-
1
-
-
0037203867
-
Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
-
Monney L, Sabatos CA, Gaglia JL, Ryu A, Waldner H, et al. (2002) Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature 415: 536-541.
-
(2002)
Nature
, vol.415
, pp. 536-541
-
-
Monney, L.1
Sabatos, C.A.2
Gaglia, J.L.3
Ryu, A.4
Waldner, H.5
-
2
-
-
0242708767
-
Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance
-
Sanchez-Fueyo A, Tian J, Picarella D, Domenig C, Zheng XX, et al. (2003) Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance. Nat Immunol 4: 1093-1101.
-
(2003)
Nat Immunol
, vol.4
, pp. 1093-1101
-
-
Sanchez-Fueyo, A.1
Tian, J.2
Picarella, D.3
Domenig, C.4
Zheng, X.X.5
-
3
-
-
0242539820
-
Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance
-
Sabatos CA, Chakravarti S, Cha E, Schubart A, Sanchez-Fueyo A, et al. (2003) Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance. Nat Immunol 4: 1102-1110.
-
(2003)
Nat Immunol
, vol.4
, pp. 1102-1110
-
-
Sabatos, C.A.1
Chakravarti, S.2
Cha, E.3
Schubart, A.4
Sanchez-Fueyo, A.5
-
4
-
-
30044434075
-
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
-
Zhu C, Anderson AC, Schubart A, Xiong H, Imitola J, et al. (2005) The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity. Nat Immunol 6: 1245-1252.
-
(2005)
Nat Immunol
, vol.6
, pp. 1245-1252
-
-
Zhu, C.1
Anderson, A.C.2
Schubart, A.3
Xiong, H.4
Imitola, J.5
-
5
-
-
33947224207
-
TIM-3 is expressed in melanoma cells and is upregulated in TGF-beta stimulated mast cells
-
Wiener Z, Kohalmi B, Pocza P, Jeager J, Tolgyesi G, et al. (2007) TIM-3 is expressed in melanoma cells and is upregulated in TGF-beta stimulated mast cells. J Invest Dermatol 127: 906-914.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 906-914
-
-
Wiener, Z.1
Kohalmi, B.2
Pocza, P.3
Jeager, J.4
Tolgyesi, G.5
-
6
-
-
84859192882
-
Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9
-
Gleason MK, Lenvik TR, McCullar V, Felices M, O'Brien MS, et al. (2012) Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9. Blood 119: 3064-3072.
-
(2012)
Blood
, vol.119
, pp. 3064-3072
-
-
Gleason, M.K.1
Lenvik, T.R.2
McCullar, V.3
Felices, M.4
O'Brien, M.S.5
-
7
-
-
79960918412
-
Emerging Tim-3 functions in antimicrobial and tumor immunity
-
Sakuishi K, Jayaraman P, Behar SM, Anderson AC, Kuchroo VK, (2011) Emerging Tim-3 functions in antimicrobial and tumor immunity. Trends Immunol 32: 345-349.
-
(2011)
Trends Immunol
, vol.32
, pp. 345-349
-
-
Sakuishi, K.1
Jayaraman, P.2
Behar, S.M.3
Anderson, A.C.4
Kuchroo, V.K.5
-
8
-
-
33745035874
-
Dysregulated T cell expression of TIM3 in multiple sclerosis
-
Koguchi K, Anderson DE, Yang L, O'Connor KC, Kuchroo VK, et al. (2006) Dysregulated T cell expression of TIM3 in multiple sclerosis. J Exp Med 203: 1413-1418.
-
(2006)
J Exp Med
, vol.203
, pp. 1413-1418
-
-
Koguchi, K.1
Anderson, D.E.2
Yang, L.3
O'Connor, K.C.4
Kuchroo, V.K.5
-
9
-
-
58149277359
-
Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
-
Jones RB, Ndhlovu LC, Barbour JD, Sheth PM, Jha AR, et al. (2008) Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection. J Exp Med 205: 2763-2779.
