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Volumn 40, Issue 12, 2010, Pages 3325-3335

Efficient Treg depletion induces T-cell infiltration and rejection of large tumors

Author keywords

Immunotherapy; Treg; Tumor immunology

Indexed keywords

CD4 ANTIBODY; CD8A ANTIBODY; DIPHTHERIA TOXIN; INTERLEUKIN 2 RECEPTOR ALPHA; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY PC 61; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

EID: 78649557780     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201041093     Document Type: Article
Times cited : (104)

References (47)
  • 1
    • 0029925375 scopus 로고    scopus 로고
    • Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma
    • Clemente, C. G., Mihm, M. C. Jr., Bufalino, R., Zurrida, S., Collini, P. and Cascinelli, N., Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma. Cancer 1996. 77: 1303-1310.
    • (1996) Cancer , vol.77 , pp. 1303-1310
    • Clemente, C.G.1    Mihm Jr, M.C.2    Bufalino, R.3    Zurrida, S.4    Collini, P.5    Cascinelli, N.6
  • 2
    • 33947540564 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes predict sentinel lymph node positivity in patients with cutaneous melanoma
    • Taylor, R. C., Patel, A., Panageas, K. S., Busam, K. J. and Brady, M. S., Tumor-infiltrating lymphocytes predict sentinel lymph node positivity in patients with cutaneous melanoma. J. Clin. Oncol. 2007. 25: 869-875.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 869-875
    • Taylor, R.C.1    Patel, A.2    Panageas, K.S.3    Busam, K.J.4    Brady, M.S.5
  • 4
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • Galon, J., Costes, A., Sanchez-Cabo, F., Kirilovsky, A., Mlecnik, B., Lagorce-Pages, C., Tosolini, M. et al., Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 2006. 313: 1960-1964.
    • (2006) Science , vol.313 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3    Kirilovsky, A.4    Mlecnik, B.5    Lagorce-Pages, C.6    Tosolini, M.7
  • 5
    • 33846444354 scopus 로고    scopus 로고
    • High number of intraepithelial CD8+ tumor-infiltrating lymphocytes is associated with the absence of lymph node metastases in patients with large early-stage cervical cancer
    • Piersma, S. J., Jordanova, E. S., van Poelgeest, M. I., Kwappenberg, K. M., van der Hulst, J. M., Drijfhout, J. W., Melief, C. J. et al., High number of intraepithelial CD8+ tumor-infiltrating lymphocytes is associated with the absence of lymph node metastases in patients with large early-stage cervical cancer. Cancer Res. 2007. 67: 354-361.
    • (2007) Cancer Res. , vol.67 , pp. 354-361
    • Piersma, S.J.1    Jordanova, E.S.2    van Poelgeest, M.I.3    Kwappenberg, K.M.4    van der Hulst, J.M.5    Drijfhout, J.W.6    Melief, C.J.7
  • 6
    • 34447277894 scopus 로고    scopus 로고
    • Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection
    • Gao, Q., Qiu, S. J., Fan, J., Zhou, J., Wang, X. Y., Xiao, Y. S., Xu, Y. et al., Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection. J. Clin. Oncol. 2007. 25: 2586-2593.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 2586-2593
    • Gao, Q.1    Qiu, S.J.2    Fan, J.3    Zhou, J.4    Wang, X.Y.5    Xiao, Y.S.6    Xu, Y.7
  • 7
    • 55949118778 scopus 로고    scopus 로고
    • Prognostic implications of type and density of tumour-infiltrating lymphocytes in gastric cancer
    • Lee, H. E., Chae, S. W., Lee, Y. J., Kim, M. A., Lee, H. S., Lee, B. L. and Kim, W. H., Prognostic implications of type and density of tumour-infiltrating lymphocytes in gastric cancer. Br. J. Cancer. 2008. 99: 1704-1711.
