiong, X.; Kong, X.; Zhang, B.; Yuan, X.; Fan, J.; Duan, Y.; Geng, M.; Li, L., et al. Soy isoflavones modulate adipokines and myokines to regulate lipid metabolism in adipose tissue, skeletal muscle and liver of male Huanjiang mini-pigs. Mol. Cell. Endocrinol. 2013, 365, 44-51. [CrossRef] [PubMed]
    • (2013) Mol. Cell. Endocrinol , vol.365 , pp. 44-51
    • Yang, H.1    Li, F.2    Xiong, X.3    Kong, X.4    Zhang, B.5    Yuan, X.6    Fan, J.7    Duan, Y.8    Geng, M.9    Li, L.10
  • 137
    • 84984799860 scopus 로고    scopus 로고
    • Phytochemicals in regulating fatty acid β-oxidation: Potential underlying mechanisms and their involvement in obesity and weight loss
    • [CrossRef][PubMed]
    • Rupasinghe, H.P.V.; Sekhon-Loodu, S.; Mantso, T.; Panayiotidis, M.I. Phytochemicals in regulating fatty acid β-oxidation: Potential underlying mechanisms and their involvement in obesity and weight loss. Pharmacol. Ther. 2016, 165, 153-163. [CrossRef] [PubMed]
    • (2016) Pharmacol. Ther , vol.165 , pp. 153-163
    • Rupasinghe, H.P.V.1    Sekhon-Loodu, S.2    Mantso, T.3    Panayiotidis, M.I.4
  • 138
    • 84942366210 scopus 로고    scopus 로고
    • Soy and the soy isoflavone genistein promote adipose tissue development in male mice on a low-fat diet
    • [CrossRef][PubMed]
    • Zanella, I.; Marrazzo, E.; Biasiotto, G.; Penza, M.; Romani, A.; Vignolini, P.; Caimi, L.; Di Lorenzo, D. Soy and the soy isoflavone genistein promote adipose tissue development in male mice on a low-fat diet. Eur. J. Nutr. 2015, 54, 1095-1107. [CrossRef] [PubMed]
    • (2015) Eur. J. Nutr , vol.54 , pp. 1095-1107
    • Zanella, I.1    Marrazzo, E.2    Biasiotto, G.3    Penza, M.4    Romani, A.5    Vignolini, P.6    Caimi, L.7    Di, L.D.8
  • 139
    • 84964240681 scopus 로고    scopus 로고
    • Soy isoflavones in nutritionally relevant amounts have varied nutrigenomic effects on adipose tissue
    • [CrossRef][PubMed]
    • Giordano, E.; Dávalos, A.; Crespo, M.C.; Tomé-Carneiro, J.; Gómez-Coronado, D.; ViZioli, F. Soy isoflavones in nutritionally relevant amounts have varied nutrigenomic effects on adipose tissue. Molecules 2015, 20, 2310-2322. [CrossRef] [PubMed]
    • (2015) Molecules , vol.20 , pp. 2310-2322
    • Giordano, E.1    Dávalos, A.2    Crespo, M.C.3    Tomé-Carneiro, J.4    Gómez-Coronado, D.5    Vizioli, F.6
  • 140
    • 84906987163 scopus 로고    scopus 로고
    • Ameliorative effects of Monascus pilosus-fermented black soybean (Glycine max L. Merrill) on high-fat diet-induced obesity
    • [CrossRef][PubMed]
    • Oh, H.-G.; Kang, Y.-R.; Lee, H.-Y.; Kim, J.-H.; Shin, E.-H.; Lee, B.-G.; Park, S.-H.; Moon, D.-I.; Kim, O.-J.; Lee, I.A., et al. Ameliorative effects of Monascus pilosus-fermented black soybean (Glycine max L. Merrill) on high-fat diet-induced obesity. J. Med. Food 2014, 17, 972-978. [CrossRef] [PubMed]
    • (2014) J. Med. Food , vol.17 , pp. 972-978
    • Oh, H.-G.1    Kang, Y.-R.2    Lee, H.-Y.3    Kim, J.-H.4    Shin, E.-H.5    Lee, B.-G.6    Park, S.-H.7    Moon, D.-I.8    Kim, O.-J.9    Lee, I.A.10
  • 141
    • 33646250884 scopus 로고    scopus 로고
    • Effects of isoflavone and exercise on BMD and fat mass in postmenopausal Japanese women: A 1-year randomized placebo-controlled trial
    • [CrossRef][PubMed]