-
(2008)
J Exp Med
, vol.205
, pp. 2763-2779
-
-
Jones, R.B.1
Ndhlovu, L.C.2
Barbour, J.D.3
Sheth, P.M.4
Jha, A.R.5
-
10
-
-
65549147768
-
Blockade of Tim-3 pathway ameliorates interferon-gamma production from hepatic CD8+ T cells in a mouse model of hepatitis B virus infection
-
Ju Y, Hou N, Zhang XN, Zhao D, Liu Y, et al. (2009) Blockade of Tim-3 pathway ameliorates interferon-gamma production from hepatic CD8+ T cells in a mouse model of hepatitis B virus infection. Cell Mol Immunol 6: 35-43.
-
(2009)
Cell Mol Immunol
, vol.6
, pp. 35-43
-
-
Ju, Y.1
Hou, N.2
Zhang, X.N.3
Zhao, D.4
Liu, Y.5
-
11
-
-
84860347302
-
Blockade of Tim-3 signaling restores the virus-specific CD8(+) T-cell response in patients with chronic hepatitis B. Eur J Immunol
-
Wu W, Shi Y, Li S, Zhang Y, Liu Y, et al. (2012) Blockade of Tim-3 signaling restores the virus-specific CD8(+) T-cell response in patients with chronic hepatitis B. Eur J Immunol. 42: 1180-1191.
-
(2012)
, vol.42
, pp. 1180-1191
-
-
Wu, W.1
Shi, Y.2
Li, S.3
Zhang, Y.4
Liu, Y.5
-
12
-
-
69449091993
-
Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells
-
Golden-Mason L, Palmer BE, Kassam N, Townshend-Bulson L, Livingston S, et al. (2009) Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells. J Virol 83: 9122-9130.
-
(2009)
J Virol
, vol.83
, pp. 9122-9130
-
-
Golden-Mason, L.1
Palmer, B.E.2
Kassam, N.3
Townshend-Bulson, L.4
Livingston, S.5
-
13
-
-
77954053238
-
Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response
-
Sehrawat S, Reddy PB, Rajasagi N, Suryawanshi A, Hirashima M, et al. (2010) Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response. PLoS Pathog 6: e1000882.
-
(2010)
PLoS Pathog
, vol.6
-
-
Sehrawat, S.1
Reddy, P.B.2
Rajasagi, N.3
Suryawanshi, A.4
Hirashima, M.5
-
14
-
-
84863549067
-
Allograft rejection is restrained by short-lived TIM-3+PD-1+Foxp3+ Tregs
-
Gupta S, Thornley TB, Gao W, Larocca R, Turka LA, et al. (2012) Allograft rejection is restrained by short-lived TIM-3+PD-1+Foxp3+ Tregs. J Clin Invest 122: 2395-2404.
-
(2012)
J Clin Invest
, vol.122
, pp. 2395-2404
-
-
Gupta, S.1
Thornley, T.B.2
Gao, W.3
Larocca, R.4
Turka, L.A.5
-
15
-
-
84863630845
-
Tim-3 pathway controls regulatory and effector T cell balance during hepatitis C virus infection
-
Moorman JP, Wang JM, Zhang Y, Ji XJ, Ma CJ, et al. (2012) Tim-3 pathway controls regulatory and effector T cell balance during hepatitis C virus infection. J Immunol 189: 755-766.
-
(2012)
J Immunol
, vol.189
, pp. 755-766
-
-
Moorman, J.P.1
Wang, J.M.2
Zhang, Y.3
Ji, X.J.4
Ma, C.J.5
-
16
-
-
84867144615
-
Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinoma
-
Li H, Wu K, Tao K, Chen L, Zheng Q, et al. (2012) Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinoma. Hepatology 56: 1342-1351.
-
(2012)
Hepatology
, vol.56
, pp. 1342-1351
-
-
Li, H.1
Wu, K.2
Tao, K.3
Chen, L.4
Zheng, Q.5
-
17
-
-
77957744369
-
Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
-
Sakuishi K, Apetoh L, Sullivan JM, Blazar BR, Kuchroo VK, et al. (2010) Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity. J Exp Med 207: 2187-2194.