    • (2008) Br. J. Cancer. , vol.99 , pp. 1704-1711
    • Lee, H.E.1    Chae, S.W.2    Lee, Y.J.3    Kim, M.A.4    Lee, H.S.5    Lee, B.L.6    Kim, W.H.7
  • 8
    • 34247271873 scopus 로고    scopus 로고
    • CD8 tumor-infiltrating lymphocytes are predictive of survival in muscle-invasive urothelial carcinoma
    • Sharma, P., Shen, Y., Wen, S., Yamada, S., Jungbluth, A. A., Gnjatic, S., Bajorin, D. F. et al., CD8 tumor-infiltrating lymphocytes are predictive of survival in muscle-invasive urothelial carcinoma. Proc. Natl. Acad. Sci. USA 2007. 104: 3967-3972.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 3967-3972
    • Sharma, P.1    Shen, Y.2    Wen, S.3    Yamada, S.4    Jungbluth, A.A.5    Gnjatic, S.6    Bajorin, D.F.7
  • 9
    • 38049000452 scopus 로고    scopus 로고
    • Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy
    • Buckanovich, R. J., Facciabene, A., Kim, S., Benencia, F., Sasaroli, D., Balint, K., Katsaros, D. et al., Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy. Nat. Med. 2008. 14: 28-36.
    • (2008) Nat. Med. , vol.14 , pp. 28-36
    • Buckanovich, R.J.1    Facciabene, A.2    Kim, S.3    Benencia, F.4    Sasaroli, D.5    Balint, K.6    Katsaros, D.7
  • 10
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy
    • Jain, R. K., Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 2005. 307: 58-62.
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 11
    • 49749149560 scopus 로고    scopus 로고
    • Modulation of the "blood-tumor" barrier improves immunotherapy
    • Manzur, M., Hamzah, J. and Ganss, R., Modulation of the "blood-tumor" barrier improves immunotherapy. Cell Cycle 2008. 7: 2452-2455.
    • (2008) Cell Cycle , vol.7 , pp. 2452-2455
    • Manzur, M.1    Hamzah, J.2    Ganss, R.3
  • 12
    • 43749112760 scopus 로고    scopus 로고
    • Vascular normalization in Rgs5-deficient tumours promotes immune destruction
    • Hamzah, J., Jugold, M., Kiessling, F., Rigby, P., Manzur, M., Marti, H. H., Rabie, T. et al., Vascular normalization in Rgs5-deficient tumours promotes immune destruction. Nature 2008. 453: 410-414.
    • (2008) Nature , vol.453 , pp. 410-414
    • Hamzah, J.1    Jugold, M.2    Kiessling, F.3    Rigby, P.4    Manzur, M.5    Marti, H.H.6    Rabie, T.7
  • 13
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
    • Sakaguchi, S., Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat. Immunol. 2005. 6: 345-352.
    • (2005) Nat. Immunol. , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 14
    • 34548132058 scopus 로고    scopus 로고
    • Functional and genomic analyses of FOXP3-transduced Jurkat-T cells as regulatory T (Treg)-like cells
    • Kim, J. Y., Kim, H. J., Hurt, E. M., Chen, X., Howard, O. M. and Farrar, W. L., Functional and genomic analyses of FOXP3-transduced Jurkat-T cells as regulatory T (Treg)-like cells. Biochem. Biophys. Res. Commun. 2007. 362: 44-50.
    • (2007) Biochem. Biophys. Res. Commun. , vol.362 , pp. 44-50
    • Kim, J.Y.1    Kim, H.J.2    Hurt, E.M.3    Chen, X.4    Howard, O.M.5    Farrar, W.L.6
  • 15
    • 33845948381 scopus 로고    scopus 로고
    • IL-6 produced by dendritic cells from lupus-prone mice inhibits CD4+CD25+ T cell regulatory functions
    • Wan, S., Xia, C. and Morel, L., IL-6 produced by dendritic cells from lupus-prone mice inhibits CD4+CD25+ T cell regulatory functions. J. Immunol. 2007. 178: 271-279.
    • (2007) J. Immunol. , vol.178 , pp. 271-279
    • Wan, S.1    Xia, C.2    Morel, L.3
  • 16
    • 0035874949 scopus 로고    scopus 로고
    • Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer
    • Woo, E. Y., Chu, C. S., Goletz, T. J., Schlienger, K., Yeh, H., Coukos, G., Rubin, S. C. et al., Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer. Cancer Res. 2001. 61: 4766-4772.
    • (2001) Cancer Res. , vol.61 , pp. 4766-4772
    • Woo, E.Y.1    Chu, C.S.2    Goletz, T.J.3    Schlienger, K.4    Yeh, H.5    Coukos, G.6    Rubin, S.C.7
  • 17
    • 0036721629 scopus 로고    scopus 로고
    • Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
    • Liyanage, U. K., Moore, T. T., Joo, H. G., Tanaka, Y., Herrmann, V., Doherty, G., Drebin, J. A. et al., Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J. Immunol. 2002. 169: 2756-2761.
