-
1
-
-
79955694765
-
Obesity and socioeconomic status in children and adolescents: United States, 2005-2008
-
Ogden CL, Lamb MM, Carroll MD, Flegal KM. Obesity and socioeconomic status in children and adolescents: United States, 2005-2008. NCHS Data Brief (2010) (51):1-8
-
(2010)
NCHS Data Brief
, Issue.51
, pp. 1-8
-
-
Ogden, C.L.1
Lamb, M.M.2
Carroll, M.D.3
Flegal, K.M.4
-
2
-
-
33846422032
-
Obesity and diabetes in the developing world-a growing challenge
-
Hossain P, Kawar B, El Nahas M. Obesity and diabetes in the developing world-a growing challenge. N Engl J Med (2007) 356(3):213-5. doi:10.1056/NEJMp068177
-
(2007)
N Engl J Med
, vol.356
, Issue.3
, pp. 213-215
-
-
Hossain, P.1
Kawar, B.2
El Nahas, M.3
-
3
-
-
33745775434
-
Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis
-
Sartor RB. Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis. Nat Clin Pract Gastroenterol Hepatol (2006) 3(7):390-407. doi:10.1038/ncpgasthep0528
-
(2006)
Nat Clin Pract Gastroenterol Hepatol
, vol.3
, Issue.7
, pp. 390-407
-
-
Sartor, R.B.1
-
4
-
-
15744400763
-
Distribution of major health risks: findings from the Global Burden of Disease study
-
Rodgers A, Ezzati M, Vander Hoorn S, Lopez AD, Lin RB, Murray CJ, et al. Distribution of major health risks: findings from the Global Burden of Disease study. PLoS Med (2004) 1(1):e27. doi:10.1371/journal.pmed.0010027
-
(2004)
PLoS Med
, vol.1
, Issue.1
-
-
Rodgers, A.1
Ezzati, M.2
Vander Hoorn, S.3
Lopez, A.D.4
Lin, R.B.5
Murray, C.J.6
-
5
-
-
33845866857
-
Inflammation and metabolic disorders
-
Hotamisligil GS. Inflammation and metabolic disorders. Nature (2006) 444(7121):860-7. doi:10.1038/nature05485
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
6
-
-
84946753563
-
The incretin effect in critically ill patients: a case-control study
-
Nielsen ST, Janum S, Krogh-Madsen R, Solomon TP, Møller K. The incretin effect in critically ill patients: a case-control study. Crit Care (2015) 19(1):402. doi:10.1186/s13054-015-1118-z
-
(2015)
Crit Care
, vol.19
, Issue.1
, pp. 402
-
-
Nielsen, S.T.1
Janum, S.2
Krogh-Madsen, R.3
Solomon, T.P.4
Møller, K.5
-
7
-
-
84928244016
-
Gliptin and GLP-1 analog treatment improves survival and vascular inflammation/dysfunction in animals with lipopolysaccharide-induced endotoxemia
-
Steven S, Hausding M, Kröller-Schön S, Mader M, Mikhed Y, Stamm P, et al. Gliptin and GLP-1 analog treatment improves survival and vascular inflammation/dysfunction in animals with lipopolysaccharide-induced endotoxemia. Basic Res Cardiol (2015) 110(2):6. doi:10.1007/s00395-015-0465-x
-
(2015)
Basic Res Cardiol
, vol.110
, Issue.2
, pp. 6
-
-
Steven, S.1
Hausding, M.2
Kröller-Schön, S.3
Mader, M.4
Mikhed, Y.5
Stamm, P.6
-
8
-
-
80052546811
-
Inflammation and cellular stress: a mechanistic link between immune-mediated and metabolically driven pathologies
-
Rath E, Haller D. Inflammation and cellular stress: a mechanistic link between immune-mediated and metabolically driven pathologies. Eur J Nutr (2011) 50(4):219-33. doi:10.1007/s00394-011-0197-0
-
(2011)
Eur J Nutr
, vol.50
, Issue.4
, pp. 219-233
-
-
Rath, E.1
Haller, D.2
-
9
-
-
84925873107
-
Immune regulation of metabolic homeostasis in health and disease
-
Brestoff JR, Artis D. Immune regulation of metabolic homeostasis in health and disease. Cell (2015) 161(1):146-60. doi:10.1016/j.cell.2015.02.022
-
(2015)
Cell
, vol.161
, Issue.1
, pp. 146-160
-
-
Brestoff, J.R.1
Artis, D.2
-
10
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science (1993) 259(5091):87-91. doi:10.1126/science.7678183
-
(1993)
Science
, vol.259
, Issue.5091
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
11
-
-
84922017739
-
Intestinal microbiota in metabolic diseases: from bacterial community structure and functions to species of pathophysiological relevance
-
Clavel T, Desmarchelier C, Haller D, Gérard P, Rohn S, Lepage P, et al. Intestinal microbiota in metabolic diseases: from bacterial community structure and functions to species of pathophysiological relevance. Gut Microbes (2014) 5(4):544-51. doi:10.4161/gmic.29331
-
(2014)
Gut Microbes
, vol.5
, Issue.4
, pp. 544-551
-
-
Clavel, T.1
Desmarchelier, C.2
Haller, D.3
Gérard, P.4
Rohn, S.5
Lepage, P.6
-
12
-
-
34548612724
-
Bacteria- and host-derived mechanisms to control intestinal epithelial cell homeostasis: implications for chronic inflammation
-
Clavel T, Haller D. Bacteria- and host-derived mechanisms to control intestinal epithelial cell homeostasis: implications for chronic inflammation. Inflamm Bowel Dis (2007) 13(9):1153-64. doi:10.1002/ibd.20174
-
(2007)
Inflamm Bowel Dis
, vol.13
, Issue.9
, pp. 1153-1164
-
-
Clavel, T.1
Haller, D.2
-
13
-
-
84901506886
-
Surface area of the digestive tract-revisited
-
Helander HF, Fandriks L. Surface area of the digestive tract-revisited. Scand J Gastroenterol (2014) 49(6):681-9. doi:10.3109/00365521.2014.898326
-
(2014)
Scand J Gastroenterol
, vol.49
, Issue.6
, pp. 681-689
-
-
Helander, H.F.1
Fandriks, L.2
-
14
-
-
84938812082
-
The intestinal immunoendocrine axis: novel cross-talk between enteroendocrine cells and the immune system during infection and inflammatory disease
-
Worthington JJ. The intestinal immunoendocrine axis: novel cross-talk between enteroendocrine cells and the immune system during infection and inflammatory disease. Biochem Soc Trans (2015) 43(4):727-33. doi:10.1042/BST20150090
-
(2015)
Biochem Soc Trans
, vol.43
, Issue.4
, pp. 727-733
-
-
Worthington, J.J.1
-
15
-
-
84942781740
-
Intestinal nutrient sensing and blood glucose control
-
Zietek T, Daniel H. Intestinal nutrient sensing and blood glucose control. Curr Opin Clin Nutr Metab Care (2015) 18(4):381-8. doi:10.1097/MCO.0000000000000187
-
(2015)
Curr Opin Clin Nutr Metab Care
, vol.18
, Issue.4
, pp. 381-388
-
-
Zietek, T.1
Daniel, H.2
-
16
-
-
84862743498
-
Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry
-
Habib AM, Richards P, Cairns LS, Rogers GJ, Bannon CA, Parker HE, et al. Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry. Endocrinology (2012) 153(7):3054-65. doi:10.1210/en.2011-2170
-
(2012)
Endocrinology
, vol.153
, Issue.7
, pp. 3054-3065
-
-
Habib, A.M.1
Richards, P.2
Cairns, L.S.3
Rogers, G.J.4
Bannon, C.A.5
Parker, H.E.6
-
17
-
-
84870225450
-
A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin
-
Egerod KL, Engelstoft MS, Grunddal KV, Nøhr MK, Secher A, Sakata I, et al. A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin. Endocrinology (2012) 153(12):5782-95. doi:10.1210/en.2012-1595
-
(2012)
Endocrinology
, vol.153
, Issue.12
, pp. 5782-5795
-
-
Egerod, K.L.1
Engelstoft, M.S.2
Grunddal, K.V.3
Nøhr, M.K.4
Secher, A.5
Sakata, I.6
-
18
-
-
84907059371
-
Duodenal CCK cells from male mice express multiple hormones including ghrelin
-
Sykaras AG, Demenis C, Cheng L, Pisitkun T, Mclaughlin JT, Fenton RA, et al. Duodenal CCK cells from male mice express multiple hormones including ghrelin. Endocrinology (2014) 155(9):3339-51. doi:10.1210/en.2013-2165
-
(2014)
Endocrinology
, vol.155
, Issue.9
, pp. 3339-3351
-
-
Sykaras, A.G.1
Demenis, C.2
Cheng, L.3
Pisitkun, T.4
Mclaughlin, J.T.5
Fenton, R.A.6
-
19
-
-
84958620086
-
Enteroendocrine cells: chemosensors in the intestinal epithelium
-
Gribble FM, Reimann F. Enteroendocrine cells: chemosensors in the intestinal epithelium. Annu Rev Physiol (2016) 78:277-99. doi:10.1146/annurev-physiol-021115-105439
-
(2016)
Annu Rev Physiol
, vol.78
, pp. 277-299
-
-
Gribble, F.M.1
Reimann, F.2
-
20
-
-
79952510102
-
Luminal amino acid-sensing cells in gastric mucosa
-
Nakamura E, Hasumura M, Uneyama H, Torii K. Luminal amino acid-sensing cells in gastric mucosa. Digestion (2011) 83(Suppl 1):13-8. doi:10.1159/000323399
-
(2011)
Digestion
, vol.83
, pp. 13-18
-
-
Nakamura, E.1
Hasumura, M.2
Uneyama, H.3
Torii, K.4
-
21
-
-
34347389492
-
GPR93 activation by protein hydrolysate induces CCK transcription and secretion in STC-1 cells
-
Choi S, Lee M, Shiu AL, Yo SJ, Halldén G, Aponte GW. GPR93 activation by protein hydrolysate induces CCK transcription and secretion in STC-1 cells. Am J Physiol Gastrointest Liver Physiol (2007) 292(5):G1366-75. doi:10.1152/ajpgi.00516.2006
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.292
, Issue.5
, pp. G1366-G1375
-
-
Choi, S.1
Lee, M.2
Shiu, A.L.3
Yo, S.J.4
Halldén, G.5
Aponte, G.W.6
-
22
-
-
84874040640
-
The G protein-coupled receptor family C group 6 subtype A (GPRC6A) receptor is involved in amino acid-induced glucagon-like peptide-1 secretion from GLUTag cells
-
Oya M, Kitaguchi T, Pais R, Reimann F, Gribble F, Tsuboi T. The G protein-coupled receptor family C group 6 subtype A (GPRC6A) receptor is involved in amino acid-induced glucagon-like peptide-1 secretion from GLUTag cells. J Biol Chem (2013) 288(7):4513-21. doi:10.1074/jbc.M112.402677
-
(2013)
J Biol Chem
, vol.288
, Issue.7
, pp. 4513-4521
-
-
Oya, M.1
Kitaguchi, T.2
Pais, R.3
Reimann, F.4
Gribble, F.5
Tsuboi, T.6
-
23
-
-
80054787845
-
Umami receptor activation increases duodenal bicarbonate secretion via glucagon-like peptide-2 release in rats
-
Wang JH, Inoue T, Higashiyama M, Guth PH, Engel E, Kaunitz JD, et al. Umami receptor activation increases duodenal bicarbonate secretion via glucagon-like peptide-2 release in rats. J Pharmacol Exp Ther (2011) 339(2):464-73. doi:10.1124/jpet.111.184788
-
(2011)
J Pharmacol Exp Ther
, vol.339
, Issue.2
, pp. 464-473
-
-
Wang, J.H.1
Inoue, T.2
Higashiyama, M.3
Guth, P.H.4
Engel, E.5
Kaunitz, J.D.6
-
24
-
-
35448995622
-
T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1
-
Margolskee RF, Dyer J, Kokrashvili Z, Salmon KS, Ilegems E, Daly K, et al. T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1. Proc Natl Acad Sci U S A (2007) 104(38):15075-80. doi:10.1073/pnas.0706678104
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.38
, pp. 15075-15080
-
-
Margolskee, R.F.1
Dyer, J.2
Kokrashvili, Z.3
Salmon, K.S.4
Ilegems, E.5
Daly, K.6
-
25
-
-
84994632130
-
Lipid-rich diet enhances L-cell density in obese subjects and in mice through improved L-cell differentiation
-
Aranias T, Grosfeld A, Poitou C, Omar AA, Le Gall M, Miquel S, et al. Lipid-rich diet enhances L-cell density in obese subjects and in mice through improved L-cell differentiation. J Nutr Sci (2015) 4:e22. doi:10.1017/jns.2015.11
-
(2015)
J Nutr Sci
, vol.4
-
-
Aranias, T.1
Grosfeld, A.2
Poitou, C.3
Omar, A.A.4
Le Gall, M.5
Miquel, S.6
-
26
-
-
80053459477
-
Gustatory and extragustatory functions of mammalian taste receptors
-
Behrens M, Meyerhof W. Gustatory and extragustatory functions of mammalian taste receptors. Physiol Behav (2011) 105(1):4-13. doi:10.1016/j.physbeh.2011.02.010
-
(2011)
Physiol Behav
, vol.105
, Issue.1
, pp. 4-13
-
-
Behrens, M.1
Meyerhof, W.2
-
27
-
-
55849136194
-
SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice
-
Jeon TI, Zhu B, Larson JL, Osborne TF. SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice. J Clin Invest (2008) 118(11):3693-700. doi:10.1172/JCI36461
-
(2008)
J Clin Invest
, vol.118
, Issue.11
, pp. 3693-3700
-
-
Jeon, T.I.1
Zhu, B.2
Larson, J.L.3
Osborne, T.F.4
-
28
-
-
