메뉴 건너뛰기




Volumn 109, Issue 10, 2013, Pages 2629-2635

Intratumoral regulatory T cells upregulate immunosuppressive molecules in head and neck cancer patients

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8 CONCENTRATE; CD39 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; PROGRAMMED DEATH 1 RECEPTOR; TRANSCRIPTION FACTOR FOXP3;

EID: 84887832812     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2013.645     Document Type: Article
Times cited : (237)

References (28)
  • 3
    • 34547788180 scopus 로고    scopus 로고
    • A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
    • Coombes JL, Siddiqui KR, Arancibia-Carcamo CV, Hall J, Sun CM, Belkaid Y, Powrie F (2007) A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med 204: 1757-1764.
    • (2007) J Exp Med , vol.204 , pp. 1757-1764
    • Coombes, J.L.1    Siddiqui, K.R.2    Arancibia-Carcamo, C.V.3    Hall, J.4    Sun, C.M.5    Belkaid, Y.6    Powrie, F.7
  • 5
    • 84861783871 scopus 로고    scopus 로고
    • The prognostic value of FoxP3+ tumour-infiltrating lymphocytes in cancer: A critical review of the literature
    • deLeeuw RJ, Kost SE, Kakal JA, Nelson BH (2008) The prognostic value of FoxP3+ tumour-infiltrating lymphocytes in cancer: a critical review of the literature. Clin Cancer Res 18: 3022-3029.
    • (2008) Clin Cancer Res , vol.18 , pp. 3022-3029
    • Deleeuw, R.J.1    Kost, S.E.2    Kakal, J.A.3    Nelson, B.H.4
  • 6
    • 49249089425 scopus 로고    scopus 로고
    • Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways
    • Fife BT, Bluestone JA (2008) Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways. Immunol Rev 224: 166-182.
    • (2008) Immunol Rev , vol.224 , pp. 166-182
    • Fife, B.T.1    Bluestone, J.A.2
  • 7
    • 77953747963 scopus 로고    scopus 로고
    • The PD-1 pathway in tolerance and autoimmunity
    • Francisco LM, Sage PT, Sharpe AH (2010) The PD-1 pathway in tolerance and autoimmunity. Immunol Rev 236: 219-242.
    • (2010) Immunol Rev , vol.236 , pp. 219-242
    • Francisco, L.M.1    Sage, P.T.2    Sharpe, A.H.3
  • 9
    • 33749317518 scopus 로고    scopus 로고
    • Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions
    • Hiraoka N, Onozato K, Kosuge T, Hirohashi S (2006) Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions. Clin Cancer Res 12: 5423-5434.
    • (2006) Clin Cancer Res , vol.12 , pp. 5423-5434
    • Hiraoka, N.1    Onozato, K.2    Kosuge, T.3    Hirohashi, S.4
  • 10
    • 0141891466 scopus 로고    scopus 로고
    • Increased populations of regulatory T cells in peripheral blood and tumour-infiltrating lymphocytes in patients with gastric and esophageal cancers
    • Ichihara F, Kono K, Takahashi A, Kawaida H, Sugai H, Fujii H (2003) Increased populations of regulatory T cells in peripheral blood and tumour-infiltrating lymphocytes in patients with gastric and esophageal cancers. Clin Cancer Res 9: 4404-4408.
    • (2003) Clin Cancer Res , vol.9 , pp. 4404-4408
    • Ichihara, F.1    Kono, K.2    Takahashi, A.3    Kawaida, H.4    Sugai, H.5    Fujii, H.6
  • 11
    • 84862746826 scopus 로고    scopus 로고
    • Immune checkpoints in central nervous system autoimmunity
    • Joller N, Peters A, Anderson AC, Kuchroo VK (2012) Immune checkpoints in central nervous system autoimmunity. Immunol Rev 248: 122-139.
    • (2012) Immunol Rev , vol.248 , pp. 122-139
    • Joller, N.1    Peters, A.2    Anderson, A.C.3    Kuchroo, V.K.4
  • 15
    • 33746933828 scopus 로고    scopus 로고
    • TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling
    • Oida T, Xu L, Weiner HL, Kitani A, Strober W (2006) TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling. J Immunol 177: 2331-2339.
    • (2006) J Immunol , vol.177 , pp. 2331-2339
    • Oida, T.1    Xu, L.2    Weiner, H.L.3    Kitani, A.4    Strober, W.5
  • 16
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM (2012) The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 12: 252-264.
    • (2012) Nat Rev Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 17
    • 45549090382 scopus 로고    scopus 로고
    • Preferential costimulation by CD80 results in IL-10-dependent TGF-beta1(+)-adaptive regulatory T cell generation
    • Perez N, Karumuthil-Melethil S, Li R, Prabhakar BS, Holterman MJ, Vasu C (2008) Preferential costimulation by CD80 results in IL-10-dependent TGF-beta1(+)-adaptive regulatory T cell generation. J Immunol 180: 6566-6576.
