The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

Nature Immunology

Volumn 10, Issue 1, 2009, Pages 48-57

  Yu, Xin ^a   Harden, Kristin ^a   Gonzalez, Lino C ^a   Francesco, Michelle ^a   Chiang, Eugene ^a   Irving, Bryan ^a   Tom, Irene ^a   Ivelja, Sinisa ^a   Refino, Canio J ^a   Clark, Hilary ^a   Eaton, Dan ^a   Grogan, Jane L ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANE PROTEIN; CYTOKINE; FC RECEPTOR; HYBRID PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12P40; PROTEIN TIGIT; SMALL INTERFERING RNA; TYROSINE; UNCLASSIFIED DRUG; VIRUS RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOREGULATION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLIOMYELITIS VIRUS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

AMINO ACID SEQUENCE; ANIMALS; CELL COMMUNICATION; CELL DIFFERENTIATION; CELLS, CULTURED; CHO CELLS; CRICETINAE; CRICETULUS; DENDRITIC CELLS; DOWN-REGULATION; HUMANS; IMMUNE TOLERANCE; IMMUNOLOGIC MEMORY; INTERLEUKIN-10; INTERLEUKIN-12 SUBUNIT P40; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC; RECEPTORS, VIRUS; SEQUENCE ALIGNMENT; T-LYMPHOCYTES;

EID: 57849101994     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1674     Document Type: Article

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