84455160918
-
Effects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans
-
Wu T, Zhao BR, Bound MJ, Checklin HL, Bellon M, Little TJ, et al. Effects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans. Am J Clin Nutr (2012) 95(1):78-83. doi:10.3945/ajcn.111.021543
-
(2012)
Am J Clin Nutr
, vol.95
, Issue.1
, pp. 78-83
-
-
Wu, T.1
Zhao, B.R.2
Bound, M.J.3
Checklin, H.L.4
Bellon, M.5
Little, T.J.6
-
29
-
-
79953773104
-
Effects of oral ingestion of sucralose on gut hormone response and appetite in healthy normal-weight subjects
-
Ford HE, Peters V, Martin NM, Sleeth ML, Ghatei MA, Frost GS, et al. Effects of oral ingestion of sucralose on gut hormone response and appetite in healthy normal-weight subjects. Eur J Clin Nutr (2011) 65(4):508-13. doi:10.1038/ejcn.2010.291
-
(2011)
Eur J Clin Nutr
, vol.65
, Issue.4
, pp. 508-513
-
-
Ford, H.E.1
Peters, V.2
Martin, N.M.3
Sleeth, M.L.4
Ghatei, M.A.5
Frost, G.S.6
-
30
-
-
79955997980
-
Effects of carbohydrate sugars and artificial sweeteners on appetite and the secretion of gastrointestinal satiety peptides
-
Steinert RE, Frey F, Töpfer A, Drewe J, Beglinger C. Effects of carbohydrate sugars and artificial sweeteners on appetite and the secretion of gastrointestinal satiety peptides. Br J Nutr (2011) 105(9):1320-8. doi:10.1017/S000711451000512X
-
(2011)
Br J Nutr
, vol.105
, Issue.9
, pp. 1320-1328
-
-
Steinert, R.E.1
Frey, F.2
Töpfer, A.3
Drewe, J.4
Beglinger, C.5
-
31
-
-
84907197891
-
Diet-induced regulation of bitter taste receptor subtypes in the mouse gastrointestinal tract
-
Vegezzi G, Anselmi L, Huynh J, Barocelli E, Rozengurt E, Raybould H, et al. Diet-induced regulation of bitter taste receptor subtypes in the mouse gastrointestinal tract. PLoS One (2014) 9(9):e107732. doi:10.1371/journal.pone.0107732
-
(2014)
PLoS One
, vol.9
, Issue.9
-
-
Vegezzi, G.1
Anselmi, L.2
Huynh, J.3
Barocelli, E.4
Rozengurt, E.5
Raybould, H.6
-
32
-
-
84959449511
-
Expression of the bitter taste receptor, T2R38, in enteroendocrine cells of the colonic mucosa of overweight/obese vs. lean subjects
-
Latorre R, Huynh J, Mazzoni M, Gupta A, Bonora E, Clavenzani P, et al. Expression of the bitter taste receptor, T2R38, in enteroendocrine cells of the colonic mucosa of overweight/obese vs. lean subjects. PLoS One (2016) 11(2):e0147468. doi:10.1371/journal.pone.0147468
-
(2016)
PLoS One
, vol.11
, Issue.2
-
-
Latorre, R.1
Huynh, J.2
Mazzoni, M.3
Gupta, A.4
Bonora, E.5
Clavenzani, P.6
-
33
-
-
84920647529
-
Taste receptors in innate immunity
-
Lee RJ, Cohen NA. Taste receptors in innate immunity. Cell Mol Life Sci (2015) 72(2):217-36. doi:10.1007/s00018-014-1736-7
-
(2015)
Cell Mol Life Sci
, vol.72
, Issue.2
, pp. 217-236
-
-
Lee, R.J.1
Cohen, N.A.2
-
34
-
-
84893055427
-
Lipopolysaccharides-mediated increase in glucose-stimulated insulin secretion: involvement of the GLP-1 pathway
-
Nguyen AT, Mandard S, Dray C, Deckert V, Valet P, Besnard P, et al. Lipopolysaccharides-mediated increase in glucose-stimulated insulin secretion: involvement of the GLP-1 pathway. Diabetes (2014) 63(2):471-82. doi:10.2337/db13-0903
-
(2014)
Diabetes
, vol.63
, Issue.2
, pp. 471-482
-
-
Nguyen, A.T.1
Mandard, S.2
Dray, C.3
Deckert, V.4
Valet, P.5
Besnard, P.6
-
35
-
-
84887889962
-
Microbial modulation of energy availability in the colon regulates intestinal transit
-
Wichmann A, Allahyar A, Greiner TU, Plovier H, Lundén Gö, Larsson T, et al. Microbial modulation of energy availability in the colon regulates intestinal transit. Cell Host Microbe (2013) 14(5):582-90. doi:10.1016/j.chom.2013.09.012
-
(2013)
Cell Host Microbe
, vol.14
, Issue.5
, pp. 582-590
-
-
Wichmann, A.1
Allahyar, A.2
Greiner, T.U.3
Plovier, H.4
Lundén, Gö.5
Larsson, T.6
-
36
-
-
84912137874
-
Bacterial metabolite indole modulates incretin secretion from intestinal enteroendocrine L cells
-
Chimerel C, Emery E, Summers DK, Keyser U, Gribble FM, Reimann F. Bacterial metabolite indole modulates incretin secretion from intestinal enteroendocrine L cells. Cell Rep (2014) 9(4):1202-8. doi:10.1016/j.celrep.2014.10.032
-
(2014)
Cell Rep
, vol.9
, Issue.4
, pp. 1202-1208
-
-
Chimerel, C.1
Emery, E.2
Summers, D.K.3
Keyser, U.4
Gribble, F.M.5
Reimann, F.6
-
37
-
-
84880907693
-
The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic, inflammatory and neoplastic disorders
-
Stepanov V, Stankov K, Mikov M. The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic, inflammatory and neoplastic disorders. J Recept Signal Transduct Res (2013) 33(4):213-23. doi:10.3109/10799893.2013.802805
-
(2013)
J Recept Signal Transduct Res
, vol.33
, Issue.4
, pp. 213-223
-
-
Stepanov, V.1
Stankov, K.2
Mikov, M.3
-
38
-
-
33947667036
-
Activation of enteroendocrine cells via TLRs induces hormone, chemokine, and defensin secretion
-
Palazzo M, Balsari A, Rossini A, Selleri S, Calcaterra C, Gariboldi S, et al. Activation of enteroendocrine cells via TLRs induces hormone, chemokine, and defensin secretion. J Immunol (2007) 178(7):4296-303. doi:10.4049/jimmunol.178.7.4296
-
(2007)
J Immunol
, vol.178
, Issue.7
, pp. 4296-4303
-
-
Palazzo, M.1
Balsari, A.2
Rossini, A.3
Selleri, S.4
Calcaterra, C.5
Gariboldi, S.6
-
39
-
-
48249099626
-
Induction of pro-inflammatory programs in enteroendocrine cells by the Toll-like receptor agonists flagellin and bacterial LPS
-
Selleri S, Palazzo M, Deola S, Wang E, Balsari A, Marincola FM, et al. Induction of pro-inflammatory programs in enteroendocrine cells by the Toll-like receptor agonists flagellin and bacterial LPS. Int Immunol (2008) 20(8):961-70. doi:10.1093/intimm/dxn055
-
(2008)
Int Immunol
, vol.20
, Issue.8
, pp. 961-970
-
-
Selleri, S.1
Palazzo, M.2
Deola, S.3
Wang, E.4
Balsari, A.5
Marincola, F.M.6
-
40
-
-
34447505100
-
Enteroendocrine cells express functional Toll-like receptors
-
Bogunovic M, Davé SH, Tilstra JS, Chang DT, Harpaz N, Xiong H, et al. Enteroendocrine cells express functional Toll-like receptors. Am J Physiol Gastrointest Liver Physiol (2007) 292(6):G1770-83. doi:10.1152/ajpgi.00249.2006
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.292
, Issue.6
, pp. G1770-G1783
-
-
Bogunovic, M.1
Davé, S.H.2
Tilstra, J.S.3
Chang, D.T.4
Harpaz, N.5
Xiong, H.6
-
41
-
-
84868089442
-
Cellular bases for interactions between immunocytes and enteroendocrine cells in the intestinal mucosal barrier of rhesus macaques
-
Zhang WJ, Duan JZ, Lei N, Xing H, Shao Y, Yang GB. Cellular bases for interactions between immunocytes and enteroendocrine cells in the intestinal mucosal barrier of rhesus macaques. Cell Tissue Res (2012) 350(1):135-41. doi:10.1007/s00441-012-1464-y
-
(2012)
Cell Tissue Res
, vol.350
, Issue.1
, pp. 135-141
-
-
Zhang, W.J.1
Duan, J.Z.2
Lei, N.3
Xing, H.4
Shao, Y.5
Yang, G.B.6
-
42
-
-
84993690302
-
Enteroendocrine cells: neglected players in gastrointestinal disorders?
-
Moran GW, Leslie FC, Levison SE, Worthington J, McLaughlin JT. Enteroendocrine cells: neglected players in gastrointestinal disorders? Ther Adv Gastroenterol (2008) 1(1):51-60. doi:10.1177/1756283X08093943
-
(2008)
Ther Adv Gastroenterol
, vol.1
, Issue.1
, pp. 51-60
-
-
Moran, G.W.1
Leslie, F.C.2
Levison, S.E.3
Worthington, J.4
McLaughlin, J.T.5
-
43
-
-
84857349948
-
The role and pathophysiological relevance of membrane transporter PepT1 in intestinal inflammation and inflammatory bowel disease
-
Ingersoll SA, Ayyadurai S, Charania MA, Laroui H, Yan Y, Merlin D. The role and pathophysiological relevance of membrane transporter PepT1 in intestinal inflammation and inflammatory bowel disease. Am J Physiol Gastrointest Liver Physiol (2012) 302(5):G484-92. doi:10.1152/ajpgi.00477.2011
-
(2012)
Am J Physiol Gastrointest Liver Physiol
, vol.302
, Issue.5
, pp. G484-G492
-
-
Ingersoll, S.A.1
Ayyadurai, S.2
Charania, M.A.3
Laroui, H.4
Yan, Y.5
Merlin, D.6
-
44
-
-
64649096522
-
Targeted disruption of peptide transporter Pept1 gene in mice significantly reduces dipeptide absorption in intestine
-
Hu Y, Smith DE, Ma K, Jappar D, Thomas W, Hillgren KM. Targeted disruption of peptide transporter Pept1 gene in mice significantly reduces dipeptide absorption in intestine. Mol Pharm (2008) 5(6):1122-30. doi:10.1021/mp8001655
-
(2008)
Mol Pharm
, vol.5
, Issue.6
, pp. 1122-1130
-
-
Hu, Y.1
Smith, D.E.2
Ma, K.3
Jappar, D.4
Thomas, W.5
Hillgren, K.M.6
-
45
-
-
84898759705
-
Colonic expression of the peptide transporter PEPT1 is downregulated during intestinal inflammation and is not required for NOD2-dependent immune activation
-
Wuensch T, Ullrich S, Schulz S, Chamaillard M, Schaltenberg N, Rath E, et al. Colonic expression of the peptide transporter PEPT1 is downregulated during intestinal inflammation and is not required for NOD2-dependent immune activation. Inflamm Bowel Dis (2014) 20(4):671-84. doi:10.1097/01.MIB.0000443336.71488.08
-
(2014)
Inflamm Bowel Dis
, vol.20
, Issue.4
, pp. 671-684
-
-
Wuensch, T.1
Ullrich, S.2
Schulz, S.3
Chamaillard, M.4
Schaltenberg, N.5
Rath, E.6
-
46
-
-
80053616405
-
The PepT1-NOD2 signaling pathway aggravates induced colitis in mice
-
Dalmasso G, Nguyen HT, Ingersoll SA, Ayyadurai S, Laroui H, Charania MA, et al. The PepT1-NOD2 signaling pathway aggravates induced colitis in mice. Gastroenterology (2011) 141(4):1334-45. doi:10.1053/j.gastro.2011.06.080
-
(2011)
Gastroenterology
, vol.141
, Issue.4
, pp. 1334-1345
-
-
Dalmasso, G.1
Nguyen, H.T.2
Ingersoll, S.A.3
Ayyadurai, S.4
Laroui, H.5
Charania, M.A.6
-
47
-
-
81255157471
-
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
-
Ellingsgaard H, Hauselmann I, Schuler B, Habib AM, Baggio LL, Meier DT, et al. Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat Med (2011) 17(11):1481-9. doi:10.1038/nm.2513
-
(2011)
Nat Med
, vol.17
, Issue.11
, pp. 1481-1489
-
-
Ellingsgaard, H.1
Hauselmann, I.2
Schuler, B.3
Habib, A.M.4
Baggio, L.L.5
Meier, D.T.6
-
48
-
-
59649088932
-
Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell
-
Lim GE, Huang GJ, Flora N, LeRoith D, Rhodes CJ, Brubaker PL. Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell. Endocrinology (2009) 150(2):580-91. doi:10.1210/en.2008-0726
-
(2009)
Endocrinology
, vol.150
, Issue.2
, pp. 580-591
-
-
Lim, G.E.1
Huang, G.J.2
Flora, N.3
LeRoith, D.4
Rhodes, C.J.5
Brubaker, P.L.6
-
49
-
-
0030013475
-
Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor
-
Bullock BP, Heller RS, Habener JF. Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor. Endocrinology (1996) 137(7):2968-78. doi:10.1210/endo.137.7.8770921
-
(1996)
Endocrinology
, vol.137
, Issue.7
, pp. 2968-2978
-
-
Bullock, B.P.1
Heller, R.S.2
Habener, J.F.3
-
50
-
-
84962086818
-
GLP-1R agonists modulate enteric immune responses through the intestinal intraepithelial lymphocyte GLP-1R
-
Yusta B, Baggio LL, Koehler J, Holland D, Cao X, Pinnell LJ, et al. GLP-1R agonists modulate enteric immune responses through the intestinal intraepithelial lymphocyte GLP-1R. Diabetes (2015) 64(7):2537-49. doi:10.2337/db14-1577
-
(2015)
Diabetes
, vol.64
, Issue.7
, pp. 2537-2549
-
-
Yusta, B.1
Baggio, L.L.2
Koehler, J.3
Holland, D.4
Cao, X.5
Pinnell, L.J.6
-
51
-
-
26844436564
-
