Pulmonary Endothelial Cell Barrier Enhancement by Novel FTY720 Analogs: Methoxy-FTY720, Fluoro-FTY720, and β-Glucuronide-FTY720

Chemistry and Physics of Lipids

Volumn 191, Issue , 2015, Pages 16-24

  Camp, Sara M ^a   Chiang, Eddie T ^a   Sun, Chaode ^c   Usatyuk, Peter V ^b   Bittman, Robert ^c   Natarajan, Viswanathan ^b   Garcia, Joe G N ^a   Dudek, Steven M ^b  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Acute respiratory distress syndrome; Endothelial barrier regulation; FTY720; G protein couple receptors; Sphingosine 1 phosphate

Indexed keywords

ACTIN; BETA GLUCURONIDE FINGOLIMOD; DEXTRAN; FINGOLIMOD; FLUORO FINGOLIMOD; G PROTEIN COUPLED RECEPTOR; METHOXY FINGOLIMOD; MITOGEN ACTIVATED PROTEIN KINASE; MYOSIN LIGHT CHAIN; SPHINGOSINE 1 PHOSPHATE; UNCLASSIFIED DRUG; CALCIUM; FLUORIDE; GLUCURONIDE; LYSOPHOSPHOLIPID; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE;

ARTICLE; BLOOD VESSEL PERMEABILITY; CALCIUM CELL LEVEL; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; LIPID RAFT; LUNG ENDOTHELIUM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSENDOTHELIAL MONOLAYER ELECTRICAL RESISTANCE; ANALOGS AND DERIVATIVES; CELL LINE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; FLUORESCENCE MICROSCOPY; METABOLISM; PERMEABILITY; PHOSPHORYLATION; PULMONARY ARTERY;

CALCIUM; CELL LINE; ENDOTHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FINGOLIMOD HYDROCHLORIDE; FLUORIDES; GLUCURONIDES; HUMANS; LYSOPHOSPHOLIPIDS; MICROSCOPY, FLUORESCENCE; PERMEABILITY; PHOSPHORYLATION; PULMONARY ARTERY; SIGNAL TRANSDUCTION; SPHINGOSINE;

EID: 84939223850     PISSN: 00093084     EISSN: 18732941     Source Type: Journal    
DOI: 10.1016/j.chemphyslip.2015.08.004     Document Type: Article

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