    • (2002) J. Immunol. , vol.169 , pp. 2756-2761
    • Liyanage, U.K.1    Moore, T.T.2    Joo, H.G.3    Tanaka, Y.4    Herrmann, V.5    Doherty, G.6    Drebin, J.A.7
  • 18
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel, T. J., Coukos, G., Zou, L., Alvarez, X., Cheng, P., Mottram, P., Evdemon-Hogan, M. et al., Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med. 2004. 10: 942-949.
    • (2004) Nat. Med. , vol.10 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3    Alvarez, X.4    Cheng, P.5    Mottram, P.6    Evdemon-Hogan, M.7
  • 19
    • 33749317518 scopus 로고    scopus 로고
    • Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions
    • Hiraoka, N., Onozato, K., Kosuge, T. and Hirohashi, S., Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions. Clin. Cancer Res. 2006. 12: 5423-5434.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 5423-5434
    • Hiraoka, N.1    Onozato, K.2    Kosuge, T.3    Hirohashi, S.4
  • 20
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells, tumour immunity and immunotherapy
    • Zou, W., Regulatory T cells, tumour immunity and immunotherapy. Nat. Rev. Immunol. 2006. 6: 295-307.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 295-307
    • Zou, W.1
  • 21
    • 33646239606 scopus 로고    scopus 로고
    • Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent
    • Valzasina, B., Piconese, S., Guiducci, C. and Colombo, M. P., Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent. Cancer Res. 2006. 66: 4488-4495.
    • (2006) Cancer Res. , vol.66 , pp. 4488-4495
    • Valzasina, B.1    Piconese, S.2    Guiducci, C.3    Colombo, M.P.4
  • 22
    • 33846913897 scopus 로고    scopus 로고
    • Natural regulatory T cells and de novo-induced regulatory T cells contribute independently to tumor-specific tolerance
    • Zhou, G. and Levitsky, H. I., Natural regulatory T cells and de novo-induced regulatory T cells contribute independently to tumor-specific tolerance. J. Immunol. 2007. 178: 2155-2162.
    • (2007) J. Immunol. , vol.178 , pp. 2155-2162
    • Zhou, G.1    Levitsky, H.I.2
  • 23
    • 33847337912 scopus 로고    scopus 로고
    • Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta
    • Liu, V. C., Wong, L. Y., Jang, T., Shah, A. H., Park, I., Yang, X., Zhang, Q. et al., Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta. J. Immunol. 2007. 178: 2883-2892.
    • (2007) J. Immunol. , vol.178 , pp. 2883-2892
    • Liu, V.C.1    Wong, L.Y.2    Jang, T.3    Shah, A.H.4    Park, I.5    Yang, X.6    Zhang, Q.7
  • 24
    • 0020047427 scopus 로고
    • Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells
    • North, R. J., Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells. J. Exp. Med. 1982. 155: 1063-1074.
    • (1982) J. Exp. Med. , vol.155 , pp. 1063-1074
    • North, R.J.1
  • 25
    • 41149178490 scopus 로고    scopus 로고
    • Comparative methodologies of regulatory T cell depletion in a murine melanoma model
    • Matsushita, N., Pilon-Thomas, S. A., Martin, L. M. and Riker, A. I., Comparative methodologies of regulatory T cell depletion in a murine melanoma model. J. Immunol. Methods 2008. 333: 167-179.
    • (2008) J. Immunol. Methods , vol.333 , pp. 167-179
    • Matsushita, N.1    Pilon-Thomas, S.A.2    Martin, L.M.3    Riker, A.I.4
  • 26
    • 0035903324 scopus 로고    scopus 로고
    • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
    • Sutmuller, R. P., van Duivenvoorde, L. M., van Elsas, A., Schumacher, T. N., Wildenberg, M. E., Allison, J. P., Toes, R. E. et al., Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J. Exp. Med. 2001. 194: 823-832.
