-
1
-
-
0001573227
-
Obesity
-
Isselbacher KJ, Braunwald E, Wilson JD, Martin JB, Fauci AS, Kasper DL. eds. New York: McGraw-Hill
-
Olefsky JM. 1994 Obesity. In: Isselbacher KJ, Braunwald E, Wilson JD, Martin JB, Fauci AS, Kasper DL. eds. Harrison's principles of internal medicine. New York: McGraw-Hill; 446-452.
-
(1994)
Harrison's Principles of Internal Medicine
, pp. 446-452
-
-
Olefsky, J.M.1
-
2
-
-
0029974877
-
Adipose tissue leptin production and plasma leptin kinetics in humans
-
Klein S, Coppack SW, Mohamed-Ali V, Landt M. 1996 Adipose tissue leptin production and plasma leptin kinetics in humans. Diabetes. 45:984-987.
-
(1996)
Diabetes
, vol.45
, pp. 984-987
-
-
Klein, S.1
Coppack, S.W.2
Mohamed-Ali, V.3
Landt, M.4
-
3
-
-
0343981323
-
Role of non-esterified fatty acids in the metabolic changes of obesity
-
Frayn KN. 1996 Role of non-esterified fatty acids in the metabolic changes of obesity. Int J Obes Rel Metab Dis. 20(Suppl 4):7-10.
-
(1996)
Int J Obes Rel Metab Dis
, vol.20
, Issue.4 SUPPL.
, pp. 7-10
-
-
Frayn, K.N.1
-
4
-
-
0031054698
-
Depot- and sex-specific differences in human leptin mRNA expression: Implications for the control of regional fat distribution
-
Montague CT, Prins JB, Sanders L, Digby JE, O'Rahilly S. 1997 Depot- and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution. Diabetes. 46:342-347.
-
(1997)
Diabetes
, vol.46
, pp. 342-347
-
-
Montague, C.T.1
Prins, J.B.2
Sanders, L.3
Digby, J.E.4
O'Rahilly, S.5
-
5
-
-
0028931724
-
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
-
Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. 1995 Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest. 95:409-415.
-
(1995)
J Clin Invest
, vol.95
, pp. 409-415
-
-
Hotamisligil, G.S.1
Arner, P.2
Caro, J.F.3
Atkinson, R.L.4
Spiegelman, B.M.5
-
6
-
-
0026753927
-
Regulation of transcription factor mRNA accumulation during 3T3-L1 preadipocyte differentiation by tumor necrosis factor-alpha
-
Stephens JM, Butts MD, Pekala PH. 1992 Regulation of transcription factor mRNA accumulation during 3T3-L1 preadipocyte differentiation by tumor necrosis factor-alpha. J Mol Endocrinol. 9:61-72.
-
(1992)
J Mol Endocrinol
, vol.9
, pp. 61-72
-
-
Stephens, J.M.1
Butts, M.D.2
Pekala, P.H.3
-
7
-
-
0028968879
-
The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase
-
Kern PA, Saghizadeh M, Ong JM, Bosch RJ, Deem R, Simsolo RB. 1995 The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J Clin Invest. 95:2111-2119.
-
(1995)
J Clin Invest
, vol.95
, pp. 2111-2119
-
-
Kern, P.A.1
Saghizadeh, M.2
Ong, J.M.3
Bosch, R.J.4
Deem, R.5
Simsolo, R.B.6
-
8
-
-
0028787970
-
Aromatase activity and interleukin-6 production by normal and malignant breast tissues
-
Purohit A, Ghilchik MW, Duncan L, et al. 1995 Aromatase activity and interleukin-6 production by normal and malignant breast tissues. J Clin Endocrinol Metab. 80:3052-3058.
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 3052-3058
-
-
Purohit, A.1
Ghilchik, M.W.2
Duncan, L.3
-
9
-
-
0028825748
-
Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1
-
Kanety H, Feinstein R, Papa MZ, Hemi R, Karasik A. 1995 Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1. J Biol Chem. 270:23780-23784.
-
(1995)
J Biol Chem
, vol.270
, pp. 23780-23784
-
-
Kanety, H.1
Feinstein, R.2
Papa, M.Z.3
Hemi, R.4
Karasik, A.5
-
10
-
-
0030061922
-
IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha and obesity-induced insulin resistance
-
Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM. 1996 IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha and obesity-induced insulin resistance. Science. 271:665-668.