    • Wu, J.; Oka, J.; Tabata, I.; Higuchi, M.; Toda, T.; Fuku, N.; Ezaki, J.; Sugiyama, F.; Uchiyama, S.; Yamada, K., et al. Effects of isoflavone and exercise on BMD and fat mass in postmenopausal Japanese women: A 1-year randomized placebo-controlled trial. J. Bone Miner. Res. 2006, 21, 780-789. [CrossRef] [PubMed]
    • (2006) J. Bone Miner. Res , vol.21 , pp. 780-789
    • Wu, J.1    Oka, J.2    Tabata, I.3    Higuchi, M.4    Toda, T.5    Fuku, N.6    Ezaki, J.7    Sugiyama, F.8    Uchiyama, S.9    Yamada, K.10
  • 142
    • 77952262219 scopus 로고    scopus 로고
    • Appetitive hormones, but not isoflavone tablets, influence overall and central adiposity in healthy postmenopausal women
    • [CrossRef][PubMed]
    • Matvienko, O.A.; Alekel, D.L.; Genschel, U.; Ritland, L.; Van Loan, M.D.; Koehler, K.J. Appetitive hormones, but not isoflavone tablets, influence overall and central adiposity in healthy postmenopausal women. Menopause 2010, 17, 594-601. [CrossRef] [PubMed]
    • (2010) Menopause , vol.17 , pp. 594-601
    • Matvienko, O.A.1    Alekel, D.L.2    Genschel, U.3    Ritland, L.4    van Loan, M.D.5    Koehler, K.J.6
  • 143
    • 84898009943 scopus 로고    scopus 로고
    • Obesity prevalence in relation to gut microbial environments capable of producing equol or O-desmethylangolensin from the isoflavone daidzein
    • [CrossRef][PubMed]
    • Frankenfeld, C.L.; Atkinson, C.; Wähälä, K.; Lampe, J.W. Obesity prevalence in relation to gut microbial environments capable of producing equol or O-desmethylangolensin from the isoflavone daidzein. Eur. J. Clin. Nutr. 2014, 68, 526-530. [CrossRef] [PubMed]
    • (2014) Eur. J. Clin. Nutr , vol.68 , pp. 526-530
    • Frankenfeld, C.L.1    Atkinson, C.2    Wähälä, K.3    Lampe, J.W.4
  • 144
    • 84903382544 scopus 로고    scopus 로고
    • Azadbakht, L. Effects of a novel therapeutic diet on liver enzymes and coagulating factors in patients with non-alcoholic fatty liver disease: A parallel randomized trial
    • [CrossRef][PubMed]
    • Kani, A.H.; Alavian, S.M.; Esmaillzadeh, A.; Adibi, P.; Azadbakht, L. Effects of a novel therapeutic diet on liver enzymes and coagulating factors in patients with non-alcoholic fatty liver disease: A parallel randomized trial. Nutrition 2014, 30, 814-821. [CrossRef] [PubMed]
    • (2014) Nutrition , vol.30 , pp. 814-821
    • Kani, A.H.1    Alavian, S.M.2    Esmaillzadeh, A.3    Adibi, P.4
  • 145
    • 85016142445 scopus 로고    scopus 로고
    • Comparison of the influences of soy-vs. Wheat-based supplements on weight loss in middle-aged subjects
    • [CrossRef]
    • Suga, Y.; Tanabe, K.; Kim, J.; Sato, H.; Iwashita, S.; Hamada, K.; Kuno, S. A comparison of the influences of soy-vs. wheat-based supplements on weight loss in middle-aged subjects. Int. J. Sport Health Sci. 2013, 11, 10-19. [CrossRef]
    • (2013) Int. J. Sport Health Sci , vol.11 , pp. 10-19
    • Suga, Y.1    Tanabe, K.2    Kim, J.3    Sato, H.4    Iwashita, S.5    Hamada, K.6    Kuno, S.A.7
  • 146
    • 84925538658 scopus 로고    scopus 로고
    • Effect of protein source during weight loss on body composition, cardiometabolic risk and physical performance in abdominally obese, older adults: A pilot feeding study
    • [CrossRef][PubMed]