Nutritional stimulation of cholecystokinin receptors inhibits inflammation via the vagus nerve
-
Luyer MD, Greve JW, Hadfoune M, Jacobs JA, Dejong CH, Buurman WA. Nutritional stimulation of cholecystokinin receptors inhibits inflammation via the vagus nerve. J Exp Med (2005) 202(8):1023-9. doi:10.1084/jem.20042397
-
(2005)
J Exp Med
, vol.202
, Issue.8
, pp. 1023-1029
-
-
Luyer, M.D.1
Greve, J.W.2
Hadfoune, M.3
Jacobs, J.A.4
Dejong, C.H.5
Buurman, W.A.6
-
52
-
-
0034668106
-
Altered enteroendocrine cell expression in T cell receptor alpha chain knock-out mice
-
Rubin DC, Zhang H, Qian P, Lorenz RG, Hutton K, Peters MG. Altered enteroendocrine cell expression in T cell receptor alpha chain knock-out mice. Microsc Res Tech (2000) 51(2):112-20. doi:10.1002/1097-0029(20001015)51:2<112::AID-JEMT2>3.0.CO;2-D
-
(2000)
Microsc Res Tech
, vol.51
, Issue.2
, pp. 112-120
-
-
Rubin, D.C.1
Zhang, H.2
Qian, P.3
Lorenz, R.G.4
Hutton, K.5
Peters, M.G.6
-
53
-
-
33644864860
-
Consequences of Citrobacter rodentium infection on enteroendocrine cells and the enteric nervous system in the mouse colon
-
O'Hara JR, Skinn AC, MacNaughton WK, Sherman PM, Sharkey KA. Consequences of Citrobacter rodentium infection on enteroendocrine cells and the enteric nervous system in the mouse colon. Cell Microbiol (2006) 8(4):646-60. doi:10.1111/j.1462-5822.2005.00657.x
-
(2006)
Cell Microbiol
, vol.8
, Issue.4
, pp. 646-660
-
-
O'Hara, J.R.1
Skinn, A.C.2
MacNaughton, W.K.3
Sherman, P.M.4
Sharkey, K.A.5
-
54
-
-
77949268923
-
Glucagon-like peptide-1 receptor signalling selectively regulates murine lymphocyte proliferation and maintenance of peripheral regulatory T cells
-
Hadjiyanni I, Siminovitch KA, Danska JS, Drucker DJ. Glucagon-like peptide-1 receptor signalling selectively regulates murine lymphocyte proliferation and maintenance of peripheral regulatory T cells. Diabetologia (2010) 53(4):730-40. doi:10.1007/s00125-009-1643-x
-
(2010)
Diabetologia
, vol.53
, Issue.4
, pp. 730-740
-
-
Hadjiyanni, I.1
Siminovitch, K.A.2
Danska, J.S.3
Drucker, D.J.4
-
55
-
-
0027201145
-
Direct association of adenosine deaminase with a T cell activation antigen, CD26
-
Kameoka J, Tanaka T, Nojima Y, Schlossman SF, Morimoto C. Direct association of adenosine deaminase with a T cell activation antigen, CD26. Science (1993) 261(5120):466-9. doi:10.1126/science.8101391
-
(1993)
Science
, vol.261
, Issue.5120
, pp. 466-469
-
-
Kameoka, J.1
Tanaka, T.2
Nojima, Y.3
Schlossman, S.F.4
Morimoto, C.5
-
56
-
-
0031908130
-
The structure and function of CD26 in the T-cell immune response
-
Morimoto C, Schlossman SF. The structure and function of CD26 in the T-cell immune response. Immunol Rev (1998) 161:55-70. doi:10.1111/j.1600-065X.1998.tb01571.x
-
(1998)
Immunol Rev
, vol.161
, pp. 55-70
-
-
Morimoto, C.1
Schlossman, S.F.2
-
57
-
-
84892721397
-
Insulin inhibits IL-10-mediated regulatory T cell function: implications for obesity
-
Han JM, Patterson SJ, Speck M, Ehses JA, Levings MK. Insulin inhibits IL-10-mediated regulatory T cell function: implications for obesity. J Immunol (2014) 192(2):623-9. doi:10.4049/jimmunol.1302181
-
(2014)
J Immunol
, vol.192
, Issue.2
, pp. 623-629
-
-
Han, J.M.1
Patterson, S.J.2
Speck, M.3
Ehses, J.A.4
Levings, M.K.5
-
58
-
-
77952028081
-
Elevated circulating levels of an incretin hormone, glucagon-like peptide-1, are associated with metabolic components in high-risk patients with cardiovascular disease
-
Yamaoka-Tojo M, Tojo T, Takahira N, Matsunaga A, Aoyama N, Masuda T, et al. Elevated circulating levels of an incretin hormone, glucagon-like peptide-1, are associated with metabolic components in high-risk patients with cardiovascular disease. Cardiovasc Diabetol (2010) 9:17. doi:10.1186/1475-2840-9-17
-
(2010)
Cardiovasc Diabetol
, vol.9
, pp. 17
-
-
Yamaoka-Tojo, M.1
Tojo, T.2
Takahira, N.3
Matsunaga, A.4
Aoyama, N.5
Masuda, T.6
-
59
-
-
84881527658
-
Circulating concentrations of GLP-1 are associated with coronary atherosclerosis in humans
-
Piotrowski K, Becker M, Zugwurst J, Biller-Friedmann I, Spoettl G, Greif M, et al. Circulating concentrations of GLP-1 are associated with coronary atherosclerosis in humans. Cardiovasc Diabetol (2013) 12:117. doi:10.1186/1475-2840-12-117
-
(2013)
Cardiovasc Diabetol
, vol.12
, pp. 117
-
-
Piotrowski, K.1
Becker, M.2
Zugwurst, J.3
Biller-Friedmann, I.4
Spoettl, G.5
Greif, M.6
-
60
-
-
84885367670
-
Elevated plasma GLP-1 levels and enhanced expression of cardiac GLP-1 receptors as markers of left ventricular systolic dysfunction: a cross-sectional study
-
Hattori A, Kawamura I, Yamada Y, Kanamori H, Aoyama T, Ushikoshi H, et al. Elevated plasma GLP-1 levels and enhanced expression of cardiac GLP-1 receptors as markers of left ventricular systolic dysfunction: a cross-sectional study. BMJ Open (2013) 3(9):e003201. doi:10.1136/bmjopen-2013-003201
-
(2013)
BMJ Open
, vol.3
, Issue.9
-
-
Hattori, A.1
Kawamura, I.2
Yamada, Y.3
Kanamori, H.4
Aoyama, T.5
Ushikoshi, H.6
-
61
-
-
84907481915
-
GLP-1 secretion is increased by inflammatory stimuli in an IL-6-dependent manner, leading to hyperinsulinemia and blood glucose lowering
-
Kahles F, Meyer C, Möllmann J, Diebold S, Findeisen HM, Lebherz C, et al. GLP-1 secretion is increased by inflammatory stimuli in an IL-6-dependent manner, leading to hyperinsulinemia and blood glucose lowering. Diabetes (2014) 63(10):3221-9. doi:10.2337/db14-0100
-
(2014)
Diabetes
, vol.63
, Issue.10
, pp. 3221-3229
-
-
Kahles, F.1
Meyer, C.2
Möllmann, J.3
Diebold, S.4
Findeisen, H.M.5
Lebherz, C.6
-
62
-
-
75549091061
-
Incretin-based therapies: viewpoints on the way to consensus
-
Nauck MA, Vilsbøll T, Gallwitz B, Garber A, Madsbad S. Incretin-based therapies: viewpoints on the way to consensus. Diabetes Care (2009) 32(Suppl 2):S223-31. doi:10.2337/dc09-S315
-
(2009)
Diabetes Care
, vol.32
, pp. S223-S231
-
-
Nauck, M.A.1
Vilsbøll, T.2
Gallwitz, B.3
Garber, A.4
Madsbad, S.5
-
63
-
-
84946035690
-
Incretin-based drugs and adverse pancreatic events: almost a decade later and uncertainty remains
-
Azoulay L. Incretin-based drugs and adverse pancreatic events: almost a decade later and uncertainty remains. Diabetes Care (2015) 38(6):951-3. doi:10.2337/dc15-0347
-
(2015)
Diabetes Care
, vol.38
, Issue.6
, pp. 951-953
-
-
Azoulay, L.1
-
64
-
-
75149128665
-
Incretin-based therapies for the treatment of type 2 diabetes: evaluation of the risks and benefits
-
Drucker DJ, Sherman SI, Gorelick FS, Bergenstal RM, Sherwin RS, Buse JB. Incretin-based therapies for the treatment of type 2 diabetes: evaluation of the risks and benefits. Diabetes Care (2010) 33(2):428-33. doi:10.2337/dc09-1499
-
(2010)
Diabetes Care
, vol.33
, Issue.2
, pp. 428-433
-
-
Drucker, D.J.1
Sherman, S.I.2
Gorelick, F.S.3
Bergenstal, R.M.4
Sherwin, R.S.5
Buse, J.B.6
-
65
-
-
84896731936
-
Pancreatic safety of incretin-based drugs-FDA and EMA assessment
-
Egan AG, Blind E, Dunder K, de Graeff PA, Hummer BT, Bourcier T, et al. Pancreatic safety of incretin-based drugs-FDA and EMA assessment. N Engl J Med (2014) 370(9):794-7. doi:10.1056/NEJMp1314078
-
(2014)
N Engl J Med
, vol.370
, Issue.9
, pp. 794-797
-
-
Egan, A.G.1
Blind, E.2
Dunder, K.3
de Graeff, P.A.4
Hummer, B.T.5
Bourcier, T.6
-
66
-
-
84923123208
-
Blood pressure-lowering effects of incretin-based diabetes therapies
-
Lovshin JA, Zinman B. Blood pressure-lowering effects of incretin-based diabetes therapies. Can J Diabetes (2014) 38(5):364-71. doi:10.1016/j.jcjd.2014.05.001
-
(2014)
Can J Diabetes
, vol.38
, Issue.5
, pp. 364-371
-
-
Lovshin, J.A.1
Zinman, B.2
-
67
-
-
84901341959
-
Glucagon-like peptide-1 (GLP-1) analog liraglutide inhibits endothelial cell inflammation through a calcium and AMPK dependent mechanism
-
Krasner NM, Ido Y, Ruderman NB, Cacicedo JM. Glucagon-like peptide-1 (GLP-1) analog liraglutide inhibits endothelial cell inflammation through a calcium and AMPK dependent mechanism. PLoS One (2014) 9(5):e97554. doi:10.1371/journal.pone.0097554
-
(2014)
PLoS One
, vol.9
, Issue.5
-
-
Krasner, N.M.1
Ido, Y.2
Ruderman, N.B.3
Cacicedo, J.M.4
-
68
-
-
84924413179
-
Sitagliptin attenuates transient cerebral ischemia/reperfusion injury in diabetic rats: implication of the oxidative-inflammatory-apoptotic pathway
-
El-Sahar AE, Safar MM, Zaki HF, Attia AS, Ain-Shoka AA. Sitagliptin attenuates transient cerebral ischemia/reperfusion injury in diabetic rats: implication of the oxidative-inflammatory-apoptotic pathway. Life Sci (2015) 126:81-6. doi:10.1016/j.lfs.2015.01.030
-
(2015)
Life Sci
, vol.126
, pp. 81-86
-
-
El-Sahar, A.E.1
Safar, M.M.2
Zaki, H.F.3
Attia, A.S.4
Ain-Shoka, A.A.5
-
69
-
-
80053001967
-
GLP-1 analogs reduce hepatocyte steatosis and improve survival by enhancing the unfolded protein response and promoting macroautophagy
-
Sharma S, Mells JE, Fu PP, Saxena NK, Anania FA. GLP-1 analogs reduce hepatocyte steatosis and improve survival by enhancing the unfolded protein response and promoting macroautophagy. PLoS One (2011) 6(9):e25269. doi:10.1371/journal.pone.0025269
-
(2011)
PLoS One
, vol.6
, Issue.9
-
-
Sharma, S.1
Mells, J.E.2
Fu, P.P.3
Saxena, N.K.4
Anania, F.A.5
-
70
-
-
84910603708
-
Effects of glucagon-like peptide-1 receptor agonists on non-alcoholic fatty liver disease and inflammation
-
Wang XC, Gusdon AM, Liu H, Qu S. Effects of glucagon-like peptide-1 receptor agonists on non-alcoholic fatty liver disease and inflammation. World J Gastroenterol (2014) 20(40):14821-30. doi:10.3748/wjg.v20.i40.14821
-
(2014)
World J Gastroenterol
, vol.20
, Issue.40
, pp. 14821-14830
-
-
Wang, X.C.1
Gusdon, A.M.2
Liu, H.3
Qu, S.4
-
71
-
-
84927740133
-
Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury
-
Higashijima Y, Tanaka T, Yamaguchi J, Tanaka S, Nangaku M. Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury. Am J Physiol Renal Physiol (2015) 308(8):F878-87. doi:10.1152/ajprenal.00590.2014
-
(2015)
Am J Physiol Renal Physiol
, vol.308
, Issue.8
, pp. F878-F887
-
-
Higashijima, Y.1
Tanaka, T.2
Yamaguchi, J.3
Tanaka, S.4
Nangaku, M.5
-
72
-
-
84897829368
-
The incretin hormones glucagonlike peptide 1 and glucose-dependent insulinotropic polypeptide are neuroprotective in mouse models of Alzheimer's disease
-
Holscher C. The incretin hormones glucagonlike peptide 1 and glucose-dependent insulinotropic polypeptide are neuroprotective in mouse models of Alzheimer's disease. Alzheimers Dement (2014) 10(1 Suppl):S47-54. doi:10.1016/j.jalz.2013.12.009
-
(2014)
Alzheimers Dement
, vol.10
, Issue.1
, pp. S47-S54
-
-
Holscher, C.1
-
73
-
-
84895067918
-
Glucagon-like peptide-1 protects synaptic and learning functions from neuroinflammation in rodents
-
Iwai T, Sawabe T, Tanimitsu K, Suzuki M, Sasaki-Hamada S, Oka J. Glucagon-like peptide-1 protects synaptic and learning functions from neuroinflammation in rodents. J Neurosci Res (2014) 92(4):446-54. doi:10.1002/jnr.23335
-
(2014)
J Neurosci Res
, vol.92
, Issue.4
, pp. 446-454
-
-
Iwai, T.1
Sawabe, T.2
Tanimitsu, K.3
Suzuki, M.4
Sasaki-Hamada, S.5
Oka, J.6
-
74
-
-
84892516423
-
From endocrine to rheumatism: do gut hormones play roles in rheumatoid arthritis?
