Effect of whole soy and purified daidzein on ambulatory blood pressure and endothelial function-a 6-month double-blind, randomized controlled trial among Chinese postmenopausal women with prehypertension

European Journal of Clinical Nutrition

Volumn 69, Issue 10, 2015, Pages 1161-1168

  Liu, Z M ^a   Ho, S C ^a   Chen, Y M ^b   Tomlinson, B ^a   To, K ^a   Woo, J ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DAIDZEIN; EQUOL; ISOFLAVONE; ISOFLAVONE DERIVATIVE; PHYTOESTROGEN; PLANT EXTRACT;

ADULT; AGED; ARTERY DILATATION; ARTICLE; BEVERAGE; BLOOD PRESSURE MONITORING; BLOOD VESSEL FUNCTION; BRACHIAL ARTERY; CHINESE; CLINICAL PROTOCOL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ENDOTHELIUM; FEMALE; HUMAN; HYPERTENSION; INTENTION TO TREAT ANALYSIS; MAJOR CLINICAL STUDY; MILK; OUTCOME ASSESSMENT; PARALLEL DESIGN; POSTMENOPAUSE; PREHYPERTENSION; PROTOCOL COMPLIANCE; RANDOMIZED CONTROLLED TRIAL; SOYBEAN MEAL; URINE LEVEL; BLOOD PRESSURE; CHEMISTRY; CHINA; DRUG EFFECTS; METABOLISM; MIDDLE AGED; PLANT SEED; SOY FOOD; SOYBEAN; VASCULAR ENDOTHELIUM; VASODILATATION;

BLOOD PRESSURE; BLOOD PRESSURE MONITORING, AMBULATORY; CHINA; DOUBLE-BLIND METHOD; ENDOTHELIUM, VASCULAR; EQUOL; FEMALE; HUMANS; HYPERTENSION; ISOFLAVONES; MIDDLE AGED; PHYTOESTROGENS; PLANT EXTRACTS; POSTMENOPAUSE; PREHYPERTENSION; SEEDS; SOY FOODS; SOYBEANS; VASODILATION;

EID: 84943666303     PISSN: 09543007     EISSN: 14765640     Source Type: Journal    
DOI: 10.1038/ejcn.2015.24     Document Type: Article

References (43)