    • Beavers, K.M.; Gordon, M.M.; Easter, L.; Beavers, D.P.; Hairston, K.G.; Nicklas, B.J.; Vitolins, M.Z. Effect of protein source during weight loss on body composition, cardiometabolic risk and physical performance in abdominally obese, older adults: A pilot feeding study. J. Nutr. Health Aging 2015, 19, 87-95. [CrossRef] [PubMed]
    • (2015) J. Nutr. Health Aging , vol.19 , pp. 87-95
    • Beavers, K.M.1    Gordon, M.M.2    Easter, L.3    Beavers, D.P.4    Hairston, K.G.5    Nicklas, B.J.6    Vitolins, M.Z.7
  • 147
    • 80052138394 scopus 로고    scopus 로고
    • Randomized, double-blind, controlled, comparative trial of formula food containing soy protein vs. Milk protein in visceral fat obesity
    • [PubMed]
    • Takahira, M.; Noda, K.; Fukushima, M.; Zhang, B.; Mitsutake, R.; Uehara, Y.; Ogawa, M.; Kakuma, T.; Saku, K. Randomized, double-blind, controlled, comparative trial of formula food containing soy protein vs. milk protein in visceral fat obesity. Circ. J. 2011, 75, 2235-2243. [PubMed]
    • (2011) Circ. J , vol.75 , pp. 2235-2243
    • Takahira, M.1    Noda, K.2    Fukushima, M.3    Zhang, B.4    Mitsutake, R.5    Uehara, Y.6    Ogawa, M.7    Kakuma, T.8    Saku, K.9
  • 149
    • 84866989200 scopus 로고    scopus 로고
    • Weight reduction effects of a black soy peptide supplement in overweight and obese subjects: Double blind, randomized, controlled study
    • [CrossRef][PubMed]
    • Kwak, J.H.; Ahn, C.W.; Park, S.H.; Jung, S.U.; Min, B.J.; Kim, O.Y.; Lee, J.H. Weight reduction effects of a black soy peptide supplement in overweight and obese subjects: Double blind, randomized, controlled study. Food Funct. 2012, 3, 1019-1024. [CrossRef] [PubMed]
    • (2012) Food Funct , vol.3 , pp. 1019-1024
    • Kwak, J.H.1    Ahn, C.W.2    Park, S.H.3    Jung, S.U.4    Min, B.J.5    Kim, O.Y.6    Lee, J.H.7
  • 150
    • 84897941003 scopus 로고    scopus 로고
    • The impact of a weight reduction program with and without meal-replacement on health related quality of life in middle-aged obese females
    • [CrossRef][PubMed]
    • Koohkan, S.; Schaffner, D.; Milliron, B.J.; Frey, I.; König, D.; Deibert, P.; Vitolins, M.; Berg, A. The impact of a weight reduction program with and without meal-replacement on health related quality of life in middle-aged obese females. BMC Womens Health 2014, 14, 45. [CrossRef] [PubMed]
    • (2014) BMC Womens Health , vol.14 , pp. 45
    • Koohkan, S.1    Schaffner, D.2    Milliron, B.J.3    Frey, I.4    König, D.5    Deibert, P.6    Vitolins, M.7    Berg, A.8
  • 151
  • 152
    • 84870917275 scopus 로고    scopus 로고
    • A comparison of satiety, glycemic index, and insulinemic index of wheat-derived soft pretzels with or without soy
    • [CrossRef][PubMed]
    • Simmons, A.L.; Miller, C.K.; Clinton, S.K.; Vodovot, Y. A comparison of satiety, glycemic index, and insulinemic index of wheat-derived soft pretzels with or without soy. Food Funct. 2011, 2, 678-683. [CrossRef] [PubMed]
    • (2011) Food Funct , vol.2 , pp. 678-683
    • Simmons, A.L.1    Miller, C.K.2    Clinton, S.K.3    Vodovot, Y.4
  • 153
    • 84929484491 scopus 로고    scopus 로고
    • Consuming beef vs. Soy protein has little effect on appetite, satiety, and food intake in healthy Adults
    • [CrossRef][PubMed]
    • Douglas, S.M.; Lasley, T.R.; Leidy, H.J. Consuming beef vs. soy protein has little effect on appetite, satiety, and food intake in healthy Adults. J. Nutr. 2015, 145, 1010-1016. [CrossRef] [PubMed]