-
Chen CY, Tsai CY. From endocrine to rheumatism: do gut hormones play roles in rheumatoid arthritis? Rheumatology (Oxford) (2014) 53(2):205-12. doi:10.1093/rheumatology/ket255
-
(2014)
Rheumatology (Oxford)
, vol.53
, Issue.2
, pp. 205-212
-
-
Chen, C.Y.1
Tsai, C.Y.2
-
75
-
-
84929306694
-
Glucagon like peptide-1 attenuates bleomycin-induced pulmonary fibrosis, involving the inactivation of NF-kappaB in mice
-
Gou S, Zhu T, Wang W, Xiao M, Wang XC, Chen ZH. Glucagon like peptide-1 attenuates bleomycin-induced pulmonary fibrosis, involving the inactivation of NF-kappaB in mice. Int Immunopharmacol (2014) 22(2):498-504. doi:10.1016/j.intimp.2014.07.010
-
(2014)
Int Immunopharmacol
, vol.22
, Issue.2
, pp. 498-504
-
-
Gou, S.1
Zhu, T.2
Wang, W.3
Xiao, M.4
Wang, X.C.5
Chen, Z.H.6
-
76
-
-
84878936553
-
Extra-pancreatic effects of incretin-based therapies: potential benefit for cardiovascular-risk management in type 2 diabetes
-
van Genugten RE, Möller-Goede DL, van Raalte DH, Diamant M. Extra-pancreatic effects of incretin-based therapies: potential benefit for cardiovascular-risk management in type 2 diabetes. Diabetes Obes Metab (2013) 15(7):593-606. doi:10.1111/dom.12050
-
(2013)
Diabetes Obes Metab
, vol.15
, Issue.7
, pp. 593-606
-
-
van Genugten, R.E.1
Möller-Goede, D.L.2
van Raalte, D.H.3
Diamant, M.4
-
77
-
-
84858707110
-
The glucagon-like peptide 1 analog liraglutide reduces TNF-alpha-induced oxidative stress and inflammation in endothelial cells
-
Shiraki A, Oyama J, Komoda H, Asaka M, Komatsu A, Sakuma M, et al. The glucagon-like peptide 1 analog liraglutide reduces TNF-alpha-induced oxidative stress and inflammation in endothelial cells. Atherosclerosis (2012) 221(2):375-82. doi:10.1016/j.atherosclerosis.2011.12.039
-
(2012)
Atherosclerosis
, vol.221
, Issue.2
, pp. 375-382
-
-
Shiraki, A.1
Oyama, J.2
Komoda, H.3
Asaka, M.4
Komatsu, A.5
Sakuma, M.6
-
78
-
-
84880147886
-
Anti-inflammatory effects of exendin-4, a glucagon-like peptide-1 analog, on human peripheral lymphocytes in patients with type 2 diabetes
-
He L, Wong CK, Cheung KK, Yau HC, Fu A, Zhao HL, et al. Anti-inflammatory effects of exendin-4, a glucagon-like peptide-1 analog, on human peripheral lymphocytes in patients with type 2 diabetes. J Diabetes Investig (2013) 4(4):382-92. doi:10.1111/jdi.12063
-
(2013)
J Diabetes Investig
, vol.4
, Issue.4
, pp. 382-392
-
-
He, L.1
Wong, C.K.2
Cheung, K.K.3
Yau, H.C.4
Fu, A.5
Zhao, H.L.6
-
79
-
-
84866055251
-
Glucagon-like peptide-1 inhibits adipose tissue macrophage infiltration and inflammation in an obese mouse model of diabetes
-
Lee YS, Park MS, Choung JS, Kim SS, Oh HH, Choi CS, et al. Glucagon-like peptide-1 inhibits adipose tissue macrophage infiltration and inflammation in an obese mouse model of diabetes. Diabetologia (2012) 55(9):2456-68. doi:10.1007/s00125-012-2592-3
-
(2012)
Diabetologia
, vol.55
, Issue.9
, pp. 2456-2468
-
-
Lee, Y.S.1
Park, M.S.2
Choung, J.S.3
Kim, S.S.4
Oh, H.H.5
Choi, C.S.6
-
80
-
-
84908632327
-
SIRT1 mediates the effect of GLP-1 receptor agonist exenatide on ameliorating hepatic steatosis
-
Xu F, Li Z, Zheng X, Liu H, Liang H, Xu H, et al. SIRT1 mediates the effect of GLP-1 receptor agonist exenatide on ameliorating hepatic steatosis. Diabetes (2014) 63(11):3637-46. doi:10.2337/db14-0263
-
(2014)
Diabetes
, vol.63
, Issue.11
, pp. 3637-3646
-
-
Xu, F.1
Li, Z.2
Zheng, X.3
Liu, H.4
Liang, H.5
Xu, H.6
-
81
-
-
34447103388
-
Increase in DPP-IV in the intestine, liver and kidney of the rat treated with high fat diet and streptozotocin
-
Yang J, Campitelli J, Hu G, Lin Y, Luo J, Xue C. Increase in DPP-IV in the intestine, liver and kidney of the rat treated with high fat diet and streptozotocin. Life Sci (2007) 81(4):272-9. doi:10.1016/j.lfs.2007.04.040
-
(2007)
Life Sci
, vol.81
, Issue.4
, pp. 272-279
-
-
Yang, J.1
Campitelli, J.2
Hu, G.3
Lin, Y.4
Luo, J.5
Xue, C.6
-
82
-
-
84878485447
-
CD26/DPP4 levels in peripheral blood and T cells in patients with type 2 diabetes mellitus
-
Lee SA, Kim YR, Yang EJ, Kwon EJ, Kim SH, Kang SH, et al. CD26/DPP4 levels in peripheral blood and T cells in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab (2013) 98(6):2553-61. doi:10.1210/jc.2012-4288
-
(2013)
J Clin Endocrinol Metab
, vol.98
, Issue.6
, pp. 2553-2561
-
-
Lee, S.A.1
Kim, Y.R.2
Yang, E.J.3
Kwon, E.J.4
Kim, S.H.5
Kang, S.H.6
-
83
-
-
70350328161
-
Dipeptidyl peptidase inhibitors, an emerging drug class for inflammatory disease?
-
Yazbeck R, Howarth GS, Abbott CA. Dipeptidyl peptidase inhibitors, an emerging drug class for inflammatory disease? Trends Pharmacol Sci (2009) 30(11):600-7. doi:10.1016/j.tips.2009.08.003
-
(2009)
Trends Pharmacol Sci
, vol.30
, Issue.11
, pp. 600-607
-
-
Yazbeck, R.1
Howarth, G.S.2
Abbott, C.A.3
-
84
-
-
0030744259
-
Inhibitors of dipeptidyl peptidase IV induce secretion of transforming growth factor-beta 1 in PWM-stimulated PBMC and T cells
-
Reinhold D, Bank U, Bühling F, Lendeckel U, Faust J, Neubert K, et al. Inhibitors of dipeptidyl peptidase IV induce secretion of transforming growth factor-beta 1 in PWM-stimulated PBMC and T cells. Immunology (1997) 91(3):354-60. doi:10.1046/j.1365-2567.1997.d01-2258.x
-
(1997)
Immunology
, vol.91
, Issue.3
, pp. 354-360
-
-
Reinhold, D.1
Bank, U.2
Bühling, F.3
Lendeckel, U.4
Faust, J.5
Neubert, K.6
-
85
-
-
84889654817
-
Dipeptidyl peptidase-4 inhibitors: multitarget drugs, not only antidiabetes drugs
-
Zhao Y, Yang L, Zhou Z. Dipeptidyl peptidase-4 inhibitors: multitarget drugs, not only antidiabetes drugs. J Diabetes (2014) 6(1):21-9. doi:10.1111/1753-0407.12063
-
(2014)
J Diabetes
, vol.6
, Issue.1
, pp. 21-29
-
-
Zhao, Y.1
Yang, L.2
Zhou, Z.3
-
86
-
-
65149091474
-
Genetic ablation or pharmacological blockade of dipeptidyl peptidase IV does not impact T cell-dependent immune responses
-
Vora KA, Porter G, Peng R, Cui Y, Pryor K, Eiermann G, et al. Genetic ablation or pharmacological blockade of dipeptidyl peptidase IV does not impact T cell-dependent immune responses. BMC Immunol (2009) 10:19. doi:10.1186/1471-2172-10-19
-
(2009)
BMC Immunol
, vol.10
, pp. 19
-
-
Vora, K.A.1
Porter, G.2
Peng, R.3
Cui, Y.4
Pryor, K.5
Eiermann, G.6
-
87
-
-
84886400216
-
Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance
-
Aroor AR, McKarns S, Demarco VG, Jia G, Sowers JR. Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance. Metabolism (2013) 62(11):1543-52. doi:10.1016/j.metabol.2013.07.001
-
(2013)
Metabolism
, vol.62
, Issue.11
, pp. 1543-1552
-
-
Aroor, A.R.1
McKarns, S.2
Demarco, V.G.3
Jia, G.4
Sowers, J.R.5
-
88
-
-
84919712450
-
DPP-4 inhibitors repress NLRP3 inflammasome and interleukin-1beta via GLP-1 receptor in macrophages through protein kinase C pathway
-
Dai Y, Dai D, Wang X, Ding Z, Mehta JL. DPP-4 inhibitors repress NLRP3 inflammasome and interleukin-1beta via GLP-1 receptor in macrophages through protein kinase C pathway. Cardiovasc Drugs Ther (2014) 28(5):425-32. doi:10.1007/s10557-014-6539-4
-
(2014)
Cardiovasc Drugs Ther
, vol.28
, Issue.5
, pp. 425-432
-
-
Dai, Y.1
Dai, D.2
Wang, X.3
Ding, Z.4
Mehta, J.L.5
-
89
-
-
84903487864
-
Dipeptidyl peptidase-IV inhibition prevents blood-retinal barrier breakdown, inflammation and neuronal cell death in the retina of type 1 diabetic rats
-
Gonçalves A, Marques C, Leal E, Ribeiro CF, Reis F, Ambrósio AF, et al. Dipeptidyl peptidase-IV inhibition prevents blood-retinal barrier breakdown, inflammation and neuronal cell death in the retina of type 1 diabetic rats. Biochim Biophys Acta (2014) 1842(9):1454-63. doi:10.1016/j.bbadis.2014.04.013
-
(2014)
Biochim Biophys Acta
, vol.1842
, Issue.9
, pp. 1454-1463
-
-
Gonçalves, A.1
Marques, C.2
Leal, E.3
Ribeiro, C.F.4
Reis, F.5
Ambrósio, A.F.6
-
90
-
-
33846453555
-
Relationship of serum interleukin-6 and tumor necrosis factor alpha levels with abdominal fat distribution evaluated by ultrasonography in overweight or obese postmenopausal women
-
Fenkci S, Rota S, Sabir N, Sermez Y, Guclu A, Akdag B. Relationship of serum interleukin-6 and tumor necrosis factor alpha levels with abdominal fat distribution evaluated by ultrasonography in overweight or obese postmenopausal women. J Investig Med (2006) 54(8):455-60. doi:10.2310/6650.2006.06010
-
(2006)
J Investig Med
, vol.54
, Issue.8
, pp. 455-460
-
-
Fenkci, S.1
Rota, S.2
Sabir, N.3
Sermez, Y.4
Guclu, A.5
Akdag, B.6
-
91
-
-
78049419440
-
A meta-analysis of cytokines in Alzheimer's disease
-
Swardfager W, Lanctôt K, Rothenburg L, Wong A, Cappell J, Herrmann N. A meta-analysis of cytokines in Alzheimer's disease. Biol Psychiatry (2010) 68(10):930-41. doi:10.1016/j.biopsych.2010.06.012
-
(2010)
Biol Psychiatry
, vol.68
, Issue.10
, pp. 930-941
-
-
Swardfager, W.1
Lanctôt, K.2
Rothenburg, L.3
Wong, A.4
Cappell, J.5
Herrmann, N.6
-
92
-
-
0035936797
-
The TNF and TNF receptor superfamilies: integrating mammalian biology
-
Locksley RM, Killeen N, Lenardo MJ. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell (2001) 104(4):487-501. doi:10.1016/S0092-8674(01)00237-9
-
(2001)
Cell
, vol.104
, Issue.4
, pp. 487-501
-
-
Locksley, R.M.1
Killeen, N.2
Lenardo, M.J.3
-
93
-
-
0036288520
-
Tumour necrosis factor alpha converting enzyme (TACE) activity in the colonic mucosa of patients with inflammatory bowel disease
-
Brynskov J, Foegh P, Pedersen G, Ellervik C, Kirkegaard T, Bingham A, et al. Tumour necrosis factor alpha converting enzyme (TACE) activity in the colonic mucosa of patients with inflammatory bowel disease. Gut (2002) 51(1):37-43. doi:10.1136/gut.51.1.37
-
(2002)
Gut
, vol.51
, Issue.1
, pp. 37-43
-
-
Brynskov, J.1
Foegh, P.2
Pedersen, G.3
Ellervik, C.4
Kirkegaard, T.5
Bingham, A.6
-
94
-
-
0030756346
-
Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
-
Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS. Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature (1997) 389(6651):610-4. doi:10.1038/39335
-
(1997)
Nature
, vol.389
, Issue.6651
, pp. 610-614
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Marino, M.W.3
Hotamisligil, G.S.4
-
95
-
-
84946079534
-
Chronic exposure to TNFalpha impairs secretion of glucagon-like peptide-1
-
Gagnon J, Sauvé M, Zhao W, Stacey HM, Wiber SC, Bolz SS, et al. Chronic exposure to TNFalpha impairs secretion of glucagon-like peptide-1. Endocrinology (2015) 156(11):3950-60. doi:10.1210/en.2015-1361
-
(2015)
Endocrinology
, vol.156
, Issue.11
, pp. 3950-3960
-
-
Gagnon, J.1
Sauvé, M.2
Zhao, W.3
Stacey, H.M.4
Wiber, S.C.5
Bolz, S.S.6
-
96
-
-
84918779133
-
Tumor necrosis factor alpha decreases glucagon-like peptide-2 expression by up-regulating G-protein-coupled receptor 120 in Crohn disease
-
Tsukahara T, Watanabe K, Watanabe T, Yamagami H, Sogawa M, Tanigawa T, et al. Tumor necrosis factor alpha decreases glucagon-like peptide-2 expression by up-regulating G-protein-coupled receptor 120 in Crohn disease. Am J Pathol (2015) 185(1):185-96. doi:10.1016/j.ajpath.2014.09.010
-
(2015)
Am J Pathol
, vol.185
, Issue.1
, pp. 185-196
-
-
Tsukahara, T.1
Watanabe, K.2
Watanabe, T.3
Yamagami, H.4
Sogawa, M.5
Tanigawa, T.6
-
97
-
-
84927615412
-
The effects of TNF-alpha on GLP-1-stimulated plasma glucose kinetics
-
Lehrskov-Schmidt L, Lehrskov-Schmidt L, Nielsen ST, Holst JJ, Møller K, Solomon TP. The effects of TNF-alpha on GLP-1-stimulated plasma glucose kinetics. J Clin Endocrinol Metab (2015) 100(4):E616-22. doi:10.1210/jc.2014-4244
-
(2015)
J Clin Endocrinol Metab
, vol.100
, Issue.4
, pp. E616-E622
-
-
Lehrskov-Schmidt, L.1
Lehrskov-Schmidt, L.2
Nielsen, S.T.3
Holst, J.J.4
Møller, K.5
Solomon, T.P.6
-
98
-
-
62349142022
-
Effects of tumor necrosis factor alpha inhibition with infliximab on lipid levels and insulin resistance in patients with inflammatory bowel disease
-
Koutroubakis IE, Oustamanolakis P, Malliaraki N, Karmiris K, Chalkiadakis I, Ganotakis E, et al. Effects of tumor necrosis factor alpha inhibition with infliximab on lipid levels and insulin resistance in patients with inflammatory bowel disease. Eur J Gastroenterol Hepatol (2009) 21(3):283-8. doi:10.1097/MEG.0b013e328325d42b
-
(2009)
Eur J Gastroenterol Hepatol
, vol.21
, Issue.3
, pp. 283-288
-
-
Koutroubakis, I.E.1
Oustamanolakis, P.2
Malliaraki, N.3
Karmiris, K.4
Chalkiadakis, I.5
Ganotakis, E.6
-
99
-
-
84856827310
