Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis

EMBO Molecular Medicine

Volumn 4, Issue 8, 2012, Pages 761-775

  Ponnusamy, Suriyan ^a,b   Selvam, Shanmugam Panneer ^a,b   Mehrotra, Shikhar ^a,b   Kawamori, Toshihiko ^a,b   Snider, Ashley J ^a,b,c   Obeid, Lina M ^a,b,c   Shao, Yuan ^a,b   Sabbadini, Roger ^d   Ogretmen, Besim ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^d Lpath Inc   (United States)

Author keywords

Lung metastasis; Sphingolipids; Sphingomab; Sphingosine 1 phosphate; Sphingosine kinase 1

Indexed keywords

ANTINEOPLASTIC AGENT; BREAST CARCINOMA METASTASIS SUPPRESSOR 1; LT 1002; MESSENGER RNA; MONOCLONAL ANTIBODY; SMALL INTERFERING RNA; SPHINGOMAB; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 2; SPHINGOSINE KINASE 1; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER CANCER; BLOOD LEVEL; CANCER CELL; CANCER GROWTH; CANCER IMMUNOTHERAPY; CANCER MODEL; CELL COMMUNICATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE SILENCING; INTRACELLULAR SIGNALING; LUNG METASTASIS; MALE; METASTASIS INHIBITION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTATE CANCER; SIGNAL TRANSDUCTION;

ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; LUNG NEOPLASMS; LYSOPHOSPHOLIPIDS; MALE; MICE; MICE, KNOCKOUT; NEOPLASM METASTASIS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROSTATIC NEOPLASMS; RECEPTORS, LYSOSPHINGOLIPID; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; SPHINGOSINE; URINARY BLADDER NEOPLASMS;

EID: 84864797320     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201200244     Document Type: Article

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