Free fatty acids and cytokines induce pancreatic β-cell apoptosis by different mechanisms: Role of nuclear factor-κB and endoplasmic reticulum stress

Endocrinology

Volumn 145, Issue 11, 2004, Pages 5087-5096

  Kharroubi, Ilham ^a   Ladrière, Laurence ^a   Cardozo, Alessandra K ^a   Dogusan, Zeynep ^a   Cnop, Miriam ^a   Eizirik, Décio L ^a,b  

^a ERASME HOSPITAL   (Belgium)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; FATTY ACID; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN HEAVY CHAIN; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE SYNTHASE; OLEIC ACID; PALMITIC ACID; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ADIPOCYTE; ALTERNATIVE RNA SPLICING; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL DESTRUCTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FLUORESCENCE ACTIVATED CELL SORTING; INSULIN DEPENDENT DIABETES MELLITUS; INSULINOMA; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; CARCINOGENS; CELL LINE, TUMOR; CYTOKINES; DRUG SYNERGISM; ENDOPLASMIC RETICULUM; FATTY ACIDS, NONESTERIFIED; FLOW CYTOMETRY; INSULINOMA; INTERFERON TYPE II; INTERLEUKIN-1; ISLETS OF LANGERHANS; MALE; NF-KAPPA B; OLEIC ACID; PALMITATES; PANCREATIC NEOPLASMS; RATS; RATS, WISTAR; THAPSIGARGIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 9244231766     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2004-0478     Document Type: Article

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