    • (2008) J Immunol , vol.180 , pp. 6566-6576
    • Perez, N.1    Karumuthil-Melethil, S.2    Li, R.3    Prabhakar, B.S.4    Holterman, M.J.5    Vasu, C.6
  • 19
    • 84862801759 scopus 로고    scopus 로고
    • Program death-1 regulates peripheral T cell tolerance via an anergy-independent mechanism
    • Qiao G, Yang L, Li Z, Ying H, Hassen Y, Yin F, Zhang J (2012) Program death-1 regulates peripheral T cell tolerance via an anergy-independent mechanism. Clin Immunol 143: 128-133.
    • (2012) Clin Immunol , vol.143 , pp. 128-133
    • Qiao, G.1    Yang, L.2    Li, Z.3    Ying, H.4    Hassen, Y.5    Yin, F.6    Zhang, J.7
  • 20
    • 84863899032 scopus 로고    scopus 로고
    • The T-cell receptor repertoire of tumour-infiltrating regulatory T lymphocytes is skewed toward public sequences
    • Sainz-Perez A, Lim A, Lemercier B, Leclerc C (2012) The T-cell receptor repertoire of tumour-infiltrating regulatory T lymphocytes is skewed toward public sequences. Cancer Res 72: 3557-3569.
    • (2012) Cancer Res , vol.72 , pp. 3557-3569
    • Sainz-Perez, A.1    Lim, A.2    Lemercier, B.3    Leclerc, C.4
  • 21
    • 16244409219 scopus 로고    scopus 로고
    • Characteristics of CD4+ CD25+ regulatory T cells in the peripheral circulation of patients with head and neck cancer
    • Schaefer C, Kim GG, Albers A, Hoermann K, Myers EN, Whiteside TL (2005) Characteristics of CD4+ CD25+ regulatory T cells in the peripheral circulation of patients with head and neck cancer. Br J Cancer 92: 913-920.
    • (2005) Br J Cancer , vol.92 , pp. 913-920
    • Schaefer, C.1    Kim, G.G.2    Albers, A.3    Hoermann, K.4    Myers, E.N.5    Whiteside, T.L.6
  • 22
    • 84864005209 scopus 로고    scopus 로고
    • Phenotypic and functional characteristics of CD4+ CD39+ FOXP3+ and CD4+ CD39+ FOXP3neg T-cell subsets in cancer patients
    • Schuler PJ, Schilling B, Harasymczuk M, Hoffmann TK, Johnson J, Lang S, Whiteside TL (2012) Phenotypic and functional characteristics of CD4+ CD39+ FOXP3+ and CD4+ CD39+ FOXP3neg T-cell subsets in cancer patients. Eur J Immunol 42: 1876-1885.
    • (2012) Eur J Immunol , vol.42 , pp. 1876-1885
    • Schuler, P.J.1    Schilling, B.2    Harasymczuk, M.3    Hoffmann, T.K.4    Johnson, J.5    Lang, S.6    Whiteside, T.L.7
  • 23
    • 35948952840 scopus 로고    scopus 로고
    • The frequency and suppressor function of CD4+CD25highFoxp3+ T cells in the circulation of patients with squamous cell carcinoma of the head and neck
    • Strauss L, Bergmann C, Gooding W, Johnson JT, Whiteside TL (2007) The frequency and suppressor function of CD4+CD25highFoxp3+ T cells in the circulation of patients with squamous cell carcinoma of the head and neck. Clin Cancer Res 13: 6301-6311.
    • (2007) Clin Cancer Res , vol.13 , pp. 6301-6311
    • Strauss, L.1    Bergmann, C.2    Gooding, W.3    Johnson, J.T.4    Whiteside, T.L.5
  • 24
    • 34547757390 scopus 로고    scopus 로고
    • Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
    • Sun CM, Hall JA, Blank RB, Bouladoux N, Oukka M, Mora JR, Belkaid Y (2007) Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med 204: 1775-1785.
    • (2007) J Exp Med , vol.204 , pp. 1775-1785
    • Sun, C.M.1    Hall, J.A.2    Blank, R.B.3    Bouladoux, N.4    Oukka, M.5    Mora, J.R.6    Belkaid, Y.7
  • 26
    • 82255192901 scopus 로고    scopus 로고
    • The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses
    • Walker LS, Sansom DM (2011) The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses. Nat Rev Immunol 11: 852-863.
    • (2011) Nat Rev Immunol , vol.11 , pp. 852-863
    • Walker, L.S.1    Sansom, D.M.2
  • 28
    • 49649113444 scopus 로고    scopus 로고
    • Acquisition of suppressive function by activated human CD4+ CD25-T cells is associated with the expression of CTLA-4 not FoxP3
    • Zheng Y, Manzotti CN, Burke F, Dussably L, Qureshi O, Walker LS, Sansom DM (2008) Acquisition of suppressive function by activated human CD4+ CD25-T cells is associated with the expression of CTLA-4 not FoxP3. J Immunol 181: 1683-1691.
    • (2008) J Immunol , vol.181 , pp. 1683-1691
    • Zheng, Y.1    Manzotti, C.N.2    Burke, F.3    Dussably, L.4    Qureshi, O.5    Walker, L.S.6    Sansom, D.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.