    • (2001) J. Exp. Med. , vol.194 , pp. 823-832
    • Sutmuller, R.P.1    van Duivenvoorde, L.M.2    van Elsas, A.3    Schumacher, T.N.4    Wildenberg, M.E.5    Allison, J.P.6    Toes, R.E.7
  • 27
    • 0036093489 scopus 로고    scopus 로고
    • Depletion of CD4+ CD25+ regulatory cells augments the generation of specific immune T cells in tumor-draining lymph nodes
    • Tanaka, H., Tanaka, J., Kjaergaard, J. and Shu, S., Depletion of CD4+ CD25+ regulatory cells augments the generation of specific immune T cells in tumor-draining lymph nodes. J. Immunother. 2002. 25: 207-217.
    • (2002) J. Immunother. , vol.25 , pp. 207-217
    • Tanaka, H.1    Tanaka, J.2    Kjaergaard, J.3    Shu, S.4
  • 28
    • 0033168037 scopus 로고    scopus 로고
    • Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody
    • Onizuka, S., Tawara, I., Shimizu, J., Sakaguchi, S., Fujita, T. and Nakayama, E., Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody. Cancer Res. 1999. 59: 3128-3133.
    • (1999) Cancer Res. , vol.59 , pp. 3128-3133
    • Onizuka, S.1    Tawara, I.2    Shimizu, J.3    Sakaguchi, S.4    Fujita, T.5    Nakayama, E.6
  • 29
    • 51049108540 scopus 로고    scopus 로고
    • Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma
    • Quezada, S. A., Peggs, K. S., Simpson, T. R., Shen, Y., Littman, D. R. and Allison, J. P., Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma. J. Exp. Med. 2008. 205: 2125-2138.
    • (2008) J. Exp. Med. , vol.205 , pp. 2125-2138
    • Quezada, S.A.1    Peggs, K.S.2    Simpson, T.R.3    Shen, Y.4    Littman, D.R.5    Allison, J.P.6
  • 30
    • 77951637543 scopus 로고    scopus 로고
    • Blockade of programmed death ligand 1 enhances the therapeutic efficacy of combination immunotherapy against melanoma
    • Pilon-Thomas, S., Mackay, A., Vohra, N. and Mule, J. J., Blockade of programmed death ligand 1 enhances the therapeutic efficacy of combination immunotherapy against melanoma. J. Immunol. 2010. 184: 3442-3449.
    • (2010) J. Immunol. , vol.184 , pp. 3442-3449
    • Pilon-Thomas, S.1    Mackay, A.2    Vohra, N.3    Mule, J.J.4
  • 31
    • 77949900562 scopus 로고    scopus 로고
    • Dendritic cells support homeostatic expansion of Foxp3+ regulatory T cells in Foxp3.LuciDTR mice
    • Suffner, J., Hochweller, K., Kuhnle, M. C., Li, X., Kroczek, R. A., Garbi, N. and Hammerling, G. J., Dendritic cells support homeostatic expansion of Foxp3+ regulatory T cells in Foxp3.LuciDTR mice. J. Immunol. 2010. 184: 1810-1820.
    • (2010) J. Immunol. , vol.184 , pp. 1810-1820
    • Suffner, J.1    Hochweller, K.2    Kuhnle, M.C.3    Li, X.4    Kroczek, R.A.5    Garbi, N.6    Hammerling, G.J.7
  • 32
    • 0036494443 scopus 로고    scopus 로고
    • Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication
    • Ganss, R., Ryschich, E., Klar, E., Arnold, B. and Hammerling, G. J., Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication. Cancer Res. 2002. 62: 1462-1470.
    • (2002) Cancer Res. , vol.62 , pp. 1462-1470
    • Ganss, R.1    Ryschich, E.2    Klar, E.3    Arnold, B.4    Hammerling, G.J.5
  • 33
    • 2442452552 scopus 로고    scopus 로고
    • CpG motifs as proinflammatory factors render autochthonous tumors permissive for infiltration and destruction
    • Garbi, N., Arnold, B., Gordon, S., Hammerling, G. J. and Ganss, R., CpG motifs as proinflammatory factors render autochthonous tumors permissive for infiltration and destruction. J. Immunol. 2004. 172: 5861-5869.
    • (2004) J. Immunol. , vol.172 , pp. 5861-5869
    • Garbi, N.1    Arnold, B.2    Gordon, S.3    Hammerling, G.J.4    Ganss, R.5
  • 34
    • 77955389719 scopus 로고    scopus 로고
    • Tumor masses support naive T cell infiltration, activation, and differentiation into effectors
    • Thompson, E. D., Enriquez, H. L., Fu, Y. X. and Engelhard, V. H., Tumor masses support naive T cell infiltration, activation, and differentiation into effectors. J. Exp. Med. 2010. 207: 1791-1804.
