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Volumn 132, Issue , 2016, Pages 1-46

Context- and Tissue-Specific Regulation of Immunity and Tolerance by Regulatory T Cells

Author keywords

FOXP3; Regulation; Regulatory T cell; Suppression; Thymus; Tissue

Indexed keywords

CELL MATURATION; CELLULAR DISTRIBUTION; CYTOKINE RELEASE; DENDRITIC CELL; HUMAN; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOLOGICAL TOLERANCE; IMMUNOPATHOLOGY; IMMUNOREGULATION; INTESTINE CELL; INTRAPERITONEAL FAT; LUNG ALVEOLUS CELL; LYMPHOCYTE FUNCTION; LYMPHOID TISSUE; METABOLIC DISORDER; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SKELETAL MUSCLE CELL; SKIN CELL; ANIMAL; ANTIBODY SPECIFICITY; IMMUNITY; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT; METABOLISM; T LYMPHOCYTE SUBPOPULATION;

EID: 84999663732     PISSN: 00652776     EISSN: 15578445     Source Type: Book Series    
DOI: 10.1016/bs.ai.2016.08.002     Document Type: Chapter
Times cited : (11)

References (241)
  • 1
    • 84875427488 scopus 로고    scopus 로고
    • Regulatory T cells: Recommendations to simplify the nomenclature
    • Abbas, A.K., Benoist, C., Bluestone, J.A., Campbell, D.J., Ghosh, S., Hori, S., et al. Regulatory T cells: Recommendations to simplify the nomenclature. Nature Immunology 14:4 (2013), 307–308 http://doi.org/10.1038/ni.2554.
    • (2013) Nature Immunology , vol.14 , Issue.4 , pp. 307-308
    • Abbas, A.K.1    Benoist, C.2    Bluestone, J.A.3    Campbell, D.J.4    Ghosh, S.5    Hori, S.6
  • 2
    • 32244445416 scopus 로고    scopus 로고
    • Natural regulatory T cells control the development of atherosclerosis in mice
    • Ait-Oufella, H., Salomon, B.L., Potteaux, S., Robertson, A.-K.L., Gourdy, P., Zoll, J., et al. Natural regulatory T cells control the development of atherosclerosis in mice. Nature Medicine 12:2 (2006), 178–180 http://doi.org/10.1038/nm1343.
    • (2006) Nature Medicine , vol.12 , Issue.2 , pp. 178-180
    • Ait-Oufella, H.1    Salomon, B.L.2    Potteaux, S.3    Robertson, A.-K.L.4    Gourdy, P.5    Zoll, J.6
  • 3
    • 33847163271 scopus 로고    scopus 로고
    • CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis
    • Anderson, C.F., Oukka, M., Kuchroo, V.J., Sacks, D., CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. Journal of Experimental Medicine 204:2 (2007), 285–297 http://doi.org/10.1084/jem.20061886.
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.2 , pp. 285-297
    • Anderson, C.F.1    Oukka, M.2    Kuchroo, V.J.3    Sacks, D.4
  • 4
    • 0037603323 scopus 로고    scopus 로고
    • Interleukin-10 in the regulation of T cell-induced colitis
    • Annacker, O., Asseman, C., Read, S., Powrie, F., Interleukin-10 in the regulation of T cell-induced colitis. Journal of Autoimmunity 20:4 (2003), 277–279 http://doi.org/10.1016/S0896-8411(03)00045-3.
    • (2003) Journal of Autoimmunity , vol.20 , Issue.4 , pp. 277-279
    • Annacker, O.1    Asseman, C.2    Read, S.3    Powrie, F.4
  • 5
    • 0036345337 scopus 로고    scopus 로고
    • Origin of regulatory T cells with known specificity for antigen
    • Apostolou, I., Sarukhan, A., Klein, L., von Boehmer, H., Origin of regulatory T cells with known specificity for antigen. Nature Immunology 3:8 (2002), 756–763.
    • (2002) Nature Immunology , vol.3 , Issue.8 , pp. 756-763
    • Apostolou, I.1    Sarukhan, A.2    Klein, L.3    von Boehmer, H.4
  • 6
    • 34248997759 scopus 로고    scopus 로고
    • Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis
    • Arnold, L., Henry, A., Poron, F., Baba-Amer, Y., van Rooijen, N., Plonquet, A., et al. Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis. Journal of Experimental Medicine 204:5 (2007), 1057–1069 http://doi.org/10.1084/jem.20070075.
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.5 , pp. 1057-1069
    • Arnold, L.1    Henry, A.2    Poron, F.3    Baba-Amer, Y.4    van Rooijen, N.5    Plonquet, A.6
  • 7
    • 84940380928 scopus 로고    scopus 로고
    • A distinct function of regulatory T cells in tissue protection
    • Arpaia, N., Green, J.A., Moltedo, B., Arvey, A., Hemmers, S., Yuan, S., et al. A distinct function of regulatory T cells in tissue protection. Cell 162:5 (2015), 1078–1089 http://doi.org/10.1016/j.cell.2015.08.021.
    • (2015) Cell , vol.162 , Issue.5 , pp. 1078-1089
    • Arpaia, N.1    Green, J.A.2    Moltedo, B.3    Arvey, A.4    Hemmers, S.5    Yuan, S.6
  • 8
    • 0029788211 scopus 로고    scopus 로고
    • Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
    • Asano, M., Toda, M., Sakaguchi, N., Sakaguchi, S., Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. Journal of Experimental Medicine 184:2 (1996), 387–396.
    • (1996) Journal of Experimental Medicine , vol.184 , Issue.2 , pp. 387-396
    • Asano, M.1    Toda, M.2    Sakaguchi, N.3    Sakaguchi, S.4
  • 9
    • 34248598295 scopus 로고    scopus 로고
    • Selection of Foxp3 + regulatory T cells specific for self antigen expressed and presented by Aire + medullary thymic epithelial cells
    • Aschenbrenner, K., D'Cruz, L.M., Vollmann, E.H., Hinterberger, M., Emmerich, J., Swee, L.K., et al. Selection of Foxp3 + regulatory T cells specific for self antigen expressed and presented by Aire + medullary thymic epithelial cells. Nature Immunology 8:4 (2007), 351–358 http://doi.org/10.1038/ni1444.
    • (2007) Nature Immunology , vol.8 , Issue.4 , pp. 351-358
    • Aschenbrenner, K.1    D'Cruz, L.M.2    Vollmann, E.H.3    Hinterberger, M.4    Emmerich, J.5    Swee, L.K.6
  • 10
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
    • Asseman, C., Mauze, S., Leach, M.W., Coffman, R.L., Powrie, F., An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. Journal of Experimental Medicine 190:7 (1999), 995–1004 http://doi.org/10.1084/jem.190.7.995.
    • (1999) Journal of Experimental Medicine , vol.190 , Issue.7 , pp. 995-1004
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffman, R.L.4    Powrie, F.5
  • 11
    • 85027947787 scopus 로고    scopus 로고
    • Induction of colonic regulatory T cells by indigenous clostridium species
    • Atarashi, K., Tanoue, T., Shima, T., Imaoka, A., Kuwahara, T., Momose, Y., et al. Induction of colonic regulatory T cells by indigenous clostridium species. Science 331:6015 (2011), 337–341 http://doi.org/10.1126/science.1198469.
    • (2011) Science , vol.331 , Issue.6015 , pp. 337-341
    • Atarashi, K.1    Tanoue, T.2    Shima, T.3    Imaoka, A.4    Kuwahara, T.5    Momose, Y.6
  • 12
    • 79955158500 scopus 로고    scopus 로고
    • Steady state migratory RelB + langerin + dermal dendritic cells mediate peripheral induction of antigen-specific CD4+CD25+Foxp3 + regulatory T cells
    • Azukizawa, H., Döhler, A., Kanazawa, N., Nayak, A., Lipp, M., Malissen, B., et al. Steady state migratory RelB + langerin + dermal dendritic cells mediate peripheral induction of antigen-specific CD4+CD25+Foxp3 + regulatory T cells. European Journal of Immunology 41:5 (2011), 1420–1434 http://doi.org/10.1002/eji.201040930.
    • (2011) European Journal of Immunology , vol.41 , Issue.5 , pp. 1420-1434
    • Azukizawa, H.1    Döhler, A.2    Kanazawa, N.3    Nayak, A.4    Lipp, M.5    Malissen, B.6
  • 13
    • 33645778289 scopus 로고    scopus 로고
    • MHC class II expression identifies functionally distinct human regulatory T cells
    • Baecher-Allan, C., Wolf, E., Hafler, D.A., MHC class II expression identifies functionally distinct human regulatory T cells. Journal of Immunology 176:8 (2006), 4622–4631 http://doi.org/10.4049/jimmunol.176.8.4622.
    • (2006) Journal of Immunology , vol.176 , Issue.8 , pp. 4622-4631
    • Baecher-Allan, C.1    Wolf, E.2    Hafler, D.A.3
  • 14
    • 34250189127 scopus 로고    scopus 로고
    • Kruppel-like factor 2 controls T cell trafficking by activating L-selectin (CD62L) and sphingosine-1-phosphate receptor 1 transcription
    • Bai, A., Hu, H., Yeung, M., Chen, J., Kruppel-like factor 2 controls T cell trafficking by activating L-selectin (CD62L) and sphingosine-1-phosphate receptor 1 transcription. Journal of Immunology 178:12 (2007), 7632–7639 http://doi.org/10.4049/jimmunol.178.12.7632.
    • (2007) Journal of Immunology , vol.178 , Issue.12 , pp. 7632-7639
    • Bai, A.1    Hu, H.2    Yeung, M.3    Chen, J.4
  • 15
    • 33751231701 scopus 로고    scopus 로고
    • FOXP3 + regulatory T cells: Current controversies and future perspectives
    • Banham, A.H., Powrie, F.M., Suri-Payer, E., FOXP3 + regulatory T cells: Current controversies and future perspectives. European Journal of Immunology 36:11 (2006), 2832–2836 http://doi.org/10.1002/eji.200636459.
    • (2006) European Journal of Immunology , vol.36 , Issue.11 , pp. 2832-2836
    • Banham, A.H.1    Powrie, F.M.2    Suri-Payer, E.3
  • 16
    • 77954591796 scopus 로고    scopus 로고
    • CD69 suppresses sphingosine 1-phosophate receptor-1 (S1P1) function through interaction with membrane helix 4
    • Bankovich, A.J., Shiow, L.R., Cyster, J.G., CD69 suppresses sphingosine 1-phosophate receptor-1 (S1P1) function through interaction with membrane helix 4. The Journal of Biological Chemistry 285:29 (2010), 22328–22337 http://doi.org/10.1074/jbc.M110.123299.
    • (2010) The Journal of Biological Chemistry , vol.285 , Issue.29 , pp. 22328-22337
    • Bankovich, A.J.1    Shiow, L.R.2    Cyster, J.G.3
  • 17
    • 34548755672 scopus 로고    scopus 로고
    • DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3 + conventional T cells
    • Baron, U., Floess, S., Wieczorek, G., Baumann, K., Grützkau, A., Dong, J., et al. DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3 + conventional T cells. European Journal of Immunology 37:9 (2007), 2378–2389 http://doi.org/10.1002/eji.200737594.
    • (2007) European Journal of Immunology , vol.37 , Issue.9 , pp. 2378-2389
    • Baron, U.1    Floess, S.2    Wieczorek, G.3    Baumann, K.4    Grützkau, A.5    Dong, J.6
  • 18
    • 73249141893 scopus 로고    scopus 로고
    • The Tregs’ world according to GARP
    • Battaglia, M., Roncarolo, M.G., The Tregs’ world according to GARP. European Journal of Immunology 39:12 (2009), 3296–3300 http://doi.org/10.1002/eji.200940117.
    • (2009) European Journal of Immunology , vol.39 , Issue.12 , pp. 3296-3300
    • Battaglia, M.1    Roncarolo, M.G.2
  • 19
    • 33846260244 scopus 로고    scopus 로고
    • Coordinated control of immunity to muscle stage Trichinella spiralis by IL-10, regulatory T cells, and TGF-beta
    • Beiting, D.P., Gagliardo, L.F., Hesse, M., Bliss, S.K., Meskill, D., Appleton, J.A., Coordinated control of immunity to muscle stage Trichinella spiralis by IL-10, regulatory T cells, and TGF-beta. Journal of Immunology 178:2 (2007), 1039–1047 http://doi.org/10.4049/jimmunol.178.2.1039.
    • (2007) Journal of Immunology , vol.178 , Issue.2 , pp. 1039-1047
    • Beiting, D.P.1    Gagliardo, L.F.2    Hesse, M.3    Bliss, S.K.4    Meskill, D.5    Appleton, J.A.6
  • 20
    • 2242423605 scopus 로고    scopus 로고
    • CD4+CD25 + regulatory T cells control Leishmania major persistence and immunity
    • Belkaid, Y., Piccirillo, C.A., Mendez, S., Shevach, E.M., Sacks, D.L., CD4+CD25 + regulatory T cells control Leishmania major persistence and immunity. Nature 420:6915 (2002), 502–507.
    • (2002) Nature , vol.420 , Issue.6915 , pp. 502-507
    • Belkaid, Y.1    Piccirillo, C.A.2    Mendez, S.3    Shevach, E.M.4    Sacks, D.L.5
  • 21
    • 84971247648 scopus 로고    scopus 로고
    • The influence of skin microorganisms on cutaneous immunity
    • Belkaid, Y., Tamoutounour, S., The influence of skin microorganisms on cutaneous immunity. Nature Reviews. Immunology 16:6 (2016), 353–366 http://doi.org/10.1038/nri.2016.48.
    • (2016) Nature Reviews. Immunology , vol.16 , Issue.6 , pp. 353-366
    • Belkaid, Y.1    Tamoutounour, S.2
  • 22
    • 77953721901 scopus 로고    scopus 로고
    • Characterization of the novel ST2/IL-33 system in patients with inflammatory bowel disease
    • Beltrán, C.J., Núñez, L.E., Díaz-Jiménez, D., Farfan, N., Candia, E., Heine, C., et al. Characterization of the novel ST2/IL-33 system in patients with inflammatory bowel disease. Inflammatory Bowel Diseases 16:7 (2010), 1097–1107 http://doi.org/10.1002/ibd.21175.
    • (2010) Inflammatory Bowel Diseases , vol.16 , Issue.7 , pp. 1097-1107
    • Beltrán, C.J.1    Núñez, L.E.2    Díaz-Jiménez, D.3    Farfan, N.4    Candia, E.5    Heine, C.6
  • 23
    • 34347375745 scopus 로고    scopus 로고
    • Expansion and characteristics of human T regulatory type 1 cells in co-cultures simulating tumor microenvironment
    • Bergmann, C., Strauss, L., Zeidler, R., Lang, S., Whiteside, T.L., Expansion and characteristics of human T regulatory type 1 cells in co-cultures simulating tumor microenvironment. Cancer Immunology, Immunotherapy 56:9 (2007), 1429–1442 http://doi.org/10.1007/s00262-007-0280-9.
    • (2007) Cancer Immunology, Immunotherapy , vol.56 , Issue.9 , pp. 1429-1442
    • Bergmann, C.1    Strauss, L.2    Zeidler, R.3    Lang, S.4    Whiteside, T.L.5
  • 24
    • 33846508133 scopus 로고    scopus 로고
    • The evolutionary history of lymphoid organs
    • Boehm, T., Bleul, C.C., The evolutionary history of lymphoid organs. Nature Immunology 8:2 (2007), 131–135 http://doi.org/10.1038/ni1435.
    • (2007) Nature Immunology , vol.8 , Issue.2 , pp. 131-135
    • Boehm, T.1    Bleul, C.C.2
  • 25
    • 34250376423 scopus 로고    scopus 로고
    • Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression
    • Bopp, T., Becker, C., Klein, M., Klein-Hessling, S., Palmetshofer, A., Serfling, E., et al. Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression. The Journal of Experimental Medicine 204:6 (2007), 1303–1310 http://doi.org/10.1084/jem.20062129.