1. Chobanian A, Bakris G, Black H, Cushman W, Green L, Izzo J et al. The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA 2003; 289: 2560-2572.
2. Mosca L, Appel LJ, Benjamin EJ, Berra K, Chandra-Strobos N, Fabunmi RP et al. Evidence-based guidelines for cardiovascular disease prevention in women. Circulation 2004; 109: 672-693.
3. He J, Klag M, Wu Z, Whelton P. Stroke in the People's Republic of China. II. Meta-analysis of hypertension and risk of stroke. Stroke 1995; 26: 2228-2232.
4. August P. Initial treatment of hypertension. N Engl J Med 2003; 348: 610-617.
5. Yang G, Shu XO, Jin F, Zhang X, Li HL, Li Q et al. Longitudinal study of soy food intake and blood pressure among middle-aged and elderly Chinese women. Am J Clin Nutr 2005; 81: 1012-1017.
6. Kokubo Y, Iso H, Ishihara J, Okada K, Inoue M, Tsugane S. Association of dietary intake of soy, beans, and isoflavones with risk of cerebral and myocardial infarctions in Japanese populations: the Japan Public Health Center-based (JPHC) study cohort I. Circulation 2007; 116: 2553-2562.
7. Sharma S, Singh M, Sharma P. Ameliorative effect of daidzein: a caveolin-1 inhibitor in vascular endothelium dysfunction induced by ovariectomy. Indian J Exp Biol 2012; 50: 28-34.
8. Nevala R, Vaskonen T, Vehniainen J, Korpela R, Vapaatalo H. Soy based diet attenuates the development of hypertension when compared to casein based diet in spontaneously hypertensive rat. Life Sci 2000; 66: 115-124.
9. Anderson TJ, Uehata A, Gerhard MD, Meredith IT, Knab S, Delagrange D et al. Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol 1995; 26: 1235-1241.
10. Sacks FM, Lichtenstein A, Van Horn L, Harris W, Kris-Etherton P, Winston M et al. Soy protein, isoflavones, and cardiovascular health. Circulation 2006; 113: 1034-1044.
11. Beavers D, Beavers K, Miller M, Stamey J, Messina M. Exposure to isoflavonecontaining soy products and endothelial function: a Bayesian meta-analysis of randomized controlled trials. Nutr Metab Cardiovasc Dis 2012; 22: 182-191.
12. Roghani M, Vaez Mahdavi MR, Jalali-Nadoushan MR, Baluchnejadmojarad T, Naderi G, Roghani-Dehkordi F et al. Chronic administration of daidzein, a soybean isoflavone, improves endothelial dysfunction and attenuates oxidative stress in streptozotocin-induced diabetic rats. Phytother Res 2012; 27: 112-117.
13. Setchell KD, Brown NM, Lydeking-Olsen E. The clinical importance of the metabolite equol-a clue to the effectiveness of soy and its isoflavones. J Nutr 2002; 132: 3577-3584.
14. Reinwald S, Akabas SR, Weaver CM. Whole versus the piecemeal approach to evaluating soy. J Nutr 2010; 140: 2335S-2343SS.
15. Weaver C, Cheong J. Soy isoflavones and bone health: the relationship is still unclear. J Nutr 2005; 135: 1243-1247.
16. Setchell K, Cole SJ. Method of defining equol-producer status and its frequency among vegetarians. J Nutr 2006; 136: 2188-2193.
17. Liu Z, Ho S, Chen Y, Woo J. Effect of soy protein and isoflavones on blood pressure and endothelial cytokines: a 6-month randomized controlled trial among postmenopausal women. J Hypertens 2012; 29: 29.
18. Song T, Barua K, Buseman G, Murphy P. Soy isoflavone analysis: quality control and a new internal standard. Am J Clin Nutr 1998; 68: 1474S-1479SS.
19. Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves J, Hill MN et al. Recommendations for blood pressure measurement in humans and experimental animals: part 1: blood pressure measurement in humans: a statement for professionals from the subcommittee of professional and public education of the american heart association council on high blood pressure research. Hypertension 2005 p 697-716.
20. Kuvin JT, Patel AR, Sliney KA, Pandian NG, Rand WM, Udelson JE et al. Peripheral vascular endothelial function testing as a noninvasive indicator of coronary artery disease. J Am Coll Cardiol 2001; 38: 1843-1849.
21. Duncan AM, Merz-Demlow BE, Xu X, Phipps WR, Kurzer MS. Premenopausal equol excretors show plasma hormone profiles associated with lowered risk of breast cancer. Cancer Epidemiol Biomarkers Prev 2000; 9: 581-586.
22. Wu J, Oka J, Ezaki J, Ohtomo T, Ueno T, Uchiyama S et al. Possible role of equol status in the effects of isoflavone on bone and fat mass in postmenopausal Japanese women: a double-blind, randomized, controlled trial. Menopause 2007; 14: 866-874.