-
(2010)
J Exp Med
, vol.207
, pp. 2187-2194
-
-
Sakuishi, K.1
Apetoh, L.2
Sullivan, J.M.3
Blazar, B.R.4
Kuchroo, V.K.5
-
18
-
-
84857159981
-
TIM-3 expression characterizes regulatory T cells in tumor tissues and is associated with lung cancer progression
-
Gao X, Zhu Y, Li G, Huang H, Zhang G, et al. (2012) TIM-3 expression characterizes regulatory T cells in tumor tissues and is associated with lung cancer progression. PLoS One 7: e30676.
-
(2012)
PLoS One
, vol.7
-
-
Gao, X.1
Zhu, Y.2
Li, G.3
Huang, H.4
Zhang, G.5
-
19
-
-
77957723967
-
Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients
-
Fourcade J, Sun Z, Benallaoua M, Guillaume P, Luescher IF, et al. (2010) Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients. J Exp Med 207: 2175-2186.
-
(2010)
J Exp Med
, vol.207
, pp. 2175-2186
-
-
Fourcade, J.1
Sun, Z.2
Benallaoua, M.3
Guillaume, P.4
Luescher, I.F.5
-
20
-
-
84859701005
-
IL-12 upregulates TIM-3 expression and induces T cell exhaustion in patients with follicular B cell non-Hodgkin lymphoma
-
Yang ZZ, Grote DM, Ziesmer SC, Niki T, Hirashima M, et al. (2012) IL-12 upregulates TIM-3 expression and induces T cell exhaustion in patients with follicular B cell non-Hodgkin lymphoma. J Clin Invest 122: 1271-1282.
-
(2012)
J Clin Invest
, vol.122
, pp. 1271-1282
-
-
Yang, Z.Z.1
Grote, D.M.2
Ziesmer, S.C.3
Niki, T.4
Hirashima, M.5
-
21
-
-
77956409684
-
Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells
-
Dardalhon V, Anderson AC, Karman J, Apetoh L, Chandwaskar R, et al. (2010) Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells. J Immunol 185: 1383-1392.
-
(2010)
J Immunol
, vol.185
, pp. 1383-1392
-
-
Dardalhon, V.1
Anderson, A.C.2
Karman, J.3
Apetoh, L.4
Chandwaskar, R.5
-
22
-
-
19944430491
-
Tim-3+ T-bet+ tumor-specific Th1 cells colocalize with and inhibit development and growth of murine neoplasms
-
Simmons WJ, Koneru M, Mohindru M, Thomas R, Cutro S, et al. (2005) Tim-3+ T-bet+ tumor-specific Th1 cells colocalize with and inhibit development and growth of murine neoplasms. J Immunol 174: 1405-1415.
-
(2005)
J Immunol
, vol.174
, pp. 1405-1415
-
-
Simmons, W.J.1
Koneru, M.2
Mohindru, M.3
Thomas, R.4
Cutro, S.5
-
23
-
-
31144474853
-
Soluble form of T cell Ig mucin 3 is an inhibitory molecule in T cell-mediated immune response
-
Geng H, Zhang GM, Li D, Zhang H, Yuan Y, et al. (2006) Soluble form of T cell Ig mucin 3 is an inhibitory molecule in T cell-mediated immune response. J Immunol 176: 1411-1420.
-
(2006)
J Immunol
, vol.176
, pp. 1411-1420
-
-
Geng, H.1
Zhang, G.M.2
Li, D.3
Zhang, H.4
Yuan, Y.5
-
24
-
-
71849095178
-
Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions
-
Nagahara K, Arikawa T, Oomizu S, Kontani K, Nobumoto A, et al. (2008) Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions. J Immunol 181: 7660-7669.
-
(2008)
J Immunol
, vol.181
, pp. 7660-7669
-
-
Nagahara, K.1
Arikawa, T.2
Oomizu, S.3
Kontani, K.4
Nobumoto, A.5
-
25
-
-
64549108462
-
Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients
-
Zhang JP, Yan J, Xu J, Pang XH, Chen MS, et al. (2009) Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients. J Hepatol 50: 980-989.