    • (2007) The Journal of Experimental Medicine , vol.204 , Issue.6 , pp. 1303-1310
    • Bopp, T.1    Becker, C.2    Klein, M.3    Klein-Hessling, S.4    Palmetshofer, A.5    Serfling, E.6
  • 26
    • 34547098277 scopus 로고    scopus 로고
    • Expression of ectonucleotidase CD39 by Foxp3 + Treg cells: Hydrolysis of extracellular ATP and immune suppression
    • Borsellino, G., Kleinewietfeld, M., Di Mitri, D., Sternjak, A., Diamantini, A., Giometto, R., et al. Expression of ectonucleotidase CD39 by Foxp3 + Treg cells: Hydrolysis of extracellular ATP and immune suppression. Blood 110:4 (2007), 1225–1232 http://doi.org/10.1182/blood-2006-12-064527.
    • (2007) Blood , vol.110 , Issue.4 , pp. 1225-1232
    • Borsellino, G.1    Kleinewietfeld, M.2    Di Mitri, D.3    Sternjak, A.4    Diamantini, A.5    Giometto, R.6
  • 27
    • 0034179765 scopus 로고    scopus 로고
    • Visceral obesity and metabolic syndrome
    • Bosello, O., Zamboni, M., Visceral obesity and metabolic syndrome. Obesity Reviews 1:1 (2000), 47–56 http://doi.org/10.1046/j.1467-789x.2000.00008.x.
    • (2000) Obesity Reviews , vol.1 , Issue.1 , pp. 47-56
    • Bosello, O.1    Zamboni, M.2
  • 28
    • 84944754761 scopus 로고    scopus 로고
    • + Treg compared to Foxp3—Conventional T cells to TCR-independent signals for CD69 induction
    • + Treg compared to Foxp3—Conventional T cells to TCR-independent signals for CD69 induction. PLoS One, 10(9), 2015, e0137393 http://doi.org/10.1371/journal.pone.0137393.
    • (2015) PLoS One , vol.10 , Issue.9 , pp. e0137393
    • Bremser, A.1    Brack, M.2    Izcue, A.3
  • 29
    • 84883830476 scopus 로고    scopus 로고
    • Convergences and divergences of thymus- and peripherally derived regulatory T cells in cancer
    • Burocchi, A., Colombo, M.P., Piconese, S., Convergences and divergences of thymus- and peripherally derived regulatory T cells in cancer. Frontiers in Immunology, 4, 2013, 247 http://doi.org/10.3389/fimmu.2013.00247.
    • (2013) Frontiers in Immunology , vol.4 , pp. 247
    • Burocchi, A.1    Colombo, M.P.2    Piconese, S.3
  • 30
    • 84890050252 scopus 로고    scopus 로고
    • A special populationof regulatory T cells potentiates muscle repair
    • Burzyn, D., Kuswanto, W., Kolodin, D., Shadrach, J.L., Cerletti, M., Jang, Y., et al. A special populationof regulatory T cells potentiates muscle repair. Cell 155:6 (2013), 1282–1295 http://doi.org/10.1016/j.cell.2013.10.054.
    • (2013) Cell , vol.155 , Issue.6 , pp. 1282-1295
    • Burzyn, D.1    Kuswanto, W.2    Kolodin, D.3    Shadrach, J.L.4    Cerletti, M.5    Jang, Y.6
  • 32
    • 35449006679 scopus 로고    scopus 로고
    • Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance
    • Cao, X., Cai, S.F., Fehniger, T.A., Song, J., Collins, L.I., Piwnica-Worms, D.R., et al. Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance. Immunity 27:4 (2007), 635–646 http://doi.org/10.1016/j.immuni.2007.08.014.
    • (2007) Immunity , vol.27 , Issue.4 , pp. 635-646
    • Cao, X.1    Cai, S.F.2    Fehniger, T.A.3    Song, J.4    Collins, L.I.5    Piwnica-Worms, D.R.6
  • 33
    • 33746334804 scopus 로고    scopus 로고
    • Kruppel-like factor 2 regulates thymocyte and T-cell migration
    • Carlson, C.M., Endrizzi, B.T., Wu, J., Ding, X., Weinreich, M.A., Walsh, E.R., et al. Kruppel-like factor 2 regulates thymocyte and T-cell migration. Nature 442:7100 (2006), 299–302 http://doi.org/10.1038/nature04882.
    • (2006) Nature , vol.442 , Issue.7100 , pp. 299-302
    • Carlson, C.M.1    Endrizzi, B.T.2    Wu, J.3    Ding, X.4    Weinreich, M.A.5    Walsh, E.R.6
  • 34
    • 84929965822 scopus 로고    scopus 로고
    • Eosinophils orchestrate cancer rejection by normalizing tumor vessels and enhancing infiltration of CD8 + T cells
    • Carretero, R., Sektioglu, I.M., Garbi, N., Salgado, O.C., Beckhove, P., Hämmerling, G.J., Eosinophils orchestrate cancer rejection by normalizing tumor vessels and enhancing infiltration of CD8 + T cells. Nature Immunology 16:6 (2015), 609–617 http://doi.org/10.1038/ni.3159.
    • (2015) Nature Immunology , vol.16 , Issue.6 , pp. 609-617
    • Carretero, R.1    Sektioglu, I.M.2    Garbi, N.3    Salgado, O.C.4    Beckhove, P.5    Hämmerling, G.J.6
  • 35
    • 37849009964 scopus 로고    scopus 로고
    • A two-step process for thymic regulatory T cell development
    • Chan-Wang Joaquim Lio, C.-S.H., A two-step process for thymic regulatory T cell development. Immunity 28:1 (2008), 100–111 http://doi.org/10.1016/j.immuni.2007.11.021.
    • (2008) Immunity , vol.28 , Issue.1 , pp. 100-111
    • Chan-Wang Joaquim Lio, C.-S.H.1
  • 36
    • 70049113279 scopus 로고    scopus 로고
    • CD4 + regulatory T cells control TH17 responses in a Stat3-dependent manner
    • Chaudhry, A., Rudra, D., Treuting, P., Samstein, R.M., Liang, Y., Kas, A., et al. CD4 + regulatory T cells control TH17 responses in a Stat3-dependent manner. Science 326:5955 (2009), 986–991 http://doi.org/10.1126/science.1172702.
    • (2009) Science , vol.326 , Issue.5955 , pp. 986-991
    • Chaudhry, A.1    Rudra, D.2    Treuting, P.3    Samstein, R.M.4    Liang, Y.5    Kas, A.6
  • 37
    • 79954608612 scopus 로고    scopus 로고
    • Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation
    • Chaudhry, A., Samstein, R.M., Treuting, P., Liang, Y., Pils, M.C., Heinrich, J.-M., et al. Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation. Immunity 34:4 (2011), 566–578 http://doi.org/10.1016/j.immuni.2011.03.018.
    • (2011) Immunity , vol.34 , Issue.4 , pp. 566-578
    • Chaudhry, A.1    Samstein, R.M.2    Treuting, P.3    Liang, Y.4    Pils, M.C.5    Heinrich, J.-M.6
  • 38
    • 84862986986 scopus 로고    scopus 로고
    • PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells
    • Cipolletta, D., Feuerer, M., Li, A., Kamei, N., Lee, J., Shoelson, S.E., et al. PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells. Nature 486:7404 (2012), 549–553 http://doi.org/10.1038/nature11132.
    • (2012) Nature , vol.486 , Issue.7404 , pp. 549-553
    • Cipolletta, D.1    Feuerer, M.2    Li, A.3    Kamei, N.4    Lee, J.5    Shoelson, S.E.6
  • 39
    • 33846005781 scopus 로고    scopus 로고
    • IL-15 and dermal fibroblasts induce proliferation of natural regulatory T cells isolated from human skin
    • Clark, R.A., Kupper, T.S., IL-15 and dermal fibroblasts induce proliferation of natural regulatory T cells isolated from human skin. Blood 109:1 (2007), 194–202 http://doi.org/10.1182/blood-2006-02-002873.
    • (2007) Blood , vol.109 , Issue.1 , pp. 194-202
    • Clark, R.A.1    Kupper, T.S.2
  • 41
    • 36549030784 scopus 로고    scopus 로고
    • The inhibitory cytokine IL-35 contributes to regulatory T-cell function
    • Collison, L.W., Workman, C.J., Kuo, T.T., Boyd, K., Wang, Y., Vignali, K.M., et al. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 450:7169 (2007), 566–569 http://doi.org/10.1038/nature06306.
    • (2007) Nature , vol.450 , Issue.7169 , pp. 566-569
    • Collison, L.W.1    Workman, C.J.2    Kuo, T.T.3    Boyd, K.4    Wang, Y.5    Vignali, K.M.6
  • 42
    • 84919795588 scopus 로고    scopus 로고
    • The impact of diet and lifestyle on gut microbiota and human health
    • Conlon, M., Bird, A., The impact of diet and lifestyle on gut microbiota and human health. Nutrients 7:1 (2015), 17–44 http://doi.org/10.3390/nu7010017.
    • (2015) Nutrients , vol.7 , Issue.1 , pp. 17-44
    • Conlon, M.1    Bird, A.2
  • 43
    • 84958012871 scopus 로고    scopus 로고
    • CCR7 controls thymus recirculation, but not production and emigration, of Foxp3 + T cells
    • Cowan, J.E., McCarthy, N.I., Anderson, G., CCR7 controls thymus recirculation, but not production and emigration, of Foxp3 + T cells. Cell Reports 14:5 (2016), 1041–1048 http://doi.org/10.1016/j.celrep.2016.01.003.
    • (2016) Cell Reports , vol.14 , Issue.5 , pp. 1041-1048
    • Cowan, J.E.1    McCarthy, N.I.2    Anderson, G.3
  • 45
    • 4644369302 scopus 로고    scopus 로고
    • Interleukin-2 is essential for CD4+CD25 + regulatory T cell function
    • de la Rosa, M., Rutz, S., Dorninger, H., Scheffold, A., Interleukin-2 is essential for CD4+CD25 + regulatory T cell function. European Journal of Immunology 34:9 (2004), 2480–2488 http://doi.org/10.1002/eji.200425274.
    • (2004) European Journal of Immunology , vol.34 , Issue.9 , pp. 2480-2488
    • de la Rosa, M.1    Rutz, S.2    Dorninger, H.3    Scheffold, A.4
  • 46
    • 34250351459 scopus 로고    scopus 로고
    • Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
    • Deaglio, S., Dwyer, K.M., Gao, W., Friedman, D., Usheva, A., Erat, A., et al. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. The Journal of Experimental Medicine 204:6 (2007), 1257–1265.
    • (2007) The Journal of Experimental Medicine , vol.204 , Issue.6 , pp. 1257-1265
    • Deaglio, S.1    Dwyer, K.M.2    Gao, W.3    Friedman, D.4    Usheva, A.5    Erat, A.6
  • 47
    • 79551529432 scopus 로고    scopus 로고
    • Visceral adipose inflammation in obesity is associated with critical alterations in tregulatory cell numbers
    • Deiuliis, J., Shah, Z., Shah, N., Needleman, B., Mikami, D., Narula, V., et al. Visceral adipose inflammation in obesity is associated with critical alterations in tregulatory cell numbers. PLoS One, 6(1), 2011, e16376 http://doi.org/10.1371/journal.pone.0016376.
    • (2011) PLoS One , vol.6 , Issue.1 , pp. e16376
    • Deiuliis, J.1    Shah, Z.2    Shah, N.3    Needleman, B.4    Mikami, D.5    Narula, V.6
  • 48
  • 49
    • 0035806244 scopus 로고    scopus 로고
    • Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood
    • Dieckmann, D., Plottner, H., Berchtold, S., Berger, T., Schuler, G., Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. Journal of Experimental Medicine 193:11 (2001), 1303–1310.
    • (2001) Journal of Experimental Medicine , vol.193 , Issue.11 , pp. 1303-1310
    • Dieckmann, D.1    Plottner, H.2    Berchtold, S.3    Berger, T.4    Schuler, G.5
  • 50
    • 84859193457 scopus 로고    scopus 로고
    • Differential pattern and prognostic significance of CD4 +, FOXP3 + and IL-17 + tumor infiltrating lymphocytes in ductal and lobular breast cancers
    • Droeser, R., Zlobec, I., Kilic, E., Güth, U., Heberer, M., Spagnoli, G., et al. Differential pattern and prognostic significance of CD4 +, FOXP3 + and IL-17 + tumor infiltrating lymphocytes in ductal and lobular breast cancers. BMC Cancer, 12(1), 2012, 1 http://doi.org/10.1186/1471-2407-12-134.
    • (2012) BMC Cancer , vol.12 , Issue.1 , pp. 1
    • Droeser, R.1    Zlobec, I.2    Kilic, E.3    Güth, U.4    Heberer, M.5    Spagnoli, G.6
  • 51
    • 84861039642 scopus 로고    scopus 로고
    • Functionally distinct subsets of human FOXP3 + Treg cells that phenotypically mirror effector Th cells
    • Duhen, T., Duhen, R., Lanzavecchia, A., Sallusto, F., Campbell, D.J., Functionally distinct subsets of human FOXP3 + Treg cells that phenotypically mirror effector Th cells. Blood 119:19 (2012), 4430–4440 http://doi.org/10.1182/blood-2011-11-392324.
    • (2012) Blood , vol.119 , Issue.19 , pp. 4430-4440
    • Duhen, T.1    Duhen, R.2    Lanzavecchia, A.3    Sallusto, F.4    Campbell, D.J.5
  • 52
    • 10844288839 scopus 로고    scopus 로고
    • Uncoupling of IL-2 signaling from cell cycle progression in naive CD4 + T cells by regulatory CD4+CD25 + T lymphocytes
    • Duthoit, C.T., Mekala, D.J., Alli, R.S., Geiger, T.L., Uncoupling of IL-2 signaling from cell cycle progression in naive CD4 + T cells by regulatory CD4+CD25 + T lymphocytes. Journal of Immunology 174:1 (2005), 155–163 http://doi.org/10.4049/jimmunol.174.1.155.
    • (2005) Journal of Immunology , vol.174 , Issue.1 , pp. 155-163
    • Duthoit, C.T.1    Mekala, D.J.2    Alli, R.S.3    Geiger, T.L.4
  • 53
    • 33745298438 scopus 로고    scopus 로고
    • Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10
    • Eksteen, B., Miles, A., Curbishley, S.M., Tselepis, C., Grant, A.J., Walker, L.S.K., et al. Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10. Journal of Immunology 177:1 (2006), 593–603 http://doi.org/10.4049/jimmunol.177.1.593.
    • (2006) Journal of Immunology , vol.177 , Issue.1 , pp. 593-603
    • Eksteen, B.1    Miles, A.2    Curbishley, S.M.3    Tselepis, C.4    Grant, A.J.5    Walker, L.S.K.6
  • 54
    • 80755168875 scopus 로고    scopus 로고
    • Potential role of regulatory T cells in reversing obesity-linked insulin resistance and diabetic nephropathy
    • Eller, K., Kirsch, A., Wolf, A.M., Sopper, S., Tagwerker, A., Stanzl, U., et al. Potential role of regulatory T cells in reversing obesity-linked insulin resistance and diabetic nephropathy. Diabetes 60:11 (2011), 2954–2962 http://doi.org/10.2337/db11-0358.
    • (2011) Diabetes , vol.60 , Issue.11 , pp. 2954-2962
    • Eller, K.1    Kirsch, A.2    Wolf, A.M.3    Sopper, S.4    Tagwerker, A.5    Stanzl, U.6
  • 55
    • 77954743969 scopus 로고    scopus 로고
    • Cancer inflammation and regulatory T cells
    • Erdman, S.E., Poutahidis, T., Cancer inflammation and regulatory T cells. International Journal of Cancer 127:4 (2010), 768–779 http://doi.org/10.1002/ijc.25430.
