Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance

Metabolism: Clinical and Experimental

Volumn 62, Issue 11, 2013, Pages 1543-1552

  Aroor, Annayya R ^a,c   McKarns, Susan ^b   Demarco, Vincent G ^a,b   Jia, Guanghong ^a,c   Sowers, James R ^a,b,c  

^a UNIVERSITY OF MISSOURI   (United States)

^b University of Missouri   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

DPP 4; Gender; Immunity; Obesity; Uric acid

Indexed keywords

INCRETIN;

AGE DISTRIBUTION; CARDIORENAL SYNDROME; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; HUMAN; IMMUNE RESPONSE; IMMUNOPATHOLOGY; INFLAMMATORY DISEASE; INSULIN RESISTANCE; LYMPHOCYTE; MACROPHAGE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PREMENOPAUSE; PREVALENCE; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVIEW; SYMPATHETIC TONE; UNITED STATES;

(SOD)3; AKT; ANG II; ANG II RECEPTOR BLOCKERS; ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR; ARBS; AT1R; C-JUN KINASE; CARDIOVASCULAR DISEASE; CHRONIC KIDNEY DISEASE; CIRCUMVENTRICULAR ORGANS; CKD; COXSACKIEVIRUS B3; CVB3; CVD; CVO; CYTOKINE SIGNALING 3; DIPETIDYL PEPTIDASE 4; DPP-4; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENOS; ERK1/2; EXTRACELLULAR REGULATED KINASES 1/2; FFAS; FORKHEAD/WINGED HELIX TRANSCRIPTION FACTOR 3; FOXP3; FREE FATTY ACIDS; GENDER; GIP; GLP-1; GLP-1 RECEPTOR; GLP-1R; GLUCAGON LIKE PEPTIDE-1; GLUCOSE-DEPENDENT INSULINOTROPHIC PEPTIDE; HFCS; HIGH-FRUCTOSE CORN SYRUP; IFN-Γ; IL-10; IL-6; IMMUNITY; INSULIN RECEPTOR SUBSTRATE; INTERFERON GAMMA; INTERLEUKIN 10; INTERLEUKIN 6; IRS; JNK; LIPOPOLYSACCHARIDE; LPS; MAMMALIAN TARGET OF RAPAMYCIN; MTOR; NITRIC OXIDE; NO; OBESITY; P70 S6 KINASE; PET; PHOSPHATIDYLINOSITOL 3 KINASE; PI3-K; PKC; POSITRON EMISSION TOMOGRAPHY; PROTEIN KINASE B; PROTEIN KINASE C; RAAS; REACTIVE OXYGEN SPECIES; REGULATORY T CELLS; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; ROS; S6K; SNS; SOC3-3; SUPEROXIDE DISMUTASE; SYMPATHETIC NERVOUS SYSTEM; T2DM; TGF-Β; TLR-4; TNF-Α; TOLL-LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA; TREGS; TUMOR NECROSIS FACTOR ALPHA; TYPE 2 DIABETES MELLITUS; URIC ACID; WAT; WD; WESTERN DIET; WHITE ADIPOSE TISSUE;

ADAPTIVE IMMUNITY; ANIMALS; CARDIO-RENAL SYNDROME; CARDIOVASCULAR SYSTEM; DIABETES MELLITUS; DISEASE PROGRESSION; HUMANS; HYPERTENSION, RENAL; INFLAMMATION; INSULIN; INSULIN RESISTANCE; LYMPHOCYTES; MACROPHAGES; OBESITY; PREMENOPAUSE; RECEPTOR, INSULIN; RENIN-ANGIOTENSIN SYSTEM; SEDENTARY LIFESTYLE; SEX FACTORS; T-LYMPHOCYTES, REGULATORY;

EID: 84886400216     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2013.07.001     Document Type: Review

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