    • (2015) J. Nutr , vol.145 , pp. 1010-1016
    • Douglas, S.M.1    Lasley, T.R.2    Leidy, H.J.3
  • 154
    • 84905395005 scopus 로고    scopus 로고
    • Appetite control and biomarkers of satiety with vegetarian (Soy) and meat-based high-protein diets for weight loss in obese men: A randomized crossover trial
    • [CrossRef][PubMed]
    • Neacsu, M.; Fyfe, C.; Horgan, G.; Johnstone, A.M. Appetite control and biomarkers of satiety with vegetarian (soy) and meat-based high-protein diets for weight loss in obese men: A randomized crossover trial. Am. J. Clin. Nutr. 2014, 100, 548-558. [CrossRef] [PubMed]
    • (2014) Am. J. Clin. Nutr , vol.100 , pp. 548-558
    • Neacsu, M.1    Fyfe, C.2    Horgan, G.3    Johnstone, A.M.4
  • 155
    • 84927675042 scopus 로고    scopus 로고
    • Whey protein preloads are more beneficial than soy protein preloads in regulating appetite, calorie intake, anthropometry, and body composition of overweight and obese men
    • [CrossRef][PubMed]
    • Tahavorgar, A.; Vafa, M.; Shidfar, F.; Gohari, M.; Heydari, I. Whey protein preloads are more beneficial than soy protein preloads in regulating appetite, calorie intake, anthropometry, and body composition of overweight and obese men. Nutr. Res. 2014, 34, 856-861. [CrossRef] [PubMed]
    • (2014) Nutr. Res , vol.34 , pp. 856-861
    • Tahavorgar, A.1    Vafa, M.2    Shidfar, F.3    Gohari, M.4    Heydari, I.5
  • 157
    • 84935427616 scopus 로고    scopus 로고
    • Consuming high-protein soy snacks affects appetite control, satiety, and diet quality in young people and influences select aspects of mood and cognition
    • [CrossRef][PubMed]
    • Leidy, H.J.; Todd, C.B.; Zino, A.Z.; Immel, J.E.; Mukherjea, R.; Shafer, R.S.; Ortinau, L.C.; Braun, M. Consuming high-protein soy snacks affects appetite control, satiety, and diet quality in young people and influences select aspects of mood and cognition. J. Nutr. 2015, 145, 1614-1622. [CrossRef] [PubMed]
    • (2015) J. Nutr , vol.145 , pp. 1614-1622
    • Leidy, H.J.1    Todd, C.B.2    Zino, A.Z.3    Immel, J.E.4    Mukherjea, R.5    Shafer, R.S.6    Ortinau, L.C.7    Braun, M.8
  • 158
    • 83355169634 scopus 로고    scopus 로고
    • Fuel selection and appetite-regulating hormones after intake of a soy protein-based meal replacement
    • [CrossRef][PubMed]
    • König, D.; Muser, K.; Berg, A.; Deibert, P. Fuel selection and appetite-regulating hormones after intake of a soy protein-based meal replacement. Nutrition 2012, 28, 35-39. [CrossRef] [PubMed]
    • (2012) Nutrition , vol.28 , pp. 35-39
    • König, D.1    Muser, K.2    Berg, A.3    Deibert, P.4
  • 159
    • 44949211455 scopus 로고    scopus 로고
    • Effects of diets high in whey, soy, red meat and milk protein on body weight maintenance in diet-induced obesity in mice
    • [CrossRef]
    • Huang, X.F.; Liu, H.; Rahardjo, G.L.; Mclennan, P.L.; Tapsell, L.C.; Buttemer, W.A. Effects of diets high in whey, soy, red meat and milk protein on body weight maintenance in diet-induced obesity in mice. Nutr. Diet. 2008, 65, S53-S59. [CrossRef]
    • (2008) Nutr. Diet , vol.65 , pp. S53-S59
    • Huang, X.F.1    Liu, H.2    Rahardjo, G.L.3    McLennan, P.L.4    Tapsell, L.C.5    Buttemer, W.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.