23. Liu XX, Li SH, Chen JZ, Sun K, Wang XJ, Wang XG et al. Effect of soy isoflavones on blood pressure: a meta-analysis of randomized controlled trials. Nutr Metab Cardiovasc Dis 2012; 22: 463-470.
24. Meyer BJ, Larkin TA, Owen AJ, Astheimer LB, Tapsell LC, Howe PR. Limited lipid-lowering effects of regular consumption of whole soybean foods. Ann Nutr Metab 2004; 48: 67-78.
25. Kurowska EM, Jordan J, Spence JD, Wetmore S, Piche LA, Radzikowski M et al. Effects of substituting dietary soybean protein and oil for milk protein and fat in subjects with hypercholesterolemia. Clin Invest Med 1997; 20: 162-170.
26. Azadbakht L, Nurbakhsh S. Effect of soy drink replacement in a weight reducing diet on anthropometric values and blood pressure among overweight and obese female youths. Asia Pac J Clin Nutr 2011; 20: 383-389.
27. Rivas M, Garay RP, Escanero JF, Cia P Jr, Cia P, Alda JO. Soy milk lowers blood pressure in men and women with mild to moderate essential hypertension. J Nutr 2002; 132: 1900-1902.
28. Li Y, Wang J, Gao P, Guo H, Nawrot T, Wang G et al. Are published characteristics of the ambulatory blood pressure generalizable to rural Chinese? The JingNing population study. Blood Press Monit 2005; 10: 125-134.
29. Zhao ZY, Wang YQ, Yan ZH, Cui J, Li YY. Quantitative study of circadian variations of ambulatory blood pressure in Chinese healthy, hypertensive, and diabetes subjects. Clin Exp Hypertens 2005; 27: 187-194.
30. He J, Wofford MR, Reynolds K, Chen J, Chen CS, Myers L et al. Effect of dietary protein supplementation on blood pressure: a randomized, controlled trial. Circulation 2011; 124: 589-595.
31. Sathyapalan T, Manuchehri AM, Thatcher NJ, Rigby AS, Chapman T, Kilpatrick ES et al. The effect of soy phytoestrogen supplementation on thyroid status and cardiovascular risk markers in patients with subclinical hypothyroidism: a randomized, double-blind, crossover study. J Clin Endocrinol Metab 2011; 96: 1442-1449.
32. Welty FK, Lee KS, Lew NS, Zhou JR. Effect of soy nuts on blood pressure and lipid levels in hypertensive, prehypertensive, and normotensive postmenopausal women. Arc Intern Med 2007; 167: 1060-1067.
33. Nestel P, Fujii A, Zhang L. An isoflavone metabolite reduces arterial stiffness and blood pressure in overweight men and postmenopausal women. Atherosclerosis 2007; 192: 184-189.
34. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr. et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 2003; 42: 1206-1252.
35. Stamler J, Stamler R, Neaton J. Blood pressure, systolic and diastolic, and cardiovascular risks. US population data. Arch Intern Med 1993; 153: 598-615.
36. Li S, Liu X, Bai Y, Wang X, Sun K, Chen J et al. Effect of oral isoflavone supplementation on vascular endothelial function in postmenopausal women: a metaanalysis of randomized placebo-controlled trials. Am J Clin Nutr 2010; 91: 480-486.
37. Rivas M, Garay RP, Escanero JF, Cia P Jr, Cia P, Alda JO. Soy milk lowers blood pressure in men and women with mild to moderate essential hypertension. J Nutr 2002; 132: 1900-1902.
38. Teede HJ, Dalais FS, Kotsopoulos D, Liang Y-L, Davis S, McGrath BP. Dietary soy has both beneficial and potentially adverse cardiovascular effects: a placebo-controlled study in men and postmenopausal w omen. J Clin Endocrinol Metab 2001; 86: 3053-3060.
39. Society CN Dietary Guidelines For Chinese Residents 2007. Available from: http://www.cnsoc.org/.
40. 2007; Available from: http://www.cnsoc.org/. 40 Zhang X, Shu XO, Gao YT, Yang G, Li Q, Li H et al. Soy food consumption is associated with lower risk of coronary heart disease in Chinese women. J Nutr 2003; 133: 2874-2878.
41. Villegas R, Gao YT, Yang G, Li HL, Elasy TA, Zheng W et al. Legume and soy food intake and the incidence of type 2 diabetes in the Shanghai Women's Health Study. Am J Clin Nutr 2008; 87: 162-167.
42. Kris-Etherton P, Grieger J, Hilpert K, West S. Milk products, dietary patterns and blood pressure management. J Am Coll Nutr 2009; 28: 103S-119SS.
43. Weiss G, Skurnick J, Goldsmith L, Santoro N, Park S. Menopause and hypothalamic-pituitary sensitivity to estrogen. JAMA 2004; 292: 2991-2996.