    • (2010) J. Exp. Med. , vol.207 , pp. 1791-1804
    • Thompson, E.D.1    Enriquez, H.L.2    Fu, Y.X.3    Engelhard, V.H.4
  • 35
    • 77953025991 scopus 로고    scopus 로고
    • CD4+FOXP3+ regulatory T cell depletion by low-dose cyclophosphamide prevents recurrence in patients with large condylomata acuminata after laser therapy
    • Cao, Y., Zhao, J., Yang, Z., Cai, Z., Zhang, B., Zhou, Y., Shen, G. X. et al., CD4+FOXP3+ regulatory T cell depletion by low-dose cyclophosphamide prevents recurrence in patients with large condylomata acuminata after laser therapy. Clin. Immunol. 2010. 136: 21-29.
    • (2010) Clin. Immunol. , vol.136 , pp. 21-29
    • Cao, Y.1    Zhao, J.2    Yang, Z.3    Cai, Z.4    Zhang, B.5    Zhou, Y.6    Shen, G.X.7
  • 36
    • 44949111435 scopus 로고    scopus 로고
    • Partial reduction of human FOXP3+ CD4 T cells in vivo after CD25-directed recombinant immunotoxin administration
    • Powell, D. J., Jr., Attia, P., Ghetie, V., Schindler, J., Vitetta, E. S. and Rosenberg, S. A., Partial reduction of human FOXP3+ CD4 T cells in vivo after CD25-directed recombinant immunotoxin administration. J. Immunother. 2008. 31: 189-198.
    • (2008) J. Immunother. , vol.31 , pp. 189-198
    • Powell Jr, D.J.1    Attia, P.2    Ghetie, V.3    Schindler, J.4    Vitetta, E.S.5    Rosenberg, S.A.6
  • 37
    • 50949115267 scopus 로고    scopus 로고
    • Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines
    • Morse, M. A., Hobeika, A. C., Osada, T., Serra, D., Niedzwiecki, D., Lyerly, H. K. and Clay, T. M., Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines. Blood 2008. 112: 610-618.
    • (2008) Blood , vol.112 , pp. 610-618
    • Morse, M.A.1    Hobeika, A.C.2    Osada, T.3    Serra, D.4    Niedzwiecki, D.5    Lyerly, H.K.6    Clay, T.M.7
  • 38
    • 30144444279 scopus 로고    scopus 로고
    • Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells
    • Dannull, J., Su, Z., Rizzieri, D., Yang, B. K., Coleman, D., Yancey, D., Zhang, A. et al., Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. J. Clin. Invest. 2005. 115: 3623-3633.
    • (2005) J. Clin. Invest. , vol.115 , pp. 3623-3633
    • Dannull, J.1    Su, Z.2    Rizzieri, D.3    Yang, B.K.4    Coleman, D.5    Yancey, D.6    Zhang, A.7
  • 39
    • 34247504608 scopus 로고    scopus 로고
    • Depletion of CD4+CD25+ human regulatory T cells in vivo: kinetics of Treg depletion and alterations in immune functions in vivo and in vitro
    • Mahnke, K., Schonfeld, K., Fondel, S., Ring, S., Karakhanova, S., Wiedemeyer, K., Bedke, T. et al., Depletion of CD4+CD25+ human regulatory T cells in vivo: kinetics of Treg depletion and alterations in immune functions in vivo and in vitro. Int. J. Cancer 2007. 120: 2723-2733.
    • (2007) Int. J. Cancer , vol.120 , pp. 2723-2733
    • Mahnke, K.1    Schonfeld, K.2    Fondel, S.3    Ring, S.4    Karakhanova, S.5    Wiedemeyer, K.6    Bedke, T.7
  • 40
    • 65249138318 scopus 로고    scopus 로고
    • Effect of anti-CD25 antibody daclizumab in the inhibition of inflammation and stabilization of disease progression in multiple sclerosis
    • Bielekova, B., Howard, T., Packer, A. N., Richert, N., Blevins, G., Ohayon, J., Waldmann, T. A. et al., Effect of anti-CD25 antibody daclizumab in the inhibition of inflammation and stabilization of disease progression in multiple sclerosis. Arch. Neurol. 2009. 66: 483-489.