    • (2010) International Journal of Cancer , vol.127 , Issue.4 , pp. 768-779
    • Erdman, S.E.1    Poutahidis, T.2
  • 57
  • 58
    • 77957019251 scopus 로고    scopus 로고
    • Cyclic adenosine monophosphate and IL-10 coordinately contribute to nTreg cell-mediated suppression of dendritic cell activation
    • Fassbender, M., Gerlitzki, B., Ullrich, N., Lupp, C., Klein, M., Radsak, M.P., et al. Cyclic adenosine monophosphate and IL-10 coordinately contribute to nTreg cell-mediated suppression of dendritic cell activation. Cellular Immunology 265:2 (2010), 91–96 http://doi.org/10.1016/j.cellimm.2010.07.007.
    • (2010) Cellular Immunology , vol.265 , Issue.2 , pp. 91-96
    • Fassbender, M.1    Gerlitzki, B.2    Ullrich, N.3    Lupp, C.4    Klein, M.5    Radsak, M.P.6
  • 59
    • 68349148211 scopus 로고    scopus 로고
    • Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
    • Feuerer, M., Herrero, L., Cipolletta, D., Naaz, A., Wong, J., Nayer, A., et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nature Medicine 15 (2009), 930–939 http://doi.org/10.1038/nm.2002.
    • (2009) Nature Medicine , vol.15 , pp. 930-939
    • Feuerer, M.1    Herrero, L.2    Cipolletta, D.3    Naaz, A.4    Wong, J.5    Nayer, A.6
  • 60
    • 72849115174 scopus 로고    scopus 로고
    • Origin and evolution of the adaptive immune system: Genetic events and selective pressures
    • Flajnik, M.F., Kasahara, M., Origin and evolution of the adaptive immune system: Genetic events and selective pressures. Nature Reviews. Genetics 11:1 (2010), 47–59 http://doi.org/10.1038/nrg2703.
    • (2010) Nature Reviews. Genetics , vol.11 , Issue.1 , pp. 47-59
    • Flajnik, M.F.1    Kasahara, M.2
  • 62
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory T cells
    • Fontenot, J.D., Rasmussen, J.P., Gavin, M.A., Rudensky, A.Y., A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nature Immunology 6:11 (2005), 1142–1151.
    • (2005) Nature Immunology , vol.6 , Issue.11 , pp. 1142-1151
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3    Rudensky, A.Y.4
  • 63
    • 77951217044 scopus 로고    scopus 로고
    • High frequency of tumor-infiltrating FOXP3 + regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patients
    • Frey, D.M., Droeser, R.A., Viehl, C.T., Zlobec, I., Lugli, A., Zingg, U., et al. High frequency of tumor-infiltrating FOXP3 + regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patients. International Journal of Cancer 126:11 (2010), 2635–2643 http://doi.org/10.1002/ijc.24989.
    • (2010) International Journal of Cancer , vol.126 , Issue.11 , pp. 2635-2643
    • Frey, D.M.1    Droeser, R.A.2    Viehl, C.T.3    Zlobec, I.4    Lugli, A.5    Zingg, U.6
  • 64
    • 63049090504 scopus 로고    scopus 로고
    • CD4 + regulatory T cells require CTLA-4 for the maintenance of systemic tolerance
    • Friedline, R.H., Brown, D.S., Nguyen, H., Kornfeld, H., Lee, J., Zhang, Y., et al. CD4 + regulatory T cells require CTLA-4 for the maintenance of systemic tolerance. The Journal of Experimental Medicine 206:2 (2009), 421–434 http://doi.org/10.1084/jem.20081811.
    • (2009) The Journal of Experimental Medicine , vol.206 , Issue.2 , pp. 421-434
    • Friedline, R.H.1    Brown, D.S.2    Nguyen, H.3    Kornfeld, H.4    Lee, J.5    Zhang, Y.6
  • 65
    • 84890564250 scopus 로고    scopus 로고
    • Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
    • Furusawa, Y., Obata, Y., Fukuda, S., Endo, T.A., Nakato, G., Takahashi, D., et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells. Nature 504 (2013), 446–450 http://doi.org/10.1038/nature12721.
    • (2013) Nature , vol.504 , pp. 446-450
    • Furusawa, Y.1    Obata, Y.2    Fukuda, S.3    Endo, T.A.4    Nakato, G.5    Takahashi, D.6
  • 66
    • 84885778452 scopus 로고    scopus 로고
    • Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells
    • Gao, Y., Nish, S.A., Jiang, R., Hou, L., Licona Limon, P., Weinstein, J.S., et al. Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells. Immunity 39:4 (2013), 722–732 http://doi.org/10.1016/j.immuni.2013.08.028.
    • (2013) Immunity , vol.39 , Issue.4 , pp. 722-732
    • Gao, Y.1    Nish, S.A.2    Jiang, R.3    Hou, L.4    Licona Limon, P.5    Weinstein, J.S.6
  • 67
    • 79956315886 scopus 로고    scopus 로고
    • Intestinal bacterial colonization induces mutualistic regulatory T cell responses
    • Geuking, M.B., Cahenzli, J., Lawson, M.A.E., Ng, D.C.K., Slack, E., Hapfelmeier, S., et al. Intestinal bacterial colonization induces mutualistic regulatory T cell responses. Immunity 34:5 (2011), 794–806 http://doi.org/10.1016/j.immuni.2011.03.021.
    • (2011) Immunity , vol.34 , Issue.5 , pp. 794-806
    • Geuking, M.B.1    Cahenzli, J.2    Lawson, M.A.E.3    Ng, D.C.K.4    Slack, E.5    Hapfelmeier, S.6
  • 69
    • 84902201196 scopus 로고    scopus 로고
    • Lung microbiota promotes tolerance to allergens in neonates via PD-L1
    • Gollwitzer, E.S., Saglani, S., Trompette, A., Yadava, K., Sherburn, R., McCoy, K.D., et al. Lung microbiota promotes tolerance to allergens in neonates via PD-L1. Nature Medicine 20:6 (2014), 642–647 http://doi.org/10.1038/nm.3568.
    • (2014) Nature Medicine , vol.20 , Issue.6 , pp. 642-647
    • Gollwitzer, E.S.1    Saglani, S.2    Trompette, A.3    Yadava, K.4    Sherburn, R.5    McCoy, K.D.6
  • 70
    • 58149290252 scopus 로고    scopus 로고
    • Transplantation survival is maintained by granzyme B + regulatory cells and adaptive regulatory T cells
    • Gondek, D.C., DeVries, V., Nowak, E.C., Lu, L.-F., Bennett, K.A., Scott, Z.A., et al. Transplantation survival is maintained by granzyme B + regulatory cells and adaptive regulatory T cells. Journal of Immunology (Baltimore, Md.: 1950) 181:7 (2008), 4752–4760 http://doi.org/10.4049/jimmunol.181.7.4752.
    • (2008) Journal of Immunology (Baltimore, Md.: 1950) , vol.181 , Issue.7 , pp. 4752-4760
    • Gondek, D.C.1    DeVries, V.2    Nowak, E.C.3    Lu, L.-F.4    Bennett, K.A.5    Scott, Z.A.6
  • 71
    • 13544271161 scopus 로고    scopus 로고
    • Cutting edge: Contact-mediated suppression by CD4+CD25 + regulatory cells involves a granzyme B-dependent, perforin-independent mechanism
    • Gondek, D.C., Lu, L.F., Quezada, S.A., Sakaguchi, S., Noelle, R.J., Cutting edge: Contact-mediated suppression by CD4+CD25 + regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. Journal of Immunology (Baltimore, Md.: 1950) 174:4 (2005), 1783–1786.
    • (2005) Journal of Immunology (Baltimore, Md.: 1950) , vol.174 , Issue.4 , pp. 1783-1786
    • Gondek, D.C.1    Lu, L.F.2    Quezada, S.A.3    Sakaguchi, S.4    Noelle, R.J.5
  • 72
    • 0037124359 scopus 로고    scopus 로고
    • Identification of regulatory T cells in tolerated allografts
    • Graca, L., Cobbold, S.P., Waldmann, H., Identification of regulatory T cells in tolerated allografts. Journal of Experimental Medicine 195:12 (2002), 1641–1646 http://doi.org/10.1084/jem.20012097.
    • (2002) Journal of Experimental Medicine , vol.195 , Issue.12 , pp. 1641-1646
    • Graca, L.1    Cobbold, S.P.2    Waldmann, H.3
  • 73
    • 84892760241 scopus 로고    scopus 로고
    • Regulatory T cells shape the resident memory T cell response to virus infection in the tissues
    • Graham, J.B., Da Costa, A., Lund, J.M., Regulatory T cells shape the resident memory T cell response to virus infection in the tissues. Journal of Immunology (Baltimore, Md.: 1950) 192:2 (2014), 683–690 http://doi.org/10.4049/jimmunol.1202153.
    • (2014) Journal of Immunology (Baltimore, Md.: 1950) , vol.192 , Issue.2 , pp. 683-690
    • Graham, J.B.1    Da Costa, A.2    Lund, J.M.3
  • 75
    • 79952750288 scopus 로고    scopus 로고
    • The skin microbiome
    • Grice, E.A., Segre, J.A., The skin microbiome. Nature Reviews. Microbiology 9:4 (2011), 244–253 http://doi.org/10.1038/nrmicro2537.
    • (2011) Nature Reviews. Microbiology , vol.9 , Issue.4 , pp. 244-253
    • Grice, E.A.1    Segre, J.A.2
  • 76
    • 77951060733 scopus 로고    scopus 로고
    • OX40 is required for regulatory T cell-mediated control of colitis
    • Griseri, T., Asquith, M., Thompson, C., Powrie, F., OX40 is required for regulatory T cell-mediated control of colitis. The Journal of Experimental Medicine 207:4 (2010), 699–709 http://doi.org/10.1084/jem.20091618.
    • (2010) The Journal of Experimental Medicine , vol.207 , Issue.4 , pp. 699-709
    • Griseri, T.1    Asquith, M.2    Thompson, C.3    Powrie, F.4
  • 77
    • 5644238762 scopus 로고    scopus 로고
    • Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells
    • Grossman, W.J., Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells. Blood 104:9 (2004), 2840–2848 http://doi.org/10.1182/blood-2004-03-0859.
    • (2004) Blood , vol.104 , Issue.9 , pp. 2840-2848
    • Grossman, W.J.1
  • 78
    • 77950408684 scopus 로고    scopus 로고
    • Skin-draining lymph nodes contain dermis-derived CD103 − dendritic cells that constitutively produce retinoic acid and induce Foxp3 + regulatory T cells
    • Guilliams, M., Crozat, K., Henri, S., Tamoutounour, S., Grenot, P., Devilard, E., et al. Skin-draining lymph nodes contain dermis-derived CD103 − dendritic cells that constitutively produce retinoic acid and induce Foxp3 + regulatory T cells. Blood 115:10 (2010), 1958–1968 http://doi.org/10.1182/blood-2009-09-245274.
    • (2010) Blood , vol.115 , Issue.10 , pp. 1958-1968
    • Guilliams, M.1    Crozat, K.2    Henri, S.3    Tamoutounour, S.4    Grenot, P.5    Devilard, E.6
  • 79
    • 58149384269 scopus 로고    scopus 로고
    • Back to the thymus: Peripheral T cells come home
    • Hale, J.S., Fink, P.J., Back to the thymus: Peripheral T cells come home. Immunology and Cell Biology 87:1 (2008), 58–64 http://doi.org/10.1038/icb.2008.87.
    • (2008) Immunology and Cell Biology , vol.87 , Issue.1 , pp. 58-64
    • Hale, J.S.1    Fink, P.J.2
  • 80
    • 77951897845 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin-activated plasmacytoid dendritic cells induce the generation of FOXP3 + regulatory T cells in human thymus
    • Hanabuchi, S., Ito, T., Park, W.-R., Watanabe, N., Shaw, J.L., Roman, E., et al. Thymic stromal lymphopoietin-activated plasmacytoid dendritic cells induce the generation of FOXP3 + regulatory T cells in human thymus. Journal of Immunology (Baltimore, Md.: 1950) 184:6 (2010), 2999–3007 http://doi.org/10.4049/jimmunol.0804106.
    • (2010) Journal of Immunology (Baltimore, Md.: 1950) , vol.184 , Issue.6 , pp. 2999-3007
    • Hanabuchi, S.1    Ito, T.2    Park, W.-R.3    Watanabe, N.4    Shaw, J.L.5    Roman, E.6
  • 81
    • 15744373027 scopus 로고    scopus 로고
    • T-helper type 2 cell-specific expression of the ST2 gene is regulated by transcription factor GATA-3
    • Hayakawa, M., Yanagisawa, K., Aoki, S., Hayakawa, H., Takezako, N., Tominaga, S.-I., T-helper type 2 cell-specific expression of the ST2 gene is regulated by transcription factor GATA-3. Biochimica et Biophysica Acta 1728:1–2 (2005), 53–64 http://doi.org/10.1016/j.bbaexp.2005.01.012.
    • (2005) Biochimica et Biophysica Acta , vol.1728 , Issue.1-2 , pp. 53-64
    • Hayakawa, M.1    Yanagisawa, K.2    Aoki, S.3    Hayakawa, H.4    Takezako, N.5    Tominaga, S.-I.6
  • 82
    • 84865306843 scopus 로고    scopus 로고
    • Properties of end-stage human T cells defined by CD45RA re-expression
    • Henson, S.M., Riddell, N.E., Akbar, A.N., Properties of end-stage human T cells defined by CD45RA re-expression. Current Opinion in Immunology 24:4 (2012), 476–481 http://doi.org/10.1016/j.coi.2012.04.001.
    • (2012) Current Opinion in Immunology , vol.24 , Issue.4 , pp. 476-481
    • Henson, S.M.1    Riddell, N.E.2    Akbar, A.N.3
  • 83
    • 2942692037 scopus 로고    scopus 로고
    • CD4+CD25 + T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion
    • Herman, A.E., Freeman, G.J., Mathis, D., Benoist, C., CD4+CD25 + T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion. Journal of Experimental Medicine 199:11 (2004), 1479–1489 http://doi.org/10.1084/jem.20040179.
    • (2004) Journal of Experimental Medicine , vol.199 , Issue.11 , pp. 1479-1489
    • Herman, A.E.1    Freeman, G.J.2    Mathis, D.3    Benoist, C.4
  • 84
    • 33947631183 scopus 로고    scopus 로고
    • Follicular lymphoma intratumoral CD4+CD25+GITR + regulatory T cells potently suppress CD3/CD28-costimulated autologous and allogeneic CD8+CD25- and CD4+CD25- T cells
    • Hilchey, S.P., De, A., Rimsza, L.M., Bankert, R.B., Bernstein, S.H., Follicular lymphoma intratumoral CD4+CD25+GITR + regulatory T cells potently suppress CD3/CD28-costimulated autologous and allogeneic CD8+CD25- and CD4+CD25- T cells. Journal of Immunology 178:7 (2007), 4051–4061.
    • (2007) Journal of Immunology , vol.178 , Issue.7 , pp. 4051-4061
    • Hilchey, S.P.1    De, A.2    Rimsza, L.M.3    Bankert, R.B.4    Bernstein, S.H.5
  • 85
    • 34548590227 scopus 로고    scopus 로고
    • Foxp3 expression in pancreatic carcinoma cells as a novel mechanism of immune evasion in cancer
    • Hinz, S., Pagerols-Raluy, L., Oberg, H.-H., Ammerpohl, O., Grüssel, S., Sipos, B., et al. Foxp3 expression in pancreatic carcinoma cells as a novel mechanism of immune evasion in cancer. Cancer Research 67:17 (2007), 8344–8350 http://doi.org/10.1158/0008-5472.CAN-06-3304.