-
(1996)
Science
, vol.271
, pp. 665-668
-
-
Hotamisligil, G.S.1
Peraldi, P.2
Budavari, A.3
Ellis, R.4
White, M.F.5
Spiegelman, B.M.6
-
11
-
-
0027956188
-
Characterisation of differentiation factor/leukaemia inhibitory factor effect on lipoprotein lipase activity and mRNA in 3T3-L1 adipocytes
-
Berg M, Fraker DL, Alexander HR. 1994 Characterisation of differentiation factor/leukaemia inhibitory factor effect on lipoprotein lipase activity and mRNA in 3T3-L1 adipocytes. Cytokine. 6:425-432.
-
(1994)
Cytokine
, vol.6
, pp. 425-432
-
-
Berg, M.1
Fraker, D.L.2
Alexander, H.R.3
-
12
-
-
0026669452
-
Interleukin 6 reduces lipoprotein lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes: A possible role for interleukin 6 in cancer cachexia
-
Greenberg AS, Nordan RP, McIntosh J, Calvo JC, Scow RO, Jablons D. 1992 Interleukin 6 reduces lipoprotein lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes: a possible role for interleukin 6 in cancer cachexia. Cancer Res. 52:4113-4116.
-
(1992)
Cancer Res
, vol.52
, pp. 4113-4116
-
-
Greenberg, A.S.1
Nordan, R.P.2
McIntosh, J.3
Calvo, J.C.4
Scow, R.O.5
Jablons, D.6
-
13
-
-
0026660277
-
Role of cytokines in inducing hyperlipidaemia
-
Feingold KR, Grunfeld C. 1992 Role of cytokines in inducing hyperlipidaemia. Diabetes 41(Suppl 2):97-101.
-
(1992)
Diabetes
, vol.41
, Issue.2 SUPPL.
, pp. 97-101
-
-
Feingold, K.R.1
Grunfeld, C.2
-
14
-
-
0028245748
-
Effects of endotoxin and cytokines on lipid metabolism
-
Hardardottir I, Grunfeld C, Feingold KR. 1994 Effects of endotoxin and cytokines on lipid metabolism. Lipidology. 5:207-215.
-
(1994)
Lipidology
, vol.5
, pp. 207-215
-
-
Hardardottir, I.1
Grunfeld, C.2
Feingold, K.R.3
-
15
-
-
0026490127
-
Insulin resistance: An adaptation for weight maintenance
-
Eckel RH. 1992 Insulin resistance: an adaptation for weight maintenance. Lancet. 340:1452-1453.
-
(1992)
Lancet
, vol.340
, pp. 1452-1453
-
-
Eckel, R.H.1
-
16
-
-
0027495327
-
The role of interleukin-6 in lipopolysaccharide-induced weight loss, hypoglycaemia and fibrinogen production, in vivo
-
Strassmann G, Fong M, Windsor S, Neta R. 1993 The role of interleukin-6 in lipopolysaccharide-induced weight loss, hypoglycaemia and fibrinogen production, in vivo. Cytokine. 5:285-290.
-
(1993)
Cytokine
, vol.5
, pp. 285-290
-
-
Strassmann, G.1
Fong, M.2
Windsor, S.3
Neta, R.4
-
17
-
-
0028321429
-
Interleukin-6 an endocrine cytokine
-
Oxf
-
Jones TH. 1994 Interleukin-6 an endocrine cytokine. Clin Endocrinol (Oxf). 40:703-713.
-
(1994)
Clin Endocrinol
, vol.40
, pp. 703-713
-
-
Jones, T.H.1
-
19
-
-
0029915515
-
Phenylalanine kinetics in human adipose tissue
-
Coppack SW, Persson M, Miles JM. 1996 Phenylalanine kinetics in human adipose tissue. J Clin Invest. 98:692-697.
