Genistein reduces hyperglycemia and islet cell loss in a high-dosage manner in rats with alloxan-induced pancreatic damage

Pancreas

Volumn 40, Issue 3, 2011, Pages 396-402

  Yang, Weixia ^a   Wang, Siwang ^b   Li, Li ^c   Liang, Zongsuo ^a   Wang, Lisheng ^c  

^a NORTHWEST A F UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF OTTAWA   (Canada)

Author keywords

alloxan induced pancreatic damage; diabetes; dosage dependent; genistein; islet cells; SD rats

Indexed keywords

ALLOXAN; GENISTEIN; GLUCOSE; INSULIN;

ALLOXAN DIABETES MELLITUS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CELL CULTURE; CELL ISOLATION; CELL LOSS; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG MEGADOSE; FEEDING; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; HYPERGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN SYNTHESIS; LOW DRUG DOSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PANCREAS INJURY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; SUPERNATANT; WEIGHT REDUCTION;

ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GENISTEIN; GLUCOSE TOLERANCE TEST; HYPERGLYCEMIA; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MALE; RATS; RATS, SPRAGUE-DAWLEY; WEIGHT LOSS;

EID: 79954426590     PISSN: 08853177     EISSN: 15364828     Source Type: Journal    
DOI: 10.1097/MPA.0b013e318204e74d     Document Type: Article

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