    • (2007) Cancer Research , vol.67 , Issue.17 , pp. 8344-8350
    • Hinz, S.1    Pagerols-Raluy, L.2    Oberg, H.-H.3    Ammerpohl, O.4    Grüssel, S.5    Sipos, B.6
  • 86
    • 79959845969 scopus 로고    scopus 로고
    • Regulatory T cells in cutaneous immune responses
    • Honda, T., Miyachi, Y., Kabashima, K., Regulatory T cells in cutaneous immune responses. Journal of Dermatological Science 63:2 (2011), 75–82 http://doi.org/10.1016/j.jdermsci.2011.06.004.
    • (2011) Journal of Dermatological Science , vol.63 , Issue.2 , pp. 75-82
    • Honda, T.1    Miyachi, Y.2    Kabashima, K.3
  • 87
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • Hotamisligil, G.S., Shargill, N.S., Spiegelman, B.M., Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance. Science 259:5091 (1993), 87–91 http://doi.org/10.1126/science.7678183.
    • (1993) Science , vol.259 , Issue.5091 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 88
    • 84862814979 scopus 로고    scopus 로고
    • Selection of regulatory T cells in the thymus
    • Hsieh, C.-S., Lee, H.-M., Lio, C.-W.J., Selection of regulatory T cells in the thymus. Nature Reviews Immunology 12 (2012), 157–167 http://doi.org/10.1038/nri3155.
    • (2012) Nature Reviews Immunology , vol.12 , pp. 157-167
    • Hsieh, C.-S.1    Lee, H.-M.2    Lio, C.-W.J.3
  • 91
    • 0038082377 scopus 로고    scopus 로고
    • Skin-versus gut-skewed homing receptor expression and intrinsic CCR4 expression on human peripheral blood CD4+CD25 + suppressor T cells
    • Iellem, A., Colantonio, L., D'Ambrosio, D., Skin-versus gut-skewed homing receptor expression and intrinsic CCR4 expression on human peripheral blood CD4+CD25 + suppressor T cells. European Journal of Immunology 33:6 (2003), 1488–1496 http://doi.org/10.1002/eji.200323658.
    • (2003) European Journal of Immunology , vol.33 , Issue.6 , pp. 1488-1496
    • Iellem, A.1    Colantonio, L.2    D'Ambrosio, D.3
  • 93
    • 77649145389 scopus 로고    scopus 로고
    • In situ patrolling of regulatory T cells is essential for protecting autoimmune exocrinopathy
    • Ishimaru, N., Nitta, T., Arakaki, R., Yamada, A., Lipp, M., Takahama, Y., et al. In situ patrolling of regulatory T cells is essential for protecting autoimmune exocrinopathy. PLoS One, 5(1), 2010, e8588 http://doi.org/10.1371/journal.pone.0008588.
    • (2010) PLoS One , vol.5 , Issue.1 , pp. e8588
    • Ishimaru, N.1    Nitta, T.2    Arakaki, R.3    Yamada, A.4    Lipp, M.5    Takahama, Y.6
  • 94
    • 0033136302 scopus 로고    scopus 로고
    • Thymus and autoimmunity: Production of CD25+CD4 + naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
    • Itoh, M., Takahashi, T., Sakaguchi, N., Kuniyasu, Y., Shimizu, J., Otsuka, F., et al. Thymus and autoimmunity: Production of CD25+CD4 + naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. Journal of Immunology (Baltimore, Md.: 1950) 162:9 (1999), 5317–5326.
    • (1999) Journal of Immunology (Baltimore, Md.: 1950) , vol.162 , Issue.9 , pp. 5317-5326
    • Itoh, M.1    Takahashi, T.2    Sakaguchi, N.3    Kuniyasu, Y.4    Shimizu, J.5    Otsuka, F.6
  • 95
    • 78650663108 scopus 로고    scopus 로고
    • The protein tyrosine phosphatase SHP-1 modulates the suppressive activity of regulatory T cells
    • Iype, T., Sankarshanan, M., Mauldin, I.S., Mullins, D.W., Lorenz, U., The protein tyrosine phosphatase SHP-1 modulates the suppressive activity of regulatory T cells. Journal of Immunology (Baltimore, Md.: 1950) 185:10 (2010), 6115–6127 http://doi.org/10.4049/jimmunol.1000622.
    • (2010) Journal of Immunology (Baltimore, Md.: 1950) , vol.185 , Issue.10 , pp. 6115-6127
    • Iype, T.1    Sankarshanan, M.2    Mauldin, I.S.3    Mullins, D.W.4    Lorenz, U.5
  • 96
    • 33847144180 scopus 로고    scopus 로고
    • Conventional T-bet+Foxp3 − Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection
    • Jankovic, D., Kullberg, M.C., Feng, C.G., Goldszmid, R.S., Collazo, C.M., Wilson, M., et al. Conventional T-bet+Foxp3 − Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. The Journal of Experimental Medicine 204:2 (2007), 273–283 http://doi.org/10.1084/jem.20062175.
    • (2007) The Journal of Experimental Medicine , vol.204 , Issue.2 , pp. 273-283
    • Jankovic, D.1    Kullberg, M.C.2    Feng, C.G.3    Goldszmid, R.S.4    Collazo, C.M.5    Wilson, M.6
  • 97
    • 84887832812 scopus 로고    scopus 로고
    • Intratumoral regulatory T cells upregulate immunosuppressive molecules in head and neck cancer patients
    • Jie, H.-B., Gildener-Leapman, N., Li, J., Srivastava, R.M., Gibson, S.P., Whiteside, T.L., et al. Intratumoral regulatory T cells upregulate immunosuppressive molecules in head and neck cancer patients. British Journal of Cancer 109:10 (2013), 2629–2635 http://doi.org/10.1038/bjc.2013.645.
    • (2013) British Journal of Cancer , vol.109 , Issue.10 , pp. 2629-2635
    • Jie, H.-B.1    Gildener-Leapman, N.2    Li, J.3    Srivastava, R.M.4    Gibson, S.P.5    Whiteside, T.L.6
  • 98
    • 33846513614 scopus 로고    scopus 로고
    • Naturally occurring lung CD4(+)CD25(+) T cell regulation of airway allergic responses depends on IL-10 induction of TGF-beta
    • Joetham, A., Takeda, K., Taube, C., Miyahara, N., Matsubara, S., Koya, T., et al. Naturally occurring lung CD4(+)CD25(+) T cell regulation of airway allergic responses depends on IL-10 induction of TGF-beta. Journal of Immunology (Baltimore, Md.: 1950) 178:3 (2007), 1433–1442.
    • (2007) Journal of Immunology (Baltimore, Md.: 1950) , vol.178 , Issue.3 , pp. 1433-1442
    • Joetham, A.1    Takeda, K.2    Taube, C.3    Miyahara, N.4    Matsubara, S.5    Koya, T.6
  • 99
    • 84898681799 scopus 로고    scopus 로고
    • Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses
    • Joller, N., Lozano, E., Burkett, P.R., Patel, B., Xiao, S., Zhu, C., et al. Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses. Immunity 40:4 (2014), 569–581 http://doi.org/10.1016/j.immuni.2014.02.012.
    • (2014) Immunity , vol.40 , Issue.4 , pp. 569-581
    • Joller, N.1    Lozano, E.2    Burkett, P.R.3    Patel, B.4    Xiao, S.5    Zhu, C.6
  • 100
    • 0035806290 scopus 로고    scopus 로고
    • Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood
    • Jonuleit, H., Schmitt, E., Stassen, M., Tuettenberg, A., Knop, J., Enk, A.H., Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. The Journal of Experimental Medicine 193:11 (2001), 1285–1294.
    • (2001) The Journal of Experimental Medicine , vol.193 , Issue.11 , pp. 1285-1294
    • Jonuleit, H.1    Schmitt, E.2    Stassen, M.3    Tuettenberg, A.4    Knop, J.5    Enk, A.H.6
  • 102
    • 84859416933 scopus 로고    scopus 로고
    • Regulatory T cells: Mechanisms of differentiation and function
    • Josefowicz, S.Z., Lu, L.-F., Rudensky, A.Y., Regulatory T cells: Mechanisms of differentiation and function. Annual Review of Immunology 30 (2012), 531–564 http://doi.org/10.1146/annurev.immunol.25.022106.141623.
    • (2012) Annual Review of Immunology , vol.30 , pp. 531-564
    • Josefowicz, S.Z.1    Lu, L.-F.2    Rudensky, A.Y.3
  • 103
    • 84862777225 scopus 로고    scopus 로고
    • Extrathymically generated regulatory T cells control mucosal TH2 inflammation
    • Josefowicz, S.Z., Niec, R.E., Kim, H.Y., Treuting, P., Chinen, T., Zheng, Y., et al. Extrathymically generated regulatory T cells control mucosal TH2 inflammation. Nature 482:7385 (2012), 395–399 http://doi.org/10.1038/nature10772.
    • (2012) Nature , vol.482 , Issue.7385 , pp. 395-399
    • Josefowicz, S.Z.1    Niec, R.E.2    Kim, H.Y.3    Treuting, P.4    Chinen, T.5    Zheng, Y.6
  • 105
    • 80051621753 scopus 로고    scopus 로고
    • Obstructive jaundice expands intrahepatic regulatory T cells, which impair liver T lymphocyte function but modulate liver cholestasis and fibrosis
    • Katz, S.C., Ryan, K., Ahmed, N., Plitas, G., Chaudhry, U.I., Kingham, T.P., et al. Obstructive jaundice expands intrahepatic regulatory T cells, which impair liver T lymphocyte function but modulate liver cholestasis and fibrosis. Journal of Immunology (Baltimore, Md.: 1950) 187:3 (2011), 1150–1156 http://doi.org/10.4049/jimmunol.1004077.
    • (2011) Journal of Immunology (Baltimore, Md.: 1950) , vol.187 , Issue.3 , pp. 1150-1156
    • Katz, S.C.1    Ryan, K.2    Ahmed, N.3    Plitas, G.4    Chaudhry, U.I.5    Kingham, T.P.6
  • 106
    • 50649121609 scopus 로고    scopus 로고
    • CD4(+)CD25(+) regulatory T cells reverse established allergic airway inflammation and prevent airway remodeling
    • Kearley, J., Robinson, D.S., Lloyd, C.M., CD4(+)CD25(+) regulatory T cells reverse established allergic airway inflammation and prevent airway remodeling. The Journal of Allergy and Clinical Immunology 122 (2008), 617–624.
    • (2008) The Journal of Allergy and Clinical Immunology , vol.122 , pp. 617-624
    • Kearley, J.1    Robinson, D.S.2    Lloyd, C.M.3
  • 107
    • 84958910139 scopus 로고    scopus 로고
    • Dietary antigens limit mucosal immunity by inducing regulatory T cells in the small intestine
    • aac5560
    • Kim, K.S., Hong, S.-W., Han, D., Yi, J., Jung, J., Yang, B.-G., et al. Dietary antigens limit mucosal immunity by inducing regulatory T cells in the small intestine. Science 351 (2016), 858–863 aac5560 http://doi.org/10.1126/science.aac5560.
    • (2016) Science , vol.351 , pp. 858-863
    • Kim, K.S.1    Hong, S.-W.2    Han, D.3    Yi, J.4    Jung, J.5    Yang, B.-G.6
  • 108
    • 0036467522 scopus 로고    scopus 로고
    • CD25+CD4 + regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses
    • Kingsley, C.I., Karim, M., Bushell, A.R., Wood, K.J., CD25+CD4 + regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. Journal of Immunology 168:3 (2002), 1080–1086 http://doi.org/10.4049/jimmunol.168.3.1080.
    • (2002) Journal of Immunology , vol.168 , Issue.3 , pp. 1080-1086
    • Kingsley, C.I.1    Karim, M.2    Bushell, A.R.3    Wood, K.J.4
  • 109
    • 78049276260 scopus 로고    scopus 로고
    • Selective depletion of Foxp3 + regulatory T cells improves effective therapeutic vaccination against established melanoma
    • Klages, K., Mayer, C.T., Lahl, K., Loddenkemper, C., Teng, M.W.L., Ngiow, S.F., et al. Selective depletion of Foxp3 + regulatory T cells improves effective therapeutic vaccination against established melanoma. Cancer Research 70:20 (2010), 7788–7799 http://doi.org/10.1158/0008-5472.CAN-10-1736.
    • (2010) Cancer Research , vol.70 , Issue.20 , pp. 7788-7799
    • Klages, K.1    Mayer, C.T.2    Lahl, K.3    Loddenkemper, C.4    Teng, M.W.L.5    Ngiow, S.F.6
  • 110
    • 15944425718 scopus 로고    scopus 로고
    • CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4 + T-cell subset
    • Kleinewietfeld, M., Puentes, F., Borsellino, G., Battistini, L., Rötzschke, O., Falk, K., CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4 + T-cell subset. Blood 105:7 (2005), 2877–2886 http://doi.org/10.1182/blood-2004-07-2505.
    • (2005) Blood , vol.105 , Issue.7 , pp. 2877-2886
    • Kleinewietfeld, M.1    Puentes, F.2    Borsellino, G.3    Battistini, L.4    Rötzschke, O.5    Falk, K.6
  • 111
    • 59649091305 scopus 로고    scopus 로고
    • CD49d provides access to “untouched” human Foxp3 + Treg free of contaminating effector cells
    • Kleinewietfeld, M., Starke, M., Di Mitri, D., Borsellino, G., Battistini, L., Rotzschke, O., et al. CD49d provides access to “untouched” human Foxp3 + Treg free of contaminating effector cells. Blood 113:4 (2009), 827–836 http://doi.org/10.1182/blood-2008-04-150524.
    • (2009) Blood , vol.113 , Issue.4 , pp. 827-836
    • Kleinewietfeld, M.1    Starke, M.2    Di Mitri, D.3    Borsellino, G.4    Battistini, L.5    Rotzschke, O.6
  • 112
    • 84873019070 scopus 로고    scopus 로고
    • Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature
    • Kleinschnitz, C., Kraft, P., Dreykluft, A., Hagedorn, I., Göbel, K., Schuhmann, M.K., et al. Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature. Blood 121:4 (2013), 679–691 http://doi.org/10.1182/blood-2012-04-426734.
    • (2013) Blood , vol.121 , Issue.4 , pp. 679-691
    • Kleinschnitz, C.1    Kraft, P.2    Dreykluft, A.3    Hagedorn, I.4    Göbel, K.5    Schuhmann, M.K.6
  • 114
    • 33750832563 scopus 로고    scopus 로고
    • T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5′-adenosine monophosphate to adenosine
    • Kobie, J.J., Shah, P.R., Yang, L., Rebhahn, J.A., Fowell, D.J., Mosmann, T.R., T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5′-adenosine monophosphate to adenosine. Journal of Immunology (Baltimore, Md.: 1950) 177:10 (2006), 6780–6786.
    • (2006) Journal of Immunology (Baltimore, Md.: 1950) , vol.177 , Issue.10 , pp. 6780-6786
    • Kobie, J.J.1    Shah, P.R.2    Yang, L.3    Rebhahn, J.A.4    Fowell, D.J.5    Mosmann, T.R.6
  • 115
    • 78249249625 scopus 로고    scopus 로고
    • Interleukin-33 expression is specifically enhanced in inflamed mucosa of ulcerative colitis
    • Kobori, A., Yagi, Y., Imaeda, H., Ban, H., Bamba, S., Tsujikawa, T., et al. Interleukin-33 expression is specifically enhanced in inflamed mucosa of ulcerative colitis. Journal of Gastroenterology 45:10 (2010), 999–1007 http://doi.org/10.1007/s00535-010-0245-1.
    • (2010) Journal of Gastroenterology , vol.45 , Issue.10 , pp. 999-1007
    • Kobori, A.1    Yagi, Y.2    Imaeda, H.3    Ban, H.4    Bamba, S.5    Tsujikawa, T.6
  • 116
    • 65749103365 scopus 로고    scopus 로고
    • The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
    • Koch, M.A., Tucker-Heard, G., Perdue, N.R., Killebrew, J.R., Urdahl, K.B., Campbell, D.J., The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation. Nature Immunology 10:6 (2009), 595–602 http://doi.org/10.1038/ni.1731.