-
(2009)
J Hepatol
, vol.50
, pp. 980-989
-
-
Zhang, J.P.1
Yan, J.2
Xu, J.3
Pang, X.H.4
Chen, M.S.5
-
26
-
-
67449110979
-
Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1
-
Kuang DM, Zhao Q, Peng C, Xu J, Zhang JP, et al. (2009) Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1. J Exp Med 206: 1327-1337.
-
(2009)
J Exp Med
, vol.206
, pp. 1327-1337
-
-
Kuang, D.M.1
Zhao, Q.2
Peng, C.3
Xu, J.4
Zhang, J.P.5
-
27
-
-
73449111925
-
Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells
-
Kuang DM, Peng C, Zhao Q, Wu Y, Chen MS, et al. (2010) Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells. Hepatology 51: 154-164.
-
(2010)
Hepatology
, vol.51
, pp. 154-164
-
-
Kuang, D.M.1
Peng, C.2
Zhao, Q.3
Wu, Y.4
Chen, M.S.5
-
28
-
-
68549136586
-
Increased intratumoral regulatory T cells are related to intratumoral macrophages and poor prognosis in hepatocellular carcinoma patients
-
Zhou J, Ding T, Pan W, Zhu LY, Li L, et al. (2009) Increased intratumoral regulatory T cells are related to intratumoral macrophages and poor prognosis in hepatocellular carcinoma patients. Int J Cancer 125: 1640-1648.
-
(2009)
Int J Cancer
, vol.125
, pp. 1640-1648
-
-
Zhou, J.1
Ding, T.2
Pan, W.3
Zhu, L.Y.4
Li, L.5
-
29
-
-
34250005419
-
Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients
-
Fu J, Xu D, Liu Z, Shi M, Zhao P, et al. (2007) Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients. Gastroenterology 132: 2328-2339.
-
(2007)
Gastroenterology
, vol.132
, pp. 2328-2339
-
-
Fu, J.1
Xu, D.2
Liu, Z.3
Shi, M.4
Zhao, P.5
-
30
-
-
33645286546
-
Regulatory T cells, tumour immunity and immunotherapy
-
Zou W, (2006) Regulatory T cells, tumour immunity and immunotherapy. Nat Rev Immunol 6: 295-307.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 295-307
-
-
Zou, W.1
-
31
-
-
84866098957
-
The development and function of follicular helper T cells in immune responses
-
Chen M, Guo Z, Ju W, Ryffel B, He X, et al. (2012) The development and function of follicular helper T cells in immune responses. Cell Mol Immunol 9: 375-379.
-
(2012)
Cell Mol Immunol
, vol.9
, pp. 375-379
-
-
Chen, M.1
Guo, Z.2
Ju, W.3
Ryffel, B.4
He, X.5
-
32
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
-
Biswas SK, Mantovani A, (2010) Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol 11: 889-896.
-
(2010)
Nat Immunol
, vol.11
, pp. 889-896
-
-
Biswas, S.K.1
Mantovani, A.2
-
33
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, et al. (2000) A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100: 655-669.
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
Kim, S.T.2
Costa, G.L.3
Zhang, X.4
Fathman, C.G.5
-
34
-
-
33847401888
-
Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasion
-
Blank C, Mackensen A, (2007) Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasion. Cancer Immunol Immunother 56: 739-745.
-
(2007)
Cancer Immunol Immunother
, vol.56
, pp. 739-745
-
-
Blank, C.1
Mackensen, A.2
-
35
-
-
42649125225
-
PD-1 and its ligands in tolerance and immunity
-
Keir ME, Butte MJ, Freeman GJ, Sharpe AH, (2008) PD-1 and its ligands in tolerance and immunity. Annu Rev Immunol 26: 677-704.
-
(2008)
Annu Rev Immunol
, vol.26
, pp. 677-704
-
-
Keir, M.E.1
Butte, M.J.2
Freeman, G.J.3
Sharpe, A.H.4
-
36
-
-
33745813929
-
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
-
Seddiki N, Santner-Nanan B, Martinson J, Zaunders J, Sasson S, et al. (2006) Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 203: 1693-1700.