    • (2009) Arch. Neurol. , vol.66 , pp. 483-489
    • Bielekova, B.1    Howard, T.2    Packer, A.N.3    Richert, N.4    Blevins, G.5    Ohayon, J.6    Waldmann, T.A.7
  • 41
    • 34548142973 scopus 로고    scopus 로고
    • Daclizumab phase II trial in relapsing and remitting multiple sclerosis: MRI and clinical results
    • Rose, J. W., Burns, J. B., Bjorklund, J., Klein, J., Watt, H. E. and Carlson, N. G., Daclizumab phase II trial in relapsing and remitting multiple sclerosis: MRI and clinical results. Neurology 2007. 69: 785-789.
    • (2007) Neurology , vol.69 , pp. 785-789
    • Rose, J.W.1    Burns, J.B.2    Bjorklund, J.3    Klein, J.4    Watt, H.E.5    Carlson, N.G.6
  • 42
    • 33846868833 scopus 로고    scopus 로고
    • Anti-Tac (daclizumab, Zenapax) in the treatment of leukemia, autoimmune diseases, and in the prevention of allograft rejection: a 25-year personal odyssey
    • Waldmann, T. A., Anti-Tac (daclizumab, Zenapax) in the treatment of leukemia, autoimmune diseases, and in the prevention of allograft rejection: a 25-year personal odyssey. J. Clin. Immunol. 2007. 27: 1-18.
    • (2007) J. Clin. Immunol. , vol.27 , pp. 1-18
    • Waldmann, T.A.1
  • 43
    • 0033392641 scopus 로고    scopus 로고
    • Daclizumab: a review of its use in the prevention of acute rejection in renal transplant recipients
    • Wiseman, L. R. and Faulds, D., Daclizumab: a review of its use in the prevention of acute rejection in renal transplant recipients. Drugs 1999. 58: 1029-1042.
    • (1999) Drugs , vol.58 , pp. 1029-1042
    • Wiseman, L.R.1    Faulds, D.2
  • 44
    • 29544451715 scopus 로고    scopus 로고
    • Anti-CD25 monoclonal antibody sequential immunosuppressive induction therapy in renal transplants with high risk of delayed graft function
    • Gonzalez, E., Gutierrez, E., Hernandez, Y., Rosello, G., Gutierrez, M. J., Martinez, E. G., Manzanera, M. J. et al., Anti-CD25 monoclonal antibody sequential immunosuppressive induction therapy in renal transplants with high risk of delayed graft function. Transplant Proc. 2005. 37: 3736-3737.
    • (2005) Transplant Proc. , vol.37 , pp. 3736-3737
    • Gonzalez, E.1    Gutierrez, E.2    Hernandez, Y.3    Rosello, G.4    Gutierrez, M.J.5    Martinez, E.G.6    Manzanera, M.J.7
  • 45
    • 70350496784 scopus 로고    scopus 로고
    • Clinical use of anti-CD25 antibody daclizumab to enhance immune responses to tumor antigen vaccination by targeting regulatory T cells
    • Rech, A. J. and Vonderheide, R. H., Clinical use of anti-CD25 antibody daclizumab to enhance immune responses to tumor antigen vaccination by targeting regulatory T cells. Ann. NY Acad. Sci. 2009. 1174: 99-106.
    • (2009) Ann. NY Acad. Sci. , vol.1174 , pp. 99-106
    • Rech, A.J.1    Vonderheide, R.H.2
  • 46
    • 0024354304 scopus 로고
    • Determination of subcutaneous tumor size in athymic (nude) mice
    • Tomayko, M. M. and Reynolds, C. P., Determination of subcutaneous tumor size in athymic (nude) mice. Cancer Chemother. Pharmacol. 1989. 24: 148-154.
    • (1989) Cancer Chemother. Pharmacol. , vol.24 , pp. 148-154
    • Tomayko, M.M.1    Reynolds, C.P.2
  • 47
    • 38449121832 scopus 로고    scopus 로고
    • Quantitative comparison of click beetle and firefly luciferases for in vivo bioluminescence imaging
    • Miloud, T., Henrich, C. and Hammerling, G. J., Quantitative comparison of click beetle and firefly luciferases for in vivo bioluminescence imaging. J. Biomed. Opt. 2007. 12: 054018.
    • (2007) J. Biomed. Opt. , vol.12 , pp. 054018
    • Miloud, T.1    Henrich, C.2    Hammerling, G.J.3


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