ER Stress Causes Rapid Loss of Intestinal Epithelial Stemness through Activation of the Unfolded Protein Response

Cell Reports

Volumn 3, Issue 4, 2013, Pages 1128-1139

  Heijmans, Jarom ^a   Van Lidth de Jeude, Jooske F ^a   Koo, Bon Kyoung ^c   Rosekrans, Sanne L ^a   Wielenga, Mattheus C B ^a   Van De Wetering, Marc ^c   Ferrante, Marc ^c   Lee, Amy S ^d   Onderwater, Jos J M ^b   Paton, James C ^e   Paton, Adrienne W ^e   Mommaas, A Mieke ^b   Kodach, Liudmila L ^b   Hardwick, James C ^b   Hommes, Daniël W ^b,f   Clevers, Hans ^c   Muncan, Vanesa ^a   Van Den Brink, Gijs R ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c HUBRECHT INSTITUTE   (Netherlands)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e UNIVERSITY OF ADELAIDE   (Australia)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 2ALPHA; MEMBRANE RECEPTOR; PROTEIN PERK; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CELL CULTURE; CELL DIFFERENTIATION; CELL TRANSFORMATION; CONTROLLED STUDY; CYTOPLASM; ENDOPLASMIC RETICULUM STRESS; INTESTINE EPITHELIUM; INTESTINE EPITHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL; UNFOLDED PROTEIN RESPONSE;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; EUKARYOTIC INITIATION FACTOR-2; HEAT-SHOCK PROTEINS; INTESTINAL MUCOSA; MICE; MUTATION; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STEM CELLS; UNFOLDED PROTEIN RESPONSE;

EID: 84876998128     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2013.02.031     Document Type: Article

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