    • (2009) Nature Immunology , vol.10 , Issue.6 , pp. 595-602
    • Koch, M.A.1    Tucker-Heard, G.2    Perdue, N.R.3    Killebrew, J.R.4    Urdahl, K.B.5    Campbell, D.J.6
  • 117
    • 84928407438 scopus 로고    scopus 로고
    • Antigen- and cytokine-driven accumulation of regulatory T cells in visceral adipose tissue of lean mice
    • Kolodin, D., van Panhuys, N., Li, C., Magnuson, A.M., Cipolletta, D., Miller, C.M., et al. Antigen- and cytokine-driven accumulation of regulatory T cells in visceral adipose tissue of lean mice. Cell Metabolism 21:4 (2015), 543–557 http://doi.org/10.1016/j.cmet.2015.03.005.
    • (2015) Cell Metabolism , vol.21 , Issue.4 , pp. 543-557
    • Kolodin, D.1    van Panhuys, N.2    Li, C.3    Magnuson, A.M.4    Cipolletta, D.5    Miller, C.M.6
  • 118
    • 0024405828 scopus 로고
    • The T-cell receptor repertoire and autoimmune diseases
    • Kumar, V., Kono, D.H., Urban, J.L., Hood, L., The T-cell receptor repertoire and autoimmune diseases. Annual Review of Immunology 7:1 (1989), 657–682 http://doi.org/10.1146/annurev.iy.07.040189.003301.
    • (1989) Annual Review of Immunology , vol.7 , Issue.1 , pp. 657-682
    • Kumar, V.1    Kono, D.H.2    Urban, J.L.3    Hood, L.4
  • 119
    • 0031985157 scopus 로고    scopus 로고
    • Association of tyrosine phosphatases SHP-1 and SHP-2, inositol 5-phosphatase SHIP with gp49B1, and chromosomal assignment of the gene
    • Kuroiwa, A., Yamashita, Y., Inui, M., Yuasa, T., Ono, M., Nagabukuro, A., et al. Association of tyrosine phosphatases SHP-1 and SHP-2, inositol 5-phosphatase SHIP with gp49B1, and chromosomal assignment of the gene. The Journal of Biological Chemistry 273:2 (1998), 1070–1074.
    • (1998) The Journal of Biological Chemistry , vol.273 , Issue.2 , pp. 1070-1074
    • Kuroiwa, A.1    Yamashita, Y.2    Inui, M.3    Yuasa, T.4    Ono, M.5    Nagabukuro, A.6
  • 120
    • 33847344205 scopus 로고    scopus 로고
    • Cutting edge: Regulatory T cells prevent efficient clearance of Mycobacterium tuberculosis
    • Kursar, M., Koch, M., Mittrücker, H.-W., Nouailles, G., Bonhagen, K., Kamradt, T., et al. Cutting edge: Regulatory T cells prevent efficient clearance of Mycobacterium tuberculosis. Journal of Immunology 178:5 (2007), 2661–2665 http://doi.org/10.4049/jimmunol.178.5.2661.
    • (2007) Journal of Immunology , vol.178 , Issue.5 , pp. 2661-2665
    • Kursar, M.1    Koch, M.2    Mittrücker, H.-W.3    Nouailles, G.4    Bonhagen, K.5    Kamradt, T.6
  • 121
    • 84956705644 scopus 로고    scopus 로고
    • Poor repair of skeletal muscle in aging mice reflects a defect in local, interleukin-33-dependent accumulation of regulatory T cells
    • Kuswanto, W., Burzyn, D., Panduro, M., Wang, K.K., Jang, Y.C., Wagers, A.J., et al. Poor repair of skeletal muscle in aging mice reflects a defect in local, interleukin-33-dependent accumulation of regulatory T cells. Immunity 44:2 (2016), 355–367 http://doi.org/10.1016/j.immuni.2016.01.009.
    • (2016) Immunity , vol.44 , Issue.2 , pp. 355-367
    • Kuswanto, W.1    Burzyn, D.2    Panduro, M.3    Wang, K.K.4    Jang, Y.C.5    Wagers, A.J.6
  • 122
    • 79959742164 scopus 로고    scopus 로고
    • Prognostic role of FOXP3 + regulatory T cells infiltrating human carcinomas: The paradox of colorectal cancer
    • Ladoire, S., Martin, F., Ghiringhelli, F., Prognostic role of FOXP3 + regulatory T cells infiltrating human carcinomas: The paradox of colorectal cancer. Cancer Immunology, Immunotherapy 60:7 (2011), 909–918 http://doi.org/10.1007/s00262-011-1046-y.
    • (2011) Cancer Immunology, Immunotherapy , vol.60 , Issue.7 , pp. 909-918
    • Ladoire, S.1    Martin, F.2    Ghiringhelli, F.3
  • 123
    • 0028102655 scopus 로고
    • High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice
    • Lafaille, J.J., Nagashima, K., Katsuki, M., Tonegawa, S., High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell 78:3 (1994), 399–408 http://doi.org/10.1016/0092-8674(94)90419-7.
    • (1994) Cell , vol.78 , Issue.3 , pp. 399-408
    • Lafaille, J.J.1    Nagashima, K.2    Katsuki, M.3    Tonegawa, S.4
  • 124
    • 77954166341 scopus 로고    scopus 로고
    • Nonfunctional regulatory T cells and defective control of Th2 cytokine production in natural scurfy mutant mice
    • Lahl, K., Mayer, C.T., Bopp, T., Huehn, J., Loddenkemper, C., Eberl, G., et al. Nonfunctional regulatory T cells and defective control of Th2 cytokine production in natural scurfy mutant mice. Journal of Immunology (Baltimore, Md.: 1950) 183:9 (2009), 5662–5672 http://doi.org/10.4049/jimmunol.0803762.
    • (2009) Journal of Immunology (Baltimore, Md.: 1950) , vol.183 , Issue.9 , pp. 5662-5672
    • Lahl, K.1    Mayer, C.T.2    Bopp, T.3    Huehn, J.4    Loddenkemper, C.5    Eberl, G.6
  • 125
    • 58149252418 scopus 로고    scopus 로고
    • Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation
    • Li, Q., Guo, Z., Xu, X., Xia, S., Cao, X., Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation. European Journal of Immunology 38:10 (2008), 2751–2761 http://doi.org/10.1002/eji.200838542.
    • (2008) European Journal of Immunology , vol.38 , Issue.10 , pp. 2751-2761
    • Li, Q.1    Guo, Z.2    Xu, X.3    Xia, S.4    Cao, X.5
  • 126
    • 78649557780 scopus 로고    scopus 로고
    • Efficient Treg depletion induces T-cell infiltration and rejection of large tumors
    • Li, X., Kostareli, E., Suffner, J., Garbi, N., Hämmerling, G.J., Efficient Treg depletion induces T-cell infiltration and rejection of large tumors. European Journal of Immunology 40:12 (2010), 3325–3335 http://doi.org/10.1002/eji.201041093.
    • (2010) European Journal of Immunology , vol.40 , Issue.12 , pp. 3325-3335
    • Li, X.1    Kostareli, E.2    Suffner, J.3    Garbi, N.4    Hämmerling, G.J.5
  • 127
    • 34248592104 scopus 로고    scopus 로고
    • T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation
    • Li, M.O., Wan, Y.Y., Flavell, R.A., T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation. Immunity 26:5 (2007), 579–591 http://doi.org/10.1016/j.immuni.2007.03.014.
    • (2007) Immunity , vol.26 , Issue.5 , pp. 579-591
    • Li, M.O.1    Wan, Y.Y.2    Flavell, R.A.3
  • 128
    • 44449110691 scopus 로고    scopus 로고
    • Regulatory T cells inhibit dendritic cells by lymphocyte activation gene-3 engagement of MHC class II
    • Liang, B., Workman, C., Lee, J., Chew, C., Dale, B.M., Colonna, L., et al. Regulatory T cells inhibit dendritic cells by lymphocyte activation gene-3 engagement of MHC class II. Journal of Immunology 180:9 (2008), 5916–5926 http://doi.org/10.4049/jimmunol.180.9.5916.
    • (2008) Journal of Immunology , vol.180 , Issue.9 , pp. 5916-5926
    • Liang, B.1    Workman, C.2    Lee, J.3    Chew, C.4    Dale, B.M.5    Colonna, L.6
  • 129
    • 59649123881 scopus 로고    scopus 로고
    • Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke
    • Liesz, A., Suri-Payer, E., Veltkamp, C., Doerr, H., Sommer, C., Rivest, S., et al. Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke. Nature Medicine 15:2 (2009), 192–199 http://doi.org/10.1038/nm.1927.
    • (2009) Nature Medicine , vol.15 , Issue.2 , pp. 192-199
    • Liesz, A.1    Suri-Payer, E.2    Veltkamp, C.3    Doerr, H.4    Sommer, C.5    Rivest, S.6
  • 130
    • 84959418975 scopus 로고    scopus 로고
    • Increased generation of Foxp3 + regulatory T cells by manipulating antigen presentation in the thymus
    • Lin, J., Yang, L., Silva, H.M., Trzeciak, A., Choi, Y., Schwab, S.R., et al. Increased generation of Foxp3 + regulatory T cells by manipulating antigen presentation in the thymus. Nature Communications, 7, 2016, 10562 http://doi.org/10.1038/ncomms10562.
    • (2016) Nature Communications , vol.7 , pp. 10562
    • Lin, J.1    Yang, L.2    Silva, H.M.3    Trzeciak, A.4    Choi, Y.5    Schwab, S.R.6
  • 131
    • 0036721629 scopus 로고    scopus 로고
    • Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
    • Liyanage, U.K., Moore, T.T., Joo, H.-G., Tanaka, Y., Herrmann, V., Doherty, G., et al. Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. Journal of Immunology 169:5 (2002), 2756–2761 http://doi.org/10.4049/jimmunol.169.5.2756.
    • (2002) Journal of Immunology , vol.169 , Issue.5 , pp. 2756-2761
    • Liyanage, U.K.1    Moore, T.T.2    Joo, H.-G.3    Tanaka, Y.4    Herrmann, V.5    Doherty, G.6
  • 132
    • 70049094943 scopus 로고    scopus 로고
    • Regulatory T cells in asthma
    • Lloyd, C.M., Hawrylowicz, C.M., Regulatory T cells in asthma. Immunity 31:3 (2009), 438–449 http://doi.org/10.1016/j.immuni.2009.08.007.
    • (2009) Immunity , vol.31 , Issue.3 , pp. 438-449
    • Lloyd, C.M.1    Hawrylowicz, C.M.2
  • 134
    • 34250813631 scopus 로고    scopus 로고
    • IL-10 controls ultraviolet-induced carcinogenesis in mice
    • Loser, K., Apelt, J., Voskort, M., Mohaupt, M., Balkow, S., Schwarz, T., et al. IL-10 controls ultraviolet-induced carcinogenesis in mice. Journal of Immunology 179:1 (2007), 365–371 http://doi.org/10.4049/jimmunol.179.1.365.
    • (2007) Journal of Immunology , vol.179 , Issue.1 , pp. 365-371
    • Loser, K.1    Apelt, J.2    Voskort, M.3    Mohaupt, M.4    Balkow, S.5    Schwarz, T.6
  • 135
    • 0033605258 scopus 로고    scopus 로고
    • gp49B1 inhibits IgE-initiated mast cell activation through both immunoreceptor tyrosine-based inhibitory motifs, recruitment of src homology 2 domain-containing phosphatase-1, and suppression of early and late calcium mobilization
    • Lu-Kuo, J.M., Joyal, D.M., Austen, K.F., Katz, H.R., gp49B1 inhibits IgE-initiated mast cell activation through both immunoreceptor tyrosine-based inhibitory motifs, recruitment of src homology 2 domain-containing phosphatase-1, and suppression of early and late calcium mobilization. The Journal of Biological Chemistry 274:9 (1999), 5791–5796 http://doi.org/10.1074/jbc.274.9.5791.
    • (1999) The Journal of Biological Chemistry , vol.274 , Issue.9 , pp. 5791-5796
    • Lu-Kuo, J.M.1    Joyal, D.M.2    Austen, K.F.3    Katz, H.R.4
  • 137
    • 33947283177 scopus 로고    scopus 로고
    • B cell regulation of CD4+CD25 + T regulatory cells and IL-10 via B7 is essential for recovery from experimental autoimmune encephalomyelitis
    • Mann, M.K., Maresz, K., Shriver, L.P., Tan, Y., Dittel, B.N., B cell regulation of CD4+CD25 + T regulatory cells and IL-10 via B7 is essential for recovery from experimental autoimmune encephalomyelitis. Journal of Immunology 178:6 (2007), 3447–3456 http://doi.org/10.4049/jimmunol.178.6.3447.
    • (2007) Journal of Immunology , vol.178 , Issue.6 , pp. 3447-3456
    • Mann, M.K.1    Maresz, K.2    Shriver, L.P.3    Tan, Y.4    Dittel, B.N.5
  • 138
    • 60149101114 scopus 로고    scopus 로고
    • Dendritic cell antigen presentation drives simultaneous cytokine production by effector and regulatory T cells in inflamed skin
    • Mclachlan, J.B., Catron, D.M., Moon, J.J., Jenkins, M.K., Dendritic cell antigen presentation drives simultaneous cytokine production by effector and regulatory T cells in inflamed skin. Immunity 30:2 (2009), 277–288 http://doi.org/10.1016/j.immuni.2008.11.013.
    • (2009) Immunity , vol.30 , Issue.2 , pp. 277-288
    • Mclachlan, J.B.1    Catron, D.M.2    Moon, J.J.3    Jenkins, M.K.4
  • 139
    • 5044220930 scopus 로고    scopus 로고
    • Ido expression by dendritic cells: Tolerance and tryptophan catabolism
    • Mellor, A.L., Munn, D.H., Ido expression by dendritic cells: Tolerance and tryptophan catabolism. Nature Reviews. Immunology 4:10 (2004), 762–774 http://doi.org/10.1038/nri1457.
    • (2004) Nature Reviews. Immunology , vol.4 , Issue.10 , pp. 762-774
    • Mellor, A.L.1    Munn, D.H.2
  • 140
    • 77649213110 scopus 로고    scopus 로고
    • Expression and function of TNF and IL-1 receptors on human regulatory T cells
    • Mercer, F., Kozhaya, L., Unutmaz, D., Expression and function of TNF and IL-1 receptors on human regulatory T cells. PLoS One, 5(1), 2010, e8639 http://doi.org/10.1371/journal.pone.0008639.
    • (2010) PLoS One , vol.5 , Issue.1 , pp. e8639
    • Mercer, F.1    Kozhaya, L.2    Unutmaz, D.3
  • 141
    • 49749221890 scopus 로고
    • Immunological function of the thymus
    • Miller, J.F.A.P., Immunological function of the thymus. Lancet 278:7205 (1961), 748–749 http://doi.org/10.1016/S0140-6736(61)90693-6.
    • (1961) Lancet , vol.278 , Issue.7205 , pp. 748-749
    • Miller, J.F.A.P.1
  • 142
    • 0000664461 scopus 로고
    • Immunological significance of the thymus of the adult mouse
    • Miller, J.F.A.P., Immunological significance of the thymus of the adult mouse. Nature 195:4848 (1962), 1318–1319 http://doi.org/10.1038/1951318a0.
    • (1962) Nature , vol.195 , Issue.4848 , pp. 1318-1319
    • Miller, J.F.A.P.1
  • 143
    • 0036630810 scopus 로고    scopus 로고
    • The discovery of thymus function and of thymus-derived lymphocytes
    • Miller, J.F.A.P., The discovery of thymus function and of thymus-derived lymphocytes. Immunological Reviews 185:1 (2002), 7–14 http://doi.org/10.1034/j.1600-065X.2002.18502.x.
