Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 17, 2010, Pages 8017-8022

  Pastorelli, Luca ^a,b,c   Garg, Rekha R ^a   Hoang, Sharon B ^a   Spina, Luisa ^b,c   Mattioli, Benedetta ^a   Scarpa, Melania ^d   Fiocchi, Claudio ^d   Vecchi, Maurizio ^b,c   Pizarro, Theresa T ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b IRCCS POLICLINICO SAN DONATO   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Anti TNF therapy; Inflammatory bowel disease; SAMP1 YitFc mouse model

Indexed keywords

BIOLOGICAL MARKER; INFLIXIMAB; INTERLEUKIN 17; INTERLEUKIN 33; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN RECEPTOR; ST2 RECEPTOR; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; COLON CROHN DISEASE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; TH1 CELL; TH2 CELL; ULCERATIVE COLITIS;

ANIMALS; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; CELLS, CULTURED; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATORY BOWEL DISEASES; INTERLEUKINS; INTESTINAL MUCOSA; LYMPH NODES; MICE; RECEPTORS, CELL SURFACE; T-LYMPHOCYTES, HELPER-INDUCER; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

MUS;

EID: 77952324145     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0912678107     Document Type: Article

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