-
(2006)
J Exp Med
, vol.203
, pp. 1693-1700
-
-
Seddiki, N.1
Santner-Nanan, B.2
Martinson, J.3
Zaunders, J.4
Sasson, S.5
-
37
-
-
33745817085
-
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
-
Liu W, Putnam AL, Xu-Yu Z, Szot GL, Lee MR, et al. (2006) CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med 203: 1701-1711.
-
(2006)
J Exp Med
, vol.203
, pp. 1701-1711
-
-
Liu, W.1
Putnam, A.L.2
Xu-Yu, Z.3
Szot, G.L.4
Lee, M.R.5
-
38
-
-
77954141914
-
FOXP3+ regulatory T cells in the human immune system
-
Sakaguchi S, Miyara M, Costantino CM, Hafler DA, (2010) FOXP3+ regulatory T cells in the human immune system. Nat Rev Immunol 10: 490-500.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 490-500
-
-
Sakaguchi, S.1
Miyara, M.2
Costantino, C.M.3
Hafler, D.A.4
-
39
-
-
34247277666
-
Foxp3 in control of the regulatory T cell lineage
-
Zheng Y, Rudensky AY, (2007) Foxp3 in control of the regulatory T cell lineage. Nat Immunol 8: 457-462.
-
(2007)
Nat Immunol
, vol.8
, pp. 457-462
-
-
Zheng, Y.1
Rudensky, A.Y.2
-
40
-
-
27644503683
-
CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy
-
Li L, Godfrey WR, Porter SB, Ge Y, June CH, et al. (2005) CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy. Blood 106: 3068-3073.
-
(2005)
Blood
, vol.106
, pp. 3068-3073
-
-
Li, L.1
Godfrey, W.R.2
Porter, S.B.3
Ge, Y.4
June, C.H.5
-
42
-
-
79951632624
-
Antigen-non-specific regulation centered on CD25+Foxp3+ Treg cells
-
Hu G, Liu Z, Zheng C, Zheng SG, (2010) Antigen-non-specific regulation centered on CD25+Foxp3+ Treg cells. Cell Mol Immunol 7: 414-418.
-
(2010)
Cell Mol Immunol
, vol.7
, pp. 414-418
-
-
Hu, G.1
Liu, Z.2
Zheng, C.3
Zheng, S.G.4
-
43
-
-
84860521444
-
The next challenge in cancer immunotherapy: controlling T-cell traffic to the tumor
-
Abastado JP, (2012) The next challenge in cancer immunotherapy: controlling T-cell traffic to the tumor. Cancer Res 72: 2159-2161.
-
(2012)
Cancer Res
, vol.72
, pp. 2159-2161
-
-
Abastado, J.P.1
-
45
-
-
84874574406
-
Ex vivo expansion of tumor-infiltrating lymphocytes from nasopharyngeal carcinoma patients for adoptive immunotherapy
-
He J, Tang XF, Chen QY, Mai HQ, Huang ZF, et al. (2012) Ex vivo expansion of tumor-infiltrating lymphocytes from nasopharyngeal carcinoma patients for adoptive immunotherapy. Chin J Cancer 31: 287-294.
-
(2012)
Chin J Cancer
, vol.31
, pp. 287-294
-
-
He, J.1
Tang, X.F.2
Chen, Q.Y.3
Mai, H.Q.4
Huang, Z.F.5
-
46
-
-
0036569127
-
Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation
-
Woo EY, Yeh H, Chu CS, Schlienger K, Carroll RG, et al. (2002) Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation. J Immunol 168: 4272-4276.
-
(2002)
J Immunol
, vol.168
, pp. 4272-4276
-
-
Woo, E.Y.1
Yeh, H.2
Chu, C.S.3
Schlienger, K.4
Carroll, R.G.5
-
47
-
-
62449250053
-
Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome
-
Gobert M, Treilleux I, Bendriss-Vermare N, Bachelot T, Goddard-Leon S, et al. (2009) Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome. Cancer Res 69: 2000-2009.