    • (2002) Immunological Reviews , vol.185 , Issue.1 , pp. 7-14
    • Miller, J.F.A.P.1
  • 144
    • 0014347838 scopus 로고
    • Cell to cell interaction in the immune response. I. Hemolysin-forming cells in neonatally thymectomized mice reconstituted with thymus or thoracic duct lymphocyte
    • Miller, J.F., Mitchell, G.F., Cell to cell interaction in the immune response. I. Hemolysin-forming cells in neonatally thymectomized mice reconstituted with thymus or thoracic duct lymphocyte. Journal of Experimental Medicine 128:4 (1968), 801–820.
    • (1968) Journal of Experimental Medicine , vol.128 , Issue.4 , pp. 801-820
    • Miller, J.F.1    Mitchell, G.F.2
  • 146
    • 84881356321 scopus 로고    scopus 로고
    • AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration
    • Mounier, R., Théret, M., Arnold, L., Cuvellier, S., Bultot, L., Göransson, O., et al. AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration. Cell Metabolism 18:2 (2013), 251–264 http://doi.org/10.1016/j.cmet.2013.06.017.
    • (2013) Cell Metabolism , vol.18 , Issue.2 , pp. 251-264
    • Mounier, R.1    Théret, M.2    Arnold, L.3    Cuvellier, S.4    Bultot, L.5    Göransson, O.6
  • 147
    • 0035801335 scopus 로고    scopus 로고
    • Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
    • Nakamura, K., Kitani, A., Strober, W., Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. The Journal of Experimental Medicine 194:5 (2001), 629–644.
    • (2001) The Journal of Experimental Medicine , vol.194 , Issue.5 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 148
    • 84884561907 scopus 로고    scopus 로고
    • Molecular pathways: Coexpression of immune checkpoint molecules: Signaling pathways and implications for cancer immunotherapy
    • Nirschl, C.J., Drake, C.G., Molecular pathways: Coexpression of immune checkpoint molecules: Signaling pathways and implications for cancer immunotherapy. Clinical Cancer Research 19:18 (2013), 4917–4924 http://doi.org/10.1158/1078-0432.CCR-12-1972.
    • (2013) Clinical Cancer Research , vol.19 , Issue.18 , pp. 4917-4924
    • Nirschl, C.J.1    Drake, C.G.2
  • 149
    • 0014667395 scopus 로고
    • Thymus and reproduction: Sex-linked dysgenesia of the gonad after neonatal thymectomy in mice
    • Nishizuka, Y., Sakakura, T., Thymus and reproduction: Sex-linked dysgenesia of the gonad after neonatal thymectomy in mice. Science 166:3906 (1969), 753–755.
    • (1969) Science , vol.166 , Issue.3906 , pp. 753-755
    • Nishizuka, Y.1    Sakakura, T.2
  • 150
    • 35748965021 scopus 로고    scopus 로고
    • Rapid suppression of cytokine transcription in human CD4+CD25 T cells by CD4+Foxp3 + regulatory T cells: Independence of IL-2 consumption, TGF-beta, and various inhibitors of TCR signaling
    • Oberle, N., Eberhardt, N., Falk, C.S., Krammer, P.H., Suri-Payer, E., Rapid suppression of cytokine transcription in human CD4+CD25 T cells by CD4+Foxp3 + regulatory T cells: Independence of IL-2 consumption, TGF-beta, and various inhibitors of TCR signaling. Journal of Immunology 179:6 (2007), 3578–3587 http://doi.org/10.4049/jimmunol.179.6.3578.
    • (2007) Journal of Immunology , vol.179 , Issue.6 , pp. 3578-3587
    • Oberle, N.1    Eberhardt, N.2    Falk, C.S.3    Krammer, P.H.4    Suri-Payer, E.5
  • 151
    • 84940547063 scopus 로고    scopus 로고
    • The microbiota regulates type 2 immunity through RORγt + T cells
    • aac4263
    • Ohnmacht, C., Park, J.-H., Cording, S., Wing, J.B., Atarashi, K., Obata, Y., et al. The microbiota regulates type 2 immunity through RORγt + T cells. Science 349 (2015), 989–993 aac4263 http://doi.org/10.1126/science.aac4263.
    • (2015) Science , vol.349 , pp. 989-993
    • Ohnmacht, C.1    Park, J.-H.2    Cording, S.3    Wing, J.B.4    Atarashi, K.5    Obata, Y.6
  • 152
    • 0032538918 scopus 로고    scopus 로고
    • Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis
    • Olivares-Villagómez, D., Wang, Y., Lafaille, J.J., Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis. Journal of Experimental Medicine 188:10 (1998), 1883–1894 http://doi.org/10.1084/jem.188.10.1883.
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.10 , pp. 1883-1894
    • Olivares-Villagómez, D.1    Wang, Y.2    Lafaille, J.J.3
  • 153
    • 48249103057 scopus 로고    scopus 로고
    • Foxp3 + natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation
    • Onishi, Y., Fehervari, Z., Yamaguchi, T., Sakaguchi, S., Foxp3 + natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation. Proceedings of the National Academy of Sciences of the United States of America 105:29 (2008), 10113–10118 http://doi.org/10.1073/pnas.0711106105.
    • (2008) Proceedings of the National Academy of Sciences of the United States of America , vol.105 , Issue.29 , pp. 10113-10118
    • Onishi, Y.1    Fehervari, Z.2    Yamaguchi, T.3    Sakaguchi, S.4
  • 155
    • 36248976097 scopus 로고    scopus 로고
    • CD4+CD25+Foxp3 + regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4 + T cells
    • Pandiyan, P., Zheng, L., Ishihara, S., Reed, J., Lenardo, M.J., CD4+CD25+Foxp3 + regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4 + T cells. Nature Immunology 8:12 (2007), 1353–1362 http://doi.org/10.1038/ni1536.
    • (2007) Nature Immunology , vol.8 , Issue.12 , pp. 1353-1362
    • Pandiyan, P.1    Zheng, L.2    Ishihara, S.3    Reed, J.4    Lenardo, M.J.5
  • 156
    • 78650209225 scopus 로고    scopus 로고
    • T regulatory cells maintain intestinal homeostasis by suppressing γδ T cells
    • Park, S.-G., Mathur, R., Long, M., Hosh, N., Hao, L., Hayden, M.S., et al. T regulatory cells maintain intestinal homeostasis by suppressing γδ T cells. Immunity 33:5 (2010), 791–803 http://doi.org/10.1016/j.immuni.2010.10.014.
    • (2010) Immunity , vol.33 , Issue.5 , pp. 791-803
    • Park, S.-G.1    Mathur, R.2    Long, M.3    Hosh, N.4    Hao, L.5    Hayden, M.S.6
  • 158
    • 84977919613 scopus 로고    scopus 로고
    • Low-grade inflammation, obesity, and diabetes
    • Pereira, S.S., Alvarez-Leite, J.I., Low-grade inflammation, obesity, and diabetes. Current Obesity Reports 3:4 (2014), 422–431 http://doi.org/10.1007/s13679-014-0124-9.
    • (2014) Current Obesity Reports , vol.3 , Issue.4 , pp. 422-431
    • Pereira, S.S.1    Alvarez-Leite, J.I.2
  • 159
    • 84963533918 scopus 로고    scopus 로고
    • Development of T-cell tolerance utilizes both cell-autonomous and cooperative presentation of self-antigen
    • Perry, J.S.A., Hsieh, C.-S., Development of T-cell tolerance utilizes both cell-autonomous and cooperative presentation of self-antigen. Immunological Reviews 271:1 (2016), 141–155 http://doi.org/10.1111/imr.12403.
    • (2016) Immunological Reviews , vol.271 , Issue.1 , pp. 141-155
    • Perry, J.S.A.1    Hsieh, C.-S.2
  • 160
    • 84887338659 scopus 로고    scopus 로고
    • Human secondary lymphoid organs typically contain polyclonally-activated proliferating regulatory T cells
    • Peters, J.H., Koenen, H.J.P.M., Fasse, E., Tijssen, H.J., IJzermans, J.N.M., Groenen, P.J.T.A., et al. Human secondary lymphoid organs typically contain polyclonally-activated proliferating regulatory T cells. Blood 122:13 (2013), 2213–2223 http://doi.org/10.1182/blood-2013-03-489443.
    • (2013) Blood , vol.122 , Issue.13 , pp. 2213-2223
    • Peters, J.H.1    Koenen, H.J.P.M.2    Fasse, E.3    Tijssen, H.J.4    IJzermans, J.N.M.5    Groenen, P.J.T.A.6
  • 161
    • 0037099613 scopus 로고    scopus 로고
    • CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness
    • Piccirillo, C.A., Letterio, J.J., Thornton, A.M., McHugh, R.S., Mamura, M., Mizuhara, H., et al. CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness. The Journal of Experimental Medicine 196:2 (2002), 237–246.
    • (2002) The Journal of Experimental Medicine , vol.196 , Issue.2 , pp. 237-246
    • Piccirillo, C.A.1    Letterio, J.J.2    Thornton, A.M.3    McHugh, R.S.4    Mamura, M.5    Mizuhara, H.6
  • 162
    • 84859378165 scopus 로고    scopus 로고
    • Endogenous IL-33 is highly expressed in mouse epithelial barrier tissues, lymphoid organs, brain, embryos, and inflamed tissues: In situ analysis using a novel Il-33-LacZ gene trap reporter strain
    • Pichery, M., Mirey, E., Mercier, P., Lefrancais, E., Dujardin, A., Ortega, N., et al. Endogenous IL-33 is highly expressed in mouse epithelial barrier tissues, lymphoid organs, brain, embryos, and inflamed tissues: In situ analysis using a novel Il-33-LacZ gene trap reporter strain. Journal of Immunology (Baltimore, Md.: 1950) 188:7 (2012), 3488–3495 http://doi.org/10.4049/jimmunol.1101977.
    • (2012) Journal of Immunology (Baltimore, Md.: 1950) , vol.188 , Issue.7 , pp. 3488-3495
    • Pichery, M.1    Mirey, E.2    Mercier, P.3    Lefrancais, E.4    Dujardin, A.5    Ortega, N.6
  • 164
    • 34748835898 scopus 로고    scopus 로고
    • IDO and regulatory T cells: A role for reverse signalling and non-canonical NF-kB activation
    • Puccetti, P., Grohmann, U., IDO and regulatory T cells: A role for reverse signalling and non-canonical NF-kB activation. Nature Reviews. Immunology 7:10 (2007), 817–823 http://doi.org/10.1038/nri2163.
    • (2007) Nature Reviews. Immunology , vol.7 , Issue.10 , pp. 817-823
    • Puccetti, P.1    Grohmann, U.2
  • 165
    • 79955529454 scopus 로고    scopus 로고
    • Trans-endocytosis of CD80 and CD86: A molecular basis for the cell-extrinsic function of CTLA-4
    • Qureshi, O.S., Zheng, Y., Nakamura, K., Attridge, K., Manzotti, C., Schmidt, E.M., et al. Trans-endocytosis of CD80 and CD86: A molecular basis for the cell-extrinsic function of CTLA-4. Science 332:6029 (2011), 600–603 http://doi.org/10.1126/science.1202947.
    • (2011) Science , vol.332 , Issue.6029 , pp. 600-603
    • Qureshi, O.S.1    Zheng, Y.2    Nakamura, K.3    Attridge, K.4    Manzotti, C.5    Schmidt, E.M.6
  • 166
    • 33749132564 scopus 로고    scopus 로고
    • Blockade of CTLA-4 on CD4+CD25 + regulatory T cells abrogates their function in vivo
    • Read, S., Greenwald, R., Izcue, A., Robinson, N., Mandelbrot, D., Francisco, L., et al. Blockade of CTLA-4 on CD4+CD25 + regulatory T cells abrogates their function in vivo. Journal of Immunology 177:7 (2006), 4376–4383 http://doi.org/10.4049/jimmunol.177.7.4376.
    • (2006) Journal of Immunology , vol.177 , Issue.7 , pp. 4376-4383
    • Read, S.1    Greenwald, R.2    Izcue, A.3    Robinson, N.4    Mandelbrot, D.5    Francisco, L.6
  • 167
    • 0034679567 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
    • Read, S., Malmstrom, V., Powrie, F., Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. Journal of Experimental Medicine 192:2 (2000), 295–302.
    • (2000) Journal of Experimental Medicine , vol.192 , Issue.2 , pp. 295-302
    • Read, S.1    Malmstrom, V.2    Powrie, F.3
  • 168
    • 36248995916 scopus 로고    scopus 로고
    • Involvement of cellular death in TRAIL|[sol]|DR5-dependent suppression induced by CD4|[plus]|CD25|[plus]| regulatory T cells
    • Ren, X., Ye, F., Jiang, Z., Chu, Y., Xiong, S., Wang, Y., Involvement of cellular death in TRAIL|[sol]|DR5-dependent suppression induced by CD4|[plus]|CD25|[plus]| regulatory T cells. Cell Death and Differentiation 14:12 (2007), 2076–2084 http://doi.org/10.1038/sj.cdd.4402220.
    • (2007) Cell Death and Differentiation , vol.14 , Issue.12 , pp. 2076-2084
    • Ren, X.1    Ye, F.2    Jiang, Z.3    Chu, Y.4    Xiong, S.5    Wang, Y.6
  • 171
    • 77954738601 scopus 로고    scopus 로고
    • Inducible Foxp3 + regulatory T-cell development by a commensal bacterium of the intestinal microbiota
    • Round, J.L., Mazmanian, S.K., Inducible Foxp3 + regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proceedings of the National Academy of Sciences of the United States of America 107:27 (2010), 12204–12209 http://doi.org/10.1073/pnas.0909122107.
    • (2010) Proceedings of the National Academy of Sciences of the United States of America , vol.107 , Issue.27 , pp. 12204-12209
    • Round, J.L.1    Mazmanian, S.K.2
  • 172
    • 41549159660 scopus 로고    scopus 로고
    • Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces
    • Rubtsov, Y.P., Rasmussen, J.P., Chi, E.Y., Fontenot, J., Castelli, L., Ye, X., et al. Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity 28:4 (2008), 546–558 http://doi.org/10.1016/j.immuni.2008.02.017.
    • (2008) Immunity , vol.28 , Issue.4 , pp. 546-558
    • Rubtsov, Y.P.1    Rasmussen, J.P.2    Chi, E.Y.3    Fontenot, J.4    Castelli, L.5    Ye, X.6
  • 174
    • 58249089749 scopus 로고    scopus 로고
    • Tumor-infiltrating FOXP3 + T regulatory cells show strong prognostic significance in colorectal cancer
    • Salama, P., Phillips, M., Grieu, F., Morris, M., Zeps, N., Joseph, D., et al. Tumor-infiltrating FOXP3 + T regulatory cells show strong prognostic significance in colorectal cancer. Journal of Clinical Oncology 27:2 (2009), 186–192 http://doi.org/10.1200/JCO.2008.18.7229.
    • (2009) Journal of Clinical Oncology , vol.27 , Issue.2 , pp. 186-192
    • Salama, P.1    Phillips, M.2    Grieu, F.3    Morris, M.4    Zeps, N.5    Joseph, D.6
  • 175
    • 0034083091 scopus 로고    scopus 로고
    • The role of chemokine receptors in primary, effector, and memory immune responses
    • Sallusto, F., Mackay, C.R., Lanzavecchia, A., The role of chemokine receptors in primary, effector, and memory immune responses. Annual Review of Immunology 18 (2000), 593–620 http://doi.org/10.1146/annurev.immunol.18.1.593.
    • (2000) Annual Review of Immunology , vol.18 , pp. 593-620
    • Sallusto, F.1    Mackay, C.R.2    Lanzavecchia, A.3
  • 176
    • 0035059417 scopus 로고    scopus 로고
    • Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation
    • Salomon, B., Bluestone, J.A., Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation. Annual Review of Immunology 19:1 (2001), 225–252 http://doi.org/10.1146/annurev.immunol.19.1.225.