-
(1996)
J Clin Invest
, vol.98
, pp. 692-697
-
-
Coppack, S.W.1
Persson, M.2
Miles, J.M.3
-
20
-
-
0024508821
-
Effects of growth hormone on insulin sensitivity and forearm metabolism in normal man
-
Møller N, Butler PC, Antsiferov MA, Alberti KGMM. 1989 Effects of growth hormone on insulin sensitivity and forearm metabolism in normal man. Diabetologia. 32:105-110.
-
(1989)
Diabetologia
, vol.32
, pp. 105-110
-
-
Møller, N.1
Butler, P.C.2
Antsiferov, M.A.3
Alberti, K.G.M.M.4
-
21
-
-
0023554099
-
The measurement of metabolic exchange across muscle beds
-
Butler PC, Home PD. 1989 The measurement of metabolic exchange across muscle beds. Bailliere Clin Endocrinol Metab. 1:863-878.
-
(1989)
Bailliere Clin Endocrinol Metab
, vol.1
, pp. 863-878
-
-
Butler, P.C.1
Home, P.D.2
-
22
-
-
0027184803
-
Assessment of adipose tissue metabolism in man: Comparison of Fick and microdialysis techniques
-
Arner P, Bülow J. 1993 Assessment of adipose tissue metabolism in man: comparison of Fick and microdialysis techniques. Clin Sci. 85:247-256.
-
(1993)
Clin Sci
, vol.85
, pp. 247-256
-
-
Arner, P.1
Bülow, J.2
-
24
-
-
0029039563
-
Modification and validation of a commercially available portable detector for measurement of adipose tissue blood flow
-
Samra JS, Frayn KN, Giddings JA, Clark ML, Macdonald IA. 1995 Modification and validation of a commercially available portable detector for measurement of adipose tissue blood flow. Clin Physiol. 15:241-248.
-
(1995)
Clin Physiol
, vol.15
, pp. 241-248
-
-
Samra, J.S.1
Frayn, K.N.2
Giddings, J.A.3
Clark, M.L.4
Macdonald, I.A.5
-
25
-
-
85047693039
-
Plasma clearance, organ distribution and target cells of interleukin-6/hepatocyte-stimulating factor in the rat
-
Castell JV, Geiger T, Gross V, et al. 1988 Plasma clearance, organ distribution and target cells of interleukin-6/hepatocyte-stimulating factor in the rat. Eur J Biochem. 177:357-361.
-
(1988)
Eur J Biochem
, vol.177
, pp. 357-361
-
-
Castell, J.V.1
Geiger, T.2
Gross, V.3
-
26
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargill NS, Spiegelman BM. 1993 Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 259:87-91.
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
27
-
-
84907112362
-
Pharmacokinetics of murine tumor necrosis factor
-
Flick DA, Gifford GE. 1986 Pharmacokinetics of murine tumor necrosis factor. J Immunopharmacol. 8:89-97.
-
(1986)
J Immunopharmacol
, vol.8
, pp. 89-97
-
-
Flick, D.A.1
Gifford, G.E.2
-
28
-
-
0029906375
-
Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycaemic control in patients with NIDDM
-
Ofei F, Hurel S, Newkirk J, Sopwith M, Taylor R. 1996 Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycaemic control in patients with NIDDM. Diabetes. 45:881-885.
-
(1996)
Diabetes
, vol.45
, pp. 881-885
-
-
Ofei, F.1
Hurel, S.2
Newkirk, J.3
Sopwith, M.4
Taylor, R.5
-
29
-
-
0024253487
-
Are regional metabolic differences of adipose tissue responsible for different risks of obesity?
-
Björntorp P. 1988 Are regional metabolic differences of adipose tissue responsible for different risks of obesity? Horm Metab Res. 19(Suppl):23-25.
-
(1988)
Horm Metab Res
, vol.19
, Issue.SUPPL.
, pp. 23-25
-
-
Björntorp, P.1
-
30
-
-
0029925424
-
Periprandial systemic and regional lipase activity in normal man
-
Coppack SW, Yost TJ, Fisher RM, Eckel RH, Miles JM. 1996 Periprandial systemic and regional lipase activity in normal man. Am J Physiol. 270:E718-E722.
