Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis

Nature Medicine

Volumn 15, Issue 12, 2009, Pages 1383-1391

  Erbay, Ebru ^a   Babaev, Vladimir R ^b   Mayers, Jared R ^a   Makowski, Liza ^c   Charles, Khanichi N ^a   Snitow, Melinda E ^a   Fazio, Sergio ^b   Wiest, Michelle M ^d   Watkins, Steven M ^d   Linton, MacRae F ^b   Hotamisligil, Gökhan S ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d Lipomics Technologies   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; CASPASE 3; CHAPERONE; FATTY ACID BINDING PROTEIN 4; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; LIPID; LIVER X RECEPTOR; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; MEMBRANE PROTEIN; MONOUNSATURATED FATTY ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHOLIPID; PROTEIN C JUN; PROTEIN MOMA 2; PROTEIN PERK; STRESS ACTIVATED PROTEIN KINASE; TRIACYLGLYCEROL; TUBULIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HOMEOSTASIS; HYPERLIPIDEMIA; LIPID METABOLISM; LIPOGENESIS; MACROPHAGE; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ATHEROSCLEROSIS; ENDOPLASMIC RETICULUM; HUMANS; LIPID METABOLISM; MACROPHAGES; OXIDATIVE STRESS;

EID: 71549152580     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2067     Document Type: Article

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