    • (2001) Annual Review of Immunology , vol.19 , Issue.1 , pp. 225-252
    • Salomon, B.1    Bluestone, J.A.2
  • 177
    • 84940720421 scopus 로고    scopus 로고
    • Monitoring regulatory T cells in clinical samples: Consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry
    • Santegoets, S.J.A.M., Dijkgraaf, E.M., Battaglia, A., Beckhove, P., Britten, C.M., Gallimore, A., et al. Monitoring regulatory T cells in clinical samples: Consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry. Cancer Immunology, Immunotherapy 64:10 (2015), 1271–1286 http://doi.org/10.1007/s00262-015-1729-x.
    • (2015) Cancer Immunology, Immunotherapy , vol.64 , Issue.10 , pp. 1271-1286
    • Santegoets, S.J.A.M.1    Dijkgraaf, E.M.2    Battaglia, A.3    Beckhove, P.4    Britten, C.M.5    Gallimore, A.6
  • 178
    • 40249108222 scopus 로고    scopus 로고
    • Neuropilin-1 expression on regulatory T cells enhances their interactions with dendritic cells during antigen recognition
    • Sarris, M., Andersen, K.G., Randow, F., Mayr, L., Betz, A.G., Neuropilin-1 expression on regulatory T cells enhances their interactions with dendritic cells during antigen recognition. Immunity 28:3 (2008), 402–413 http://doi.org/10.1016/j.immuni.2008.01.012.
    • (2008) Immunity , vol.28 , Issue.3 , pp. 402-413
    • Sarris, M.1    Andersen, K.G.2    Randow, F.3    Mayr, L.4    Betz, A.G.5
  • 179
    • 34250336452 scopus 로고    scopus 로고
    • Altering the distribution of Foxp3 + regulatory T cells results in tissue-specific inflammatory disease
    • Sather, B.D., Treuting, P., Perdue, N., Miazgowicz, M., Fontenot, J.D., Rudensky, A.Y., et al. Altering the distribution of Foxp3 + regulatory T cells results in tissue-specific inflammatory disease. Journal of Experimental Medicine 204:6 (2007), 1335–1347 http://doi.org/10.1084/jem.20070081.
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.6 , pp. 1335-1347
    • Sather, B.D.1    Treuting, P.2    Perdue, N.3    Miazgowicz, M.4    Fontenot, J.D.5    Rudensky, A.Y.6
  • 180
    • 84947441940 scopus 로고    scopus 로고
    • A wave of regulatory T cells into neonatal skin mediates tolerance to commensal microbes
    • Scharschmidt, T.C., Vasquez, K.S., Truong, H.-A., Gearty, S.V., Pauli, M.L., Nosbaum, A., et al. A wave of regulatory T cells into neonatal skin mediates tolerance to commensal microbes. Immunity 43:5 (2015), 1011–1021 http://doi.org/10.1016/j.immuni.2015.10.016.
    • (2015) Immunity , vol.43 , Issue.5 , pp. 1011-1021
    • Scharschmidt, T.C.1    Vasquez, K.S.2    Truong, H.-A.3    Gearty, S.V.4    Pauli, M.L.5    Nosbaum, A.6
  • 181
    • 36249022697 scopus 로고    scopus 로고
    • Competition for cytokines: Treg cells take all
    • Scheffold, A., Murphy, K.M., Höfer, T., Competition for cytokines: Treg cells take all. Nature Immunology 8:12 (2007), 1285–1287 http://doi.org/10.1038/ni1207-1285.
    • (2007) Nature Immunology , vol.8 , Issue.12 , pp. 1285-1287
    • Scheffold, A.1    Murphy, K.M.2    Höfer, T.3
  • 182
    • 84918506186 scopus 로고    scopus 로고
    • Tissue-resident memory T cells
    • Schenkel, J.M., Masopust, D., Tissue-resident memory T cells. Immunity 41:6 (2014), 886–897 http://doi.org/10.1016/j.immuni.2014.12.007.
    • (2014) Immunity , vol.41 , Issue.6 , pp. 886-897
    • Schenkel, J.M.1    Masopust, D.2
  • 183
    • 84906571227 scopus 로고    scopus 로고
    • The alarmin IL-33 promotes regulatory T-cell function in the intestine
    • Schiering, C., Krausgruber, T., Chomka, A., Fröhlich, A., Adelmann, K., Wohlfert, E.A., et al. The alarmin IL-33 promotes regulatory T-cell function in the intestine. Nature 513:7519 (2014), 564–568 http://doi.org/10.1038/nature13577.
    • (2014) Nature , vol.513 , Issue.7519 , pp. 564-568
    • Schiering, C.1    Krausgruber, T.2    Chomka, A.3    Fröhlich, A.4    Adelmann, K.5    Wohlfert, E.A.6
  • 184
    • 84864005209 scopus 로고    scopus 로고
    • Phenotypic and functional characteristics of CD4 + CD39 + FOXP3 + and CD4 + CD39 + FOXP3neg T-cell subsets in cancer patients
    • Schuler, P.J., Schilling, B., Harasymczuk, M., Hoffmann, T.K., Johnson, J., Lang, S., et al. Phenotypic and functional characteristics of CD4 + CD39 + FOXP3 + and CD4 + CD39 + FOXP3neg T-cell subsets in cancer patients. European Journal of Immunology 42:7 (2012), 1876–1885 http://doi.org/10.1002/eji.201142347.
    • (2012) European Journal of Immunology , vol.42 , Issue.7 , pp. 1876-1885
    • Schuler, P.J.1    Schilling, B.2    Harasymczuk, M.3    Hoffmann, T.K.4    Johnson, J.5    Lang, S.6
  • 185
    • 33645510596 scopus 로고    scopus 로고
    • Persistence of naive CD45RA + regulatory T cells in adult life
    • Seddiki, N., Santner-Nanan, B., Tangye, S.G., Alexander, S.I., Solomon, M., Lee, S., et al. Persistence of naive CD45RA + regulatory T cells in adult life. Blood 107:7 (2006), 2830–2838 http://doi.org/10.1182/blood-2005-06-2403.
    • (2006) Blood , vol.107 , Issue.7 , pp. 2830-2838
    • Seddiki, N.1    Santner-Nanan, B.2    Tangye, S.G.3    Alexander, S.I.4    Solomon, M.5    Lee, S.6
  • 186
    • 0034141684 scopus 로고    scopus 로고
    • The third function of the thymus
    • Seddon, B., Mason, D., The third function of the thymus. Immunology Today 21:2 (2000), 95–99.
    • (2000) Immunology Today , vol.21 , Issue.2 , pp. 95-99
    • Seddon, B.1    Mason, D.2
  • 188
    • 84861462335 scopus 로고    scopus 로고
    • Human epidermal langerhans cells maintain immune homeostasis in skin by activating skin resident regulatory T cells
    • Seneschal, J., Clark, R.A., Gehad, A., Baecher-Allan, C.M., Kupper, T.S., Human epidermal langerhans cells maintain immune homeostasis in skin by activating skin resident regulatory T cells. Immunity 36:5 (2012), 873–884 http://doi.org/10.1016/j.immuni.2012.03.018.
    • (2012) Immunity , vol.36 , Issue.5 , pp. 873-884
    • Seneschal, J.1    Clark, R.A.2    Gehad, A.3    Baecher-Allan, C.M.4    Kupper, T.S.5
  • 191
    • 33645289121 scopus 로고    scopus 로고
    • CD69 acts downstream of interferon-|[alpha]|/|[beta]| to inhibit S1P1 and lymphocyte egress from lymphoid organs
    • Shiow, L.R., Rosen, D.B., Brdičková, N., et al. CD69 acts downstream of interferon-|[alpha]|/|[beta]| to inhibit S1P1 and lymphocyte egress from lymphoid organs. Nature 440:7083 (2006), 540–544 http://doi.org/10.1038/nature04606.
    • (2006) Nature , vol.440 , Issue.7083 , pp. 540-544
    • Shiow, L.R.1    Rosen, D.B.2    Brdičková, N.3
  • 192
    • 84923094757 scopus 로고    scopus 로고
    • Concomitant analysis of Helios and Neuropilin-1 as a marker to detect thymic derived regulatory T cells in naïve mice
    • Singh, K., Hjort, M., Thorvaldson, L., Sandler, S., Concomitant analysis of Helios and Neuropilin-1 as a marker to detect thymic derived regulatory T cells in naïve mice. Scientific Reports, 5, 2015, 7767 http://doi.org/10.1038/srep07767.
    • (2015) Scientific Reports , vol.5 , pp. 7767
    • Singh, K.1    Hjort, M.2    Thorvaldson, L.3    Sandler, S.4
  • 193
    • 84888013845 scopus 로고    scopus 로고
    • Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8 + T cells
    • Skon, C.N., Lee, J.-Y., Anderson, K.G., Masopust, D., Hogquist, K.A., Jameson, S.C., Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8 + T cells. Nature Immunology 14:12 (2013), 1285–1293 http://doi.org/10.1038/ni.2745.
    • (2013) Nature Immunology , vol.14 , Issue.12 , pp. 1285-1293
    • Skon, C.N.1    Lee, J.-Y.2    Anderson, K.G.3    Masopust, D.4    Hogquist, K.A.5    Jameson, S.C.6
  • 194
    • 84878659255 scopus 로고    scopus 로고
    • Lung-resident tissue macrophages generate Foxp3 + regulatory T cells and promote airway tolerance
    • Soroosh, P., Doherty, T.A., Duan, W., Mehta, A.K., Choi, H., Adams, Y.F., et al. Lung-resident tissue macrophages generate Foxp3 + regulatory T cells and promote airway tolerance. The Journal of Experimental Medicine 210:4 (2013), 775–788 http://doi.org/10.1084/jem.20121849.
    • (2013) The Journal of Experimental Medicine , vol.210 , Issue.4 , pp. 775-788
    • Soroosh, P.1    Doherty, T.A.2    Duan, W.3    Mehta, A.K.4    Choi, H.5    Adams, Y.F.6
  • 195
    • 2942733256 scopus 로고    scopus 로고
    • Human CD25 + regulatory T cells: Two subsets defined by the integrins alpha 4 beta 7 or alpha 4 beta 1 confer distinct suppressive properties upon CD4 + T helper cells
    • Stassen, M., Fondel, S., Bopp, T., Richter, C., Müller, C., Kubach, J., et al. Human CD25 + regulatory T cells: Two subsets defined by the integrins alpha 4 beta 7 or alpha 4 beta 1 confer distinct suppressive properties upon CD4 + T helper cells. European Journal of Immunology 34:5 (2004), 1303–1311 http://doi.org/10.1002/eji.200324656.
    • (2004) European Journal of Immunology , vol.34 , Issue.5 , pp. 1303-1311
    • Stassen, M.1    Fondel, S.2    Bopp, T.3    Richter, C.4    Müller, C.5    Kubach, J.6
  • 196
    • 0034492970 scopus 로고    scopus 로고
    • Perspectives on the role of the human gut microbiota and its modulation by pro- and prebiotics
    • Steer, T., Carpenter, H., Tuohy, K., Gibson, G.R., Perspectives on the role of the human gut microbiota and its modulation by pro- and prebiotics. Nutrition Research Reviews 13:02 (2000), 229–254 http://doi.org/10.1079/095442200108729089.
    • (2000) Nutrition Research Reviews , vol.13 , Issue.2 , pp. 229-254
    • Steer, T.1    Carpenter, H.2    Tuohy, K.3    Gibson, G.R.4
  • 198
    • 33645077332 scopus 로고    scopus 로고
    • Infected site-restricted Foxp3 + natural regulatory T cells are specific for microbial antigens
    • Suffia, I.J., Reckling, S.K., Piccirillo, C.A., Goldszmid, R.S., Belkaid, Y., Infected site-restricted Foxp3 + natural regulatory T cells are specific for microbial antigens. Journal of Experimental Medicine 203:3 (2006), 777–788 http://doi.org/10.1084/jem.20052056.
    • (2006) Journal of Experimental Medicine , vol.203 , Issue.3 , pp. 777-788
    • Suffia, I.J.1    Reckling, S.K.2    Piccirillo, C.A.3    Goldszmid, R.S.4    Belkaid, Y.5
  • 199
    • 0034677646 scopus 로고    scopus 로고
    • A novel transcription factor, T-bet, directs Th1 lineage commitment
    • Szabo, S.J., Kim, S.T., Costa, G.L., Zhang, X., Fathman, C.G., Glimcher, L.H., A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100:6 (2000), 655–669.
    • (2000) Cell , vol.100 , Issue.6 , pp. 655-669
    • Szabo, S.J.1    Kim, S.T.2    Costa, G.L.3    Zhang, X.4    Fathman, C.G.5    Glimcher, L.H.6
  • 200
  • 201
    • 0019442054 scopus 로고
    • Experimental autoimmune orchitis after neonatal thymectomy in the mouse
    • Taguchi, O., Nishizuka, Y., Experimental autoimmune orchitis after neonatal thymectomy in the mouse. Clinical and Experimental Immunology 46:2 (1981), 425–434.
    • (1981) Clinical and Experimental Immunology , vol.46 , Issue.2 , pp. 425-434
    • Taguchi, O.1    Nishizuka, Y.2
  • 202
    • 0031647622 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25+CD4 + naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
    • Takahashi, T., Kuniyasu, Y., Toda, M., Sakaguchi, N., Itoh, M., Iwata, M., et al. Immunologic self-tolerance maintained by CD25+CD4 + naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state. International Immunology 10:12 (1998), 1969–1980.
    • (1998) International Immunology , vol.10 , Issue.12 , pp. 1969-1980
    • Takahashi, T.1    Kuniyasu, Y.2    Toda, M.3    Sakaguchi, N.4    Itoh, M.5    Iwata, M.6
  • 203
    • 0034679560 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
    • Takahashi, T., Tagami, T., Yamazaki, S., Uede, T., Shimizu, J., Sakaguchi, N., et al. Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. The Journal of Experimental Medicine 192:2 (2000), 303–310.
    • (2000) The Journal of Experimental Medicine , vol.192 , Issue.2 , pp. 303-310
    • Takahashi, T.1    Tagami, T.2    Yamazaki, S.3    Uede, T.4    Shimizu, J.5    Sakaguchi, N.6
  • 204
    • 29244482759 scopus 로고    scopus 로고
    • Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
    • Tang, Q., Adams, J.Y., Tooley, A.J., Bi, M., Fife, B.T., Serra, P., et al. Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nature Immunology 7:1 (2006), 83–92.
    • (2006) Nature Immunology , vol.7 , Issue.1 , pp. 83-92
    • Tang, Q.1    Adams, J.Y.2    Tooley, A.J.3    Bi, M.4    Fife, B.T.5    Serra, P.6
  • 205
    • 39449126502 scopus 로고    scopus 로고
    • The Foxp3 + regulatory T cell: A jack of all trades, master of regulation
    • Tang, Q., Bluestone, J.A., The Foxp3 + regulatory T cell: A jack of all trades, master of regulation. Nature Reviews. Immunology 9:3 (2008), 239–244.
    • (2008) Nature Reviews. Immunology , vol.9 , Issue.3 , pp. 239-244
    • Tang, Q.1    Bluestone, J.A.2
  • 206
    • 84964403670 scopus 로고    scopus 로고
    • Development and maintenance of intestinal regulatory T cells
    • Tanoue, T., Atarashi, K., Honda, K., Development and maintenance of intestinal regulatory T cells. Nature Reviews. Immunology 16:5 (2016), 295–309 http://doi.org/10.1038/nri.2016.36.
    • (2016) Nature Reviews. Immunology , vol.16 , Issue.5 , pp. 295-309
    • Tanoue, T.1    Atarashi, K.2    Honda, K.3
  • 207
    • 84929944502 scopus 로고    scopus 로고
    • Peripheral regulatory T lymphocytes recirculating to the thymus suppress the development of their precursors
    • Thiault, N., Darrigues, J., Adoue, V., Gros, M., Binet, B., Perals, C., et al. Peripheral regulatory T lymphocytes recirculating to the thymus suppress the development of their precursors. Nature Immunology 16:6 (2015), 628–634 http://doi.org/10.1038/ni.3150.