-
(2009)
Cancer Res
, vol.69
, pp. 2000-2009
-
-
Gobert, M.1
Treilleux, I.2
Bendriss-Vermare, N.3
Bachelot, T.4
Goddard-Leon, S.5
-
48
-
-
33644548654
-
Regulated compartmentalization of programmed cell death-1 discriminates CD4+CD25+ resting regulatory T cells from activated T cells
-
Raimondi G, Shufesky WJ, Tokita D, Morelli AE, Thomson AW, (2006) Regulated compartmentalization of programmed cell death-1 discriminates CD4+CD25+ resting regulatory T cells from activated T cells. J Immunol 176: 2808-2816.
-
(2006)
J Immunol
, vol.176
, pp. 2808-2816
-
-
Raimondi, G.1
Shufesky, W.J.2
Tokita, D.3
Morelli, A.E.4
Thomson, A.W.5
-
49
-
-
77949793555
-
A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection
-
Mengshol JA, Golden-Mason L, Arikawa T, Smith M, Niki T, et al. (2010) A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection. PLoS One 5: e9504.
-
(2010)
PLoS One
, vol.5
-
-
Mengshol, J.A.1
Golden-Mason, L.2
Arikawa, T.3
Smith, M.4
Niki, T.5
-
50
-
-
40849120400
-
Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
-
Seki M, Oomizu S, Sakata KM, Sakata A, Arikawa T, et al. (2008) Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin Immunol 127: 78-88.
-
(2008)
Clin Immunol
, vol.127
, pp. 78-88
-
-
Seki, M.1
Oomizu, S.2
Sakata, K.M.3
Sakata, A.4
Arikawa, T.5
-
51
-
-
80155127321
-
Prospects for TIM3-Targeted Antitumor Immunotherapy
-
Ngiow SF, Teng MW, Smyth MJ, (2011) Prospects for TIM3-Targeted Antitumor Immunotherapy. Cancer Res 71: 6567-6571.
-
(2011)
Cancer Res
, vol.71
, pp. 6567-6571
-
-
Ngiow, S.F.1
Teng, M.W.2
Smyth, M.J.3
-
52
-
-
84859157752
-
Tim-3, a negative regulator of anti-tumor immunity
-
Anderson AC, (2012) Tim-3, a negative regulator of anti-tumor immunity. Curr Opin Immunol 24: 213-216.
-
(2012)
Curr Opin Immunol
, vol.24
, pp. 213-216
-
-
Anderson, A.C.1
-
53
-
-
84858800620
-
The immune contexture in human tumours: impact on clinical outcome
-
Fridman WH, Pages F, Sautes-Fridman C, Galon J, (2012) The immune contexture in human tumours: impact on clinical outcome. Nat Rev Cancer 12: 298-306.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 298-306
-
-
Fridman, W.H.1
Pages, F.2
Sautes-Fridman, C.3
Galon, J.4
-
54
-
-
78049252250
-
CD56 negative NK cells: origin, function, and role in chronic viral disease
-
Bjorkstrom NK, Ljunggren HG, Sandberg JK, (2010) CD56 negative NK cells: origin, function, and role in chronic viral disease. Trends Immunol 31: 401-406.
-
(2010)
Trends Immunol
, vol.31
, pp. 401-406
-
-
Bjorkstrom, N.K.1
Ljunggren, H.G.2
Sandberg, J.K.3
-
55
-
-
79960428190
-
Tumor stroma reaction-related gene signature predicts clinical outcome in human hepatocellular carcinoma
-
Gao Q, Wang XY, Qiu SJ, Zhou J, Shi YH, et al. (2011) Tumor stroma reaction-related gene signature predicts clinical outcome in human hepatocellular carcinoma. Cancer Sci 102: 1522-1531.
-
(2011)
Cancer Sci
, vol.102
, pp. 1522-1531
-
-
Gao, Q.1
Wang, X.Y.2
Qiu, S.J.3
Zhou, J.4
Shi, Y.H.5
-
56
-
-
84863393290
-
CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1
-
Fourcade J, Sun Z, Pagliano O, Guillaume P, Luescher IF, et al. (2012) CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1. Cancer Res 72: 887-896.
-
(2012)
Cancer Res
, vol.72
, pp. 887-896
-
-
Fourcade, J.1
Sun, Z.2
Pagliano, O.3
Guillaume, P.4
Luescher, I.F.5
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