-
Endocrine and metabolic manifestations in inflammatory bowel disease
-
Tigas S, Tsatsoulis A. Endocrine and metabolic manifestations in inflammatory bowel disease. Ann Gastroenterol (2012) 25(1):37-44
-
(2012)
Ann Gastroenterol
, vol.25
, Issue.1
, pp. 37-44
-
-
Tigas, S.1
Tsatsoulis, A.2
-
100
-
-
57849149043
-
Carbohydrate and lipid metabolism following infliximab therapy in pediatric Crohn's disease
-
Steiner SJ, Pfefferkorn MD, Fitzgerald JF, Denne SC. Carbohydrate and lipid metabolism following infliximab therapy in pediatric Crohn's disease. Pediatr Res (2008) 64(6):673-6. doi:10.1203/PDR.0b013e318186dde2
-
(2008)
Pediatr Res
, vol.64
, Issue.6
, pp. 673-676
-
-
Steiner, S.J.1
Pfefferkorn, M.D.2
Fitzgerald, J.F.3
Denne, S.C.4
-
101
-
-
84876738647
-
Long-term etanercept therapy favors weight gain and ameliorates cachexia in rheumatoid arthritis patients: roles of gut hormones and leptin
-
Chen CY, Tsai CY, Lee PC, Lee SD. Long-term etanercept therapy favors weight gain and ameliorates cachexia in rheumatoid arthritis patients: roles of gut hormones and leptin. Curr Pharm Des (2013) 19(10):1956-64. doi:10.2174/1381612811319100014
-
(2013)
Curr Pharm Des
, vol.19
, Issue.10
, pp. 1956-1964
-
-
Chen, C.Y.1
Tsai, C.Y.2
Lee, P.C.3
Lee, S.D.4
-
102
-
-
84928568835
-
IL-6 as a keystone cytokine in health and disease
-
Hunter CA, Jones SA. IL-6 as a keystone cytokine in health and disease. Nat Immunol (2015) 16(5):448-57. doi:10.1038/ni.3153
-
(2015)
Nat Immunol
, vol.16
, Issue.5
, pp. 448-457
-
-
Hunter, C.A.1
Jones, S.A.2
-
103
-
-
79953680176
-
Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: results from the double-blind treatment phase of a randomized placebo-controlled trial of tocilizumab safety and prevention of structural joint damage at one year
-
Kremer JM, Blanco R, Brzosko M, Burgos-Vargas R, Halland AM, Vernon E, et al. Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: results from the double-blind treatment phase of a randomized placebo-controlled trial of tocilizumab safety and prevention of structural joint damage at one year. Arthritis Rheum (2011) 63(3):609-21. doi:10.1002/art.30158
-
(2011)
Arthritis Rheum
, vol.63
, Issue.3
, pp. 609-621
-
-
Kremer, J.M.1
Blanco, R.2
Brzosko, M.3
Burgos-Vargas, R.4
Halland, A.M.5
Vernon, E.6
-
104
-
-
84918522920
-
IL-6 stimulates intestinal epithelial proliferation and repair after injury
-
Kuhn KA, Manieri NA, Liu TC, Stappenbeck TS. IL-6 stimulates intestinal epithelial proliferation and repair after injury. PLoS One (2014) 9(12):e114195. doi:10.1371/journal.pone.0114195
-
(2014)
PLoS One
, vol.9
, Issue.12
-
-
Kuhn, K.A.1
Manieri, N.A.2
Liu, T.C.3
Stappenbeck, T.S.4
-
105
-
-
33644594409
-
Association of systemic chemokine concentrations with impaired glucose tolerance and type 2 diabetes: results from the Cooperative Health Research in the Region of Augsburg Survey S4 (KORA S4)
-
Herder C, Haastert B, Müller-Scholze S, Koenig W, Thorand B, Holle R, et al. Association of systemic chemokine concentrations with impaired glucose tolerance and type 2 diabetes: results from the Cooperative Health Research in the Region of Augsburg Survey S4 (KORA S4). Diabetes (2005) 54(Suppl 2):S11-7. doi:10.2337/diabetes.54.suppl_2.S11
-
(2005)
Diabetes
, vol.54
, pp. S11-S17
-
-
Herder, C.1
Haastert, B.2
Müller-Scholze, S.3
Koenig, W.4
Thorand, B.5
Holle, R.6
-
106
-
-
0030735542
-
Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo
-
Mohamed-Ali V, Goodrick S, Rawesh A, Katz DR, Miles JM, Yudkin JS, et al. Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo. J Clin Endocrinol Metab (1997) 82(12):4196-200. doi:10.1210/jcem.82.12.4450
-
(1997)
J Clin Endocrinol Metab
, vol.82
, Issue.12
, pp. 4196-4200
-
-
Mohamed-Ali, V.1
Goodrick, S.2
Rawesh, A.3
Katz, D.R.4
Miles, J.M.5
Yudkin, J.S.6
-
107
-
-
51349111709
-
Prolonged interleukin-6 administration enhances glucose tolerance and increases skeletal muscle PPARalpha and UCP2 expression in rats
-
Holmes AG, Mesa JL, Neill BA, Chung J, Carey AL, Steinberg GR, et al. Prolonged interleukin-6 administration enhances glucose tolerance and increases skeletal muscle PPARalpha and UCP2 expression in rats. J Endocrinol (2008) 198(2):367-74. doi:10.1677/JOE-08-0113
-
(2008)
J Endocrinol
, vol.198
, Issue.2
, pp. 367-374
-
-
Holmes, A.G.1
Mesa, J.L.2
Neill, B.A.3
Chung, J.4
Carey, A.L.5
Steinberg, G.R.6
-
108
-
-
33646350774
-
Direct cross-talk of interleukin-6 and insulin signal transduction via insulin receptor substrate-1 in skeletal muscle cells
-
Weigert C, Hennige AM, Lehmann R, Brodbeck K, Baumgartner F, Schaüble M, et al. Direct cross-talk of interleukin-6 and insulin signal transduction via insulin receptor substrate-1 in skeletal muscle cells. J Biol Chem (2006) 281(11):7060-7. doi:10.1074/jbc.M509782200
-
(2006)
J Biol Chem
, vol.281
, Issue.11
, pp. 7060-7067
-
-
Weigert, C.1
Hennige, A.M.2
Lehmann, R.3
Brodbeck, K.4
Baumgartner, F.5
Schaüble, M.6
-
109
-
-
84885031186
-
Glucagon-like peptide 1 receptor induced suppression of food intake, and body weight is mediated by central IL-1 and IL-6
-
Shirazi R, Palsdottir V, Collander J, Anesten F, Vogel H, Langlet F, et al. Glucagon-like peptide 1 receptor induced suppression of food intake, and body weight is mediated by central IL-1 and IL-6. Proc Natl Acad Sci U S A (2013) 110(40):16199-204. doi:10.1073/pnas.1306799110
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.40
, pp. 16199-16204
-
-
Shirazi, R.1
Palsdottir, V.2
Collander, J.3
Anesten, F.4
Vogel, H.5
Langlet, F.6
-
110
-
-
70350561703
-
Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle
-
Hong EG, Ko HJ, Cho YR, Kim HJ, Ma Z, Yu TY, et al. Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle. Diabetes (2009) 58(11):2525-35. doi:10.2337/db08-1261
-
(2009)
Diabetes
, vol.58
, Issue.11
, pp. 2525-2535
-
-
Hong, E.G.1
Ko, H.J.2
Cho, Y.R.3
Kim, H.J.4
Ma, Z.5
Yu, T.Y.6
-
111
-
-
84966710938
-
Role of adiponectin and some other factors linking type 2 diabetes mellitus and obesity
-
Chakraborti CK. Role of adiponectin and some other factors linking type 2 diabetes mellitus and obesity. World J Diabetes (2015) 6(15):1296-308. doi:10.4239/wjd.v6.i15.1296
-
(2015)
World J Diabetes
, vol.6
, Issue.15
, pp. 1296-1308
-
-
Chakraborti, C.K.1
-
112
-
-
84905284828
-
RANTES (CCL5) reduces glucose-dependent secretion of glucagon-like peptides 1 and 2 and impairs glucose-induced insulin secretion in mice
-
Pais R, Zietek T, Hauner H, Daniel H, Skurk T. RANTES (CCL5) reduces glucose-dependent secretion of glucagon-like peptides 1 and 2 and impairs glucose-induced insulin secretion in mice. Am J Physiol Gastrointest Liver Physiol (2014) 307(3):G330-7. doi:10.1152/ajpgi.00329.2013
-
(2014)
Am J Physiol Gastrointest Liver Physiol
, vol.307
, Issue.3
, pp. G330-G337
-
-
Pais, R.1
Zietek, T.2
Hauner, H.3
Daniel, H.4
Skurk, T.5
-
113
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol (2007) 8(7):519-29. doi:10.1038/nrm2199
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.7
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
114
-
-
22244446505
-
The mammalian unfolded protein response
-
Schroder M, Kaufman RJ. The mammalian unfolded protein response. Annu Rev Biochem (2005) 74:739-89. doi:10.1146/annurev.biochem.73.011303.074134
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 739-789
-
-
Schroder, M.1
Kaufman, R.J.2
-
115
-
-
33751069967
-
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins
-
Rutkowski DT, Arnold SM, Miller CN, Wu J, Li J, Gunnison KM, et al. Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins. PLoS Biol (2006) 4(11):e374. doi:10.1371/journal.pbio.0040374
-
(2006)
PLoS Biol
, vol.4
, Issue.11
-
-
Rutkowski, D.T.1
Arnold, S.M.2
Miller, C.N.3
Wu, J.4
Li, J.5
Gunnison, K.M.6
-
116
-
-
33748789479
-
Mediators of endoplasmic reticulum stress-induced apoptosis
-
Szegezdi E, Logue SE, Gorman AM, Samali A. Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep (2006) 7(9):880-5. doi:10.1038/sj.embor.7400779
-
(2006)
EMBO Rep
, vol.7
, Issue.9
, pp. 880-885
-
-
Szegezdi, E.1
Logue, S.E.2
Gorman, A.M.3
Samali, A.4
-
117
-
-
0035094262
-
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice
-
Bertolotti A, Wang X, Novoa I, Jungreis R, Schlessinger K, Cho JH, et al. Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice. J Clin Invest (2001) 107(5):585-93. doi:10.1172/JCI11476
-
(2001)
J Clin Invest
, vol.107
, Issue.5
, pp. 585-593
-
-
Bertolotti, A.1
Wang, X.2
Novoa, I.3
Jungreis, R.4
Schlessinger, K.5
Cho, J.H.6
-
118
-
-
41549092745
-
Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis
-
Heazlewood CK, Cook MC, Eri R, Price GR, Tauro SB, Taupin D, et al. Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis. PLoS Med (2008) 5(3):e54. doi:10.1371/journal.pmed.0050054
-
(2008)
PLoS Med
, vol.5
, Issue.3
-
-
Heazlewood, C.K.1
Cook, M.C.2
Eri, R.3
Price, G.R.4
Tauro, S.B.5
Taupin, D.6
-
119
-
-
50249086073
-
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
-
Kaser A, Lee AH, Franke A, Glickman JN, Zeissig S, Tilg H, et al. XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell (2008) 134(5):743-56. doi:10.1016/j.cell.2008.07.021
-
(2008)
Cell
, vol.134
, Issue.5
, pp. 743-756
-
-
Kaser, A.1
Lee, A.H.2
Franke, A.3
Glickman, J.N.4
Zeissig, S.5
Tilg, H.6
-
120
-
-
77951290227
-
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
-
Martinon F, Chen X, Lee AH, Glimcher LH. TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. Nat Immunol (2010) 11(5):411-8. doi:10.1038/ni.1857
-
(2010)
Nat Immunol
, vol.11
, Issue.5
, pp. 411-418
-
-
Martinon, F.1
Chen, X.2
Lee, A.H.3
Glimcher, L.H.4
-
121
-
-
8644282751
-
Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2
-
Deng J, Lu PD, Zhang Y, Scheuner D, Kaufman RJ, Sonenberg N, et al. Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2. Mol Cell Biol (2004) 24(23):10161-8. doi:10.1128/MCB.24.23.10161-10168.2004
-
(2004)
Mol Cell Biol
, vol.24
, Issue.23
, pp. 10161-10168
-
-
Deng, J.1
Lu, P.D.2
Zhang, Y.3
Scheuner, D.4
Kaufman, R.J.5
Sonenberg, N.6
-
122
-
-
1842843860
-
Coupling endoplasmic reticulum stress to the cell death program
-
Rao RV, Ellerby HM, Bredesen DE. Coupling endoplasmic reticulum stress to the cell death program. Cell Death Differ (2004) 11(4):372-80. doi:10.1038/sj.cdd.4401378
-
(2004)
Cell Death Differ
, vol.11
, Issue.4
, pp. 372-380
-
-
Rao, R.V.1
Ellerby, H.M.2
Bredesen, D.E.3
-
123
-
-
33645815074
-
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression
-
Hu P, Han Z, Couvillon AD, Kaufman RJ, Exton JH. Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression. Mol Cell Biol (2006) 26(8):3071-84. doi:10.1128/MCB.26.8.3071-3084.2006
-
(2006)
Mol Cell Biol
, vol.26
, Issue.8
, pp. 3071-3084
-
-
Hu, P.1
Han, Z.2
Couvillon, A.D.3
Kaufman, R.J.4
Exton, J.H.5
-
124
-
-
79953044109
-
Adenylate kinase 2 links mitochondrial energy metabolism to the induction of the unfolded protein response
-
Burkart A, Shi X, Chouinard M, Corvera S. Adenylate kinase 2 links mitochondrial energy metabolism to the induction of the unfolded protein response. J Biol Chem (2011) 286(6):4081-9. doi:10.1074/jbc.M110.134106
-
(2011)
J Biol Chem
, vol.286
, Issue.6
, pp. 4081-4089
-
-
Burkart, A.1
Shi, X.2
Chouinard, M.3
Corvera, S.4
-
125
-
-
0017665008
-
Induction of two transformation-sensitive membrane polypeptides in normal fibroblasts by a block in glycoprotein synthesis or glucose deprivation
-
Pouyssegur J, Shiu RP, Pastan I. Induction of two transformation-sensitive membrane polypeptides in normal fibroblasts by a block in glycoprotein synthesis or glucose deprivation. Cell (1977) 11(4):941-7. doi:10.1016/0092-8674(77)90305-1
-
(1977)
Cell
, vol.11
, Issue.4
, pp. 941-947
-
-
Pouyssegur, J.1
Shiu, R.P.2
Pastan, I.3
-
126
-
-
77950343252
-
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
-
Hotamisligil GS. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell (2010) 140(6):900-17. doi:10.1016/j.cell.2010.02.034
-
(2010)
Cell
, vol.140
, Issue.6
, pp. 900-917
-
-
Hotamisligil, G.S.1
-
127
-
-
0034973982
-
Translational control is required for the unfolded protein response and in vivo glucose homeostasis
-
