Sphingosine 1-phosphate and sphingosine kinases in health and disease: Recent advances

Progress in Lipid Research

Volumn 62, Issue , 2016, Pages 93-106

  Pyne, Susan ^a   Adams, David R ^b   Pyne, Nigel J ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b HERIOT WATT UNIVERSITY   (United Kingdom)

Author keywords

Intracellular signalling; S1P receptors; Sphingosine 1 phosphate; Sphingosine kinase; Sphingosine kinase inhibitors

Indexed keywords

2 (4 HYDROXYANILINO) 4 (4 CHLOROPHENYL)THIAZOLE; 2 (HYDROXYMETHYL) 1 [4 [[4 [4 (TRIFLUOROMETHYL)PHENYL]THIAZOL 2 YL]AMINO]PHENETHYL]PIPERIDIN 4 OL; 2 [3 (4 OCTYLPHENYL) 1,2,4 OXADIAZOL 5 YL]PYRROLIDINE 1 CARBOXIMIDAMIDE; 3 (2 AMINOETHYL) 5 [3 (4 BUTOXYLPHENYL)PROPYLIDENE]THIAZOLIDINE 2,4 DIONE; 3 (4 CHLOROPHENYL) N (4 PYRIDINYLMETHYL)ADAMANTANE 1 CARBOXAMIDE; 4 METHYL N [2 [[2 [(4 METHYLPHENYL)SULFONAMIDO]BENZYLIDENE]AMINO]PHENYL]BENZENESULFONAMIDE; BETA SECRETASE 1; FINGOLIMOD; FINGOLIMOD METHYLETHER; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; IMATINIB; MONOCLONAL ANTIBODY; N METHYL 5 (4 PENTYLPHENYL) 2 AMINOPENT 4 ENE 1,3 DIOL; NILOTINIB; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHOTRANSFERASE INHIBITOR; SMALL INTERFERING RNA; SPHINGOMAB; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE KINASE; SPHINGOSINE KINASE 1; SPHINGOSINE KINASE 2; TELOMERASE REVERSE TRANSCRIPTASE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG; [1 [4 [[3 METHYL 5 (PHENYLSULFONYLMETHYL)PHENOXY]METHYL]BENZYL]PYRROLIDIN 2 YL]METHANOL; G PROTEIN COUPLED RECEPTOR; LYSOPHOSPHOLIPID; PHOSPHOTRANSFERASE; PROTEIN KINASE INHIBITOR; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE;

ALZHEIMER DISEASE; BREAST CANCER; CATALYSIS; CRYSTAL STRUCTURE; DIABETES MELLITUS; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SELECTIVITY; DRUG SENSITIVITY; DRUG TARGETING; ENZYME INHIBITION; ENZYME STRUCTURE; GENE SILENCING; HEART INFARCTION; HUMAN; IC50; INFLAMMATION; LEUKEMIA; LUNG METASTASIS; LYMPH NODE METASTASIS; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN FUNCTION; PULMONARY HYPERTENSION; REVIEW; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; ULCERATIVE COLITIS; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CARDIOVASCULAR DISEASE; CHEMISTRY; DEGENERATIVE DISEASE; METABOLISM; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION;

ANIMALS; CARDIOVASCULAR DISEASES; DIABETES MELLITUS; HUMANS; INFLAMMATION; LYSOPHOSPHOLIPIDS; MODELS, MOLECULAR; NEOPLASMS; NEURODEGENERATIVE DISEASES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN KINASE INHIBITORS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; SPHINGOSINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84961778397     PISSN: 01637827     EISSN: 18732194     Source Type: Journal    
DOI: 10.1016/j.plipres.2016.03.001     Document Type: Review

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