    • (2015) Nature Immunology , vol.16 , Issue.6 , pp. 628-634
    • Thiault, N.1    Darrigues, J.2    Adoue, V.3    Gros, M.4    Binet, B.5    Perals, C.6
  • 208
    • 84937636760 scopus 로고    scopus 로고
    • Emerging concepts in tissue-resident T cells: Lessons from humans
    • Thome, J.J.C., Farber, D.L., Emerging concepts in tissue-resident T cells: Lessons from humans. Trends in Immunology 36:7 (2015), 428–435 http://doi.org/10.1016/j.it.2015.05.003.
    • (2015) Trends in Immunology , vol.36 , Issue.7 , pp. 428-435
    • Thome, J.J.C.1    Farber, D.L.2
  • 209
    • 0031821875 scopus 로고    scopus 로고
    • CD4+CD25 + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • Thornton, A.M., Shevach, E.M., CD4+CD25 + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. Journal of Experimental Medicine 188:2 (1998), 287–296.
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.2 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 210
    • 65549168545 scopus 로고    scopus 로고
    • Selective expression of latency-associated peptide (LAP) and IL-1 receptor type I/II (CD121a/CD121b) on activated human FOXP3 + regulatory T cells allows for their purification from expansion cultures
    • Tran, D.Q., Andersson, J., Hardwick, D., Bebris, L., Illei, G.G., Shevach, E.M., Selective expression of latency-associated peptide (LAP) and IL-1 receptor type I/II (CD121a/CD121b) on activated human FOXP3 + regulatory T cells allows for their purification from expansion cultures. Blood 113:21 (2009), 5125–5133 http://doi.org/10.1182/blood-2009-01-199950.
    • (2009) Blood , vol.113 , Issue.21 , pp. 5125-5133
    • Tran, D.Q.1    Andersson, J.2    Hardwick, D.3    Bebris, L.4    Illei, G.G.5    Shevach, E.M.6
  • 211
    • 84923490401 scopus 로고    scopus 로고
    • Protein kinase CK2 enables regulatory T cells to suppress excessive TH2 responses in vivo
    • Ulges, A., Klein, M., Reuter, S., Gerlitzki, B., Hoffmann, M., Grebe, N., et al. Protein kinase CK2 enables regulatory T cells to suppress excessive TH2 responses in vivo. Nature Immunology 16:3 (2015), 267–275 http://doi.org/10.1038/ni.3083.
    • (2015) Nature Immunology , vol.16 , Issue.3 , pp. 267-275
    • Ulges, A.1    Klein, M.2    Reuter, S.3    Gerlitzki, B.4    Hoffmann, M.5    Grebe, N.6
  • 213
    • 84912113033 scopus 로고    scopus 로고
    • Continuous T cell receptor signals maintain a functional regulatory T cell pool
    • Vahl, J.C., Drees, C., Heger, K., Heink, S., Fischer, J.C., Nedjic, J., et al. Continuous T cell receptor signals maintain a functional regulatory T cell pool. Immunity 41:5 (2014), 722–736 http://doi.org/10.1016/j.immuni.2014.10.012.
    • (2014) Immunity , vol.41 , Issue.5 , pp. 722-736
    • Vahl, J.C.1    Drees, C.2    Heger, K.3    Heink, S.4    Fischer, J.C.5    Nedjic, J.6
  • 215
    • 84923607143 scopus 로고    scopus 로고
    • The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells
    • Vasanthakumar, A., Moro, K., Xin, A., Liao, Y., Gloury, R., Kawamoto, S., et al. The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells. Nature Immunology 16 (2015), 276–285 http://doi.org/10.1038/ni.3085.
    • (2015) Nature Immunology , vol.16 , pp. 276-285
    • Vasanthakumar, A.1    Moro, K.2    Xin, A.3    Liao, Y.4    Gloury, R.5    Kawamoto, S.6
  • 217
  • 218
    • 0025231503 scopus 로고
    • Developmental biology of T cells in T cell-receptor transgenic mice
    • von Boehmer, H., Developmental biology of T cells in T cell-receptor transgenic mice. Annual Review of Immunology 8:1 (1990), 531–556 http://doi.org/10.1146/annurev.iy.08.040190.002531.
    • (1990) Annual Review of Immunology , vol.8 , Issue.1 , pp. 531-556
    • von Boehmer, H.1
  • 219
    • 55849107041 scopus 로고    scopus 로고
    • The kinetics of CD4+Foxp3 + T cell accumulation during a human cutaneous antigen-specific memory response in vivo
    • Vukmanovic-Stejic, M., Agius, E., Booth, N., Dunne, P.J., Lacy, K.E., Reed, J.R., et al. The kinetics of CD4+Foxp3 + T cell accumulation during a human cutaneous antigen-specific memory response in vivo. The Journal of Clinical Investigation 118:11 (2008), 3639–3650 http://doi.org/10.1172/JCI35834.
    • (2008) The Journal of Clinical Investigation , vol.118 , Issue.11 , pp. 3639-3650
    • Vukmanovic-Stejic, M.1    Agius, E.2    Booth, N.3    Dunne, P.J.4    Lacy, K.E.5    Reed, J.R.6
  • 220
    • 70349466655 scopus 로고    scopus 로고
    • Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate
    • Wang, L., Liu, R., Li, W., Chen, C., Katoh, H., Chen, G.-Y., et al. Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate. Cancer Cell 16:4 (2009), 336–346 http://doi.org/10.1016/j.ccr.2009.08.016.
    • (2009) Cancer Cell , vol.16 , Issue.4 , pp. 336-346
    • Wang, L.1    Liu, R.2    Li, W.3    Chen, C.4    Katoh, H.5    Chen, G.-Y.6
  • 221
    • 84867899425 scopus 로고    scopus 로고
    • Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3 + T reg cells
    • S1
    • Weiss, J.M., Bilate, A.M., Gobert, M., Ding, Y., Curotto de Lafaille, M.A., Parkhurst, C.N., et al. Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3 + T reg cells. The Journal of Experimental Medicine 209:10 (2012), 1723–1742 S1 http://doi.org/10.1084/jem.20120914.
    • (2012) The Journal of Experimental Medicine , vol.209 , Issue.10 , pp. 1723-1742
    • Weiss, J.M.1    Bilate, A.M.2    Gobert, M.3    Ding, Y.4    Curotto de Lafaille, M.A.5    Parkhurst, C.N.6
  • 222
    • 84929950085 scopus 로고    scopus 로고
    • Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competition
    • Weist, B.M., Kurd, N., Boussier, J., Chan, S.W., Robey, E.A., Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competition. Nature Immunology 16:6 (2015), 635–641 http://doi.org/10.1038/ni.3171.
    • (2015) Nature Immunology , vol.16 , Issue.6 , pp. 635-641
    • Weist, B.M.1    Kurd, N.2    Boussier, J.3    Chan, S.W.4    Robey, E.A.5
  • 223
    • 84907055119 scopus 로고    scopus 로고
    • Induced regulatory T cells in inhibitory microenvironments created by cancer
    • Whiteside, T.L., Induced regulatory T cells in inhibitory microenvironments created by cancer. Expert Opinion on Biological Therapy 14:10 (2014), 1411–1425 http://doi.org/10.1517/14712598.2014.927432.
    • (2014) Expert Opinion on Biological Therapy , vol.14 , Issue.10 , pp. 1411-1425
    • Whiteside, T.L.1
  • 224
    • 58349116249 scopus 로고    scopus 로고
    • Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue
    • Wieczorek, G., Asemissen, A., Model, F., Turbachova, I., Floess, S., Liebenberg, V., et al. Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue. Cancer Research 69:2 (2009), 599–608 http://doi.org/10.1158/0008-5472.CAN-08-2361.
    • (2009) Cancer Research , vol.69 , Issue.2 , pp. 599-608
    • Wieczorek, G.1    Asemissen, A.2    Model, F.3    Turbachova, I.4    Floess, S.5    Liebenberg, V.6
  • 226
    • 53749094183 scopus 로고    scopus 로고
    • CTLA-4 control over Foxp3 + regulatory T cell function
    • Wing, K., Onishi, Y., Prieto-Martin, P., Yamaguchi, T., Miyara, M., Fehervari, Z., et al. CTLA-4 control over Foxp3 + regulatory T cell function. Science 322:5899 (2008), 271–275 http://doi.org/10.1126/science.1160062.
    • (2008) Science , vol.322 , Issue.5899 , pp. 271-275
    • Wing, K.1    Onishi, Y.2    Prieto-Martin, P.3    Yamaguchi, T.4    Miyara, M.5    Fehervari, Z.6
  • 228
    • 28544433483 scopus 로고    scopus 로고
    • The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer
    • Wolf, D., Wolf, A.M., Rumpold, H., Fiegl, H., Zeimet, A.G., Muller-Holzner, E., et al. The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer. Clinical Cancer Research 11:23 (2005), 8326–8331.
    • (2005) Clinical Cancer Research , vol.11 , Issue.23 , pp. 8326-8331
    • Wolf, D.1    Wolf, A.M.2    Rumpold, H.3    Fiegl, H.4    Zeimet, A.G.5    Muller-Holzner, E.6
  • 229
    • 0035874949 scopus 로고    scopus 로고
    • Regulatory CD4+CD25 + T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer
    • Woo, E.Y., Chu, C.S., Goletz, T.J., Schlienger, K., Yeh, H., Coukos, G., et al. Regulatory CD4+CD25 + T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer. Cancer Research 61:12 (2001), 4766–4772 http://doi.org/10.1016/0167-5699(96)10027-X.
    • (2001) Cancer Research , vol.61 , Issue.12 , pp. 4766-4772
    • Woo, E.Y.1    Chu, C.S.2    Goletz, T.J.3    Schlienger, K.4    Yeh, H.5    Coukos, G.6
  • 230
    • 84863115998 scopus 로고    scopus 로고
    • Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T cell function to promote tumoral immune escape
    • Woo, S.-R., Turnis, M.E., Goldberg, M.V., Bankoti, J., Selby, M., Nirschl, C.J., et al. Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T cell function to promote tumoral immune escape. Cancer Research 72:4 (2012), 917–927 http://doi.org/10.1158/0008-5472.CAN-11-1620.
    • (2012) Cancer Research , vol.72 , Issue.4 , pp. 917-927
    • Woo, S.-R.1    Turnis, M.E.2    Goldberg, M.V.3    Bankoti, J.4    Selby, M.5    Nirschl, C.J.6
  • 232
    • 84874635440 scopus 로고    scopus 로고
    • Tim-3 expression defines regulatory T cells in human tumors
    • Yan, J., Zhang, Y., Zhang, J.-P., Liang, J., Li, L., Zheng, L., Tim-3 expression defines regulatory T cells in human tumors. PLoS One, 8(3), 2013, e58006 http://doi.org/10.1371/journal.pone.0058006.
    • (2013) PLoS One , vol.8 , Issue.3 , pp. e58006
    • Yan, J.1    Zhang, Y.2    Zhang, J.-P.3    Liang, J.4    Li, L.5    Zheng, L.6
  • 233
    • 84961833659 scopus 로고    scopus 로고
    • Foxp3 + T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation
    • Yang, B.-H., Hagemann, S., Mamareli, P., Lauer, U., Hoffmann, U., Beckstette, M., et al. Foxp3 + T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation. Mucosal Immunology 9:2 (2015), 444–457 http://doi.org/10.1038/mi.2015.74.
    • (2015) Mucosal Immunology , vol.9 , Issue.2 , pp. 444-457
    • Yang, B.-H.1    Hagemann, S.2    Mamareli, P.3    Lauer, U.4    Hoffmann, U.5    Beckstette, M.6
  • 234
    • 57849101994 scopus 로고    scopus 로고
    • The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells
    • Yu, X., Harden, K., Gonzalez, L.C., Francesco, M., Chiang, E., Irving, B., et al. The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells. Nature Immunology 10:1 (2009), 48–57 http://doi.org/10.1038/ni.1674.
    • (2009) Nature Immunology , vol.10 , Issue.1 , pp. 48-57
    • Yu, X.1    Harden, K.2    Gonzalez, L.C.3    Francesco, M.4    Chiang, E.5    Irving, B.6
  • 235
    • 38049141544 scopus 로고    scopus 로고
    • A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells
    • Zarek, P.E., Huang, C.-T., Lutz, E.R., Kowalski, J., Horton, M.R., Linden, J., et al. A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells. Blood 111:1 (2008), 251–259 http://doi.org/10.1182/blood-2007-03-081646.
    • (2008) Blood , vol.111 , Issue.1 , pp. 251-259
    • Zarek, P.E.1    Huang, C.-T.2    Lutz, E.R.3    Kowalski, J.4    Horton, M.R.5    Linden, J.6
  • 236
    • 84877582160 scopus 로고    scopus 로고
    • Severe obesity increases adipose tissue expression of interleukin-33 and its receptor ST2, both predominantly detectable in endothelial cells of human adipose tissue
    • Zeyda, M., Wernly, B., Demyanets, S., Kaun, C., Hämmerle, M., Hantusch, B., et al. Severe obesity increases adipose tissue expression of interleukin-33 and its receptor ST2, both predominantly detectable in endothelial cells of human adipose tissue. International Journal of Obesity (2005) 37:5 (2013), 658–665 http://doi.org/10.1038/ijo.2012.118.
    • (2013) International Journal of Obesity (2005) , vol.37 , Issue.5 , pp. 658-665
    • Zeyda, M.1    Wernly, B.2    Demyanets, S.3    Kaun, C.4    Hämmerle, M.5    Hantusch, B.6
  • 237
    • 33646567156 scopus 로고    scopus 로고
    • Activated CD4+CD25 + T cells selectively kill B lymphocytes
    • Zhao, D.M., Thornton, A.M., Dipaolo, R.J., Shevach, E.M., Activated CD4+CD25 + T cells selectively kill B lymphocytes. Blood 107 (2006), 3925–3932.
    • (2006) Blood , vol.107 , pp. 3925-3932
    • Zhao, D.M.1    Thornton, A.M.2    Dipaolo, R.J.3    Shevach, E.M.4
  • 238
    • 62649165369 scopus 로고    scopus 로고
    • Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses
    • Zheng, Y., Chaudhry, A., Kas, A., deRoos, P., Kim, J.M., Chu, T.-T., et al. Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses. Nature 458:7236 (2009), 351–356 http://doi.org/10.1038/nature07674.
    • (2009) Nature , vol.458 , Issue.7236 , pp. 351-356
    • Zheng, Y.1    Chaudhry, A.2    Kas, A.3    deRoos, P.4    Kim, J.M.5    Chu, T.-T.6
  • 239
    • 77952313777 scopus 로고    scopus 로고
    • Differentiation of effector CD4 T cell populations (*)
    • Zhu, J., Yamane, H., Paul, W.E., Differentiation of effector CD4 T cell populations (*). Annual Review of Immunology 28:1 (2010), 445–489 http://doi.org/10.1146/annurev-immunol-030409-101212.
    • (2010) Annual Review of Immunology , vol.28 , Issue.1 , pp. 445-489
    • Zhu, J.1    Yamane, H.2    Paul, W.E.3
  • 240
    • 33646168597 scopus 로고    scopus 로고
    • FOXP3: Of mice and men
    • Ziegler, S.F., FOXP3: Of mice and men. Annual Review of Immunology 24:1 (2006), 209–226 http://doi.org/10.1146/annurev.immunol.24.021605.090547.
    • (2006) Annual Review of Immunology , vol.24 , Issue.1 , pp. 209-226
    • Ziegler, S.F.1
  • 241
    • 34250863911 scopus 로고    scopus 로고
    • FOXP3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene
    • Zuo, T., Wang, L., Morrison, C., Chang, X., Zhang, H., Li, W., et al. FOXP3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene. Cell 129:7 (2007), 1275–1286 http://doi.org/10.1016/j.cell.2007.04.034.
    • (2007) Cell , vol.129 , Issue.7 , pp. 1275-1286
    • Zuo, T.1    Wang, L.2    Morrison, C.3    Chang, X.4    Zhang, H.5    Li, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.