Scheuner D, Song B, McEwen E, Liu C, Laybutt R, Gillespie P, et al. Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol Cell (2001) 7(6):1165-76. doi:10.1016/S1097-2765(01)00265-9
-
(2001)
Mol Cell
, vol.7
, Issue.6
, pp. 1165-1176
-
-
Scheuner, D.1
Song, B.2
McEwen, E.3
Liu, C.4
Laybutt, R.5
Gillespie, P.6
-
128
-
-
37149012111
-
Induction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide
-
Huang CJ, Haataja L, Gurlo T, Butler AE, Wu X, Soeller WC, et al. Induction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide. Am J Physiol Endocrinol Metab (2007) 293(6):E1656-62. doi:10.1152/ajpendo.00318.2007
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
, Issue.6
, pp. E1656-E1662
-
-
Huang, C.J.1
Haataja, L.2
Gurlo, T.3
Butler, A.E.4
Wu, X.5
Soeller, W.C.6
-
129
-
-
9244231766
-
Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress
-
Kharroubi I, Ladrière L, Cardozo AK, Dogusan Z, Cnop M, Eizirik DL. Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress. Endocrinology (2004) 145(11):5087-96. doi:10.1210/en.2004-0478
-
(2004)
Endocrinology
, vol.145
, Issue.11
, pp. 5087-5096
-
-
Kharroubi, I.1
Ladrière, L.2
Cardozo, A.K.3
Dogusan, Z.4
Cnop, M.5
Eizirik, D.L.6
-
130
-
-
33845575826
-
Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death
-
Borradaile NM, Han X, Harp JD, Gale SE, Ory DS, Schaffer JE. Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death. J Lipid Res (2006) 47(12):2726-37. doi:10.1194/jlr.M600299-JLR200
-
(2006)
J Lipid Res
, vol.47
, Issue.12
, pp. 2726-2737
-
-
Borradaile, N.M.1
Han, X.2
Harp, J.D.3
Gale, S.E.4
Ory, D.S.5
Schaffer, J.E.6
-
131
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science (2004) 306(5695):457-61. doi:10.1126/science.1103160
-
(2004)
Science
, vol.306
, Issue.5695
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
-
132
-
-
0034968330
-
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival
-
Harding HP, Zeng H, Zhang Y, Jungries R, Chung P, Plesken H, et al. Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival. Mol Cell (2001) 7(6):1153-63. doi:10.1016/S1097-2765(01)00264-7
-
(2001)
Mol Cell
, vol.7
, Issue.6
, pp. 1153-1163
-
-
Harding, H.P.1
Zeng, H.2
Zhang, Y.3
Jungries, R.4
Chung, P.5
Plesken, H.6
-
133
-
-
19944430402
-
Involvement of endoplasmic reticulum stress in insulin resistance and diabetes
-
Nakatani Y, Kaneto H, Kawamori D, Yoshiuchi K, Hatazaki M, Matsuoka TA, et al. Involvement of endoplasmic reticulum stress in insulin resistance and diabetes. J Biol Chem (2005) 280(1):847-51. doi:10.1074/jbc.M411860200
-
(2005)
J Biol Chem
, vol.280
, Issue.1
, pp. 847-851
-
-
Nakatani, Y.1
Kaneto, H.2
Kawamori, D.3
Yoshiuchi, K.4
Hatazaki, M.5
Matsuoka, T.A.6
-
134
-
-
67649450485
-
Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells
-
Back SH, Scheuner D, Han J, Song B, Ribick M, Wang J, et al. Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells. Cell Metab (2009) 10(1):13-26. doi:10.1016/j.cmet.2009.06.002
-
(2009)
Cell Metab
, vol.10
, Issue.1
, pp. 13-26
-
-
Back, S.H.1
Scheuner, D.2
Han, J.3
Song, B.4
Ribick, M.5
Wang, J.6
-
135
-
-
34249857603
-
Salicylates trigger protein synthesis inhibition in a protein kinase R-like endoplasmic reticulum kinase-dependent manner
-
Silva AM, Wang D, Komar AA, Castilho BA, Williams BR. Salicylates trigger protein synthesis inhibition in a protein kinase R-like endoplasmic reticulum kinase-dependent manner. J Biol Chem (2007) 282(14):10164-71. doi:10.1074/jbc.M609996200
-
(2007)
J Biol Chem
, vol.282
, Issue.14
, pp. 10164-10171
-
-
Silva, A.M.1
Wang, D.2
Komar, A.A.3
Castilho, B.A.4
Williams, B.R.5
-
136
-
-
0035881317
-
Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor gamma and mediated by inhibition of translation initiation
-
Palakurthi SS, Aktas H, Grubissich LM, Mortensen RM, Halperin JA. Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor gamma and mediated by inhibition of translation initiation. Cancer Res (2001) 61(16):6213-8
-
(2001)
Cancer Res
, vol.61
, Issue.16
, pp. 6213-6218
-
-
Palakurthi, S.S.1
Aktas, H.2
Grubissich, L.M.3
Mortensen, R.M.4
Halperin, J.A.5
-
137
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, Smith RO, et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science (2006) 313(5790):1137-40. doi:10.1126/science.1128294
-
(2006)
Science
, vol.313
, Issue.5790
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
-
138
-
-
38149136598
-
Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents
-
Ota T, Gayet C, Ginsberg HN. Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents. J Clin Invest (2008) 118(1):316-32. doi:10.1172/JCI32752
-
(2008)
J Clin Invest
, vol.118
, Issue.1
, pp. 316-332
-
-
Ota, T.1
Gayet, C.2
Ginsberg, H.N.3
-
139
-
-
71549152580
-
Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis
-
Erbay E, Babaev VR, Mayers JR, Makowski L, Charles KN, Snitow ME, et al. Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis. Nat Med (2009) 15(12):1383-91. doi:10.1038/nm.2067
-
(2009)
Nat Med
, vol.15
, Issue.12
, pp. 1383-1391
-
-
Erbay, E.1
Babaev, V.R.2
Mayers, J.R.3
Makowski, L.4
Charles, K.N.5
Snitow, M.E.6
-
140
-
-
84876486995
-
The unfolded protein response and chemical chaperones reduce protein misfolding and colitis in mice
-
Cao SS, Zimmermann EM, Chuang BM, Song B, Nwokoye A, Wilkinson JE, et al. The unfolded protein response and chemical chaperones reduce protein misfolding and colitis in mice. Gastroenterology (2013) 144(5):989.e-1000.e. doi:10.1053/j.gastro.2013.01.023
-
(2013)
Gastroenterology
, vol.144
, Issue.5
, pp. 989e-1000e
-
-
Cao, S.S.1
Zimmermann, E.M.2
Chuang, B.M.3
Song, B.4
Nwokoye, A.5
Wilkinson, J.E.6
-
141
-
-
74749103667
-
Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice
-
Zhao F, Edwards R, Dizon D, Afrasiabi K, Mastroianni JR, Geyfman M, et al. Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice. Dev Biol (2010) 338(2):270-9. doi:10.1016/j.ydbio.2009.12.008
-
(2010)
Dev Biol
, vol.338
, Issue.2
, pp. 270-279
-
-
Zhao, F.1
Edwards, R.2
Dizon, D.3
Afrasiabi, K.4
Mastroianni, J.R.5
Geyfman, M.6
-
142
-
-
84876998128
-
ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response
-
Heijmans J, van Lidth de Jeude JF, Koo BK, Rosekrans SL, Wielenga MC, van de Wetering M, et al. ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response. Cell Rep (2013) 3(4):1128-39. doi:10.1016/j.celrep.2013.02.031
-
(2013)
Cell Rep
, vol.3
, Issue.4
, pp. 1128-1139
-
-
Heijmans, J.1
van Lidth de Jeude, J.F.2
Koo, B.K.3
Rosekrans, S.L.4
Wielenga, M.C.5
van de Wetering, M.6
-
143
-
-
84943415049
-
Differential molecular and cellular responses of GLP-1 secreting L-cells and pancreatic alpha cells to glucotoxicity and lipotoxicity
-
Vasu S, Moffett RC, McClenaghan NH, Flatt PR. Differential molecular and cellular responses of GLP-1 secreting L-cells and pancreatic alpha cells to glucotoxicity and lipotoxicity. Exp Cell Res (2015) 336(1):100-8. doi:10.1016/j.yexcr.2015.05.022
-
(2015)
Exp Cell Res
, vol.336
, Issue.1
, pp. 100-108
-
-
Vasu, S.1
Moffett, R.C.2
McClenaghan, N.H.3
Flatt, P.R.4
-
144
-
-
84875142060
-
Bile-acid-mediated decrease in endoplasmic reticulum stress: a potential contributor to the metabolic benefits of ileal interposition surgery in UCD-T2DM rats
-
Cummings BP, Bettaieb A, Graham JL, Kim J, Ma F, Shibata N, et al. Bile-acid-mediated decrease in endoplasmic reticulum stress: a potential contributor to the metabolic benefits of ileal interposition surgery in UCD-T2DM rats. Dis Model Mech (2013) 6(2):443-56. doi:10.1242/dmm.010421
-
(2013)
Dis Model Mech
, vol.6
, Issue.2
, pp. 443-456
-
-
Cummings, B.P.1
Bettaieb, A.2
Graham, J.L.3
Kim, J.4
Ma, F.5
Shibata, N.6
-
145
-
-
3242664636
-
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
-
Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell (2004) 118(2):229-41. doi:10.1016/j.cell.2004.07.002
-
(2004)
Cell
, vol.118
, Issue.2
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
Edberg, S.4
Medzhitov, R.5
-
146
-
-
84875083047
-
Adaptive immunity alters distinct host feeding pathways during nematode induced inflammation, a novel mechanism in parasite expulsion
-
Worthington JJ, Samuelson LC, Grencis RK, McLaughlin JT. Adaptive immunity alters distinct host feeding pathways during nematode induced inflammation, a novel mechanism in parasite expulsion. PLoS Pathog (2013) 9(1):e1003122. doi:10.1371/journal.ppat.1003122
-
(2013)
PLoS Pathog
, vol.9
, Issue.1
-
-
Worthington, J.J.1
Samuelson, L.C.2
Grencis, R.K.3
McLaughlin, J.T.4
-
147
-
-
84888201738
-
Enteroendocrine cells in gastrointestinal pathophysiology
-
Harrison E, Lal S, McLaughlin JT. Enteroendocrine cells in gastrointestinal pathophysiology. Curr Opin Pharmacol (2013) 13(6):941-5. doi:10.1016/j.coph.2013.09.012
-
(2013)
Curr Opin Pharmacol
, vol.13
, Issue.6
, pp. 941-945
-
-
Harrison, E.1
Lal, S.2
McLaughlin, J.T.3
-
148
-
-
34447553459
-
Immunohistochemical study on the neuroendocrine system of the digestive tract of turbot, Scophthalmus maximus (L.), infected by Enteromyxum scophthalmi (Myxozoa)
-
Bermudez R, Vigliano F, Quiroga MI, Nieto JM, Bosi G, Domeneghini C. Immunohistochemical study on the neuroendocrine system of the digestive tract of turbot, Scophthalmus maximus (L.), infected by Enteromyxum scophthalmi (Myxozoa). Fish Shellfish Immunol (2007) 22(3):252-63. doi:10.1016/j.fsi.2006.05.006
-
(2007)
Fish Shellfish Immunol
, vol.22
, Issue.3
, pp. 252-263
-
-
Bermudez, R.1
Vigliano, F.2
Quiroga, M.I.3
Nieto, J.M.4
Bosi, G.5
Domeneghini, C.6
-
149
-
-
34347204910
-
CD4+ T cell-mediated immunological control of enterochromaffin cell hyperplasia and 5-hydroxytryptamine production in enteric infection
-
Wang H, Steeds J, Motomura Y, Deng Y, Verma-Gandhu M, El-Sharkawy RT, et al. CD4+ T cell-mediated immunological control of enterochromaffin cell hyperplasia and 5-hydroxytryptamine production in enteric infection. Gut (2007) 56(7):949-57. doi:10.1136/gut.2006.103226
-
(2007)
Gut
, vol.56
, Issue.7
, pp. 949-957
-
-
Wang, H.1
Steeds, J.2
Motomura, Y.3
Deng, Y.4
Verma-Gandhu, M.5
El-Sharkawy, R.T.6
-
150
-
-
84869752888
-
High densities of serotonin and peptide YY cells in the colon of patients with lymphocytic colitis
-
El-Salhy M, Gundersen D, Hatlebakk JG, Hausken T. High densities of serotonin and peptide YY cells in the colon of patients with lymphocytic colitis. World J Gastroenterol (2012) 18(42):6070-5. doi:10.3748/wjg.v18.i42.6070
-
(2012)
World J Gastroenterol
, vol.18
, Issue.42
, pp. 6070-6075
-
-
El-Salhy, M.1
Gundersen, D.2
Hatlebakk, J.G.3
Hausken, T.4
-
151
-
-
84871626306
-
Chromogranin A cell density as a diagnostic marker for lymphocytic colitis
-
El-Salhy M, Gundersen D, Hatlebakk JG, Hausken T. Chromogranin A cell density as a diagnostic marker for lymphocytic colitis. Dig Dis Sci (2012) 57(12):3154-9. doi:10.1007/s10620-012-2249-6
-
(2012)
Dig Dis Sci
, vol.57
, Issue.12
, pp. 3154-3159
-
-
El-Salhy, M.1
Gundersen, D.2
Hatlebakk, J.G.3
Hausken, T.4
-
152
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet (2007) 39(5):596-604. doi:10.1038/ng2032
-
(2007)
Nat Genet
, vol.39
, Issue.5
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
Silverberg, M.S.4
Goyette, P.5
Huett, A.6
-
153
-
-
41149103489
-
Autoantibodies against ubiquitination factor E4A (UBE4A) are associated with severity of Crohn's disease
-
Sakiyama T, Fujita H, Tsubouchi H. Autoantibodies against ubiquitination factor E4A (UBE4A) are associated with severity of Crohn's disease. Inflamm Bowel Dis (2008) 14(3):310-7. doi:10.1002/ibd.20328
-
(2008)
Inflamm Bowel Dis
, vol.14
, Issue.3
, pp. 310-317
-
-
Sakiyama, T.1
Fujita, H.2
Tsubouchi, H.3
-
154
-
-
84865795136
-
Enteroendocrine cells in terminal ileal Crohn's disease
-
Moran GW, Pennock J, McLaughlin JT. Enteroendocrine cells in terminal ileal Crohn's disease. J Crohns Colitis (2012) 6(9):871-80. doi:10.1016/j.crohns.2012.01.013
-
(2012)
J Crohns Colitis
, vol.6
, Issue.9
, pp. 871-880
-
-
Moran, G.W.1
Pennock, J.2
McLaughlin, J.T.3
-
155
-
-
67649637125
-
Rejection reversibly alters enteroendocrine cell renewal in the transplanted small intestine
-
Fishbein TM, Novitskiy G, Lough DM, Matsumoto C, Kaufman SS, Shetty K, et al. Rejection reversibly alters enteroendocrine cell renewal in the transplanted small intestine. Am J Transplant (2009) 9(7):1620-8. doi:10.1111/j.1600-6143.2009.02681.x