-
(1996)
Am J Physiol
, vol.270
-
-
Coppack, S.W.1
Yost, T.J.2
Fisher, R.M.3
Eckel, R.H.4
Miles, J.M.5
-
31
-
-
0345587248
-
Post-prandial generation of acylation stimulating protein by human adipose tissue in vivo
-
Abstract 190
-
Cianflone K, Sniderman AD, Summers LKM, Fielding BA, Frayn KN. Post-prandial generation of acylation stimulating protein by human adipose tissue in vivo. Proc Nutr Soc. 56(Suppl 2):Abstract 190.
-
Proc Nutr Soc
, vol.56
, Issue.2 SUPPL.
-
-
Cianflone, K.1
Sniderman, A.D.2
Summers, L.K.M.3
Fielding, B.A.4
Frayn, K.N.5
-
32
-
-
0002197106
-
Adipose tissue leptin production at fasting and after a high carbohydrate meal
-
Mohamed-Ali V, Goodrick SJ, Stanner SA, Rawesh A, Yudkin JS, Coppack SW. 1996 Adipose tissue leptin production at fasting and after a high carbohydrate meal [Abstract]. Diabet Med. 13:A10.
-
(1996)
Diabet Med
, vol.13
-
-
Mohamed-Ali, V.1
Goodrick, S.J.2
Stanner, S.A.3
Rawesh, A.4
Yudkin, J.S.5
Coppack, S.W.6
-
33
-
-
0027155267
-
Control of aromatase activity in breast cancer cells: The role of cytokines and growth factors
-
Reed MJ, Topping L, Coldham NG, Purohit A, Ghilchik MW, James VH. 1993 Control of aromatase activity in breast cancer cells: the role of cytokines and growth factors. J Steroid Biochem Mol Biol. 44:589-596.
-
(1993)
J Steroid Biochem Mol Biol
, vol.44
, pp. 589-596
-
-
Reed, M.J.1
Topping, L.2
Coldham, N.G.3
Purohit, A.4
Ghilchik, M.W.5
James, V.H.6
-
34
-
-
0028069629
-
CNS regulation of thermogenesis
-
Rothwell NJ. 1994 CNS regulation of thermogenesis. Crit Rev Neurobiol. 8:1-10.
-
(1994)
Crit Rev Neurobiol
, vol.8
, pp. 1-10
-
-
Rothwell, N.J.1
-
35
-
-
0027891770
-
Cytokines and hypothalamic-pituitary function
-
Jones JH, Kennedy RI. 1993 Cytokines and hypothalamic-pituitary function. Cytokine. 5:531-538.
-
(1993)
Cytokine
, vol.5
, pp. 531-538
-
-
Jones, J.H.1
Kennedy, R.I.2
-
36
-
-
0029863684
-
Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters
-
Grunfeld C, Zhao C, Fuller J, et al. 1996 Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters. J Clin Invest. 97:2152-2157.
-
(1996)
J Clin Invest
, vol.97
, pp. 2152-2157
-
-
Grunfeld, C.1
Zhao, C.2
Fuller, J.3
-
37
-
-
17344384196
-
Multiple cytokines and acute inflammation raise mouse leptin levels: Potential role in inflammatory anorexia
-
Sarraf P, Frederich RC, Turner EM, et al. 1997 Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia. J Exp Med. 185:171-175.
-
(1997)
J Exp Med
, vol.185
, pp. 171-175
-
-
Sarraf, P.1
Frederich, R.C.2
Turner, E.M.3
-
38
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartaglia LA, Dembski M, Weng X, et al. 1995 Identification and expression cloning of a leptin receptor, OB-R. Cell. 83:1263-1271.
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
-
39
-
-
84889536968
-
Positional cloning of the mouse obese gene
-
Zhang Y, Proenca R, Maffei M, Barone E, Leopold L, Friedman JM. 1994 Positional cloning of the mouse obese gene. Nature. 269:540-543.
-
(1994)
Nature
, vol.269
, pp. 540-543
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, E.4
Leopold, L.5
Friedman, J.M.6
-
40
-
-
0029048408
-
Recombinant mouse OB profein: Evidence for a peripheral signal linking adiposity and central neural networks
-
Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P. 1995 Recombinant mouse OB profein: evidence for a peripheral signal linking adiposity and central neural networks. Science. 269:546-549.
-
(1995)
Science
, vol.269
, pp. 546-549
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Burn, P.5
|