-
(2009)
Am J Transplant
, vol.9
, Issue.7
, pp. 1620-1628
-
-
Fishbein, T.M.1
Novitskiy, G.2
Lough, D.M.3
Matsumoto, C.4
Kaufman, S.S.5
Shetty, K.6
-
156
-
-
84932618204
-
Intestinal neuroendocrine cells and goblet cells are mediators of IL-17A-amplified epithelial IL-17C production in human inflammatory bowel disease
-
Friedrich M, Diegelmann J, Schauber J, Auernhammer CJ, Brand S. Intestinal neuroendocrine cells and goblet cells are mediators of IL-17A-amplified epithelial IL-17C production in human inflammatory bowel disease. Mucosal Immunol (2015) 8(4):943-58. doi:10.1038/mi.2014.124
-
(2015)
Mucosal Immunol
, vol.8
, Issue.4
, pp. 943-958
-
-
Friedrich, M.1
Diegelmann, J.2
Schauber, J.3
Auernhammer, C.J.4
Brand, S.5
-
157
-
-
84885576350
-
Circulating leptin and adiponectin and their relation to glucose metabolism in children with Crohn's disease and ulcerative colitis
-
Chouliaras G, Panayotou I, Margoni D, Mantzou E, Pervanidou P, Manios Y, et al. Circulating leptin and adiponectin and their relation to glucose metabolism in children with Crohn's disease and ulcerative colitis. Pediatr Res (2013) 74(4):420-6. doi:10.1038/pr.2013.114
-
(2013)
Pediatr Res
, vol.74
, Issue.4
, pp. 420-426
-
-
Chouliaras, G.1
Panayotou, I.2
Margoni, D.3
Mantzou, E.4
Pervanidou, P.5
Manios, Y.6
-
158
-
-
84901985892
-
Systemic metabolic signaling in acute and chronic gastrointestinal inflammation of inflammatory bowel diseases
-
Karrasch T, Obermeier F, Straub RH. Systemic metabolic signaling in acute and chronic gastrointestinal inflammation of inflammatory bowel diseases. Horm Metab Res (2014) 46(6):445-51. doi:10.1055/s-0034-1374587
-
(2014)
Horm Metab Res
, vol.46
, Issue.6
, pp. 445-451
-
-
Karrasch, T.1
Obermeier, F.2
Straub, R.H.3
-
159
-
-
84902209342
-
Increased pulse wave velocity and relationship with inflammation, insulin, and insulin resistance in inflammatory bowel disease
-
Korkmaz H, Sahin F, Ipekci SH, Temel T, Kebapcilar L. Increased pulse wave velocity and relationship with inflammation, insulin, and insulin resistance in inflammatory bowel disease. Eur J Gastroenterol Hepatol (2014) 26(7):725-32. doi:10.1097/MEG.0000000000000104
-
(2014)
Eur J Gastroenterol Hepatol
, vol.26
, Issue.7
, pp. 725-732
-
-
Korkmaz, H.1
Sahin, F.2
Ipekci, S.H.3
Temel, T.4
Kebapcilar, L.5
-
160
-
-
58149472945
-
Circulating adipokines and the protective effects of hyperinsulinemia in inflammatory bowel disease
-
Valentini L, Wirth EK, Schweizer U, Hengstermann S, Schaper L, Koernicke T, et al. Circulating adipokines and the protective effects of hyperinsulinemia in inflammatory bowel disease. Nutrition (2009) 25(2):172-81. doi:10.1016/j.nut.2008.07.020
-
(2009)
Nutrition
, vol.25
, Issue.2
, pp. 172-181
-
-
Valentini, L.1
Wirth, E.K.2
Schweizer, U.3
Hengstermann, S.4
Schaper, L.5
Koernicke, T.6
-
161
-
-
36249016379
-
Resistin is an inflammatory marker of inflammatory bowel disease in humans
-
Konrad A, Lehrke M, Schachinger V, Seibold F, Stark R, Ochsenkühn T, et al. Resistin is an inflammatory marker of inflammatory bowel disease in humans. Eur J Gastroenterol Hepatol (2007) 19(12):1070-4. doi:10.1097/MEG.0b013e3282f16251
-
(2007)
Eur J Gastroenterol Hepatol
, vol.19
, Issue.12
, pp. 1070-1074
-
-
Konrad, A.1
Lehrke, M.2
Schachinger, V.3
Seibold, F.4
Stark, R.5
Ochsenkühn, T.6
-
162
-
-
29744458362
-
Increased insulin resistance and beta cell activity in patients with Crohn's disease
-
Bregenzer N, Hartmann A, Strauch U, Schölmerich J, Andus T, Bollheimer LC. Increased insulin resistance and beta cell activity in patients with Crohn's disease. Inflamm Bowel Dis (2006) 12(1):53-6. doi:10.1097/01.MIB.0000195975.97673.f5
-
(2006)
Inflamm Bowel Dis
, vol.12
, Issue.1
, pp. 53-56
-
-
Bregenzer, N.1
Hartmann, A.2
Strauch, U.3
Schölmerich, J.4
Andus, T.5
Bollheimer, L.C.6
-
163
-
-
84877127350
-
Crohn's disease affecting the small bowel is associated with reduced appetite and elevated levels of circulating gut peptides
-
Moran GW, Leslie FC, McLaughlin JT. Crohn's disease affecting the small bowel is associated with reduced appetite and elevated levels of circulating gut peptides. Clin Nutr (2013) 32(3):404-11. doi:10.1016/j.clnu.2012.08.024
-
(2013)
Clin Nutr
, vol.32
, Issue.3
, pp. 404-411
-
-
Moran, G.W.1
Leslie, F.C.2
McLaughlin, J.T.3
-
164
-
-
84954320706
-
Gastric emptying and disease activity in inflammatory bowel disease
-
Keller J, Binnewies U, Rösch M, Juul Holst J, Beglinger C, Andresen V, et al. Gastric emptying and disease activity in inflammatory bowel disease. Eur J Clin Invest (2015) 45:1234-42. doi:10.1111/eci.12542
-
(2015)
Eur J Clin Invest
, vol.45
, pp. 1234-1242
-
-
Keller, J.1
Binnewies, U.2
Rösch, M.3
Juul Holst, J.4
Beglinger, C.5
Andresen, V.6
-
165
-
-
0020521595
-
Gut hormones in inflammatory bowel disease
-
Besterman HS, Mallinson CN, Modigliani R, Christofides ND, Pera A, Ponti V, et al. Gut hormones in inflammatory bowel disease. Scand J Gastroenterol (1983) 18(7):845-52. doi:10.3109/00365528309182104
-
(1983)
Scand J Gastroenterol
, vol.18
, Issue.7
, pp. 845-852
-
-
Besterman, H.S.1
Mallinson, C.N.2
Modigliani, R.3
Christofides, N.D.4
Pera, A.5
Ponti, V.6
-
166
-
-
0030728376
-
Colonic endocrine cells in inflammatory bowel disease
-
El-Salhy M, Danielsson A, Stenling R, Grimelius L. Colonic endocrine cells in inflammatory bowel disease. J Intern Med (1997) 242(5):413-9. doi:10.1046/j.1365-2796.1997.00237.x
-
(1997)
J Intern Med
, vol.242
, Issue.5
, pp. 413-419
-
-
El-Salhy, M.1
Danielsson, A.2
Stenling, R.3
Grimelius, L.4
-
167
-
-
72249097354
-
Mechanisms of gastric emptying disturbances in chronic and acute inflammation of the distal gastrointestinal tract
-
Keller J, Beglinger C, Holst JJ, Andresen V, Layer P. Mechanisms of gastric emptying disturbances in chronic and acute inflammation of the distal gastrointestinal tract. Am J Physiol Gastrointest Liver Physiol (2009) 297(5):G861-8. doi:10.1152/ajpgi.00145.2009
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.297
, Issue.5
, pp. G861-G868
-
-
Keller, J.1
Beglinger, C.2
Holst, J.J.3
Andresen, V.4
Layer, P.5
-
168
-
-
0033998750
-
Circulating levels of glucagon-like peptide-2 in human subjects with inflammatory bowel disease
-
Xiao Q, Boushey RP, Cino M, Drucker DJ, Brubaker PL. Circulating levels of glucagon-like peptide-2 in human subjects with inflammatory bowel disease. Am J Physiol Regul Integr Comp Physiol (2000) 278(4):R1057-63
-
(2000)
Am J Physiol Regul Integr Comp Physiol
, vol.278
, Issue.4
, pp. R1057-R1063
-
-
Xiao, Q.1
Boushey, R.P.2
Cino, M.3
Drucker, D.J.4
Brubaker, P.L.5
-
169
-
-
0023142089
-
Increased populations of endocrine cells in Crohn's ileitis
-
Bishop AE, Pietroletti R, Taat CW, Brummelkamp WH, Polak JM. Increased populations of endocrine cells in Crohn's ileitis. Virchows Arch A Pathol Anat Histopathol (1987) 410(5):391-6. doi:10.1007/BF00712758
-
(1987)
Virchows Arch A Pathol Anat Histopathol
, vol.410
, Issue.5
, pp. 391-396
-
-
Bishop, A.E.1
Pietroletti, R.2
Taat, C.W.3
Brummelkamp, W.H.4
Polak, J.M.5
-
170
-
-
84862768978
-
Dipeptidyl peptidase-4 expression is reduced in Crohn's disease
-
Moran GW, O'Neill C, Padfield P, McLaughlin JT. Dipeptidyl peptidase-4 expression is reduced in Crohn's disease. Regul Pept (2012) 177(1-3):40-5. doi:10.1016/j.regpep.2012.04.006
-
(2012)
Regul Pept
, vol.177
, Issue.1-3
, pp. 40-45
-
-
Moran, G.W.1
O'Neill, C.2
Padfield, P.3
McLaughlin, J.T.4
-
171
-
-
84884541899
-
Dipeptidyl peptidase-4 inhibitor anagliptin facilitates restoration of dextran sulfate sodium-induced colitis
-
Mimura S, Ando T, Ishiguro K, Maeda O, Watanabe O, Ujihara M, et al. Dipeptidyl peptidase-4 inhibitor anagliptin facilitates restoration of dextran sulfate sodium-induced colitis. Scand J Gastroenterol (2013) 48(10):1152-9. doi:10.3109/00365521.2013.832366
-
(2013)
Scand J Gastroenterol
, vol.48
, Issue.10
, pp. 1152-1159
-
-
Mimura, S.1
Ando, T.2
Ishiguro, K.3
Maeda, O.4
Watanabe, O.5
Ujihara, M.6
-
172
-
-
84863115292
-
Disruption of the murine Glp2r impairs Paneth cell function and increases susceptibility to small bowel enteritis
-
Lee SJ, Lee J, Li KK, Holland D, Maughan H, Guttman DS, et al. Disruption of the murine Glp2r impairs Paneth cell function and increases susceptibility to small bowel enteritis. Endocrinology (2012) 153(3):1141-51. doi:10.1210/en.2011-1954
-
(2012)
Endocrinology
, vol.153
, Issue.3
, pp. 1141-1151
-
-
Lee, S.J.1
Lee, J.2
Li, K.K.3
Holland, D.4
Maughan, H.5
Guttman, D.S.6
-
173
-
-
84890493862
-
Purified PEGylated porcine glucagon-like peptide-2 reduces the severity of colonic injury in a murine model of experimental colitis
-
Qi KK, Wu J, Wan J, Men XM, Xu ZW. Purified PEGylated porcine glucagon-like peptide-2 reduces the severity of colonic injury in a murine model of experimental colitis. Peptides (2014) 52:11-8. doi:10.1016/j.peptides.2013.11.012
-
(2014)
Peptides
, vol.52
, pp. 11-18
-
-
Qi, K.K.1
Wu, J.2
Wan, J.3
Men, X.M.4
Xu, Z.W.5
-
174
-
-
0032714919
-
Glucagon-like peptide 2 decreases mortality and reduces the severity of indomethacin-induced murine enteritis
-
Boushey RP, Yusta B, Drucker DJ. Glucagon-like peptide 2 decreases mortality and reduces the severity of indomethacin-induced murine enteritis. Am J Physiol (1999) 277(5 Pt 1):E937-47
-
(1999)
Am J Physiol
, vol.277
, Issue.5
, pp. E937-E947
-
-
Boushey, R.P.1
Yusta, B.2
Drucker, D.J.3
-
175
-
-
0034113232
-
Treatment of inflammatory bowel disease in a rodent model with the intestinal growth factor glucagon-like peptide-2
-
Alavi K, Schwartz MZ, Palazzo JP, Prasad R. Treatment of inflammatory bowel disease in a rodent model with the intestinal growth factor glucagon-like peptide-2. J Pediatr Surg (2000) 35(6):847-51. doi:10.1053/jpsu.2000.6861
-
(2000)
J Pediatr Surg
, vol.35
, Issue.6
, pp. 847-851
-
-
Alavi, K.1
Schwartz, M.Z.2
Palazzo, J.P.3
Prasad, R.4
-
176
-
-
0032621235
-
Human [Gly2]GLP-2 reduces the severity of colonic injury in a murine model of experimental colitis
-
Drucker DJ, Yusta B, Boushey RP, DeForest L, Brubaker PL. Human [Gly2]GLP-2 reduces the severity of colonic injury in a murine model of experimental colitis. Am J Physiol (1999) 276(1 Pt 1):G79-91
-
(1999)
Am J Physiol
, vol.276
, Issue.1
, pp. G79-G91
-
-
Drucker, D.J.1
Yusta, B.2
Boushey, R.P.3
DeForest, L.4
Brubaker, P.L.5
-
177
-
-
77952679996
-
Teduglutide, a novel mucosally active analog of glucagon-like peptide-2 (GLP-2) for the treatment of moderate to severe Crohn's disease
-
Buchman AL, Katz S, Fang JC, Bernstein CN, Abou-Assi SG, Teduglutide Study Group. Teduglutide, a novel mucosally active analog of glucagon-like peptide-2 (GLP-2) for the treatment of moderate to severe Crohn's disease. Inflamm Bowel Dis (2010) 16(6):962-73. doi:10.1002/ibd.21117
-
(2010)
Inflamm Bowel Dis
, vol.16
, Issue.6
, pp. 962-973
-
-
Buchman, A.L.1
Katz, S.2
Fang, J.C.3
Bernstein, C.N.4
Abou-Assi, S.G.5
-
178
-
-
79958187560
-
Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome
-
Jeppesen PB, Gilroy R, Pertkiewicz M, Allard JP, Messing B, O'Keefe SJ. Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome. Gut (2011) 60(7):902-14. doi:10.1136/gut.2010.218271
-
(2011)
Gut
, vol.60
, Issue.7
, pp. 902-914
-
-
Jeppesen, P.B.1
Gilroy, R.2
Pertkiewicz, M.3
Allard, J.P.4
Messing, B.5
O'Keefe, S.J.6
-
179
-
-
84869881880
-
Teduglutide reduces need for parenteral support among patients with short bowel syndrome with intestinal failure
-
Jeppesen PB, Pertkiewicz M, Messing B, Iyer K, Seidner DL, O'keefe SJ, et al. Teduglutide reduces need for parenteral support among patients with short bowel syndrome with intestinal failure. Gastroenterology (2012) 143(6):1473.e-81.e. doi:10.1053/j.gastro.2012.09.007
-
(2012)
Gastroenterology
, vol.143
, Issue.6
, pp. 1473e-1481e
-
-
Jeppesen, P.B.1
Pertkiewicz, M.2
Messing, B.3
Iyer, K.4
Seidner, D.L.5
O'keefe, S.J.6
-
180
-
-
68449097985
-
WNT/beta-catenin increases the production of incretins by entero-endocrine cells
-
García-Martínez JM, Chocarro-Calvo A, Moya CM, García-Jiménez C. WNT/beta-catenin increases the production of incretins by entero-endocrine cells. Diabetologia (2009) 52(9):1913-24. doi:10.1007/s00125-009-1429-1
-
(2009)
Diabetologia
, vol.52
, Issue.9
, pp. 1913-1924
-
-
García-Martínez, J.M.1
Chocarro-Calvo, A.2
Moya, C.M.3
García-Jiménez, C.4
-
181
-
-
51249114497
-
WNT signalling is both an inducer and effector of glucagon-like peptide-1
-
Gustafson B, Smith U. WNT signalling is both an inducer and effector of glucagon-like peptide-1. Diabetologia (2008) 51(10):1768-70. doi:10.1007/s00125-008-1109-6
-
(2008)
Diabetologia
, vol.51
, Issue.10
, pp. 1768-1770
-
-
Gustafson, B.1
Smith, U.2
-
182
-
-
17444423289
-
Wnt signaling in the intestinal epithelium: from endoderm to cancer
-
Gregorieff A, Clevers H. Wnt signaling in the intestinal epithelium: from endoderm to cancer. Genes Dev (2005) 19(8):877-90. doi:10.1101/gad.1295405
-
(2005)
Genes Dev
, vol.19
, Issue.8
, pp. 877-890
-
-
Gregorieff, A.1
Clevers, H.2
-
183
-
-
35748957503
-
The physiology of glucagon-like peptide 1
-
Holst JJ. The physiology of glucagon-like peptide 1. Physiol Rev (2007) 87(4):1409-39. doi:10.1152/physrev.00034.2006
-
(2007)
Physiol Rev
, vol.87
, Issue.4
, pp. 1409-1439
-
-
Holst, J.J.1
-
184
-
-
0032944601
-
The influence of the colon on postprandial glucagon-like peptide 1 (7-36) amide concentration in man
-
Robertson MD, Livesey G, Morgan LM, Hampton SM, Mathers JC. The influence of the colon on postprandial glucagon-like peptide 1 (7-36) amide concentration in man. J Endocrinol (1999) 161(1):25-31. doi:10.1677/joe.0.1610025
-
(1999)
J Endocrinol
, vol.161
, Issue.1
, pp. 25-31
-
-
Robertson, M.D.1
Livesey, G.2
Morgan, L.M.3
Hampton, S.M.4
Mathers, J.C.5
-
185
-
-
0022515907
-
Enteroendocrine cell hyperplasia, carcinoid tumours and adenocarcinoma in long-standing ulcerative colitis
-
Gledhill A, Hall PA, Cruse JP, Pollock DJ. Enteroendocrine cell hyperplasia, carcinoid tumours and adenocarcinoma in long-standing ulcerative colitis. Histopathology (1986) 10(5):501-8. doi:10.1111/j.1365-2559.1986.tb02501.x
-
(1986)
Histopathology
, vol.10
, Issue.5
, pp. 501-508
-
-
Gledhill, A.1
Hall, P.A.2
Cruse, J.P.3
Pollock, D.J.4
-
186
-
-
84874786762
-
Lactocepin as a protective microbial structure in the context of IBD
-
Hormannsperger G, von Schillde MA, Haller D. Lactocepin as a protective microbial structure in the context of IBD. Gut Microbes (2013) 4(2):152-7. doi:10.4161/gmic.23444
-
(2013)
Gut Microbes
, vol.4
, Issue.2
, pp. 152-157
-
-
Hormannsperger, G.1
von Schillde, M.A.2
Haller, D.3
-
187
-
-
84902300630
-
Gut microbiota, probiotics and diabetes
-
Gomes AC, Bueno AA, de Souza RG, Mota JF. Gut microbiota, probiotics and diabetes. Nutr J (2014) 13:60. doi:10.1186/1475-2891-13-60
-
(2014)
Nutr J
, vol.13
, pp. 60
-
-
Gomes, A.C.1
Bueno, A.A.2
de Souza, R.G.3
Mota, J.F.4
-
188
-
-
35848947008
-
Modulation of glucagon-like peptide 1 and energy metabolism by inulin and oligofructose: experimental data
-
Delzenne NM, Cani PD, Neyrinck AM. Modulation of glucagon-like peptide 1 and energy metabolism by inulin and oligofructose: experimental data. J Nutr (2007) 137(11 Suppl):2547S-51S
-
(2007)
J Nutr
, vol.137
, Issue.11
, pp. 2547S-2551S
-
-
Delzenne, N.M.1
Cani, P.D.2
Neyrinck, A.M.3
-
189
-
-
0028026180
-
Immunocytochemical study of intestinal endocrine cells in germ-free mice
-
Nogueira AM, Barbosa AJ. Immunocytochemical study of intestinal endocrine cells in germ-free mice. Eur J Histochem (1994) 38(3):213-8
-
(1994)
Eur J Histochem
, vol.38
, Issue.3
, pp. 213-218
-
-
Nogueira, A.M.1
Barbosa, A.J.2
-
190
-
-
84907228623
-
Evidence for the gut microbiota short-chain fatty acids as key pathophysiological molecules improving diabetes
-
Puddu A, Sanguineti R, Montecucco F, Viviani GL. Evidence for the gut microbiota short-chain fatty acids as key pathophysiological molecules improving diabetes. Mediators Inflamm (2014) 2014:162021. doi:10.1155/2014/162021
-
(2014)
Mediators Inflamm
, vol.2014
-
-
Puddu, A.1
Sanguineti, R.2
Montecucco, F.3
Viviani, G.L.4
-
191
-
-
79955932718
-
Potential beneficial effects of butyrate in intestinal and extraintestinal diseases
-
Canani RB, Costanzo MD, Leone L, Pedata M, Meli R, Calignano A. Potential beneficial effects of butyrate in intestinal and extraintestinal diseases. World J Gastroenterol (2011) 17(12):1519-28. doi:10.3748/wjg.v17.i12
-
(2011)
World J Gastroenterol
, vol.17
, Issue.12
, pp. 1519-1528
-
-
Canani, R.B.1
Costanzo, M.D.2
Leone, L.3
Pedata, M.4
Meli, R.5
Calignano, A.6
-
192
-
-
84892874108
-
Effects of short chain fatty acid producing bacteria on epigenetic regulation of FFAR3 in type 2 diabetes and obesity
-
Remely M, Aumueller E, Merold C, Dworzak S, Hippe B, Zanner J, et al. Effects of short chain fatty acid producing bacteria on epigenetic regulation of FFAR3 in type 2 diabetes and obesity. Gene (2014) 537(1):85-92. doi:10.1016/j.gene.2013.11.081
-
(2014)
Gene
, vol.537
, Issue.1
, pp. 85-92
-
-
Remely, M.1
Aumueller, E.2
Merold, C.3
Dworzak, S.4
Hippe, B.5
Zanner, J.6
-
193
-
-
84883418106
-
Beneficial metabolic effects of a probiotic via butyrate-induced GLP-1 hormone secretion
-
Yadav H, Lee JH, Lloyd J, Walter P, Rane SG. Beneficial metabolic effects of a probiotic via butyrate-induced GLP-1 hormone secretion. J Biol Chem (2013) 288(35):25088-97. doi:10.1074/jbc.M113.452516
-
(2013)
J Biol Chem
, vol.288
, Issue.35
, pp. 25088-25097
-
-
Yadav, H.1
Lee, J.H.2
Lloyd, J.3
Walter, P.4
Rane, S.G.5
-
194
-
-
80755152887
-
Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice
-
Everard A, Lazarevic V, Derrien M, Girard M, Muccioli GG, Neyrinck AM, et al. Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice. Diabetes (2011) 60(11):2775-86. doi:10.2337/db11-0227
-
(2011)
Diabetes
, vol.60
, Issue.11
, pp. 2775-2786
-
-
Everard, A.1
Lazarevic, V.2
Derrien, M.3
Girard, M.4
Muccioli, G.G.5
Neyrinck, A.M.6
-
195
-
-
5444248493
-
Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium
-
Derrien M, Vaughan EE, Plugge CM, de Vos WM. Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium. Int J Syst Evol Microbiol (2004) 54(Pt 5):1469-76. doi:10.1099/ijs.0.02873-0
-
(2004)
Int J Syst Evol Microbiol
, vol.54
, pp. 1469-1476
-
-
Derrien, M.1
Vaughan, E.E.2
Plugge, C.M.3
de Vos, W.M.4
-
196
-
-
84878465280
-
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
-
Everard A, Belzer C, Geurts L, Ouwerkerk JP, Druart C, Bindels LB, et al. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc Natl Acad Sci U S A (2013) 110(22):9066-71. doi:10.1073/pnas.1219451110
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.22
, pp. 9066-9071
-
-
Everard, A.1
Belzer, C.2
Geurts, L.3
Ouwerkerk, J.P.4
Druart, C.5
Bindels, L.B.6
-
197
-
-
0000422498
-
The intraluminal phase of fat digestion in man: the lipid content of the micellar and oil phases of intestinal content obtained during fat digestion and absorption
-
Hofmann AF, Borgstroem B. The intraluminal phase of fat digestion in man: the lipid content of the micellar and oil phases of intestinal content obtained during fat digestion and absorption. J Clin Invest (1964) 43:247-57. doi:10.1172/JCI104909
-
(1964)
J Clin Invest
, vol.43
, pp. 247-257
-
-
Hofmann, A.F.1
Borgstroem, B.2
-
198
-
-
70350292362
-
Bile-acid-activated receptors: targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders
-
Fiorucci S, Mencarelli A, Palladino G, Cipriani S. Bile-acid-activated receptors: targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders. Trends Pharmacol Sci (2009) 30(11):570-80. doi:10.1016/j.tips.2009.08.001
-
(2009)
Trends Pharmacol Sci
, vol.30
, Issue.11
, pp. 570-580
-
-
Fiorucci, S.1
Mencarelli, A.2
Palladino, G.3
Cipriani, S.4
-
199
-
-
84922758254
-
Bile acids as metabolic regulators
-
Li T, Chiang JY. Bile acids as metabolic regulators. Curr Opin Gastroenterol (2015) 31(2):159-65. doi:10.1097/MOG.0000000000000156
-
(2015)
Curr Opin Gastroenterol
, vol.31
, Issue.2
, pp. 159-165
-
-
Li, T.1
Chiang, J.Y.2
-
200
-
-
84919725262
-
Intestinal microbiota and type 2 diabetes: from mechanism insights to therapeutic perspective
-
Han JL, Lin HL. Intestinal microbiota and type 2 diabetes: from mechanism insights to therapeutic perspective. World J Gastroenterol (2014) 20(47):17737-45. doi:10.3748/wjg.v20.i47.17737
-
(2014)
World J Gastroenterol
, vol.20
, Issue.47
, pp. 17737-17745
-
-
Han, J.L.1
Lin, H.L.2
-
201
-
-
2542435874
-
Bile acids regulate gluconeogenic gene expression via small heterodimer partner-mediated repression of hepatocyte nuclear factor 4 and Foxo1
-
Yamagata K, Daitoku H, Shimamoto Y, Matsuzaki H, Hirota K, Ishida J, et al. Bile acids regulate gluconeogenic gene expression via small heterodimer partner-mediated repression of hepatocyte nuclear factor 4 and Foxo1. J Biol Chem (2004) 279(22):23158-65. doi:10.1074/jbc.M314322200
-
(2004)
J Biol Chem
, vol.279
, Issue.22
, pp. 23158-23165
-
-
Yamagata, K.1
Daitoku, H.2
Shimamoto, Y.3
Matsuzaki, H.4
Hirota, K.5
Ishida, J.6
-
202
-
-
84873342775
-
Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist
-
Sayin SI, Wahlström A, Felin J, Jäntti S, Marschall HU, Bamberg K, et al. Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist. Cell Metab (2013) 17(2):225-35. doi:10.1016/j.cmet.2013.01.003
-
(2013)
Cell Metab
, vol.17
, Issue.2
, pp. 225-235
-
-
Sayin, S.I.1
Wahlström, A.2
Felin, J.3
Jäntti, S.4
Marschall, H.U.5
Bamberg, K.6
-
203
-
-
33644752102
-
Mechanism of growth inhibition by free bile acids in lactobacilli and bifidobacteria
-
Kurdi P, Kawanishi K, Mizutani K, Yokota A. Mechanism of growth inhibition by free bile acids in lactobacilli and bifidobacteria. J Bacteriol (2006) 188(5):1979-86. doi:10.1128/JB.188.5.1979-1986.2006
-
(2006)
J Bacteriol
, vol.188
, Issue.5
, pp. 1979-1986
-
-
Kurdi, P.1
Kawanishi, K.2
Mizutani, K.3
Yokota, A.4
-
204
-
-
84905273290
-
Bile acid sequestrants in type 2 diabetes: potential effects on GLP1 secretion
-
Sonne DP, Hansen M, Knop FK. Bile acid sequestrants in type 2 diabetes: potential effects on GLP1 secretion. Eur J Endocrinol (2014) 171(2):R47-65. doi:10.1530/EJE-14-0154
-
(2014)
Eur J Endocrinol
, vol.171
, Issue.2
, pp. R47-R65
-
-
Sonne, D.P.1
Hansen, M.2
Knop, F.K.3
-
205
-
-
84895775124
-
Bile acid sequestrants: glucose-lowering mechanisms and efficacy in type 2 diabetes
-
Hansen M, Sonne DP, Knop FK. Bile acid sequestrants: glucose-lowering mechanisms and efficacy in type 2 diabetes. Curr Diab Rep (2014) 14(5):482. doi:10.1007/s11892-014-0482-4
-
(2014)
Curr Diab Rep
, vol.14
, Issue.5
, pp. 482
-
-
Hansen, M.1
Sonne, D.P.2
Knop, F.K.3
-
206
-
-
84923931916
-
Increased GIP signaling induces adipose inflammation via a HIF-1alpha-dependent pathway and impairs insulin sensitivity in mice
-
Chen S, Okahara F, Osaki N, Shimotoyodome A. Increased GIP signaling induces adipose inflammation via a HIF-1alpha-dependent pathway and impairs insulin sensitivity in mice. Am J Physiol Endocrinol Metab (2015) 308(5):E414-25. doi:10.1152/ajpendo.00418.2014
-
(2015)
Am J Physiol Endocrinol Metab
, vol.308
, Issue.5
, pp. E414-E425
-
-
Chen, S.1
Okahara, F.2
Osaki, N.3
Shimotoyodome, A.4
-
207
-
-
84882629237
-
High fat diet accelerates pathogenesis of murine Crohn's disease-like ileitis independently of obesity
-
Gruber L, Kisling S, Lichti P, Martin FP, May S, Klingenspor M, et al. High fat diet accelerates pathogenesis of murine Crohn's disease-like ileitis independently of obesity. PLoS One (2013) 8(8):e71661. doi:10.1371/journal.pone.0071661
-
(2013)
PLoS One
, vol.8
, Issue.8
-
-
Gruber, L.1
Kisling, S.2
Lichti, P.3
Martin, F.P.4
May, S.5
Klingenspor, M.6
-
208
-
-
3042739678
-
Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity
-
Di Gregorio GB, Hensley L, Lu T, Ranganathan G, Kern PA. Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity. Am J Physiol Endocrinol Metab (2004) 287(1):E182-7. doi:10.1152/ajpendo.00189.2003
-
(2004)
Am J Physiol Endocrinol Metab
, vol.287
, Issue.1
, pp. E182-E187
-
-
Di Gregorio, G.B.1
Hensley, L.2
Lu, T.3
Ranganathan, G.4
Kern, P.A.5
-
209
-
-
84947558943
-
Intestinal organoids for assessing nutrient transport, sensing and incretin secretion
-
Zietek T, Rath E, Haller D, Daniel H. Intestinal organoids for assessing nutrient transport, sensing and incretin secretion. Sci Rep (2015) 5:16831. doi:10.1038/srep16831
-
(2015)
Sci Rep
, vol.5
, pp. 16831
-
-
Zietek, T.1
Rath, E.2
Haller, D.3
Daniel, H.4
|